Detailed information for compound 1603880

Basic information

Technical information
  • TDR Targets ID: 1603880
  • Name: 2-(3,4-dichlorophenyl)-N-[3-[4-(3-piperidin-1 -ylpropyl)piperazin-1-yl]propyl]acetamide; ox alic acid
  • MW: 545.499 | Formula: C25H38Cl2N4O5
  • H donors: 3 H acceptors: 5 LogP: -0.97 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)C(=O)O.O=C(Cc1ccc(c(c1)Cl)Cl)NCCCN1CCN(CC1)CCCN1CCCCC1
  • InChi: 1S/C23H36Cl2N4O.C2H2O4/c24-21-7-6-20(18-22(21)25)19-23(30)26-8-4-11-28-14-16-29(17-15-28)13-5-12-27-9-2-1-3-10-27;3-1(4)2(5)6/h6-7,18H,1-5,8-17,19H2,(H,26,30);(H,3,4)(H,5,6)
  • InChiKey: MUWPBAAUIROHSF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(3,4-dichlorophenyl)-N-[3-[4-[3-(1-piperidyl)propyl]piperazin-1-yl]propyl]acetamide; oxalic acid
  • 2-(3,4-dichlorophenyl)-N-[3-[4-[3-(1-piperidyl)propyl]-1-piperazinyl]propyl]acetamide; oxalic acid
  • 2-(3,4-dichlorophenyl)-N-[3-[4-(3-piperidinopropyl)piperazin-1-yl]propyl]acetamide; oxalic acid
  • 2-(3,4-dichlorophenyl)-N-[3-[4-(3-piperidin-1-ylpropyl)piperazin-1-yl]propyl]ethanamide; ethanedioic acid
  • NSC708560

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0069 0.0299
Toxoplasma gondii type I fatty acid synthase, putative 0.0259 0.1499 0.6454
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0027 0.0026 0.0077
Loa Loa (eye worm) hypothetical protein 0.0091 0.043 0.1147
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0331 0.1956 0.4554
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0363 0.2164 0.6518
Schistosoma mansoni hypothetical protein 0.0056 0.021 0.021
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0089 0.0419 0.1198
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0217 0.1232 0.1232
Echinococcus multilocularis polycomb protein SCMH1 0.0055 0.0204 0.0204
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.02 0.1002
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0299 0.0299
Brugia malayi Pre-SET motif family protein 0.024 0.138 0.326
Mycobacterium ulcerans DNA polymerase IV 0.0092 0.0438 0.1325
Plasmodium vivax acyl carrier protein, putative 0.0037 0.0088 0.1544
Onchocerca volvulus 0.0096 0.0464 0.1037
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0092 0.0215
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0092 0.0343
Loa Loa (eye worm) 6-phosphofructokinase 0.0125 0.0651 0.1736
Echinococcus multilocularis histone acetyltransferase MYST2 0.0063 0.0252 0.0252
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0222 0.0591
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0063 0.0252 0.0252
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0055 0.0203 0.054
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0091 0.0434 0.0434
Mycobacterium ulcerans acyl carrier protein 0.0037 0.0088 0.0265
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0052 0.0185 0.3268
Echinococcus granulosus AMP dependent ligase 0.0039 0.0102 0.0102
Brugia malayi hypothetical protein 0.0274 0.1597 0.3774
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0069 0.1225
Chlamydia trachomatis pyruvate kinase 0.0038 0.0099 0.2275
Loa Loa (eye worm) hypothetical protein 0.0055 0.0204 0.0544
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.0386 0.1831
Loa Loa (eye worm) hypothetical protein 0.0041 0.0115 0.0306
Schistosoma mansoni hypothetical protein 0.0334 0.198 0.198
Echinococcus granulosus histone acetyltransferase MYST2 0.0063 0.0252 0.0252
Schistosoma mansoni heat shock protein 0.0037 0.0092 0.0092
Trichomonas vaginalis DNA polymerase eta, putative 0.0092 0.0438 0.2193
Leishmania major 4-coumarate:coa ligase-like protein 0.0055 0.0203 0.0472
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0026 0.006
Plasmodium vivax acyl-CoA synthetase, putative 0.0041 0.0115 0.2022
Loa Loa (eye worm) hypothetical protein 0.0041 0.0115 0.0306
Onchocerca volvulus 0.0218 0.124 0.2994
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0365 0.0973
Trypanosoma cruzi hypothetical protein, conserved 0.0245 0.1414 0.3292
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0114 0.058 0.1689
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.055 0.1281
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0037 0.0088 0.0207
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0092 0.0343
Leishmania major alpha glucosidase II subunit, putative 0.0084 0.0386 0.0898
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0698 0.4295 1
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0053 0.019 0.0501
Echinococcus multilocularis peregrin 0.0036 0.0085 0.0085
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0098 0.0479 0.1114
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0386 0.0898
Schistosoma mansoni mannose-6-phosphate isomerase 0.0112 0.0567 0.0567
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0114 0.058 0.1689
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0352 0.2094 0.6302
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.014 0.0223
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0056 0.0209 0.0557
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0651 0.3259
Brugia malayi Phosphopantetheine attachment site family protein 0.0037 0.0088 0.0207
Echinococcus granulosus heat shock protein 90 0.0037 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0204 0.1149 0.3063
Mycobacterium leprae Polyketide synthase Pks13 0.0543 0.3307 1
Echinococcus granulosus Protein patched homolog 1 0.0049 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0096 0.0464 0.1237
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0185 0.3268
Echinococcus multilocularis neutral alpha glucosidase AB 0.0084 0.0386 0.0386
Echinococcus multilocularis SAM and MBT domain containing protein 0.0055 0.0204 0.0204
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.024 0.1382 0.4133
Onchocerca volvulus Alhambra homolog 0.0034 0.0068 0.004
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.023 0.0953
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0073 0.0073
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0065 0.0065
Echinococcus multilocularis lysosomal alpha glucosidase 0.0377 0.225 0.225
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0438 0.102
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Loa Loa (eye worm) hypothetical protein 0.0049 0.0166 0.0442
