Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.0275 | 0.0397 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0139 | 0.062 | 0.062 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0092 | 0.0337 | 0.0337 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0226 | 0.1132 | 0.1132 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0062 | 0.0164 | 0.1556 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0092 | 0.0337 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0032 | 0.0032 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0037 | 0.0013 | 0.0013 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0066 | 0.0066 |
Schistosoma mansoni | tyrosine kinase | 0.0037 | 0.0013 | 0.0013 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0201 | 0.0987 | 0.0987 |
Onchocerca volvulus | 0.0046 | 0.0066 | 0.0077 | |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Schistosoma mansoni | tyrosine kinase | 0.0037 | 0.0013 | 0.0013 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0065 | 0.0183 | 0.0183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0092 | 0.0337 | 0.0337 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.038 | 0.2047 | 0.2047 |
Onchocerca volvulus | 0.0046 | 0.0066 | 0.0077 | |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.038 | 0.2047 | 0.2598 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0249 | 0.1273 | 0.1273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.1722 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.0062 | 0.0164 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0095 | 0.0095 |
Schistosoma mansoni | tyrosine kinase | 0.0316 | 0.1665 | 0.1665 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Schistosoma mansoni | tyrosine kinase | 0.0316 | 0.1665 | 0.1665 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | thyroid hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.038 | 0.2047 | 0.2788 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0092 | 0.0337 | 0.0443 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0121 | 0.0512 | 0.0515 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0226 | 0.1132 | 0.1132 |
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.0275 | 0.0397 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0061 | 0.0153 | 0.0153 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0082 | 0.0278 | 0.0278 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0526 | 0.2912 | 0.2912 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0139 | 0.062 | 0.0854 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.004 | 0.0032 | 0.0046 |
Trypanosoma cruzi | cysteine protease, putative | 0.0062 | 0.0164 | 0.0192 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0092 | 0.0337 | 0.0573 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.062 | 0.062 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Echinococcus multilocularis | cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0121 | 0.0512 | 0.0512 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | enteropeptidase | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0973 | 0.5561 | 0.5561 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0037 | 0.0013 | 0.0013 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0065 | 0.0183 | 0.0265 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0092 | 0.0337 | 0.0256 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0065 | 0.0183 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0337 | 0.0337 |
Schistosoma mansoni | tyrosine kinase | 0.0514 | 0.2839 | 0.2839 |
Onchocerca volvulus | 0.0092 | 0.0337 | 0.047 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0121 | 0.0512 | 0.0697 |
Brugia malayi | TATA binding protein associated factor | 0.0092 | 0.0337 | 0.0487 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.038 | 0.2047 | 0.2598 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0139 | 0.062 | 0.062 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0249 | 0.1273 | 0.1273 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 0.1797 | 0.1797 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0037 | 0.0013 | 0.0013 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Schistosoma mansoni | nuclear hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0121 | 0.0512 | 0.0512 |
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.0153 | 0.0153 |
Echinococcus multilocularis | aminopeptidase N | 0.0092 | 0.0337 | 0.0337 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0065 | 0.0183 | 0.0265 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0092 | 0.0337 | 0.0337 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0572 | 0.3184 | 0.4577 |
Plasmodium vivax | vivapain-2 | 0.0121 | 0.0512 | 0.0697 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0062 | 0.0164 | 0.0237 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0226 | 0.1132 | 0.1132 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 0.1797 | 0.1797 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.038 | 0.2047 | 0.2926 |
Brugia malayi | nuclear hormone receptor | 0.0065 | 0.0183 | 0.0265 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0213 | 0.1059 | 0.1059 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.038 | 0.2047 | 0.2926 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0062 | 0.0164 | 0.0164 |
Brugia malayi | hypothetical protein | 0.0082 | 0.0278 | 0.0402 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Brugia malayi | hypothetical protein | 0.0572 | 0.3184 | 0.4602 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0275 | 0.0275 |
