Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Flap structure-specific endonuclease | 0.0026 | 0.008 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.006 | 0.05 | 0.0582 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.006 | 0.05 | 0.052 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0724 | 0.8596 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0199 | 0.0199 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0032 | 0.0156 | 0.0181 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0156 | 0.0181 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0028 | 0.0114 | 0.0114 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0808 | 0.9614 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0199 | 0.0231 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.006 | 0.05 | 0.0582 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0526 | 0.0611 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0315 | 0.0315 |
Leishmania major | DNA polymerase eta, putative | 0.0031 | 0.0145 | 0.0169 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.006 | 0.05 | 0.052 |
Entamoeba histolytica | Flap nuclease, putative | 0.0026 | 0.008 | 0.0094 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0156 | 0.0181 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0026 | 0.008 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0156 | 0.0181 |
Brugia malayi | nuclear receptor RXR | 0.0028 | 0.0114 | 0.0133 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0724 | 0.8596 | 0.8596 |
Echinococcus multilocularis | geminin | 0.0166 | 0.1791 | 0.1863 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.006 | 0.05 | 0.0582 |
Echinococcus granulosus | FTZ F1 alpha | 0.006 | 0.05 | 0.05 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0526 | 0.0611 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0526 | 0.0526 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0419 | 0.4879 | 0.4879 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0315 | 0.0328 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.008 | 0.0094 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.008 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0028 | 0.0114 | 0.0119 |
Schistosoma mansoni | thyroid hormone receptor | 0.006 | 0.05 | 0.05 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.008 | 0.0094 |
Plasmodium falciparum | flap endonuclease 1 | 0.0026 | 0.008 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.007 | 0.0082 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.006 | 0.05 | 0.052 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0028 | 0.0114 | 0.0114 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0028 | 0.0114 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Schistosoma mansoni | nuclear receptor | 0.0028 | 0.0114 | 0.0114 |
Brugia malayi | nuclear hormone receptor | 0.006 | 0.05 | 0.0582 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.007 | 0.0082 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0031 | 0.0145 | 0.0169 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0315 | 0.0315 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.007 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0156 | 0.0181 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0526 | 0.0611 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0526 | 0.0526 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.006 | 0.05 | 0.0582 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0028 | 0.0114 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0315 | 0.0367 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.006 | 0.05 | 0.0582 |
Onchocerca volvulus | 0.006 | 0.05 | 1 | |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0724 | 0.8596 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0044 | 0.0304 | 0.0354 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.006 | 0.05 | 0.0582 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0304 | 0.0354 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0026 | 0.008 | 0.0084 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0526 | 0.0611 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0028 | 0.0114 | 0.0119 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0028 | 0.0114 | 0.0133 |
Echinococcus multilocularis | FTZ F1 alpha | 0.006 | 0.05 | 0.052 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.006 | 0.05 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0032 | 0.0156 | 0.0181 |
Loa Loa (eye worm) | DR-78 | 0.0028 | 0.0114 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.007 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.05 | 0.0582 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1791 | 0.1791 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0724 | 0.8596 | 1 |
Schistosoma mansoni | flap endonuclease-1 | 0.0023 | 0.0051 | 0.0051 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.006 | 0.05 | 0.05 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.006 | 0.05 | 0.052 |
Brugia malayi | nuclear receptor NHR-88 | 0.0028 | 0.0114 | 0.0133 |
Brugia malayi | nuclear receptor RXR | 0.0032 | 0.0156 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.006 | 0.05 | 0.05 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.05 | 0.0582 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0044 | 0.0304 | 0.0354 |
Onchocerca volvulus | Bile acid receptor homolog | 0.006 | 0.05 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0044 | 0.0304 | 0.0354 |
Schistosoma mansoni | thyroid hormone receptor | 0.006 | 0.05 | 0.05 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0199 | 0.0231 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.006 | 0.05 | 0.052 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.006 | 0.05 | 0.0582 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0419 | 0.4879 | 0.5074 |
Schistosoma mansoni | zinc finger protein | 0.0028 | 0.0114 | 0.0114 |
Schistosoma mansoni | DNA polymerase eta | 0.0044 | 0.0304 | 0.0304 |
Echinococcus granulosus | flap endonuclease 1 | 0.0026 | 0.008 | 0.008 |
Schistosoma mansoni | nuclear hormone receptor | 0.0028 | 0.0114 | 0.0114 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0724 | 0.8596 | 1 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0026 | 0.008 | 0.0094 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.006 | 0.05 | 0.0582 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.006 | 0.05 | 0.05 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0028 | 0.0114 | 0.0133 |
