Detailed information for compound 1603136

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 365.427 | Formula: C15H15N3O4S2
  • H donors: 2 H acceptors: 3 LogP: 1.93 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1c(/N=C/C2C(=O)NC(=S)NC2=O)sc2c1CCC2
  • InChi: 1S/C15H15N3O4S2/c1-2-22-14(21)10-7-4-3-5-9(7)24-13(10)16-6-8-11(19)17-15(23)18-12(8)20/h6,8H,2-5H2,1H3,(H2,17,18,19,20,23)/b16-6+
  • InChiKey: PPSLRDNSYWDYKX-OMCISZLKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Starlite/ChEMBL No references
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Starlite/ChEMBL No references
Homo sapiens tyrosyl-DNA phosphodiesterase 1 Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Trypanosoma brucei hypothetical protein, conserved Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens RAN, member RAS oncogene family No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni tyrosyl-DNA phosphodiesterase Get druggable targets OG5_129037 All targets in OG5_129037
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum tyrosyl-DNA phodphodiesterase 1 (tdp1) Get druggable targets OG5_129037 All targets in OG5_129037
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma brucei hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania infantum hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis tyrosyl-DNA phosphodiesterase, putative;with=GeneDB:LinJ33_V3.3210 Get druggable targets OG5_129037 All targets in OG5_129037
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum tyrosyl-DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major tyrosyl-DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis transcription factor Dp 1 Get druggable targets OG5_129037 All targets in OG5_129037
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative Get druggable targets OG5_129037 All targets in OG5_129037
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K00142 aminoadipate-semialdehyde dehydrogenase [EC1.2.1.31], putative Get druggable targets OG5_129301 All targets in OG5_129301
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana tyrosyl-DNA phosphodiesterase-like protein Get druggable targets OG5_129037 All targets in OG5_129037
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_129037 All targets in OG5_129037
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus multilocularis L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani tyrosyl-DNA phosphodiesterase-like protein Get druggable targets OG5_129037 All targets in OG5_129037
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense HpcH/HpaI aldolase/citrate lyase family, putative Get druggable targets OG5_146801 All targets in OG5_146801
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma japonicum expressed protein Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania donovani HpcH/HpaI aldolase/citrate lyase family, putative Get druggable targets OG5_146801 All targets in OG5_146801
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Cryptosporidium parvum phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trypanosoma brucei gambiense tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K01113 phosphodiesterase/alkaline phosphatase D [EC3.1.4.1], putative Get druggable targets OG5_129037 All targets in OG5_129037
Onchocerca volvulus Get druggable targets OG5_129301 All targets in OG5_129301
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Cryptosporidium hominis proteinx0005 Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein Get druggable targets OG5_129037 All targets in OG5_129037
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Trypanosoma brucei gambiense hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus transcription factor Dp 1 Get druggable targets OG5_129037 All targets in OG5_129037
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania braziliensis hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase Get druggable targets OG5_129301 All targets in OG5_129301
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium berghei dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 26.9 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Leishmania donovani acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Entamoeba histolytica hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 198 aa 28.3 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.3 %
Onchocerca volvulus 4'-phosphopantetheinyl transferase ffp   224 aa 186 aa 26.3 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 529 aa 31.8 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Plasmodium falciparum thioredoxin reductase Thioredoxin reductase 1, cytoplasmic   499 aa 511 aa 45.2 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Trichomonas vaginalis conserved hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 197 aa 22.3 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.5 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.2 %
Leishmania braziliensis dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 488 aa 21.9 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.9 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.5 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 539 aa 22.3 %
Plasmodium falciparum glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 500 aa 32.2 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 519 aa 23.7 %
Leishmania infantum acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin reductase 1, cytoplasmic   499 aa 506 aa 23.7 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.2 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin reductase 1, cytoplasmic   499 aa 464 aa 24.8 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Leishmania braziliensis 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 450 aa 25.6 %
Leishmania braziliensis acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 22.8 %
Trypanosoma brucei dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.4 %
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 454 aa 25.3 %
Leishmania mexicana acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 24.4 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Neospora caninum glutathione reductase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 32.7 %
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 460 aa 25.4 %
Leishmania donovani dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.6 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, point mutation,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.3 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 540 aa 23.3 %
