Detailed information for compound 1612694

Basic information

Technical information
  • TDR Targets ID: 1612694
  • Name: NSC135035
  • MW: 539.574 | Formula: C29H33NO9
  • H donors: 3 H acceptors: 3 LogP: 2.32 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc(cc1O)/C=C/C(=O)OC1CC23CCNC43C(C1OC)(OC)OC(c1c2c(O)c(cc1)OC)C4
  • InChi: 1S/C29H33NO9/c1-34-19-8-5-16(13-18(19)31)6-10-23(32)38-22-14-27-11-12-30-28(27)15-21(39-29(28,37-4)26(22)36-3)17-7-9-20(35-2)25(33)24(17)27/h5-10,13,21-22,26,30-31,33H,11-12,14-15H2,1-4H3/b10-6+
  • InChiKey: YYOXLLHHBARIFS-UXBLZVDNSA-N  


Substructure search Similarity search

Network

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Synonyms

  • STEPHISOFERULINE

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0048 0.0041 0.0083
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0122
Brugia malayi PHD-finger family protein 0.0085 0.0094 0.0191
Brugia malayi nuclear hormone receptor 0.0086 0.0095 0.0193
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0086 0.0095 0.0193
Schistosoma mansoni hypothetical protein 0.0289 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.0026
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0038 0.1385
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0027 0.0096
Schistosoma mansoni alpha-glucosidase 0.0292 0.0388 0.0388
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0115 0.0137 0.0219
Loa Loa (eye worm) hypothetical protein 0.0529 0.0727 0.1476
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0103 0.0265
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0046 0.0038 0.0076
Toxoplasma gondii PHD-finger domain-containing protein 0.0078 0.0084 0.0134
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0073 0.1611
Giardia lamblia Kinase, PLK 0.029 0.0386 0.0618
Loa Loa (eye worm) steroid hormone receptor 0.0086 0.0095 0.0193
Brugia malayi conserved hypotetical protein 0.0041 0.003 0.0061
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0105 0.0123 0.0122
Plasmodium falciparum ataxin-2 like protein, putative 0.0644 0.0891 0.1427
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.029 0.0386 0.1745
Echinococcus granulosus Protein patched homolog 1 0.0082 0.009 0.009
Schistosoma mansoni survival motor neuron protein 0.0253 0.0333 0.0333
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0041 0.0904
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0041 0.0896
Brugia malayi Flap endonuclease-1 0.0053 0.0048 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0031 0.014
Echinococcus multilocularis dna polymerase eta 0.006 0.0058 0.0057
Echinococcus multilocularis cysteine protease 0.0105 0.0123 0.0122
Mycobacterium tuberculosis Probable thioesterase TesA 0.0021 0.0002 0.0002
Schistosoma mansoni cathepsin s 0.0035 0.0022 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0086 0.0095 0.0193
Loa Loa (eye worm) bromodomain containing protein 0.0034 0.0021 0.0042
Brugia malayi nuclear hormone receptor 0.0041 0.003 0.0061
Trypanosoma cruzi cysteine peptidase, putative 0.0202 0.0261 0.1177
Onchocerca volvulus 0.0041 0.003 0.011
Echinococcus granulosus PHD finger protein rhinoceros 0.0239 0.0314 0.0314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0032 0.0082
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0046 0.0038 0.0037
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0003 0.0015
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0078 0.0084 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.01 0.0257
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Echinococcus multilocularis beta LACTamase domain containing family member 0.0259 0.0341 0.0341
Echinococcus granulosus chromobox protein 1 0.0068 0.0069 0.0069
Echinococcus granulosus thyroid hormone receptor alpha 0.0041 0.003 0.003
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0046 0.0038 0.0076
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0003 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0031 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0041 0.0185
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0038 0.017
Leishmania major DNA polymerase eta, putative 0.006 0.0058 0.0259
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0115 0.0137 0.0137
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0006 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0096 0.0247
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Echinococcus granulosus sodium:myo inositol cotransporter 0.0039 0.0028 0.0028
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.0083 0.0168
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0095 0.0193
Schistosoma mansoni smad 0.0106 0.0123 0.0123
Schistosoma mansoni jumonji/arid domain-containing protein 0.0297 0.0395 0.0395
Loa Loa (eye worm) pigment dispersing factor receptor c 0.2058 0.2907 0.5907
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0009
Toxoplasma gondii ABC1 family protein 0.0259 0.0341 0.0546
Loa Loa (eye worm) hypothetical protein 0.0039 0.0028 0.0058
Leishmania major alpha glucosidase II subunit, putative 0.0075 0.008 0.036
Loa Loa (eye worm) glutathione reductase 0.0132 0.0161 0.0327
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Schistosoma mansoni hypothetical protein 0.0078 0.0084 0.0084
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0041 0.003 0.003
Echinococcus granulosus dna polymerase eta 0.006 0.0058 0.0057
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0077 0.0083 0.0373
Giardia lamblia Histone acetyltransferase GCN5 0.0161 0.0202 0.0323
Brugia malayi Calcitonin receptor-like protein seb-1 0.2058 0.2907 0.5907
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0023 0.0006 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.0115 0.0137 0.0353
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0006 0.0025
Brugia malayi jmjC domain containing protein 0.0297 0.0395 0.0803
Onchocerca volvulus 0.0028 0.0013 0.0046
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0302 0.0402 0.1723
Onchocerca volvulus 0.0026 0.001 0.0034
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0049 0.0042 0.0042
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0086 0.0095 0.0095
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0046 0.0038 0.0097
Echinococcus multilocularis jumonji domain containing 1A 0.0077 0.0083 0.0082
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0042 0.0085
Entamoeba histolytica hypothetical protein 0.0042 0.0032 0.0703
Loa Loa (eye worm) hypothetical protein 0.0077 0.0083 0.0168
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0086 0.0095 0.0095
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0012 0.0055
Entamoeba histolytica serine/threonine protein kinase, putative 0.029 0.0386 0.8537
Schistosoma mansoni intermediate filament proteins 0.0028 0.0013 0.0013
Echinococcus granulosus lysine specific demethylase 5A 0.0297 0.0395 0.0395
Schistosoma mansoni thyroid hormone receptor 0.0751 0.1043 0.1043
Brugia malayi hypothetical protein 0.0041 0.003 0.0061
Echinococcus multilocularis ecdysone induced protein 78C 0.0086 0.0095 0.0095
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0335 0.045 0.1929
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0247 0.0324 0.0519
Trypanosoma cruzi target of rapamycin kinase 3 0.0091 0.0103 0.0464
Trichomonas vaginalis ap endonuclease, putative 0.0115 0.0137 0.0353
Brugia malayi Latrophilin receptor protein 2 0.0651 0.0901 0.183
Giardia lamblia NADH oxidase lateral transfer candidate 0.0046 0.0038 0.006
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0023 0.0006 0.0006
Trypanosoma cruzi cruzipain precursor, putative 0.0202 0.0261 0.1177
Echinococcus granulosus lysine specific demethylase 6a 0.0077 0.0083 0.0082
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0023 0.0006 0.0015
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0026 0.001 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0073 0.0188
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0042 0.0032 0.0032
Schistosoma mansoni z-protein (S1r protein) 0.0026 0.001 0.0009
Brugia malayi hypothetical protein 0.0416 0.0565 0.1149
Onchocerca volvulus Protein ultraspiracle homolog 0.0086 0.0095 0.0347
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0041 0.0083
Plasmodium vivax SET domain containing protein 0.0028 0.0012 0.002
Schistosoma mansoni cellular tumor antigen P53 0.1024 0.1432 0.1431
Echinococcus multilocularis JmjC domain containing protein 4 0.0077 0.0083 0.0082
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0633 0.0875 0.0875
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.0083 0.0168
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.0083 0.0168
Loa Loa (eye worm) hypothetical protein 0.0101 0.0116 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.013 0.0335
Echinococcus multilocularis lamin dm0 0.0028 0.0013 0.0013
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.008 0.0206
Echinococcus granulosus neuropeptide s receptor 0.0515 0.0707 0.0706
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0076
Loa Loa (eye worm) RNA binding protein 0.0661 0.0915 0.1859
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0041 0.0171
Schistosoma mansoni nocturnin 0.0023 0.0006 0.0006
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0023 0.0006 0.0015
Brugia malayi nuclear receptor NHR-88 0.0086 0.0095 0.0193
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0046 0.0038 0.0076
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0105 0.0123 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0086 0.0095 0.0193
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.0123 0.271
Schistosoma mansoni hypothetical protein 0.0651 0.0901 0.0901
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0006 0.0011
Onchocerca volvulus 0.0258 0.034 0.1238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0066 0.0169
Onchocerca volvulus 0.0086 0.0095 0.0347
Loa Loa (eye worm) DR-78 0.0041 0.003 0.0061
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0013 0.0026
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0046 0.0038 0.0038
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1653 0.2329 1
Mycobacterium tuberculosis Probable hydrolase 0.0259 0.0341 0.1461
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0221 0.0287 0.1298
Plasmodium vivax vivapain-1 0.0054 0.005 0.008
Plasmodium vivax unspecified product 0.0035 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0058 0.0259
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0026 0.001 0.0019
Loa Loa (eye worm) ctsf protein 0.0105 0.0123 0.0249
Onchocerca volvulus Glucosylceramidase homolog 0.0359 0.0484 0.1762
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.0123 0.0316
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0012 0.0055
Trypanosoma cruzi cysteine peptidase, putative 0.0105 0.0123 0.0554
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0027 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0045
Echinococcus granulosus traf and tnf receptor associated protein 0.0023 0.0006 0.0006
Trichomonas vaginalis sucrase-isomaltase, putative 0.0075 0.008 0.0206
Trichomonas vaginalis CAMK family protein kinase 0.029 0.0386 0.0996
Schistosoma mansoni ferritin 0.0035 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0651 0.0901 0.0901
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0041 0.035
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.008 0.0206
Loa Loa (eye worm) PHD-finger family protein 0.0239 0.0314 0.0637
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0031 0.014
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0058 0.0493
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0023 0.0006 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.013 0.0335
