Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.022 | 0.0517 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0072 | 0.0495 | 0.1164 |
Trypanosoma brucei | heat shock protein, putative | 0.003 | 0.0091 | 0.0587 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0028 | 0.0078 | 0.0078 |
Echinococcus multilocularis | heat shock protein | 0.003 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0093 | 0.0698 | 0.164 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0031 | 0.0106 | 0.0106 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0057 | 0.0356 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0521 | 0.1224 |
Trichomonas vaginalis | helicase, putative | 0.0021 | 0.0012 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0128 | 0.03 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0184 | 0.1558 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0064 | 0.0421 | 0.3051 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.1073 | 1 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.003 | 0.0091 | 0.0587 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0338 | 0.302 | 0.7106 |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.0388 | 0.2487 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0057 | 0.0356 | 0.0356 |
Echinococcus multilocularis | tar DNA binding protein | 0.034 | 0.3039 | 0.3039 |
Brugia malayi | beta-NAC-like protein | 0.0184 | 0.1558 | 0.3661 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0184 | 0.1558 | 0.3666 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0196 | 0.0461 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0032 | 0.012 | 0.0769 |
Trypanosoma brucei | heat shock protein, putative | 0.003 | 0.0091 | 0.0587 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0028 | 0.0078 | 0.0182 |
Brugia malayi | Bromodomain containing protein | 0.0085 | 0.0614 | 0.1444 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0028 | 0.0078 | 0.0078 |
Schistosoma mansoni | hypothetical protein | 0.031 | 0.2759 | 0.2759 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0018 | 0.0018 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0519 | 0.0519 |
Schistosoma mansoni | cpg binding protein | 0.0101 | 0.0768 | 0.0768 |
Brugia malayi | RNA binding protein | 0.034 | 0.3039 | 0.714 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0028 | 0.0078 | 0.0182 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0028 | 0.0078 | 0.0182 |
Schistosoma mansoni | thyroid hormone receptor | 0.0028 | 0.0078 | 0.0078 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.012 | 0.012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.027 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0495 | 0.1164 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0031 | 0.0106 | 0.0106 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0025 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0028 | 0.0078 | 0.0182 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0128 | 0.0128 |
Brugia malayi | Isocitrate dehydrogenase | 0.0032 | 0.012 | 0.0282 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0033 | 0.0122 | 0.0286 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.027 | 0.027 |
Loa Loa (eye worm) | histone methyltransferase | 0.0031 | 0.0106 | 0.0249 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0023 | 0.0034 | 0.0221 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0028 | 0.0078 | 0.0182 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0021 | 0.0012 | 0.0029 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0028 | 0.0078 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0356 | 0.0837 |
Brugia malayi | hypothetical protein | 0.0468 | 0.4256 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0028 | 0.0078 | 0.0182 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.027 | 0.0635 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0021 | 0.0012 | 0.0029 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0338 | 0.302 | 0.7106 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Plasmodium falciparum | heat shock protein 90 | 0.003 | 0.0091 | 0.0587 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0057 | 0.0356 | 0.0356 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.003 | 0.0091 | 0.0587 |
Loa Loa (eye worm) | TAR-binding protein | 0.034 | 0.3039 | 0.714 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0627 | 0.5761 | 0.5761 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0128 | 0.03 |
Echinococcus multilocularis | heat shock protein 90 | 0.0023 | 0.0034 | 0.0034 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0032 | 0.012 | 0.0769 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.003 | 0.0091 | 0.0587 |
Brugia malayi | ecdysteroid receptor | 0.0028 | 0.0078 | 0.0182 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0812 | 0.1907 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0061 | 0.0388 | 0.2487 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0068 | 0.0461 | 0.0461 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.0388 | 0.0388 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0021 | 0.0012 | 0.0029 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0203 | 0.1736 | 0.1736 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.185 | 0.4346 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0028 | 0.0078 | 0.0078 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0338 | 0.302 | 0.7106 |