Leishmania mexicana 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 452 aa 25.7 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.5 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Onchocerca volvulus Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 57.3 %
Neospora caninum hypothetical protein Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.0 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.3 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Leishmania infantum dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Leishmania major acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 518 aa 24.9 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 462 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis protein kinase atn1, putative 0.0144 0.1637 0.3926
Onchocerca volvulus 0.0206 0.2381 0.5518
Brugia malayi SH2 domain containing protein 0.035 0.4133 0.9578
Echinococcus granulosus suppressor of cytokine signaling 6 0.0206 0.2381 0.2381
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0318 0.0736
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis tensin 0.0206 0.2381 0.2381
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0144 0.1637 0.1637
Entamoeba histolytica ankyrin repeat protein 0.0144 0.1637 0.3926
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0318 0.194
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.035 0.4133 0.4133
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Giardia lamblia Protein 21.1 0.0144 0.1637 0.3926
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus granulosus tyrosine kinase 0.035 0.4133 0.4133
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0144 0.1637 0.3794
Onchocerca volvulus 0.0206 0.2381 0.5518
Brugia malayi Variant SH3 domain containing protein 0.0206 0.2381 0.5518
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0308 0.0308
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.1637 0.3723
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0014 0.0032
Echinococcus granulosus SH2 domain containing protein 7 0.0206 0.2381 0.2381
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0144 0.1637 0.5451
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Echinococcus granulosus tyrosine protein kinase Fps85D 0.035 0.4133 0.4133
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0228 0.0547
Entamoeba histolytica receptor protein kinase, putative 0.0144 0.1637 0.3926
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Echinococcus granulosus growth factor receptor bound protein 2 0.0206 0.2381 0.2381
Brugia malayi Protein kinase domain containing protein 0.035 0.4133 0.9578
Entamoeba histolytica ankyrin repeat protein 0.0144 0.1637 0.3926
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0206 0.2381 0.2381
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.4397 1
Echinococcus granulosus tyrosine protein kinase csk 0.0144 0.1637 0.1637
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0144 0.1637 0.1637
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0318 0.1057
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0144 0.1637 0.3794
Onchocerca volvulus 0.0144 0.1637 0.3794
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) RGC/RGC protein kinase 0.0144 0.1637 0.3723
Echinococcus granulosus c src tyrosine kinase 0.035 0.4133 0.4133
Brugia malayi SH2 domain containing protein 0.0206 0.2381 0.5518
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0244 0.1235
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Echinococcus multilocularis ephrin type A receptor 4 A 0.0144 0.1637 0.1637
Echinococcus multilocularis tyrosine protein kinase Fyn 0.035 0.4133 0.4133
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4169 1
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Schistosoma mansoni tyrosine kinase 0.035 0.4133 0.4133
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis tyrosine protein kinase 0.0144 0.1637 0.1637
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.035 0.4133 0.4133
Echinococcus granulosus tyrosine protein kinase pr2 0.0144 0.1637 0.1637
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.1637 0.3723
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0206 0.2381 0.2381
Echinococcus multilocularis tyrosine protein kinase Blk 0.035 0.4133 0.4133
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0206 0.2381 0.2381
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0775 0.4736
Onchocerca volvulus 0.0206 0.2381 0.5518
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Brugia malayi hypothetical protein 0.035 0.4133 0.9578
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Plasmodium vivax tyrosine kinase-like protein, putative 0.0144 0.1637 1
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0015 0.0035
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.035 0.4133 0.4133
Brugia malayi STAT protein, DNA binding domain containing protein 0.0206 0.2381 0.5518
Entamoeba histolytica tyrosin kinase, putative 0.0144 0.1637 0.3926
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0318 0.194
Echinococcus multilocularis SHC transforming protein 3 0.0206 0.2381 0.2381
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0144 0.1637 0.1637
Echinococcus multilocularis protein kinase 0.0144 0.1637 0.1637
Echinococcus multilocularis c src tyrosine kinase 0.035 0.4133 0.4133
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0318 0.0762
Echinococcus multilocularis protein kinase 0.0144 0.1637 0.1637
Brugia malayi SRC-1 0.035 0.4133 0.9578
Echinococcus multilocularis tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus granulosus tyrosine protein kinase Lyn 0.035 0.4133 0.4133
Schistosoma mansoni ran 0.0026 0.0196 0.0196
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0775 0.0775
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.035 0.4133 0.4133
Echinococcus multilocularis activin receptor type 0.0144 0.1637 0.1637
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.0228 0.718
Plasmodium falciparum glutathione reductase 0.0036 0.0318 0.194
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Trichomonas vaginalis TK family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0144 0.1637 0.1637
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0144 0.1637 0.3723
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0144 0.1637 0.1637
Loa Loa (eye worm) SH2 domain-containing protein 0.0206 0.2381 0.5415
Loa Loa (eye worm) TK/INSR protein kinase 0.0144 0.1637 0.3723
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Leishmania major importin beta-1 subunit, putative 0.0028 0.0228 0.0759
Echinococcus granulosus citrate lyase subunit beta protein 0.003 0.0244 0.0244
Echinococcus granulosus tyrosine protein kinase Fyn 0.035 0.4133 0.4133
