Detailed information for compound 1623276

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 295.332 | Formula: C18H17NO3
  • H donors: 1 H acceptors: 3 LogP: 2.54 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)[C@H]1CCC(=O)N1Cc1ccc(cc1)c1ccccc1
  • InChi: 1S/C18H17NO3/c20-17-11-10-16(18(21)22)19(17)12-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9,16H,10-12H2,(H,21,22)/t16-/m1/s1
  • InChiKey: VMVUOYMLEJABRL-MRXNPFEDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0067 0.0339
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0026 0.013 0.013
Onchocerca volvulus 0.0015 0.006 0.0208
Trichomonas vaginalis adenosine diphosphatase, putative 0.0067 0.0381 0.1912
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0611 0.3787 1
Brugia malayi chromobox protein homolog 3 0.004 0.0212 0.022
Schistosoma mansoni chromatin regulatory protein sir2 0.0083 0.0483 0.0483
Plasmodium vivax multidomain scavenger receptor, putative 0.0027 0.0132 0.0175
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0077 0.0189
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0067 0.0067
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.006 0.006
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0217 0.1324 0.2143
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Echinococcus multilocularis ubiquitin specific protease 41 0.0029 0.0144 0.0144
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0067 0.0109
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0611 0.3787 0.613
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0033 0.017 0.017
Echinococcus granulosus axis inhibition protein axin 0.0014 0.005 0.005
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0077 0.0462
Leishmania major mitochondrial DNA polymerase beta 0.0195 0.1183 0.1183
Echinococcus granulosus pyruvate kinase 0.0022 0.0099 0.0099
Loa Loa (eye worm) sirtuin 4 0.0025 0.0122 0.0126
Brugia malayi GnHR receptor homolog 0.0015 0.006 0.0063
Plasmodium falciparum nucleoside-diphosphatase, putative 0.0067 0.0381 0.0519
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0119 0.0119
Brugia malayi neuropeptide F receptor 0.0015 0.006 0.0063
Schistosoma mansoni chromobox protein 0.0062 0.035 0.035
Mycobacterium ulcerans NAD-dependent deacetylase 0.0036 0.0192 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0236 0.0236
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0068 0.0068
Echinococcus multilocularis chromatin regulatory protein sir2 0.0083 0.0483 0.0483
Leishmania major trypanothione reductase 0.0048 0.0263 0.0263
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0027 0.0135 0.0219
Onchocerca volvulus 0.0015 0.006 0.0208
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.002 0.0087 0.0113
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Brugia malayi ImpB/MucB/SamB family protein 0.007 0.0401 0.0416
Echinococcus granulosus g protein coupled receptor 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Schistosoma mansoni cpg binding protein 0.0029 0.0147 0.0147
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0077 0.0125
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0645 0.1692
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0067 0.0381 0.1912
Trichomonas vaginalis chromobox protein, putative 0.0062 0.035 0.1757
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.006 0.006
Echinococcus granulosus p2X purinoceptor 4 0.046 0.2841 0.2841
Mycobacterium ulcerans galactokinase 0.0015 0.006 0.0143
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0078 0.0454 0.1186
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0008 0.0012 0.0012
Leishmania major dihydrolipoamide acetyltransferase precursor, putative 0.0056 0.0315 0.0315
Trichomonas vaginalis rotamase, putative 0.0024 0.0114 0.0575
Echinococcus multilocularis regulator of G protein signaling 3 0.0014 0.005 0.005
Trypanosoma brucei ingi protein (ORF1) 0.0008 0.0012 0.0012
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Echinococcus multilocularis musashi 0.0017 0.0073 0.0073
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0067 0.0381 0.0381
Mycobacterium ulcerans Sir2-like regulatory protein 0.0025 0.0122 0.0307
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0053 0.0298 0.0298
Echinococcus granulosus nuclear factor of activated T cells 5 0.0047 0.0261 0.0261
Schistosoma mansoni phosphoglucomutase 0.0007 0.0008 0.0008
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0043 0.007
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0195 0.1183 0.1916
Echinococcus multilocularis glycerol 3 phosphate dehydrogenase (NAD+) 0.0007 0.0006 0.0006
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0077 0.0781
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Echinococcus granulosus pyruvate kinase 0.0011 0.0033 0.0033
Schistosoma mansoni P2X receptor subunit 0.0247 0.1513 0.1513
Mycobacterium tuberculosis Biotinylated protein TB7.3 0.0056 0.0315 0.0819
Schistosoma mansoni chromatin regulatory protein sir2 0.0083 0.0483 0.0483
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0021 0.0096 0.0574
Echinococcus multilocularis Protein lozenge 0.0054 0.0299 0.0299
Leishmania major ATP diphosphohydrolase 0.0098 0.0579 0.0579
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0122 0.0731 0.0731
