Detailed information for compound 16018

Basic information

Technical information
  • TDR Targets ID: 16018
  • Name: benzene
  • MW: 78.1118 | Formula: C6H6
  • H donors: 0 H acceptors: 0 LogP: 1.92 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccccc1
  • InChi: 1S/C6H6/c1-2-4-6-5-3-1/h1-6H
  • InChiKey: UHOVQNZJYSORNB-UHFFFAOYSA-N  

Network

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Synonyms

  • naphtha
  • ligroin
  • Petroleum
  • asphalt
  • rubber solvent
  • Stoddard solvent
  • acodazole
  • Coal Tar
  • 27271-55-2
  • 68956-52-5
  • 26181-88-4
  • 174973-66-1
  • 54682-86-9
  • 71-43-2
  • NCGC00090744-02
  • UN1114
  • Benzen [Polish]
  • Benzene + aniline combo
  • 270709_ALDRICH
  • 311855_SIGMA
  • Benzene (including benzene from gasoline)
  • 676985_ALDRICH
  • Benzene [UN1114] [Flammable liquid]
  • 154628_SIAL
  • Benzene, labeled with carbon-14 and tritium
  • benzol
  • benzole
  • 322644_SIGMA
  • Benzin (Obs.)
  • InChI=1/C6H6/c1-2-4-6-5-3-1/h1-6
  • 12540_FLUKA
  • Benzine (Obs.)
  • NCGC00163890-02
  • Benzol 90
  • Benzene-U-14C
  • NCGC00090744-01
  • Benzene-UL-14C
  • 401765_ALDRICH
  • Benzol diluent
  • 12552_FLUKA
  • Benzolo [Italian]
  • RNG
  • 12553_FLUKA
  • 319953_SIAL
  • ST5214351
  • CHEBI:16716
  • NCGC00163890-01
  • ghl.PD_Mitscher_leg0.503
  • Benzene, pure
  • BNZ
  • c0142
  • Hydrocarbons, C4-8
  • Benzeen
  • Benzen
  • Benzin
  • Benzine
  • Benzolene
  • Benzolo
  • Bicarburet of hydrogen
  • Carbon oil
  • Coal naphtha
  • Cyclohexatriene
  • Fenzen
  • Mineral naphtha
  • Motor benzol
  • NCI-C55276
  • NSC67315
  • Nitration benzene
  • Phenyl hydride
  • Pyrobenzol
  • Pyrobenzole
  • WLN: RH
  • [6]Annulene
  • CCRIS 70
  • Caswell No. 077
  • EINECS 200-753-7
  • EPA Pesticide Chemical Code 008801
  • Fenzen [Czech]
  • HSDB 35
  • NSC 67315
  • Phene
  • Aromatic alkane
  • RCRA waste no. U109
  • RCRA waste number U019
  • UN 1114
  • Polystream
  • C01407
  • (6)Annulene
  • 32212_RIEDEL
  • Benzene, labeled with carbon-14
  • 48503_SUPELCO
  • AI3-00808
  • Benzeen [Dutch]

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0056 0.0061
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0004
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0268 0.1704 0.1872
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Loa Loa (eye worm) DR-78 0.0071 0.0374 0.0374
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0042 0.0046
Trypanosoma brucei proteasome subunit beta type-5, putative 0.1362 0.9102 0.9102
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0181 0.0198
Leishmania major proteasome alpha 1 subunit, putative 0.0268 0.1704 0.1704
Brugia malayi Tachykinin-like peptides receptor 99D 0.0078 0.042 0.042
Toxoplasma gondii NAC domain-containing protein 0.0036 0.0138 0.0146
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0028 0.0028
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0043 0.0042
Onchocerca volvulus 0.0078 0.042 0.152
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0078 0.042 0.042
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Schistosoma mansoni neuropeptide F-like receptor 0.0078 0.042 0.0462
Brugia malayi neuropeptide F receptor 0.0078 0.042 0.042
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0042 0.0046
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0268 0.1704 0.1872
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0215 0.1347 0.1347
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0268 0.1704 0.1836
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0135 0.0148
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0268 0.1704 0.1872
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0079 0.0432 0.0475
Loa Loa (eye worm) hypothetical protein 0.015 0.0911 0.0911
Mycobacterium leprae Probable lipase LipE 0.0037 0.0146 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-14 0.015 0.0911 0.0911
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0042 0.0046
Brugia malayi Dopamine receptor 0.0078 0.042 0.042
Brugia malayi PXA domain containing protein 0.002 0.0028 0.0028
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0146 0.0154
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0095 0.0105
Brugia malayi G protein-coupled receptor F59B2.13 0.0078 0.042 0.042
Echinococcus granulosus sex peptide receptor 0.0078 0.042 0.0462
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0042 0.0046
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0268 0.1704 0.1704
Loa Loa (eye worm) proteasome subunit beta type 3 0.0268 0.1704 0.1704
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Toxoplasma gondii proteasome beta subunit 0.0268 0.1704 0.1868
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0421 0.2739 0.2739
Loa Loa (eye worm) hypothetical protein 0.0042 0.0181 0.0181
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0268 0.1704 0.1704
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0005 0.0005
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0078 0.042 0.0462
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0104 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0028 0.0031
Brugia malayi Steroid receptor seven-up type 2 0.015 0.0911 0.0911
Trypanosoma brucei C-8 sterol isomerase, putative 0.1495 1 1
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.0138 0.0146
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0068 0.0354 0.0354
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.015 0.0911 0.1001
Brugia malayi isocitrate dehydrogenase 0.0016 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.042 0.0462
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0028 0.0031
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0043 0.0043
Trypanosoma brucei C-14 sterol reductase, putative 0.0049 0.0224 0.0224
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0374 0.0411
Loa Loa (eye worm) beta-lactamase 0.0037 0.0146 0.0146
Schistosoma mansoni biogenic amine receptor 0.0078 0.042 0.0462
Onchocerca volvulus 0.0037 0.0146 0.0514
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0146 0.016
Schistosoma mansoni histamine h1 receptor 0.0078 0.042 0.0462
Leishmania major C-14 sterol reductase, putative 0.0049 0.0224 0.0224
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0268 0.1704 0.1704
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.093 0.6178 0.6788
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0128 0.014
Brugia malayi bZIP transcription factor family protein 0.0086 0.0479 0.0479
Loa Loa (eye worm) doublecortin family protein 0.002 0.0032 0.0032
Brugia malayi sulfakinin receptor protein 0.0078 0.042 0.042
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0006
Echinococcus granulosus jun protein 0.0086 0.0479 0.0526
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0268 0.1704 0.1868
Echinococcus granulosus fmrfamide receptor 0.0078 0.042 0.0462
Giardia lamblia 20S proteasome alpha subunit 3 0.0268 0.1704 0.1836
Brugia malayi Protein kinase domain containing protein 0.0016 0.0005 0.0005
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0105 0.0608 0.0668
Onchocerca volvulus 0.015 0.0911 0.3314
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0004 0.0004
Onchocerca volvulus 0.0078 0.042 0.152
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0078 0.042 0.0462
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0144 0.0158
Onchocerca volvulus Peroxidase homolog 0.0027 0.0078 0.0267
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.1362 0.9102 0.9102
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0181 0.0181
Echinococcus granulosus neuropeptides capa receptor 0.0078 0.042 0.0462
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0071 0.0374 0.0411
Loa Loa (eye worm) hypothetical protein 0.0042 0.0181 0.0181
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0043 0.0042
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0268 0.1704 0.1868
Schistosoma mansoni hypothetical protein 0.0313 0.2009 0.2208
Plasmodium vivax proteasome subunit beta type-5, putative 0.1362 0.9102 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.042 0.0462
Brugia malayi Protein kinase domain containing protein 0.0016 0.0005 0.0005
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0268 0.1704 0.1704
Onchocerca volvulus 0.0027 0.0078 0.0267
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Leishmania major proteasome beta 2 subunit, putative 0.0656 0.4327 0.4327
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.015 0.0165
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0181 0.0198
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0078 0.042 0.0462
Entamoeba histolytica hypothetical protein 0.002 0.0028 0.0026
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0032 0.0035
Trypanosoma cruzi Emopamil binding protein, putative 0.0421 0.2739 0.2739
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0268 0.1704 0.1704
Schistosoma mansoni retinoid-x-receptor (RXR) 0.015 0.0911 0.1001
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0268 0.1704 0.1872
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0268 0.1704 0.1872
Toxoplasma gondii ABC1 family protein 0.0037 0.0146 0.0154
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.009
Schistosoma mansoni neuropeptide receptor 0.0078 0.042 0.0462
Mycobacterium leprae proteasome (beta subunit) PrcB 0.1362 0.9102 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0028 0.0031
Brugia malayi CXXC zinc finger family protein 0.003 0.0095 0.0095
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0268 0.1704 0.1704
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0374 0.0411
Trypanosoma brucei Emopamil binding protein, putative 0.0421 0.2739 0.2739
Brugia malayi Doublecortin family protein 0.002 0.0032 0.0032
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0268 0.1704 0.1704
Echinococcus multilocularis peroxidasin 0.0027 0.0078 0.0086
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0181 0.0181
Leishmania major p-glycoprotein 0.0022 0.0042 0.0042
Schistosoma mansoni thyroid hormone receptor 0.015 0.0911 0.1001
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.1362 0.9102 1
Trypanosoma brucei proteasome beta 7 subunit 0.0268 0.1704 0.1704
Onchocerca volvulus 0.0078 0.042 0.152
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0146 0.0154
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.042 0.0462
Onchocerca volvulus Notchless protein homolog 0.0268 0.1704 0.6216
Echinococcus granulosus neuropeptide receptor 0.0078 0.042 0.0462
Schistosoma mansoni multidrug resistance protein 0.0022 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.0064 0.0326 0.0326
Brugia malayi G-protein coupled receptor 0.0078 0.042 0.042
Brugia malayi Nuclear hormone receptor-like 1 0.015 0.0911 0.0911
Schistosoma mansoni hypothetical protein 0.002 0.0032 0.0035
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.015 0.0911 0.1001
Echinococcus granulosus c src tyrosine kinase 0.0024 0.0056 0.0061
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Echinococcus multilocularis neuropeptide Y receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0146 0.0146
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0268 0.1704 0.1868
Onchocerca volvulus 0.0078 0.042 0.152
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Brugia malayi Cytochrome P450 family protein 0.0061 0.0308 0.0308