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis tyrosine protein kinase ABL1 0.035 0.4133 0.4133
Echinococcus granulosus tyrosine protein kinase Blk 0.035 0.4133 0.4133
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Schistosoma mansoni suppressor of cytokine signaling 0.0206 0.2381 0.2381
Entamoeba histolytica hypothetical protein 0.0028 0.0228 0.0547
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0144 0.1637 0.3794
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0196 0.0654
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0206 0.2381 0.2381
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0206 0.2381 0.2381
Echinococcus granulosus dnaJ subfamily B 0.0494 0.5881 0.5881
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0144 0.1637 1
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus granulosus NCK adaptor protein 0.0206 0.2381 0.2381
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0318 0.1057
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Onchocerca volvulus 0.035 0.4133 0.9578
Loa Loa (eye worm) TK/Met protein kinase 0.0144 0.1637 0.3723
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Loa Loa (eye worm) TK/ALK protein kinase 0.0144 0.1637 0.3723
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Schistosoma mansoni vav2 0.0206 0.2381 0.2381
Schistosoma mansoni tyrosine kinase 0.035 0.4133 0.4133
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0318 0.1057
Echinococcus multilocularis cpg binding protein 0.0037 0.033 0.033
Echinococcus multilocularis growth factor receptor bound protein 2 0.0206 0.2381 0.2381
Onchocerca volvulus 0.035 0.4133 0.9578
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0318 0.1057
Schistosoma mansoni hypothetical protein 0.0372 0.4397 0.4397
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0206 0.2381 0.2381
Onchocerca volvulus 0.01 0.1104 0.2558
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4169 1
Onchocerca volvulus 0.0365 0.4315 1
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0318 0.0318
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0144 0.1637 0.1637
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0306 0.0696
Onchocerca volvulus 0.035 0.4133 0.9578
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0206 0.2381 0.2381
Loa Loa (eye worm) hypothetical protein 0.01 0.1104 0.251
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4169 1
Plasmodium vivax protein kinase, putative 0.0144 0.1637 1
Echinococcus granulosus expressed conserved protein 0.0206 0.2381 0.2381
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0853 0.2839
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Leishmania major trypanothione reductase 0.0103 0.1133 0.3772
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0144 0.1637 0.1637
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0318 0.0762
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Echinococcus granulosus cpg binding protein 0.0037 0.033 0.033
Echinococcus granulosus tyrosine protein kinase Fyn 0.035 0.4133 0.4133
Giardia lamblia Kinase, NEK 0.0144 0.1637 0.3926
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0228 0.1393
Onchocerca volvulus Tyrosine kinase homolog 0.0144 0.1637 0.3794
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0318 0.1057
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0144 0.1637 0.3926
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0318 0.1042
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) TK/ABL protein kinase 0.035 0.4133 0.9399
Leishmania major hypothetical protein, conserved 0.0257 0.3003 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0318 0.1057
Entamoeba histolytica protein kinase, putative 0.0206 0.2381 0.5711
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.1637 0.3926
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0556 0.1288
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Loa Loa (eye worm) TK/RYK protein kinase 0.0144 0.1637 0.3723
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0206 0.2381 0.5518
Echinococcus multilocularis SH2 motif 0.0206 0.2381 0.2381
Schistosoma mansoni microtubule-associated protein tau 0.0833 1 1
Brugia malayi Raf kinase 0.0144 0.1637 0.3794
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.1637 0.3926
Echinococcus multilocularis thioredoxin glutathione reductase 0.0103 0.114 0.114
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0206 0.2381 0.2381
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Plasmodium vivax glutathione reductase, putative 0.0103 0.1133 0.692
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0775 0.3919
Echinococcus multilocularis SH2 domain containing protein 7 0.0206 0.2381 0.2381
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0206 0.2381 0.5415
Echinococcus multilocularis activated cdc42 kinase 1 0.0144 0.1637 0.1637
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.035 0.4133 0.4133
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0775 0.2543
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0234 0.2731 0.8958
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Loa Loa (eye worm) TK/EPH protein kinase 0.0144 0.1637 0.3723
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0144 0.1637 0.1637
Schistosoma mansoni hypothetical protein 0.0206 0.2381 0.2381
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis tensin 0.0206 0.2381 0.2381
Echinococcus multilocularis tyrosine protein kinase Fyn 0.035 0.4133 0.4133
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0144 0.1637 0.3723
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0144 0.1637 0.1637
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Schistosoma mansoni SH2A 0.0206 0.2381 0.2381
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Brugia malayi integrin-linked kinase 0.0144 0.1637 0.3794
Mycobacterium tuberculosis Probable dehydrogenase 0.0234 0.2731 0.8958
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0244 0.0814
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0318 1
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Echinococcus granulosus natriuretic peptide receptor 1 0.0144 0.1637 0.1637
Loa Loa (eye worm) serine/threonine protein kinase 0.0144 0.1637 0.3723
Echinococcus granulosus retinal guanylyl cyclase 2 0.0144 0.1637 0.1637
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0144 0.1637 0.1637
Plasmodium falciparum importin beta, putative 0.0035 0.0308 0.1881
Brugia malayi cytokine inducible SH2-containing protein 5 0.0206 0.2381 0.5518
Loa Loa (eye worm) TK protein kinase 0.0144 0.1637 0.3723
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0318 0.0762
Schistosoma mansoni tyrosine protein kinase 0.0144 0.1637 0.1637
