Detailed information for compound 1600562

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 462.006 | Formula: C26H24ClN3OS
  • H donors: 1 H acceptors: 1 LogP: 6.45 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)C(=O)c1c(csc1N)CN1CCN(CC1)c1cccc2c1cccc2
  • InChi: 1S/C26H24ClN3OS/c27-21-10-8-19(9-11-21)25(31)24-20(17-32-26(24)28)16-29-12-14-30(15-13-29)23-7-3-5-18-4-1-2-6-22(18)23/h1-11,17H,12-16,28H2
  • InChiKey: RITYNZBWVKWGFS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0023 0.0034 0.004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0132 0.0132
Loa Loa (eye worm) TK/EGFR protein kinase 0.0144 0.0921 0.107
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Brugia malayi ephrin receptor 1 precursor 0.0091 0.0535 0.0622
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0054 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0266 0.047
Echinococcus multilocularis tubulin, beta 4A class IVa 0.077 0.5527 0.5527
Brugia malayi Serotonin receptor 0.0363 0.2531 0.2939
Echinococcus granulosus Furin 1 0.0303 0.2088 0.2088
Echinococcus multilocularis MAGUK p55 subfamily 0.0023 0.0035 0.0035
Echinococcus multilocularis beta tubulin 0.077 0.5527 0.5527
Schistosoma mansoni hypothetical protein 0.0023 0.0034 0.0036
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0062
Leishmania major beta tubulin 0.077 0.5527 1
Trypanosoma brucei calpain-like protein, putative 0.0113 0.0696 0.125
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0174 0.1146 0.1146
Toxoplasma gondii PAN domain-containing protein 0.0289 0.1992 0.3604
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0363 0.2531 0.2531
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0363 0.2531 0.2531
Loa Loa (eye worm) hypothetical protein 0.0063 0.0324 0.0377
Echinococcus granulosus orexin receptor type 2 0.0363 0.2531 0.2531
Echinococcus multilocularis guanylate kinase 0.0019 0.0006 0.0006
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0019 0.0002 0.0003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0363 0.2531 0.2939
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0054 0.0062
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.004 0.016 0.0159
Echinococcus granulosus serotonin receptor 0.0363 0.2531 0.2531
Toxoplasma gondii subtilisin SUB4 0.0055 0.0266 0.0481
Loa Loa (eye worm) hypothetical protein 0.0055 0.0266 0.0308
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus granulosus GPCR family 2 0.0063 0.0324 0.0324
Loa Loa (eye worm) guanylate kinase 0.0023 0.0035 0.0041
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0797 0.5724 0.5723
Brugia malayi nuclear receptor NHR-88 0.0026 0.0054 0.0062
Echinococcus multilocularis NMDA receptor 0.0032 0.0098 0.0097
Onchocerca volvulus 0.0021 0.002 0.0044
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0054 0.0056
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0055 0.0266 0.5716
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0055 0.0266 0.5663
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0145 0.0145
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0363 0.2531 0.2659
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.0132 0.0132
Loa Loa (eye worm) BEN-1 protein 0.077 0.5527 0.6418
Schistosoma mansoni coup transcription factor 0.0026 0.0054 0.0056
Echinococcus granulosus guanylate kinase 0.0019 0.0006 0.0006
Giardia lamblia Beta tubulin 0.077 0.5527 1
Onchocerca volvulus 0.0363 0.2531 0.559
Onchocerca volvulus 0.0363 0.2531 0.559
Schistosoma mansoni hypothetical protein 0.0038 0.0145 0.0152
Onchocerca volvulus 0.0363 0.2531 0.559
Schistosoma mansoni histamine h1 receptor 0.0363 0.2531 0.2659
Echinococcus granulosus Tubulin beta 2C chain 0.077 0.5527 0.5527
Trypanosoma brucei beta tubulin 0.077 0.5527 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.0696 0.125
Giardia lamblia Beta tubulin 0.077 0.5527 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0363 0.2531 0.2531
Loa Loa (eye worm) hypothetical protein 0.0049 0.0226 0.0263
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0079 0.0083
Trichomonas vaginalis tubulin alpha chain, putative 0.077 0.5527 1
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0361 0.252 0.2926
Schistosoma mansoni hypothetical protein 0.0063 0.0324 0.034
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1726 0.3116
Loa Loa (eye worm) hypothetical protein 0.0634 0.4528 0.5258
Brugia malayi sulfakinin receptor protein 0.0363 0.2531 0.2939
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0363 0.2531 0.2531
Schistosoma mansoni apoptosis regulator bax 0.014 0.089 0.0935
Trypanosoma cruzi subtilisin peptidase 0.0055 0.0266 0.047
Schistosoma mansoni MAGUK homolog 0.0023 0.0035 0.0037
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.0049 0.0226 0.0226
Schistosoma mansoni amine GPCR 0.0363 0.2531 0.2659
Brugia malayi SRC-1 0.004 0.016 0.0185
Schistosoma mansoni biogenic amine receptor 0.0363 0.2531 0.2659
Echinococcus granulosus high voltage activated calcium channel beta 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.119 0.8612 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0069 0.0369 0.0388
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0114 0.0699 0.0699
Brugia malayi endoprotease bli-4 precursor 0.119 0.8612 1
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0054 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0363 0.2531 0.2659
Leishmania major C-8 sterol isomerase-like protein 0.0361 0.252 0.4554
Schistosoma mansoni hypothetical protein 0.0363 0.2531 0.2659
Schistosoma mansoni neuropeptide receptor 0.0363 0.2531 0.2659
Trypanosoma brucei beta tubulin 0.077 0.5527 1
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.0132 0.0132
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.016 0.0159
Echinococcus granulosus disks large 3 0.0023 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0164 0.1071 0.1243
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0062
Echinococcus multilocularis epidermal growth factor receptor 0.0144 0.0921 0.0921
Echinococcus multilocularis Tubulin beta 2C chain 0.077 0.5527 0.5527
Schistosoma mansoni hypothetical protein 0.0032 0.0098 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.1146 0.1204
Brugia malayi Glutamate receptor 2 precursor 0.0032 0.0098 0.0113
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0363 0.2531 0.2659
Entamoeba histolytica tubulin family protein 0.077 0.5527 1