Entamoeba histolytica P-glycoprotein-5 0.0022 0.0042 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.042 0.0462
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0268 0.1704 1
Schistosoma mansoni Lamin B receptor (ERG24) 0.0049 0.0224 0.0246
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.0172 0.1055 0.1159
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0042 0.0046
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0268 0.1704 0.1704
Echinococcus multilocularis tyrosine kinase 0.0016 0.0005 0.0005
Loa Loa (eye worm) serotonin transporter b 0.0249 0.1576 0.1576
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0199 0.124 0.1363
Mycobacterium ulcerans hypothetical protein 0.0037 0.0146 0.0113
Brugia malayi nuclear hormone receptor 0.015 0.0911 0.0911
Brugia malayi proteasome subunit beta type 1 0.1058 0.7048 0.7048
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Toxoplasma gondii hypothetical protein 0.0042 0.0181 0.0193
Leishmania major importin beta-1 subunit, putative 0.0024 0.0056 0.0056
Schistosoma mansoni loxhd1 0.002 0.0032 0.0035
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0199 0.124 0.1363
Leishmania major proteasome alpha 1 subunit, putative 0.0268 0.1704 0.1704
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0656 0.4327 0.4754
Schistosoma mansoni amine GPCR 0.0418 0.2723 0.2992
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0043 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0004 0.0004
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Loa Loa (eye worm) PDE1B protein 0.0199 0.124 0.124
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0098 0.0108
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0042 0.0046
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0078 0.042 0.0462
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0421 0.2739 0.2739
Schistosoma mansoni biogenic amine receptor 0.0078 0.042 0.0462
Giardia lamblia Proteasome subunit beta type 2 0.0656 0.4327 0.4731
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0043 0.0042
Echinococcus granulosus tyrosine protein kinase Lyn 0.0054 0.0259 0.0284
Giardia lamblia 20S proteasome alpha subunit 1 0.0268 0.1704 0.1836
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0078 0.042 0.0462
Onchocerca volvulus 0.0078 0.042 0.152
Plasmodium falciparum importin beta, putative 0.0029 0.0093 0.0097
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0268 0.1704 0.1868
Echinococcus multilocularis neuropeptides capa receptor 0.0078 0.042 0.0462
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0078 0.042 0.042
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0032 0.0035
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0042 0.0046
Schistosoma mansoni gabp alpha 0.0074 0.0399 0.0438
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0268 0.1704 0.1868
Plasmodium vivax amine transporter, putative 0.0042 0.0181 0.0193
Mycobacterium tuberculosis Conserved protein 0.0037 0.0146 0.0154
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0238 0.0238
Echinococcus multilocularis proteasome subunit alpha type 6 0.0268 0.1704 0.1872
Echinococcus multilocularis g-protein coupled receptor 0.0078 0.042 0.0462
Schistosoma mansoni biogenic amine receptor 0.0078 0.042 0.0462
Trichomonas vaginalis ran, putative 0.0022 0.0041 0.0045
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0027 0.0075 0.0036
Loa Loa (eye worm) hypothetical protein 0.0079 0.0432 0.0432
Onchocerca volvulus Protein ultraspiracle homolog 0.015 0.0911 0.3314
Echinococcus granulosus alpha 1A adrenergic receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) hypothetical protein 0.0037 0.0146 0.0146
Brugia malayi nuclear hormone receptor family member odr-7 0.0071 0.0374 0.0374
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0027 0.0075 0.0075
Echinococcus granulosus tachykinin peptides receptor 99D 0.0078 0.042 0.0462
Brugia malayi follicle stimulating hormone receptor 0.0355 0.2298 0.2298
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0175 0.0193
Brugia malayi Ets-domain containing protein 0.0074 0.0399 0.0399
Brugia malayi Peroxidasin 0.0027 0.0078 0.0078
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0004 0.0004
Onchocerca volvulus 0.0042 0.0181 0.0643
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.042 0.0462
Schistosoma mansoni tyrosine kinase 0.0163 0.0998 0.1096
Echinococcus granulosus tm gpcr rhodopsin 0.093 0.6178 0.6788
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0027 0.0075 0.0075
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0004 0.0004
Leishmania major proteasome beta 2 subunit, putative 0.0268 0.1704 0.1704
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.015 0.0911 0.1001
Echinococcus granulosus allatostatin A receptor 0.0078 0.042 0.0462
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0042 0.0046
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0268 0.1704 0.1868
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0144 0.0158
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0146 0.016
Plasmodium vivax SET domain protein, putative 0.0031 0.0107 0.0112
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0268 0.1704 0.1704
Echinococcus granulosus Proteasome subunit alpha beta 0.0268 0.1704 0.1872
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0105 0.0608 0.0663
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0105 0.0608 0.0608
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0268 0.1704 0.1868
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.1137 0.1249
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0268 0.1704 0.1704
Echinococcus granulosus orexin receptor type 2 0.0078 0.042 0.0462
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0146 0.0154
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0056 0.0056
Schistosoma mansoni thyroid hormone receptor 0.015 0.0911 0.1001
Brugia malayi Proteasome A-type and B-type family protein 0.0268 0.1704 0.1704
Echinococcus multilocularis 0.0022 0.0043 0.0047
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0054 0.0259 0.0284
Loa Loa (eye worm) neuropeptide F receptor 0.0078 0.042 0.042
Schistosoma mansoni tyrosine kinase 0.0054 0.0259 0.0284
Loa Loa (eye worm) hypothetical protein 0.0079 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0093 0.0102
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0268 0.1704 0.1868
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0208 0.0228
Echinococcus granulosus Proteasome subunit alpha type 7 0.0268 0.1704 0.1872
Schistosoma mansoni transcription factor btf3 0.0036 0.0138 0.0152
Echinococcus multilocularis allatostatin A receptor 0.0078 0.042 0.0462
Onchocerca volvulus 0.0071 0.0374 0.1352
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0268 0.1704 0.1872
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0078 0.042 0.0462
Schistosoma mansoni hypothetical protein 0.0078 0.042 0.0462
Onchocerca volvulus 0.006 0.0299 0.1075
Echinococcus multilocularis jun protein 0.0086 0.0479 0.0526
Schistosoma mansoni regulator of G protein signaling 0.002 0.0028 0.0031
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0268 0.1704 0.1868
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.042 0.0462
Echinococcus granulosus g protein coupled receptor 0.0078 0.042 0.0462
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0043 0.0042
Schistosoma mansoni hypothetical protein 0.0022 0.0043 0.0047
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0042 0.0046
Onchocerca volvulus Bile acid receptor homolog 0.015 0.0911 0.3314
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0181 0.0198
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0259 0.0284
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0268 0.1704 0.1868
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0259 0.0284
Trichomonas vaginalis abcb9, putative 0.0022 0.0042 0.0046
Brugia malayi Tyrosine-protein kinase abl-1 0.0024 0.0056 0.0056
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.015 0.0911 0.1001
Giardia lamblia Proteasome subunit beta type 5 precursor 0.1362 0.9102 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.015 0.0911 0.1001
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0268 0.1704 0.1872
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0005 0.0006
Leishmania major cytochrome p450-like protein 0.0022 0.0043 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.1073 0.1179
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1495 1 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0028 0.0028
Echinococcus granulosus proteasome prosome macropain 0.1362 0.9102 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0042 0.0046
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1362 0.9102 0.9102
Entamoeba histolytica hypothetical protein 0.0036 0.0138 0.0147
Schistosoma mansoni rab6-interacting 0.002 0.0032 0.0035
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0268 0.1704 0.1704
Echinococcus granulosus proteasome subunit alpha type 6 0.0268 0.1704 0.1872
Plasmodium vivax proteasome subunit beta type-4, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Entamoeba histolytica hypothetical protein 0.002 0.0028 0.0026
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0078 0.042 0.0462
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.042 0.0462
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0268 0.1704 0.1872
Onchocerca volvulus Peroxidasin homolog 0.0027 0.0078 0.0267
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0078 0.042 0.0462
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0042 0.0046
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0374 0.0411
Brugia malayi Fli-1 protein 0.0226 0.1424 0.1424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.008 0.0088
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0268 0.1704 0.1704
Schistosoma mansoni myosin xvIII 0.0078 0.042 0.0462
Brugia malayi Nuclear hormone receptor family member nhr-41 0.015 0.0911 0.0911
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0041 0.0039
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0656 0.4327 0.4754
Trypanosoma cruzi polyprenyl synthase, putative 0.0027 0.0075 0.0075
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0107 0.0118
Brugia malayi G protein-coupled receptor 0.0078 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Schistosoma mansoni ran 0.0022 0.0041 0.0045
Loa Loa (eye worm) polyprenyl synthetase 0.0027 0.0075 0.0075
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0374 0.0411
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0399 0.0438
Brugia malayi Cytochrome P450 family protein 0.0031 0.0104 0.0104
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0656 0.4327 0.4754
Entamoeba histolytica protein kinase, putative 0.0038 0.0155 0.0165
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Leishmania major hypothetical protein, conserved 0.0037 0.0146 0.0146
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0152 0.0152
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0078 0.042 0.0462
Echinococcus granulosus proteasome subunit alpha type 2 0.0268 0.1704 0.1872
Loa Loa (eye worm) hypothetical protein 0.0079 0.0432 0.0432
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0268 0.1704 0.1872
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0042 0.0046
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0181 0.0198