Schistosoma mansoni | nuclear hormone receptor | 0.0028 | 0.0114 | 0.0114 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.006 | 0.05 | 0.052 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.006 | 0.05 | 0.05 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.006 | 0.05 | 0.0582 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0028 | 0.0114 | 0.0133 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0032 | 0.0156 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0028 | 0.0114 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Brugia malayi | steroid hormone receptor | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.007 | 0.0082 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0031 | 0.0145 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0724 | 0.8596 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.006 | 0.05 | 0.05 |
Brugia malayi | Flap endonuclease-1 | 0.0026 | 0.008 | 0.0094 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0028 | 0.0114 | 0.0114 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.006 | 0.05 | 0.05 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.006 | 0.05 | 0.05 |
Brugia malayi | nuclear hormone receptor | 0.0028 | 0.0114 | 0.0133 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0199 | 0.0231 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0156 | 0.0181 |
Echinococcus multilocularis | dna polymerase eta | 0.0044 | 0.0304 | 0.0316 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.006 | 0.05 | 0.05 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0032 | 0.0156 | 0.0156 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.006 | 0.05 | 0.05 |
Leishmania major | DNA polymerase eta, putative | 0.0044 | 0.0304 | 0.0354 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0199 | 0.0207 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1791 | 0.1791 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0028 | 0.0114 | 0.0133 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.006 | 0.05 | 0.05 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0028 | 0.0114 | 0.0114 |
Brugia malayi | ecdysone receptor | 0.0028 | 0.0114 | 0.0133 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Brugia malayi | ecdysteroid receptor | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0156 | 0.0181 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.006 | 0.05 | 0.0582 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.006 | 0.05 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0028 | 0.0114 | 0.0114 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0315 | 0.0315 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0526 | 0.0526 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0315 | 0.0315 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.006 | 0.05 | 0.0582 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0526 | 0.0526 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0724 | 0.8596 | 0.8596 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0156 | 0.0181 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.006 | 0.05 | 0.05 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.05 | 0.0582 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0526 | 0.0547 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0526 | 0.0611 |
Loa Loa (eye worm) | steroid hormone receptor | 0.006 | 0.05 | 0.0582 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0199 | 0.0199 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0028 | 0.0114 | 0.0133 |
Brugia malayi | hypothetical protein | 0.0025 | 0.007 | 0.0082 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.006 | 0.05 | 0.05 |
Brugia malayi | tailless protein | 0.0028 | 0.0114 | 0.0133 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.006 | 0.05 | 0.0582 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0199 | 0.0231 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0526 | 0.0526 |
Schistosoma mansoni | coup transcription factor | 0.006 | 0.05 | 0.05 |
Brugia malayi | nuclear receptor NHR-67 | 0.0028 | 0.0114 | 0.0133 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.006 | 0.05 | 0.0582 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0724 | 0.8596 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0028 | 0.0114 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Brugia malayi | conserved hypotetical protein | 0.0028 | 0.0114 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0724 | 0.8596 | 0.8941 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0028 | 0.0114 | 0.0133 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.05 | 0.0582 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0028 | 0.0114 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.05 | 0.0582 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0026 | 0.008 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.006 | 0.05 | 0.05 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.006 | 0.05 | 0.05 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0028 | 0.0114 | 0.0119 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.006 | 0.05 | 0.052 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.05 | 0.0582 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0028 | 0.0114 | 0.0114 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0032 | 0.0156 | 0.0181 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0315 | 0.0328 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0724 | 0.8596 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0028 | 0.0114 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.006 | 0.05 | 0.05 |
Brugia malayi | nuclear receptor NHR-88 | 0.006 | 0.05 | 0.0582 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.006 | 0.05 | 0.052 |
Schistosoma mansoni | nuclear receptor | 0.0028 | 0.0114 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0315 | 0.0367 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0028 | 0.0114 | 0.0133 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0526 | 0.0611 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0114 | 0.0133 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.006 | 0.05 | 0.0582 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.006 | 0.05 | 0.0582 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0315 | 0.0315 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0526 | 0.0526 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0199 | 0.0199 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0199 | 0.0231 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.006 | 0.05 | 0.05 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.006 | 0.05 | 0.0582 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.006 | 0.05 | 0.0582 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0032 | 0.0156 | 0.0156 |
Echinococcus granulosus | geminin | 0.0166 | 0.1791 | 0.1791 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0026 | 0.008 | 0.1335 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0032 | 0.0156 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.05 | 0.0582 |
Echinococcus granulosus | dna polymerase eta | 0.0044 | 0.0304 | 0.0304 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0028 | 0.0114 | 0.0133 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.