Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | serotonin receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Trypanosoma brucei | cytochrome P450, putative | 0.0024 | 0.2268 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0592 | 0.0592 |
Schistosoma mansoni | myosin xvIII | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0015 | 0.0592 | 0.5 |
Brugia malayi | G-protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Cytochrome P450 family protein | 0.0015 | 0.0592 | 0.0592 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 1 | 1 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | sulfakinin receptor protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Dopamine receptor protein 2 | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | allatostatin A receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Cytochrome P450 family protein | 0.0024 | 0.2268 | 0.2268 |
Brugia malayi | follicle stimulating hormone receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0015 | 0.0592 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | fmrfamide receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.004 | 0.5185 | 0.5185 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0015 | 0.0592 | 0.5 |
Schistosoma mansoni | histamine h1 receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | neuropeptide receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | neuropeptide receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0015 | 0.0592 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0015 | 0.0592 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | G-protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Cytochrome P450 family protein | 0.0056 | 0.7891 | 0.7891 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0038 | 0.4705 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0015 | 0.0592 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0015 | 0.0592 | 0.5 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0035 | 0.4233 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0015 | 0.0592 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0015 | 0.0592 | 0.0592 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | GnHR receptor homolog | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0015 | 0.0592 | 0.5 |
Echinococcus granulosus | sex peptide receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0015 | 0.0592 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0015 | 0.0592 | 0.5 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | biogenic amine receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | g protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | cytochrome P450 | 0.0015 | 0.0592 | 0.0592 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0035 | 0.4233 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | neuropeptide s receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | 0.0015 | 0.0592 | 0.0592 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | RE15519p | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | G protein-coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Serotonin receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0015 | 0.0592 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 1 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.004 | 0.5185 | 0.5185 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | somatostatin receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | allatostatin A receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0015 | 0.0592 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0035 | 0.4233 | 0.4233 |
Leishmania major | cytochrome p450-like protein | 0.0024 | 0.2268 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0044 | 0.5856 | 0.5856 |
Brugia malayi | Serotonin receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | neuropeptide receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | larval opioid receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 1 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | cytochrome P450 | 0.0015 | 0.0592 | 0.0592 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | opsin-like receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4221 | 0.4221 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0035 | 0.4233 | 0.4233 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0024 | 0.2268 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | serotonin receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Melatonin receptor type 1A | 0.0035 | 0.4233 | 0.4233 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0024 | 0.2268 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | g protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | neuropeptide receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0015 | 0.0592 | 0.5 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | orexin receptor type 2 | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0024 | 0.2268 | 1 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0035 | 0.4233 | 0.4233 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0038 | 0.4705 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | sex peptide receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | neuropeptide receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Dopamine receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0044 | 0.5856 | 0.5856 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Dopamine receptor protein 1 | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | opsin-like receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | neuropeptide receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0015 | 0.0592 | 0.5 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | neuropeptide receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0015 | 0.0592 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0015 | 0.0592 | 0.5 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Echinococcus granulosus | serotonin receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0024 | 0.2268 | 0.2268 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | neuropeptide F receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0015 | 0.0592 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.004 | 0.5185 | 0.5185 |
Brugia malayi | neuropeptide F receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.004 | 0.5185 | 0.5185 |
Mycobacterium leprae | putative cytochrome p450 | 0.0015 | 0.0592 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | somatostatin receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Echinococcus multilocularis | fmrfamide receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0015 | 0.0592 | 0.5 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Brugia malayi | cytochrome P450 | 0.0015 | 0.0592 | 0.0592 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0024 | 0.2268 | 0.2268 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | putative neuropeptide receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | ORL1-like opioid receptor | 0.0035 | 0.4233 | 0.4233 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0015 | 0.0592 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0056 | 0.7891 | 0.7891 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0035 | 0.4233 | 0.4233 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0015 | 0.0592 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0024 | 0.2268 | 0.2268 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0015 | 0.0592 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | fmrfamide receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | biogenic amine receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus granulosus | neuropeptide receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0035 | 0.4233 | 0.4233 |
Onchocerca volvulus | 0.0035 | 0.4233 | 0.5 | |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0035 | 0.4233 | 0.4233 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | TAR-binding protein | 0.0067 | 1 | 1 |
Brugia malayi | AKH receptor | 0.0035 | 0.4233 | 0.4233 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0035 | 0.4233 | 0.4233 |
Brugia malayi | Cytochrome P450 family protein | 0.0024 | 0.2268 | 0.2268 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | biogenic amine receptor | 0.0035 | 0.4233 | 0.4233 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0035 | 0.4233 | 0.4233 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED10 (functional) | > 100 ug kg-1 | Dose producing 10% decrease in heart rate of anesthetized spontaneously hypertensive rats (SHR's) | ChEMBL. | 1495019 |
ED30 (functional) | > 100 ug kg-1 | Dose producing 30% decrease in blood pressure of anesthetized spontaneously hypertensive rats (SHR's) | ChEMBL. | 1495019 |
Ki (binding) | > 181 nM | Binding affinity against adenosine A2 receptor from rat striatum using [3H]-NECA as radioligand. | ChEMBL. | 1495019 |
Ki (binding) | > 472 nM | Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]-cyclohexyladenosine as radioligand. | ChEMBL. | 1495019 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.