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.1058 0.7048 0.7744
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0128 0.014
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0028
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0268 0.1704 0.1704
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0656 0.4327 0.4754
Echinococcus granulosus 7tm_1 domain containing protein 0.0078 0.042 0.0462
Entamoeba histolytica P-glycoprotein-1 0.0022 0.0042 0.0041
Schistosoma mansoni hypothetical protein 0.0078 0.042 0.0462
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0268 0.1704 0.1704
Brugia malayi nuclear receptor RXR 0.0079 0.0432 0.0432
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0064 0.007
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0268 0.1704 0.1704
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0268 0.1704 0.1868
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0152 0.0167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.042 0.0462
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0208 0.0208
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0268 0.1704 0.1704
Onchocerca volvulus 0.0078 0.042 0.152
Schistosoma mansoni growth hormone secretagogue receptor 0.0078 0.042 0.0462
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0042 0.0041
Schistosoma mansoni amine GPCR 0.0078 0.042 0.0462
Entamoeba histolytica Ran family GTPase 0.0022 0.0041 0.004
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0028 0.0031
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Brugia malayi Protein kinase domain containing protein 0.0105 0.0603 0.0603
Trypanosoma cruzi C-14 sterol reductase, putative 0.0049 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0146 0.0146
Brugia malayi ecdysteroid receptor 0.015 0.0911 0.0911
Onchocerca volvulus 0.0042 0.0181 0.0643
Onchocerca volvulus 0.0078 0.042 0.152
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0268 0.1704 0.1872
Plasmodium vivax proteasome subunit beta type-7, putative 0.0268 0.1704 0.1868
Echinococcus multilocularis neuropeptide receptor 0.0078 0.042 0.0462
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0043 0.0043
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0107 0.0118
Onchocerca volvulus 0.0078 0.042 0.152
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0268 0.1704 0.1868
Brugia malayi proteasome subunit alpha type 2 0.0268 0.1704 0.1704
Loa Loa (eye worm) neuropeptide F receptor 0.0078 0.042 0.042
Brugia malayi hypothetical protein 0.0125 0.0742 0.0742
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0268 0.1704 0.1872
Schistosoma mansoni tyrosine kinase 0.0105 0.0603 0.0663
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0268 0.1704 0.1872
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0042 0.0046
Schistosoma mansoni peroxidasin 0.0027 0.0078 0.0086
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0208 0.0223
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.1073 0.1179
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0024 0.0056 0.0061
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.015 0.0911 0.0911
Schistosoma mansoni nuclear receptor 0.0071 0.0374 0.0411
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0028 0.0031
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0268 0.1704 0.1704
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0181 0.0193
Echinococcus granulosus tyrosine kinase 0.0046 0.0208 0.0228
Trypanosoma cruzi 20S proteasome subunit 0.0656 0.4327 0.4327
Echinococcus granulosus hypothetical protein 0.0788 0.5218 0.5733
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0175 0.0193
Echinococcus granulosus proteasome subunit beta type 7 0.0268 0.1704 0.1872
Onchocerca volvulus 0.002 0.0032 0.01
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0054 0.0259 0.0284
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0078 0.0078
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0146 0.0154
Schistosoma mansoni hypothetical protein 0.0078 0.042 0.0462
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.015 0.0911 0.0911
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0268 0.1704 0.1704
Mycobacterium ulcerans lipase LipD 0.0037 0.0146 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0028 0.0031
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.0138 0.0138
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.1691 0.1858
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0086 0.0479 0.0526
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0208 0.0208
Onchocerca volvulus 0.0249 0.1576 0.5748
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0028 0.0031
Schistosoma mansoni cpg binding protein 0.0031 0.0106 0.0117
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0043 0.0042
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.042 0.0462
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.015 0.0911 0.1001
Brugia malayi RNA, U transporter 1 0.0083 0.0458 0.0458
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.1691 0.1858
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0181 0.0198
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0042 0.0046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.042 0.0462
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0135 0.0148
Onchocerca volvulus Neuropeptide F receptor homolog 0.0078 0.042 0.152
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0042 0.0181 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0043 0.0042
Loa Loa (eye worm) ICD-1 protein 0.0036 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0028
Onchocerca volvulus 0.0068 0.0354 0.1276
Loa Loa (eye worm) hypothetical protein 0.0033 0.0118 0.0118
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0268 0.1704 0.1868
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.042 0.0462
Echinococcus multilocularis epidermal growth factor receptor 0.0314 0.2015 0.2213
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0079 0.0432 0.0432
Loa Loa (eye worm) TK protein kinase 0.0038 0.0155 0.0155
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0078 0.0078
Brugia malayi Nuclear hormone receptor-like 1 0.0079 0.0432 0.0432
Echinococcus multilocularis transcription factor btf3 0.0036 0.0138 0.0152
Echinococcus multilocularis neuropeptide receptor A26 0.0078 0.042 0.0462
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0268 0.1704 0.1868
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0042 0.0046
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0042 0.0046
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.0042 0.0042
Echinococcus granulosus peroxidasin 0.0027 0.0078 0.0086
Brugia malayi cytochrome P450 0.0022 0.0043 0.0043
Leishmania major basic transcription factor 3a, putative 0.0036 0.0138 0.0138
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0024 0.0056 0.0061
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0268 0.1704 0.1868
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0268 0.1704 0.1704
Onchocerca volvulus 0.0078 0.042 0.152
Loa Loa (eye worm) hypothetical protein 0.0042 0.0181 0.0181
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1362 0.9102 1
Toxoplasma gondii proteasome subunit 0.0268 0.1704 0.1868
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0268 0.1704 0.1704
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0093 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.015 0.0911 0.0911
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0016 0.0005 0.0005
Plasmodium vivax multidrug resistance protein 1, putative 0.0022 0.0042 0.004
Echinococcus multilocularis proteasome subunit beta type 6 0.0268 0.1704 0.1872
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0208 0.0228
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) melatonin receptor type 1A 0.0078 0.042 0.042
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.042 0.0462
Loa Loa (eye worm) hypothetical protein 0.015 0.0911 0.0911
Giardia lamblia Proteasome subunit beta type 1 0.1058 0.7048 0.7733
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.1362 0.9102 1
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0268 0.1704 0.1872
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.042 0.0462
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0105 0.0608 0.0608
Trichomonas vaginalis taga, putative 0.0022 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.0042 0.0181 0.0181
Leishmania major solanesyl-diphosphate synthase, putative 0.0027 0.0075 0.0075
Onchocerca volvulus 0.0078 0.042 0.152
Trypanosoma cruzi sterol C-24 reductase, putative 0.0049 0.0224 0.0224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0105 0.0115
Echinococcus multilocularis lamin b receptor 0.0049 0.0224 0.0246
Echinococcus granulosus dro:myosuppressin receptor 0.0078 0.042 0.0462
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0028 0.0031
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0078 0.042 0.0462
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0268 0.1704 0.1868
Echinococcus granulosus lamin b receptor 0.0049 0.0224 0.0246
Loa Loa (eye worm) nuclear hormone receptor 0.0071 0.0374 0.0374
Trichomonas vaginalis abcb9, putative 0.0022 0.0042 0.0046
Echinococcus granulosus transcription factor btf3 0.0036 0.0138 0.0152
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0071 0.0374 0.0411
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0208 0.0208
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0028 0.0031
Echinococcus granulosus cpg binding protein 0.0031 0.0106 0.0117
Brugia malayi neuropeptide F receptor 0.0078 0.042 0.042
Onchocerca volvulus 0.0078 0.042 0.152
Loa Loa (eye worm) hypothetical protein 0.0035 0.0129 0.0129
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0764 0.506 0.506
Echinococcus granulosus axis inhibition protein axin 0.002 0.0028 0.0031
Loa Loa (eye worm) solute carrier family 6 member 4 0.0249 0.1576 0.1576
Brugia malayi tailless protein 0.0071 0.0374 0.0374
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0268 0.1704 0.1868
Plasmodium vivax proteasome subunit beta type-2, putative 0.0656 0.4327 0.4751
Leishmania major proteasome alpha 3 subunit, putative 0.0268 0.1704 0.1704
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0043 0.0042
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0268 0.1704 0.1704
Trypanosoma brucei proteasome alpha 7 subunit 0.0268 0.1704 0.1704
Echinococcus multilocularis FTZ F1 alpha 0.015 0.0911 0.1001
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0078 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.015 0.0911 0.0911
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0715 0.0786
Schistosoma mansoni nuclear receptor 0.0071 0.0374 0.0411
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.015 0.0911 0.1001
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0105 0.0603 0.0663
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0016 0.0005 0.0005
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0181 0.0198
Brugia malayi hypothetical protein 0.0016 0.0005 0.0005
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0268 0.1704 0.1868
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0043 0.0042
Brugia malayi conserved hypotetical protein 0.0071 0.0374 0.0374
Brugia malayi Ets-domain containing protein 0.0074 0.0399 0.0399
Echinococcus multilocularis geminin 0.0174 0.1073 0.1179
Onchocerca volvulus 0.0071 0.0374 0.1352
