Detailed information for compound 1614256

Basic information

Technical information
  • TDR Targets ID: 1614256
  • Name: 1-[4-[2-(4-chlorophenyl)ethenyl]phenyl]-2-pip eridin-1-ylethanol
  • MW: 341.874 | Formula: C21H24ClNO
  • H donors: 1 H acceptors: 1 LogP: 4.85 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(c1ccc(cc1)/C=C/c1ccc(cc1)Cl)CN1CCCCC1
  • InChi: 1S/C21H24ClNO/c22-20-12-8-18(9-13-20)5-4-17-6-10-19(11-7-17)21(24)16-23-14-2-1-3-15-23/h4-13,21,24H,1-3,14-16H2/b5-4+
  • InChiKey: QJUBRQLMPOZVNB-SNAWJCMRSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-[4-[(E)-2-(4-chlorophenyl)ethenyl]phenyl]-2-piperidin-1-ylethanol
  • 1-[4-[2-(4-chlorophenyl)vinyl]phenyl]-2-(1-piperidyl)ethanol
  • 1-[4-[(E)-2-(4-chlorophenyl)vinyl]phenyl]-2-(1-piperidyl)ethanol
  • 1-[4-[2-(4-chlorophenyl)vinyl]phenyl]-2-piperidino-ethanol
  • 1-[4-[(E)-2-(4-chlorophenyl)vinyl]phenyl]-2-piperidino-ethanol
  • 1-[4-[2-(4-chlorophenyl)ethenyl]phenyl]-2-piperidin-1-yl-ethanol
  • 1-[4-[(E)-2-(4-chlorophenyl)ethenyl]phenyl]-2-piperidin-1-yl-ethanol
  • 1-Piperidineethanol, .alpha.-[p-(p-chlorostyryl)phenyl]-
  • 1-Piperidineethanol, .alpha.[4-[2-(4-chlorophenyl)ethenyl]phenyl]-
  • NSC26040
  • NCI60_002079

