Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0133 | 0.0485 | 0.0585 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0395 | 0.1537 | 0.2889 |
Trypanosoma brucei | Trans-2-enoyl-ACP reductase 2, putative | 0.0082 | 0.0279 | 0.2014 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.132 | 0.5252 | 0.5249 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.1402 | 0.5581 | 0.7059 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0026 | 0.0094 |
Mycobacterium ulcerans | acyl carrier protein | 0.0133 | 0.0485 | 0.0585 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.132 | 0.5252 | 0.6636 |
Leishmania major | oxidoreductase-like protein | 0.0082 | 0.0279 | 0.1725 |
Schistosoma mansoni | lamin | 0.0026 | 0.0054 | 0.0259 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.0014 | 0.0027 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0085 | 0.0463 |
Toxoplasma gondii | Zn-containing alcohol dehydrogenase | 0.0082 | 0.0279 | 0.0475 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.1973 | 0.7875 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0398 | 0.1547 | 1 |
Toxoplasma gondii | acyl carrier protein ACP | 0.0133 | 0.0485 | 0.0845 |
Mycobacterium tuberculosis | Probable alcohol dehydrogenase Adh | 0.0082 | 0.0279 | 0.0258 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0856 | 0.3389 | 0.6062 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase | 0.0082 | 0.0279 | 0.0322 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0042 | 0.0118 | 0.0051 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.1402 | 0.5581 | 0.7059 |
Schistosoma mansoni | zinc binding dehydrogenase | 0.0082 | 0.0279 | 0.1725 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0042 | 0.0118 | 0.0051 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0085 | 0.0127 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0026 | 0.002 |
Schistosoma mansoni | polycystin 1-related | 0.0019 | 0.0026 | 0.0075 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0026 | 0.0048 |
Onchocerca volvulus | 0.0264 | 0.1011 | 0.105 | |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0763 | 0.0861 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0331 | 0.128 | 0.2386 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0042 | 0.0118 | 0.0051 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.0485 | 0.3071 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0133 | 0.0485 | 0.0585 |
Brugia malayi | Doublecortin family protein | 0.0019 | 0.0026 | 0.002 |
Mycobacterium tuberculosis | Probable NADP-dependent alcohol dehydrogenase AdhC | 0.0082 | 0.0279 | 0.0258 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0331 | 0.128 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0042 | 0.0118 | 0.0051 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.0197 | 0.1442 |
Mycobacterium leprae | Probable lipase LipE | 0.0042 | 0.0118 | 0.0051 |
Onchocerca volvulus | 0.1233 | 0.4904 | 0.515 | |
Loa Loa (eye worm) | phosphopantetheine attachment site family protein | 0.0133 | 0.0485 | 0.0548 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.128 | 0.5089 | 0.6428 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0082 | 0.0279 | 0.1725 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0202 | 0.0763 | 0.0879 |
Schistosoma mansoni | lamin | 0.0026 | 0.0054 | 0.0259 |
Mycobacterium leprae | Probable alcohol dehydrogenase AdhA | 0.0082 | 0.0279 | 0.0258 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0042 | 0.0118 | 0.0219 |
Schistosoma mansoni | lipoxygenase | 0.0053 | 0.0164 | 0.0974 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.132 | 0.5252 | 0.6636 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0133 | 0.0485 | 0.0522 |
Plasmodium vivax | acyl carrier protein, putative | 0.0133 | 0.0485 | 0.3717 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0133 | 0.0485 | 0.0522 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0197 | 0.1442 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0073 | 0.0244 | 0.0412 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0331 | 0.128 | 0.1446 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0415 | 0.1615 | 0.1972 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0331 | 0.128 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0284 | 0.0321 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Treponema pallidum | acyl carrier protein | 0.0133 | 0.0485 | 0.5 |
Mycobacterium ulcerans | malonyl CoA-acyl carrier protein transacylase FabD | 0.0083 | 0.0284 | 0.0329 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0085 | 0.0161 |
Mycobacterium ulcerans | oxidoreductase | 0.0082 | 0.0279 | 0.0322 |
Trypanosoma brucei | acyl transferase-like protein | 0.0083 | 0.0284 | 0.2056 |
Leishmania major | hypothetical protein, conserved | 0.0398 | 0.1547 | 1 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0036 | 0.0093 | 0.0512 |