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.1362 0.9102 1
Trypanosoma brucei cytochrome P450, putative 0.0031 0.0104 0.0104
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0042 0.0046
Schistosoma mansoni hypothetical protein 0.007 0.037 0.0406
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0656 0.4327 0.4751
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Echinococcus granulosus neuropeptide Y receptor 0.0078 0.042 0.0462
Echinococcus multilocularis orexin receptor type 2 0.0078 0.042 0.0462
Echinococcus multilocularis sex peptide receptor 0.0078 0.042 0.0462
Echinococcus granulosus neuropeptide receptor 0.0078 0.042 0.0462
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0181 0.0198
Plasmodium vivax proteasome subunit beta type-3, putative 0.0268 0.1704 0.1868
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0268 0.1704 0.1704
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0268 0.1704 0.1868
Brugia malayi putative neuropeptide receptor NPR1 0.0078 0.042 0.042
Schistosoma mansoni ets-related 0.0226 0.1424 0.1564
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0027 0.0075 0.0077
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0146 0.0154
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Plasmodium vivax importin-beta 2, putative 0.0029 0.0093 0.0097
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0005 0.0006
Echinococcus multilocularis ecdysone induced protein 78C 0.015 0.0911 0.1001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0107 0.0112
Echinococcus multilocularis tyrosine protein kinase shark 0.0016 0.0005 0.0005
Echinococcus multilocularis g protein coupled receptor 0.0078 0.042 0.0462
Brugia malayi beta-lactamase 0.0037 0.0146 0.0146
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0259 0.0284
Echinococcus multilocularis g protein coupled receptor 0.0078 0.042 0.0462
Echinococcus granulosus serotonin receptor 0.0078 0.042 0.0462
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0268 0.1704 0.1868
Echinococcus granulosus biogenic amine 5HT receptor 0.0203 0.1267 0.1392
Brugia malayi hypothetical protein 0.0071 0.0374 0.0374
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0105 0.0608 0.0624
Schistosoma mansoni neuropeptide receptor 0.0078 0.042 0.0462
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0042 0.0046
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0104 0.0104
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0042 0.0041
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0042 0.0046
Leishmania major C-8 sterol isomerase-like protein 0.1495 1 1
Echinococcus multilocularis RUN 0.002 0.0032 0.0035
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0042 0.0046
Brugia malayi hypothetical protein 0.0042 0.0181 0.0181
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0308 0.0308
Schistosoma mansoni regulator of G protein signaling 0.002 0.0028 0.0031
Echinococcus granulosus GPCR family 2 0.0016 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0028 0.0031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0146 0.0146
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0268 0.1704 0.1704
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.1691 0.1858
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0078 0.042 0.0462
Leishmania major proteasome alpha 7 subunit, putative 0.0268 0.1704 0.1704
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0146 0.016
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0042 0.0046
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0268 0.1704 0.1872
Leishmania major proteasome beta 3 subunit, putative 0.0268 0.1704 0.1704
Brugia malayi GnHR receptor homolog 0.0078 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0181 0.0181
Mycobacterium tuberculosis Conserved protein 0.0037 0.0146 0.0154
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) hypothetical protein 0.015 0.0911 0.0911
Echinococcus granulosus RUN 0.002 0.0032 0.0035
Echinococcus granulosus FTZ F1 alpha 0.015 0.0911 0.1001
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.0042 0.0041
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.1058 0.7048 0.7048
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0042 0.0046
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0268 0.1704 0.1704
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0374 0.0411
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0268 0.1704 0.1872
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.1691 0.1858
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0027 0.0075 0.0083
Trypanosoma cruzi Emopamil binding protein, putative 0.0421 0.2739 0.2739
Onchocerca volvulus 0.0031 0.0107 0.0374
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0078 0.042 0.0462
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0181 0.0198
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0093 0.0097
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Schistosoma mansoni tyrosine kinase 0.0314 0.2015 0.2213
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0105 0.0603 0.0663
Echinococcus multilocularis thyroid hormone receptor alpha 0.015 0.0911 0.1001
Loa Loa (eye worm) norepinephrine transporter 0.0249 0.1576 0.1576
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0028
Toxoplasma gondii hypothetical protein 0.0042 0.0181 0.0193
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.0104 0.0067
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Echinococcus granulosus nuclear receptor nhr 48 0.0071 0.0374 0.0411
Echinococcus multilocularis fmrfamide receptor 0.0078 0.042 0.0462
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.015 0.0911 0.1001
Echinococcus granulosus tyrosine protein kinase Src42A 0.0054 0.0259 0.0284
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0041 0.0039
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0028 0.0031
Schistosoma mansoni lipoxygenase 0.0121 0.0715 0.0786
Echinococcus multilocularis dro:myosuppressin receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Brugia malayi steroid hormone receptor 0.015 0.0911 0.0911
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.1073 0.1179
Schistosoma mansoni smdr2 0.0022 0.0042 0.0046
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0022 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0268 0.1704 0.1872
Echinococcus multilocularis expressed protein 0.0384 0.249 0.2736
Loa Loa (eye worm) hypothetical protein 0.0084 0.0463 0.0463
Entamoeba histolytica hypothetical protein 0.002 0.0028 0.0026
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0268 0.1704 0.1868
Echinococcus granulosus tumor protein p63 0.0408 0.2653 0.2915
Brugia malayi putative neuropeptide receptor 0.0078 0.042 0.042
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.1058 0.7048 0.7048
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0268 0.1704 0.1868
Echinococcus multilocularis g protein coupled receptor 0.0078 0.042 0.0462
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Schistosoma mansoni cpg binding protein 0.003 0.0095 0.0104
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.015 0.0911 0.0911
Loa Loa (eye worm) TK/ABL protein kinase 0.0016 0.0005 0.0005
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0042 0.0181 0.0181
Echinococcus granulosus tyrosine protein kinase shark 0.0016 0.0005 0.0005
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0004 0.0004
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0043 0.0043
Onchocerca volvulus 0.0078 0.042 0.152
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0181 0.0181
Brugia malayi Proteasome subunit alpha type 1 0.0268 0.1704 0.1704
Schistosoma mansoni sodium-dependent amino acid transporter 0.0042 0.0181 0.0198
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0259 0.0284
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0268 0.1704 0.1868
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0071 0.0374 0.0411
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.015 0.0911 0.1001
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.0138 0.0146
Echinococcus multilocularis neuropeptide s receptor 0.0078 0.042 0.0462
Entamoeba histolytica proteasome subunit beta type 1, putative 0.1058 0.7048 0.7742
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0107 0.0118
Onchocerca volvulus 0.002 0.0032 0.01
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0028 0.0031
Loa Loa (eye worm) hypothetical protein 0.0504 0.3299 0.3299
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0006
Loa Loa (eye worm) PAS-3 protein 0.0268 0.1704 0.1704
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0268 0.1704 0.1704
Schistosoma mansoni regulator of G protein signaling 0.002 0.0028 0.0031
Brugia malayi beta-lactamase family protein 0.0037 0.0146 0.0146
Schistosoma mansoni tyrosine kinase 0.0163 0.0998 0.1096
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0656 0.4327 0.4751
Brugia malayi beta-NAC-like protein 0.0036 0.0138 0.0138
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0027 0.0075 0.0083
Loa Loa (eye worm) hypothetical protein 0.0037 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.004
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0028 0.0031
Onchocerca volvulus Chorion peroxidase homolog 0.0027 0.0078 0.0267
Brugia malayi Protein kinase domain containing protein 0.0016 0.0005 0.0005
Loa Loa (eye worm) CYP4Cod1 0.0031 0.0104 0.0104
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0208 0.0208
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0078 0.042 0.0462
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0027 0.0075 0.0077
Loa Loa (eye worm) hypothetical protein 0.0037 0.0146 0.0146
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0268 0.1704 0.1836
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) hypothetical protein 0.0079 0.0432 0.0432
Schistosoma mansoni biogenic amine (5HT) receptor 0.0203 0.1267 0.1392
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0027 0.0075 0.24
Brugia malayi Nuclear hormone receptor-like 1 0.0079 0.0432 0.0432
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0268 0.1704 0.1872
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0064 0.007
Loa Loa (eye worm) SRC-1 0.0054 0.0259 0.0259
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0078 0.042 0.042
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0268 0.1704 0.1872
Trichomonas vaginalis abcb9, putative 0.0022 0.0042 0.0046
Loa Loa (eye worm) fli-1 protein 0.0226 0.1424 0.1424
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.042 0.0462
Schistosoma mansoni hypothetical protein 0.0421 0.2739 0.3009
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0078 0.0078
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0078 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0268 0.1704 0.1704
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.1691 0.1858
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0268 0.1704 0.1704
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0146 0.0154
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0028 0.0031
Schistosoma mansoni tyrosine kinase 0.0016 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0064 0.007
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0268 0.1704 0.1868
Brugia malayi Protein kinase domain containing protein 0.0016 0.0005 0.0005
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0268 0.1704 0.1704
Schistosoma mansoni nuclear receptor nhr-48 0.0071 0.0374 0.0411