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0098 0.0479 0.1114
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0356 0.2115 0.5641
Onchocerca volvulus Huntingtin homolog 0.0142 0.0757 0.1778
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0091 0.0434 0.7655
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0061 0.0243 0.0243
Plasmodium vivax heat shock protein 86, putative 0.0037 0.0092 0.163
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0261 0.1514 0.4535
Echinococcus granulosus mannose 6 phosphate isomerase 0.0112 0.0567 0.0567
Plasmodium falciparum acyl carrier protein 0.0037 0.0088 0.1544
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0096 0.0464 0.0464
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0055 0.0204 0.0204
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0292 0.1713 0.518
Schistosoma mansoni pyruvate kinase 0.0038 0.0099 0.0099
Trypanosoma brucei polo-like protein kinase 0.0109 0.055 0.1281
Plasmodium falciparum pyruvate kinase 0.0038 0.0099 0.1741
Brugia malayi Bromodomain containing protein 0.0086 0.0404 0.0954
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0438 0.102
Loa Loa (eye worm) hypothetical protein 0.0055 0.0203 0.0541
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0377 0.225 0.6
Leishmania major DNA polymerase eta, putative 0.0091 0.043 0.1001
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.014 0.0702
Schistosoma mansoni hypothetical protein 0.0047 0.0154 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.055 0.2753
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0028 0.0032 0.0074
Onchocerca volvulus Huntingtin homolog 0.0142 0.0757 0.1778
Trypanosoma cruzi pyruvate kinase 2, putative 0.0038 0.0099 0.023
Giardia lamblia PHD finger protein 15 0.0034 0.0068 0.0123
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.011 0.0554 0.0554
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0162 0.0376
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0363 0.2164 0.6518
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0092 0.0215
Echinococcus multilocularis Niemann Pick C1 protein 0.0163 0.0891 0.0891
Trichomonas vaginalis DNA helicase recq1, putative 0.0052 0.0187 0.0933
Plasmodium vivax SET domain protein, putative 0.0034 0.0073 0.1288
Schistosoma mansoni 6-phosphofructokinase 0.0125 0.0651 0.0651
Mycobacterium ulcerans thioesterase 0.0303 0.1779 0.538
Brugia malayi mbt repeat family protein 0.0055 0.0204 0.0482
Loa Loa (eye worm) hypothetical protein 0.0056 0.0209 0.0556
Onchocerca volvulus 0.0048 0.0157 0.0263
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0053 0.019 0.0574
Mycobacterium tuberculosis Conserved hypothetical protein 0.0368 0.2193 0.6605
Brugia malayi Endoplasmin precursor 0.0037 0.0092 0.0218
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0165 0.0901 0.2724
Brugia malayi 6-phosphofructokinase 0.0125 0.0651 0.1538
Trypanosoma brucei heat shock protein, putative 0.0037 0.0092 0.0215
Trichomonas vaginalis chromobox protein, putative 0.008 0.0365 0.1826
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0091 0.0434 1
Echinococcus granulosus NADH dehydrogenase 0.0037 0.0088 0.0088
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.023 0.023
Trichomonas vaginalis sucrase-isomaltase, putative 0.0084 0.0386 0.193
Mycobacterium ulcerans heat shock protein 90 0.003 0.0044 0.0133
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0027 0.0026 0.059
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.055 0.2754
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0295 0.0788
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.003 0.0044 0.0056
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0091 0.0434 0.1011
Echinococcus granulosus chromobox protein 1 0.008 0.0365 0.0365
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0125 0.0651 0.1906
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0055 0.0203 0.0613
Schistosoma mansoni methyltransferase-related 0.0109 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0142 0.0757 0.202
Echinococcus multilocularis microtubule associated protein 2 0.1596 1 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0063 0.0252 0.0252
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0091 0.0434 0.1011
Brugia malayi Pyruvate kinase, M2 isozyme 0.0038 0.0099 0.0233
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0066
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0091 0.0434 0.7655
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0069 0.0292 0.0679
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0046 0.0146 0.2579
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0386 0.2308 0.6955
Trypanosoma brucei unspecified product 0.0042 0.0122 0.0285
Toxoplasma gondii phosphomannose isomerase type I protein 0.0112 0.0567 0.2442
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0346
Loa Loa (eye worm) hypothetical protein 0.0613 0.3749 1
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0171 0.0398
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0292 0.1713 0.518
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.003 0.0044 0.1012
Entamoeba histolytica phosphomannose isomerase, putative 0.0112 0.0567 0.275
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.055 0.2753
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0543 0.3307 1
Echinococcus multilocularis pyruvate kinase 0.003 0.0047 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.1997 1
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.055 0.2753
Plasmodium falciparum endoplasmin, putative 0.0023 0 0.0006
Leishmania major mitochondrial DNA polymerase beta 0.0698 0.4295 1
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0297 0.1743 0.5235
Trypanosoma brucei heat shock protein, putative 0.0037 0.0092 0.0215
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0217 0.1232 0.1232
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.003 0.0044 0.0102
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0053 0.019 0.0574
Trypanosoma brucei heat shock protein, putative 0.0037 0.0092 0.0215
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0112 0.0567 0.2838
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.017 0.0396
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0028 0.0032 0.0074
Mycobacterium ulcerans hypothetical protein 0.0055 0.0203 0.0613
