TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 272.751 | Formula: C11H13ClN2O2S
H donors: 1 H acceptors: 2 LogP: 2.31 Rotable bonds: 0
Rule of 5 violations (Lipinski): 1
SMILES: Clc1cc2[C@@H](C)CN3c2c(c1)S(=O)(=O)NC3C
InChi: 1S/C11H13ClN2O2S/c1-6-5-14-7(2)13-17(15,16)10-4-8(12)3-9(6)11(10)14/h3-4,6-7,13H,5H2,1-2H3/t6-,7?/m0/s1
InChiKey: KSKGRNZBDPHWLY-PKPIPKONSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	sex peptide receptor	0.0108	0.9071	1
Mycobacterium tuberculosis	Diaminopimelate decarboxylase LysA (DAP decarboxylase)	0.0059	0.4269	0.5
Mycobacterium leprae	PROBABLE DIAMINOPIMELATE DECARBOXYLASE LYSA (DAP DECARBOXYLASE)	0.0023	0.0681	0.5
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Loa Loa (eye worm)	MH2 domain-containing protein	0.0118	1	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0108	0.9071	1
Trichomonas vaginalis	diaminopimelate decarboxylase, putative	0.0059	0.4269	1
Onchocerca volvulus		0.0108	0.9071	1
Schistosoma mansoni	amine GPCR	0.0108	0.9071	1
Schistosoma mansoni	amine GPCR	0.0108	0.9071	1
Echinococcus granulosus	neuropeptide receptor	0.0108	0.9071	1
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0108	0.9071	1
Brugia malayi	FAD binding domain containing protein	0.0026	0.0975	0.0975
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0108	0.9071	1
Trichomonas vaginalis	conserved hypothetical protein	0.0023	0.0681	0.0446
Echinococcus granulosus	g protein coupled receptor	0.0108	0.9071	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0108	0.9071	1
Schistosoma mansoni	neuropeptide receptor	0.0108	0.9071	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0108	0.9071	1
Trypanosoma cruzi	cytochrome P450 reductase, putative	0.0026	0.0975	0.5
Echinococcus multilocularis	NADPH cytochrome P450 reductase	0.0026	0.0975	0.1074
Loa Loa (eye worm)	G-protein coupled receptor	0.0108	0.9071	0.9071
Brugia malayi	follicle stimulating hormone receptor	0.0108	0.9071	0.9071
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0108	0.9071	1
Brugia malayi	putative neuropeptide receptor NPR1	0.0108	0.9071	0.9071
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0108	0.9071	1
Echinococcus multilocularis	dro:myosuppressin receptor	0.0108	0.9071	1
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0108	0.9071	1
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0975	0.0975
Brugia malayi	larval opioid receptor	0.0108	0.9071	0.9071
Echinococcus granulosus	rhodopsin orphan GPCR	0.0108	0.9071	1
Brugia malayi	putative neuropeptide receptor	0.0108	0.9071	0.9071
Schistosoma mansoni	myosin xvIII	0.0108	0.9071	1
Entamoeba histolytica	ornithine decarboxylase, putative	0.0059	0.4269	0.5
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0108	0.9071	0.9071
Trypanosoma brucei	ornithine decarboxylase	0.0059	0.4269	1
Onchocerca volvulus		0.0108	0.9071	1
Trichomonas vaginalis	ornithine decarboxylase, putative	0.0059	0.4269	1
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0108	0.9071	1
Echinococcus granulosus	neuropeptide Y receptor	0.0108	0.9071	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0108	0.9071	1
Echinococcus granulosus	neuropeptide receptor	0.0108	0.9071	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	tm gpcr rhodopsin	0.0108	0.9071	1
Schistosoma mansoni	biogenic amine receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Giardia lamblia	Ornithine decarboxylase	0.0059	0.4269	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0108	0.9071	1
Echinococcus granulosus	neuropeptide receptor A26	0.0108	0.9071	1
Echinococcus multilocularis	neuropeptide receptor	0.0108	0.9071	1
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	biogenic amine 5HT receptor	0.0108	0.9071	1
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0108	0.9071	1
Echinococcus multilocularis	serotonin receptor	0.0108	0.9071	1
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0108	0.9071	0.9071
Brugia malayi	GnHR receptor homolog	0.0108	0.9071	0.9071
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0108	0.9071	1
Brugia malayi	Serotonin receptor	0.0108	0.9071	0.9071
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Schistosoma mansoni	growth hormone secretagogue receptor	0.0108	0.9071	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Plasmodium vivax	S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative	0.0059	0.4269	1
Leishmania major	p450 reductase, putative	0.0026	0.0975	0.0808
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0108	0.9071	1
Brugia malayi	Pyridoxal-dependent decarboxylase, pyridoxal binding domain containing protein	0.0059	0.4269	0.4269
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	neuropeptide Y receptor	0.0108	0.9071	1
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0108	0.9071	1
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0108	0.9071	1
Echinococcus granulosus	somatostatin receptor	0.0108	0.9071	1
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0108	0.9071	1
Echinococcus granulosus	neuropeptides capa receptor	0.0108	0.9071	1
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Onchocerca volvulus		0.0108	0.9071	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0108	0.9071	1
Brugia malayi	neuropeptide F receptor	0.0108	0.9071	0.9071