Echinococcus multilocularis cysteine protease 0.0105 0.0123 0.0122
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0016 0.0041
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0115 0.0137 0.0219
Brugia malayi nuclear hormone receptor family member odr-7 0.0041 0.003 0.0061
Brugia malayi Cathepsin L-like precursor 0.0071 0.0073 0.0148
Echinococcus granulosus neuropeptide receptor A26 0.0515 0.0707 0.0706
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Schistosoma mansoni Smad4 0.0106 0.0123 0.0123
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0015 0.0065
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0105 0.0123 0.0196
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0041 0.0083
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.003
Schistosoma mansoni chromobox protein 0.0068 0.0069 0.0069
Brugia malayi Bromodomain containing protein 0.0257 0.0338 0.0687
Loa Loa (eye worm) hypothetical protein 0.0059 0.0057 0.0115
Brugia malayi nuclear receptor RXR 0.0046 0.0037 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0016 0.0041
Trypanosoma cruzi PAB1-binding protein , putative 0.0644 0.0891 0.4028
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0046 0.0038 0.0037
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0086 0.0095 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.029 0.0386 0.0996
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0045 0.0982
Plasmodium vivax exodeoxyribonuclease III, putative 0.0023 0.0006 0.0009
Mycobacterium ulcerans bacterioferritin BfrB 0.0035 0.0022 0.0183
Entamoeba histolytica Flap nuclease, putative 0.0053 0.0048 0.1062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0086 0.0095 0.0193
Brugia malayi hypothetical protein 0.0026 0.001 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.029 0.0386 0.0996
Echinococcus granulosus serine protein kinase ATM 0.0042 0.0032 0.0032
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0024 0.0097
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0046 0.0038 0.017
Trichomonas vaginalis D-aminoacylase, putative 0.0259 0.0341 0.0881
Onchocerca volvulus 0.0037 0.0025 0.0092
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0086 0.0095 0.0095
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0046 0.0038 0.0097
Loa Loa (eye worm) hypothetical protein 0.2219 0.3136 0.6373
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.005 0.0101
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0046 0.0038 0.0037
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1571 0.2212 1
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.005 0.0101
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.008 0.0206
Loa Loa (eye worm) hypothetical protein 0.0086 0.0095 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0096 0.0247
Brugia malayi MH1 domain containing protein 0.0236 0.031 0.0629
Loa Loa (eye worm) hypothetical protein 0.0259 0.0341 0.0693
Leishmania major cathepsin L-like protease 0.0202 0.0261 0.1177
Schistosoma mansoni smad1 5 8 and 0.0236 0.031 0.0309
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Brugia malayi nuclear receptor NHR-67 0.0041 0.003 0.0061
Loa Loa (eye worm) hypothetical protein 0.0082 0.009 0.0182
Leishmania major hypothetical protein, conserved 0.0023 0.0006 0.0025
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0049 0.0042 0.0189
Brugia malayi RNA binding protein 0.0661 0.0915 0.1859
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0042 0.0085
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0042 0.0032 0.0144
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0048
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0023 0.0006 0.0009
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0021 0.0002 0.0022
Mycobacterium tuberculosis Probable esterase LipL 0.0259 0.0341 0.1461
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Echinococcus granulosus expressed protein 0.0046 0.0038 0.0037
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0023 0.0006 0.0025
Schistosoma mansoni hypothetical protein 0.0021 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0042 0.0108
Echinococcus granulosus segment polarity protein dishevelled 0.0026 0.001 0.0009
Leishmania major cysteine peptidase A (CPA) 0.0105 0.0123 0.0554
Echinococcus granulosus survival motor neuron protein 1 0.1241 0.1741 0.1741
Leishmania major phosphatidylinositol kinase related protein, putative 0.0024 0.0006 0.0027
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0006 0.0025
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0046 0.0038 0.0037
Onchocerca volvulus 0.0023 0.0006 0.002
Schistosoma mansoni high-affinity choline transporter 0.0356 0.0481 0.048
Schistosoma mansoni GTP-binding protein alpha subunit 0.0046 0.0038 0.0037
Entamoeba histolytica cysteine proteinase 2 0.0054 0.005 0.1099
Loa Loa (eye worm) hypothetical protein 0.0086 0.0095 0.0193
Mycobacterium tuberculosis Probable lipase LipD 0.0259 0.0341 0.1461
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0289 0.0384 0.0384
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0078 0.0084 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0077 0.0198
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0046 0.0037 0.0037
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0259 0.0341 0.0693
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0024 0.0199
Trichomonas vaginalis glucosylceramidase, putative 0.0546 0.0751 0.1939
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1571 0.2212 1
Schistosoma mansoni regulator of G protein signaling 0.0026 0.001 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.008 0.036
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0122
Loa Loa (eye worm) histone methyltransferase 0.0036 0.0023 0.0047
Plasmodium vivax JmjC domain containing protein 0.0077 0.0083 0.0132
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.1063 0.1488 0.1488
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0115 0.0137 0.0583
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0006 0.0122
Schistosoma mansoni hypothetical protein 0.0079 0.0086 0.0085
Onchocerca volvulus 0.0259 0.0341 0.1243
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0086 0.0095 0.0193
Schistosoma mansoni zinc finger protein 0.0041 0.003 0.003
Echinococcus multilocularis musashi 0.0028 0.0013 0.0013
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0041 0.0185
Entamoeba histolytica hypothetical protein 0.0024 0.0007 0.0143
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0021 0.0085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.1063 0.1488 0.1488
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0041 0.003 0.0061
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0006 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0115 0.0137 0.0619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0076 0.0196
Brugia malayi PHD-finger family protein 0.0239 0.0314 0.0637
Trypanosoma cruzi hypothetical protein, conserved 0.0259 0.0341 0.1543
Entamoeba histolytica cysteine proteinase, putative 0.0054 0.005 0.1099
Loa Loa (eye worm) hypothetical protein 0.0239 0.0314 0.0637
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.001 0.0009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0086 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0023 0.0006 0.0009
Schistosoma mansoni hypothetical protein 0.0239 0.0314 0.0314
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0039 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0105 0.0123 0.0249
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Mycobacterium tuberculosis Probable exported protein 0.0023 0.0006 0.0019
Schistosoma mansoni jumonji/arid domain-containing protein 0.0297 0.0395 0.0395
Brugia malayi G-protein alpha subunit 0.0046 0.0038 0.0076
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.001 0.0009
Brugia malayi Cathepsin L-like precursor 0.0105 0.0123 0.0249
Schistosoma mansoni transcription factor LCR-F1 0.0337 0.0452 0.0452
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0115 0.0137 0.0619
Loa Loa (eye worm) hypothetical protein 0.0106 0.0123 0.025
Echinococcus granulosus beta LACTamase domain containing family member 0.0259 0.0341 0.0341
Leishmania major cathepsin L-like protease 0.0202 0.0261 0.1177
Schistosoma mansoni GTP-binding protein alpha subunit 0.0046 0.0038 0.0037
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.011 0.013 0.0586
Mycobacterium ulcerans thioesterase 0.0021 0.0002 0.0009
Echinococcus multilocularis ferritin 0.0035 0.0022 0.0022
Schistosoma mansoni alpha-glucosidase 0.0292 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Toxoplasma gondii exonuclease III APE 0.0115 0.0137 0.0219
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.06 0.0828 0.0827
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0086 0.0095 0.0095
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0086 0.0095 0.0095
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.1681 0.2369 0.3794
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0038 0.017
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0337 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0071 0.0073 0.0148
Schistosoma mansoni hypothetical protein 0.0337 0.0452 0.0452
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.006 0.0058 0.0242
Toxoplasma gondii hypothetical protein 0.0026 0.001 0.0015
Echinococcus granulosus cathepsin l cysteine peptidase 0.0105 0.0123 0.0122
Leishmania major GTP-binding protein, putative 0.0022 0.0003 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.003 0.003
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0046 0.0038 0.006
Trichomonas vaginalis CAMK family protein kinase 0.029 0.0386 0.0996
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0046 0.0038 0.006
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0009
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0046 0.0038 0.006
Mycobacterium leprae conserved hypothetical protein 0.0259 0.0341 0.7577
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0038 0.017
Brugia malayi cathepsin L-like precursor 0.0071 0.0073 0.0148
Echinococcus granulosus GPCR family 2 0.0651 0.0901 0.0901
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0031 0.0111
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0003 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0083 0.0091 0.0146
Loa Loa (eye worm) nuclear factor I 0.0131 0.0159 0.0323
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0191 0.0245 0.0245
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0016 0.0041
Loa Loa (eye worm) thioredoxin reductase 0.0132 0.0161 0.0327
Brugia malayi MH1 domain containing protein 0.0131 0.0159 0.0323
Echinococcus granulosus mothers against decapentaplegic 2 0.0106 0.0123 0.0123
Echinococcus multilocularis high affinity choline transporter 1 0.0356 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0086 0.0095 0.0095
Brugia malayi hypothetical protein 0.0046 0.0037 0.0076
Schistosoma mansoni alpha glucosidase 0.0075 0.008 0.008
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0054 0.005 0.0225
Trichomonas vaginalis flap endonuclease-1, putative 0.0053 0.0048 0.0124
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Onchocerca volvulus 0.0048 0.0041 0.0149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0069 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Trichomonas vaginalis glucosylceramidase, putative 0.0546 0.0751 0.1939
Echinococcus multilocularis flap endonuclease 1 0.0053 0.0048 0.0048
Echinococcus multilocularis survival motor neuron protein 1 0.1241 0.1741 0.1741
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0038 0.017