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0438 0.102
Toxoplasma gondii pyruvate kinase PyK1 0.0038 0.0099 0.0425
Toxoplasma gondii heat shock protein 90, putative 0.0037 0.0092 0.0398
Onchocerca volvulus 0.0273 0.1591 0.3879
Trichomonas vaginalis set domain proteins, putative 0.0273 0.1591 0.7966
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.1997 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.0386 0.1831
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0052 0.026
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0651 0.3259
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0055 0.0203 0.054
Trypanosoma cruzi pyruvate kinase 2, putative 0.0038 0.0099 0.023
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.055 0.2753
Trypanosoma brucei glucosidase, putative 0.0084 0.0386 0.0898
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0236 0.1353 0.5826
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0055 0.0203 0.054
Chlamydia trachomatis acyl carrier protein 0.0037 0.0088 0.2016
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.094 0.5832 0.5832
Leishmania major phosphomannose isomerase 0.0112 0.0567 0.132
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0127 0.0127
Mycobacterium tuberculosis Conserved hypothetical protein 0.0061 0.0243 0.0663
Brugia malayi jmjC domain containing protein 0.0043 0.0127 0.03
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0112 0.0567 0.1715
Brugia malayi chromobox protein homolog 3 0.0045 0.014 0.0332
Loa Loa (eye worm) hypothetical protein 0.0058 0.0222 0.0591
Schistosoma mansoni alpha-glucosidase 0.0324 0.1916 0.1916
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Schistosoma mansoni hypothetical protein 0.0024 0.0005 0.0005
Brugia malayi mbt repeat family protein 0.0055 0.0204 0.0482
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0055 0.0203 0.0613
Onchocerca volvulus 0.0649 0.3977 0.9896
Echinococcus granulosus pyruvate kinase 0.0038 0.0099 0.0099
Brugia malayi Bromodomain containing protein 0.0036 0.0085 0.0201
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0171 0.0398
Mycobacterium tuberculosis Conserved protein 0.0109 0.055 0.1598
Echinococcus multilocularis chromobox protein 1 0.008 0.0365 0.0365
Echinococcus multilocularis bloom syndrome protein 0.0052 0.0187 0.0187
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0068 0.0292
Echinococcus multilocularis endoplasmin 0.003 0.0044 0.0044
Trichomonas vaginalis maltase-glucoamylase, putative 0.0084 0.0386 0.193
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0109 0.055 0.1281
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0028 0.0034 0.0079
Trypanosoma brucei Heat shock protein 83, putative 0.0037 0.0092 0.0215
Schistosoma mansoni hypothetical protein 0.0196 0.1103 0.1103
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0096 0.0464 0.1095
Treponema pallidum acyl carrier protein 0.0037 0.0088 0.0314
Mycobacterium ulcerans 6-phosphofructokinase 0.0125 0.0651 0.1969
Entamoeba histolytica acyl-CoA synthetase, putative 0.0092 0.0436 0.2086
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0092 0.0215
Brugia malayi hypothetical protein 0.0142 0.0757 0.1789
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0052 0.026
Mycobacterium tuberculosis Conserved protein 0.0028 0.0034 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0245 0.1414 0.3292
Trypanosoma brucei DNA polymerase IV, putative 0.0084 0.039 0.0908
Plasmodium falciparum phd finger protein, putative 0.0034 0.0068 0.1198
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0053 0.019 0.0574
Trichomonas vaginalis DNA helicase recq, putative 0.0052 0.0187 0.0933
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0281
Loa Loa (eye worm) hypothetical protein 0.0274 0.1597 0.426
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0386 0.193
Echinococcus granulosus 6 phosphofructokinase 0.0125 0.0651 0.0651
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0102 0.0232
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0112 0.0567 0.134
Giardia lamblia Fructose-bisphosphate aldolase 0.0337 0.1997 1
Onchocerca volvulus 0.0035 0.0079 0.0067
Onchocerca volvulus 0.0055 0.0203 0.038
Giardia lamblia Pyruvate kinase 0.0038 0.0099 0.0281
Schistosoma mansoni acyl carrier protein 0.0037 0.0088 0.0088
Brugia malayi Pyruvate kinase, muscle isozyme 0.0038 0.0099 0.0233
Loa Loa (eye worm) hypothetical protein 0.0058 0.0221 0.0588
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.0166 0.0166
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.003 0.0044 0.0044
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0053 0.019 0.0501
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.02 0.1002
Schistosoma mansoni microtubule-associated protein tau 0.1596 1 1
Schistosoma mansoni hypothetical protein 0.0047 0.0154 0.0154
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.024 0.1382 0.4179
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0098 0.0479 0.1114
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0331 0.1956 0.4554
Schistosoma mansoni kinase 0.0056 0.0209 0.0209
Onchocerca volvulus 0.0356 0.2115 0.5201
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0068 0.1198
Echinococcus multilocularis heat shock protein 90 0.0037 0.0092 0.0092
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0056 0.0209 0.0557
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0386 0.2308 0.6955
Echinococcus multilocularis survival motor neuron protein 1 0.0274 0.1597 0.1597
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0069 0.0299
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.023 0.0535
Echinococcus multilocularis pyruvate kinase 0.0038 0.0099 0.0099
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0027 0.0026 0.011
Echinococcus multilocularis AMP dependent ligase 0.0039 0.0102 0.0102
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0088 0.0189
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0028 0.0034 0.0102
Leishmania major 4-coumarate:coa ligase-like protein 0.0055 0.0203 0.0472
Trichomonas vaginalis heat shock protein, putative 0.003 0.0044 0.0218
Brugia malayi MAP kinase sur-1 0.0059 0.023 0.0543
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0069 0.1225
Echinococcus granulosus polycomb protein SCMH1 0.0055 0.0204 0.0204