Plasmodium vivax | malonyl CoA-acyl carrier protein transacylase precursor, putative | 0.0083 | 0.0284 | 0.2131 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0118 | 0.0051 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0133 | 0.0485 | 0.0522 |
Brugia malayi | ADP-specific Phosphofructokinase/Glucokinase conserved region family protein | 0.0083 | 0.0284 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.2218 | 0.8857 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0019 | 0.0026 | 0.0091 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0078 | 0.0145 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0026 | 0.0021 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0323 | 0.1245 | 0.1497 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.0026 | 0.003 |
Plasmodium falciparum | malonyl CoA-acyl carrier protein transacylase | 0.0083 | 0.0284 | 0.2131 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.0014 | 0.0016 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.132 | 0.5252 | 0.6658 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase AdhC | 0.0082 | 0.0279 | 0.0322 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0085 | 0.0096 |
Mycobacterium tuberculosis | Possible oxidoreductase FadB5 | 0.0082 | 0.0279 | 0.0258 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0042 | 0.0118 | 0.0116 |
Leishmania major | d-xylulose reductase, putative | 0.0082 | 0.0279 | 0.1725 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.0244 | 0.0277 |
Brugia malayi | AMP-binding enzyme family protein | 0.1233 | 0.4904 | 0.4901 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0014 | 0.0016 |
Echinococcus multilocularis | Malonyl coenzyme A acyl carrier protein transacylase | 0.0083 | 0.0284 | 0.0534 |
Mycobacterium leprae | PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 | 0.0202 | 0.0763 | 0.0879 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0026 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0026 | 0.0029 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0083 | 0.0284 | 0.176 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0048 | 0.0144 | 0.1024 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0763 | 0.0861 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0026 | 0.003 |
Mycobacterium tuberculosis | Probable alcohol dehydrogenase AdhA | 0.0082 | 0.0279 | 0.0258 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0166 | 0.0271 |
Brugia malayi | AMP-binding enzyme family protein | 0.0406 | 0.158 | 0.1575 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.0093 | 0.0175 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0085 | 0.056 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0398 | 0.1547 | 0.1542 |
Echinococcus granulosus | AMP dependent ligase | 0.0133 | 0.0485 | 0.0904 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0026 | 0.0021 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0054 | 0.0101 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0014 | 0.0027 |
Onchocerca volvulus | 0.0034 | 0.0085 | 0.0075 | |
Onchocerca volvulus | 0.0054 | 0.0165 | 0.0159 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0082 | 0.0279 | 0.0258 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.132 | 0.5252 | 0.6658 |
Leishmania major | acyl carrier protein, putative | 0.0133 | 0.0485 | 0.3071 |
Brugia malayi | Pre-SET motif family protein | 0.0232 | 0.0882 | 0.0877 |
Loa Loa (eye worm) | fatty acid synthase | 0.1303 | 0.5181 | 0.585 |
Chlamydia trachomatis | acyl carrier protein | 0.0133 | 0.0485 | 0.2016 |
Onchocerca volvulus | 0.0019 | 0.0026 | 0.0012 | |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0014 | 0.0027 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0118 | 0.0673 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0082 | 0.0279 | 0.0273 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase | 0.0082 | 0.0279 | 0.5618 |
Loa Loa (eye worm) | acyl carrier protein | 0.0133 | 0.0485 | 0.0548 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0056 | 0.0176 | 0.1273 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0082 | 0.0279 | 0.2088 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0026 | 0.0075 |
Mycobacterium ulcerans | lipase LipD | 0.0042 | 0.0118 | 0.0116 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0232 | 0.0882 | 0.0996 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0082 | 0.0279 | 0.0322 |
Schistosoma mansoni | acyl carrier protein | 0.0133 | 0.0485 | 0.3071 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0019 | 0.0026 | 0.0049 |
Echinococcus multilocularis | conserved hypothetical protein | 0.1337 | 0.532 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0118 | 0.0051 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0082 | 0.0279 | 0.2088 |
Brugia malayi | Alcohol dehydrogenase class III | 0.0082 | 0.0279 | 0.0273 |
Onchocerca volvulus | 0.0042 | 0.0118 | 0.0109 | |