Brugia malayi hypothetical protein 0.0026 0.001 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0086 0.0095 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0086 0.0095 0.0193
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0046 0.0038 0.0076
Mycobacterium tuberculosis Probable dehydrogenase 0.0302 0.0402 0.1723
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0011 0.0028
Schistosoma mansoni hypothetical protein 0.0665 0.092 0.092
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0023 0.0006 0.0015
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0008 0.006
Plasmodium falciparum glutathione reductase 0.0132 0.0161 0.0257
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0069 0.0178
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0132 0.0161 0.0686
Trichomonas vaginalis glucosylceramidase, putative 0.0359 0.0484 0.1248
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0046 0.0038 0.0322
Trypanosoma cruzi mitochondrial protein 99, putative 0.0023 0.0006 0.0025
Brugia malayi Bromodomain containing protein 0.0057 0.0053 0.0108
Trypanosoma cruzi cysteine proteinase, putative 0.0054 0.005 0.0225
Echinococcus granulosus peregrin 0.0257 0.0338 0.0338
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0041 0.035
Trichomonas vaginalis glutathione reductase, putative 0.0046 0.0038 0.0097
Schistosoma mansoni ferritin light chain 0.0035 0.0022 0.0022
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0012 0.0045
Trichomonas vaginalis penicillin-binding protein, putative 0.0259 0.0341 0.0881
Schistosoma mansoni hypothetical protein 0.1933 0.2729 0.2729
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0046 0.0037 0.0037
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0006 0.0011
Onchocerca volvulus 0.0028 0.0013 0.0046
Schistosoma mansoni zinc finger protein 0.0041 0.0031 0.0031
Schistosoma mansoni chromobox protein 0.0068 0.0069 0.0069
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0046 0.0038 0.0076
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0041 0.0185
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0026 0.001 0.0019
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0289 0.0384 0.0384
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0236 0.031 0.0309
Echinococcus multilocularis sterol regulatory element binding protein 0.0082 0.009 0.009
Echinococcus granulosus regulator of G protein signaling 7 0.0026 0.001 0.0009
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0269 0.0356 0.161
Plasmodium vivax vivapain-3 0.0054 0.005 0.008
Onchocerca volvulus 0.0046 0.0038 0.0136
Toxoplasma gondii cathepsin CPC1 0.44 0.6244 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0073 0.0188
Echinococcus multilocularis snurportin 1 0.0316 0.0422 0.0422
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0012 0.0025
Brugia malayi Bromodomain containing protein 0.0102 0.0117 0.0238
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0027 0.0012 0.0023
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0035 0.0022 0.0088
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0006 0.0011
Echinococcus multilocularis neutral sphingomyelinase 0.0023 0.0006 0.0006
Loa Loa (eye worm) DIX domain-containing protein 0.0026 0.001 0.0019
Entamoeba histolytica hypothetical protein 0.0337 0.0452 1
Brugia malayi Cathepsin L-like precursor 0.0105 0.0123 0.0249
Brugia malayi MH2 domain containing protein 0.0236 0.031 0.0629
Echinococcus granulosus high affinity choline transporter 1 0.0356 0.0481 0.048
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0006 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.008 0.036
Loa Loa (eye worm) hypothetical protein 0.0046 0.0038 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0013 0.0033
Trichomonas vaginalis ferritin, putative 0.0035 0.0022 0.0056
Trypanosoma cruzi cysteine peptidase, putative 0.0054 0.005 0.0225
Schistosoma mansoni retinoic acid receptor RXR 0.0086 0.0095 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0042 0.0108
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Leishmania major cathepsin L-like protease 0.0105 0.0123 0.0554
Schistosoma mansoni sodium/solute symporter 0.0039 0.0028 0.0028
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.44 0.6244 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0049 0.0042 0.0189
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.003 0.003
Schistosoma mansoni tar DNA-binding protein 0.0661 0.0915 0.0915
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0651 0.0901 0.183
Echinococcus multilocularis importin subunit beta 1 0.003 0.0015 0.0014
Leishmania major trypanothione reductase 0.0132 0.0161 0.0727
Trypanosoma cruzi PAB1-binding protein , putative 0.0644 0.0891 0.4028
Leishmania major mitochondrial DNA polymerase beta 0.1571 0.2212 1
Brugia malayi steroid hormone receptor 0.0086 0.0095 0.0193
Echinococcus multilocularis lysine specific demethylase 6a 0.0077 0.0083 0.0082
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0546 0.0751 0.1527
Plasmodium vivax SET domain protein, putative 0.0247 0.0324 0.0519
Loa Loa (eye worm) nuclear hormone receptor 0.0041 0.003 0.0061
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.006 0.0058 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0259 0.0341 0.1543
Toxoplasma gondii PHD-finger domain-containing protein 0.0239 0.0314 0.0502
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.1063 0.1488 0.1488
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0178 0.0226 0.0584
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.011 0.013 0.0586
Leishmania major hypothetical protein, conserved 0.0023 0.0006 0.0025
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0743 0.1032 0.4667
Echinococcus granulosus lamin 0.0028 0.0013 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0258 0.034 0.034
Toxoplasma gondii type I fatty acid synthase, putative 0.0028 0.0013 0.002
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0023 0.0006 0.0006
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0006 0.0011
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0302 0.0402 0.1723
Echinococcus granulosus Niemann Pick C1 protein 0.0192 0.0246 0.0246
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0269 0.0355 0.0722
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0239 0.0314 0.0314
Echinococcus granulosus phd:f box containing protein 0.0077 0.0083 0.0082
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.011 0.013 0.0586
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0003 0.0005
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0077 0.0083 0.0373
Brugia malayi jmjC domain containing protein 0.0077 0.0083 0.0168
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0023 0.0006 0.0025
Schistosoma mansoni ran 0.0022 0.0003 0.0003
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Loa Loa (eye worm) hypothetical protein 0.1241 0.1741 0.3538
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0071 0.0073 0.0148
Loa Loa (eye worm) MH2 domain-containing protein 0.3471 0.4921 1
Mycobacterium ulcerans lipase LipD 0.0259 0.0341 0.2959
Brugia malayi hypothetical protein 0.0644 0.0891 0.181
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.2219 0.3136 0.6373
Trypanosoma cruzi cruzipain precursor, putative 0.0035 0.0022 0.0099
Trichomonas vaginalis bromodomain-containing protein, putative 0.0178 0.0226 0.0584
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Schistosoma mansoni inositol transporter 0.0039 0.0028 0.0028
Plasmodium falciparum phd finger protein, putative 0.0239 0.0314 0.0502
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0025 0.0008 0.0028
Echinococcus multilocularis GPCR, family 2 0.0651 0.0901 0.0901
Echinococcus multilocularis solute carrier family 5 0.0039 0.0028 0.0028
Brugia malayi photoreceptor-specific nuclear receptor 0.0086 0.0095 0.0193
Entamoeba histolytica cysteine proteinase, putative 0.0054 0.005 0.1099
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0265 0.0351 0.0351
Trichomonas vaginalis CAMK family protein kinase 0.029 0.0386 0.0996
Schistosoma mansoni coup transcription factor 0.0086 0.0095 0.0095
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0046 0.0038 0.0037
Brugia malayi CXXC zinc finger family protein 0.0086 0.0095 0.0193
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0041 0.0904
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0077 0.0083 0.0132
Onchocerca volvulus 0.0105 0.0123 0.0446
Echinococcus granulosus cathepsin l1 0.0071 0.0073 0.0073
Schistosoma mansoni ferritin 0.0035 0.0022 0.0022
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0253 0.0333 0.0677
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0192 0.0246 0.5441
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0041 0.003 0.003
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0003 0.0003
Schistosoma mansoni RAR-like nuclear receptor 0.0086 0.0095 0.0095
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0041 0.035
Plasmodium falciparum thioredoxin reductase 0.0132 0.0161 0.0257
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0006 0.0025
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0047 0.004 0.0179
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0236 0.031 0.0309
Brugia malayi hypothetical protein 0.1241 0.1741 0.3538
Giardia lamblia Dipeptidyl-peptidase I precursor 0.1681 0.2369 0.3794
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.0123 0.0316
Echinococcus granulosus Niemann Pick C1 protein 0.0274 0.0363 0.0363
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0105 0.0123 0.0316
Trichomonas vaginalis glucosylceramidase, putative 0.0546 0.0751 0.1939
Schistosoma mansoni nuclear receptor 0.0041 0.003 0.003
Plasmodium vivax ataxin-2 like protein, putative 0.0644 0.0891 0.1427
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0058 0.0259
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0038 0.017
Echinococcus granulosus cathepsin L 0.0054 0.005 0.005
Onchocerca volvulus Cathepsin L homolog 0.0105 0.0123 0.0446
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0021 0.0003 0.0003
Trypanosoma cruzi cysteine proteinase, putative 0.0054 0.005 0.0225
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0012 0.027
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.008 0.1759
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0016 0.0041
Schistosoma mansoni kinase 0.0147 0.0183 0.0182
Toxoplasma gondii thioredoxin reductase 0.0132 0.0161 0.0257
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0046 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.0123 0.0316
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0076
Leishmania major phosphatidylinositol 3-kinase, putative 0.0049 0.0042 0.0189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0265 0.0351 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0027 0.0068
Loa Loa (eye worm) hypothetical protein 0.0043 0.0034 0.0069
Loa Loa (eye worm) hypothetical protein 0.0046 0.0038 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0016 0.0041
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0016 0.0041
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0034 0.002 0.0041
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0546 0.0751 0.1527
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0221 0.0287 0.1298
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.011 0.013 0.2868
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0086 0.0095 0.0193
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.006 0.0058 0.0259
Brugia malayi jmjC domain containing protein 0.0077 0.0083 0.0168
Loa Loa (eye worm) phosphatidylinositol 3 0.011 0.013 0.0263