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0019 0.0006 0.0007
Entamoeba histolytica tubulin family protein 0.077 0.5527 1
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0266 0.047
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0055 0.0266 0.0279
Loa Loa (eye worm) melatonin receptor type 1A 0.0363 0.2531 0.2939
Echinococcus multilocularis nmda type glutamate receptor 0.0114 0.0699 0.0699
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Schistosoma mansoni site-1 peptidase (S08 family) 0.0055 0.0266 0.0279
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1726 0.3116
Trypanosoma brucei subtilisin peptidase 0.0055 0.0266 0.047
Brugia malayi Glutamate receptor 1 precursor 0.0032 0.0098 0.0113
Onchocerca volvulus 0.0187 0.124 0.274
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0303 0.2088 0.3771
Onchocerca volvulus 0.0019 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0266 0.047
Schistosoma mansoni opsin-like receptor 0.0363 0.2531 0.2659
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Brugia malayi hypothetical protein 0.0019 0.0006 0.0007
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0054 0.0062
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0055 0.0266 0.0308
Loa Loa (eye worm) hypothetical protein 0.0095 0.0564 0.0655
Brugia malayi Serotonin receptor 0.0363 0.2531 0.2939
Echinococcus granulosus furin 0.119 0.8612 0.8612
Trichomonas vaginalis tubulin epsilon chain, putative 0.077 0.5527 1
Schistosoma mansoni hypothetical protein 0.014 0.089 0.0935
Loa Loa (eye worm) apoptosis regulator protein 0.014 0.089 0.1034
Schistosoma mansoni glutamate receptor NMDA 0.0048 0.0218 0.0229
Loa Loa (eye worm) proprotein convertase 2 0.0303 0.2088 0.2425
Brugia malayi abnormal cell lineage protein 2 0.0019 0.0006 0.0007
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0032 0.0098 0.0097
Schistosoma mansoni hypothetical protein 0.0248 0.1685 0.1771
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0054 0.0056
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0363 0.2531 0.2939
Brugia malayi Tachykinin-like peptides receptor 99D 0.0813 0.5844 0.6785
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0104 0.0104
Schistosoma mansoni tyrosine kinase 0.002 0.0006 0.0007
Loa Loa (eye worm) subtilase 0.0055 0.0266 0.0308
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0054 0.0056
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0055 0.0266 0.0279
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Schistosoma mansoni MAGUK homolog 0.0024 0.0039 0.004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0054 0.0062
Echinococcus granulosus g protein coupled receptor 0.0363 0.2531 0.2531
Echinococcus granulosus tyrosine protein kinase Src42A 0.0033 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0363 0.2531 0.2531
Brugia malayi G-protein coupled receptor 0.0363 0.2531 0.2939
Loa Loa (eye worm) TYRA-2 protein 0.0363 0.2531 0.2939
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0062
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0145 0.0145
Brugia malayi Melatonin receptor type 1A 0.0363 0.2531 0.2939
Loa Loa (eye worm) hypothetical protein 0.0456 0.3213 0.3731
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0048 0.0218 0.0218
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0054 0.0056
Leishmania major beta tubulin 0.077 0.5527 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0363 0.2531 0.2939
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0062
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.0132 0.0132
Schistosoma mansoni growth hormone secretagogue receptor 0.0363 0.2531 0.2659
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0054 0.0062
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0024 0.0039 0.0038
Schistosoma mansoni amine GPCR 0.0363 0.2531 0.2659
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.002 0.0006 0.0014
Brugia malayi nuclear hormone receptor 0.0026 0.0054 0.0062
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Onchocerca volvulus 0.0363 0.2531 0.559
Toxoplasma gondii subtilisin SUB7 0.0055 0.0266 0.0481
Echinococcus granulosus beta tubulin 0.077 0.5527 0.5527
Leishmania major beta tubulin 0.077 0.5527 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0003
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Leishmania major beta tubulin 0.077 0.5527 1
Leishmania major beta tubulin 0.077 0.5527 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.004
Echinococcus multilocularis neuropeptide receptor 0.0363 0.2531 0.2531
Schistosoma mansoni maguk P55 subfamily member 26 0.0019 0.0006 0.0006
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0363 0.2531 0.559
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0363 0.2531 0.2659
Loa Loa (eye worm) hypothetical protein 0.0813 0.5844 0.6785
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus granulosus epidermal growth factor receptor 0.0144 0.0921 0.0921
Trichomonas vaginalis tubulin beta chain, putative 0.077 0.5527 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0363 0.2531 0.2659
Onchocerca volvulus 0.0028 0.0066 0.0146
Brugia malayi follicle stimulating hormone receptor 0.0363 0.2531 0.2939
Echinococcus multilocularis MAGUK p55 subfamily 0.0023 0.0035 0.0035
Echinococcus multilocularis g protein coupled receptor 0.0363 0.2531 0.2531
Schistosoma mansoni amine GPCR 0.0363 0.2531 0.2659
Schistosoma mansoni neuropeptide f receptor 76f 0.0363 0.2531 0.2659
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0303 0.2088 0.3771
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Loa Loa (eye worm) TK/ALK protein kinase 0.0026 0.0057 0.0067
Schistosoma mansoni tubulin subunit beta 0.077 0.5527 0.5807
Echinococcus granulosus Tubulin beta 2C chain 0.077 0.5527 0.5527
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0062
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0049 0.0226 0.0238
Giardia lamblia Beta tubulin 0.077 0.5527 1
Echinococcus granulosus neuropeptide Y receptor 0.0363 0.2531 0.2531
Trypanosoma brucei hypothetical protein 0.0113 0.0696 0.125
Leishmania major beta tubulin 0.077 0.5527 1
Brugia malayi celfurPC protein 0.0942 0.679 0.7884
Echinococcus granulosus tubulin beta 1 chain 0.077 0.5527 0.5527
Loa Loa (eye worm) TK protein kinase 0.0033 0.0104 0.0121
Brugia malayi neuroendocrine convertase 1 precursor 0.0758 0.5438 0.6315
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0253 0.1726 0.2005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Schistosoma mansoni tubulin subunit beta 0.077 0.5527 0.5807
