Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0061 | 0.0153 | 0.0153 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0082 | 0.0278 | 0.0278 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0526 | 0.2912 | 0.2912 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0139 | 0.062 | 0.0854 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.0275 | 0.0397 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0121 | 0.0512 | 0.0515 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0092 | 0.0337 | 0.0443 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0226 | 0.1132 | 0.1132 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0082 | 0.0278 | 0.0278 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.038 | 0.2047 | 0.2788 |
Schistosoma mansoni | thyroid hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0121 | 0.0512 | 0.0512 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Echinococcus multilocularis | cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0092 | 0.0337 | 0.0573 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.062 | 0.062 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.004 | 0.0032 | 0.0046 |
Trypanosoma cruzi | cysteine protease, putative | 0.0062 | 0.0164 | 0.0192 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0201 | 0.0987 | 0.0987 |
Onchocerca volvulus | 0.0046 | 0.0066 | 0.0077 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Schistosoma mansoni | tyrosine kinase | 0.0037 | 0.0013 | 0.0013 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0065 | 0.0183 | 0.0183 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0037 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0032 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0066 | 0.0066 |
Schistosoma mansoni | tyrosine kinase | 0.0037 | 0.0013 | 0.0013 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.1556 |
Brugia malayi | Cathepsin L-like precursor | 0.0081 | 0.0275 | 0.0397 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0139 | 0.062 | 0.062 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0092 | 0.0337 | 0.0337 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0226 | 0.1132 | 0.1132 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0092 | 0.0337 | 0.0089 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0062 | 0.0164 | 0.1556 |
Schistosoma mansoni | tyrosine kinase | 0.0316 | 0.1665 | 0.1665 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | tyrosine kinase | 0.0316 | 0.1665 | 0.1665 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0249 | 0.1273 | 0.1273 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.1722 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0095 | 0.0095 |
Plasmodium vivax | vivapain-3 | 0.0062 | 0.0164 | 0.0192 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.038 | 0.2047 | 0.2047 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0092 | 0.0337 | 0.0337 |
Onchocerca volvulus | 0.0046 | 0.0066 | 0.0077 | |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.038 | 0.2047 | 0.2598 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | aminopeptidase N | 0.0092 | 0.0337 | 0.0337 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | hypothetical protein | 0.0082 | 0.0278 | 0.0402 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Brugia malayi | hypothetical protein | 0.0572 | 0.3184 | 0.4602 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0275 | 0.0275 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0062 | 0.0164 | 0.0164 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0213 | 0.1059 | 0.1059 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.038 | 0.2047 | 0.2926 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0275 | 0.0275 |
Echinococcus multilocularis | Mastin | 0.0082 | 0.0278 | 0.0278 |
Onchocerca volvulus | Cathepsin L homolog | 0.0121 | 0.0512 | 0.0723 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.004 | 0.0032 | 0.0032 |
Brugia malayi | Trypsin family protein | 0.0082 | 0.0278 | 0.0402 |
Echinococcus multilocularis | cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0032 | 0.0032 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0037 | 0.0013 | 0.0013 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | TK protein kinase | 0.0226 | 0.1132 | 0.1132 |
Brugia malayi | Trypsin family protein | 0.0338 | 0.1797 | 0.2598 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0201 | 0.0987 | 0.0987 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0065 | 0.0183 | 0.0265 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0121 | 0.0512 | 0.0697 |
Brugia malayi | TATA binding protein associated factor | 0.0092 | 0.0337 | 0.0487 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.038 | 0.2047 | 0.2598 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0337 | 0.0337 |
Schistosoma mansoni | tyrosine kinase | 0.0514 | 0.2839 | 0.2839 |
Onchocerca volvulus | 0.0092 | 0.0337 | 0.047 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0065 | 0.0183 | 0.0265 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0092 | 0.0337 | 0.0256 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0065 | 0.0183 | 0.0265 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus multilocularis | enteropeptidase | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0037 | 0.0013 | 0.0013 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0973 | 0.5561 | 0.5561 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 0.1797 | 0.1797 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.038 | 0.2047 | 0.2926 |
Brugia malayi | nuclear hormone receptor | 0.0065 | 0.0183 | 0.0265 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0092 | 0.0337 | 0.0337 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0226 | 0.1132 | 0.1132 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0062 | 0.0164 | 0.0237 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0572 | 0.3184 | 0.4577 |