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0775 0.2581
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0203 0.047
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0144 0.1637 0.3723
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0144 0.1637 0.5451
Entamoeba histolytica hypothetical protein 0.0028 0.0228 0.0547
Onchocerca volvulus 0.0144 0.1637 0.3794
Loa Loa (eye worm) thioredoxin reductase 0.0103 0.1133 0.2576
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0556 0.0556
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Entamoeba histolytica serine/threonine kinase, putative 0.0144 0.1637 0.3926
Echinococcus granulosus tyrosine protein kinase Src42A 0.035 0.4133 0.4133
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0318 0.1605
Onchocerca volvulus 0.0206 0.2381 0.5518
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0318 0.1057
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Echinococcus granulosus protein kinase 0.0144 0.1637 0.1637
Entamoeba histolytica SH2 domain containing protein 0.0206 0.2381 0.5711
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.4169 1
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Onchocerca volvulus 0.0206 0.2381 0.5518
Onchocerca volvulus 0.035 0.4133 0.9578
Echinococcus multilocularis microtubule associated protein 2 0.0833 1 1
Plasmodium vivax thioredoxin reductase, putative 0.0103 0.1133 0.692
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis tyrosine protein kinase pr2 0.0144 0.1637 0.1637
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0144 0.1637 0.1637
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.1637 0.3723
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Onchocerca volvulus 0.035 0.4133 0.9578
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0144 0.1637 0.3926
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.4169 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0144 0.1637 0.3723
Mycobacterium ulcerans hypothetical protein 0.003 0.0244 0.1235
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0144 0.1637 0.3794
Loa Loa (eye worm) hypothetical protein 0.0035 0.0308 0.07
Echinococcus multilocularis citrate lyase subunit beta protein 0.003 0.0244 0.0244
Echinococcus multilocularis tyrosine protein kinase csk 0.0144 0.1637 0.1637
Loa Loa (eye worm) TK protein kinase 0.035 0.4133 0.9399
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.0853 0.1976
Echinococcus multilocularis tyrosine protein kinase Abl 0.035 0.4133 0.4133
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0144 0.1637 0.1637
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0234 0.2731 0.8958
Brugia malayi RhoGAP domain containing protein 0.0206 0.2381 0.5518
Toxoplasma gondii STE kinase 0.0144 0.1637 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0261 0.3049 1
Leishmania major protein kinase, putative 0.0144 0.1637 0.5451
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0206 0.2381 0.2381
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Schistosoma mansoni tensin 0.0206 0.2381 0.2381
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0206 0.2381 0.5415
Schistosoma mansoni tyrosine kinase 0.035 0.4133 0.4133
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0318 0.1057
Trichomonas vaginalis STE family protein kinase 0.0144 0.1637 0.3926
Echinococcus granulosus tyrosine protein kinase Btk29A 0.035 0.4133 0.4133
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0206 0.2381 0.5415
Echinococcus granulosus ephrin type A receptor 4 A 0.0144 0.1637 0.1637
Loa Loa (eye worm) hypothetical protein 0.0365 0.4315 0.9813
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0318 0.194
Loa Loa (eye worm) RGC/RGC protein kinase 0.0144 0.1637 0.3723
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0144 0.1637 0.3723
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0318 0.1057
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0445 0.0445
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.1637 0.3723
Echinococcus multilocularis tyrosine protein kinase Src42A 0.035 0.4133 0.4133
Mycobacterium tuberculosis Conserved protein 0.003 0.0244 0.0801
Leishmania major hypothetical protein, conserved 0.0144 0.1637 0.5451
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0206 0.2381 0.2381
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.1104 0.1104
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0228 0.0547
Entamoeba histolytica tyrosin kinase, putative 0.0144 0.1637 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0144 0.1637 0.1637
Loa Loa (eye worm) glutathione reductase 0.0103 0.1133 0.2576
Echinococcus multilocularis transfer RNA-Thr 0.0144 0.1637 0.1637
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0206 0.2381 0.2381
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0206 0.2381 0.2381
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.1637 0.3926
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.1104 0.1104
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0196 0.1199
Echinococcus multilocularis tyrosine protein kinase csk 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis SH2 motif 0.0206 0.2381 0.2381
Brugia malayi hypothetical protein 0.0365 0.4315 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.4169 1
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Loa Loa (eye worm) SRC-1 0.035 0.4133 0.9399
Onchocerca volvulus 0.0144 0.1637 0.3794
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0206 0.2381 0.2381
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0261 0.3049 1
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0308 0.1025
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0206 0.2381 0.5415
Brugia malayi RNA, U transporter 1 0.0099 0.1087 0.2519
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4169 1
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.1637 0.3723
Entamoeba histolytica cysteine surface protein, putative 0.0144 0.1637 0.3926
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0228 0.0748
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.035 0.4133 0.4133
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.0853 0.0853
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0144 0.1637 0.3926
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.0853 0.0853
Echinococcus granulosus retinal guanylyl cyclase 2 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus granulosus retinal guanylyl cyclase 2 0.0144 0.1637 0.1637
Echinococcus granulosus importin subunit beta 1 0.0035 0.0308 0.0308
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.1978 0.6488
Schistosoma mansoni ran 0.0026 0.0196 0.0196