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.2983 0.2983
Echinococcus multilocularis fmrfamide receptor 0.0363 0.2531 0.2531
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0054 0.0062
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Brugia malayi Protein kinase domain containing protein 0.0021 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Schistosoma mansoni hypothetical protein 0.0063 0.0324 0.034
Echinococcus granulosus biogenic amine 5HT receptor 0.0363 0.2531 0.2531
Echinococcus multilocularis G protein coupled receptor 139 0.0363 0.2531 0.2531
Echinococcus multilocularis rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Echinococcus granulosus alpha 1A adrenergic receptor 0.0363 0.2531 0.2531
Echinococcus multilocularis tubulin subunit beta 0.077 0.5527 0.5527
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0055 0.0266 0.047
Echinococcus granulosus neuropeptides capa receptor 0.0363 0.2531 0.2531
Schistosoma mansoni opsin-like receptor 0.0363 0.2531 0.2659
Onchocerca volvulus 0.0363 0.2531 0.559
Echinococcus granulosus rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.0696 0.125
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0361 0.252 0.4554
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Onchocerca volvulus 0.0363 0.2531 0.559
Echinococcus granulosus g-protein coupled receptor 0.0363 0.2531 0.2531
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0054 0.0062
Schistosoma mansoni cell polarity protein 0.0023 0.0035 0.0037
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis MAGUK p55 subfamily 0.0023 0.0035 0.0035
Leishmania major beta tubulin 0.077 0.5527 1
Schistosoma mansoni tubulin subunit beta 0.077 0.5527 0.5807
Leishmania major beta tubulin 0.077 0.5527 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0007
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0054 0.0056
Brugia malayi neuropeptide F receptor 0.0363 0.2531 0.2939
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0324 0.0324
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0363 0.2531 0.2659
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0054 0.0062
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0113 0.0696 0.125
Onchocerca volvulus 0.0019 0 0.0001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0363 0.2531 0.2531
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Brugia malayi Receptor family ligand binding region containing protein 0.002 0.0006 0.0007
Echinococcus multilocularis neuropeptide Y receptor 0.0363 0.2531 0.2531
Brugia malayi Tubulin beta-1 chain 0.077 0.5527 0.6418
Schistosoma mansoni replication factor A 1 rfa1 0.0034 0.0113 0.0118
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0034 0.0113 0.0193
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Schistosoma mansoni hypothetical protein 0.0023 0.0034 0.0036
Loa Loa (eye worm) RGC/RGC protein kinase 0.002 0.0006 0.0007
Echinococcus granulosus peptide allatostatin:somatostatin 0.0363 0.2531 0.2531
Loa Loa (eye worm) endoprotease bli-4 0.119 0.8612 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0054 0.0056
Schistosoma mansoni site-1 peptidase (S08 family) 0.0055 0.0266 0.0279
Brugia malayi G protein-coupled receptor 0.0363 0.2531 0.2939
Echinococcus granulosus tubulin beta 4A class IVa 0.077 0.5527 0.5527
Schistosoma mansoni hypothetical protein 0.0314 0.217 0.228
Entamoeba histolytica hypothetical protein 0.0038 0.0145 0.0251
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1378 1 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0248 0.1685 0.3042
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0185 0.1221 0.1418
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0032 0.01 0.0171
Echinococcus granulosus hypothetical protein 0.0363 0.2531 0.2531
Leishmania major beta tubulin 0.077 0.5527 1
Toxoplasma gondii subtilisin SUB12 0.0073 0.0403 0.0729
Brugia malayi Guanylate kinase family protein 0.0023 0.0035 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0062
Echinococcus granulosus tachykinin peptides receptor 99D 0.0363 0.2531 0.2531
Echinococcus granulosus glutamate NMDA receptor subunit 0.0269 0.1842 0.1842
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1726 0.3116
Schistosoma mansoni neuropeptide F-like receptor 0.0363 0.2531 0.2659
Echinococcus granulosus receptor type guanylyl cyclase 0.002 0.0006 0.0006
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis neuropeptide receptor 0.0363 0.2531 0.2531
Schistosoma mansoni protein kinase 0.002 0.0006 0.0007
Echinococcus granulosus Tubulin beta 2C chain 0.077 0.5527 0.5527
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0066 0.0345 0.0614
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0048 0.0218 0.0218
Plasmodium vivax tubulin beta chain, putative 0.077 0.5527 1
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0266 0.047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0363 0.2531 0.2659
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1086 0.1956
Echinococcus multilocularis Tubulin beta 2C chain 0.077 0.5527 0.5527
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.0324 0.0324
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0324 0.0377
Echinococcus granulosus rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Entamoeba histolytica hypothetical protein 0.0038 0.0145 0.0251
Loa Loa (eye worm) neuropeptide F receptor 0.0363 0.2531 0.2939
Echinococcus multilocularis fmrfamide receptor 0.0363 0.2531 0.2531
Echinococcus multilocularis neuroendocrine convertase 2 0.0758 0.5438 0.5438
Leishmania major beta tubulin 0.077 0.5527 1
Schistosoma mansoni cell polarity protein 0.0023 0.0033 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Trypanosoma cruzi beta tubulin, putative 0.077 0.5527 1
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0019 0.0006 0.0006
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0055 0.0266 0.0308
Echinococcus multilocularis tyrosine protein kinase Fgr 0.004 0.016 0.0159
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.004 0.016 0.0159
Brugia malayi Guanylyl cyclase protein 23 0.002 0.0006 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0303 0.2088 0.3771
Brugia malayi ecdysteroid receptor 0.0026 0.0054 0.0062
Brugia malayi protein-tyrosine kinase 0.0037 0.0132 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1726 0.3116