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.0154 0.0928 0.2438
Echinococcus granulosus galactokinase 0.0015 0.006 0.006
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0045 0.0245 0.0397
Brugia malayi Regulator of G protein signaling domain containing protein 0.0014 0.005 0.0052
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0029 0.0144 0.0144
Trichomonas vaginalis chromobox protein, putative 0.002 0.0087 0.0439
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.002 0.0087 0.0521
Onchocerca volvulus 0.0015 0.006 0.0208
Entamoeba histolytica hypothetical protein 0.002 0.0087 0.0521
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.006 0.0063
Plasmodium vivax hypothetical protein, conserved 0.002 0.0087 0.0113
Plasmodium vivax dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative 0.0056 0.0315 0.0429
Toxoplasma gondii histone deacetylase SIR2-like 0.0025 0.0122 0.0122
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0225 0.1131
Echinococcus granulosus expressed protein 0.0024 0.0114 0.0114
Plasmodium falciparum flap endonuclease 1 0.0019 0.0081 0.0105
Trypanosoma brucei pyruvate kinase 1, putative 0.0022 0.0099 0.0099
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0036 0.0192 0.0963
Echinococcus granulosus protein arginine N methyltransferase 8 0.0019 0.0086 0.0086
Wolbachia endosymbiont of Brugia malayi branched-chain alpha-keto acid dehydrogenase subunit E2 0.0056 0.0315 0.0819
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0007 0.001 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0011 0.0015
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0009 0.0022 0.0023
Echinococcus granulosus regulator of G protein signaling 3 0.0014 0.005 0.005
Echinococcus granulosus sex peptide receptor 0.0015 0.006 0.006
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.002 0.0087 0.0087
Echinococcus multilocularis fmrfamide receptor 0.0015 0.006 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0253
Schistosoma mansoni pyruvate carboxylase 0.0611 0.3787 0.3787
Schistosoma mansoni DNA helicase recq5 0.0025 0.0119 0.0119
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.006 0.006
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0067 0.0085
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0051 0.0282 0.073
Brugia malayi NAD-dependent deacetylase SIRT1 0.0091 0.0535 0.0555
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.006 0.006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0164 0.0989 0.1025
Plasmodium vivax pyruvate kinase 2, putative 0.0011 0.0033 0.0038
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.006 0.006
Echinococcus multilocularis Biotin lipoyl attachment 0.0056 0.0315 0.0315
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.006 0.006
Loa Loa (eye worm) runx1 0.0054 0.0299 0.031
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0346 0.0346
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.006 0.006
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0056 0.0315 0.0327
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0041 0.0223 0.0223
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0007 0.0011 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.006 0.006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0127 0.0636
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0067 0.0381 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0087 0.0439
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0611 0.3787 0.613
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0012 0.0038 0.0084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0127 0.0636
Trypanosoma brucei unspecified product 0.0008 0.0012 0.0012
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0217 0.1324 0.1324
Plasmodium falciparum lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 0.0056 0.0315 0.0429
Mycobacterium leprae conserved hypothetical protein 0.0013 0.0045 0.0105
Echinococcus multilocularis microtubule associated protein 2 0.042 0.2591 0.2591
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0087 0.0439
Schistosoma mansoni chromatin regulatory protein sir2 0.0025 0.0122 0.0122
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0025 0.0119 0.0123
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.0154 0.0928 0.2438
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0253
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0009 0.0022 0.0023
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0146 0.0877 0.4404
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0273 0.1675 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0127 0.0636
Schistosoma mansoni hypothetical protein 0.0014 0.0051 0.0051
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.006 0.006
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0067 0.0163
Schistosoma mansoni biogenic amine receptor 0.0015 0.006 0.006
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0008 0.0011 0.0015
Trypanosoma brucei chrX additional, unordered contigs 0.0017 0.0068 0.0068
Echinococcus granulosus N acetylgalactosamine kinase 0.0007 0.0008 0.0008
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0087 0.0113
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0008 0.0016 0.0016