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0374 0.0411
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0105 0.0608 0.0663
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0399 0.0399
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0146 0.0146
Schistosoma mansoni RAR-like nuclear receptor 0.015 0.0911 0.1001
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0181 0.0198
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0027 0.0075 0.0077
Echinococcus granulosus proteasome prosome macropain subunit beta 0.1058 0.7048 0.7744
Schistosoma mansoni opsin-like receptor 0.0078 0.042 0.0462
Echinococcus granulosus tyrosine protein kinase Srms 0.0016 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0144 0.0158
Schistosoma mansoni axis inhibition protein axin 0.002 0.0028 0.0031
Echinococcus granulosus neuropeptide s receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0005 0.0005
Giardia lamblia GTOR 0.0046 0.0208 0.0184
Schistosoma mansoni opsin-like receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.015 0.0911 0.0911
Echinococcus granulosus microtubule associated protein 2 0.071 0.4693 0.5156
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0104 0.0104
Trypanosoma cruzi sterol C-24 reductase, putative 0.0049 0.0224 0.0224
Brugia malayi hypothetical protein 0.0079 0.0432 0.0432
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0326 0.0359
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0024 0.0056 0.0061
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.015 0.0911 0.1001
Echinococcus granulosus tyrosine protein kinase Blk 0.0046 0.0208 0.0228
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Plasmodium falciparum proteasome subunit beta type-5 0.1362 0.9102 1
Echinococcus multilocularis fmrfamide receptor 0.0078 0.042 0.0462
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0268 0.1704 0.1872
Loa Loa (eye worm) hypothetical protein 0.0037 0.0146 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-19 0.015 0.0911 0.0911
Loa Loa (eye worm) RGS-3 protein 0.002 0.0028 0.0028
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.004 0.0044
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0208 0.0228
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0249 0.1576 0.1576
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0056 0.0061
Brugia malayi Pre-SET motif family protein 0.0215 0.1347 0.1347
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0078 0.042 0.042
Entamoeba histolytica hypothetical protein 0.0024 0.0056 0.0056
Echinococcus granulosus geminin 0.0174 0.1073 0.1179
Giardia lamblia 20S proteasome alpha subunit 5 0.0268 0.1704 0.1836
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0054 0.0259 0.0284
Giardia lamblia 20S proteasome alpha subunit 7 0.0268 0.1704 0.1836
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0268 0.1704 0.1872
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0268 0.1704 0.1872
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0027 0.0075 0.0083
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0028 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-25 0.015 0.0911 0.0911
Leishmania major GTP-binding protein, putative 0.0022 0.0041 0.0041
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.042 0.0462
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0181 0.0198
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0028 0.0028
Echinococcus granulosus neuropeptides capa receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Schistosoma mansoni peroxidasin 0.0027 0.0078 0.0086
Brugia malayi SRC-1 0.0054 0.0259 0.0259
Brugia malayi beta-lactamase family protein 0.0037 0.0146 0.0146
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0005 0.0005
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.1058 0.7048 0.7744
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0054 0.0259 0.0284
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.015 0.0165
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0071 0.0374 0.0411
Toxoplasma gondii proteasome subunit beta type, putative 0.1362 0.9102 1
Echinococcus multilocularis snurportin 1 0.0313 0.2009 0.2208
Onchocerca volvulus 0.0078 0.042 0.152
Echinococcus multilocularis neuropeptide Y receptor 0.0078 0.042 0.0462
Trypanosoma cruzi C-14 sterol reductase, putative 0.0049 0.0224 0.0224
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1362 0.9102 0.9102
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0268 0.1704 0.1872
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0043 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0043 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.042 0.0462
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0028 0.0031
Schistosoma mansoni neuropeptide f receptor 76f 0.0078 0.042 0.0462
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0268 0.1704 0.1704
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0268 0.1704 0.1704
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Echinococcus multilocularis tyrosine protein kinase Abl 0.0024 0.0056 0.0061
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0078 0.042 0.0462
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0268 0.1704 0.1868
Brugia malayi Cytochrome P450 family protein 0.0022 0.0043 0.0043
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0041 0.0045
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0043 0.0042
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0268 0.1704 0.1704
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0144 0.0144
Toxoplasma gondii proteasome subunit alpha1, putative 0.0268 0.1704 0.1868
Echinococcus multilocularis proteasome subunit beta type 7 0.0268 0.1704 0.1872
Echinococcus multilocularis serotonin receptor 0.0203 0.1267 0.1392
Schistosoma mansoni zinc finger protein 0.0071 0.0374 0.0411
Giardia lamblia 20S proteasome alpha subunit 2 0.0268 0.1704 0.1836
Brugia malayi Nuclear hormone receptor family member nhr-25 0.015 0.0911 0.0911
Echinococcus granulosus biogenic amine 5HT receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Brugia malayi nuclear hormone receptor family member nhr-6 0.0071 0.0374 0.0374
Leishmania major proteasome alpha 2 subunit, putative 0.0268 0.1704 0.1704
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0144 0.0144
Brugia malayi proteasome subunit alpha type 6 0.0268 0.1704 0.1704
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.042 0.0462
Echinococcus granulosus thyroid hormone receptor alpha 0.0071 0.0374 0.0411
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.015 0.0911 0.1001
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0027 0.0075 0.0083
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0042 0.0046
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0259 0.0284
Brugia malayi hypothetical protein 0.002 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0004 0.0004
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0268 0.1704 0.1872
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0374 0.1352
Plasmodium vivax proteasome subunit beta type-1, putative 0.1058 0.7048 0.7742
Brugia malayi multidrug resistance protein 3 0.0022 0.0042 0.0042
Schistosoma mansoni adenoreceptor 0.0078 0.042 0.0462
Echinococcus granulosus expressed protein 0.0384 0.249 0.2736
Echinococcus granulosus nuclear receptor 2DBD gamma 0.015 0.0911 0.1001
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0281 0.0303
Mycobacterium ulcerans proteasome PrcB 0.1362 0.9102 1
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0268 0.1704 0.1704
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0027 0.0075 0.0077
Brugia malayi Dopamine receptor protein 1 0.0078 0.042 0.042
Schistosoma mansoni retinoic acid receptor RXR 0.015 0.0911 0.1001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0079 0.0432 0.0475
Brugia malayi AKH receptor 0.0078 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0259 0.0284
Brugia malayi Proteasome subunit alpha type 7-1 0.0268 0.1704 0.1704
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0068 0.0354 0.0389
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0042 0.0046
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0268 0.1704 0.1704
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0043 0.0042
Brugia malayi Polyprenyl synthetase family protein 0.0027 0.0075 0.0075
Brugia malayi nuclear receptor NHR-88 0.0071 0.0374 0.0374
Brugia malayi hypothetical protein 0.0079 0.0432 0.0432
Brugia malayi 20S proteasome alpha5 subunit 0.0268 0.1704 0.1704
Echinococcus granulosus epidermal growth factor receptor 0.0314 0.2015 0.2213
Echinococcus granulosus importin subunit beta 1 0.0029 0.0093 0.0102
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0041 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0107 0.0118
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.0042 0.0041
Brugia malayi Proteasome A-type and B-type family protein 0.1362 0.9102 0.9102
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0093 0.0093
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0005 0.0006
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0032 0.0035
Loa Loa (eye worm) hypothetical protein 0.015 0.0911 0.0911
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0146 0.016
Echinococcus granulosus tm gpcr rhodopsin 0.0078 0.042 0.0462
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0107 0.0118
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.015 0.0911 0.1001
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0027 0.0075 0.0077
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.015 0.0911 0.0911
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0041 0.0041
Leishmania major polyprenyl synthase, putative 0.0027 0.0075 0.0075
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0268 0.1704 0.1872
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.042 0.0462
Onchocerca volvulus 0.0244 0.1546 0.5639
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0041 0.0045
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0374 0.0374
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0105 0.0608 0.0668
Onchocerca volvulus 0.003 0.0095 0.0329
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0268 0.1704 0.1868
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0078 0.042 0.0462
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0268 0.1704 0.1872
Loa Loa (eye worm) hypothetical protein 0.0326 0.2101 0.2101
Trichomonas vaginalis esterase, putative 0.0037 0.0146 0.016
Echinococcus multilocularis tyrosine protein kinase Blk 0.0046 0.0208 0.0228
Echinococcus multilocularis tumor protein p63 0.0408 0.2653 0.2915
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0078 0.042 0.042
Loa Loa (eye worm) polyprenyl synthetase 0.0105 0.0608 0.0608
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0146 0.0154
Schistosoma mansoni amine GPCR 0.0078 0.042 0.0462
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Leishmania major hypothetical protein, conserved 0.0421 0.2739 0.2739
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0042 0.0046
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0037 0.0146 0.0146
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0032 0.003
Echinococcus granulosus G protein coupled receptor 139 0.0078 0.042 0.0462
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0299 0.0328