Onchocerca volvulus 0.0363 0.2531 0.559
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Toxoplasma gondii subtilisin SUB8 0.0055 0.0266 0.0481
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0055 0.0266 0.0265
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0049 0.0226 0.0226
Echinococcus granulosus g protein coupled receptor 0.0363 0.2531 0.2531
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0055 0.0266 0.5663
Plasmodium falciparum subtilisin-like protease 2 0.0055 0.0266 0.047
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0032 0.0098 0.0097
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0055 0.0266 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Brugia malayi Subtilase family protein 0.0055 0.0266 0.0308
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0054 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0054 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0054 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1726 0.3116
Echinococcus multilocularis neuropeptide receptor A26 0.0363 0.2531 0.2531
Brugia malayi ORL1-like opioid receptor 0.0363 0.2531 0.2939
Onchocerca volvulus 0.0363 0.2531 0.559
Schistosoma mansoni ATP-binding cassette transporter 0.0032 0.0098 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0363 0.2531 0.2659
Echinococcus granulosus MAGUK p55 subfamily 0.0023 0.0035 0.0035
Echinococcus granulosus disks large 1 0.0019 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.0049 0.0226 0.0226
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0269 0.1842 0.1842
Echinococcus multilocularis Tubulin beta 2C chain 0.077 0.5527 0.5527
Echinococcus multilocularis rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0054 0.0054
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0054 0.0054
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0055 0.0266 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0113 0.0696 0.125
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0797 0.5724 0.5723
Echinococcus multilocularis 0.0069 0.0369 0.0369
Brugia malayi AKH receptor 0.0363 0.2531 0.2939
Loa Loa (eye worm) tubulin beta-2A chain 0.077 0.5527 0.6418
Echinococcus granulosus dnaJ subfamily B 0.0424 0.2983 0.2983
Mycobacterium ulcerans guanylate kinase 0.0019 0.0006 0.0123
Echinococcus multilocularis Furin 1 0.0303 0.2088 0.2088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0054 0.0056
Onchocerca volvulus 0.0363 0.2531 0.559
Schistosoma mansoni tyrosine kinase 0.004 0.016 0.0168
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0363 0.2531 0.2531
Onchocerca volvulus 0.0634 0.4528 1
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0019 0.0006 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Schistosoma mansoni serine-type protease inhibitor 0.1313 0.9517 1
Toxoplasma gondii beta tubulin 0.077 0.5527 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0303 0.2088 0.3771
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0104 0.0104
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0069 0.0369 0.0369
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1086 0.1956
Leishmania major beta tubulin 0.077 0.5527 1
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0145 0.0152
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Brugia malayi GnHR receptor homolog 0.0363 0.2531 0.2939
Echinococcus granulosus fmrfamide receptor 0.0363 0.2531 0.2531
Echinococcus multilocularis neuropeptide FF receptor 2 0.0813 0.5844 0.5843
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0363 0.2531 0.2531
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0079 0.0083
Echinococcus multilocularis sex peptide receptor 0.0363 0.2531 0.2531
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0055 0.0266 0.5663
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1086 0.1956
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0098 0.0102
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0032 0.0098 0.0097
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0174 0.1146 0.1331
Schistosoma mansoni maguk P55 subfamily member 35 0.0023 0.0035 0.0037
Schistosoma mansoni guanylate kinase 0.0019 0.0006 0.0006
Trichomonas vaginalis hypothetical protein 0.0248 0.1685 0.3042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0113 0.0696 0.125
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0032 0.0098 0.0097
Plasmodium vivax subtilisin-like serine protease, putative 0.0055 0.0266 0.047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0363 0.2531 0.2659
Echinococcus granulosus tubulin subunit beta 0.077 0.5527 0.5527
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0363 0.2531 0.2659
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.0696 0.125
Echinococcus multilocularis beta tubulin 0.077 0.5527 0.5527
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis G-protein coupled receptor, putative 0.0363 0.2531 0.2531
Echinococcus granulosus MAGUK p55 subfamily 0.0023 0.0035 0.0035
Onchocerca volvulus 0.0019 0 0.0001
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0048 0.0218 0.0218
Schistosoma mansoni biogenic amine (5HT) receptor 0.0363 0.2531 0.2659
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.014 0.089 0.089
Onchocerca volvulus 0.0019 0 0.0001
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0363 0.2531 0.2531
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.0132 0.0132
Leishmania major beta tubulin 0.077 0.5527 1
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0032 0.0098 0.0097
Loa Loa (eye worm) hypothetical protein 0.0361 0.252 0.2926
Echinococcus granulosus rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.0054 0.0119
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.004
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Schistosoma mansoni hypothetical protein 0.0063 0.0324 0.034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.0054 0.0119
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0034 0.0113 0.0131
Trichomonas vaginalis tubulin, putative 0.077 0.5527 1
Leishmania major beta tubulin 0.077 0.5527 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0113 0.0696 0.125
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.014 0.089 0.0935
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0363 0.2531 0.2939
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0019 0.0002 0.0003
Onchocerca volvulus 0.0363 0.2531 0.559
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0363 0.2531 0.2531