Brugia malayi Glycosyl hydrolases family 31 protein 0.0031 0.0052 0.0123
Loa Loa (eye worm) pyruvate kinase 0.0038 0.0099 0.0263
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0092 0.0438 0.2193
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0203 0.0479
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0299 0.0905
Trypanosoma cruzi heat shock protein 90, putative 0.0037 0.0092 0.0215
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0038 0.0099 0.0223
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0069 0.0222
Loa Loa (eye worm) 6-phosphofructokinase 0.0125 0.0651 0.1736
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0346
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0386 0.2308 0.6979
Mycobacterium tuberculosis Hypothetical protein 0.0109 0.055 0.1598
Mycobacterium tuberculosis Probable thioesterase TesA 0.0303 0.1779 0.5344
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0203 0.0479
Brugia malayi Heterochromatin protein 1 0.008 0.0365 0.0862
Trypanosoma brucei hypothetical protein, conserved 0.0245 0.1414 0.3292
Mycobacterium ulcerans thioesterase TesA 0.0303 0.1779 0.538
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0039 0.0102 0.0308
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0061 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0041 0.0115 0.0306
Trypanosoma brucei protein kinase, putative 0.0059 0.023 0.0535
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0162 0.0277
Trichomonas vaginalis maltase-glucoamylase, putative 0.0031 0.0052 0.026
Schistosoma mansoni chromobox protein 0.008 0.0365 0.0365
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.01 0.0228
Echinococcus multilocularis citrate lyase subunit beta protein 0.0028 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0114 0.058 0.1547
Loa Loa (eye worm) hypothetical protein 0.0142 0.0757 0.202
Giardia lamblia Kinase, PLK 0.0109 0.055 0.2592
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0166 0.0828
Echinococcus granulosus dna polymerase eta 0.0091 0.043 0.043
Schistosoma mansoni survival motor neuron protein 0.0056 0.021 0.021
Leishmania major pyruvate kinase 0.0038 0.0099 0.023
Treponema pallidum fructose-bisphosphate aldolase 0.0337 0.1997 1
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0346
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0098 0.0479 0.1114
Giardia lamblia Methyltransferase like 2 0.0109 0.055 0.2592
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0363 0.2164 0.6545
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0037 0.0088 0.0189
Trypanosoma brucei DNA polymerase IV, putative 0.0092 0.0438 0.102
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0292 0.0292
Echinococcus granulosus heat shock protein 0.0037 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0041 0.0115 0.0306
Echinococcus multilocularis jumonji domain containing protein 0.0047 0.0152 0.0152
Loa Loa (eye worm) phosphofructokinase 0.0125 0.0651 0.1736
Mycobacterium ulcerans acyl carrier protein 0.0037 0.0088 0.0265
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0052 0.026
Entamoeba histolytica acyl-coA synthetase, putative 0.0055 0.0203 0.0903
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0243 0.0575
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0299 0.0299
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0363 0.2164 0.6518
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0222 0.0524
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0118 0.0118
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.023 0.115
Loa Loa (eye worm) hypothetical protein 0.0034 0.0068 0.0181
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0063 0.0252 0.0596
Mycobacterium ulcerans DNA polymerase IV 0.0092 0.0438 0.1325
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0028 0.0034 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0299 0.0905
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0028 0.0034 0.0167
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0052 0.0139
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.023 0.0535
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0037 0.0088 0.0204
Leishmania major hypothetical protein, conserved 0.0245 0.1414 0.3292
Trypanosoma brucei DNA polymerase eta, putative 0.0091 0.043 0.1001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.021
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0055 0.0203 0.0613
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0052 0.0121
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0091 0.0434 0.1011
Leishmania major pyruvate kinase 0.0038 0.0099 0.023
Echinococcus multilocularis dna polymerase eta 0.0091 0.043 0.043
Mycobacterium ulcerans pyruvate kinase 0.0038 0.0099 0.0299
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.023 0.099
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0092 0.0215
Echinococcus multilocularis expressed conserved protein 0.0107 0.0536 0.0536
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0543 0.3307 1
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0386 0.2308 0.6955
Onchocerca volvulus Pyruvate kinase homolog 0.0038 0.0099 0.0117
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.019 0.0574
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.023 0.115
Brugia malayi PHD-finger family protein 0.0029 0.0037 0.0087
Echinococcus multilocularis Niemann Pick C1 protein 0.0114 0.058 0.058
Trypanosoma brucei heat shock protein, putative 0.0037 0.0092 0.0215
Brugia malayi Bloom's syndrome protein homolog 0.0052 0.0187 0.0441
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0363 0.2164 0.6518
Loa Loa (eye worm) hypothetical protein 0.0055 0.0203 0.0541
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0028 0.0034 0.0102
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0112 0.0567 0.0567
Toxoplasma gondii type I fatty acid synthase, putative 0.0388 0.2322 1
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0198 0.0198
Loa Loa (eye worm) heat shock protein 90 0.0037 0.0092 0.0247
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0186 0.1036 0.4461
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0346
Schistosoma mansoni blooms syndrome DNA helicase 0.0041 0.0117 0.0117
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0303 0.1779 0.5344