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.1637 0.3723
Trypanosoma brucei protein kinase, putative 0.0144 0.1637 0.5451
Plasmodium falciparum tyrosine kinase-like protein 0.0144 0.1637 1
Echinococcus multilocularis insulin receptor 0.0144 0.1637 0.1637
Echinococcus granulosus integrin linked protein kinase 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0318 1
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Schistosoma mansoni serine/threonine RGC 0.0144 0.1637 0.1637
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0144 0.1637 0.1637
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0318 0.194
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.035 0.4133 0.4133
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Brugia malayi Guanylyl cyclase protein 23 0.0144 0.1637 0.3794
Brugia malayi SH2 domain containing protein 0.0206 0.2381 0.5518
Echinococcus granulosus tyrosine protein kinase Srms 0.035 0.4133 0.4133
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0318 0.194
Loa Loa (eye worm) TK protein kinase 0.0144 0.1637 0.3723
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0196 0.1199
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Brugia malayi Thioredoxin reductase 0.0103 0.1133 0.2625
Plasmodium falciparum protein kinase, putative 0.0144 0.1637 1
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Echinococcus multilocularis receptor type guanylyl cyclase 0.0144 0.1637 0.1637
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Onchocerca volvulus 0.035 0.4133 0.9578
Echinococcus granulosus tyrosine protein kinase Src64B 0.035 0.4133 0.4133
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0144 0.1637 0.1637
Giardia lamblia Kinase, NEK 0.0144 0.1637 0.3926
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Echinococcus multilocularis tyrosine protein kinase Fgr 0.035 0.4133 0.4133
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0244 0.1235
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Brugia malayi SH2 domain containing protein 0.0206 0.2381 0.5518
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0318 0.1057
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) TK protein kinase 0.0144 0.1637 0.3723
Schistosoma mansoni tensin-related 0.0206 0.2381 0.2381
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0775 0.0775
Mycobacterium tuberculosis Probable reductase 0.0234 0.2731 0.8958
Brugia malayi SH2 domain containing protein 0.0206 0.2381 0.5518
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0196 0.0196
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0144 0.1637 0.3794
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.0853 0.2046
Loa Loa (eye worm) TK protein kinase 0.0144 0.1637 0.3723
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Echinococcus multilocularis tyrosine protein kinase csk 0.0144 0.1637 0.1637
Onchocerca volvulus 0.0144 0.1637 0.3794
Schistosoma mansoni suppressor of cytokine signaling 0.0206 0.2381 0.2381
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus granulosus snurportin 1 0.0372 0.4397 0.4397
Echinococcus granulosus tyrosine protein kinase HCK 0.0144 0.1637 0.1637
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0144 0.1637 0.3926
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Toxoplasma gondii protein kinase domain-containing protein 0.0144 0.1637 1
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.1637 0.3723
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0853 0.2839
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0196 0.0654
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4169 1
Toxoplasma gondii protein kinase 0.0144 0.1637 1
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.1637 0.1637
Plasmodium falciparum protein kinase, putative 0.0144 0.1637 1
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus granulosus activin receptor type 0.0144 0.1637 0.1637
Schistosoma mansoni hypothetical protein 0.0206 0.2381 0.2381
Loa Loa (eye worm) TK/ROR protein kinase 0.0144 0.1637 0.3723
Brugia malayi C-terminal src kinase protein 1 0.0144 0.1637 0.3794
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Echinococcus granulosus tyrosine protein kinase 0.0144 0.1637 0.1637
Plasmodium falciparum thioredoxin reductase 0.0036 0.0318 0.194
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Brugia malayi SH2 domain containing protein 0.0206 0.2381 0.5518
Echinococcus granulosus activated cdc42 kinase 1 0.0144 0.1637 0.1637
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0775 0.3919
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Schistosoma mansoni importin beta-1 0.0035 0.0308 0.0308
Loa Loa (eye worm) TK protein kinase 0.0144 0.1637 0.3723
Schistosoma mansoni adapter molecule crk 0.0206 0.2381 0.2381
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0196 0.0654
Schistosoma mansoni tensin-related 0.0206 0.2381 0.2381
Plasmodium falciparum glutathione reductase 0.0103 0.1133 0.692
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0144 0.1637 0.1637
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0244 0.0814
Echinococcus multilocularis tyrosine protein kinase HCK 0.0144 0.1637 0.1637
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0144 0.1637 0.3723
Entamoeba histolytica serine/threonine kinase, putative 0.0144 0.1637 0.3926
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.1637 0.1637
Echinococcus granulosus SH2 motif 0.0206 0.2381 0.2381
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.1104 0.1104
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Schistosoma mansoni protein tyrosine kinase 0.0144 0.1637 0.1637
Schistosoma mansoni GTPase activating protein 0.0206 0.2381 0.2381
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0556 0.0556
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0228 0.0547
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.1637 0.3926
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0144 0.1637 0.1637
Mycobacterium tuberculosis Probable oxidoreductase 0.0261 0.3049 1
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis integrin linked protein kinase 0.0144 0.1637 0.1637
Echinococcus multilocularis tyrosine protein kinase Src64B 0.035 0.4133 0.4133
Echinococcus multilocularis natriuretic peptide receptor 1 0.0144 0.1637 0.1637
Echinococcus granulosus hypothetical protein 0.0206 0.2381 0.2381
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Brugia malayi protein-tyrosine kinase 0.035 0.4133 0.9578
Echinococcus multilocularis protein tyrosine kinase 0.0144 0.1637 0.1637
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Schistosoma mansoni hypothetical protein 0.0494 0.5881 0.5881
Toxoplasma gondii thioredoxin reductase 0.0103 0.1133 0.692