Mycobacterium ulcerans | zinc-type alcohol dehydrogenase AdhD | 0.0082 | 0.0279 | 0.0322 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.238 | 0.9508 | 1 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks3 | 0.0202 | 0.0763 | 0.0879 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0082 | 0.0279 | 0.2088 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0093 | 0.0085 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0061 | 0.0069 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.132 | 0.5252 | 0.6658 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0006 | 0.0006 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.1973 | 0.7875 | 1 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0019 | 0.0026 | 0.0048 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0034 | 0.0085 | 0.0161 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0073 | 0.0244 | 0.1498 |
Loa Loa (eye worm) | hypothetical protein | 0.074 | 0.292 | 0.3297 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0014 | 0.0027 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0873 | 0.3456 | 0.4333 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase | 0.0133 | 0.0485 | 0.0585 |
Echinococcus granulosus | NADH dehydrogenase | 0.0133 | 0.0485 | 0.0904 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0118 | 0.0112 |
Loa Loa (eye worm) | alcohol dehydrogenase class III | 0.0082 | 0.0279 | 0.0315 |
Wolbachia endosymbiont of Brugia malayi | ACP S-malonyltransferase | 0.0083 | 0.0284 | 0.1611 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.1402 | 0.5581 | 0.7059 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0263 | 0.1007 | 0.1892 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0014 | 0.0009 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0133 | 0.0485 | 0.0522 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0093 | 0.0511 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0133 | 0.0485 | 0.0585 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0082 | 0.0279 | 0.0273 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0093 | 0.0105 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0054 | 0.0061 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0331 | 0.128 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.0026 | 0.0077 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0197 | 0.1191 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0085 | 0.0463 |
Mycobacterium tuberculosis | Acyl carrier protein (ACP) MbtL | 0.0133 | 0.0485 | 0.0522 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0082 | 0.0279 | 0.0322 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0073 | 0.0244 | 0.0213 |
Mycobacterium ulcerans | polyketide synthase | 0.132 | 0.5252 | 0.6658 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0093 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0118 | 0.0133 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0133 | 0.0485 | 0.0585 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) | 0.0082 | 0.0279 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0118 | 0.0133 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0948 | 0.3759 | 0.4721 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0189 | 0.071 | 0.549 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0279 | 0.0315 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0014 | 0.0009 |
Mycobacterium ulcerans | Zn-dependent alcohol dehydrogenase, AdhX | 0.0082 | 0.0279 | 0.0322 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0812 | 0.3209 | 0.6033 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0093 | 0.0511 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0067 | 0.0125 |
Trypanosoma brucei | Acyl carrier protein, mitochondrial | 0.0133 | 0.0485 | 0.3658 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0331 | 0.128 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0118 | 0.0133 |
Mycobacterium leprae | Probable S-nitrosomycothiol reductase MscR | 0.0082 | 0.0279 | 0.0258 |
Mycobacterium ulcerans | oxidoreductase | 0.0082 | 0.0279 | 0.0322 |
Echinococcus granulosus | dnaJ subfamily B | 0.0395 | 0.1537 | 0.2864 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.1402 | 0.5581 | 0.7059 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0454 | 0.1772 | 0.2173 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0085 | 0.0463 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0082 | 0.0279 | 0.1725 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0054 | 0.0049 |
Trichomonas vaginalis | set domain proteins, putative | 0.0264 | 0.1011 | 0.6503 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0073 | 0.0244 | 0.0455 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.1062 | 0.4216 | 0.5308 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0093 | 0.0141 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0406 | 0.158 | 0.1926 |
Mycobacterium tuberculosis | Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) | 0.0082 | 0.0279 | 0.0258 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0331 | 0.128 | 1 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.0082 | 0.0279 | 0.5618 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.1973 | 0.7875 | 1 |