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0091 0.0434 0.0434
Toxoplasma gondii heat shock protein HSP90 0.0037 0.0092 0.0398
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0112 0.0567 0.1512
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0105 0.0249
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0044 0.0102
Trichomonas vaginalis heat shock protein, putative 0.0037 0.0092 0.0461
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0056 0.0209 0.0557
Loa Loa (eye worm) pyruvate kinase 0.0038 0.0099 0.0263
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0698 0.4295 1
Echinococcus granulosus lysosomal alpha glucosidase 0.0377 0.225 0.225
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0203 0.0613
Trichomonas vaginalis DNA helicase recq, putative 0.0028 0.0032 0.0157
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0352 0.2094 0.6302
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0283
Echinococcus multilocularis protein patched 0.0049 0.0166 0.0166
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.003 0.0044 0.0056
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0386 0.193
Trypanosoma brucei heat shock protein, putative 0.0037 0.0092 0.0215
Echinococcus granulosus PHD finger protein rhinoceros 0.0034 0.0068 0.0068
Entamoeba histolytica acyl-CoA synthetase, putative 0.0039 0.0102 0.0391
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.011 0.0554 0.0554
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0028 0.0034 0.0079
Echinococcus multilocularis lysine specific demethylase 5A 0.0041 0.0113 0.0113
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0035 0.0076 0.0328
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0116 0.0591 0.0591
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0091 0.0434 0.1011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0203 0.054
Schistosoma mansoni hypothetical protein 0.0034 0.0068 0.0068
Loa Loa (eye worm) PHD-finger family protein 0.0034 0.0068 0.0181
Echinococcus granulosus jumonji domain containing protein 0.0047 0.0152 0.0152
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0112 0.0567 1
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0112 0.0564 0.1642
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.0044 0.0102
Brugia malayi polk-prov protein 0.005 0.017 0.0401
Leishmania major DNA polymerase eta, putative 0.0048 0.0162 0.0376
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.021 0.0495
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0091 0.0434 0.1312
Mycobacterium ulcerans polyketide synthase 0.0363 0.2164 0.6545
Leishmania major ATP-dependent phosphofructokinase 0.0125 0.0651 0.1516
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0363 0.2164 0.5113
Loa Loa (eye worm) hypothetical protein 0.0041 0.0115 0.0306
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0346
Schistosoma mansoni hypothetical protein 0.0196 0.1103 0.1103
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0061 0.0243 0.0649
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0203 0.0613
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.014 0.0702
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0027 0.0026 0.011
Mycobacterium ulcerans polyketide synthase MbtC 0.0091 0.0434 0.1312
Onchocerca volvulus 0.0053 0.019 0.0347
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0041 0.0115 0.2641
Schistosoma mansoni hypothetical protein 0.0047 0.0154 0.0154
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.1997 1
Plasmodium falciparum heat shock protein 90 0.0037 0.0092 0.163
Loa Loa (eye worm) hypothetical protein 0.0044 0.0135 0.0361
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0203 0.0613
Mycobacterium leprae Probable pyruvate kinase PykA 0.0038 0.0099 0.0223
Loa Loa (eye worm) hypothetical protein 0.0045 0.014 0.0375
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0386 0.2308 0.6979
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0061 0.0241 0.0655
Toxoplasma gondii type I fatty acid synthase 0.0056 0.0209 0.0898
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0091 0.0434 0.1158
Brugia malayi AMP-binding enzyme family protein 0.0114 0.0579 0.1367
Toxoplasma gondii acyl carrier protein ACP 0.0037 0.0088 0.0377
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0069 0.16
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0069 0.0131
Loa Loa (eye worm) pyruvate kinase-PB 0.0027 0.0025 0.0066
Brugia malayi Methyltransferase-like protein 4 0.0109 0.055 0.13
Schistosoma mansoni hypothetical protein 0.0037 0.0088 0.0088
Trypanosoma cruzi phosphomannose isomerase, putative 0.0112 0.0567 0.132
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0203 0.0479
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.01 0.0228
Loa Loa (eye worm) pyruvate kinase 0.0038 0.0099 0.0263
Trypanosoma brucei phosphomannose isomerase 0.0112 0.0567 0.132
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.01 0.0228
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.01 0.0228
Brugia malayi PHD-finger family protein 0.0034 0.0068 0.016
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.023 0.0535
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0386 0.193
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0028 0.0034 0.0102
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0037 0.0088 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.023 0.023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.1997 1
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0052 0.0121
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.023 0.115
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0091 0.0434 0.1025
Entamoeba histolytica recQ family helicase, putative 0.0028 0.0032 0.0036
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0052 0.026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0127 0.0127
Loa Loa (eye worm) mbt repeat family protein 0.0055 0.0204 0.0544
Echinococcus granulosus SAM and MBT domain containing protein 0.0055 0.0204 0.0204
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.1997 1
Onchocerca volvulus Fatty acid synthase homolog 0.0655 0.4019 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0052 0.026
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0299 0.0299
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0041 0.0115 0.0347