Brugia malayi hypoxia-induced factor 1 0.0044 0.0237 0.0245
Onchocerca volvulus 0.0015 0.006 0.0208
Loa Loa (eye worm) hypothetical protein 0.0017 0.0073 0.0075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.006 0.006
Echinococcus multilocularis serotonin receptor 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Leishmania major dihydrolipoamide acetyltransferase precursorlike protein 0.0056 0.0315 0.0315
Echinococcus granulosus lamin 0.0017 0.0073 0.0073
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.006 0.0063
Treponema pallidum ATP-dependent DNA helicase 0.0013 0.0043 0.0406
Echinococcus multilocularis chromobox protein 1 0.0062 0.035 0.035
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0217 0.1324 0.2143
Onchocerca volvulus 0.0015 0.006 0.0208
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0019 0.0081 0.0132
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.006 0.006
Trypanosoma cruzi pyruvate kinase 2, putative 0.0022 0.0099 0.016
Brugia malayi fructose-bisphosphate aldolase 2 0.0055 0.031 0.0321
Toxoplasma gondii peptidylprolyl isomerase 0.0023 0.0111 0.0111
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0077 0.0462
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0055 0.031 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0087 0.0439
Onchocerca volvulus 0.0015 0.006 0.0208
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0019 0.0081 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.011
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0217 0.1324 0.3486
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0067 0.0067
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0007 0.0008 0.0006
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0217 0.1324 0.3486
Echinococcus granulosus dna polymerase kappa 0.008 0.0466 0.0466
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0019 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0003 0.0016
Trypanosoma brucei unspecified product 0.0037 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0052
Schistosoma mansoni lamin 0.0017 0.0073 0.0073
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0049 0.0273 0.0283
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0096 0.0483
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.1603 1 1
Brugia malayi Nucleoside-diphosphatase mig-23 0.0067 0.0381 0.0395
Mycobacterium leprae Probable biotinylated protein homolog TB7.3 0.0056 0.0315 0.0819
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0135 0.0219
Trypanosoma cruzi peter pan protein, putative 0.0163 0.0984 0.1593
Brugia malayi Pre-SET motif family protein 0.0041 0.0223 0.0231
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0056 0.0315 0.0327
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0067 0.0163
Brugia malayi Serotonin receptor 0.0015 0.006 0.0063
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0096 0.0125
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) CHromoDomain protein family member 0.0021 0.0097 0.0101
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0007 0.0011 0.0013
Trypanosoma cruzi ribonuclease H1, putative 0.0007 0.0008 0.0013
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0025 0.0122 0.0122
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.006 0.0208
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0611 0.3787 0.3787
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0263 0.068
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.006 0.006
Schistosoma mansoni pyruvate kinase 0.0022 0.0099 0.0099
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0055 0.031 0.031
Schistosoma mansoni hypothetical protein 0.0026 0.0129 0.0129
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0024 0.0114 0.0119
Giardia lamblia Ribonuclease H 0.0007 0.0008 0.0048
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0021 0.0097 0.0097
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0021 0.0096 0.0483
Brugia malayi Dopamine receptor 0.0015 0.006 0.0063
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Echinococcus multilocularis lipoxygenase domain containing protein 0.0027 0.0132 0.0132
Echinococcus granulosus Chromobox protein 3 0.002 0.0087 0.0087
Brugia malayi RNase H family protein 0.0007 0.0008 0.0008
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0083 0.0483 0.0782
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0014 0.005 0.005
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0096 0.0483
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0053 0.0298 0.0298
Echinococcus granulosus chromobox protein 2 0.002 0.0087 0.0087
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0055 0.031 0.0501
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0611 0.3787 1
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.006 0.006
Wolbachia endosymbiont of Brugia malayi DNA polymerase III alpha subunit 0.0153 0.0923 0.2425
Trypanosoma cruzi nucleoside phosphatase, putative 0.0067 0.0381 0.0616
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0016 0.0016
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0083 0.0482 0.0482
Loa Loa (eye worm) hypothetical protein 0.0022 0.0102 0.0106
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0104 0.0615 0.3086