Schistosoma mansoni | alcohol dehydrogenase | 0.0082 | 0.0279 | 0.1725 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0331 | 0.128 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0093 | 0.053 |
Mycobacterium ulcerans | beta-lactamase | 0.0042 | 0.0118 | 0.0116 |
Echinococcus granulosus | lamin | 0.0026 | 0.0054 | 0.0101 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0054 | 0.0061 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Onchocerca volvulus | 0.0028 | 0.0061 | 0.0049 | |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0014 | 0.0009 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0042 | 0.0118 | 0.0051 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0873 | 0.3456 | 0.437 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0042 | 0.0118 | 0.0221 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0036 | 0.0093 | 0.0175 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0085 | 0.008 |
Mycobacterium leprae | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0133 | 0.0485 | 0.0522 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.132 | 0.5252 | 0.6636 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0026 | 0.0029 |
Mycobacterium tuberculosis | Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) | 0.0082 | 0.0279 | 0.0258 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0036 | 0.0093 | 0.0087 |
Echinococcus granulosus | acyl carrier protein mitochondrial | 0.0133 | 0.0485 | 0.0904 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0331 | 0.128 | 0.8261 |
Leishmania major | hypothetical protein, conserved | 0.0083 | 0.0284 | 0.176 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0042 | 0.0118 | 0.0051 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.0415 | 0.1615 | 0.1972 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0014 | 0.0027 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0026 | 0.002 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0083 | 0.0284 | 0.176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0133 | 0.0485 | 0.0522 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0093 | 0.0511 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0014 | 0.0027 |
Mycobacterium tuberculosis | S-nitrosomycothiol reductase MscR | 0.0082 | 0.0279 | 0.0258 |
Schistosoma mansoni | survival motor neuron protein | 0.0054 | 0.0165 | 0.0983 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0267 | 0.1023 | 0.1213 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.1233 | 0.4904 | 0.619 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0082 | 0.0279 | 0.0273 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0054 | 0.0102 |
Echinococcus multilocularis | AMP dependent ligase | 0.0133 | 0.0485 | 0.0912 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0082 | 0.0279 | 0.2088 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.11 | 0.4368 | 0.5503 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0093 | 0.0511 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0026 | 0.0075 |
Mycobacterium ulcerans | NADP-dependent oxidoreductase | 0.0082 | 0.0279 | 0.0322 |
Leishmania major | zinc binding dehydrogenase-like protein | 0.0082 | 0.0279 | 0.1725 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0133 | 0.0485 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0052 | 0.0059 |
Loa Loa (eye worm) | beta-lactamase | 0.0042 | 0.0118 | 0.0133 |
Loa Loa (eye worm) | TK/FAK protein kinase | 0.0247 | 0.0942 | 0.1063 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0331 | 0.128 | 1 |
Mycobacterium leprae | Probable oxidireductase | 0.0082 | 0.0279 | 0.0258 |
Echinococcus multilocularis | protein tyrosine kinase | 0.0244 | 0.093 | 0.1749 |
Mycobacterium ulcerans | hypothetical protein | 0.0042 | 0.0118 | 0.0116 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0093 | 0.0619 |
Echinococcus multilocularis | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0082 | 0.0279 | 0.0524 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.132 | 0.5252 | 0.6658 |
Echinococcus granulosus | RUN | 0.0019 | 0.0026 | 0.0048 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.0082 | 0.0279 | 0.2088 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0331 | 0.128 | 0.1598 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0036 | 0.0093 | 0.0512 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0067 | 0.0345 |
Mycobacterium ulcerans | NADPH quinone oxidoreductase FadB4 | 0.0082 | 0.0279 | 0.0322 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.075 | 0.2964 | 0.3702 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0118 | 0.0133 |
Mycobacterium tuberculosis | Meromycolate extension acyl carrier protein AcpM | 0.0133 | 0.0485 | 0.0522 |
Onchocerca volvulus | 0.0042 | 0.0118 | 0.0109 | |
Echinococcus granulosus | Malonyl coenzyme A acyl carrier protein transacylase | 0.0083 | 0.0284 | 0.053 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.0014 | 0.0016 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0082 | 0.0279 | 0.2088 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0073 | 0.0244 | 0.0459 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0118 | 0.0673 |