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.055 0.2753
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.0166 0.0442
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0019 0.0019
Echinococcus granulosus bloom syndrome protein 0.0052 0.0187 0.0187
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0091 0.0434 1
Mycobacterium ulcerans hypothetical protein 0.0028 0.0034 0.0102
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0299 0.1289
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0039 0.0102 0.0308
Mycobacterium ulcerans polyketide synthase MbtD 0.0112 0.0564 0.1707
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0051 0.0181 0.079
Schistosoma mansoni pyruvate kinase 0.0038 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0031 0.0052 0.0139
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0118 0.0118
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0069 0.16
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0027 0.0023 0.01
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0331 0.1956 0.4554
Echinococcus multilocularis chromobox protein 1 0.008 0.0365 0.0365
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0651 0.3176
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0037 0.0088 0.0189
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0052 0.026
Trypanosoma brucei unspecified product 0.0042 0.0122 0.0285
Trypanosoma brucei pyruvate kinase 1, putative 0.0038 0.0099 0.023
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0028 0.0032 0.0074
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0109 0.055 0.1467
Mycobacterium leprae Probable polyketide synthase Pks1 0.0386 0.2308 0.6955
Brugia malayi Pre-SET motif family protein 0.0034 0.0073 0.0172
Schistosoma mansoni heat shock protein 0.0037 0.0092 0.0092
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0048 0.0157 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.017 0.0396
Echinococcus multilocularis NADH dehydrogenase 0.0037 0.0088 0.0088
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0204 0.0204
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0204 0.0204
Echinococcus granulosus L aminoadipate semialdehyde 0.0096 0.0464 0.0464
Echinococcus granulosus citrate lyase subunit beta protein 0.0028 0.0034 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0386 0.193
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0651 0.3176
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.0166 0.0166
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0165 0.0901 0.2667
Loa Loa (eye worm) hypothetical protein 0.005 0.017 0.0453
Brugia malayi Bromodomain containing protein 0.0044 0.0135 0.0319
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0056 0.0209 0.0557
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0005 0.0015
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0037 0.0088 0.0089
Schistosoma mansoni DNA polymerase eta 0.0091 0.043 0.043
Loa Loa (eye worm) acyl carrier protein 0.0037 0.0088 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0057 0.0283
Mycobacterium ulcerans polyketide synthase 0.0386 0.2308 0.6979
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0055 0.0204 0.0382
Echinococcus granulosus heat shock protein 90 0.003 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0054 0.0198 0.0528
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0438 0.102
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Giardia lamblia Heat shock protein HSP 90-alpha 0.0037 0.0092 0.0248
Echinococcus multilocularis lysosomal alpha glucosidase 0.0377 0.225 0.225
Brugia malayi serine/threonine-protein kinase plk-2 0.0109 0.055 0.1299
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0203 0.0613
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0292 0.0292
Trypanosoma cruzi Heat shock protein 83, putative 0.0037 0.0092 0.0215
Giardia lamblia DINP protein human, muc B family 0.0069 0.0292 0.1268
Entamoeba histolytica serine/threonine protein kinase, putative 0.0109 0.055 0.2664
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0026 0.0452
Echinococcus multilocularis 6 phosphofructokinase 0.0125 0.0651 0.0651
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0438 0.102
Schistosoma mansoni myelin transcription factor 1 myt1 0.0063 0.0252 0.0252
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0159 0.0865 0.2306
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.024 0.138 0.368
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0053 0.019 0.0501
Brugia malayi Glycosyl hydrolases family 31 protein 0.0084 0.0386 0.0911
Brugia malayi CHE-14 protein 0.0049 0.0166 0.0391
Trypanosoma brucei heat shock protein, putative 0.0037 0.0092 0.0215
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0028 0.0034 0.0079
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0091 0.0434 0.1312
Mycobacterium ulcerans fatty acid synthase Fas 0.0114 0.058 0.1753
Trypanosoma cruzi DNA polymerase kappa, putative 0.0092 0.0438 0.102
Echinococcus granulosus Niemann Pick C1 protein 0.0163 0.0891 0.0891
Mycobacterium ulcerans Type I modular polyketide synthase 0.0363 0.2164 0.6545
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0125 0.0651 0.1516
Mycobacterium ulcerans Type I modular polyketide synthase 0.0363 0.2164 0.6545
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.023 0.023
Echinococcus granulosus neutral alpha glucosidase AB 0.0084 0.0386 0.0386
Schistosoma mansoni terminal deoxycytidyl transferase 0.0061 0.0243 0.0243
Echinococcus granulosus survival motor neuron protein 1 0.0274 0.1597 0.1597
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0084 0.0386 0.1661
Brugia malayi phosphofructokinase 0.0125 0.0651 0.1538
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0034 0.0068 0.0068
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0125 0.0651 0.1516
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0027 0.0026 0.0077
Schistosoma mansoni bromodomain containing protein 0.0073 0.0318 0.0318
Brugia malayi Glycosyl hydrolases family 31 protein 0.0377 0.225 0.5314
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.023 0.115
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.055 0.2753
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0109 0.055 0.055
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0112 0.0567 0.1512
Loa Loa (eye worm) RecQ helicase 0.0052 0.0187 0.0498