Plasmodium vivax | vivapain-2 | 0.0121 | 0.0512 | 0.0697 |
Loa Loa (eye worm) | cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0121 | 0.0512 | 0.0512 |
Echinococcus multilocularis | aminopeptidase N | 0.0092 | 0.0337 | 0.0337 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.0153 | 0.0153 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0065 | 0.0183 | 0.0265 |
Brugia malayi | SH2 domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0139 | 0.062 | 0.062 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0249 | 0.1273 | 0.1273 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0037 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 0.1797 | 0.1797 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | steroid hormone receptor | 0.0065 | 0.0183 | 0.0265 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Leishmania major | cysteine peptidase A (CPA) | 0.0121 | 0.0512 | 0.0265 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0065 | 0.0183 | 0.0247 |
Brugia malayi | Peptidase family M1 containing protein | 0.0092 | 0.0337 | 0.0487 |
Onchocerca volvulus | 0.0256 | 0.1314 | 0.1885 | |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Brugia malayi | hypothetical protein | 0.0092 | 0.0337 | 0.0487 |
Loa Loa (eye worm) | fibroinase | 0.0121 | 0.0512 | 0.0512 |
Echinococcus granulosus | tyrosine kinase | 0.0037 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.0338 | 0.1797 | 0.2585 | |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0082 | 0.0278 | 0.0278 |
Echinococcus granulosus | tyrosine kinase | 0.0226 | 0.1132 | 0.1132 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus granulosus | NCK adaptor protein | 0.0048 | 0.008 | 0.008 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0092 | 0.0337 | 0.0443 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0065 | 0.0183 | 0.0265 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0121 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0152 | 0.0693 | 0.0693 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0065 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.004 | 0.0032 | 0.0046 |
Echinococcus granulosus | thymidylate synthase | 0.1202 | 0.6918 | 0.6918 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0062 | 0.0164 | 0.0164 |
Loa Loa (eye worm) | thymidylate synthase | 0.1202 | 0.6918 | 0.6918 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0337 | 0.0337 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0048 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0081 | 0.0275 | 0.0353 |
Echinococcus granulosus | cathepsin l1 | 0.0081 | 0.0275 | 0.0275 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Onchocerca volvulus | Cathepsin F homolog | 0.0121 | 0.0512 | 0.0723 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0092 | 0.0337 | 0.0337 |
Brugia malayi | Trypsin family protein | 0.0082 | 0.0278 | 0.0402 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0121 | 0.0512 | 0.0512 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0065 | 0.0183 | 0.0247 |
Brugia malayi | Variant SH3 domain containing protein | 0.0048 | 0.008 | 0.0116 |
Echinococcus granulosus | c src tyrosine kinase | 0.0061 | 0.0153 | 0.0153 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0065 | 0.0183 | 0.0265 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0973 | 0.5561 | 0.8039 |
Trypanosoma brucei | aminopeptidase, putative | 0.0092 | 0.0337 | 0.0256 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0092 | 0.0337 | 0.0256 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0316 | 0.1665 | 0.1665 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.062 | 0.062 |
Brugia malayi | Peptidase family M1 containing protein | 0.0092 | 0.0337 | 0.0487 |
Leishmania major | hypothetical protein, conserved | 0.0139 | 0.062 | 0.043 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0065 | 0.0183 | 0.0183 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0121 | 0.0512 | 0.0515 |
Brugia malayi | ecdysteroid receptor | 0.0065 | 0.0183 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0337 | 0.0337 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0062 | 0.0164 | 0.0164 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0092 | 0.0337 | 0.0443 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0065 | 0.0183 | 0.0183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0139 | 0.062 | 0.0675 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Schistosoma mansoni | tyrosine kinase | 0.0514 | 0.2839 | 0.2839 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0338 | 0.1797 | 0.1797 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Schistosoma mansoni | adapter molecule crk | 0.0048 | 0.008 | 0.008 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Onchocerca volvulus | 0.0051 | 0.0095 | 0.012 | |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Schistosoma mansoni | serine/threonine protein kinase | 0.038 | 0.2047 | 0.2047 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | MAP kinase sur-1 | 0.038 | 0.2047 | 0.2959 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0092 | 0.0337 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0275 | 0.0275 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.0192 |
Schistosoma mansoni | cathepsin s | 0.004 | 0.0032 | 0.0032 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0121 | 0.0512 | 0.0697 |
Echinococcus granulosus | mitogen activated protein kinase | 0.038 | 0.2047 | 0.2047 |
Echinococcus granulosus | cathepsin l1 | 0.0121 | 0.0512 | 0.0512 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0036 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0048 | 0.008 | 0.008 |
Schistosoma mansoni | tyrosine kinase | 0.0249 | 0.1273 | 0.1273 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Loa Loa (eye worm) | aminopeptidase N | 0.0092 | 0.0337 | 0.0337 |