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0054 0.0062
Echinococcus granulosus MAGUK p55 subfamily 0.0023 0.0035 0.0035
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0024 0.0039 0.0038
Echinococcus multilocularis tubulin beta 1 chain 0.077 0.5527 0.5527
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.016 0.0159
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Schistosoma mansoni hypothetical protein 0.0424 0.2983 0.3134
Plasmodium falciparum subtilisin-like protease 1 0.0055 0.0266 0.047
Echinococcus granulosus membrane bound transcription factor site 1 0.0055 0.0266 0.0265
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.016 0.0159
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0363 0.2531 0.2659
Wolbachia endosymbiont of Brugia malayi guanylate kinase 0.0019 0.0006 0.5
Echinococcus granulosus 7tm_1 domain containing protein 0.0363 0.2531 0.2531
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.0696 0.125
Loa Loa (eye worm) glutamate receptor 2 0.0032 0.0098 0.0113
Onchocerca volvulus 0.0363 0.2531 0.559
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0048 0.0218 0.0218
Echinococcus granulosus Tubulin beta 2C chain 0.077 0.5527 0.5527
Echinococcus multilocularis receptor type guanylyl cyclase 0.002 0.0006 0.0006
Echinococcus multilocularis neuropeptides capa receptor 0.0363 0.2531 0.2531
Echinococcus multilocularis Tubulin beta 2C chain 0.077 0.5527 0.5527
Echinococcus multilocularis tyrosine kinase 0.002 0.0006 0.0006
Plasmodium falciparum subtilisin-like protease 3 0.0055 0.0266 0.047
Onchocerca volvulus 0.0363 0.2531 0.559
Loa Loa (eye worm) SRC-1 0.004 0.016 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0054 0.0062
Schistosoma mansoni neuropeptide F-like receptor 0.0363 0.2531 0.2659
Echinococcus multilocularis neuropeptide s receptor 0.0363 0.2531 0.2531
Echinococcus granulosus neuropeptide Y receptor 0.0363 0.2531 0.2531
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0054 0.0054
Schistosoma mansoni hypothetical protein 0.0363 0.2531 0.2659
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0253 0.1726 0.2005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0363 0.2531 0.2659
Onchocerca volvulus 0.0034 0.0115 0.0254
Schistosoma mansoni glutamate receptor NMDA 0.0269 0.1842 0.1935
Schistosoma mansoni biogenic amine receptor 0.0363 0.2531 0.2659
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0363 0.2531 0.2939
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0054 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Brugia malayi PDZ domain containing protein 0.0051 0.0235 0.0273
Echinococcus multilocularis disks large 3 0.0023 0.0035 0.0035
Brugia malayi Furin-like cysteine rich region family protein 0.0144 0.0921 0.107
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0055 0.0266 0.5716
Schistosoma mansoni ephrin receptor 0.019 0.1264 0.1327
Toxoplasma gondii subtilisin SUB10 0.0055 0.0266 0.0481
Schistosoma mansoni neuropeptide receptor 0.0363 0.2531 0.2659
Echinococcus multilocularis g protein coupled receptor 0.0363 0.2531 0.2531
Echinococcus multilocularis rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Echinococcus multilocularis 0.0942 0.679 0.679
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.016 0.0159
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0054 0.0054
Echinococcus multilocularis guanylate kinase 0.0019 0.0006 0.0006
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.014 0.089 0.1034
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0113 0.0696 0.125
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0054 0.0056
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0034 0.0113 0.0112
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0363 0.2531 0.2939
Schistosoma mansoni opsin-like receptor 0.0363 0.2531 0.2659
Echinococcus granulosus tyrosine kinase 0.002 0.0006 0.0006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Loa Loa (eye worm) TK protein kinase 0.0037 0.0132 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1086 0.1956
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0054 0.0054
Echinococcus multilocularis allatostatin A receptor 0.0634 0.4528 0.4528
Echinococcus granulosus tyrosine kinase 0.0037 0.0132 0.0132
Onchocerca volvulus 0.0019 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.003 0.0086 0.0191
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0034 0.0113 0.0112
Trypanosoma brucei C-8 sterol isomerase, putative 0.0361 0.252 0.4554
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Echinococcus multilocularis g protein coupled receptor 0.0363 0.2531 0.2531
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0048 0.0218 0.0218
Brugia malayi putative neuropeptide receptor 0.0363 0.2531 0.2939
Schistosoma mansoni hypothetical protein 0.014 0.089 0.0935
Schistosoma mansoni neuropeptide receptor 0.0363 0.2531 0.2659
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Echinococcus granulosus tyrosine protein kinase Src64B 0.004 0.016 0.0159
Loa Loa (eye worm) tubulin beta chain 0.077 0.5527 0.6418
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0054 0.0054
Loa Loa (eye worm) lethal(1)discs large-1 tumor suppressor 0.0019 0.0006 0.0007
Loa Loa (eye worm) RGC/RGC protein kinase 0.002 0.0006 0.0007
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0734 0.5262 0.952
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1086 0.1956
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0054 0.0062
Echinococcus multilocularis dro:myosuppressin receptor 0.0363 0.2531 0.2531
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1151 0.2075
Schistosoma mansoni glutamate receptor AMPA 0.0032 0.0098 0.0102
Onchocerca volvulus 0.0019 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0363 0.2531 0.2659
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0054 0.0062
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Onchocerca volvulus Neuropeptide F receptor homolog 0.0363 0.2531 0.559
Echinococcus granulosus G protein coupled receptor 139 0.0363 0.2531 0.2531
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0363 0.2531 0.2659
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Loa Loa (eye worm) TK/EPH protein kinase 0.0242 0.1641 0.1906
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.0049 0.0226 0.0226
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0363 0.2531 0.2531
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.0049 0.0226 0.0226
