Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | amine GPCR | 0.0064 | 0.5352 | 1 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0024 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0064 | 0.5352 | 1 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0024 | 0 | 0.5 |
Mycobacterium leprae | putative cytochrome p450 | 0.0024 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0024 | 0 | 0.5 |
Brugia malayi | follicle stimulating hormone receptor | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0064 | 0.5352 | 1 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | neuropeptide F receptor | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | allatostatin A receptor | 0.0064 | 0.5352 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | neuropeptide receptor | 0.0064 | 0.5352 | 1 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0064 | 0.5352 | 1 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0064 | 0.5352 | 1 |
Brugia malayi | GnHR receptor homolog | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0098 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0024 | 0 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0064 | 0.5352 | 1 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0024 | 0 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0049 | 0.3402 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0064 | 0.5352 | 1 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Echinococcus multilocularis | serotonin receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0064 | 0.5352 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0032 | 0.1124 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0024 | 0 | 0.5 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0064 | 0.5352 | 1 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Brugia malayi | neuropeptide F receptor | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0064 | 0.5352 | 1 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | sulfakinin receptor protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | neuropeptide receptor | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0024 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0038 | 0.1859 | 0.3473 |
Schistosoma mansoni | opsin-like receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | putative neuropeptide receptor | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | biogenic amine receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | fmrfamide receptor | 0.0064 | 0.5352 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0049 | 0.3402 | 0.3402 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0035 | 0.1431 | 0.1431 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0064 | 0.5352 | 1 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | amine GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0064 | 0.5352 | 1 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0815 | 0.0815 |
Echinococcus multilocularis | somatostatin receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0038 | 0.1859 | 0.3473 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | Serotonin receptor | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0049 | 0.3402 | 0.3402 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | serotonin receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | amine GPCR | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | neuropeptide s receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0173 | 0.0173 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0049 | 0.3402 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0035 | 0.1431 | 0.2673 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0049 | 0.3402 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.5352 | 1 |
Brugia malayi | Dopamine receptor | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0064 | 0.5352 | 1 |
Brugia malayi | AKH receptor | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0064 | 0.5352 | 1 |
Brugia malayi | G protein-coupled receptor | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0064 | 0.5352 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0064 | 0.5352 | 0.5 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0064 | 0.5352 | 0.5352 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0024 | 0 | 0.5 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | amine GPCR | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0024 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0024 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0024 | 0 | 0.5 |
Echinococcus granulosus | serotonin receptor | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0024 | 0 | 0.5 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0064 | 0.5352 | 1 |
Brugia malayi | larval opioid receptor | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | Serotonin receptor | 0.0064 | 0.5352 | 0.5352 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0064 | 0.5352 | 0.5 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0024 | 0 | 0.5 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0024 | 0 | 0.5 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0024 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0049 | 0.3402 | 0.3402 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0064 | 0.5352 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0032 | 0.1124 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0049 | 0.3402 | 0.3402 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0035 | 0.1431 | 0.1431 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Brugia malayi | RE15519p | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0064 | 0.5352 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | G-protein coupled receptor | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | G-protein coupled receptor | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | amine GPCR | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0024 | 0 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0024 | 0 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0064 | 0.5352 | 0.5352 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Echinococcus multilocularis | orexin receptor type 2 | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | Cytochrome P450 family protein | 0.0049 | 0.3402 | 0.3402 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0064 | 0.5352 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0064 | 0.5352 | 0.5352 |
Leishmania major | cytochrome p450-like protein | 0.0049 | 0.3402 | 1 |
Onchocerca volvulus | 0.0064 | 0.5352 | 0.5 | |
Echinococcus multilocularis | sex peptide receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | Dopamine receptor protein 2 | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | g protein coupled receptor | 0.0064 | 0.5352 | 1 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0064 | 0.5352 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0049 | 0.3402 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0064 | 0.5352 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | g protein coupled receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | biogenic amine receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0035 | 0.1431 | 0.2673 |
Echinococcus granulosus | g protein coupled receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | biogenic amine receptor | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0024 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0024 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0064 | 0.5352 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0024 | 0 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | myosin xvIII | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | orexin receptor type 2 | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0024 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Brugia malayi | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0064 | 0.5352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5352 | 0.5352 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0064 | 0.5352 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0064 | 0.5352 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.0064 | 0.5352 | 1 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0064 | 0.5352 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.