Onchocerca volvulus | 0.0046 | 0.0066 | 0.0077 | |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0121 | 0.0512 | 0.074 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.038 | 0.2047 | 0.2598 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0065 | 0.0183 | 0.0265 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0249 | 0.1273 | 0.1273 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.035 | 0.1869 | 0.1869 |
Schistosoma mansoni | tyrosine kinase | 0.0973 | 0.5561 | 0.5561 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0061 | 0.0153 | 0.0153 |
Echinococcus multilocularis | 0.0299 | 0.1567 | 0.1567 | |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Plasmodium vivax | vivapain-1 | 0.0062 | 0.0164 | 0.0192 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0164 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0572 | 0.3184 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0082 | 0.0278 | 0.0278 |
Entamoeba histolytica | cysteine protease, putative | 0.0121 | 0.0512 | 0.5121 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0065 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Loa Loa (eye worm) | TK protein kinase | 0.0201 | 0.0987 | 0.0987 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0061 | 0.0153 | 0.0222 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0065 | 0.0183 | 0.0183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Brugia malayi | hypothetical protein | 0.0092 | 0.0337 | 0.0487 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0065 | 0.0183 | 0.0265 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0249 | 0.1273 | 0.1273 |
Echinococcus granulosus | cysteine protease | 0.0062 | 0.0164 | 0.0164 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0048 | 0.008 | 0.008 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.038 | 0.2047 | 0.2047 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0092 | 0.0337 | 0.0089 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0092 | 0.0337 | 0.0443 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.1556 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Trichomonas vaginalis | CMGC family protein kinase | 0.038 | 0.2047 | 0.6235 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0061 | 0.0153 | 0.0153 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Toxoplasma gondii | cathepsin CPL | 0.0121 | 0.0512 | 0.0265 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | tyrosine kinase | 0.0061 | 0.0153 | 0.0153 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 0.6918 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0066 | 0.0066 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Giardia lamblia | Kinase, CMGC MAPK | 0.038 | 0.2047 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0013 | 0.0013 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0065 | 0.0183 | 0.0247 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0226 | 0.1132 | 0.1132 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0213 | 0.1059 | 0.1059 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0249 | 0.1273 | 0.1273 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0139 | 0.062 | 0.0854 |
Schistosoma mansoni | tyrosine kinase | 0.0249 | 0.1273 | 0.1273 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0092 | 0.0337 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.1202 | 0.6918 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0121 | 0.0512 | 0.0697 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0048 | 0.008 | 0.0116 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.0032 | 0.0046 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0249 | 0.1273 | 0.1273 |
Plasmodium vivax | unspecified product | 0.0062 | 0.0164 | 0.0192 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0092 | 0.0337 | 0.0256 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0065 | 0.0183 | 0.0183 |
Echinococcus granulosus | enteropeptidase | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | SRC-1 | 0.0249 | 0.1273 | 0.1273 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0065 | 0.0183 | 0.0183 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0065 | 0.0183 | 0.0265 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0249 | 0.1273 | 0.1273 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.008 | 0.008 |
Brugia malayi | protein-tyrosine kinase | 0.0226 | 0.1132 | 0.1636 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0065 | 0.0183 | 0.0183 |
Loa Loa (eye worm) | DOMON domain-containing protein | 0.0046 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.038 | 0.2047 | 0.2047 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0092 | 0.0337 | 0.0443 |
Brugia malayi | SRC-1 | 0.0249 | 0.1273 | 0.184 |
Brugia malayi | Protein kinase domain containing protein | 0.0316 | 0.1665 | 0.2407 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0065 | 0.0183 | 0.0183 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0062 | 0.0164 | 0.0192 |
Loa Loa (eye worm) | trypsin family protein | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0048 | 0.008 | 0.008 |
Entamoeba histolytica | protein kinase, putative | 0.0201 | 0.0987 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0065 | 0.0183 | 0.0183 |
Onchocerca volvulus | Cathepsin L homolog | 0.0121 | 0.0512 | 0.0723 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.0275 | 0.0366 |
Schistosoma mansoni | nck2/grb4 | 0.0048 | 0.008 | 0.008 |