Trypanosoma brucei | heat shock protein, putative | 0.003 | 0.0091 | 0.0587 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0032 | 0.012 | 0.0869 |
Brugia malayi | CXXC zinc finger family protein | 0.0093 | 0.0698 | 0.164 |
Trichomonas vaginalis | set domain proteins, putative | 0.0467 | 0.425 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0028 | 0.0078 | 0.0182 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0338 | 0.302 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0079 | 0.0559 | 0.0559 |
Echinococcus multilocularis | heat shock protein 90 | 0.003 | 0.0091 | 0.0091 |
Schistosoma mansoni | thyroid hormone receptor | 0.0028 | 0.0078 | 0.0078 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0028 | 0.0078 | 0.0078 |
Echinococcus granulosus | heat shock protein | 0.003 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0078 | 0.0182 |
Onchocerca volvulus | 0.0061 | 0.0388 | 0.0742 | |
Onchocerca volvulus | 0.0467 | 0.425 | 0.9985 | |
Trypanosoma brucei | heat shock protein, putative | 0.003 | 0.0091 | 0.0587 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.0196 | 0.046 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0021 | 0.0012 | 0.0029 |
Onchocerca volvulus | 0.0093 | 0.0698 | 0.1485 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0519 | 0.0519 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.02 | 0.1712 | 0.1712 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0128 | 0.0128 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0025 | 0.0052 | 0.0052 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0028 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0078 | 0.0182 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.012 | 0.012 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0128 | 0.03 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0023 | 0.0034 | 0.0034 |
Brugia malayi | isocitrate dehydrogenase | 0.0032 | 0.012 | 0.0282 |
Trichomonas vaginalis | heat shock protein, putative | 0.0023 | 0.0034 | 0.0081 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.027 | 0.027 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0028 | 0.0078 | 0.0078 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0028 | 0.0078 | 0.0078 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0032 | 0.012 | 0.012 |
Brugia malayi | nuclear receptor NHR-88 | 0.0028 | 0.0078 | 0.0182 |
Brugia malayi | PHD-finger family protein | 0.0032 | 0.0112 | 0.0263 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0032 | 0.012 | 0.0769 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0421 | 0.0421 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0029 | 0.0088 | 0.0088 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0064 | 0.0421 | 0.0421 |
Echinococcus granulosus | endoplasmin | 0.0023 | 0.0034 | 0.0034 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0032 | 0.012 | 0.0769 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0078 | 0.0182 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.4256 | 1 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.005 | 0.029 | 0.029 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0057 | 0.0356 | 0.0356 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.003 | 0.0091 | 0.0303 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0519 | 0.0519 |
Schistosoma mansoni | transcription factor btf3 | 0.0184 | 0.1558 | 0.1558 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0028 | 0.0078 | 0.0182 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0184 | 0.1558 | 1 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0023 | 0.0034 | 0.0221 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0032 | 0.012 | 0.012 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0028 | 0.0078 | 0.0078 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0184 | 0.1558 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0025 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0028 | 0.0078 | 0.0182 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0227 | 0.0227 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.005 | 0.029 | 0.029 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.1073 | 1 | 1 |
Schistosoma mansoni | alkaline phosphatase | 0.1073 | 1 | 1 |
Entamoeba histolytica | heat shock protein 90, putative | 0.003 | 0.0091 | 0.0303 |
Giardia lamblia | Grp94/Hsp90 | 0.0023 | 0.0034 | 0.0114 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Schistosoma mansoni | cpg binding protein | 0.0093 | 0.0698 | 0.0698 |
Plasmodium vivax | endoplasmin, putative | 0.003 | 0.0091 | 0.0587 |
Schistosoma mansoni | zinc finger protein | 0.0026 | 0.0058 | 0.0058 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0519 | 0.1717 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0023 | 0.0034 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0064 | 0.0421 | 0.2699 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0032 | 0.012 | 0.0769 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.003 | 0.0091 | 0.0587 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0128 | 0.0128 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.027 | 0.027 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0338 | 0.302 | 0.7106 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0023 | 0.0023 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0061 | 0.0388 | 0.0388 |