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1086 0.1956
Echinococcus granulosus beta tubulin 0.077 0.5527 0.5527
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0054 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0054 0.0062
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0054 0.0054
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0082 0.0465 0.5
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0048 0.0218 0.0218
Echinococcus multilocularis orexin receptor type 2 0.0363 0.2531 0.2531
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0033 0.0109 0.0109
Echinococcus granulosus sex peptide receptor 0.0363 0.2531 0.2531
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.1086 0.2398
Schistosoma mansoni hypothetical protein 0.0363 0.2531 0.2659
Echinococcus multilocularis neuropeptides capa receptor 0.0363 0.2531 0.2531
Brugia malayi Shank2E 0.0019 0.0001 0.0001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0051 0.0235 0.0273
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0303 0.2088 0.2194
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0363 0.2531 0.2939
Brugia malayi ZU5 domain containing protein 0.0019 0.0006 0.0007
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0054 0.0054
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0055 0.0266 0.5716
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0113 0.0696 0.125
Echinococcus granulosus rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Onchocerca volvulus 0.0363 0.2531 0.559
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0164 0.1071 0.1243
Echinococcus granulosus neuropeptide receptor 0.0363 0.2531 0.2531
Echinococcus granulosus MAM 0.0023 0.0034 0.0034
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0363 0.2531 0.2659
Echinococcus granulosus somatostatin receptor 0.0363 0.2531 0.2531
Giardia lamblia Furin precursor putative serine protease 0.0248 0.1685 0.3042
Chlamydia trachomatis glutamine binding protein 0.0082 0.0465 1
Echinococcus granulosus glutamate receptor 2 0.0048 0.0218 0.0218
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0164 0.1071 0.1243
Brugia malayi larval opioid receptor 0.0363 0.2531 0.2939
Loa Loa (eye worm) hypothetical protein 0.014 0.089 0.1034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Brugia malayi map kinase activated protein kinase protein 2 0.0174 0.1146 0.1331
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0363 0.2531 0.2531
Schistosoma mansoni adenoreceptor 0.0363 0.2531 0.2659
Loa Loa (eye worm) RGC/RGC protein kinase 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus granulosus allatostatin A receptor 0.0634 0.4528 0.4528
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Loa Loa (eye worm) BEN-1 protein 0.077 0.5527 0.6418
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0054 0.0054
Echinococcus granulosus glutamate receptor subunit protein glur 0.0032 0.0098 0.0097
Leishmania major beta tubulin 0.077 0.5527 1
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Schistosoma mansoni tubulin subunit beta 0.077 0.5527 0.5807
Echinococcus multilocularis Tubulin beta 2C chain 0.077 0.5527 0.5527
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0082 0.0465 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Entamoeba histolytica protein kinase, putative 0.0033 0.0104 0.0178
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0023 0.0035 0.0035
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Echinococcus multilocularis g-protein coupled receptor 0.0363 0.2531 0.2531
Loa Loa (eye worm) tubulin beta-1 chain 0.077 0.5527 0.6418
Echinococcus multilocularis somatostatin receptor 0.0363 0.2531 0.2531
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0113 0.0696 0.125
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Brugia malayi steroid hormone receptor 0.0026 0.0054 0.0062
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0363 0.2531 0.2939
Echinococcus multilocularis rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Brugia malayi Guanylate kinase family protein 0.0019 0.0006 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0363 0.2531 0.2531
Brugia malayi G protein-coupled receptor F59B2.13 0.0363 0.2531 0.2939
Trichomonas vaginalis tubulin epsilon chain, putative 0.077 0.5527 1
Onchocerca volvulus 0.0077 0.0429 0.0948
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0054 0.0054
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0098 0.0102
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0248 0.1685 0.3042
Toxoplasma gondii subtilisin SUB1 0.0055 0.0266 0.0481
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0734 0.5262 0.952
Echinococcus granulosus neuropeptide receptor 0.0363 0.2531 0.2531
Echinococcus granulosus 7TM GPCR rhodopsin 0.0363 0.2531 0.2531
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.014 0.089 0.089
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0324 0.0324
Loa Loa (eye worm) glutamate receptor 1 0.0032 0.0098 0.0113
Schistosoma mansoni maguk P55 subfamily member 26 0.0023 0.0035 0.0037
Schistosoma mansoni septate junction protein 0.0023 0.0033 0.0035
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0303 0.2088 0.3771
Toxoplasma gondii PAN domain-containing protein 0.0289 0.1992 0.3604
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.0696 0.125
Echinococcus multilocularis high voltage activated calcium channel beta 0.0019 0.0006 0.0006
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0055 0.0266 0.0265
Echinococcus granulosus Tubulin beta 2C chain 0.077 0.5527 0.5527
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1151 0.2075
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus granulosus neuropeptide receptor A26 0.0363 0.2531 0.2531
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0032 0.0098 0.0097
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0363 0.2531 0.2659
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0048 0.0218 0.0218
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0054 0.0054
Schistosoma mansoni hypothetical protein 0.0101 0.0609 0.064
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0082 0.0465 1
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0066 0.0345 0.0614
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0187 0.124 0.144
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0023 0.0035 0.0041
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0054 0.0056