Echinococcus granulosus | cathepsin L | 0.0062 | 0.0164 | 0.0164 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0121 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.1722 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.038 | 0.2047 | 0.6235 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Brugia malayi | SEA domain containing protein | 0.0046 | 0.0066 | 0.0095 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0037 | 0.0013 | 0.0013 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0526 | 0.2912 | 0.2912 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0081 | 0.0275 | 0.0275 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0121 | 0.0512 | 0.0512 |
Echinococcus granulosus | Mastin | 0.0082 | 0.0278 | 0.0278 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0121 | 0.0512 | 0.0697 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Brugia malayi | cathepsin L-like precursor | 0.0081 | 0.0275 | 0.0397 |
Onchocerca volvulus | 0.0065 | 0.0183 | 0.0247 | |
Schistosoma mansoni | tyrosine kinase | 0.0514 | 0.2839 | 0.2839 |
Onchocerca volvulus | 0.0081 | 0.0275 | 0.038 | |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0065 | 0.0183 | 0.0183 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0037 | 0.0013 | 0.0013 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0065 | 0.0183 | 0.0265 |
Brugia malayi | Kringle domain containing protein | 0.0139 | 0.062 | 0.0896 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0092 | 0.0337 | 0.0337 |
Onchocerca volvulus | 0.0121 | 0.0512 | 0.0723 | |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0048 | 0.008 | 0.008 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0082 | 0.0278 | 0.0278 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0121 | 0.0512 | 0.5121 |
Onchocerca volvulus | 0.0046 | 0.0066 | 0.0077 | |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0092 | 0.0337 | 0.0256 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Schistosoma mansoni | coup transcription factor | 0.0065 | 0.0183 | 0.0183 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0226 | 0.1132 | 0.1132 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0092 | 0.0337 | 0.0337 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0065 | 0.0183 | 0.0183 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0062 | 0.0164 | 0.0237 |
Mycobacterium ulcerans | thymidylate synthase | 0.1202 | 0.6918 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.1556 |
Brugia malayi | Trypsin family protein | 0.0082 | 0.0278 | 0.0402 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0121 | 0.0512 | 0.0512 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0092 | 0.0337 | 0.0256 |
Brugia malayi | Protein kinase domain containing protein | 0.0152 | 0.0693 | 0.1002 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0253 | 0.1293 | 0.1293 |
Onchocerca volvulus | 0.0092 | 0.0337 | 0.047 | |
Entamoeba histolytica | cysteine proteinase 2 | 0.0062 | 0.0164 | 0.1556 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0121 | 0.0512 | 0.0512 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0065 | 0.0183 | 0.0265 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0973 | 0.5561 | 0.5561 |
Echinococcus granulosus | FTZ F1 alpha | 0.0065 | 0.0183 | 0.0183 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Brugia malayi | Peptidase family M1 containing protein | 0.0092 | 0.0337 | 0.0487 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Brugia malayi | thymidylate synthase | 0.1202 | 0.6918 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0065 | 0.0183 | 0.0265 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0065 | 0.0183 | 0.0183 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0121 | 0.0512 | 0.0515 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0092 | 0.0337 | 0.0573 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0037 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | insulin receptor | 0.0316 | 0.1665 | 0.1665 |
Schistosoma mansoni | tyrosine kinase | 0.0526 | 0.2912 | 0.2912 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0065 | 0.0183 | 0.0183 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0121 | 0.0512 | 0.1151 |
Leishmania major | cathepsin L-like protease | 0.0121 | 0.0512 | 0.0265 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Brugia malayi | hypothetical protein | 0.0792 | 0.4487 | 0.6486 |
Echinococcus multilocularis | NCK adaptor protein | 0.0048 | 0.008 | 0.008 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | cathepsin L | 0.0062 | 0.0164 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0512 | 0.0512 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0249 | 0.1273 | 0.1273 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0173 | 0.0821 | 0.0821 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0092 | 0.0337 | 0.0443 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0121 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0032 | 0.0032 |
Brugia malayi | nuclear receptor NHR-88 | 0.0065 | 0.0183 | 0.0265 |
Entamoeba histolytica | aminopeptidase, putative | 0.0092 | 0.0337 | 0.333 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0065 | 0.0183 | 0.0265 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0062 | 0.0164 | 0.0164 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0065 | 0.0183 | 0.0183 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0092 | 0.0337 | 0.0443 |
Schistosoma mansoni | thyroid hormone receptor | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0085 | 0.0301 | 0.0301 |
Trichomonas vaginalis | CMGC family protein kinase | 0.038 | 0.2047 | 0.6235 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0973 | 0.5561 | 0.5561 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0065 | 0.0183 | 0.0265 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0081 | 0.0275 | 0.0397 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0316 | 0.1665 | 0.1665 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0121 | 0.0512 | 0.5121 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0061 | 0.0153 | 0.0153 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.1202 | 0.6918 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0065 | 0.0183 | 0.0183 |
