Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0038 | 0.0128 | 0.0128 |
Brugia malayi | hypothetical protein | 0.0447 | 0.3023 | 0.3023 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0058 | 0.0267 | 0.0267 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0038 | 0.0128 | 0.0128 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.036 | 0.1459 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0824 | 0.5692 | 0.5692 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0038 | 0.0128 | 0.0128 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0028 | 0.0056 | 0.0297 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0004 | 0.0004 |
Echinococcus multilocularis | RUN | 0.1433 | 1 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0031 | 0.0076 | 0.0444 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0152 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.036 | 0.036 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0398 | 0.2674 | 0.2674 |
Schistosoma mansoni | tar DNA-binding protein | 0.0398 | 0.2674 | 0.2674 |
Schistosoma mansoni | alkaline phosphatase | 0.1025 | 0.7116 | 0.7116 |
Brugia malayi | hypothetical protein | 0.0205 | 0.1309 | 0.1309 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0048 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0128 | 0.0128 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0024 | 0.0028 | 0.0028 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0197 | 0.0197 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0113 | 0.0113 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0038 | 0.0128 | 0.0128 |
Plasmodium falciparum | LCCL domain-containing protein | 0.1433 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0211 | 0.0211 |
Schistosoma mansoni | tar DNA-binding protein | 0.0398 | 0.2674 | 0.2674 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0089 | 0.0488 | 0.0488 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0216 | 0.1387 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.005 | 0.0211 | 0.0211 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0075 | 0.0389 | 0.0389 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.0557 | 0.0557 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | heat shock protein | 0.0028 | 0.0056 | 0.0056 |
Brugia malayi | Bromodomain containing protein | 0.0081 | 0.0428 | 0.0428 |
Echinococcus granulosus | alkaline phosphatase | 0.1025 | 0.7116 | 0.7116 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0113 | 0.0113 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | hypothetical protein | 0.0533 | 0.3628 | 0.3628 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0191 | 0.1211 | 0.1211 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0076 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.005 | 0.0211 | 0.0211 |
Schistosoma mansoni | zinc finger protein | 0.0025 | 0.0032 | 0.0032 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Brugia malayi | nuclear receptor NHR-88 | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0048 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.0244 | 0.0244 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0158 | 0.0976 | 0.0976 |
Echinococcus granulosus | tar DNA binding protein | 0.0398 | 0.2674 | 0.2674 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0205 | 0.1309 | 0.1309 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0038 | 0.0128 | 0.0128 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.036 | 0.1459 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0158 | 0.0976 | 0.0976 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.0244 | 0.0244 |
Schistosoma mansoni | thyroid hormone receptor | 0.0038 | 0.0128 | 0.0128 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0216 | 0.1387 | 0.4566 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | hypothetical protein | 0.0108 | 0.0622 | 0.0622 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Brugia malayi | Pre-SET motif family protein | 0.0393 | 0.2637 | 0.2637 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.0244 | 0.0244 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 0.7083 |
Onchocerca volvulus | 0.1433 | 1 | 1 | |
Echinococcus multilocularis | cpg binding protein | 0.0096 | 0.0538 | 0.0538 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0211 | 0.0211 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 0.7083 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.036 | 0.1459 |
Echinococcus granulosus | dnaJ subfamily B | 0.0824 | 0.5692 | 0.5692 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0447 | 0.3023 | 0.3023 |
Onchocerca volvulus | 0.0089 | 0.0488 | 0.0364 | |
Loa Loa (eye worm) | DEAH box polypeptide 35 | 0.0142 | 0.0861 | 0.0861 |
Toxoplasma gondii | NAC domain-containing protein | 0.0216 | 0.1387 | 1 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0031 | 0.0076 | 0.002 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.1025 | 0.7116 | 0.7116 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0147 | 0.0147 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Brugia malayi | isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0076 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0076 | 0.0444 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0205 | 0.1309 | 0.1309 |
Brugia malayi | ecdysteroid receptor | 0.0038 | 0.0128 | 0.0128 |
Onchocerca volvulus | 0.0048 | 0.0197 | 0.007 | |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0398 | 0.2674 | 0.2674 |
Brugia malayi | Isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0076 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0211 | 0.0211 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0031 | 0.0076 | 0.0636 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0211 | 0.0211 |
Echinococcus multilocularis | Protein lozenge | 0.0056 | 0.0253 | 0.0253 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0048 | 0.0197 | 0.0197 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0058 | 0.0267 | 0.1585 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0108 | 0.0622 | 0.0622 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0038 | 0.0128 | 0.0128 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0216 | 0.1387 | 0.4566 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0362 | 0.0362 |
