Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0201 | 0.5576 | 0.5 |
Echinococcus granulosus | twitchin | 0.0029 | 0.0484 | 0.0868 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0475 | 0.0475 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0201 | 0.5576 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0638 | 0.0638 |
Schistosoma mansoni | nephrin | 0.0027 | 0.043 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0022 | 0.0267 | 0.0479 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0201 | 0.5576 | 0.5 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0022 | 0.0267 | 0.0479 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Echinococcus multilocularis | roundabout 2 | 0.0034 | 0.0638 | 0.1145 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0201 | 0.5576 | 0.5 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0328 | 0.9317 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Echinococcus granulosus | roundabout 2 | 0.0034 | 0.0638 | 0.1145 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0201 | 0.5576 | 0.5 |
Schistosoma mansoni | cell adhesion molecule | 0.0029 | 0.0475 | 0.0852 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0201 | 0.5576 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0201 | 0.5576 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Echinococcus multilocularis | Immunoglobulin | 0.0022 | 0.0267 | 0.0479 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0201 | 0.5576 | 0.5 |
Echinococcus granulosus | Immunoglobulin | 0.0022 | 0.0267 | 0.0479 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0022 | 0.0267 | 0.0267 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0201 | 0.5576 | 1 |
Echinococcus granulosus | defective proboscis extension response | 0.0022 | 0.0267 | 0.0479 |
Echinococcus multilocularis | neuroglian | 0.0027 | 0.043 | 0.0771 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0201 | 0.5576 | 0.5576 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0029 | 0.0475 | 0.0852 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0201 | 0.5576 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0201 | 0.5576 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0638 | 0.0638 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0201 | 0.5576 | 0.5 |
Echinococcus granulosus | neuroglian | 0.0027 | 0.043 | 0.0771 |
Brugia malayi | MAP kinase sur-1 | 0.0201 | 0.5576 | 0.5576 |
Onchocerca volvulus | 0.0321 | 0.9096 | 0.9763 | |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0014 | 0.0054 | 0.0054 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0201 | 0.5576 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0201 | 0.5576 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0201 | 0.5576 | 0.5 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0022 | 0.0267 | 0.0479 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0201 | 0.5576 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0201 | 0.5576 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0015 | 0.0058 | 0.0104 |
Trypanosoma brucei | protein kinase, putative | 0.0201 | 0.5576 | 0.5 |
Echinococcus multilocularis | Immunoglobulin | 0.0022 | 0.0267 | 0.0479 |
Schistosoma mansoni | vesicular amine transporter | 0.0022 | 0.0267 | 0.0479 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0201 | 0.5576 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.