Echinococcus granulosus | aminopeptidase N | 0.0092 | 0.0337 | 0.0337 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | TK protein kinase | 0.0226 | 0.1132 | 0.1132 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | Trypsin family protein | 0.0338 | 0.1797 | 0.2598 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0065 | 0.0183 | 0.0265 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0201 | 0.0987 | 0.0987 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0032 | 0.0032 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0037 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.004 | 0.0032 | 0.0032 |
Brugia malayi | Trypsin family protein | 0.0082 | 0.0278 | 0.0402 |
Echinococcus multilocularis | cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0275 | 0.0275 |
Echinococcus multilocularis | Mastin | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Onchocerca volvulus | Cathepsin L homolog | 0.0121 | 0.0512 | 0.0723 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0065 | 0.0183 | 0.0247 |
Brugia malayi | Variant SH3 domain containing protein | 0.0048 | 0.008 | 0.0116 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus granulosus | c src tyrosine kinase | 0.0061 | 0.0153 | 0.0153 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0065 | 0.0183 | 0.0265 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0121 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0092 | 0.0337 | 0.0337 |
Brugia malayi | Trypsin family protein | 0.0082 | 0.0278 | 0.0402 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0081 | 0.0275 | 0.0353 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Echinococcus granulosus | cathepsin l1 | 0.0081 | 0.0275 | 0.0275 |
Onchocerca volvulus | Cathepsin F homolog | 0.0121 | 0.0512 | 0.0723 |
Leishmania major | hypothetical protein, conserved | 0.0139 | 0.062 | 0.043 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0065 | 0.0183 | 0.0183 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0121 | 0.0512 | 0.0515 |
Brugia malayi | ecdysteroid receptor | 0.0065 | 0.0183 | 0.0265 |
Brugia malayi | Peptidase family M1 containing protein | 0.0092 | 0.0337 | 0.0487 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0092 | 0.0337 | 0.0256 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0316 | 0.1665 | 0.1665 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.062 | 0.062 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0973 | 0.5561 | 0.8039 |
Trypanosoma brucei | aminopeptidase, putative | 0.0092 | 0.0337 | 0.0256 |
Brugia malayi | hypothetical protein | 0.0092 | 0.0337 | 0.0487 |
Loa Loa (eye worm) | fibroinase | 0.0121 | 0.0512 | 0.0512 |
Echinococcus granulosus | tyrosine kinase | 0.0037 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.0338 | 0.1797 | 0.2585 | |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0082 | 0.0278 | 0.0278 |
Brugia malayi | Peptidase family M1 containing protein | 0.0092 | 0.0337 | 0.0487 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0065 | 0.0183 | 0.0247 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Onchocerca volvulus | 0.0256 | 0.1314 | 0.1885 | |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Leishmania major | cysteine peptidase A (CPA) | 0.0121 | 0.0512 | 0.0265 |
Brugia malayi | steroid hormone receptor | 0.0065 | 0.0183 | 0.0265 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0337 | 0.0337 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0048 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.004 | 0.0032 | 0.0046 |
Echinococcus granulosus | thymidylate synthase | 0.1202 | 0.6918 | 0.6918 |
Loa Loa (eye worm) | thymidylate synthase | 0.1202 | 0.6918 | 0.6918 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0062 | 0.0164 | 0.0164 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0121 | 0.0512 | 0.0512 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0152 | 0.0693 | 0.0693 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Echinococcus granulosus | tyrosine kinase | 0.0226 | 0.1132 | 0.1132 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus granulosus | NCK adaptor protein | 0.0048 | 0.008 | 0.008 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0092 | 0.0337 | 0.0443 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0065 | 0.0183 | 0.0265 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0121 | 0.0512 | 0.074 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.038 | 0.2047 | 0.2598 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0065 | 0.0183 | 0.0265 |
Onchocerca volvulus | 0.0046 | 0.0066 | 0.0077 | |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Loa Loa (eye worm) | aminopeptidase N | 0.0092 | 0.0337 | 0.0337 |
Echinococcus granulosus | cathepsin l1 | 0.0121 | 0.0512 | 0.0512 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0036 | 0.0009 | 0.0009 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0048 | 0.008 | 0.008 |
Schistosoma mansoni | tyrosine kinase | 0.0249 | 0.1273 | 0.1273 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0572 | 0.3184 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Plasmodium vivax | vivapain-1 | 0.0062 | 0.0164 | 0.0192 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0164 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0061 | 0.0153 | 0.0153 |