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0011
Mycobacterium ulcerans hypothetical protein 0.0048 0.0041 0.035
Toxoplasma gondii LsmAD domain-containing protein 0.0644 0.0891 0.1427
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0105 0.0123 0.0196
Echinococcus granulosus jumonji domain containing protein 0.0333 0.0447 0.0447
Schistosoma mansoni hypothetical protein 0.1933 0.2729 0.2729
Schistosoma mansoni hypothetical protein 0.0023 0.0005 0.0005
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0006 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.0123 0.0316
Echinococcus multilocularis Niemann Pick C1 protein 0.0192 0.0246 0.0246
Trypanosoma brucei trypanothione reductase 0.0132 0.0161 0.0727
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0031 0.014
Plasmodium vivax hypothetical protein, conserved 0.0239 0.0314 0.0502
Brugia malayi MH2 domain containing protein 0.0236 0.031 0.0629
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0031 0.0016 0.0025
Schistosoma mansoni importin beta-1 0.003 0.0015 0.0014
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0058 0.0148
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0006 0.0025
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0041 0.0171
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0009
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0086 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0086 0.0095 0.0193
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.003 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0038 0.017
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0024 0.0006 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0103 0.0265
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0105 0.0123 0.0122
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0075 0.008 0.0127
Mycobacterium ulcerans bacterioferritin BfrA 0.0035 0.0022 0.0183
Brugia malayi Heterochromatin protein 1 0.0068 0.0069 0.014
Echinococcus multilocularis dna polymerase kappa 0.006 0.0058 0.0057
Trichomonas vaginalis ran, putative 0.0022 0.0003 0.0009
Schistosoma mansoni neutral sphingomyelinase 0.0023 0.0006 0.0006
Loa Loa (eye worm) cysteine protease 0.0105 0.0123 0.0249
Echinococcus multilocularis FTZ F1 alpha 0.0086 0.0095 0.0095
Brugia malayi GH02984p 0.0356 0.0481 0.0976
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0084 0.0093 0.0092
Schistosoma mansoni cpg binding protein 0.0093 0.0105 0.0105
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0038 0.017
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0012 0.0032
Toxoplasma gondii hypothetical protein 0.0253 0.0334 0.0534
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0085 0.0093 0.0093
Onchocerca volvulus 0.0253 0.0333 0.1214
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0027 0.0012 0.0253
Mycobacterium ulcerans thioesterase TesA 0.0021 0.0002 0.0009
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.011 0.013 0.013
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.003 0.011
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.008 0.0206
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0023 0.0006 0.0122
Toxoplasma gondii cathepsin CPC2 0.1681 0.2369 0.3794
Loa Loa (eye worm) hypothetical protein 0.0259 0.0341 0.0693
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0041 0.003 0.003
Entamoeba histolytica acetyltransferase, GNAT family 0.0161 0.0202 0.4465
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0066 0.0169
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0011
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0058 0.0259
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0034 0.002 0.0041
Brugia malayi Cathepsin L-like precursor 0.0105 0.0123 0.0249
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0009
Loa Loa (eye worm) fatty acid synthase 0.0024 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0025
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.029 0.0386 0.0784
Brugia malayi CCR4 0.0023 0.0006 0.0012
Brugia malayi hypothetical protein 0.0337 0.0452 0.0919
Echinococcus granulosus thioredoxin glutathione reductase 0.0133 0.0162 0.0161
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0025 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Giardia lamblia hypothetical protein 0.0023 0.0006 0.0009
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0221 0.0287 0.1298
Brugia malayi FAT domain containing protein 0.0021 0.0003 0.0005
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0026 0.001 0.0019
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0054 0.005 0.005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0086 0.0095 0.0193
Loa Loa (eye worm) hypothetical protein 0.0265 0.0351 0.0713
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.005 0.0225
Onchocerca volvulus 0.1945 0.2744 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.005 0.0129
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0012 0.0032
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0743 0.1032 0.4667
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0041 0.035
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0743 0.1032 0.4667
Schistosoma mansoni DNA polymerase eta 0.006 0.0058 0.0057
Onchocerca volvulus 0.0196 0.0252 0.0917
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Mycobacterium tuberculosis Conserved protein 0.0259 0.0341 0.1461
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0109 0.0127 0.0127
Schistosoma mansoni lamin 0.0028 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0077 0.0083 0.0168
Echinococcus multilocularis PHD finger protein rhinoceros 0.0239 0.0314 0.0314
Loa Loa (eye worm) acetyltransferase 0.06 0.0828 0.1681
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0038 0.017
Trichomonas vaginalis D-aminoacylase, putative 0.0259 0.0341 0.0881
Trypanosoma cruzi polo-like protein kinase, putative 0.029 0.0386 0.1745
Echinococcus granulosus expressed protein 0.0035 0.0022 0.0022
Echinococcus granulosus histone acetyltransferase KAT2B 0.0178 0.0226 0.0226
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0003 0.0003
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0009
Echinococcus multilocularis chromobox protein 1 0.0068 0.0069 0.0069
Loa Loa (eye worm) nuclear receptor NHR-67 0.0041 0.003 0.0061
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0045
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0007 0.0029
Toxoplasma gondii FATC domain-containing protein 0.0042 0.0032 0.0051
Mycobacterium tuberculosis Conserved protein 0.0259 0.0341 0.1461
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0013 0.0026
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0046 0.0038 0.0037
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0046 0.0038 0.0322
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0302 0.0402 0.8933
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0069 0.0178
Brugia malayi tailless protein 0.0041 0.003 0.0061
Trypanosoma brucei PAB1-binding protein , putative 0.0644 0.0891 0.4028
Mycobacterium ulcerans esterase/lipase LipP 0.0259 0.0341 0.2959
Onchocerca volvulus 0.0086 0.0095 0.0345
Loa Loa (eye worm) hypothetical protein 0.0071 0.0073 0.0148
Schistosoma mansoni nuclear hormone receptor 0.0041 0.003 0.003
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0335 0.045 1
Brugia malayi TAR-binding protein 0.0661 0.0915 0.1859
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0023 0.0006 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0546 0.0751 0.1939
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0046 0.0038 0.0097
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0084 0.0093 0.0092
Schistosoma mansoni smad1 5 8 and 0.0236 0.031 0.0309
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0046 0.0038 0.0038
Echinococcus granulosus neutral alpha glucosidase AB 0.0075 0.008 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0103 0.0265
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0023 0.0006 0.0025
Schistosoma mansoni cathepsin F (C01 family) 0.0105 0.0123 0.0122
Onchocerca volvulus 0.0105 0.0123 0.0446
Loa Loa (eye worm) hypothetical protein 0.0259 0.0341 0.0693
Schistosoma mansoni flap endonuclease-1 0.0048 0.0041 0.0041
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0022 0.0099
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.5832 0.8286 0.8286
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0006 0.0011
Schistosoma mansoni Smad4 0.0106 0.0123 0.0123
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0177 0.0457
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0023 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0378 0.0511 0.1319
Loa Loa (eye worm) fibroinase 0.0105 0.0123 0.0249
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0046 0.0038 0.017
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0006 0.0011
Onchocerca volvulus 0.0023 0.0006 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.0019
Echinococcus granulosus chromobox protein 1 0.0068 0.0069 0.0069
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0049 0.0042 0.0042
Echinococcus granulosus cysteine protease 0.0054 0.005 0.005
Onchocerca volvulus Cathepsin F homolog 0.0105 0.0123 0.0446
Trypanosoma brucei glucosidase, putative 0.0075 0.008 0.036
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0024 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Schistosoma mansoni nuclear receptor nhr-48 0.0041 0.003 0.003
Schistosoma mansoni nuclear receptor 0.0041 0.003 0.003
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0041 0.003 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0086 0.0095 0.0193
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0106 0.0123 0.0448
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0122
Entamoeba histolytica Ran family GTPase 0.0022 0.0003 0.0073
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0006 0.0025
Onchocerca volvulus 0.0105 0.0123 0.0446
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0337 0.0452 0.0452
Echinococcus multilocularis protein dispatched 1 0.0094 0.0106 0.0106
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0083 0.0082
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0178 0.0226 0.0362
Echinococcus multilocularis cathepsin L cysteine protease 0.0105 0.0123 0.0122
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0046 0.0038 0.0076
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0339 0.0456 0.0926
Brugia malayi exodeoxyribonuclease III family protein 0.0115 0.0137 0.0278
Mycobacterium leprae Polyketide synthase Pks13 0.0037 0.0025 0.054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0069 0.0178
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.0015 0.0014
Echinococcus multilocularis lysosomal alpha glucosidase 0.0339 0.0456 0.0455
Echinococcus multilocularis Niemann Pick C1 protein 0.0274 0.0363 0.0363
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0086 0.0095 0.0095
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.1063 0.1488 0.3025
Loa Loa (eye worm) hypothetical protein 0.0048 0.0041 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.0546 0.0751 0.1939
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.0015 0.0014
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0006 0.0025
Schistosoma mansoni dishevelled 0.0026 0.001 0.0009
Loa Loa (eye worm) jmjC domain-containing protein 0.0494 0.0677 0.1376
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Trichomonas vaginalis esterase, putative 0.0259 0.0341 0.0881
Brugia malayi beta-lactamase family protein 0.0259 0.0341 0.0693
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Loa Loa (eye worm) hypothetical protein 0.0259 0.0341 0.0693
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0529 0.0727 0.2647