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0068 0.0354 0.0384
Brugia malayi Proteasome A-type and B-type family protein 0.0268 0.1704 0.1704
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0146 0.0146
Schistosoma mansoni lipoxygenase 0.0085 0.0468 0.0515
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0268 0.1704 0.1704
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0144 0.0158
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0146 0.0146
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0028 0.0031
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0268 0.1704 0.1834
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0086 0.0479 0.0526
Loa Loa (eye worm) G-protein coupled receptor 0.0078 0.042 0.042
Schistosoma mansoni hypothetical protein 0.0174 0.1073 0.1179
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0146 0.016
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.1073 0.1179
Schistosoma mansoni hypothetical protein 0.0174 0.1073 0.1179
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0054 0.0259 0.0284
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0656 0.4327 0.4327
Echinococcus granulosus nuclear receptor 2DBD gamma 0.015 0.0911 0.1001
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0172 0.1055 0.1159
Loa Loa (eye worm) hypothetical protein 0.0042 0.0181 0.0181
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0138 0.0138
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0268 0.1704 0.1704
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0054 0.0259 0.0284
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0042 0.0046
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0128 0.0135
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.042 0.0462
Echinococcus granulosus tyrosine protein kinase Src64B 0.0054 0.0259 0.0284
Echinococcus multilocularis proteasome (prosome, macropain) 0.1362 0.9102 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0028
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0042 0.0181 0.0198
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0656 0.4327 0.4754
Plasmodium falciparum transporter, putative 0.0042 0.0181 0.0193
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0016 0.0005 0.0005
Trypanosoma brucei proteasome beta 6 subunit 0.1058 0.7048 0.7048
Onchocerca volvulus Peroxidase homolog 0.0027 0.0078 0.0267
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0181 0.0198
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0268 0.1704 0.1704
Echinococcus multilocularis serotonin receptor 0.0203 0.1267 0.1392
Echinococcus granulosus tyrosine kinase 0.0016 0.0005 0.0005
Toxoplasma gondii proteasome subunit alpha type, putative 0.0268 0.1704 0.1868
Plasmodium falciparum proteasome subunit beta type-4 0.0268 0.1704 0.1868
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0268 0.1704 0.1704
Echinococcus granulosus snurportin 1 0.0313 0.2009 0.2208
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Brugia malayi proteasome subunit alpha type 1 0.0268 0.1704 0.1704
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0078 0.042 0.0462
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0268 0.1704 0.1868
Echinococcus multilocularis neuropeptide FF receptor 2 0.0078 0.042 0.0462
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0079 0.0432 0.0432
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0268 0.1704 0.1704
Schistosoma mansoni neuropeptide F-like receptor 0.0078 0.042 0.0462
Brugia malayi ABC transporter family protein 0.0022 0.0042 0.0042
Plasmodium falciparum amino acid transporter, putative 0.0042 0.0181 0.0193
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0181 0.0198
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0028 0.0031
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0656 0.4327 0.4327
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0078 0.042 0.0462
Echinococcus granulosus 7TM GPCR rhodopsin 0.0078 0.042 0.0462
Brugia malayi proteasome subunit beta type 2 0.0656 0.4327 0.4327
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Schistosoma mansoni importin beta-1 0.0029 0.0093 0.0102
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0249 0.1576 0.1732
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0028 0.0028
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0208 0.0208
Trichomonas vaginalis glucosylceramidase, putative 0.0184 0.1137 0.1249
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0004
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0105 0.0608 0.0663
Mycobacterium ulcerans proteasome PrcA 0.0268 0.1704 0.1834
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi hypothetical protein 0.0071 0.0374 0.0374
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0268 0.1704 0.1872
Schistosoma mansoni steroid hormone receptor ad4bp 0.015 0.0911 0.1001
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0028 0.0031
Trypanosoma cruzi polyprenyl synthase, putative 0.0027 0.0075 0.0075
Schistosoma mansoni microtubule-associated protein tau 0.071 0.4693 0.5156
Plasmodium falciparum proteasome subunit beta type-1, putative 0.1058 0.7048 0.7742
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0028 0.0031
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.009
Loa Loa (eye worm) hypothetical protein 0.0022 0.0042 0.0042
Trichomonas vaginalis set domain proteins, putative 0.0244 0.1546 0.1699
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0374 0.0411
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Toxoplasma gondii proteasome subunit beta type 1, putative 0.1058 0.7048 0.7742
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0028 0.0031
Brugia malayi hypothetical protein 0.002 0.0032 0.0032
Echinococcus granulosus retinoic acid receptor rxr beta a 0.015 0.0911 0.1001
Brugia malayi RE15519p 0.0078 0.042 0.042
Echinococcus multilocularis neuropeptides capa receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0238 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0128 0.014
Echinococcus granulosus tm gpcr rhodopsin 0.061 0.4019 0.4415
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0355 0.2298 0.2298
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.042 0.0462
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0005 0.0005
Loa Loa (eye worm) TK/INSR protein kinase 0.0105 0.0603 0.0603
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0268 0.1704 0.1872
Echinococcus granulosus tyrosine protein kinase HCK 0.0038 0.0155 0.0171
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0208 0.0228
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0078 0.042 0.0462
Brugia malayi Melatonin receptor type 1A 0.0078 0.042 0.042
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) proteasome subunit beta type 1 0.1058 0.7048 0.7048
Brugia malayi Pre-SET motif family protein 0.0031 0.0107 0.0107
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0032 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.1073 0.1179
Echinococcus multilocularis microtubule associated protein 2 0.071 0.4693 0.5156
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0042 0.0046
Schistosoma mansoni nuclear hormone receptor 0.015 0.0911 0.1001
Mycobacterium tuberculosis Conserved protein 0.0037 0.0146 0.0154
Leishmania major sterol C-24 reductase, putative 0.0049 0.0224 0.0224
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0006
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0043 0.0043
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0042 0.0181 0.0198
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0152 0.0152
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0208 0.0223
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0138 0.0138
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.042 0.0462
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0079 0.0432 0.0475
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0054 0.0259 0.0284
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0005 0.0005
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0027 0.0075 0.0077
Schistosoma mansoni trans-prenyltransferase 0.0027 0.0075 0.0083
Echinococcus granulosus neuropeptide Y receptor 0.0078 0.042 0.0462
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0181 0.0198
Toxoplasma gondii heat shock protein hslv, putative 0.0268 0.1704 0.1868
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0027 0.0075 0.0075
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0146 0.0113
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0071 0.0374 0.0411
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0068 0.0354 0.0354
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0028 0.0028
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0181 0.0193
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0042 0.0046
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0199 0.124 0.1363
Brugia malayi nuclear receptor RXR 0.0071 0.0374 0.0374
Brugia malayi proteasome subunit alpha type 4 0.0268 0.1704 0.1704
Leishmania major proteasome beta 5 subunit, putative 0.1362 0.9102 0.9102
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0208 0.0228
Loa Loa (eye worm) hypothetical protein 0.0203 0.1267 0.1267
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0105 0.0608 0.0624
Leishmania major cytochrome p450-like protein 0.0022 0.0043 0.0043
Schistosoma mansoni axis inhibition protein axin 0.002 0.0028 0.0031
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0374 0.0411
Entamoeba histolytica transcription factor BTF3, putative 0.0036 0.0138 0.0147
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0078 0.042 0.0462
Brugia malayi Nuclear hormone receptor family member nhr-1 0.015 0.0911 0.0911
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0068 0.0354 0.0389
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0146 0.016
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0078 0.0078
Schistosoma mansoni tyrosine kinase 0.0024 0.0056 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.042 0.0462
Echinococcus granulosus dnaJ subfamily B 0.0421 0.2739 0.3009
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0028
Brugia malayi Proteasome A-type and B-type family protein 0.0268 0.1704 0.1704
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0032 0.0035
Echinococcus granulosus somatostatin receptor 0.0078 0.042 0.0462
Echinococcus granulosus ecdysone induced protein 78C 0.015 0.0911 0.1001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0313 0.2009 0.2009
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0078 0.0078
Schistosoma mansoni alpha-1 adrenergic receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.015 0.0911 0.0911
Loa Loa (eye worm) proteasome subunit beta type 2 0.0656 0.4327 0.4327
Echinococcus multilocularis neuropeptide receptor 0.0078 0.042 0.0462
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0042 0.0046
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0268 0.1704 0.1704
Schistosoma mansoni tyrosine kinase 0.0163 0.0998 0.1096
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0095 0.0095
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0144 0.0144
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0268 0.1704 0.1872
Leishmania major proteasome alpha 7 subunit, putative 0.0268 0.1704 0.1704
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0071 0.0374 0.0374
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0268 0.1704 0.1872