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.5
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.5
Brugia malayi nuclear receptor NHR-67 0.0092 0.2314 0.369
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0195 0.627 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0092 0.2314 0.369
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Echinococcus multilocularis GPCR, family 2 0.0047 0.0574 0.0916
Brugia malayi conserved hypotetical protein 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0114 0.0181
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0195 0.627 0.627
Schistosoma mansoni hypothetical protein 0.0101 0.2656 0.2656
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.5
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.4449 0.7095
Schistosoma mansoni nuclear receptor 0.0092 0.2314 0.2314
Plasmodium falciparum thioredoxin reductase 0.0092 0.2299 1
Schistosoma mansoni nuclear hormone receptor 0.0195 0.627 0.627
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0574 0.0916
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.3241 0.5099
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0103 0.2737 0.4285
Echinococcus multilocularis thyroid hormone receptor alpha 0.0195 0.627 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0233 0.7701 1
Brugia malayi Nuclear hormone receptor E75 0.0092 0.2314 0.369
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0103 0.2737 0.2737
Trypanosoma cruzi trypanothione reductase, putative 0.0092 0.2299 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0195 0.627 0.627
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Brugia malayi jmjC domain containing protein 0.0034 0.0088 0.0141
Brugia malayi nuclear receptor NHR-88 0.0092 0.2314 0.369
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0088 0.0088
Brugia malayi hypothetical protein 0.0103 0.2737 0.4366
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0233 0.7701 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0092 0.2299 0.2985
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Loa Loa (eye worm) thioredoxin reductase 0.0092 0.2299 0.3576
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0195 0.627 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.2314 0.369
Mycobacterium tuberculosis Probable oxidoreductase 0.0233 0.7701 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0103 0.2737 0.4366
Brugia malayi hypothetical protein 0.0035 0.0114 0.0181
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.2314 0.369
Toxoplasma gondii thioredoxin reductase 0.0092 0.2299 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Schistosoma mansoni hypothetical protein 0.0047 0.0574 0.0574
Loa Loa (eye worm) hypothetical protein 0.0148 0.4449 0.7054
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0195 0.627 1
Plasmodium vivax thioredoxin reductase, putative 0.0092 0.2299 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.4449 0.7095
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Schistosoma mansoni thyroid hormone receptor 0.0195 0.627 0.627
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0209 0.6806 0.8837
Loa Loa (eye worm) hypothetical protein 0.0101 0.2656 0.4153
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0195 0.627 0.627
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0574 0.0916
Brugia malayi glutathione reductase 0.0092 0.2299 0.3666
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0195 0.627 1
Schistosoma mansoni hypothetical protein 0.0035 0.0114 0.0114
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.2314 0.369
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0092 0.2314 0.369
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.2314 0.369
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0209 0.6806 0.8837
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0092 0.2314 0.369
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0092 0.2314 0.36
Schistosoma mansoni coup transcription factor 0.0195 0.627 0.627
Loa Loa (eye worm) hypothetical protein 0.0155 0.472 0.7492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0195 0.627 1
Schistosoma mansoni RAR-like nuclear receptor 0.0195 0.627 0.627
Brugia malayi steroid hormone receptor 0.0195 0.627 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0092 0.2314 0.369
Brugia malayi ecdysone receptor 0.0092 0.2314 0.369
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0195 0.627 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0195 0.627 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.1011 0.1493
Brugia malayi nuclear hormone receptor 0.0092 0.2314 0.369
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0114 0.0181
Schistosoma mansoni zinc finger protein 0.0092 0.2314 0.2314
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Brugia malayi hypothetical protein 0.0103 0.2737 0.4366
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0574 0.0916
Loa Loa (eye worm) glutathione reductase 0.0092 0.2299 0.3576
Brugia malayi jmjC domain containing protein 0.0092 0.2318 0.3697
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0195 0.627 0.627
Brugia malayi nuclear hormone receptor family member odr-7 0.0092 0.2314 0.369
Schistosoma mansoni jumonji domain containing protein 0.0073 0.1591 0.1591
Onchocerca volvulus 0.0195 0.627 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0195 0.627 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.2656 0.4235
Echinococcus multilocularis ecdysone induced protein 78C 0.0195 0.627 1
Brugia malayi hypothetical protein 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0574 0.0786
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0195 0.627 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0195 0.627 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Schistosoma mansoni thyroid hormone receptor 0.0195 0.627 0.627
Onchocerca volvulus Bile acid receptor homolog 0.0195 0.627 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0195 0.627 1
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.0088 0.0141
Echinococcus granulosus GPCR family 2 0.0047 0.0574 0.0916
Mycobacterium tuberculosis Probable dehydrogenase 0.0209 0.6806 0.8837
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0195 0.627 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0092 0.2314 0.2314
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Brugia malayi hypothetical protein 0.0155 0.472 0.7527
Leishmania major trypanothione reductase 0.0092 0.2299 1
Plasmodium vivax glutathione reductase, putative 0.0092 0.2299 1
Schistosoma mansoni retinoic acid receptor RXR 0.0195 0.627 0.627
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0092 0.2314 0.2314
Echinococcus granulosus nuclear receptor nhr 48 0.0092 0.2314 0.369
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0195 0.627 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0574 0.0786
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0209 0.6806 0.8837
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.3241 0.5099
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0195 0.627 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0088 0.0141
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.2318 0.3697
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0195 0.627 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0103 0.2737 0.2737
Echinococcus multilocularis FTZ F1 alpha 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0195 0.627 1
Schistosoma mansoni nuclear receptor 0.0092 0.2314 0.2314
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0088 0.0088
Mycobacterium tuberculosis Probable reductase 0.0209 0.6806 0.8837
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.4449 0.7054
Brugia malayi orphan nuclear receptor NR2E1 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.2318 0.3697
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0195 0.627 1
Loa Loa (eye worm) DR-78 0.0092 0.2314 0.36
Brugia malayi nuclear receptor RXR 0.0103 0.2737 0.4366
Schistosoma mansoni nuclear hormone receptor 0.0092 0.2314 0.2314
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.5
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.2737 0.4366
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0092 0.2299 0.3666
Schistosoma mansoni hypothetical protein 0.0047 0.0574 0.0574
Brugia malayi nuclear hormone receptor family member nhr-6 0.0092 0.2314 0.369
Brugia malayi ecdysteroid receptor 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Brugia malayi Steroid receptor seven-up type 2 0.0195 0.627 1
Brugia malayi MH2 domain containing protein 0.0116 0.3241 0.5168
Echinococcus multilocularis thioredoxin glutathione reductase 0.0092 0.2299 0.3666
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0195 0.627 1
Onchocerca volvulus 0.0155 0.472 0.608
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0195 0.627 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0103 0.2737 0.4366
Plasmodium falciparum glutathione reductase 0.0092 0.2299 1
Echinococcus granulosus ecdysone induced protein 78C 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0195 0.627 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0574 0.0916
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.2737 0.4366
Schistosoma mansoni nuclear receptor nhr-48 0.0092 0.2314 0.2314
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0284 0.0453
Schistosoma mansoni nuclear hormone receptor 0.0092 0.2314 0.2314
Echinococcus granulosus FTZ F1 alpha 0.0195 0.627 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0092 0.2314 0.36
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0195 0.627 0.627
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0574 0.0916
Brugia malayi Nuclear hormone receptor E75 0.0092 0.2314 0.369
Brugia malayi nuclear receptor RXR 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0048 0.0632 0.088
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0209 0.6806 0.8837
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0574 0.0916
Brugia malayi Thioredoxin reductase 0.0092 0.2299 0.3666
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0195 0.627 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0195 0.627 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0233 0.7701 1
Loa Loa (eye worm) nuclear hormone receptor 0.0092 0.2314 0.36
Brugia malayi Nuclear hormone receptor-like 1 0.0195 0.627 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0195 0.627 0.627
Trypanosoma brucei trypanothione reductase 0.0092 0.2299 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0195 0.627 1
Schistosoma mansoni hypothetical protein 0.0047 0.0574 0.0574
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0195 0.627 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0195 0.627 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0195 0.627 1
Brugia malayi nuclear hormone receptor 0.0195 0.627 1
Brugia malayi hypothetical protein 0.0092 0.2314 0.369
Brugia malayi tailless protein 0.0092 0.2314 0.369
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0195 0.627 1
Schistosoma mansoni hypothetical protein 0.0047 0.0574 0.0574
Loa Loa (eye worm) steroid hormone receptor 0.0195 0.627 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0092 0.2314 0.369
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0195 0.627 0.627
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Brugia malayi nuclear receptor NHR-88 0.0195 0.627 1
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0284 0.0453
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0195 0.627 1

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -5.212 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.652 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.361 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.298 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.296 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.245 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.22 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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