Toxoplasma gondii subtilisin SUB11 0.0055 0.0266 0.0481
Loa Loa (eye worm) G-protein coupled receptor 0.0363 0.2531 0.2939
Echinococcus multilocularis high voltage activated calcium channel beta 0.0019 0.0006 0.0006
Toxoplasma gondii subtilisin SUB5 0.0055 0.0266 0.0481
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0054 0.0062
Brugia malayi proprotein convertase 2 0.0758 0.5438 0.6315
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0363 0.2531 0.2531
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Brugia malayi neuropeptide F receptor 0.0363 0.2531 0.2939
Schistosoma mansoni myosin xvIII 0.0363 0.2531 0.2659
Schistosoma mansoni tyrosine kinase 0.004 0.016 0.0168
Brugia malayi Guanylate kinase family protein 0.0027 0.0063 0.0073
Schistosoma mansoni hypothetical protein 0.014 0.089 0.0935
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Brugia malayi beta-tubulin, identical 0.077 0.5527 0.6418
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis disks large 1 0.0019 0.0006 0.0006
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0082 0.0465 0.5
Trypanosoma brucei RNA helicase, putative 0.0314 0.217 0.3921
Loa Loa (eye worm) hypothetical protein 0.0101 0.0609 0.0708
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Leishmania major beta tubulin 0.077 0.5527 1
Brugia malayi Dopamine receptor protein 2 0.0363 0.2531 0.2939
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0034 0.0113 0.0193
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0363 0.2531 0.2659
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0363 0.2531 0.2531
Brugia malayi replication factor A 73 kDa subunit 0.0034 0.0113 0.0131
Giardia lamblia High cysteine membrane protein Group 2 0.0432 0.3037 0.549
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0363 0.2531 0.2939
Onchocerca volvulus 0.002 0.0006 0.0014
Echinococcus granulosus high voltage activated calcium channel beta 0.0019 0.0006 0.0006
Echinococcus multilocularis membrane bound transcription factor site 1 0.0055 0.0266 0.0265
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.004 0.016 0.0159
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0363 0.2531 0.2531
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0066 0.0345 0.0614
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0363 0.2531 0.2531
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0363 0.2531 0.2659
Mycobacterium leprae Possible secreted protease 0.0055 0.0266 1
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0098 0.0102
Plasmodium falciparum tubulin beta chain 0.077 0.5527 1
Toxoplasma gondii subtilisin SUB9 0.0055 0.0266 0.0481
Onchocerca volvulus 0.0363 0.2531 0.559
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0054 0.0062
Schistosoma mansoni high voltage-activated calcium channel beta subunit 1 0.0019 0.0006 0.0006
Schistosoma mansoni tubulin subunit beta 0.077 0.5527 0.5807
Brugia malayi Dopamine receptor protein 1 0.0363 0.2531 0.2939
Echinococcus granulosus guanylate kinase 0.0019 0.0006 0.0006
Schistosoma mansoni glutamate receptor AMPA 0.0032 0.0098 0.0102
Echinococcus granulosus nmda type glutamate receptor 0.0114 0.0699 0.0699
Trichomonas vaginalis conserved hypothetical protein 0.0248 0.1685 0.3042
Entamoeba histolytica hypothetical protein 0.0038 0.0145 0.0251
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0062
Echinococcus multilocularis glutamate receptor 2 0.0048 0.0218 0.0218
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Echinococcus granulosus neuropeptides capa receptor 0.0363 0.2531 0.2531
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0048 0.0218 0.0218
Echinococcus granulosus tm gpcr rhodopsin 0.0363 0.2531 0.2531
Echinococcus granulosus rhodopsin orphan GPCR 0.0363 0.2531 0.2531
Loa Loa (eye worm) tubulin beta-4 chain 0.077 0.5527 0.6418
Toxoplasma gondii subtilisin SUB2 0.0055 0.0266 0.0481
Schistosoma mansoni biogenic amine (5HT) receptor 0.0363 0.2531 0.2659
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0363 0.2531 0.2939
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0248 0.1685 0.3042
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Brugia malayi Dopamine receptor 0.0363 0.2531 0.2939
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0363 0.2531 0.2659
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0054 0.0056
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0324 0.0377
Echinococcus multilocularis glutamate receptor 2 0.0032 0.0098 0.0097
Echinococcus multilocularis serotonin receptor 0.0363 0.2531 0.2531
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.016 0.0159
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.004
Schistosoma mansoni biogenic amine receptor 0.0363 0.2531 0.2659
Brugia malayi putative neuropeptide receptor NPR1 0.0363 0.2531 0.2939
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Schistosoma mansoni furin-1 (S08 family) 0.051 0.3616 0.3799
Schistosoma mansoni alpha-1 adrenergic receptor 0.0363 0.2531 0.2659
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1086 0.1956
Echinococcus granulosus neuropeptide FF receptor 2 0.0813 0.5844 0.5843
Schistosoma mansoni tyrosine kinase 0.002 0.0006 0.0007
Trichomonas vaginalis tubulin gamma chain, putative 0.077 0.5527 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0054 0.0056
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.016 0.0159
Onchocerca volvulus 0.0055 0.0266 0.0587
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0054 0.0062
Echinococcus multilocularis GPCR, family 2 0.0063 0.0324 0.0324
Schistosoma mansoni amine GPCR 0.0363 0.2531 0.2659
Echinococcus granulosus ephrin type A receptor 4 A 0.019 0.1264 0.1263
Trypanosoma brucei calpain, putative 0.0113 0.0696 0.125
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0113 0.0696 0.125
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0363 0.2531 0.2659
Onchocerca volvulus 0.0023 0.0034 0.0076
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0113 0.0696 0.125
Onchocerca volvulus 0.0026 0.0054 0.0119
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0734 0.5262 0.5262
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.1726 0.3116
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0609 0.0708
Leishmania major beta tubulin 0.077 0.5527 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.004 0.016 0.0159
Echinococcus multilocularis ephrin type A receptor 4 A 0.019 0.1264 0.1263
Schistosoma mansoni ATP-dependent RNA Helicase 0.0023 0.0035 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0363 0.2531 0.2659