Brugia malayi Protein kinase domain containing protein 0.0016 0.0005 0.0005
Brugia malayi hypothetical protein 0.002 0.0032 0.0032
Leishmania major farnesyl pyrophosphate synthase 0.0105 0.0608 0.0608
Schistosoma mansoni cytochrome P450 0.0022 0.0043 0.0047
Brugia malayi proteasome subunit alpha type 3 0.0268 0.1704 0.1704
Onchocerca volvulus 0.0022 0.0042 0.0135
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0068 0.0354 0.0354
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0079 0.0432 0.0475
Leishmania major proteasome beta 7 subunit, putative 0.0268 0.1704 0.1704
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0268 0.1704 0.1872
Echinococcus granulosus insulin receptor 0.0105 0.0603 0.0663
Brugia malayi ORL1-like opioid receptor 0.0078 0.042 0.042
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0028 0.0031
Brugia malayi Polyprenyl synthetase family protein 0.0105 0.0608 0.0608
Brugia malayi nuclear receptor NHR-88 0.015 0.0911 0.0911
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Echinococcus granulosus g-protein coupled receptor 0.0078 0.042 0.0462
Brugia malayi nuclear receptor NHR-67 0.0071 0.0374 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0138 0.0152
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.1058 0.7048 0.7048
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0042 0.0046
Brugia malayi orphan nuclear receptor NR2E1 0.0071 0.0374 0.0374
Brugia malayi photoreceptor-specific nuclear receptor 0.015 0.0911 0.0911
Schistosoma mansoni polycystin 1-related 0.002 0.0032 0.0035
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0068 0.0354 0.0384
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0374 0.0374
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Loa Loa (eye worm) TK protein kinase 0.0046 0.0208 0.0208
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0042 0.0181 0.0198
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0268 0.1704 0.1868
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.008 0.0088
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0042 0.004
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0042 0.0046
Echinococcus multilocularis c src tyrosine kinase 0.0024 0.0056 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0028 0.0031
Brugia malayi SH2 domain containing protein 0.0016 0.0005 0.0005
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0656 0.4327 0.4754
Onchocerca volvulus 0.0078 0.042 0.152
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0027 0.0075 0.0075
Echinococcus granulosus proteasome subunit beta t family 0.0268 0.1704 0.1872
Echinococcus granulosus serotonin transporter 0.0249 0.1576 0.1732
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0144 0.0158
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0042 0.0046
Brugia malayi Blistered cuticle protein 3 0.0027 0.0078 0.0078
Brugia malayi G-protein coupled receptor 0.0078 0.042 0.042
Schistosoma mansoni jun-related protein 0.007 0.037 0.0406
Loa Loa (eye worm) hypothetical protein 0.0042 0.0181 0.0181
Echinococcus multilocularis tyrosine protein kinase Srms 0.0046 0.0208 0.0228
Echinococcus granulosus tyrosine protein kinase ABL1 0.0016 0.0005 0.0005
Onchocerca volvulus 0.0027 0.0078 0.0267
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0266 0.1691 0.1691
Loa Loa (eye worm) nuclear receptor NHR-67 0.0071 0.0374 0.0374
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0268 0.1704 0.1868
Schistosoma mansoni multidrug resistance protein 0.0022 0.0042 0.0046
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0105 0.0608 0.0668
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.1073 0.1179
Echinococcus multilocularis 0.0095 0.0537 0.059
Onchocerca volvulus 0.0078 0.042 0.152
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0268 0.1704 0.1704
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Schistosoma mansoni ran 0.0022 0.0041 0.0045
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0071 0.0374 0.0374
Onchocerca volvulus Peroxidasin homolog 0.0027 0.0078 0.0267
Brugia malayi Serotonin receptor 0.0078 0.042 0.042
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0208 0.0228
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0268 0.1704 0.1704
Schistosoma mansoni tyrosine kinase 0.0172 0.1055 0.1159
Schistosoma mansoni tyrosine kinase 0.0016 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0043 0.0042
Echinococcus granulosus proteasome subunit beta type 6 0.0268 0.1704 0.1872
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0068 0.0354 0.0354
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0028 0.0028
Leishmania major cytochrome p450-like protein 0.0031 0.0104 0.0104
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0028 0.0031
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0268 0.1704 0.1704
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0078 0.042 0.152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0128 0.014
Brugia malayi Nuclear hormone receptor family member nhr-31 0.015 0.0911 0.0911
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0162 0.0178
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0268 0.1704 0.1872
Onchocerca volvulus Dual oxidase homolog 0.0027 0.0078 0.0267
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0042 0.0181 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0027 0.0075 0.0077
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.1495 0.1637
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0043 0.0042
Onchocerca volvulus 0.0421 0.2739 1
Echinococcus multilocularis insulin receptor 0.0105 0.0603 0.0663
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0078 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0043 0.0042
Giardia lamblia 20S proteasome alpha subunit 6 0.0268 0.1704 0.1836
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0268 0.1704 0.1704
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.042 0.0462
Brugia malayi Serotonin receptor 0.0551 0.3619 0.3619
Onchocerca volvulus Glucosylceramidase homolog 0.0174 0.1073 0.3908
Echinococcus multilocularis GPCR, family 2 0.0016 0.0004 0.0004
Loa Loa (eye worm) cytochrome P450 0.0022 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0078 0.042 0.0462
Brugia malayi Dopamine receptor protein 2 0.0078 0.042 0.042
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0268 0.1704 0.1872
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0042 0.0181 0.0198
Brugia malayi ecdysone receptor 0.0071 0.0374 0.0374
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0028 0.0031
Schistosoma mansoni regulator of G protein signaling 0.002 0.0028 0.0031
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0078 0.042 0.0462
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0138 0.0152
Onchocerca volvulus 0.0042 0.0181 0.0643
Loa Loa (eye worm) hypothetical protein 0.015 0.0911 0.0911
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0146 0.016
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0027 0.0075 0.0036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0181 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0128 0.014
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0027 0.0075 0.0075
Schistosoma mansoni multidrug resistance protein 0.0022 0.0042 0.0046
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.004 0.0044
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0268 0.1704 0.1704
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0128 0.014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.061 0.4019 0.4415
Loa Loa (eye worm) hypothetical protein 0.015 0.0911 0.0911
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0208 0.0208
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0208 0.0208
Schistosoma mansoni tyrosine kinase 0.0024 0.0056 0.0061
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0715 0.0786
Echinococcus multilocularis proteasome subunit alpha type 2 0.0268 0.1704 0.1872
Brugia malayi larval opioid receptor 0.0078 0.042 0.042
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.015 0.0911 0.1001
Loa Loa (eye worm) hypothetical protein 0.0504 0.3299 0.3299
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0043 0.0042
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0042 0.0046
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0028 0.0031
Loa Loa (eye worm) hypothetical protein 0.0051 0.0238 0.0238
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0078 0.042 0.0462
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0268 0.1704 0.1704
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0078 0.0078
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0027 0.0075 0.0036
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0028 0.0031
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0249 0.1576 0.1576
Schistosoma mansoni tyrosine kinase 0.0105 0.0603 0.0663
Brugia malayi SH2 domain containing protein 0.0016 0.0005 0.0005
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0146 0.0113
Echinococcus multilocularis cpg binding protein 0.0031 0.0106 0.0117
Echinococcus granulosus subfamily T1A non peptidase ue 0.0268 0.1704 0.1872
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0078 0.042 0.0462
Echinococcus granulosus axis inhibition protein axin 0.002 0.0028 0.0031
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0042 0.0046
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0268 0.1704 0.1872
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0107 0.0118
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0028 0.0031
Schistosoma mansoni neuropeptide receptor 0.0078 0.042 0.0462
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0421 0.2739 0.2739
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0656 0.4327 0.4751
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0107 0.0118
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0028 0.0031
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Onchocerca volvulus 0.0078 0.042 0.152
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.042 0.0462
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0152 0.0167
Schistosoma mansoni Tr4/Tr2 (homologue) 0.015 0.0911 0.1001
Schistosoma mansoni hypothetical protein 0.0035 0.0129 0.0142
Schistosoma mansoni rab6-interacting 0.002 0.0032 0.0035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0056 0.0061
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0027 0.0075 0.0083
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0054 0.0259 0.0284
Brugia malayi hypothetical protein 0.0068 0.0354 0.0354
Onchocerca volvulus 0.0037 0.0146 0.0514
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0105 0.0608 0.0663
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.015 0.0911 0.0911
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0078 0.042 0.0462
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0268 0.1704 0.1868
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0268 0.1704 0.1872
Loa Loa (eye worm) hypothetical protein 0.0249 0.1576 0.1576
Echinococcus granulosus neuropeptide FF receptor 2 0.0078 0.042 0.0462
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0268 0.1704 0.1872
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0078 0.042 0.042
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0078 0.042 0.0462
Loa Loa (eye worm) TK/EGFR protein kinase 0.0314 0.2015 0.2015