Echinococcus multilocularis | cpg binding protein | 0.0101 | 0.0768 | 0.0768 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0056 | 0.0348 | 0.0348 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.005 | 0.029 | 0.029 |
Trypanosoma brucei | heat shock protein 90, putative | 0.003 | 0.0091 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.029 | 0.0681 |
Trypanosoma brucei | heat shock protein, putative | 0.003 | 0.0091 | 0.0587 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0025 | 0.0052 | 0.0052 |
Onchocerca volvulus | 0.0044 | 0.0227 | 0.0358 | |
Brugia malayi | Pre-SET motif family protein | 0.0411 | 0.3714 | 0.8725 |
Schistosoma mansoni | hypothetical protein | 0.0488 | 0.4444 | 0.4444 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0184 | 0.1558 | 0.3666 |
Brugia malayi | hypothetical protein | 0.0215 | 0.185 | 0.4346 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0172 | 0.0172 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0184 | 0.1558 | 0.5159 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0128 | 0.0128 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.029 | 0.0681 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0203 | 0.1736 | 0.1736 |
Loa Loa (eye worm) | RNA binding protein | 0.034 | 0.3039 | 0.714 |
Trichomonas vaginalis | heat shock protein, putative | 0.003 | 0.0091 | 0.0215 |
Trypanosoma brucei | heat shock protein, putative | 0.003 | 0.0091 | 0.0587 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0057 | 0.0356 | 0.0837 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0021 | 0.0012 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0495 | 0.0495 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0421 | 0.3051 |
Schistosoma mansoni | tar DNA-binding protein | 0.034 | 0.3039 | 0.3039 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0029 | 0.0088 | 0.0088 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0028 | 0.0078 | 0.0182 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0215 | 0.185 | 0.185 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.003 | 0.0091 | 0.0587 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0018 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0078 | 0.0182 |
Loa Loa (eye worm) | mbt repeat family protein | 0.005 | 0.029 | 0.0681 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0338 | 0.302 | 1 |
Plasmodium vivax | heat shock protein 86, putative | 0.003 | 0.0091 | 0.0587 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0028 | 0.0078 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0559 | 0.1313 |
Trichomonas vaginalis | heat shock protein, putative | 0.0023 | 0.0034 | 0.0081 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0079 | 0.0559 | 0.0559 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0028 | 0.0078 | 0.0078 |
Schistosoma mansoni | cpg binding protein | 0.0101 | 0.0768 | 0.0768 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0105 | 0.0812 | 0.1907 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0519 | 0.1717 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0029 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.029 | 0.0681 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0165 | 0.1379 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0023 | 0.0034 | 0.0081 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.003 | 0.0091 | 0.0587 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0028 | 0.0078 | 0.0182 |
Schistosoma mansoni | hypothetical protein | 0.0488 | 0.4444 | 0.4444 |
Schistosoma mansoni | heat shock protein | 0.003 | 0.0091 | 0.0091 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.027 | 0.027 |
Echinococcus multilocularis | geminin | 0.0488 | 0.4444 | 0.4444 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0105 | 0.0812 | 0.1907 |
Loa Loa (eye worm) | heat shock protein 90 | 0.003 | 0.0091 | 0.0215 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0338 | 0.302 | 0.7106 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0028 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | MBCTL1 | 0.0057 | 0.0356 | 0.0837 |
Brugia malayi | heat shock protein 90 | 0.003 | 0.0091 | 0.0215 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0519 | 0.1717 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.027 | 0.027 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0028 | 0.0078 | 0.0182 |
Echinococcus multilocularis | Protein lozenge | 0.0059 | 0.0369 | 0.0369 |
Schistosoma mansoni | lozenge | 0.0059 | 0.0369 | 0.0369 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0028 | 0.0078 | 0.0078 |
Trypanosoma brucei | heat shock protein, putative | 0.003 | 0.0091 | 0.0587 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0028 | 0.0078 | 0.0182 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.1073 | 1 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0064 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.027 | 0.0635 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0028 | 0.0078 | 0.0182 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0215 | 0.185 | 0.185 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0028 | 0.0078 | 0.0182 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0032 | 0.012 | 0.0769 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0028 | 0.0078 | 0.0078 |