Mycobacterium tuberculosis | Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) | 0.0082 | 0.0279 | 0.0258 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.128 | 0.5089 | 0.6428 |
Onchocerca volvulus | Putative alcohol dehydrogenase | 0.0082 | 0.0279 | 0.0278 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0036 | 0.0093 | 0.0173 |
Onchocerca volvulus | 0.0082 | 0.0279 | 0.0278 | |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0042 | 0.0118 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0118 | 0.0133 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0093 | 0.062 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase Adh | 0.0082 | 0.0279 | 0.0322 |
Onchocerca volvulus | 0.0019 | 0.0026 | 0.0012 | |
Echinococcus granulosus | hypothetical protein | 0.1348 | 0.5366 | 1 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.1973 | 0.7875 | 1 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.108 | 0.4286 | 0.5397 |
Onchocerca volvulus | 0.0082 | 0.0279 | 0.0278 | |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0133 | 0.0485 | 0.0585 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.1402 | 0.5581 | 1 |
Mycobacterium ulcerans | oxidoreductase FadB5 | 0.0082 | 0.0279 | 0.0322 |
Loa Loa (eye worm) | doublecortin family protein | 0.0019 | 0.0026 | 0.0029 |
Trypanosoma cruzi | Acyl carrier protein, mitochondrial, putative | 0.0133 | 0.0485 | 0.3717 |
Mycobacterium ulcerans | hypothetical protein | 0.0133 | 0.0485 | 0.0585 |
Brugia malayi | Serotonin receptor | 0.0458 | 0.1791 | 0.1786 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0073 | 0.0244 | 0.1498 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0197 | 0.1191 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.1402 | 0.5581 | 0.7078 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0083 | 0.0284 | 0.176 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0197 | 0.1442 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0067 | 0.0127 |
Mycobacterium ulcerans | thioesterase | 0.11 | 0.4368 | 0.5532 |
Echinococcus multilocularis | Acyl carrier protein, mitochondrial | 0.0133 | 0.0485 | 0.0912 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0082 | 0.0279 | 0.2088 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0054 | 0.0165 | 0.016 |
Mycobacterium tuberculosis | Conserved protein | 0.0398 | 0.1547 | 0.1884 |
Schistosoma mansoni | tyrosine kinase | 0.0244 | 0.093 | 0.5976 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0667 | 0.2629 | 0.4697 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0054 | 0.0102 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0036 | 0.0093 | 0.1669 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0263 | 0.1007 | 0.1876 |
Trypanosoma brucei | oxidoreductase, putative | 0.0082 | 0.0279 | 0.2014 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0118 | 0.0133 |
Schistosoma mansoni | methyltransferase-related | 0.0398 | 0.1547 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0118 | 0.0814 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0331 | 0.128 | 0.1598 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0053 | 0.0164 | 0.0308 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0118 | 0.0673 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0093 | 0.0512 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0014 | 0.0009 |
Echinococcus granulosus | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0082 | 0.0279 | 0.052 |
Toxoplasma gondii | type I fatty acid synthase | 0.0202 | 0.0763 | 0.1344 |
Mycobacterium leprae | conserved hypothetical protein | 0.0133 | 0.0485 | 0.0522 |
Leishmania major | hypothetical protein, conserved | 0.0042 | 0.0118 | 0.0673 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0093 | 0.1665 |
Trypanosoma brucei | oxidoreductase, putative | 0.0082 | 0.0279 | 0.2014 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0093 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0279 | 0.0315 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0415 | 0.1615 | 0.2024 |
Plasmodium falciparum | acyl carrier protein | 0.0133 | 0.0485 | 0.3717 |
Wolbachia endosymbiont of Brugia malayi | NADPH:quinone reductase | 0.0082 | 0.0279 | 0.1566 |
Onchocerca volvulus | 0.0133 | 0.0485 | 0.0496 | |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0026 | 0.0075 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0093 | 0.062 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0014 | 0.0009 |
Leishmania major | oxidoreductase, putative | 0.0082 | 0.0279 | 0.1725 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0042 | 0.0118 | 0.0727 |
Brugia malayi | Phosphopantetheine attachment site family protein | 0.0133 | 0.0485 | 0.048 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.11 | 0.4368 | 0.5503 |