Trypanosoma brucei glycosyl hydrolase-like protein 0.0031 0.0052 0.0121
Schistosoma mansoni patched 1 0.0049 0.0166 0.0166
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0651 0.3176
Onchocerca volvulus 0.0056 0.021 0.0397
Echinococcus granulosus endoplasmin 0.003 0.0044 0.0044
Schistosoma mansoni alpha-glucosidase 0.0324 0.1916 0.1916
Brugia malayi jmjC domain containing protein 0.011 0.0554 0.1309
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0222 0.0524
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0438 0.102
Loa Loa (eye worm) fatty acid synthase 0.0359 0.2134 0.5691
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0292 0.1713 0.5142
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0207 0.1168 0.348
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0438 0.102
Trypanosoma cruzi DNA polymerase eta, putative 0.0091 0.043 0.1001
Schistosoma mansoni alpha glucosidase 0.0084 0.0386 0.0386
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.0386 0.193
Brugia malayi AMP-binding enzyme family protein 0.0356 0.2115 0.4996
Echinococcus multilocularis PHD finger protein rhinoceros 0.0034 0.0068 0.0068
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0061 0.0243 0.0243
Echinococcus granulosus Niemann Pick C1 protein 0.0114 0.058 0.058
Toxoplasma gondii hypothetical protein 0.0113 0.057 0.2456
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0689 0.4233 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0263
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.023 0.023
Mycobacterium ulcerans polyketide synthase Pks9 0.024 0.1382 0.4179
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0035 0.0079 0.1392
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0162 0.0811
Leishmania major DNA polymerase kappa, putative 0.0069 0.0292 0.0679
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0105
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0019 0.0019
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.0198 0.0198
Onchocerca volvulus Serine\/threonine kinase homolog 0.0109 0.055 0.1255
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0299 0.0697
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.012 0.0615 0.1432
Loa Loa (eye worm) hypothetical protein 0.0056 0.0209 0.0556
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0037 0.0088 0.0189
Echinococcus multilocularis geminin 0.0196 0.1103 0.1103
Loa Loa (eye worm) MBCTL1 0.0063 0.0252 0.0673
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0037 0.0088 0.0233
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0651 0.3259
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0053 0.019 0.0501
Brugia malayi ImpB/MucB/SamB family protein 0.0091 0.043 0.1016
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.023 0.0535
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.0198 0.0198
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0069 0.0299
Loa Loa (eye worm) hypothetical protein 0.0047 0.0153 0.0408
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0102 0.0232
Trypanosoma brucei pyruvate kinase 1 0.0038 0.0099 0.023
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0053 0.019 0.0449
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0337 0.1997 1
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0056 0.0209 0.0557
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0048 0.0162 0.0696
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.1997 1
Echinococcus multilocularis dna polymerase kappa 0.0092 0.0438 0.0438
Leishmania major acyl carrier protein, putative 0.0037 0.0088 0.0204
Echinococcus granulosus expressed conserved protein 0.0107 0.0536 0.0536
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0127 0.0338
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0651 0.3259
Echinococcus multilocularis pyruvate kinase 0.0038 0.0099 0.0099
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.055 0.2753
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0346
Leishmania major 4-coumarate:coa ligase-like protein 0.0055 0.0203 0.0472
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0027 0.0026 0.059
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0091 0.0434 0.0434
Entamoeba histolytica hypothetical protein 0.0027 0.0026 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0299 0.0905
Loa Loa (eye worm) hypothetical protein 0.0055 0.0203 0.0541
Loa Loa (eye worm) hypothetical protein 0.006 0.0236 0.0629
Plasmodium falciparum acyl-CoA synthetase 0.0041 0.0115 0.2022
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0386 0.2308 0.6955
Trypanosoma cruzi DNA polymerase kappa, putative 0.0092 0.0438 0.102
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0061 0.0241 0.0655
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0091 0.0434 0.1869
Brugia malayi Niemann-Pick C1 protein precursor 0.0114 0.058 0.137
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0084 0.0386 0.1029
Echinococcus multilocularis L aminoadipate semialdehyde 0.0096 0.0464 0.0464
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0165 0.0901 0.2667
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Echinococcus granulosus chromobox protein 1 0.008 0.0365 0.0365
Plasmodium vivax endoplasmin, putative 0.0037 0.0092 0.163
Schistosoma mansoni hypothetical protein 0.0047 0.0154 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0171 0.0398
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0069 0.1225
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0125 0.0651 0.1906
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0198 0.0198
Mycobacterium ulcerans polyketide synthase Pks13 0.0543 0.3307 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0252 0.0673
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0069 0.1225
Mycobacterium ulcerans Type I modular polyketide synthase 0.0363 0.2164 0.6545
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0162 0.0811
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0068 0.0292
Trichomonas vaginalis chromobox protein, putative 0.008 0.0365 0.1826
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0092 0.0215
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0026 0.0452
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0299 0.0299
Brugia malayi heat shock protein 90 0.0037 0.0092 0.0218