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Schistosoma mansoni hypothetical protein 0.0144 0.1637 0.1637
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Entamoeba histolytica serine/threonine kinase, putative 0.0144 0.1637 0.3926
Echinococcus granulosus tyrosine protein kinase csk 0.0144 0.1637 0.1637
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus granulosus epidermal growth factor receptor 0.0144 0.1637 0.1637
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Trypanosoma cruzi trypanothione reductase, putative 0.0103 0.1133 0.3772
Echinococcus granulosus tyrosine protein kinase Fyn 0.035 0.4133 0.4133
Loa Loa (eye worm) TK protein kinase 0.0144 0.1637 0.3723
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0778 0.0778
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Brugia malayi bone morphogenetic protein type 1 receptor 0.0144 0.1637 0.3794
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0206 0.2381 0.2381
Schistosoma mansoni growth factor receptor-bound protein 0.0206 0.2381 0.2381
Brugia malayi Protein kinase domain containing protein 0.035 0.4133 0.9578
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0556 0.0556
Entamoeba histolytica receptor protein kinase, putative 0.0144 0.1637 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Onchocerca volvulus 0.0144 0.1637 0.3794
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.1637 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.035 0.4133 0.4133
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.1978 0.6488
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0234 0.2731 0.8958
Brugia malayi Protein kinase domain containing protein 0.035 0.4133 0.9578
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0206 0.2381 0.2381
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.035 0.4133 0.4133
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0206 0.2381 0.2381
Echinococcus multilocularis tyrosine protein kinase csk 0.0144 0.1637 0.1637
Schistosoma mansoni tyrosine kinase 0.035 0.4133 0.4133
Brugia malayi glutathione reductase 0.0103 0.1133 0.2625
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Schistosoma mansoni growth factor receptor-bound protein 0.0206 0.2381 0.2381
Schistosoma mansoni nck2/grb4 0.0206 0.2381 0.2381
Brugia malayi Variant SH3 domain containing protein 0.0206 0.2381 0.5518
Onchocerca volvulus 0.0206 0.2381 0.5518
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0775 0.0775
Echinococcus granulosus SHC transforming protein 3 0.0206 0.2381 0.2381
Brugia malayi Variant SH3 domain containing protein 0.0206 0.2381 0.5518
Brugia malayi CXXC zinc finger family protein 0.0035 0.0306 0.071
Loa Loa (eye worm) TK protein kinase 0.0144 0.1637 0.3723
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0196 0.0446
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0144 0.1637 0.3794
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Brugia malayi Receptor family ligand binding region containing protein 0.0144 0.1637 0.3794
Echinococcus multilocularis tyrosine protein kinase Srms 0.035 0.4133 0.4133
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0206 0.2381 0.5518
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.1104 0.2558
Loa Loa (eye worm) TK protein kinase 0.0144 0.1637 0.3723
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Schistosoma mansoni cpg binding protein 0.0037 0.033 0.033
Loa Loa (eye worm) SH2 domain-containing protein 0.0206 0.2381 0.5415
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0318 0.1057
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0775 0.3919
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus granulosus signal transduction protein lnk realted 0.0206 0.2381 0.2381
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Echinococcus multilocularis epidermal growth factor receptor 0.0144 0.1637 0.1637
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0556 0.0556
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0234 0.2731 0.8958
Echinococcus granulosus tyrosine kinase 0.035 0.4133 0.4133
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0318 0.1057
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0144 0.1637 0.3926
Echinococcus multilocularis 0.0206 0.2381 0.2381
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0853 0.2839
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4169 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0206 0.2381 0.5415
Echinococcus granulosus tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Brugia malayi Tyrosine-protein kinase PR2 0.0144 0.1637 0.3794
Loa Loa (eye worm) RGC/RGC protein kinase 0.0144 0.1637 0.3723
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Trypanosoma brucei Flagellum attachment zone protein 20 0.0144 0.1637 0.5451
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Plasmodium vivax tyrosine kinase-like protein, putative 0.0144 0.1637 1
Echinococcus granulosus receptor type guanylyl cyclase 0.0144 0.1637 0.1637
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.0853 0.2839
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0144 0.1637 0.1637
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.4169 1
Echinococcus granulosus tyrosine protein kinase csk 0.0144 0.1637 0.1637
Loa Loa (eye worm) TK/DDR protein kinase 0.0144 0.1637 0.3723
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0318 0.1057
Trypanosoma brucei Pseudokinase, putative 0.0144 0.1637 0.5451
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Schistosoma mansoni cpg binding protein 0.0037 0.033 0.033
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0144 0.1637 0.3723
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0228 0.1393
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0228 0.1153
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.3003 1
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0445 0.0445
Echinococcus multilocularis signal transduction protein lnk realted 0.0206 0.2381 0.2381
Loa Loa (eye worm) RGC/RGC protein kinase 0.0144 0.1637 0.3723
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Entamoeba histolytica tyrosin kinase, putative 0.0144 0.1637 0.3926
Echinococcus granulosus raf serine:threonine protein kinase 0.0144 0.1637 0.1637
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0556 0.0556
Echinococcus multilocularis tyrosine protein kinase Fyn 0.035 0.4133 0.4133
Onchocerca volvulus 0.0144 0.1637 0.3794
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0144 0.1637 0.1637
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0144 0.1637 0.1637
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0228 0.1393
Schistosoma mansoni ephrin receptor 0.0144 0.1637 0.1637