Echinococcus granulosus | tar DNA binding protein | 0.034 | 0.3039 | 0.3039 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0028 | 0.0078 | 0.0182 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.005 | 0.029 | 0.0508 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0128 | 0.0128 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0421 | 0.3051 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.029 | 0.029 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0028 | 0.0078 | 0.0078 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0028 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0078 | 0.0182 |
Schistosoma mansoni | tar DNA-binding protein | 0.034 | 0.3039 | 0.3039 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0057 | 0.0356 | 0.0356 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0028 | 0.0078 | 0.0182 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0078 | 0.0182 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0128 | 0.0128 |
Brugia malayi | Endoplasmin precursor | 0.003 | 0.0091 | 0.0215 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.029 | 0.0681 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0028 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | runx1 | 0.0059 | 0.0369 | 0.0867 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0023 | 0.0034 | 0.0221 |
Schistosoma mansoni | nuclear hormone receptor | 0.0028 | 0.0078 | 0.0078 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0028 | 0.0078 | 0.0078 |
Schistosoma mansoni | tar DNA-binding protein | 0.034 | 0.3039 | 0.3039 |
Treponema pallidum | heat shock protein 90 | 0.0023 | 0.0034 | 0.0114 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0064 | 0.0421 | 0.2699 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0079 | 0.0559 | 0.0559 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0338 | 0.302 | 0.7106 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Schistosoma mansoni | survival motor neuron protein | 0.0044 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0028 | 0.0078 | 0.0182 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0182 | 0.1535 | 0.9853 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0023 | 0.0034 | 0.025 |
Leishmania major | basic transcription factor 3a, putative | 0.0184 | 0.1558 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0028 | 0.0078 | 0.0182 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0028 | 0.0078 | 0.0078 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0044 | 0.0227 | 0.0534 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0128 | 0.0128 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0128 | 0.0128 |
Schistosoma mansoni | alkaline phosphatase | 0.1073 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0421 | 0.0421 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.012 | 0.012 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0338 | 0.302 | 0.7106 |
Toxoplasma gondii | NAC domain-containing protein | 0.0184 | 0.1558 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1221 | 0.2869 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0028 | 0.0078 | 0.0182 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0023 | 0.0034 | 0.025 |
Echinococcus multilocularis | endoplasmin | 0.0023 | 0.0034 | 0.0034 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0021 | 0.0012 | 0.0029 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0519 | 0.1717 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0165 | 0.1379 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0032 | 0.012 | 0.0282 |
Echinococcus granulosus | heat shock protein 90 | 0.003 | 0.0091 | 0.0091 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0519 | 0.0519 |
Onchocerca volvulus | 0.005 | 0.029 | 0.0508 | |
Loa Loa (eye worm) | endoplasmin | 0.003 | 0.0091 | 0.0215 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0184 | 0.1558 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.034 | 0.3039 | 0.714 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.029 | 0.029 |
Onchocerca volvulus | 0.0468 | 0.4256 | 1 | |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.0388 | 0.0911 |
Schistosoma mansoni | endoplasmin | 0.003 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.4256 | 1 |
Brugia malayi | TAR-binding protein | 0.034 | 0.3039 | 0.714 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0021 | 0.0012 | 0.0029 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0028 | 0.0078 | 0.0078 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0028 | 0.0078 | 0.0078 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.003 | 0.0091 | 0.0587 |
Echinococcus granulosus | heat shock protein 90 | 0.0023 | 0.0034 | 0.0034 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0025 | 0.0052 | 0.0052 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0079 | 0.0559 | 0.0559 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0184 | 0.1558 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0862 | 0.8002 | 0.8002 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.005 | 0.029 | 0.029 |
Brugia malayi | nuclear hormone receptor | 0.0028 | 0.0078 | 0.0182 |
Trypanosoma brucei | heat shock protein 90, putative | 0.003 | 0.0091 | 0.0587 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0128 | 0.0128 |
Echinococcus granulosus | cpg binding protein | 0.0101 | 0.0768 | 0.0768 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0165 | 0.1379 | 1 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.1073 | 1 | 1 |