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.015 0.0911 0.1001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Brugia malayi protein-tyrosine kinase 0.0046 0.0208 0.0208
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0028 0.0031
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0068 0.0354 0.0384
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0268 0.1704 0.1868
Brugia malayi Nuclear hormone receptor family member nhr-3 0.015 0.0911 0.0911
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0399 0.0438
Echinococcus multilocularis epidermal growth factor receptor 0.0172 0.1055 0.1159
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0027 0.0075 0.0075
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0025 0.0025
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0181 0.0198
Loa Loa (eye worm) hypothetical protein 0.006 0.0299 0.0299
Trichomonas vaginalis glucosylceramidase, putative 0.0266 0.1691 0.1858
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0028 0.0031
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0268 0.1704 0.1872
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0078 0.042 0.042
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0199 0.124 0.124
Onchocerca volvulus 0.0027 0.0078 0.0267
Loa Loa (eye worm) G-protein coupled receptor 0.0078 0.042 0.042
Loa Loa (eye worm) hypothetical protein 0.0474 0.3098 0.3098
Brugia malayi proteasome subunit beta type 3 0.0268 0.1704 0.1704
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0032 0.0035
Schistosoma mansoni neuropeptide receptor 0.0078 0.042 0.0462
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0078 0.042 0.0462
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0146 0.016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.015 0.0911 0.0911
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0042 0.0046
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0129 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0138 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0064 0.007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus granulosus g protein coupled receptor 0.0078 0.042 0.0462
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0146 0.016
Echinococcus multilocularis somatostatin receptor 0.0078 0.042 0.0462
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0181 0.0193
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0268 0.1704 0.1872
Leishmania major proteasome beta-1 subunit, putative 0.0268 0.1704 0.1704
Brugia malayi Nuclear hormone receptor family member nhr-40 0.015 0.0911 0.0911
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0146 0.0113
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0146 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.042 0.0462
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0105 0.0608 0.0668
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0104 0.0104
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0005 0.0005
Brugia malayi nuclear hormone receptor 0.0071 0.0374 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0082 0.009
Echinococcus multilocularis dnaJ subfamily B 0.0421 0.2739 0.3009
Echinococcus granulosus neuropeptide receptor A26 0.0078 0.042 0.0462
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0041 0.0041
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0054 0.0259 0.0284
Giardia lamblia Proteasome subunit beta type 3 0.0268 0.1704 0.1836
Echinococcus multilocularis nuclear receptor nhr 48 0.0071 0.0374 0.0411
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0268 0.1704 0.1868
Loa Loa (eye worm) hypothetical protein 0.0203 0.1267 0.1267
Schistosoma mansoni glutathione synthetase 0.0027 0.0075 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.042 0.0462
Brugia malayi hypothetical protein 0.0078 0.042 0.042
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0268 0.1704 0.1704
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0128 0.014
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Echinococcus multilocularis conserved hypothetical protein 0.071 0.4693 0.5156
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.015 0.0911 0.0911
Brugia malayi Importin beta-1 subunit 0.0029 0.0093 0.0093
Echinococcus multilocularis serotonin transporter 0.0249 0.1576 0.1732
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0105 0.0608 0.0668
Loa Loa (eye worm) blistered cuticle protein 3 0.0027 0.0078 0.0078
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0268 0.1704 0.1704
Loa Loa (eye worm) hypothetical protein 0.1495 1 1
Treponema pallidum sodium- and chloride- dependent transporter 0.0249 0.1576 1
Schistosoma mansoni cpg binding protein 0.0031 0.0106 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-49 0.015 0.0911 0.0911
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0032 0.0035
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0046 0.0208 0.0228
Brugia malayi Cytochrome P450 family protein 0.0031 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0031 0.0107 0.0107
Loa Loa (eye worm) steroid hormone receptor 0.015 0.0911 0.0911
Schistosoma mansoni sodium/chloride dependent transporter 0.0249 0.1576 0.1732
Echinococcus granulosus peptide allatostatin:somatostatin 0.0078 0.042 0.0462
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0181 0.0181
Schistosoma mansoni coup transcription factor 0.015 0.0911 0.1001
Echinococcus granulosus epidermal growth factor receptor 0.0172 0.1055 0.1159
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.1073 0.1179
Mycobacterium ulcerans beta-lactamase 0.0037 0.0146 0.0113
Loa Loa (eye worm) hypothetical protein 0.0249 0.1576 0.1576
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0041 0.0039
Echinococcus multilocularis tyrosine protein kinase HCK 0.0038 0.0155 0.0171
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0042 0.0046
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0028 0.0028
Schistosoma mansoni amine GPCR 0.0078 0.042 0.0462
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0181 0.0198
Echinococcus multilocularis G protein coupled receptor 139 0.0078 0.042 0.0462
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0064 0.007
Schistosoma mansoni amine GPCR 0.0078 0.042 0.0462
Onchocerca volvulus 0.0078 0.042 0.152
Toxoplasma gondii peptidase, T1 family protein 0.0268 0.1704 0.1868
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0268 0.1704 0.1836
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Schistosoma mansoni regulator of G protein signaling 0.002 0.0028 0.0031
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0041 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.042 0.0462
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0027 0.0075 0.0077
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi hypothetical protein 0.002 0.0028 0.0028
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0028 0.0028
Brugia malayi PXA domain containing protein 0.002 0.0028 0.0028
Plasmodium vivax proteasome subunit beta type-6, putative 0.0268 0.1704 0.1868
Brugia malayi Furin-like cysteine rich region family protein 0.0314 0.2015 0.2015
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0027 0.0075 0.0083
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0208 0.0208
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0268 0.1704 0.1872
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0266 0.1691 0.1691
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0028 0.0031
Giardia lamblia Farnesyl diphosphate synthase 0.0105 0.0608 0.0626
Loa Loa (eye worm) hypothetical protein 0.015 0.0911 0.0911
Loa Loa (eye worm) TYRA-2 protein 0.0078 0.042 0.042
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0268 0.1704 0.1704
Schistosoma mansoni biogenic amine (5HT) receptor 0.0078 0.042 0.0462
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0004 0.0004
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0078 0.042 0.042
Schistosoma mansoni opsin-like receptor 0.0078 0.042 0.0462
Echinococcus multilocularis G-protein coupled receptor, putative 0.0078 0.042 0.0462
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0268 0.1704 0.1872
Loa Loa (eye worm) hypothetical protein 0.0022 0.0042 0.0042
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0078 0.042 0.0462
Giardia lamblia 20S proteasome alpha subunit 4 0.0268 0.1704 0.1836
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.0042 0.0042
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0105 0.0608 0.0668
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.015 0.0911 0.3314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0064 0.007
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0027 0.0075 0.0077
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0374 0.1352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0064 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0208 0.0228
Plasmodium falciparum multidrug resistance protein 1 0.0022 0.0042 0.004
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.0042 0.0041
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0105 0.0608 0.0608
Onchocerca volvulus 0.0037 0.0146 0.0514
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0042 0.0046
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0028 0.0028
Echinococcus granulosus g protein coupled receptor 0.0078 0.042 0.0462
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0042 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0071 0.0374 0.0374
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0181 0.0193
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1058 0.7048 0.7744
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0027 0.0075 0.0083

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 175 uM Dissociation constant against T4 lysozyme mutant L99A ChEMBL. 15916423
Kd (binding) = 175 uM Dissociation constant against T4 lysozyme mutant L99A ChEMBL. 15916423
Log BB (ADMET) = 0.37 logBB, log(C brain / C blood) ChEMBL. 8941388
Log C (ADMET) = -2.905 Toxicity determined using Tadpole Narcosis Test ChEMBL. 2033592
Log EC50 (ADMET) = 2.913 Toxicity determined using Microtox Test ChEMBL. 2033592
Log k' (ADMET) = 0.273 logD (measured by HPLC) (as log k') ChEMBL. 6167716
Log k' (ADMET) = 0.349 logD (measured by HPLC) (as log k') ChEMBL. 6167716
Log k' (ADMET) = 0.352 logD (measured by HPLC) (as log k') ChEMBL. 6167716
Log k' (ADMET) = 0.353 logD (measured by HPLC) (as log k') ChEMBL. 6167716
Log k' (ADMET) = 0.874 Partition coefficient (logD, measured by HPLC, log k') ChEMBL. 6167716
Log k' (ADMET) = 0.901 logD (measured by HPLC) (as log k') ChEMBL. 6167716
Log k' (ADMET) = 0.946 logD (measured by HPLC) (as log k') ChEMBL. 6167716
Log k' (ADMET) = 2.13 logD (measured by HPLC) (as log k') ChEMBL. 6167716
Log LC50 (ADMET) = -0.417 Toxicity determined using Golden Orfe Fish Test ChEMBL. 2033592
Log LC50 (ADMET) = 2.91 The toxicity of compound was determined using Konemann's Industrial Pollutants Toxicity Test ChEMBL. 2033592
Log PNalk = 2.29 Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system ChEMBL. 15857133
Log S = -1.64 Aqueous solubility ChEMBL. 10866370
logD (ADMET) = 2.13 Partition coefficient (logD7.4) ChEMBL. 6167716
logP (ADMET) = 2.13 Partition coefficient (logP) ChEMBL. 2993621
Potency (functional) = 0.004 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 794.3282 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

37 literature references were collected for this gene.

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