Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.152 | 0.3902 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0218 | 0.0559 |
Brugia malayi | Bromodomain containing protein | 0.0074 | 0.421 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.3349 | 0.3255 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.3086 | 0.2988 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0041 | 0.1752 | 0.3319 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.3086 | 0.2988 |
Echinococcus multilocularis | geminin | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1834 | 0.4709 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.1515 | 0.2673 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0041 | 0.1752 | 0.1635 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0358 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.3896 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1694 | 0.4348 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0041 | 0.1752 | 0.1635 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.1341 | 0.1218 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0041 | 0.1752 | 0.1635 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.1341 | 0.1218 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0041 | 0.1752 | 0.4498 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0218 | 0.0079 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0041 | 0.1752 | 0.1635 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0041 | 0.1752 | 0.1635 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0358 | 0.0221 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0358 | 0.0221 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0041 | 0.1752 | 0.1635 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0041 | 0.1752 | 0.1635 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.