Trypanosoma cruzi | acyl transferase-like protein | 0.0083 | 0.0284 | 0.2131 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0014 | 0.0027 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0118 | 0.0051 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.0244 | 0.0277 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0042 | 0.0118 | 0.0112 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0054 | 0.0101 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks4 | 0.0202 | 0.0763 | 0.0879 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0093 | 0.0619 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0873 | 0.3456 | 0.437 |
Toxoplasma gondii | quinone oxidoreductase, putative | 0.0082 | 0.0279 | 0.0475 |
Plasmodium vivax | hypothetical protein, conserved | 0.0189 | 0.071 | 0.549 |
Mycobacterium tuberculosis | Possible dehydrogenase | 0.0082 | 0.0279 | 0.0258 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0.0118 | 0.0814 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0093 | 0.0532 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.1233 | 0.4904 | 0.5536 |
Mycobacterium tuberculosis | Probable acyl carrier protein AcpA (ACP) | 0.0133 | 0.0485 | 0.0522 |
Brugia malayi | beta-lactamase | 0.0042 | 0.0118 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0054 | 0.0061 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0026 | 0.0048 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.0093 | 0.0173 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0014 | 0.0009 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0014 | 0.0009 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0093 | 0.0174 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0085 | 0.0463 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0279 | 0.0315 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0331 | 0.128 | 0.2407 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.0014 | 0.0016 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0534 | 0.2094 | 0.2586 |
Onchocerca volvulus | 0.2298 | 0.9179 | 0.9653 | |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0279 | 0.0315 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0061 | 0.0055 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.094 | 0.3724 | 0.6664 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0406 | 0.158 | 0.1979 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0093 | 0.0511 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.0082 | 0.0279 | 0.0322 |
Mycobacterium ulcerans | quinone reductase Qor | 0.0082 | 0.0279 | 0.0322 |
Mycobacterium ulcerans | acyl carrier protein | 0.0133 | 0.0485 | 0.0585 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0042 | 0.0118 | 0.0133 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0118 | 0.0673 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0331 | 0.128 | 0.1598 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0082 | 0.0279 | 0.2088 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.1402 | 0.5581 | 0.7078 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0036 | 0.0093 | 0.0512 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0118 | 0.0673 |
Leishmania major | quinone oxidoreductase, putative | 0.0082 | 0.0279 | 0.1725 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.132 | 0.5252 | 0.6636 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.0085 | 0.0159 |
Trichomonas vaginalis | esterase, putative | 0.0042 | 0.0118 | 0.0673 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.0093 | 0.0173 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0082 | 0.0279 | 0.1725 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0118 | 0.0112 |
Wolbachia endosymbiont of Brugia malayi | acyl carrier protein | 0.0133 | 0.0485 | 0.3303 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0073 | 0.0244 | 0.1498 |
Mycobacterium tuberculosis | Possible dehydrogenase | 0.0082 | 0.0279 | 0.0258 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0061 | 0.0303 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0118 | 0.0673 |
Leishmania major | zinc-binding dehydrogenase-like protein | 0.0082 | 0.0279 | 0.1725 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0067 | 0.0345 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase AdhE2 | 0.0082 | 0.0279 | 0.0322 |
Mycobacterium ulcerans | polyketide synthase | 0.1402 | 0.5581 | 0.7078 |
Echinococcus multilocularis | NADH dehydrogenase | 0.0133 | 0.0485 | 0.0912 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0054 | 0.0049 |
Echinococcus multilocularis | RUN | 0.0019 | 0.0026 | 0.0049 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.132 | 0.5252 | 0.6636 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.0014 | 0.0016 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0191 | 0.1151 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0133 | 0.0485 | 0.0522 |