Echinococcus multilocularis | 0.0299 | 0.1567 | 0.1567 | |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Schistosoma mansoni | tyrosine kinase | 0.0973 | 0.5561 | 0.5561 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.035 | 0.1869 | 0.1869 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0249 | 0.1273 | 0.1273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Schistosoma mansoni | tyrosine kinase | 0.0514 | 0.2839 | 0.2839 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0338 | 0.1797 | 0.1797 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0065 | 0.0183 | 0.0183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0139 | 0.062 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0337 | 0.0337 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0062 | 0.0164 | 0.0164 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0092 | 0.0337 | 0.0443 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0275 | 0.0275 |
Schistosoma mansoni | cathepsin s | 0.004 | 0.0032 | 0.0032 |
Echinococcus granulosus | mitogen activated protein kinase | 0.038 | 0.2047 | 0.2047 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0121 | 0.0512 | 0.0697 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | serine/threonine protein kinase | 0.038 | 0.2047 | 0.2047 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0065 | 0.0183 | 0.0183 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0092 | 0.0337 | 0.0443 |
Brugia malayi | MAP kinase sur-1 | 0.038 | 0.2047 | 0.2959 |
Onchocerca volvulus | 0.0051 | 0.0095 | 0.012 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Schistosoma mansoni | adapter molecule crk | 0.0048 | 0.008 | 0.008 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0249 | 0.1273 | 0.1273 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0139 | 0.062 | 0.0854 |
Schistosoma mansoni | tyrosine kinase | 0.0249 | 0.1273 | 0.1273 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0065 | 0.0183 | 0.0247 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0226 | 0.1132 | 0.1132 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0213 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0013 | 0.0013 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0092 | 0.0337 | 0.0256 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0249 | 0.1273 | 0.1273 |
Plasmodium vivax | unspecified product | 0.0062 | 0.0164 | 0.0192 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0048 | 0.008 | 0.0116 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0121 | 0.0512 | 0.0697 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.0032 | 0.0046 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0092 | 0.0337 | 0.0443 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.1202 | 0.6918 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.038 | 0.2047 | 0.2047 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0092 | 0.0337 | 0.0089 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0092 | 0.0337 | 0.0443 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | cysteine protease | 0.0062 | 0.0164 | 0.0164 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0249 | 0.1273 | 0.1273 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0048 | 0.008 | 0.008 |
Brugia malayi | hypothetical protein | 0.0092 | 0.0337 | 0.0487 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0065 | 0.0183 | 0.0265 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.0512 | 0.5121 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | TK protein kinase | 0.0201 | 0.0987 | 0.0987 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0061 | 0.0153 | 0.0222 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0065 | 0.0183 | 0.0183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Giardia lamblia | Kinase, CMGC MAPK | 0.038 | 0.2047 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 0.6918 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0066 | 0.0066 |
Trichomonas vaginalis | CMGC family protein kinase | 0.038 | 0.2047 | 0.6235 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0061 | 0.0153 | 0.0153 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Toxoplasma gondii | cathepsin CPL | 0.0121 | 0.0512 | 0.0265 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.0153 | 0.0153 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.1556 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Brugia malayi | cathepsin L-like precursor | 0.0081 | 0.0275 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0121 | 0.0512 | 0.0697 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0081 | 0.0275 | 0.0275 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0526 | 0.2912 | 0.2912 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0121 | 0.0512 | 0.0512 |
Echinococcus granulosus | Mastin | 0.0082 | 0.0278 | 0.0278 |
Brugia malayi | SEA domain containing protein | 0.0046 | 0.0066 | 0.0095 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0037 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0048 | 0.008 | 0.008 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0121 | 0.0512 | 0.5121 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0092 | 0.0337 | 0.0337 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0037 | 0.0013 | 0.0013 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0065 | 0.0183 | 0.0265 |
Brugia malayi | Kringle domain containing protein | 0.0139 | 0.062 | 0.0896 |
Onchocerca volvulus | 0.0065 | 0.0183 | 0.0247 | |
