Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | esterase, putative | 0.0039 | 0.0156 | 0.0837 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0117 | 0.108 | 1 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0037 | 0.0139 | 0.0448 |
Schistosoma mansoni | methyltransferase-related | 0.0045 | 0.0227 | 0.1008 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0056 | 0.0352 | 0.2327 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.0578 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0227 | 0.1542 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0149 | 0.1453 | 0.4805 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0149 | 0.1453 | 0.5544 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0132 | 0.0487 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0039 | 0.0156 | 0.0578 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0099 | 0.0859 | 0.3701 |
Onchocerca volvulus | 0.0039 | 0.0156 | 0.0546 | |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.0156 | 0.0673 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0051 | 0.0302 | 0.1152 |
Onchocerca volvulus | 0.0056 | 0.0352 | 0.1231 | |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0158 | 0.1562 | 0.6731 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0117 | 0.108 | 0.4652 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0312 | 0.1897 |
Onchocerca volvulus | 0.0056 | 0.0352 | 0.1231 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0156 | 0.0837 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0158 | 0.1562 | 0.596 |
Echinococcus multilocularis | enteropeptidase | 0.0056 | 0.0352 | 0.0216 |
Brugia malayi | AMP-binding enzyme family protein | 0.0147 | 0.1426 | 0.4717 |
Echinococcus multilocularis | Mastin | 0.0056 | 0.0352 | 0.0216 |
Onchocerca volvulus | 0.0056 | 0.0352 | 0.1231 | |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0106 | 0.0948 | 0.5828 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0039 | 0.0156 | 0.0017 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0046 | 0.0238 | 0.1026 |
Brugia malayi | 6-phosphofructokinase | 0.0117 | 0.108 | 0.357 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0117 | 0.108 | 0.4652 |
Mycobacterium ulcerans | hypothetical protein | 0.0056 | 0.0352 | 0.1518 |
Onchocerca volvulus | 0.0052 | 0.0312 | 0.1089 | |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0039 | 0.0156 | 0.0596 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0117 | 0.108 | 1 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0223 | 0.2321 | 0.8855 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0039 | 0.0156 | 0.0673 |
Brugia malayi | 6-phosphofructokinase | 0.0117 | 0.108 | 0.357 |
Brugia malayi | Trypsin family protein | 0.0056 | 0.0352 | 0.1165 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0156 | 0.0837 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0158 | 0.1562 | 0.6731 |
Echinococcus granulosus | Mastin | 0.0056 | 0.0352 | 0.0831 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0056 | 0.0352 | 0.1165 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Onchocerca volvulus | 0.0039 | 0.0156 | 0.0546 | |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0248 | 0.2621 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0255 | 0.2703 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0255 | 0.2703 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0255 | 0.2703 | 0.26 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0156 | 0.0837 |
Loa Loa (eye worm) | beta-lactamase | 0.0039 | 0.0156 | 0.0578 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0037 | 0.0139 | 0.5 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0045 | 0.0227 | 0.0752 |
Echinococcus granulosus | enteropeptidase | 0.0056 | 0.0352 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.1255 | 0.4644 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0046 | 0.0238 | 0.0909 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.0332 | 0.1098 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0117 | 0.108 | 0.3995 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0223 | 0.2321 | 1 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0037 | 0.0139 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.0578 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.0047 | 0.025 | 0.1077 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0156 | 0.0258 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0037 | 0.0139 | 0.06 |
Mycobacterium ulcerans | thioesterase TesA | 0.0124 | 0.1161 | 0.5001 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.0578 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0039 | 0.0156 | 0.0596 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0041 | 0.0177 | 0.1641 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0117 | 0.108 | 1 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0056 | 0.0352 | 0.0216 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0158 | 0.1562 | 0.596 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0117 | 0.108 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0039 | 0.0156 | 0.0596 |
Mycobacterium ulcerans | polyketide synthase | 0.0149 | 0.1453 | 0.6261 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0117 | 0.108 | 1 |
Onchocerca volvulus | 0.0039 | 0.0156 | 0.0546 | |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0097 | 0.0837 | 0.5091 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0124 | 0.1161 | 0.5001 |
Brugia malayi | phosphofructokinase | 0.0117 | 0.108 | 0.357 |
Mycobacterium leprae | conserved hypothetical protein | 0.0039 | 0.0156 | 0.0673 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0047 | 0.025 | 0.0953 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.0578 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0117 | 0.108 | 1 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0149 | 0.1453 | 0.6261 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0145 | 0.1399 | 0.5339 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.0332 | 0.1098 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0158 | 0.1562 | 0.6731 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0117 | 0.108 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0132 | 0.0436 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0056 | 0.0352 | 0.0216 |
Brugia malayi | Trypsin family protein | 0.0056 | 0.0352 | 0.1165 |
Brugia malayi | Trypsin family protein | 0.0056 | 0.0352 | 0.1165 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0159 | 0.1574 | 1 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0223 | 0.2321 | 0.8855 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0682 | 0.2522 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0149 | 0.1453 | 0.6261 |
Onchocerca volvulus | 0.0267 | 0.2841 | 0.9928 | |
Schistosoma mansoni | survival motor neuron protein | 0.0052 | 0.0312 | 0.1897 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0223 | 0.2321 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0117 | 0.108 | 1 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0149 | 0.1453 | 0.6261 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0085 | 0.0696 | 0.2656 |
Brugia malayi | hypothetical protein | 0.0255 | 0.2703 | 0.8938 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0145 | 0.1399 | 0.5339 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.012 | 0.111 | 0.4784 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0056 | 0.0352 | 0.0216 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0037 | 0.0139 | 0.0515 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0117 | 0.108 | 1 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0147 | 0.1426 | 0.5442 |