Echinococcus granulosus sterol regulatory element binding protein 0.0082 0.009 0.009
Echinococcus granulosus Smad4 0.0236 0.031 0.0309
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0021 0.0085
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.003 0.003
Leishmania major hypothetical protein, conserved 0.0644 0.0891 0.4028
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0023 0.0006 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.0123 0.0316
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0006 0.0011
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0046 0.0038 0.017
Echinococcus multilocularis neuropeptide receptor A26 0.0515 0.0707 0.0706
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0046 0.0038 0.0076
Echinococcus granulosus intermediate filament protein 0.0028 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0008 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Echinococcus granulosus tar DNA binding protein 0.0661 0.0915 0.0915
Schistosoma mansoni hypothetical protein 0.1407 0.1978 0.1978
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0069 0.0178
Schistosoma mansoni phosphatidylserine receptor 0.0077 0.0083 0.0082
Plasmodium falciparum flap endonuclease 1 0.0053 0.0048 0.0077
Brugia malayi chromobox protein homolog 3 0.0038 0.0027 0.0054
Echinococcus multilocularis mothers against decapentaplegic 6 0.0106 0.0123 0.0123
Trypanosoma brucei unspecified product 0.0041 0.0031 0.014
Leishmania major hypothetical protein, conserved 0.0259 0.0341 0.1543
Plasmodium vivax vivapain-2 0.0105 0.0123 0.0196
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0041 0.035
Onchocerca volvulus 0.0039 0.0028 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0086 0.0095 0.0193
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0026 0.001 0.0009
Onchocerca volvulus 0.0105 0.0123 0.0446
Loa Loa (eye worm) hypothetical protein 0.0048 0.0041 0.0083
Schistosoma mansoni hypothetical protein 0.0316 0.0422 0.0422
Schistosoma mansoni hypothetical protein 0.0651 0.0901 0.0901
Loa Loa (eye worm) hypothetical protein 0.0066 0.0067 0.0136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Brugia malayi beta-lactamase 0.0259 0.0341 0.0693
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0259 0.0341 0.0341
Echinococcus multilocularis lysine specific demethylase 5A 0.029 0.0385 0.0385
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0027 0.0012 0.0052
Brugia malayi Nuclear hormone receptor E75 0.0041 0.003 0.0061
Brugia malayi ecdysone receptor 0.0041 0.003 0.0061
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0335 0.045 0.1929
Echinococcus granulosus cathepsin L cysteine proteinase 0.0105 0.0123 0.0122
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0178 0.0226 0.0362
Trichomonas vaginalis glucosylceramidase, putative 0.0359 0.0484 0.1248
Schistosoma mansoni cathepsin F (C01 family) 0.0105 0.0123 0.0122
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0784 0.109 0.109
Plasmodium falciparum DNase I-like protein, putative 0.0023 0.0006 0.0009
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0046 0.0038 0.0037
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0006 0.0011
Mycobacterium leprae Probable polyketide synthase Pks1 0.0026 0.001 0.0201
Brugia malayi hypothetical protein 0.0041 0.003 0.0061
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0037 0.0025 0.0102
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0011
Trypanosoma cruzi major cysteine proteinase, putative 0.0116 0.0138 0.0624
Toxoplasma gondii target of rapamycin (TOR), putative 0.0087 0.0096 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Echinococcus granulosus serine:threonine protein kinase PLK1 0.029 0.0386 0.0386
Loa Loa (eye worm) MH1 domain-containing protein 0.0106 0.0123 0.025
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0651 0.0901 0.0901
Echinococcus granulosus snurportin 1 0.0316 0.0422 0.0422
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0058 0.0493
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0177 0.0457
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0105 0.0123 0.0249
Leishmania major cathepsin L-like protease 0.0105 0.0123 0.0554
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Echinococcus multilocularis smad 0.0236 0.031 0.0309
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0077 0.0083 0.0082
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0023 0.0006 0.0025
Treponema pallidum NADH oxidase 0.0046 0.0038 0.2443
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0015 0.0023
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0046 0.0038 0.0037
Trichomonas vaginalis mercuric reductase, putative 0.0046 0.0038 0.0097
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0006 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0247 0.0324 0.0324
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0016 0.0041
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0039 0.0028 0.0028
Schistosoma mansoni fkbp-rapamycin associated protein 0.0027 0.0012 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.008 0.0206
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0086 0.0095 0.0095
Onchocerca volvulus Fatty acid synthase homolog 0.0044 0.0036 0.013
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0006 0.0025
Schistosoma mansoni terminal deoxycytidyl transferase 0.006 0.0058 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0042 0.0108
Schistosoma mansoni bromodomain containing protein 0.0089 0.0099 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0096 0.0247
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0259 0.0341 0.1461
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.0015 0.0014
Echinococcus multilocularis Smad4 0.0236 0.031 0.0309
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0096 0.0247
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.44 0.6244 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0046 0.0038 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0651 0.0901 0.0901
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Schistosoma mansoni Smad4 0.0236 0.031 0.0309
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0054 0.005 0.005
Loa Loa (eye worm) jmjC domain-containing protein 0.0297 0.0395 0.0803
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.1063 0.1488 0.3025
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0023 0.0006 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0058 0.0259
Plasmodium falciparum histone acetyltransferase GCN5 0.0161 0.0202 0.0323
Onchocerca volvulus 0.0041 0.003 0.011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0038 0.017
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.008 0.0206
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0086 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0046 0.0038 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.0123 0.0316
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0086 0.0095 0.0095
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0006 0.0025
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Mycobacterium ulcerans hypothetical protein 0.0827 0.1152 1
Entamoeba histolytica hypothetical protein 0.0337 0.0452 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0075 0.008 0.008
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.003 0.003
Schistosoma mansoni ap endonuclease 0.0115 0.0137 0.0137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0086 0.0095 0.0193
Giardia lamblia DINP protein human, muc B family 0.006 0.0058 0.0092
Echinococcus granulosus mothers against decapentaplegic 5 0.0236 0.031 0.0309
Brugia malayi Niemann-Pick C1 protein precursor 0.0192 0.0246 0.05
Brugia malayi follicle stimulating hormone receptor 0.0269 0.0355 0.0722
Echinococcus multilocularis expressed protein 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0024
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0023 0.0006 0.0025
Toxoplasma gondii cathepsin CPL 0.0105 0.0123 0.0196
Plasmodium vivax unspecified product 0.0054 0.005 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0103 0.0265
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0046 0.0038 0.0037
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.011 0.013 0.2868
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.005 0.0129
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0046 0.0038 0.0037
Mycobacterium tuberculosis Conserved hypothetical protein 0.0827 0.1152 0.4943
Giardia lamblia Dipeptidyl-peptidase I precursor 0.1681 0.2369 0.3794
Trichomonas vaginalis CAMK family protein kinase 0.029 0.0386 0.0996
Echinococcus granulosus tumor protein p63 0.6993 0.9942 0.9942
Brugia malayi nuclear receptor NHR-88 0.0041 0.003 0.0061
Mycobacterium ulcerans polyketide synthase Pks13 0.0037 0.0025 0.0211
Brugia malayi Smad1 0.0236 0.031 0.0629
Mycobacterium tuberculosis Probable lipase LipE 0.0259 0.0341 0.1461
Schistosoma mansoni ran 0.0022 0.0003 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.1063 0.1488 0.1488
Echinococcus multilocularis peregrin 0.0257 0.0338 0.0338
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0009
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.011 0.013 0.013
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0016 0.0016
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.44 0.6244 0.6244
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0016 0.0016
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0812 0.113 0.113
Echinococcus granulosus neutral sphingomyelinase 0.0023 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0086 0.0095 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0069 0.0178
Schistosoma mansoni ap endonuclease 0.0115 0.0137 0.0137
Brugia malayi Papain family cysteine protease containing protein 0.0105 0.0123 0.0249
Brugia malayi Cathepsin L-like precursor 0.0105 0.0123 0.0249
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.006 0.0058 0.0117
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0037 0.0025 0.0102
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0007 0.0017
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0042 0.0032 0.0144
Echinococcus multilocularis nuclear receptor nhr 48 0.0041 0.003 0.003
Brugia malayi Thioredoxin reductase 0.0132 0.0161 0.0327
Plasmodium vivax vivapain-2 0.0105 0.0123 0.0196
Echinococcus multilocularis thioredoxin glutathione reductase 0.0133 0.0162 0.0161
Echinococcus granulosus histone lysine methyltransferase setb 0.0265 0.0351 0.0351
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0195 0.025 0.025
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0012 0.0032
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0046 0.0038 0.0037
Schistosoma mansoni cpg binding protein 0.0086 0.0095 0.0095
Brugia malayi regulator of G-protein signaling egl-10 0.0026 0.001 0.0019
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0003 0.0005
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0023 0.0006 0.0025
Giardia lamblia Inositol 5-phosphatase 4 0.0023 0.0006 0.0009
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0007 0.0017
Schistosoma mansoni cript-related 0.0023 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0103 0.0265
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0042 0.0108
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0026 0.001 0.0201
Loa Loa (eye worm) hypothetical protein 0.0086 0.0095 0.0193
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.44 0.6244 1
Trypanosoma cruzi cysteine peptidase, putative 0.0202 0.0261 0.1177
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.003 0.003
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0023 0.0006 0.0006