Echinococcus multilocularis | thymidylate synthase | 0.1202 | 0.6918 | 0.6918 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0082 | 0.0278 | 0.0278 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0048 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.1202 | 0.6918 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.1722 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0065 | 0.0183 | 0.0183 |
Schistosoma mansoni | tyrosine kinase | 0.0526 | 0.2912 | 0.2912 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0249 | 0.1273 | 0.1273 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0048 | 0.008 | 0.008 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Onchocerca volvulus | 0.1202 | 0.6918 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0065 | 0.0183 | 0.0183 |
Brugia malayi | Protein kinase domain containing protein | 0.0037 | 0.0013 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.0139 | 0.062 | 0.088 | |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0065 | 0.0183 | 0.0265 |
Trypanosoma brucei | protein kinase, putative | 0.038 | 0.2047 | 0.2788 |
Brugia malayi | Muscle positioning protein 4 | 0.0051 | 0.0095 | 0.0138 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.038 | 0.2047 | 0.2047 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0062 | 0.0164 | 0.0192 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0081 | 0.0275 | 0.0366 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0092 | 0.0337 | 0.0573 |
Brugia malayi | Variant SH3 domain containing protein | 0.0048 | 0.008 | 0.0116 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0249 | 0.1273 | 0.1273 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0061 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.038 | 0.2047 | 0.2926 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0037 | 0.0013 | 0.0013 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0121 | 0.0512 | 0.0697 |
Brugia malayi | Cathepsin L-like precursor | 0.0121 | 0.0512 | 0.074 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0092 | 0.0337 | 0.0443 |
Loa Loa (eye worm) | ctsf protein | 0.0121 | 0.0512 | 0.0512 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.1202 | 0.6918 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0065 | 0.0183 | 0.0183 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0164 | 0.1556 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0065 | 0.0183 | 0.0265 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0013 | 0.0018 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0082 | 0.0278 | 0.0278 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0121 | 0.0512 | 0.0515 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Brugia malayi | Trypsin-like protease protein 5 | 0.0082 | 0.0278 | 0.0402 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0526 | 0.2912 | 0.2912 |
Toxoplasma gondii | kringle domain-containing protein | 0.0139 | 0.062 | 0.043 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0092 | 0.0337 | 0.0337 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.038 | 0.2047 | 0.2926 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0249 | 0.1273 | 0.1273 |
Echinococcus multilocularis | tyrosine kinase | 0.0037 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0316 | 0.1665 | 0.1665 |
Plasmodium vivax | vivapain-2 | 0.0121 | 0.0512 | 0.0697 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0278 | 0.0278 |
Echinococcus granulosus | insulin receptor | 0.0316 | 0.1665 | 0.1665 |
Onchocerca volvulus | 0.0082 | 0.0278 | 0.0385 | |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0082 | 0.0278 | 0.0402 |
Onchocerca volvulus | 0.0092 | 0.0337 | 0.047 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0037 | 0.0013 | 0.0013 |
Trichomonas vaginalis | CMGC family protein kinase | 0.038 | 0.2047 | 0.6235 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0081 | 0.0275 | 0.269 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 ratio (binding) | Transcriptional activation of retinoic acid RAR-alpha receptor; Not active | ChEMBL. | No reference | |
EC50 ratio (binding) | = 17 | Transcriptional activation of retinoic acid RAR-gamma receptor | ChEMBL. | No reference |
EC50 ratio (binding) | = 100 | Transcriptional activation of retinoic acid RAR-beta receptor | ChEMBL. | No reference |
EC50 ratio (binding) | 0 | Transcriptional activation of retinoic acid RAR-alpha receptor; Not active | ChEMBL. | No reference |
EC50 ratio (binding) | = 17 | Transcriptional activation of retinoic acid RAR-gamma receptor | ChEMBL. | No reference |
EC50 ratio (binding) | = 100 | Transcriptional activation of retinoic acid RAR-beta receptor | ChEMBL. | No reference |
ED30 (functional) | mM | Concentration of the compound that induces 30% utriculi reduction in rhino mouse.; Not determined | ChEMBL. | No reference |
ED30 (functional) | 0 mM | Concentration of the compound that induces 30% utriculi reduction in rhino mouse.; Not determined | ChEMBL. | No reference |
Max (functional) | = 0 % | Maximal transcriptional activation of RAR-alpha relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 0 % | Maximal transcriptional activation of RAR-alpha relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 47 % | Maximal trascriptional activation of RAR-beta relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 47 % | Maximal trascriptional activation of RAR-beta relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 51 % | Maximal trascriptional activation of RAR-gamma relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Max (functional) | = 51 % | Maximal trascriptional activation of RAR-gamma relative to retinoic acid at 10e-6 M | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.