Schistosoma mansoni | cpg binding protein | 0.0089 | 0.0488 | 0.0488 |
Schistosoma mansoni | coup transcription factor | 0.0038 | 0.0128 | 0.0128 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.029 | 0.2873 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0038 | 0.0128 | 0.0128 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0447 | 0.3023 | 0.3023 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0058 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.005 | 0.0211 | 0.0211 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.0244 | 0.0244 |
Schistosoma mansoni | rab6-interacting | 0.1433 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0398 | 0.2674 | 0.2674 |
Schistosoma mansoni | hypothetical protein | 0.0297 | 0.1957 | 0.1957 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0054 | 0.0238 | 0.0238 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0028 | 0.0056 | 0.0135 |
Loa Loa (eye worm) | runx1 | 0.0056 | 0.0253 | 0.0253 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.029 | 0.2007 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0128 | 0.0128 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.1025 | 0.7116 | 0.7116 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0071 | 0.036 | 0.036 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0038 | 0.0128 | 0.0128 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.0557 | 0.0557 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.0557 | 0.0557 |
Schistosoma mansoni | bromodomain containing protein | 0.0069 | 0.0345 | 0.0345 |
Loa Loa (eye worm) | TAR-binding protein | 0.0398 | 0.2674 | 0.2674 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.1025 | 0.7116 | 0.7116 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0038 | 0.0128 | 0.0128 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0038 | 0.0128 | 0.0128 |
Echinococcus multilocularis | tar DNA binding protein | 0.0398 | 0.2674 | 0.2674 |
Echinococcus granulosus | geminin | 0.0662 | 0.4542 | 0.4542 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0038 | 0.0128 | 0.0128 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | tar DNA-binding protein | 0.0398 | 0.2674 | 0.2674 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.029 | 0.1762 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0028 | 0.0056 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0197 | 0.0197 |
Echinococcus granulosus | heat shock protein 90 | 0.0028 | 0.0056 | 0.0056 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Onchocerca volvulus | 0.0058 | 0.0267 | 0.014 | |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0048 | 0.0197 | 0.007 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0131 | 0.0131 |
Echinococcus granulosus | GPCR family 2 | 0.005 | 0.0211 | 0.0211 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0197 | 0.0197 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0022 | 0.0015 | 0.0015 |
Echinococcus multilocularis | endoplasmin | 0.0022 | 0.0015 | 0.0015 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | doublecortin family protein | 0.1433 | 1 | 1 |
Brugia malayi | Endoplasmin precursor | 0.0028 | 0.0056 | 0.0056 |
Brugia malayi | Probable ATP-dependent helicase DHX35 | 0.0142 | 0.0861 | 0.0861 |
Loa Loa (eye worm) | RNA binding protein | 0.0398 | 0.2674 | 0.2674 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0065 | 0.0319 | 0.0319 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.036 | 0.1459 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0038 | 0.0128 | 0.0128 |
Echinococcus granulosus | endoplasmin | 0.0022 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0197 | 0.0197 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0099 | 0.0557 | 0.0557 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.0557 | 0.0557 |
Echinococcus multilocularis | heat shock protein | 0.0028 | 0.0056 | 0.0056 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.0244 | 0.0244 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.029 | 0.2873 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0076 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0128 | 0.0128 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0004 | 0.0004 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Schistosoma mansoni | tar DNA-binding protein | 0.0398 | 0.2674 | 0.2674 |
Schistosoma mansoni | nuclear hormone receptor | 0.0038 | 0.0128 | 0.0128 |
Onchocerca volvulus | 0.0042 | 0.0152 | 0.0024 | |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0028 | 0.0056 | 0.0191 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0038 | 0.0128 | 0.0128 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0038 | 0.0128 | 0.0128 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0216 | 0.1387 | 0.4566 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0048 | 0.0197 | 0.0197 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0158 | 0.0973 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0096 | 0.0538 | 0.0538 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.1433 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1433 | 1 | 1 |
Echinococcus multilocularis | zinc finger protein | 0.0025 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | endoplasmin | 0.0028 | 0.0056 | 0.0056 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0076 | 0.0152 |
Loa Loa (eye worm) | histone methyltransferase | 0.003 | 0.0066 | 0.0066 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.005 | 0.0211 | 0.0211 |
Schistosoma mansoni | alkaline phosphatase | 0.1025 | 0.7116 | 0.7116 |
Brugia malayi | hypothetical protein | 0.0071 | 0.036 | 0.036 |
Schistosoma mansoni | heat shock protein | 0.0028 | 0.0056 | 0.0056 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.0557 | 0.0557 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.029 | 0.029 |