Chlamydia trachomatis	sulfite reductase	0.0016	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	sex peptide receptor	0.0108	0.9071	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0108	0.9071	1
Schistosoma mansoni	neuropeptide receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Schistosoma mansoni	neuropeptide F-like receptor	0.0108	0.9071	1
Schistosoma mansoni	biogenic amine receptor	0.0108	0.9071	1
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0108	0.9071	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0108	0.9071	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0108	0.9071	1
Trichomonas vaginalis	diaminopimelate decarboxylase, putative	0.0059	0.4269	1
Echinococcus granulosus	neuropeptides capa receptor	0.0108	0.9071	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0108	0.9071	1
Echinococcus multilocularis	g protein coupled receptor	0.0108	0.9071	1
Schistosoma mansoni	amine GPCR	0.0108	0.9071	1
Plasmodium falciparum	S-adenosylmethionine decarboxylase/ornithine decarboxylase	0.0059	0.4269	1
Brugia malayi	G-protein coupled receptor	0.0108	0.9071	0.9071
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0108	0.9071	1
Brugia malayi	ORL1-like opioid receptor	0.0108	0.9071	0.9071
Echinococcus granulosus	7TM GPCR rhodopsin	0.0108	0.9071	1
Echinococcus multilocularis	orexin receptor type 2	0.0108	0.9071	1
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0108	0.9071	0.9071
Trichomonas vaginalis	ornithine decarboxylase, putative	0.0059	0.4269	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0108	0.9071	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0108	0.9071	1
Echinococcus multilocularis	NADPH dependent diflavin oxidoreductase 1	0.0026	0.0975	0.1074
Brugia malayi	neuropeptide F receptor	0.0108	0.9071	0.9071
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0108	0.9071	1
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0108	0.9071	1
Trypanosoma cruzi	NADPH-dependent FMN/FAD containing oxidoreductase, putative	0.0026	0.0975	0.5
Brugia malayi	RE15519p	0.0108	0.9071	0.9071
Schistosoma mansoni	hypothetical protein	0.0108	0.9071	1
Echinococcus granulosus	hypothetical protein	0.0108	0.9071	1
Echinococcus multilocularis	G protein coupled receptor 139	0.0108	0.9071	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0108	0.9071	1
Loa Loa (eye worm)	melatonin receptor type 1A	0.0108	0.9071	0.9071
Echinococcus granulosus	tm gpcr rhodopsin	0.0108	0.9071	1
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0108	0.9071	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus multilocularis	fmrfamide receptor	0.0108	0.9071	1
Echinococcus multilocularis	g protein coupled receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus multilocularis	g protein coupled receptor	0.0108	0.9071	1
Brugia malayi	Dopamine receptor	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	NADPH dependent diflavin oxidoreductase 1	0.0026	0.0975	0.1074
Schistosoma mansoni	amine GPCR	0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Loa Loa (eye worm)	FAD binding domain-containing protein	0.0026	0.0975	0.0975
Echinococcus multilocularis	neuropeptides capa receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	rhodopsin orphan GPCR	0.0108	0.9071	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Mycobacterium ulcerans	diaminopimelate decarboxylase LysA	0.0059	0.4269	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0108	0.9071	1
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0108	0.9071	1
Echinococcus granulosus	g protein coupled receptor	0.0108	0.9071	1
Schistosoma mansoni	neuropeptide receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus multilocularis	neuropeptide receptor A26	0.0108	0.9071	1
Brugia malayi	Dopamine receptor protein 2	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	serotonin receptor	0.0108	0.9071	1
Leishmania major	ornithine decarboxylase, putative	0.0059	0.4269	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0108	0.9071	1
Brugia malayi	AKH receptor	0.0108	0.9071	0.9071
Echinococcus multilocularis	somatostatin receptor	0.0108	0.9071	1
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Trichomonas vaginalis	pyridoxal-dependent decarboxylase, putative	0.0059	0.4269	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Onchocerca volvulus		0.0108	0.9071	1
Brugia malayi	flavodoxin family protein	0.0026	0.0975	0.0975
Brugia malayi	G-protein coupled receptor	0.0108	0.9071	0.9071
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0108	0.9071	1
Echinococcus granulosus	orexin receptor type 2	0.0108	0.9071	1
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0108	0.9071	1
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0108	0.9071	1
Brugia malayi	Serotonin receptor	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	neuropeptide F receptor	0.0108	0.9071	0.9071
Echinococcus granulosus	neuropeptide s receptor	0.0108	0.9071	1
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0108	0.9071	1
Leishmania major	NADPH-cytochrome p450 reductase-like protein	0.0026	0.0975	0.0808
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	g-protein coupled receptor	0.0108	0.9071	1