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0035 0.0022 0.0468
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0082 0.009 0.0182
Loa Loa (eye worm) hypothetical protein 0.0356 0.0481 0.0976
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0046 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0086 0.0095 0.0193
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0046 0.0038 0.0037
Onchocerca volvulus Cathepsin L homolog 0.0105 0.0123 0.0446
Brugia malayi Steroid receptor seven-up type 2 0.0086 0.0095 0.0193
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0053 0.0048 0.0217
Trichomonas vaginalis glucosylceramidase, putative 0.0378 0.0511 0.1319
Brugia malayi Cathepsin L-like precursor 0.0105 0.0123 0.0249
Schistosoma mansoni phd/f-box containing protein 0.0077 0.0083 0.0082
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0025 0.0008 0.0015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0021 0.0085
Echinococcus granulosus importin subunit beta 1 0.003 0.0015 0.0014
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0046 0.0038 0.0097
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0015 0.0065
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0006 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0202 0.0261 0.1177
Brugia malayi Glycosyl hydrolases family 31 protein 0.0339 0.0456 0.0926
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0066 0.0169
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0302 0.0402 0.1723
Plasmodium vivax glutathione reductase, putative 0.0132 0.0161 0.0257
Brugia malayi intermediate filament protein 0.0028 0.0013 0.0026
Echinococcus multilocularis protein patched 0.0082 0.009 0.009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0001 0.0003
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0003 0.0015
Trichomonas vaginalis D-aminoacylase, putative 0.0259 0.0341 0.0881
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.0123 0.0316
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0058 0.0117
Echinococcus granulosus lysosomal alpha glucosidase 0.0339 0.0456 0.0455
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0046 0.0038 0.0037
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0075 0.008 0.0162
Brugia malayi nuclear hormone receptor family member nhr-6 0.0041 0.003 0.0061
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0046 0.0038 0.006
Schistosoma mansoni hypothetical protein 0.0023 0.0006 0.0006
Plasmodium falciparum cysteine proteinase falcipain 3 0.0105 0.0123 0.0196
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0812 0.113 0.113
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0122
Loa Loa (eye worm) MH2 domain-containing protein 0.0106 0.0123 0.025
Brugia malayi Nuclear hormone receptor-like 1 0.0086 0.0095 0.0193
Loa Loa (eye worm) hypothetical protein 0.041 0.0557 0.1133
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0031 0.0079
Plasmodium vivax hypothetical protein, conserved 0.0259 0.0341 0.0546
Echinococcus multilocularis cathepsin L 0.0054 0.005 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0012 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0076 0.0196
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0029 0.0028
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0058 0.0259
Echinococcus granulosus geminin 0.1933 0.2729 0.2729
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0115 0.0137 0.0619
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0046 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0023
Leishmania major cathepsin L-like protease 0.0105 0.0123 0.0554
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0003 0.0005
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0077 0.0083 0.0373
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0023 0.0006 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0359 0.0484 0.1248
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0091 0.0103 0.0464
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0037 0.0076
Schistosoma mansoni smad 0.0236 0.031 0.0309
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.1063 0.1488 0.1488
Trypanosoma brucei unspecified product 0.006 0.0058 0.0259
Mycobacterium ulcerans hypothetical protein 0.0259 0.0341 0.2959
Plasmodium vivax importin-beta 2, putative 0.003 0.0015 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0359 0.0484 0.1248
Echinococcus granulosus mothers against decapentaplegic 6 0.0106 0.0123 0.0123
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Mycobacterium ulcerans polyketide synthase 0.0025 0.0008 0.006
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0038 0.017
Brugia malayi CHE-14 protein 0.0082 0.009 0.0182
Schistosoma mansoni dishevelled 0.0026 0.001 0.0009
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0038 0.017
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0023 0.0006 0.0006
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0784 0.109 0.109
Echinococcus multilocularis expressed conserved protein 0.018 0.0229 0.0229
Plasmodium falciparum glutathione reductase 0.0046 0.0038 0.006
Mycobacterium tuberculosis Conserved hypothetical protein 0.006 0.0058 0.0242
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0039 0.0028 0.0028
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0265 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0076
Brugia malayi acetyltransferase, GNAT family protein 0.06 0.0828 0.1681
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0006 0.0009
Schistosoma mansoni steroid hormone receptor ad4bp 0.0086 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0651 0.0901 0.183
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0029
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0665 0.092 0.092
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.1681 0.2369 0.3794
Echinococcus granulosus sodium:glucose cotransporter 2 0.0039 0.0028 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0546 0.0751 0.1939
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0058 0.0259
Entamoeba histolytica cysteine protease, putative 0.0105 0.0123 0.271
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0046 0.0037 0.0076
Brugia malayi Importin beta-1 subunit 0.003 0.0015 0.0029
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0259 0.0341 0.0341
Schistosoma mansoni carbon catabolite repressor protein 0.0023 0.0006 0.0006
Brugia malayi Cathepsin L-like precursor 0.0105 0.0123 0.0249
Loa Loa (eye worm) Smad1 0.0236 0.031 0.0629
Brugia malayi MH1 domain containing protein 0.0131 0.0159 0.0323
Toxoplasma gondii PHD-finger domain-containing protein 0.0239 0.0314 0.0502
Schistosoma mansoni tar DNA-binding protein 0.0661 0.0915 0.0915
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0046 0.0038 0.0037
Echinococcus multilocularis phd:f box containing protein 0.0077 0.0083 0.0082
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0046 0.0038 0.0037
Plasmodium vivax flap endonuclease 1, putative 0.0053 0.0048 0.0077
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0167 0.0211 0.0953
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0037 0.0076
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0046 0.0038 0.0076
Brugia malayi DIX domain containing protein 0.0026 0.001 0.0019
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0008 0.006
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.005 0.0043 0.0194
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Loa Loa (eye worm) hypothetical protein 0.0024 0.0007 0.0014
Mycobacterium leprae Probable lipase LipE 0.0259 0.0341 0.7577
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.013 0.0335
Schistosoma mansoni serine/threonine protein kinase 0.029 0.0386 0.0386
Echinococcus multilocularis mothers against decapentaplegic 5 0.0236 0.031 0.0309
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.0123 0.271
Giardia lamblia GTOR 0.011 0.013 0.0208
Echinococcus granulosus ecdysone induced protein 78C 0.0086 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0048
Loa Loa (eye worm) hypothetical protein 0.0259 0.0341 0.0693
Schistosoma mansoni lamin 0.0028 0.0013 0.0013
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0012 0.0055
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0023 0.0006 0.0015
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0008 0.0028
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0259 0.0341 0.2959
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0316 0.0422 0.0858
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0086 0.0095 0.0193
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0042 0.0032 0.0065
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.011 0.013 0.0586
Trichomonas vaginalis maltase-glucoamylase, putative 0.0075 0.008 0.0206
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0086 0.0095 0.0095
Echinococcus granulosus segment polarity protein dishevelled 0.0026 0.001 0.0009
Brugia malayi MH1 domain containing protein 0.0236 0.031 0.0629
Echinococcus multilocularis traf and tnf receptor associated protein 0.0023 0.0006 0.0006
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0039 0.0028 0.0045
Schistosoma mansoni hypothetical protein 0.0079 0.0086 0.0085
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0122
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.011 0.013 0.0586
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0221 0.0287 0.1298
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.011 0.013 0.0263
Brugia malayi RNA, U transporter 1 0.0084 0.0092 0.0187
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0032 0.0019 0.0083
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0041 0.0896
Echinococcus multilocularis zinc finger protein 0.0041 0.0031 0.0031
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0039 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.006 0.0058 0.0117
Entamoeba histolytica cysteine proteinase, putative 0.0054 0.005 0.1099
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0023 0.0006 0.0015
Echinococcus granulosus JmjC domain containing protein 4 0.0077 0.0083 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.009 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0069 0.0178
Echinococcus granulosus TGF beta signal transducer SmadC 0.0236 0.031 0.0309
Brugia malayi ecdysteroid receptor 0.0086 0.0095 0.0193
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0247 0.0324 0.0324
Entamoeba histolytica hypothetical protein 0.0337 0.0452 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0086 0.0095 0.0095
Echinococcus multilocularis expressed protein 0.0046 0.0038 0.0037
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.0012 0.0032
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1709 0.2408 0.4894
Treponema pallidum bacterioferrin (TpF1) 0.0035 0.0022 0.1228
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0035 0.0022 0.0045
Entamoeba histolytica cysteine protease, putative 0.0054 0.005 0.1099
Schistosoma mansoni synaptojanin 0.0023 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0651 0.0901 0.0901
Trypanosoma cruzi polo-like protein kinase, putative 0.029 0.0386 0.1745
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.011 0.013 0.013
Brugia malayi jmjC domain containing protein 0.0077 0.0083 0.0168
Brugia malayi Glycosyl hydrolases family 31 protein 0.0075 0.008 0.0162
Echinococcus granulosus cathepsin L cysteine protease 0.0054 0.005 0.005
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0026 0.001 0.0034
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0115 0.0137 0.0219
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0076
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0178 0.0226 0.0362