Toxoplasma gondii | heat shock protein 90, putative | 0.003 | 0.0091 | 0.0587 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0028 | 0.0078 | 0.0078 |
Echinococcus granulosus | alkaline phosphatase | 0.1073 | 1 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0128 | 0.03 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0032 | 0.012 | 0.0769 |
Echinococcus granulosus | zinc finger protein | 0.0026 | 0.0058 | 0.0058 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Entamoeba histolytica | hypothetical protein | 0.0184 | 0.1558 | 0.5159 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0519 | 0.1219 |
Echinococcus granulosus | geminin | 0.0488 | 0.4444 | 0.4444 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0028 | 0.0078 | 0.0078 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0388 | 0.0388 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0172 | 0.0172 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0023 | 0.0034 | 0.0114 |
Brugia malayi | steroid hormone receptor | 0.0028 | 0.0078 | 0.0182 |
Echinococcus multilocularis | zinc finger protein | 0.0026 | 0.0058 | 0.0058 |
Schistosoma mansoni | coup transcription factor | 0.0028 | 0.0078 | 0.0078 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0028 | 0.0078 | 0.0078 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.012 | 0.012 |
Echinococcus multilocularis | transcription factor btf3 | 0.0184 | 0.1558 | 0.1558 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.027 | 0.027 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0338 | 0.302 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.005 | 0.029 | 0.029 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0032 | 0.012 | 0.012 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0032 | 0.012 | 0.0769 |
Schistosoma mansoni | endoplasmin | 0.003 | 0.0091 | 0.0091 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0627 | 0.5761 | 0.5761 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0078 | 0.0182 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0032 | 0.012 | 0.0769 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0028 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | ICD-1 protein | 0.0184 | 0.1558 | 0.3661 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0028 | 0.0078 | 0.0182 |
Leishmania major | heat shock protein 83-1 | 0.003 | 0.0091 | 0.0587 |
Echinococcus granulosus | FTZ F1 alpha | 0.0028 | 0.0078 | 0.0078 |
Schistosoma mansoni | tar DNA-binding protein | 0.034 | 0.3039 | 0.3039 |
Schistosoma mansoni | tar DNA-binding protein | 0.034 | 0.3039 | 0.3039 |
Schistosoma mansoni | bromodomain containing protein | 0.0072 | 0.0497 | 0.0497 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0338 | 0.302 | 0.7106 |
Toxoplasma gondii | heat shock protein HSP90 | 0.003 | 0.0091 | 0.0587 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0184 | 0.1558 | 0.3666 |
Brugia malayi | Probable ATP-dependent helicase DHX35 | 0.0148 | 0.1221 | 0.2869 |
Echinococcus granulosus | dnaJ subfamily B | 0.0862 | 0.8002 | 0.8002 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0411 | 0.3714 | 0.8725 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0105 | 0.0812 | 0.1907 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.1073 | 1 | 1 |
Schistosoma mansoni | heat shock protein | 0.003 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | DEAH box polypeptide 35 | 0.0148 | 0.1221 | 0.2869 |
Echinococcus granulosus | transcription factor btf3 | 0.0184 | 0.1558 | 0.1558 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0421 | 0.3051 |
Schistosoma mansoni | hypothetical protein | 0.0557 | 0.5105 | 0.5105 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0012 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0862 | 0.8002 | 0.8002 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0078 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0078 | 0.0182 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0627 | 0.5761 | 0.5761 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0028 | 0.0078 | 0.0078 |
Entamoeba histolytica | heat shock protein 90, putative | 0.003 | 0.0091 | 0.0303 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0021 | 0.0012 | 0.0029 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0028 | 0.0078 | 0.0078 |
Echinococcus multilocularis | alkaline phosphatase | 0.1073 | 1 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0338 | 0.302 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0028 | 0.0078 | 0.0078 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0068 | 0.0461 | 0.0461 |
Brugia malayi | RNA recognition motif domain containing protein | 0.034 | 0.3039 | 0.714 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -5.802 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.802 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.801 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.798 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.774 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.762 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.736 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.734 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.724 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.7 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.