Schistosoma mansoni | tyrosine kinase | 0.0514 | 0.2839 | 0.2839 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0065 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.0081 | 0.0275 | 0.038 | |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.038 | 0.2047 | 0.2047 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0092 | 0.0337 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.008 | 0.008 |
Brugia malayi | protein-tyrosine kinase | 0.0226 | 0.1132 | 0.1636 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | DOMON domain-containing protein | 0.0046 | 0.0066 | 0.0066 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0249 | 0.1273 | 0.1273 |
Echinococcus granulosus | enteropeptidase | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | SRC-1 | 0.0249 | 0.1273 | 0.1273 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0065 | 0.0183 | 0.0265 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.1722 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Trichomonas vaginalis | CMGC family protein kinase | 0.038 | 0.2047 | 0.6235 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Onchocerca volvulus | Cathepsin L homolog | 0.0121 | 0.0512 | 0.0723 |
Schistosoma mansoni | nck2/grb4 | 0.0048 | 0.008 | 0.008 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.0275 | 0.0366 |
Echinococcus granulosus | cathepsin L | 0.0062 | 0.0164 | 0.0164 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0048 | 0.008 | 0.008 |
Entamoeba histolytica | protein kinase, putative | 0.0201 | 0.0987 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | Protein kinase domain containing protein | 0.0316 | 0.1665 | 0.2407 |
Brugia malayi | SRC-1 | 0.0249 | 0.1273 | 0.184 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0065 | 0.0183 | 0.0183 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0062 | 0.0164 | 0.0192 |
Loa Loa (eye worm) | trypsin family protein | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0173 | 0.0821 | 0.0821 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0092 | 0.0337 | 0.0443 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0121 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0032 | 0.0032 |
Echinococcus multilocularis | NCK adaptor protein | 0.0048 | 0.008 | 0.008 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0065 | 0.0183 | 0.0183 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0249 | 0.1273 | 0.1273 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0512 | 0.0512 |
Echinococcus multilocularis | cathepsin L | 0.0062 | 0.0164 | 0.0164 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | tyrosine kinase | 0.0526 | 0.2912 | 0.2912 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Brugia malayi | hypothetical protein | 0.0792 | 0.4487 | 0.6486 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0092 | 0.0337 | 0.0573 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0037 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | insulin receptor | 0.0316 | 0.1665 | 0.1665 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0085 | 0.0301 | 0.0301 |
Schistosoma mansoni | thyroid hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Trichomonas vaginalis | CMGC family protein kinase | 0.038 | 0.2047 | 0.6235 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0973 | 0.5561 | 0.5561 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0065 | 0.0183 | 0.0265 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0081 | 0.0275 | 0.0397 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0092 | 0.0337 | 0.0443 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | nuclear receptor NHR-88 | 0.0065 | 0.0183 | 0.0265 |
Entamoeba histolytica | aminopeptidase, putative | 0.0092 | 0.0337 | 0.333 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0065 | 0.0183 | 0.0265 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0062 | 0.0164 | 0.0164 |
Mycobacterium ulcerans | thymidylate synthase | 0.1202 | 0.6918 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0062 | 0.0164 | 0.0237 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0121 | 0.0512 | 0.0512 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0092 | 0.0337 | 0.0256 |
Brugia malayi | Trypsin family protein | 0.0082 | 0.0278 | 0.0402 |
Schistosoma mansoni | coup transcription factor | 0.0065 | 0.0183 | 0.0183 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0226 | 0.1132 | 0.1132 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0065 | 0.0183 | 0.0183 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0092 | 0.0337 | 0.0337 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Onchocerca volvulus | 0.0046 | 0.0066 | 0.0077 | |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0092 | 0.0337 | 0.0256 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0065 | 0.0183 | 0.0183 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0121 | 0.0512 | 0.0515 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Brugia malayi | Peptidase family M1 containing protein | 0.0092 | 0.0337 | 0.0487 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Brugia malayi | thymidylate synthase | 0.1202 | 0.6918 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0065 | 0.0183 | 0.0265 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0121 | 0.0512 | 0.0512 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0062 | 0.0164 | 0.1556 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0065 | 0.0183 | 0.0265 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0973 | 0.5561 | 0.5561 |