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0086 0.0095 0.0095
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0007 0.0017
Brugia malayi nuclear receptor RXR 0.0041 0.003 0.0061
Schistosoma mansoni microtubule-associated protein tau 0.7034 1 1
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0027 0.0012 0.0011
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0058 0.0259
Brugia malayi F/Y-rich N-terminus family protein 0.0116 0.0137 0.0279
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0115 0.0137 0.3027
Brugia malayi jmjC domain containing protein 0.0077 0.0083 0.0168
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0058 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Brugia malayi Cathepsin L-like precursor 0.0035 0.0022 0.0045
Loa Loa (eye worm) G protein alpha subunit 3 0.0046 0.0038 0.0076
Schistosoma mansoni nuclear hormone receptor 0.0041 0.003 0.003
Echinococcus granulosus ferritin 0.0035 0.0022 0.0022
Brugia malayi SET domain containing protein 0.0022 0.0004 0.0007
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0259 0.0341 0.1461
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0023 0.0006 0.0015
Schistosoma mansoni smad1 5 8 and 0.0236 0.031 0.0309
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0046 0.0038 0.0076
Plasmodium falciparum ataxin-2 like protein, putative 0.0644 0.0891 0.1427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Brugia malayi Nuclear hormone receptor E75 0.0041 0.003 0.0061
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0086 0.0095 0.0095
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0259 0.0341 0.0693
Onchocerca volvulus 0.0259 0.0341 0.1243
Trichomonas vaginalis Phospholipase C precursor, putative 0.0023 0.0006 0.0015
Trypanosoma brucei polo-like protein kinase 0.029 0.0386 0.1745
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0024 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Brugia malayi cathepsin F-like cysteine proteinase 0.0035 0.0022 0.0045
Brugia malayi N-terminal motif family protein 0.0529 0.0727 0.1476
Loa Loa (eye worm) hypothetical protein 0.0077 0.0083 0.0168
Leishmania major cathepsin L-like protease 0.0105 0.0123 0.0554
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0046 0.0038 0.0037
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0025 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0086 0.0095 0.0193
Plasmodium falciparum cysteine proteinase falcipain 1 0.0054 0.005 0.008
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0013 0.0026
Schistosoma mansoni patched 1 0.0082 0.009 0.009
Brugia malayi Pre-SET motif family protein 0.1709 0.2408 0.4894
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0003 0.0008
Echinococcus multilocularis cathepsin L cysteine protease 0.0105 0.0123 0.0122
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0048
Loa Loa (eye worm) hypothetical protein 0.0046 0.0038 0.0076
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.006 0.0058 0.0057
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0096 0.0247
Mycobacterium ulcerans beta-lactamase 0.0259 0.0341 0.2959
Onchocerca volvulus Putative neutral sphingomyelinase 0.0023 0.0006 0.002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0038 0.1385
Loa Loa (eye worm) hypothetical protein 0.0644 0.0891 0.181
Echinococcus multilocularis segment polarity protein dishevelled 0.0026 0.001 0.0009
Brugia malayi beta-lactamase family protein 0.0259 0.0341 0.0693
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0049 0.0042 0.0042
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0038 0.017
Echinococcus granulosus expressed conserved protein 0.018 0.0229 0.0229
Trichomonas vaginalis penicillin-binding protein, putative 0.0259 0.0341 0.0881
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.029 0.0386 0.0386
Echinococcus granulosus dnaJ subfamily B 0.0815 0.1134 0.1134
Echinococcus granulosus dna polymerase kappa 0.006 0.0058 0.0057
Brugia malayi latrophilin 2 splice variant baaae 0.1407 0.1978 0.402
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0009
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0037 0.0025 0.0104
Echinococcus multilocularis thyroid hormone receptor alpha 0.0751 0.1043 0.1043
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0665 0.092 0.092
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0025 0.0008 0.0153
Mycobacterium tuberculosis Probable oxidoreductase 0.0335 0.045 0.1929
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0041 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.2738 0.3875 1
Plasmodium falciparum thioredoxin reductase 0.0046 0.0038 0.006
Brugia malayi AF-10 protein 0.0078 0.0084 0.017
Echinococcus multilocularis neuropeptide s receptor 0.0515 0.0707 0.0706
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0202 0.0261 0.1177
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0046 0.0037 0.0037
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0006 0.0011
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0046 0.0038 0.0037
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0012 0.0032
Mycobacterium tuberculosis Probable reductase 0.0302 0.0402 0.1723
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0105 0.0123 0.0316
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1571 0.2212 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.029 0.0386 0.1406
Echinococcus multilocularis microtubule associated protein 2 0.7034 1 1
Schistosoma mansoni hypothetical protein 0.0079 0.0086 0.0085
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0012 0.0032
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0025 0.0008 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.0123 0.0316
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0086 0.0095 0.0347
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0038 0.017
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0029 0.0028
Loa Loa (eye worm) beta-lactamase 0.0259 0.0341 0.0693
Brugia malayi MH2 domain containing protein 0.3471 0.4921 1
Mycobacterium tuberculosis Conserved protein 0.0259 0.0341 0.1461
Schistosoma mansoni cpg binding protein 0.0093 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.0019
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0046 0.0038 0.0097
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0115 0.0137 0.0278
Trypanosoma cruzi mitochondrial protein 99, putative 0.0023 0.0006 0.0025
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0046 0.0038 0.0097
Onchocerca volvulus 0.0046 0.0038 0.0136
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0011
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.006 0.0058 0.0057
Echinococcus granulosus nuclear receptor nhr 48 0.0041 0.003 0.003
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0024 0.0006 0.0023
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0023 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0259 0.0341 0.0693
Onchocerca volvulus 0.0105 0.0123 0.0446
Leishmania major cathepsin L-like protease 0.0105 0.0123 0.0554
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.0123 0.0316
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0046 0.0038 0.0076
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0054 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0072 0.0187
Loa Loa (eye worm) MH2 domain-containing protein 0.0236 0.031 0.0629
Loa Loa (eye worm) hypothetical protein 0.0086 0.0095 0.0193
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0053 0.0048 0.0217
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0023 0.0023
Mycobacterium ulcerans polyketide synthase 0.0026 0.001 0.0079
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0046 0.0038 0.0037
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.003 0.011
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0046 0.0037 0.0037
Echinococcus granulosus histone acetyltransferase KAT2B 0.058 0.08 0.08
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0046 0.0038 0.006
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0046 0.0038 0.0097
Loa Loa (eye worm) hypothetical protein 0.0046 0.0038 0.0076
Brugia malayi Pre-SET motif family protein 0.0247 0.0324 0.0658
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.001 0.0037
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0049 0.0042 0.0189
Echinococcus multilocularis cpg binding protein 0.0093 0.0105 0.0105
Onchocerca volvulus 0.0105 0.0123 0.0446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0042 0.0108
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0023 0.0006 0.0015
Plasmodium falciparum importin beta, putative 0.003 0.0015 0.0023
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0003 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0096 0.0247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0012 0.003
Echinococcus granulosus cpg binding protein 0.0093 0.0105 0.0105
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0023 0.0006 0.0009
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0046 0.0038 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0086 0.0095 0.0193
Echinococcus multilocularis serine protein kinase ATM 0.0042 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0069 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0069 0.0178
Trypanosoma cruzi trypanothione reductase, putative 0.0132 0.0161 0.0727
Onchocerca volvulus 0.0259 0.0341 0.1243
Loa Loa (eye worm) hypothetical protein 0.0041 0.003 0.0061
Leishmania major DNA polymerase kappa, putative 0.006 0.0058 0.0259
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0077 0.0083 0.0132
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0003 0.0007
Plasmodium vivax thioredoxin reductase, putative 0.0132 0.0161 0.0257
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0046 0.0038 0.017
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0086 0.0095 0.0193
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.011 0.013 0.0586
Onchocerca volvulus Bile acid receptor homolog 0.0086 0.0095 0.0347
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0041 0.035
Schistosoma mansoni apoferritin-2 0.0035 0.0022 0.0022
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0023 0.0006 0.0015
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0023 0.0006 0.0025
Echinococcus multilocularis tar DNA binding protein 0.0661 0.0915 0.0915
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0661 0.0915 0.1859
Loa Loa (eye worm) hypothetical protein 0.0131 0.0159 0.0323
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0035 0.0022 0.0088
Echinococcus multilocularis dnaJ subfamily B 0.0815 0.1134 0.1134
Loa Loa (eye worm) hypothetical protein 0.0086 0.0095 0.0193
Brugia malayi hypothetical protein 0.0046 0.0038 0.0076
Loa Loa (eye worm) hypothetical protein 0.0086 0.0095 0.0193
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0016 0.0041
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0085 0.0093 0.0093
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0041 0.035
Echinococcus granulosus solute carrier family 5 0.0039 0.0028 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0086 0.0095 0.0193
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.44 0.6244 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0008
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0023 0.0023
Entamoeba histolytica cysteine proteinase 1, putative 0.0054 0.005 0.1099
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0023 0.0006 0.0011
Echinococcus granulosus zinc finger protein 0.0041 0.0031 0.0031
Echinococcus multilocularis tumor protein p63 0.6993 0.9942 0.9942
Echinococcus multilocularis mothers against decapentaplegic 2 0.0106 0.0123 0.0123