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Echinococcus granulosus insulin receptor 0.0144 0.1637 0.1637
Loa Loa (eye worm) STAT protein 0.0206 0.2381 0.5415
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0318 0.1057
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.1637 0.3926
Trichomonas vaginalis protein tyrosine kinase, putative 0.0144 0.1637 0.3926
Trichomonas vaginalis Citrate lyase beta chain, putative 0.003 0.0244 0.0586
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0144 0.1637 0.1637
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.0853 0.1939
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0228 0.0748
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0318 0.1605
Echinococcus multilocularis N chimaerin 0.0206 0.2381 0.2381
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.1637 0.3926
Echinococcus granulosus SH2 motif 0.0206 0.2381 0.2381
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4169 1
Brugia malayi Tensin 0.0206 0.2381 0.5518
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Onchocerca volvulus 0.0144 0.1637 0.3794
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0683 0.4171
Brugia malayi hypothetical protein 0.0144 0.1637 0.3794
Leishmania major GTP-binding protein, putative 0.0026 0.0196 0.0654
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0144 0.1637 0.3926
Echinococcus multilocularis tyrosine kinase 0.035 0.4133 0.4133
Echinococcus granulosus epidermal growth factor receptor 0.0144 0.1637 0.1637
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0144 0.1637 0.1637
Entamoeba histolytica tyrosin kinase, putative 0.0144 0.1637 0.3926
Schistosoma mansoni tensin 0.0206 0.2381 0.2381
Echinococcus multilocularis kinase suppressor of Ras 1 0.0144 0.1637 0.1637
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4169 1
Trypanosoma brucei hypothetical protein, conserved 0.0257 0.3003 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0144 0.1637 0.5451
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Entamoeba histolytica serine/threonine kinase, putative 0.0144 0.1637 0.3926
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0144 0.1637 0.1637
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0308 0.1881
Brugia malayi Furin-like cysteine rich region family protein 0.0144 0.1637 0.3794
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0028 0.0228 0.718
Brugia malayi SH2 domain containing protein 0.0206 0.2381 0.5518
Brugia malayi SH2 domain containing protein 0.035 0.4133 0.9578
Echinococcus multilocularis heat shock protein 70 0.0144 0.1637 0.1637
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0144 0.1637 0.1637
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0556 0.0556
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0028 0.0228 0.0547
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.1978 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0556 0.0556
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0196 0.0471
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.003 0.0244 0.1235
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0144 0.1637 0.1637
Brugia malayi tRNA modification GTPase TrmE family protein 0.0206 0.2381 0.5518
Echinococcus granulosus tensin 0.0206 0.2381 0.2381
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Echinococcus granulosus protein tyrosine kinase 0.0144 0.1637 0.1637
Trypanosoma cruzi protein kinase, putative 0.0144 0.1637 0.5451
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0144 0.1637 0.3723
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0015 0.0015
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0196 0.0455
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0144 0.1637 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0261 0.3049 1
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0318 0.1605
Schistosoma mansoni tensin 0.0206 0.2381 0.2381
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0318 0.1057
Loa Loa (eye worm) TK/FAK protein kinase 0.0144 0.1637 0.3723
Leishmania major protein kinase, putative 0.0144 0.1637 0.5451
Trichomonas vaginalis AGC family protein kinase 0.0144 0.1637 0.3926
Schistosoma mansoni tyrosine kinase 0.035 0.4133 0.4133
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.1637 0.1637
Plasmodium vivax importin-beta 2, putative 0.0035 0.0308 0.1881
Schistosoma mansoni protein kinase 0.0144 0.1637 0.1637
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0203 0.047
Echinococcus multilocularis epidermal growth factor receptor 0.0144 0.1637 0.1637
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0228 0.1393
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0144 0.1637 0.3926
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0228 0.0759
Echinococcus multilocularis protein KINase family member (kin 25) 0.0144 0.1637 0.1637
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0015 0.0015
Brugia malayi Sex muscle abnormal protein 5 0.0206 0.2381 0.5518
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) TK protein kinase 0.0144 0.1637 0.3723
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Loa Loa (eye worm) hypothetical protein 0.035 0.4133 0.9399
Schistosoma mansoni cpg binding protein 0.0035 0.0306 0.0306
Echinococcus multilocularis tyrosine protein kinase shark 0.035 0.4133 0.4133
Echinococcus multilocularis tyrosine protein kinase Fyn 0.035 0.4133 0.4133
Schistosoma mansoni shc transforming protein 0.0206 0.2381 0.2381
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0318 0.0318
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0556 0.1264
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Brugia malayi SH2 domain containing protein 0.0206 0.2381 0.5518
Trichomonas vaginalis conserved hypothetical protein 0.0144 0.1637 0.3926
Entamoeba histolytica hypothetical protein, conserved 0.0144 0.1637 0.3926
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0318 0.0318
Schistosoma mansoni ephrin receptor 0.0144 0.1637 0.1637
Onchocerca volvulus 0.0144 0.1637 0.3794
Echinococcus granulosus SH2 domain containing adapter protein F 0.0206 0.2381 0.2381
Echinococcus granulosus N chimaerin 0.0206 0.2381 0.2381
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Echinococcus multilocularis snurportin 1 0.0372 0.4397 0.4397
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Entamoeba histolytica SH2-protein kinase domain containing protein 0.035 0.4133 0.9913
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0318 0.194
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0206 0.2381 0.5415
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0144 0.1637 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0144 0.1637 0.3794