Echinococcus granulosus | heat shock protein | 0.0028 | 0.0056 | 0.0056 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0028 | 0.0053 | 0.0053 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Schistosoma mansoni | hypothetical protein | 0.0824 | 0.5692 | 0.5692 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0024 | 0.0028 | 0.0028 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0024 | 0.0028 | 0.0028 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0099 | 0.0557 | 0.0557 |
Brugia malayi | steroid hormone receptor | 0.0038 | 0.0128 | 0.0128 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.007 | 0.007 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0075 | 0.0389 | 0.0389 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.029 | 0.029 |
Echinococcus granulosus | heat shock protein 90 | 0.0022 | 0.0015 | 0.0015 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.0244 | 0.0244 |
Echinococcus granulosus | transcription factor btf3 | 0.0216 | 0.1387 | 0.1387 |
Schistosoma mansoni | endoplasmin | 0.0028 | 0.0056 | 0.0056 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 0.7083 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0076 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0194 | 0.1227 | 0.1227 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0599 | 0.4095 | 0.4095 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0038 | 0.0128 | 0.0128 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0024 | 0.0028 | 0.0028 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 0.7083 |
Loa Loa (eye worm) | ICD-1 protein | 0.0216 | 0.1387 | 0.1387 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0158 | 0.0973 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.005 | 0.0211 | 0.0211 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0244 | 0.0244 |
Schistosoma mansoni | cpg binding protein | 0.0096 | 0.0538 | 0.0538 |
Schistosoma mansoni | survival motor neuron protein | 0.0042 | 0.0152 | 0.0152 |
Onchocerca volvulus | 0.0447 | 0.3019 | 0.2928 | |
Echinococcus multilocularis | GPCR, family 2 | 0.005 | 0.0211 | 0.0211 |
Schistosoma mansoni | loxhd1 | 0.1433 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.029 | 0.029 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0173 | 0.1085 | 0.7731 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1309 | 0.1309 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0031 | 0.0077 | 0.0077 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0007 | 0.0007 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0216 | 0.1387 | 0.6377 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0861 | 0.0861 |
Entamoeba histolytica | hypothetical protein | 0.0216 | 0.1387 | 0.6377 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0038 | 0.0128 | 0.0128 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0076 |
Brugia malayi | nuclear hormone receptor | 0.0038 | 0.0128 | 0.0128 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0028 | 0.0056 | 0.0297 |
Brugia malayi | hypothetical protein | 0.1433 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0038 | 0.0128 | 0.0128 |
Onchocerca volvulus | 0.1433 | 1 | 1 | |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0038 | 0.0128 | 0.0128 |
Plasmodium vivax | SET domain protein, putative | 0.0058 | 0.0267 | 0.0212 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0216 | 0.1387 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0038 | 0.0128 | 0.0128 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0024 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0389 | 0.0389 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0028 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.0976 | 0.0976 |
Schistosoma mansoni | lozenge | 0.0056 | 0.0253 | 0.0253 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0075 | 0.0389 | 0.0389 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0028 | 0.0056 | 0.0056 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0038 | 0.0128 | 0.0128 |
Leishmania major | basic transcription factor 3a, putative | 0.0216 | 0.1387 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0071 | 0.036 | 0.036 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0038 | 0.0128 | 0.0128 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0038 | 0.0128 | 0.0128 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0038 | 0.0128 | 0.0128 |
Onchocerca volvulus | 0.0447 | 0.3023 | 0.2933 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0038 | 0.0128 | 0.0128 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0031 | 0.0076 | 0.0076 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0152 | 0.0152 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0065 | 0.0319 | 0.0319 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0076 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.005 | 0.0211 | 0.0211 |
Schistosoma mansoni | hypothetical protein | 0.0662 | 0.4542 | 0.4542 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.1433 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0096 | 0.0538 | 0.0538 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0038 | 0.0128 | 0.0128 |
Brugia malayi | TAR-binding protein | 0.0398 | 0.2674 | 0.2674 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0058 | 0.0267 | 0.0267 |
Brugia malayi | Pre-SET motif family protein | 0.0058 | 0.0267 | 0.0267 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0599 | 0.4095 | 0.4095 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.029 | 0.2873 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 0.7083 |
Schistosoma mansoni | polycystin 1-related | 0.1433 | 1 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.013 | 0.013 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0197 | 0.0197 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0038 | 0.0128 | 0.0128 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.003 | 0.0066 | 0.0066 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0022 | 0.0015 | 0.5 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0076 | 0.0444 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0042 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0622 | 0.0622 |