Brugia malayi Cathepsin L-like precursor 0.0071 0.0073 0.0148
Schistosoma mansoni jumonji domain containing protein 0.0623 0.086 0.086
Toxoplasma gondii histone lysine methyltransferase SET1 0.0189 0.0242 0.0387
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.1024 0.1432 0.2909
Loa Loa (eye worm) hypothetical protein 0.0085 0.0094 0.0191
Schistosoma mansoni ferritin 0.0035 0.0022 0.0022
Onchocerca volvulus 0.0071 0.0073 0.0265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.0123 0.0316
Giardia lamblia Encystation-specific protease 0.1681 0.2369 0.3794
Schistosoma mansoni protein phosphatase 2C 0.0077 0.0083 0.0082
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0115 0.0137 0.0137
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0049 0.0042 0.0189
Schistosoma mansoni hypothetical protein 0.0253 0.0333 0.0333
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0046 0.0038 0.0037
Trichomonas vaginalis set domain proteins, putative 0.1945 0.2744 0.7082
Brugia malayi jmjC domain containing protein 0.0784 0.109 0.2215
Echinococcus granulosus jumonji domain containing 1A 0.0077 0.0083 0.0082
Echinococcus granulosus Pleckstrin G protein interacting region 0.0026 0.001 0.0009
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0086 0.0095 0.0095
Onchocerca volvulus 0.1024 0.1432 0.5216
Loa Loa (eye worm) latrophilin receptor protein 2 0.0651 0.0901 0.183
Trypanosoma brucei RNA editing exonuclease 2 0.0023 0.0006 0.0025
Onchocerca volvulus 0.0105 0.0123 0.0446
Brugia malayi MH2 domain containing protein 0.0106 0.0123 0.025
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0046 0.0038 0.0076
Leishmania major RNA-editing complex protein MP100, putative 0.0023 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0192 0.0246 0.05
Leishmania major pantothenate kinase subunit, putative 0.0025 0.0008 0.0038
Leishmania major cathepsin L-like protease 0.0202 0.0261 0.1177
Echinococcus multilocularis deoxyribonuclease 1 2 0.0023 0.0006 0.0006
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0026 0.001 0.0037
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.001 0.0079
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0046 0.0038 0.0157
Schistosoma mansoni synaptojanin 0.0023 0.0006 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0058 0.0259
Trichomonas vaginalis CAMK family protein kinase 0.029 0.0386 0.0996
Echinococcus granulosus synaptojanin 1 0.0023 0.0006 0.0006
Loa Loa (eye worm) transcription factor SMAD2 0.3471 0.4921 1
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0006 0.0009
Leishmania major hypothetical protein, conserved 0.0077 0.0083 0.0373
Entamoeba histolytica protein kinase rad3, putative 0.0027 0.0012 0.0253
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0049 0.0042 0.0189
Loa Loa (eye worm) flap endonuclease-1 0.0053 0.0048 0.0098
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0115 0.0137 1
Echinococcus multilocularis geminin 0.1933 0.2729 0.2729
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0012 0.003
Schistosoma mansoni thyroid hormone receptor 0.0751 0.1043 0.1043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.005 0.0225
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0027 0.0068
Brugia malayi Cathepsin L-like cysteine proteinase 0.0071 0.0073 0.0148
Schistosoma mansoni bromodomain containing protein 0.0024 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.0054
Leishmania major endonuclease/exonuclease protein-like protein 0.0023 0.0006 0.0025
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0083 0.0091 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0086 0.0095 0.0193
Echinococcus multilocularis lamin 0.0028 0.0013 0.0013
Echinococcus granulosus cathepsin l1 0.0105 0.0123 0.0122
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0045
Toxoplasma gondii NADPH-glutathione reductase 0.0046 0.0038 0.006
Schistosoma mansoni nuclear hormone receptor 0.0086 0.0095 0.0095
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.1063 0.1488 0.1488
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0058 0.0117
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0025 0.0008 0.0153
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0023 0.0006 0.0122
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0003 0.0003
Leishmania major importin beta-1 subunit, putative 0.0024 0.0007 0.0029
Echinococcus multilocularis regulator of G protein signaling 7 0.0026 0.001 0.0009
Schistosoma mansoni inositol transporter 0.0039 0.0028 0.0028
Loa Loa (eye worm) TAR-binding protein 0.0661 0.0915 0.1859
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0115 0.0137 0.1184
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0023 0.0006 0.0122
Entamoeba histolytica G protein alpha subunit, putative 0.0046 0.0038 0.0827
Loa Loa (eye worm) hypothetical protein 0.0042 0.0032 0.0065
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0048
Brugia malayi serine/threonine-protein kinase plk-2 0.029 0.0386 0.0784
Schistosoma mansoni dep domain containing protein 0.0026 0.001 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0359 0.0484 0.1248
Schistosoma mansoni cathepsin F (C01 family) 0.0071 0.0073 0.0073
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0012 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0661 0.0915 0.0915
Schistosoma mansoni ferritin light chain 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.0032
Onchocerca volvulus Alhambra homolog 0.0239 0.0314 0.1143
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0021 0.0003 0.0003
Echinococcus granulosus flap endonuclease 1 0.0053 0.0048 0.0048
Toxoplasma gondii preprocathepsin c precursor, putative 0.44 0.6244 1
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0005 0.0009
Echinococcus multilocularis jumonji domain containing protein 0.0333 0.0447 0.0447
Trichomonas vaginalis glucosylceramidase, putative 0.0359 0.0484 0.1248
Schistosoma mansoni tar DNA-binding protein 0.0661 0.0915 0.0915
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0016 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0011 0.0028
Entamoeba histolytica deoxycytidyl transferase, putative 0.006 0.0058 0.1269
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0021 0.0085
Loa Loa (eye worm) MH1 domain-containing protein 0.0236 0.031 0.0629
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.06 0.0828 0.0827
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0023 0.0006 0.0011
Echinococcus granulosus sodium:glucose cotransporter 0.0039 0.0028 0.0028
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0069 0.014
Loa Loa (eye worm) hypothetical protein 0.1407 0.1978 0.402
Schistosoma mansoni tar DNA-binding protein 0.0661 0.0915 0.0915
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0046 0.0038 0.0076
Onchocerca volvulus 0.003 0.0015 0.0054
Trypanosoma brucei unspecified product 0.0041 0.0031 0.014
Trypanosoma brucei hypothetical protein, conserved 0.0259 0.0341 0.1543
Schistosoma mansoni hypothetical protein 0.0079 0.0086 0.0085
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0076
Brugia malayi hypothetical protein 0.0046 0.0037 0.0076
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0026 0.001 0.0201
Giardia lamblia PHD finger protein 15 0.0239 0.0314 0.0502
Brugia malayi orphan nuclear receptor NR2E1 0.0041 0.003 0.0061
Leishmania major hypothetical protein, conserved 0.0023 0.0006 0.0025
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0302 0.0402 0.1723
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0086 0.0095 0.0193
Echinococcus multilocularis lysosomal alpha glucosidase 0.0339 0.0456 0.0455
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0086 0.0095 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0058 0.0259
Onchocerca volvulus 0.0057 0.0054 0.0195
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.008 0.0206
Trypanosoma brucei DNA polymerase eta, putative 0.006 0.0058 0.0259
Echinococcus granulosus smad 0.0236 0.031 0.0309
Echinococcus granulosus tm gpcr rhodopsin 0.0633 0.0875 0.0875
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0025 0.0008 0.0028
Schistosoma mansoni apoferritin-2 0.0035 0.0022 0.0022
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0023 0.0006 0.0025
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0026 0.001 0.0079
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0046 0.0038 0.0097
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.008 0.1759
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0003 0.0007
Brugia malayi RNA recognition motif domain containing protein 0.0661 0.0915 0.1859
Brugia malayi mothers against decapentaplegic homolog 3 0.0106 0.0123 0.025
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0022 0.0045
Echinococcus granulosus FTZ F1 alpha 0.0086 0.0095 0.0095
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0053 0.0048 0.0077
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0115 0.0137 0.0619
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0259 0.0341 0.1461
Plasmodium falciparum JmjC domain-containing protein, putative 0.0077 0.0083 0.0132
Echinococcus multilocularis chromobox protein 1 0.0068 0.0069 0.0069
Echinococcus multilocularis segment polarity protein dishevelled 0.0026 0.001 0.0009
Giardia lamblia Dipeptidyl-peptidase I precursor 0.44 0.6244 1
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0047 0.0039 0.0079
Brugia malayi Sodium:solute symporter family protein 0.0039 0.0028 0.0058
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0078 0.0084 0.0379
Onchocerca volvulus 0.0046 0.0038 0.0136
Trypanosoma cruzi cysteine protease, putative 0.0054 0.005 0.0225
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0026 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0096 0.0247
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0046 0.0038 0.0322
Schistosoma mansoni ferritin 0.0035 0.0022 0.0022
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0012 0.0032
Echinococcus multilocularis synaptojanin 1 0.0023 0.0006 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.1063 0.1488 0.1488
Trichomonas vaginalis glucosylceramidase, putative 0.0359 0.0484 0.1248
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0041 0.003 0.003
Giardia lamblia Flap structure-specific endonuclease 0.0053 0.0048 0.0077
Schistosoma mansoni hypothetical protein 0.0815 0.1134 0.1134
Entamoeba histolytica hypothetical protein 0.0337 0.0452 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0091 0.0103 0.0464
Echinococcus granulosus lamin dm0 0.0028 0.0013 0.0013
Brugia malayi PHD-finger family protein 0.0047 0.0039 0.0079
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0041 0.003 0.003
Brugia malayi glutathione reductase 0.0132 0.0161 0.0327
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0046 0.0038 0.0076
Treponema pallidum exodeoxyribonuclease (exoA) 0.0115 0.0137 1
Entamoeba histolytica cysteine proteinase, putative 0.0054 0.005 0.1099
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0008 0.006
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0236 0.0309 0.0308
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0023 0.0006 0.0122
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0053 0.0048 0.0217

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.618 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.259 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.242 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.119 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.093 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.06 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.055 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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