TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 358.624 | Formula: C25H44N+
H donors: 0 H acceptors: 0 LogP: 8.14 Rotable bonds: 10
Rule of 5 violations (Lipinski): 1
SMILES: CCCCCCCCc1ccc(cc1)[C@@H]1CC[C@@H](CC1)[N+](C(C)C)(C)C
InChi: 1S/C25H44N/c1-6-7-8-9-10-11-12-22-13-15-23(16-14-22)24-17-19-25(20-18-24)26(4,5)21(2)3/h13-16,21,24-25H,6-12,17-20H2,1-5H3/q+1/t24-,25+
InChiKey: MMHMNBIZCXRPHS-PLQXJYEYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	G-protein coupled receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0061	0.0158	0.0158
Echinococcus granulosus	g protein coupled receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	isocitrate dehydrogenase	0.1538	1	1
Echinococcus multilocularis	somatostatin receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.006	0.0146	0.0146
Brugia malayi	follicle stimulating hormone receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	neuropeptide f receptor 76f	0.0061	0.0158	0.0158
Echinococcus granulosus	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Echinococcus granulosus	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Loa Loa (eye worm)	neuropeptide F receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	tm gpcr rhodopsin	0.0061	0.0158	0.0158
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.1538	1	1
Echinococcus multilocularis	neuropeptide Y receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	nephrin	0.0047	0.0064	0.0064
Loa Loa (eye worm)	neuropeptide F receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	G-protein coupled receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	neuropeptide s receptor	0.0061	0.0158	0.0158
Brugia malayi	sulfakinin receptor protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Brugia malayi	Dopamine receptor protein 2	0.0061	0.0158	0.0158
Echinococcus multilocularis	G protein coupled receptor 139	0.0061	0.0158	0.0158
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	opsin-like receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	biogenic amine 5HT receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0061	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Brugia malayi	G protein-coupled receptor F59B2.13	0.0061	0.0158	0.0158
Echinococcus multilocularis	dro:myosuppressin receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Trypanosoma brucei	isocitrate dehydrogenase, putative	0.1538	1	0.5
Echinococcus granulosus	tm gpcr rhodopsin	0.0061	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0061	0.0158	0.0158
Schistosoma mansoni	biogenic amine receptor	0.0061	0.0158	0.0158
Plasmodium vivax	isocitrate dehydrogenase [NADP], mitochondrial, putative	0.1538	1	0.5
Trypanosoma cruzi	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.1538	1	0.5
Brugia malayi	G-protein coupled receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Onchocerca volvulus	Tyrosine kinase homolog	0.0573	0.3567	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Echinococcus granulosus	G protein coupled receptor 139	0.0061	0.0158	0.0158
Trichomonas vaginalis	isocitrate dehydrogenase, putative	0.0187	0.0994	0.5
Brugia malayi	isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	0.0187	0.0994	0.0994
Echinococcus granulosus	neuropeptide receptor	0.0061	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Schistosoma mansoni	histamine h1 receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	g protein coupled receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	neuropeptide Y receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	fmrfamide receptor	0.0061	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	7TM GPCR rhodopsin	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Brugia malayi	GnHR receptor homolog	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	neuropeptide receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	neuroglian	0.0047	0.0064	0.0064
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0061	0.0158	0.0158
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	neuropeptide receptor A26	0.0061	0.0158	0.0158
Echinococcus multilocularis	sex peptide receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0061	0.0158	0.0158
Echinococcus multilocularis	isocitrate dehydrogenase (NAD) subunit	0.0187	0.0994	0.0994
Echinococcus granulosus	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Echinococcus multilocularis	neuropeptides capa receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0061	0.0158	0.0158
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0061	0.0158	0.0158
Schistosoma mansoni	Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial	0.0187	0.0994	0.0994
Echinococcus granulosus	fmrfamide receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	adenoreceptor	0.0061	0.0158	0.0158
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0061	0.0158	0.0158
Brugia malayi	Serotonin receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0061	0.0158	0.0158
Loa Loa (eye worm)	isocitrate dehydrogenase gamma subunit	0.0187	0.0994	0.0994
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Brugia malayi	RE15519p	0.0061	0.0158	0.0158
Echinococcus multilocularis	g protein coupled receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	isocitrate dehydrogenase	0.0187	0.0994	0.0994
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0061	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	dro:myosuppressin receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0061	0.0158	0.0158
Trypanosoma brucei	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.1538	1	0.5
Echinococcus granulosus	g-protein coupled receptor	0.0061	0.0158	0.0158
Brugia malayi	Serotonin receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	roundabout 2	0.006	0.0146	0.0146
Wolbachia endosymbiont of Brugia malayi	isocitrate dehydrogenase	0.0187	0.0994	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0061	0.0158	0.0158
Echinococcus granulosus	neuropeptide FF receptor 2	0.0061	0.0158	0.0158
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0061	0.0158	0.0158
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.1538	1	1
Mycobacterium tuberculosis	Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP)	0.1538	1	1
Loa Loa (eye worm)	isocitrate dehydrogenase	0.1538	1	1
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0061	0.0158	0.0158
Brugia malayi	isocitrate dehydrogenase [NAD] subunit beta, mitochondrial	0.0187	0.0994	0.0994
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0061	0.0158	0.0158
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0061	0.0158	0.0158
Schistosoma mansoni	amine GPCR	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	cell adhesion molecule	0.005	0.0082	0.0082
Echinococcus multilocularis	g protein coupled receptor	0.0061	0.0158	0.0158
Brugia malayi	Probable isocitrate dehydrogenase	0.0187	0.0994	0.0994
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0061	0.0158	0.0158
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0061	0.0158	0.0158
Schistosoma mansoni	opsin-like receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	g protein coupled receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Brugia malayi	larval opioid receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.1538	1	1