Echinococcus granulosus | protein tyrosine kinase | 0.0244 | 0.093 | 0.1734 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0054 | 0.0102 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0165 | 0.0983 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0053 | 0.0164 | 0.0305 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.0014 | 0.0016 |
Mycobacterium ulcerans | thioesterase TesA | 0.11 | 0.4368 | 0.5532 |
Giardia lamblia | Methyltransferase like 2 | 0.0398 | 0.1547 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0118 | 0.0814 |
Mycobacterium leprae | PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC | 0.0082 | 0.0279 | 0.0258 |
Leishmania major | nuclear receptor binding factor-like protein | 0.0082 | 0.0279 | 0.1725 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0093 | 0.0173 |
Brugia malayi | hypothetical protein | 0.0263 | 0.1007 | 0.1002 |
Schistosoma mansoni | hypothetical protein | 0.0395 | 0.1537 | 0.9934 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.1062 | 0.4216 | 0.5338 |
Leishmania major | NADP-dependent alcohol dehydrogenase, putative | 0.0082 | 0.0279 | 0.1725 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0398 | 0.1547 | 0.1884 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0036 | 0.0093 | 0.0512 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.0093 | 0.0175 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.1402 | 0.5581 | 0.7059 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.1062 | 0.4216 | 0.5338 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0054 | 0.0259 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.0244 | 0.0277 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0197 | 0.1442 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.0082 | 0.0279 | 0.0322 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0042 | 0.0118 | 0.0051 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.0014 | 0.0027 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0026 | 0.0049 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0331 | 0.128 | 0.8261 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0118 | 0.0673 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.1402 | 0.5581 | 0.7059 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0133 | 0.0485 | 1 |
Brugia malayi | acyl carrier protein, mitochondrial precursor, putative | 0.0133 | 0.0485 | 0.048 |
Toxoplasma gondii | ABC1 family protein | 0.0042 | 0.0118 | 0.0185 |
Mycobacterium ulcerans | fatty-acid-CoA ligase FadD9 | 0.0133 | 0.0485 | 0.0585 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD-dependent AdhB | 0.0082 | 0.0279 | 0.0322 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Trypanosoma cruzi | acyl transferase-like protein, putative | 0.0083 | 0.0284 | 0.2131 |
Onchocerca volvulus | 0.0042 | 0.0118 | 0.0109 | |
Onchocerca volvulus | 0.0026 | 0.0054 | 0.0042 | |
Schistosoma mansoni | loxhd1 | 0.0019 | 0.0026 | 0.0075 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Onchocerca volvulus | Acyl carrier protein, mitochondrial homolog | 0.0133 | 0.0485 | 0.0496 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0042 | 0.0118 | 0.0116 |
Mycobacterium ulcerans | dehydrogenase | 0.0082 | 0.0279 | 0.0322 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.1007 | 0.1137 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0133 | 0.0485 | 0.0522 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.0082 | 0.0279 | 0.5618 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0036 | 0.0093 | 0.0512 |
Brugia malayi | Protein kinase domain containing protein | 0.0247 | 0.0942 | 0.0937 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0197 | 0.1191 |
Schistosoma mansoni | lipoxygenase | 0.0019 | 0.0026 | 0.0075 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0331 | 0.128 | 0.1276 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0093 | 0.0511 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0202 | 0.0763 | 0.0879 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.0082 | 0.0279 | 0.2088 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0026 | 0.0049 |
Onchocerca volvulus | 0.0026 | 0.0054 | 0.0042 | |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0133 | 0.0485 | 0.048 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0197 | 0.1361 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0331 | 0.128 | 0.2274 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0026 | 0.003 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0812 | 0.3209 | 0.5981 |
Loa Loa (eye worm) | acyl carrier protein | 0.0607 | 0.2388 | 0.2696 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0019 | 0.0026 | 0.0091 |
Toxoplasma gondii | acyl transferase domain-containing protein | 0.0083 | 0.0284 | 0.0485 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.0014 | 0.0027 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.328 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.285 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.236 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.155 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.116 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.