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0363 0.2531 0.2531
Echinococcus multilocularis serotonin receptor 0.0363 0.2531 0.2531
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0082 0.0465 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Schistosoma mansoni mannosidase endo-alpha 0.0019 0.0006 0.0006
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0113 0.0696 0.125
Plasmodium vivax subtilisin-like protease 1 0.0055 0.0266 0.047
Brugia malayi Calcitonin receptor-like protein seb-1 0.0164 0.1071 0.1243
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0734 0.5262 0.5262
Loa Loa (eye worm) guanylate kinase 0.0019 0.0006 0.0007
Leishmania major beta tubulin 0.077 0.5527 1
Loa Loa (eye worm) neuropeptide F receptor 0.0363 0.2531 0.2939
Schistosoma mansoni serine-type protease inhibitor 0.1313 0.9517 1
Loa Loa (eye worm) beta-tubulin 0.077 0.5527 0.6418
Brugia malayi hypothetical protein 0.0038 0.0145 0.0168
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0054 0.0056
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Brugia malayi RE15519p 0.0363 0.2531 0.2939
Echinococcus granulosus tm gpcr rhodopsin 0.0363 0.2531 0.2531
Schistosoma mansoni tubulin subunit beta 0.077 0.5527 0.5807
Brugia malayi hypothetical protein 0.0363 0.2531 0.2939
Toxoplasma gondii beta-1 tubulin, putative 0.077 0.5527 1
Onchocerca volvulus 0.0363 0.2531 0.559
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0054 0.0054
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0634 0.4528 0.4757
Schistosoma mansoni hypothetical protein 0.0363 0.2531 0.2659
Entamoeba histolytica hypothetical protein 0.0038 0.0145 0.0251
Toxoplasma gondii guanylate kinase family protein 0.0019 0.0006 0.0011
Echinococcus multilocularis neuropeptide Y receptor 0.0363 0.2531 0.2531
Schistosoma mansoni hypothetical protein 0.0063 0.0324 0.034
Toxoplasma gondii beta-tubulin, putative 0.077 0.5527 1
Trypanosoma brucei beta tubulin 0.077 0.5527 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0054 0.0062
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Echinococcus multilocularis MAM 0.0023 0.0034 0.0034
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0303 0.2088 0.3771
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.004 0.016 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0054 0.0062
Loa Loa (eye worm) G-protein coupled receptor 0.0363 0.2531 0.2939
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0324 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0266 0.047
Brugia malayi Protein kinase domain containing protein 0.0026 0.0057 0.0067
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.0054 0.0119
Trypanosoma brucei beta tubulin 0.077 0.5527 1
Brugia malayi guanylate kinase 0.0019 0.0006 0.0007
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0054 0.0062
Loa Loa (eye worm) hypothetical protein 0.0363 0.2531 0.2939
Leishmania major subtilisin-like serine peptidase 0.0055 0.0266 0.047
Schistosoma mansoni tyrosine kinase 0.0144 0.0921 0.0968
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0054 0.0062
Schistosoma mansoni neuropeptide receptor 0.0363 0.2531 0.2659
Brugia malayi Peripheral plasma membrane protein CASK 0.0027 0.0063 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0054 0.0062
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.016 0.0159
Echinococcus granulosus g protein coupled receptor 0.0363 0.2531 0.2531
Echinococcus granulosus neuropeptide s receptor 0.0363 0.2531 0.2531
Leishmania major beta tubulin 0.077 0.5527 1
Onchocerca volvulus 0.0363 0.2531 0.559
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.016 0.0159
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.004 0.016 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0054 0.0062
Brugia malayi G-protein coupled receptor 0.0363 0.2531 0.2939
Echinococcus granulosus dro:myosuppressin receptor 0.0363 0.2531 0.2531
Plasmodium vivax subtilisin-like protease 2, putative 0.0055 0.0266 0.047
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0174 0.1146 0.1146
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0023 0.0035 0.0035
Echinococcus granulosus neuroendocrine convertase 2 0.0758 0.5438 0.5438
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0363 0.2531 0.2531
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0266 0.047
Toxoplasma gondii subtilisin SUB6 0.0055 0.0266 0.0481
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0055 0.0266 0.5663
Schistosoma mansoni amine GPCR 0.0363 0.2531 0.2659
Loa Loa (eye worm) hypothetical protein 0.0029 0.0076 0.0088
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.119 0.8612 0.9049
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0363 0.2531 0.2531

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = -21 % Allosteric enhancer activity at recombinant human A1 adenosine receptor expressed in CHO cells assessed as change in forskolin-induced cAMP production at 10 uM after 6 mins by radioimmunoassay ChEMBL. 22182575
Activity (functional) = 0 % Allosteric enhancer activity at recombinant human A1 adenosine receptor expressed in CHO cells assessed as change in forskolin-induced cAMP production at 0.1 uM after 6 mins by radioimmunoassay ChEMBL. 22182575
Activity (functional) = 2.9 % Allosteric enhancer activity at recombinant human A1 adenosine receptor expressed in CHO cells assessed as change in forskolin-induced cAMP production at 1 uM after 6 mins by radioimmunoassay ChEMBL. 22182575
Activity (functional) = 8.7 % Allosteric enhancer activity at recombinant human A1 adenosine receptor expressed in CHO cells assessed as change in forskolin-induced cAMP production at 0.01 uM after 6 mins by radioimmunoassay ChEMBL. 22182575
Inhibition (binding) = 0 % Displacement of [3H]MRE3008F20 from recombinant human A3 adenosine receptor expressed in CHO cells at 10 uM after 120 mins by scintillation counting ChEMBL. 22182575
Inhibition (binding) = 0 % Displacement of [3H]ZM241385 from recombinant human A2A adenosine receptor expressed in CHO cells at 10 uM after 60 mins by scintillation counting ChEMBL. 22182575
Inhibition (binding) = 1 % Displacement of [3H]DPCPX from recombinant human A1 adenosine receptor expressed in CHO cells at 10 uM after 120 mins by scintillation counting ChEMBL. 22182575

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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