Leishmania major | hypothetical protein, conserved | 0.0045 | 0.0227 | 0.2105 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.012 | 0.111 | 0.4784 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0037 | 0.0139 | 0.7977 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0047 | 0.025 | 0.1077 |
Onchocerca volvulus | 0.0056 | 0.0352 | 0.1231 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0352 | 0.1303 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0039 | 0.0156 | 0.0596 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0352 | 0.1303 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0056 | 0.0352 | 0.0831 |
Loa Loa (eye worm) | acyl carrier protein | 0.0069 | 0.0506 | 0.187 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0037 | 0.0139 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0056 | 0.0352 | 0.0831 |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.0352 | 0.2327 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0158 | 0.1562 | 0.6731 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0117 | 0.108 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0156 | 0.0181 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0158 | 0.1562 | 0.6731 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0045 | 0.0227 | 0.0867 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0117 | 0.108 | 0.3995 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0283 | 0.3024 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0117 | 0.108 | 0.0954 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.0156 | 0.1447 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0099 | 0.0859 | 0.3701 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0332 | 0.1229 |
Onchocerca volvulus | 0.0147 | 0.1426 | 0.4985 | |
Onchocerca volvulus | Huntingtin homolog | 0.0132 | 0.1255 | 0.4387 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0352 | 0.1303 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0149 | 0.1453 | 0.5544 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0156 | 0.0517 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0352 | 0.1303 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0056 | 0.0352 | 0.0831 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0039 | 0.0156 | 0.0067 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0076 | 0.0598 | 0.35 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0352 | 0.1303 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0039 | 0.0156 | 0.0673 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.012 | 0.111 | 0.4784 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0037 | 0.0139 | 0.046 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0124 | 0.1161 | 0.4428 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0156 | 0.0596 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0156 | 0.0837 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0039 | 0.0156 | 0.0596 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0156 | 0.0837 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0052 | 0.0312 | 0.103 |
Mycobacterium leprae | Probable lipase LipE | 0.0039 | 0.0156 | 0.0673 |
Mycobacterium ulcerans | lipase LipD | 0.0039 | 0.0156 | 0.0673 |
Loa Loa (eye worm) | fatty acid synthase | 0.0147 | 0.143 | 0.529 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0352 | 0.1303 |
Mycobacterium tuberculosis | Conserved protein | 0.0045 | 0.0227 | 0.0867 |
Loa Loa (eye worm) | hypothetical protein | 0.0252 | 0.2658 | 0.9835 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0037 | 0.0139 | 0.06 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0117 | 0.108 | 1 |
Brugia malayi | beta-lactamase | 0.0039 | 0.0156 | 0.0517 |
Mycobacterium ulcerans | thioesterase | 0.0124 | 0.1161 | 0.5001 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0156 | 0.0181 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Toxoplasma gondii | ABC1 family protein | 0.0039 | 0.0156 | 0.0561 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0149 | 0.1453 | 0.5544 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0149 | 0.1453 | 0.6261 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0037 | 0.0139 | 0.06 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0037 | 0.0139 | 0.1289 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0056 | 0.0352 | 0.0216 |
Giardia lamblia | Methyltransferase like 2 | 0.0045 | 0.0227 | 1 |
Mycobacterium ulcerans | polyketide synthase | 0.0158 | 0.1562 | 0.6731 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.0332 | 0.1229 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0147 | 0.1426 | 0.5277 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0122 | 0.1133 | 0.4325 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0117 | 0.108 | 0.4119 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0056 | 0.0352 | 0.1165 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0149 | 0.1453 | 0.6261 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0156 | 0.0258 |
Brugia malayi | hypothetical protein | 0.0056 | 0.0352 | 0.1165 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0032 | 0.0072 | 0.0666 |
Plasmodium vivax | hypothetical protein, conserved | 0.0039 | 0.0156 | 1 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0158 | 0.1562 | 0.596 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0039 | 0.0156 | 0.0596 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0117 | 0.108 | 1 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0056 | 0.0352 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.0578 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.006 | 0.0408 | 0.1558 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Brugia malayi | Trypsin family protein | 0.0056 | 0.0352 | 0.1165 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.025 | 0.0828 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0039 | 0.0156 | 0.0517 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0037 | 0.0139 | 0.0078 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0107 | 0.0959 | 0.3659 |
Loa Loa (eye worm) | phosphofructokinase | 0.0117 | 0.108 | 0.3995 |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.0352 | 0.2327 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0149 | 0.1453 | 0.6261 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Onchocerca volvulus | Huntingtin homolog | 0.0132 | 0.1255 | 0.4387 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0352 | 0.1303 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.1255 | 0.4644 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0156 | 0.0596 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0099 | 0.0859 | 0.3701 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0117 | 0.108 | 1 |
Onchocerca volvulus | 0.0056 | 0.0352 | 0.1231 | |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0156 | 0.0578 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0156 | 0.0596 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0039 | 0.0156 | 0.0596 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0036 | 0.0127 | 0.0486 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0156 | 0.0517 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0056 | 0.0352 | 0.2327 |
Onchocerca volvulus | 0.0056 | 0.0352 | 0.1231 | |
Echinococcus granulosus | 6 phosphofructokinase | 0.0117 | 0.108 | 0.3669 |
Brugia malayi | hypothetical protein | 0.0132 | 0.1255 | 0.4151 |
Mycobacterium ulcerans | beta-lactamase | 0.0039 | 0.0156 | 0.0673 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.0156 | 0.0181 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0269 | 0.2861 | 1 |
Loa Loa (eye worm) | trypsin family protein | 0.0056 | 0.0352 | 0.1303 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.712 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.