Entamoeba histolytica	tartrate dehydrogenase, putative	0.0187	0.0994	0.5
Echinococcus granulosus	neuropeptide s receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	TYRA-2 protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	neuropeptide receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	neuropeptide Y receptor	0.0061	0.0158	0.0158
Brugia malayi	Isocitrate dehydrogenase subunit gamma, mitochondrial precursor	0.0187	0.0994	0.0994
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0061	0.0158	0.0158
Echinococcus granulosus	7tm_1 domain containing protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	allatostatin A receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.006	0.0146	0.0146
Schistosoma mansoni	opsin-like receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Leishmania major	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.1538	1	1
Schistosoma mansoni	myosin xvIII	0.0061	0.0158	0.0158
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0061	0.0158	0.0158
Echinococcus granulosus	tm gpcr rhodopsin	0.0061	0.0158	0.0158
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0061	0.0158	0.0158
Loa Loa (eye worm)	melatonin receptor type 1A	0.0061	0.0158	0.0158
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0061	0.0158	0.0158
Brugia malayi	Dopamine receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	amine GPCR	0.0061	0.0158	0.0158
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0613	0.3837	0.3837
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.1538	1	1
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	neuropeptide F-like receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.005	0.0082	0.0082
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0061	0.0158	0.0158
Brugia malayi	G protein-coupled receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	neuropeptide receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	biogenic amine 5HT receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	neuropeptide receptor A26	0.0061	0.0158	0.0158
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.1538	1	1
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0061	0.0158	0.0158
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Mycobacterium leprae	PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH)	0.0187	0.0994	0.5
Schistosoma mansoni	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0061	0.0158	0.0158
Brugia malayi	Dopamine receptor protein 1	0.0061	0.0158	0.0158
Schistosoma mansoni	neuropeptide receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0061	0.0158	0.0158
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	sex peptide receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Echinococcus granulosus	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0061	0.0158	0.0158
Loa Loa (eye worm)	G-protein coupled receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	amine GPCR	0.0061	0.0158	0.0158
Echinococcus granulosus	isocitrate dehydrogenase NAD subunit	0.0187	0.0994	0.0994
Schistosoma mansoni	biogenic amine receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0061	0.0158	0.0158
Brugia malayi	Probable isocitrate dehydrogenase	0.0187	0.0994	0.0994
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Echinococcus granulosus	allatostatin A receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	orexin receptor type 2	0.0061	0.0158	0.0158
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	twitchin	0.0047	0.0064	0.0064
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0061	0.0158	0.0158
Schistosoma mansoni	amine GPCR	0.0061	0.0158	0.0158
Echinococcus granulosus	somatostatin receptor	0.0061	0.0158	0.0158
Toxoplasma gondii	isocitrate dehydrogenase	0.1538	1	0.5
Echinococcus granulosus	neuropeptides capa receptor	0.0061	0.0158	0.0158
Plasmodium falciparum	isocitrate dehydrogenase [NADP], mitochondrial	0.1538	1	0.5
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0061	0.0158	0.0158
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	orexin receptor type 2	0.0061	0.0158	0.0158
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0613	0.3837	0.3837
Brugia malayi	neuropeptide F receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	isocitrate dehydrogenase (NAD+)	0.0187	0.0994	0.0994
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	roundabout 2	0.006	0.0146	0.0146
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0061	0.0158	0.0158
Brugia malayi	neuropeptide F receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.005	0.0082	0.0082
Echinococcus multilocularis	g protein coupled receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	neuropeptide receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	serotonin receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	growth hormone secretagogue receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	isocitrate dehydrogenase NAD	0.0187	0.0994	0.0994
Brugia malayi	Isocitrate dehydrogenase	0.1538	1	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0061	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	neuropeptide receptor	0.0061	0.0158	0.0158
Onchocerca volvulus		0.056	0.348	0.9745
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0061	0.0158	0.0158
Echinococcus granulosus	rhodopsin orphan GPCR	0.0061	0.0158	0.0158
Brugia malayi	ORL1-like opioid receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	0.1538	1	1
Echinococcus granulosus	neuropeptide Y receptor	0.0061	0.0158	0.0158
Echinococcus granulosus	serotonin receptor	0.0061	0.0158	0.0158
Echinococcus multilocularis	fmrfamide receptor	0.0061	0.0158	0.0158
Brugia malayi	putative neuropeptide receptor	0.0061	0.0158	0.0158
Brugia malayi	AKH receptor	0.0061	0.0158	0.0158
Trypanosoma cruzi	isocitrate dehydrogenase, putative	0.1538	1	0.5
Schistosoma mansoni	neuropeptide F-like receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0061	0.0158	0.0158
Echinococcus granulosus	neuroglian	0.0047	0.0064	0.0064
Brugia malayi	Melatonin receptor type 1A	0.0061	0.0158	0.0158
Schistosoma mansoni	neuropeptide receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Toxoplasma gondii	isocitrate dehydrogenase	0.1538	1	0.5
Schistosoma mansoni	biogenic amine receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Brugia malayi	putative neuropeptide receptor NPR1	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	neuropeptides capa receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	serotonin receptor	0.0061	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0061	0.0158	0.0158
Mycobacterium ulcerans	3-isopropylmalate dehydrogenase	0.0187	0.0994	0.5
Echinococcus multilocularis	neuropeptides capa receptor	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0187	0.0994	0.0994
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Echinococcus multilocularis	g-protein coupled receptor	0.0061	0.0158	0.0158
Schistosoma mansoni	unc-13 (munc13)	0.0187	0.0994	0.0994
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	amine GPCR	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0158	0.0158
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0061	0.0158	0.0158

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL1962445

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1612877