Loa Loa (eye worm) hypothetical protein 0.0082 0.0373 0.0994
Trichomonas vaginalis heat shock protein, putative 0.003 0.0044 0.0218
Trypanosoma cruzi DNA polymerase kappa, putative 0.0092 0.0438 0.102
Echinococcus granulosus geminin 0.0196 0.1103 0.1103
Entamoeba histolytica deoxycytidyl transferase, putative 0.0061 0.0243 0.1108
Trypanosoma cruzi DNA polymerase kappa, putative 0.0092 0.0438 0.102
Echinococcus multilocularis protein dispatched 1 0.0056 0.021 0.021
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.023 0.0535
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0292 0.0679
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0073 0.0073
Trypanosoma brucei heat shock protein, putative 0.0037 0.0092 0.0215
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0125 0.0651 0.3173
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0053 0.019 0.0574
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0125 0.0648 0.1898
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0052 0.026
Trichomonas vaginalis heat shock protein, putative 0.003 0.0044 0.0218
Loa Loa (eye worm) endoplasmin 0.0037 0.0092 0.0247
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0112 0.0567 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0069 0.0292 0.0811
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0088 0.0189
Mycobacterium ulcerans hypothetical protein 0.0028 0.0034 0.0102
Echinococcus multilocularis heat shock protein 0.0037 0.0092 0.0092
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0386 0.0898
Echinococcus granulosus pyruvate kinase 0.0038 0.0099 0.0099
Echinococcus granulosus acyl carrier protein mitochondrial 0.0037 0.0088 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0438 0.102
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0356 0.2115 0.6367
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0147 0.0788 0.2325
Onchocerca volvulus 0.0055 0.0204 0.0382
Brugia malayi 6-phosphofructokinase 0.0125 0.0651 0.1538
Echinococcus granulosus dna polymerase kappa 0.0092 0.0438 0.0438
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0053 0.019 0.0501
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.055 0.1281
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0386 0.2308 0.6955
Onchocerca volvulus Pyruvate kinase homolog 0.0038 0.0099 0.0117
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.023 0.0535
Loa Loa (eye worm) acyl carrier protein 0.0167 0.0916 0.2444
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0069 0.0346
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0114 0.058 0.2815
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0073 0.0314
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.1997 1
Trypanosoma brucei DNA polymerase IV, putative 0.0092 0.0438 0.102
Mycobacterium ulcerans hypothetical protein 0.0037 0.0088 0.0265
Trichomonas vaginalis pyruvate kinase, putative 0.0038 0.0099 0.0493
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.023 0.023
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.023 0.0613
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0386 0.193
Loa Loa (eye worm) hypothetical protein 0.0049 0.0167 0.0445
Trypanosoma cruzi phosphomannose isomerase, putative 0.0112 0.0567 0.132
Leishmania major hypothetical protein, conserved 0.0109 0.055 0.1281
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0109 0.055 0.055
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0037 0.0088 0.2016
Mycobacterium ulcerans hypothetical protein 0.0368 0.2193 0.6632
Schistosoma mansoni endoplasmin 0.0037 0.0092 0.0092
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0041 0.0115 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.055 0.055
Schistosoma mansoni endoplasmin 0.0037 0.0092 0.0092
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0363 0.2164 0.6518
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0112 0.0567 0.134
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0698 0.4295 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.0438 0.102
Entamoeba histolytica acyl-CoA synthetase, putative 0.0055 0.0203 0.0903
Onchocerca volvulus Pyruvate kinase homolog 0.0038 0.0099 0.0117
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0299 0.0834
Treponema pallidum heat shock protein 90 0.003 0.0044 0.0093
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0337 0.1997 1
Schistosoma mansoni jumonji domain containing protein 0.0087 0.041 0.041
Schistosoma mansoni 6-phosphofructokinase 0.0125 0.0651 0.0651
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0127 0.0127
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0037 0.0088 0.0088
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0069 0.0227
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Trypanosoma brucei unspecified product 0.0084 0.039 0.0908
Trypanosoma brucei heat shock protein, putative 0.0037 0.0092 0.0215
Plasmodium vivax pyruvate kinase, putative 0.0038 0.0099 0.1741
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.0386 0.193
Trichomonas vaginalis pyruvate kinase, putative 0.0038 0.0099 0.0493
Leishmania major heat shock protein 83-1 0.0037 0.0092 0.0215
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0337 0.1997 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.023 0.0535
Echinococcus multilocularis heat shock protein 90 0.003 0.0044 0.0044
Leishmania major glycosyl hydrolase-like protein 0.0031 0.0052 0.0121
Leishmania major phosphopantetheinyl transferase-like protein 0.0027 0.0026 0.006
Echinococcus granulosus peregrin 0.0036 0.0085 0.0085
Schistosoma mansoni chromobox protein 0.008 0.0365 0.0365

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -5.735 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.611 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.983 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.953 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.847 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.754 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.749 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.726 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.703 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.566 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.393 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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