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Onchocerca volvulus		0.0108	0.9071	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0108	0.9071	1
Schistosoma mansoni	opsin-like receptor	0.0108	0.9071	1
Echinococcus granulosus	G protein coupled receptor 139	0.0108	0.9071	1
Schistosoma mansoni	hypothetical protein	0.0108	0.9071	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0108	0.9071	1
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0108	0.9071	1
Brugia malayi	G protein-coupled receptor	0.0108	0.9071	0.9071
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus multilocularis	allatostatin A receptor	0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Schistosoma mansoni	histamine h1 receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus multilocularis	neuropeptide Y receptor	0.0108	0.9071	1
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Loa Loa (eye worm)	transcription factor SMAD2	0.0118	1	1
Schistosoma mansoni	hypothetical protein	0.0108	0.9071	1
Schistosoma mansoni	amine GPCR	0.0108	0.9071	1
Echinococcus granulosus	NADPH cytochrome P450 reductase	0.0026	0.0975	0.1074
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0108	0.9071	1
Toxoplasma gondii	diaminopimelate decarboxylase	0.0059	0.4269	0.5
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	neuropeptide FF receptor 2	0.0108	0.9071	1
Echinococcus multilocularis	fmrfamide receptor	0.0108	0.9071	1
Echinococcus multilocularis	neuropeptide receptor	0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0108	0.9071	0.9071
Loa Loa (eye worm)	pyridoxal-dependent decarboxylase	0.0059	0.4269	0.4269
Loa Loa (eye worm)	TYRA-2 protein	0.0108	0.9071	0.9071
Echinococcus multilocularis	neuropeptides capa receptor	0.0108	0.9071	1
Schistosoma mansoni	opsin-like receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	rhodopsin orphan GPCR	0.0108	0.9071	1
Schistosoma mansoni	neuropeptide receptor	0.0108	0.9071	1
Schistosoma mansoni	hypothetical protein	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	fmrfamide receptor	0.0108	0.9071	1
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0108	0.9071	1
Echinococcus granulosus	allatostatin A receptor	0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0108	0.9071	0.9071
Trichomonas vaginalis	NADPH fad oxidoreductase, putative	0.0023	0.0685	0.0457
Echinococcus granulosus	g protein coupled receptor	0.0108	0.9071	1
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0108	0.9071	1
Brugia malayi	Melatonin receptor type 1A	0.0108	0.9071	0.9071
Brugia malayi	G protein-coupled receptor F59B2.13	0.0108	0.9071	0.9071
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0108	0.9071	0.9071
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0108	0.9071	1
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0108	0.9071	0.9071
Echinococcus multilocularis	neuropeptide Y receptor	0.0108	0.9071	1
Onchocerca volvulus		0.0108	0.9071	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0108	0.9071	1
Trichomonas vaginalis	sulfite reductase, putative	0.0026	0.0975	0.1228
Schistosoma mansoni	opsin-like receptor	0.0108	0.9071	1
Echinococcus multilocularis	serotonin receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Trypanosoma cruzi	cytochrome P450 reductase, putative	0.0026	0.0975	0.5
Echinococcus granulosus	7tm_1 domain containing protein	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Schistosoma mansoni	adenoreceptor	0.0108	0.9071	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0108	0.9071	1
Plasmodium vivax	NADPH-cytochrome p450 reductase, putative	0.0026	0.0975	0.0808
Onchocerca volvulus		0.0108	0.9071	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0108	0.9071	1
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0108	0.9071	0.9071
Trypanosoma cruzi	p450 reductase, putative	0.0026	0.0975	0.5
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0108	0.9071	0.9071
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0108	0.9071	0.9071
Echinococcus multilocularis	neuropeptide s receptor	0.0108	0.9071	1
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0108	0.9071	0.9071
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0108	0.9071	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0108	0.9071	1
Echinococcus granulosus	dro:myosuppressin receptor	0.0108	0.9071	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0108	0.9071	1
Schistosoma mansoni	cytochrome P450 reductase	0.0026	0.0975	0.1074
Echinococcus multilocularis	g-protein coupled receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Brugia malayi	sulfakinin receptor protein	0.0108	0.9071	0.9071
Schistosoma mansoni	neuropeptide f receptor 76f	0.0108	0.9071	1
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	biogenic amine 5HT receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0108	0.9071	1
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0108	0.9071	1
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Loa Loa (eye worm)	hypothetical protein	0.0108	0.9071	0.9071
Brugia malayi	Dopamine receptor protein 1	0.0108	0.9071	0.9071
Brugia malayi	hypothetical protein	0.0108	0.9071	0.9071
Schistosoma mansoni	biogenic amine receptor	0.0108	0.9071	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1929397

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1600772