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0103 0.1133 0.3716
Brugia malayi Tyrosine-protein kinase abl-1 0.035 0.4133 0.9578
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) SH2 domain-containing protein 0.0206 0.2381 0.5415
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0228 0.0759
Trypanosoma cruzi protein kinase, putative 0.0144 0.1637 0.5451
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Schistosoma mansoni tyrosine kinase 0.0144 0.1637 0.1637
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0144 0.1637 0.1637
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0206 0.2381 0.5518
Schistosoma mansoni tyrosine kinase 0.035 0.4133 0.4133
Schistosoma mansoni signal transduction protein lnk-related 0.0206 0.2381 0.2381
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.5881 0.5881
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0775 0.0775
Entamoeba histolytica serine/threonine kinase, putative 0.0144 0.1637 0.3926
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0144 0.1637 0.3723
Plasmodium falciparum thioredoxin reductase 0.0103 0.1133 0.692
Entamoeba histolytica protein kinase, putative 0.0144 0.1637 0.3926
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0144 0.1637 0.3794
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1637 0.3926
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0144 0.1637 0.5451
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Plasmodium falciparum protein kinase, putative 0.0144 0.1637 1
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Echinococcus granulosus kinase suppressor of Ras 1 0.0144 0.1637 0.1637
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.1637 0.3794
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0144 0.1637 0.1637
Loa Loa (eye worm) TK/FER protein kinase 0.035 0.4133 0.9399
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Plasmodium falciparum tyrosine kinase-like protein 0.0144 0.1637 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0144 0.1637 0.3723
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Echinococcus granulosus tyrosine protein kinase Src42A 0.0206 0.2381 0.2381
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.1637 0.3794
Loa Loa (eye worm) TK/CSK protein kinase 0.0144 0.1637 0.3723
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.3003 1
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Brugia malayi hypothetical protein 0.0206 0.2381 0.5518
Echinococcus granulosus tyrosine protein kinase shark 0.035 0.4133 0.4133
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0196 0.0196
Brugia malayi Protein kinase domain containing protein 0.035 0.4133 0.9578
Onchocerca volvulus 0.0035 0.0306 0.071
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.003 0.0244 0.0801
Echinococcus granulosus fibroblast growth factor receptor 4 0.0144 0.1637 0.1637
Echinococcus multilocularis NCK adaptor protein 0.0206 0.2381 0.2381
Brugia malayi Importin beta-1 subunit 0.0035 0.0308 0.0714
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0318 0.1057
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0206 0.2381 0.2381
Echinococcus multilocularis FL cytokine receptor 0.0144 0.1637 0.1637
Echinococcus multilocularis raf serine:threonine protein kinase 0.0144 0.1637 0.1637
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0206 0.2381 0.2381
Giardia lamblia Kinase 0.0144 0.1637 0.3926
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Brugia malayi hypothetical protein 0.0144 0.1637 0.3794
Mycobacterium ulcerans hypothetical protein 0.003 0.0244 0.1235
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.0853 0.0853
Trypanosoma brucei trypanothione reductase 0.0103 0.1133 0.3772
Echinococcus granulosus activated cdc42 kinase 1 0.0144 0.1637 0.1637
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0144 0.1637 1
Echinococcus granulosus suppressor of cytokine signaling 7 0.0206 0.2381 0.2381
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Treponema pallidum NADH oxidase 0.0036 0.0318 0.0762
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0318 1
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0244 0.0814
Echinococcus multilocularis SH2 motif 0.0206 0.2381 0.2381
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0206 0.2381 0.5711
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0308 0.1025
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0234 0.2731 0.8958
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Brugia malayi Protein kinase domain containing protein 0.0144 0.1637 0.3794
Brugia malayi Variant SH3 domain containing protein 0.0206 0.2381 0.5518
Brugia malayi Protein kinase domain containing protein 0.035 0.4133 0.9578
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0228 0.0759
Trichomonas vaginalis ran, putative 0.0026 0.0196 0.0471
Onchocerca volvulus 0.0144 0.1637 0.3794
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0144 0.1637 0.3926
Echinococcus granulosus thioredoxin glutathione reductase 0.0103 0.114 0.114
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0206 0.2381 0.2381
Entamoeba histolytica Ran family GTPase 0.0026 0.0196 0.0471
Echinococcus granulosus tyrosine protein kinase ABL1 0.035 0.4133 0.4133
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Entamoeba histolytica tyrosine kinase, putative 0.0144 0.1637 0.3926
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Trichomonas vaginalis TKL family protein kinase 0.0144 0.1637 0.3926
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0196 0.1199
Entamoeba histolytica serine/threonine kinase, putative 0.0144 0.1637 0.3926
Loa Loa (eye worm) TK/ACK protein kinase 0.0144 0.1637 0.3723
Loa Loa (eye worm) hypothetical protein 0.0206 0.2381 0.5415
Loa Loa (eye worm) hypothetical protein 0.0144 0.1637 0.3723
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0318 0.1057
Entamoeba histolytica hypothetical protein 0.0144 0.1637 0.3926
Brugia malayi ephrin receptor 1 precursor 0.0144 0.1637 0.3794
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0228 0.1153

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 53 uM PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.5849 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 1.6511 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 9.2 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 17.7407 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 19.9526 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485342, AID485388] ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 56.2341 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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