Echinococcus multilocularis | alkaline phosphatase | 0.1025 | 0.7116 | 0.7116 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0323 | 0.2143 | 1 |
Schistosoma mansoni | transcription factor btf3 | 0.0216 | 0.1387 | 0.1387 |
Trichomonas vaginalis | set domain proteins, putative | 0.0447 | 0.3019 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0038 | 0.0128 | 0.0128 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0031 | 0.0076 | 0.002 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.003 | 0.0066 | 0.0066 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0076 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0393 | 0.2637 | 0.2637 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0197 | 0.0197 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Echinococcus multilocularis | geminin | 0.0662 | 0.4542 | 0.4542 |
Schistosoma mansoni | thyroid hormone receptor | 0.0038 | 0.0128 | 0.0128 |
Brugia malayi | hypothetical protein | 0.1433 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.0557 | 0.0557 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 0.7083 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.1433 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0038 | 0.0128 | 0.0128 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0031 | 0.0076 | 0.0152 |
Schistosoma mansoni | lipoxygenase | 0.1433 | 1 | 1 |
Brugia malayi | beta-NAC-like protein | 0.0216 | 0.1387 | 0.1387 |
Echinococcus granulosus | intestinal type alkaline phosphatase | 0.1025 | 0.7116 | 0.7116 |
Loa Loa (eye worm) | hypothetical protein | 0.1433 | 1 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.1433 | 1 | 1 |
Echinococcus multilocularis | transcription factor btf3 | 0.0216 | 0.1387 | 0.1387 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0038 | 0.0128 | 0.0128 |
Echinococcus multilocularis | heat shock protein 90 | 0.0028 | 0.0056 | 0.0056 |
Echinococcus granulosus | RUN | 0.1433 | 1 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0599 | 0.4095 | 0.4095 |
Schistosoma mansoni | tar DNA-binding protein | 0.0398 | 0.2674 | 0.2674 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0028 | 0.0056 | 0.0297 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.0557 | 0.0557 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0038 | 0.0128 | 0.0128 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0028 | 0.0053 | 0.0053 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 0.7083 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0038 | 0.0128 | 0.0128 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.029 | 0.2873 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.1025 | 0.7116 | 0.7116 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0075 | 0.0389 | 0.0389 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.1025 | 0.7116 | 0.7116 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0216 | 0.1387 | 1 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0048 | 0.0197 | 0.0197 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.029 | 0.029 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0158 | 0.0976 | 0.0976 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0128 | 0.0128 |
Echinococcus multilocularis | heat shock protein 90 | 0.0022 | 0.0015 | 0.0015 |
Echinococcus granulosus | zinc finger protein | 0.0025 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0128 | 0.0128 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0028 | 0.0056 | 0.0297 |
Schistosoma mansoni | hypothetical protein | 0.0662 | 0.4542 | 0.4542 |
Schistosoma mansoni | rab6-interacting | 0.1433 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0038 | 0.0128 | 0.0128 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0216 | 0.1387 | 0.1338 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0038 | 0.0128 | 0.0128 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0216 | 0.1387 | 0.1338 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.2143 | 0.7083 |
Echinococcus granulosus | FTZ F1 alpha | 0.0038 | 0.0128 | 0.0128 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0194 | 0.1227 | 0.1227 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0071 | 0.036 | 0.036 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0076 | 0.0076 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0211 | 0.0211 |
Schistosoma mansoni | hypothetical protein | 0.1433 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0038 | 0.0128 | 0.0128 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0323 | 0.2143 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0158 | 0.0973 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.1433 | 1 | 1 |
Loa Loa (eye worm) | endoplasmin | 0.0028 | 0.0056 | 0.0056 |
Brugia malayi | CXXC zinc finger family protein | 0.0089 | 0.0488 | 0.0488 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.0244 | 0.0244 |
Brugia malayi | heat shock protein 90 | 0.0028 | 0.0056 | 0.0056 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.1433 | 1 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.1433 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0038 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0048 | 0.0197 | 0.0197 |
Leishmania major | heat shock protein 83-1 | 0.0028 | 0.0056 | 0.0297 |
Brugia malayi | Latrophilin receptor protein 2 | 0.005 | 0.0211 | 0.0211 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -6.453 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.599 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.57 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.337 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.232 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.194 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.157 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.063 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.994 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.788 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the K-562 Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.335 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.109 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.