Echinococcus granulosus | FTZ F1 alpha | 0.0065 | 0.0183 | 0.0183 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Brugia malayi | Protein kinase domain containing protein | 0.0152 | 0.0693 | 0.1002 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0253 | 0.1293 | 0.1293 |
Onchocerca volvulus | 0.0092 | 0.0337 | 0.047 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Brugia malayi | Trypsin-like protease protein 5 | 0.0082 | 0.0278 | 0.0402 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0065 | 0.0183 | 0.0183 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0013 | 0.0018 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0065 | 0.0183 | 0.0265 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0082 | 0.0278 | 0.0278 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0092 | 0.0337 | 0.0443 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Loa Loa (eye worm) | ctsf protein | 0.0121 | 0.0512 | 0.0512 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0249 | 0.1273 | 0.1273 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0061 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.038 | 0.2047 | 0.2926 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0037 | 0.0013 | 0.0013 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0121 | 0.0512 | 0.0697 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Onchocerca volvulus | 0.0092 | 0.0337 | 0.047 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Trichomonas vaginalis | CMGC family protein kinase | 0.038 | 0.2047 | 0.6235 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0081 | 0.0275 | 0.269 |
Echinococcus granulosus | insulin receptor | 0.0316 | 0.1665 | 0.1665 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Plasmodium vivax | vivapain-2 | 0.0121 | 0.0512 | 0.0697 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0082 | 0.0278 | 0.0402 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.038 | 0.2047 | 0.2926 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Echinococcus multilocularis | tyrosine kinase | 0.0037 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0316 | 0.1665 | 0.1665 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0526 | 0.2912 | 0.2912 |
Toxoplasma gondii | kringle domain-containing protein | 0.0139 | 0.062 | 0.043 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0048 | 0.008 | 0.008 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.1722 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0249 | 0.1273 | 0.1273 |
Schistosoma mansoni | tyrosine kinase | 0.0526 | 0.2912 | 0.2912 |
Echinococcus multilocularis | thymidylate synthase | 0.1202 | 0.6918 | 0.6918 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0048 | 0.008 | 0.008 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.1202 | 0.6918 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0316 | 0.1665 | 0.1665 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0121 | 0.0512 | 0.5121 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0061 | 0.0153 | 0.0153 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.1202 | 0.6918 | 1 |
Brugia malayi | Variant SH3 domain containing protein | 0.0048 | 0.008 | 0.0116 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.0192 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.0275 | 0.0366 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0092 | 0.0337 | 0.0573 |
Onchocerca volvulus | 0.0139 | 0.062 | 0.088 | |
Trypanosoma brucei | protein kinase, putative | 0.038 | 0.2047 | 0.2788 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0065 | 0.0183 | 0.0265 |
Brugia malayi | Muscle positioning protein 4 | 0.0051 | 0.0095 | 0.0138 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.038 | 0.2047 | 0.2047 |
Onchocerca volvulus | 0.1202 | 0.6918 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 ratio (binding) | Transcriptional activation of retinoic acid RAR-alpha receptor; Not active | ChEMBL. | No reference | |
EC50 ratio (binding) | = 20 | Transcriptional activation of retinoic acid RAR-gamma receptor | ChEMBL. | No reference |
EC50 ratio (binding) | = 100 | Transcriptional activation of retinoic acid RAR-beta receptor | ChEMBL. | No reference |
EC50 ratio (binding) | 0 | Transcriptional activation of retinoic acid RAR-alpha receptor; Not active | ChEMBL. | No reference |
EC50 ratio (binding) | = 20 | Transcriptional activation of retinoic acid RAR-gamma receptor | ChEMBL. | No reference |
EC50 ratio (binding) | = 100 | Transcriptional activation of retinoic acid RAR-beta receptor | ChEMBL. | No reference |
ED30 (functional) | mM | Concentration of the compound that induces 30% utriculi reduction in rhino mouse.; Not determined | ChEMBL. | No reference |
ED30 (functional) | 0 mM | Concentration of the compound that induces 30% utriculi reduction in rhino mouse.; Not determined | ChEMBL. | No reference |
Max (functional) | = 0 % | Maximal transcriptional activation of RAR-alpha relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 0 % | Maximal transcriptional activation of RAR-alpha relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 41 % | Maximal trascriptional activation of RAR-beta relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 41 % | Maximal trascriptional activation of RAR-beta relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 46 % | Maximal trascriptional activation of RAR-gamma relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 46 % | Maximal trascriptional activation of RAR-gamma relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.