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.006 0.006
Schistosoma mansoni 6-phosphofructokinase 0.0078 0.0454 0.0454
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0645 0.1692
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.006 0.0063
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.0154 0.0928 0.2438
Loa Loa (eye worm) hypothetical protein 0.0022 0.0099 0.0102
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0056 0.0315 0.0511
Trypanosoma brucei DNA polymerase IV, putative 0.008 0.0466 0.0466
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.006 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0466 0.0466
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.009 0.0528 0.0528
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0077 0.0099
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.006 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0007 0.0011 0.0011
Schistosoma mansoni phosphoglucomutase 0.0007 0.0008 0.0008
Schistosoma mansoni lipoxygenase 0.0161 0.0972 0.0972
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0003 0.0016
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0029 0.0144 0.0144
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0008 0.0011 0.0015
Brugia malayi hypothetical protein 0.0011 0.0036 0.0037
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.002 0.0087 0.0087
Echinococcus granulosus microtubule associated protein 2 0.042 0.2591 0.2591
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0466 0.0466
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0091 0.0532 0.0532
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0031 0.0159 0.0212
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0091 0.0535 0.0535
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0067 0.0067
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0611 0.3787 1
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0025 0.0119 0.0157
Schistosoma mansoni ap endonuclease 0.0018 0.0077 0.0077
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.002 0.0087 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.006 0.006
Schistosoma mansoni flap endonuclease-1 0.0017 0.007 0.007
Brugia malayi Uncoordinated protein 44 0.0009 0.0022 0.0023
Trichomonas vaginalis inositol monophosphatase, putative 0.0012 0.0038 0.0189
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0217 0.1324 0.1324
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.006 0.006
Plasmodium falciparum thioredoxin reductase 0.0017 0.0067 0.0085
Giardia lamblia Phosphoglycerate kinase 0.0122 0.0731 0.4362
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0217 0.1324 0.3486
Loa Loa (eye worm) galactokinase 0.0007 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Schistosoma mansoni guanosine-diphosphatase 0.0067 0.0381 0.0381
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0122 0.0731 0.0731
Loa Loa (eye worm) hypothetical protein 0.0008 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0015 0.0058 0.006
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0122 0.0731 0.1918
Schistosoma mansoni aryl hydrocarbon receptor 0.0014 0.0052 0.0052
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0127 0.0636
Brugia malayi Carboxyl transferase domain containing protein 0.1547 0.9648 1
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0055 0.031 0.0501
Mycobacterium ulcerans putative regulatory protein 0.001 0.0029 0.0062
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Echinococcus multilocularis transfer RNA-Lys 0.001 0.0029 0.0029
Brugia malayi Type III restriction enzyme, res subunit family protein 0.002 0.0087 0.0091
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0055 0.031 0.031
Trypanosoma brucei brix domain containing protein, putative 0.0163 0.0984 0.0984
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0056 0.0315 0.0315
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.0068 0.0068
Entamoeba histolytica acyl-coA synthetase, putative 0.0008 0.0011 0.0067
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0091
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0067 0.0067
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0091 0.0532 0.0532
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0007 0.0011 0.0053
Schistosoma mansoni peter pan-related 0.0163 0.0984 0.0984
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0049 0.0268 0.0434
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0009 0.0022 0.0023
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0043 0.007
Echinococcus multilocularis pyruvate kinase 0.0011 0.0033 0.0033
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0012 0.0038 0.0189
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0217 0.1324 0.3487
Schistosoma mansoni hypothetical protein 0.0015 0.006 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Trichomonas vaginalis helicase, putative 0.0006 0.0003 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0067 0.0109
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0212 0.0784
Leishmania major cathepsin L-like protease 0.0018 0.0079 0.0079
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.006 0.0063
Schistosoma mansoni histamine h1 receptor 0.0015 0.006 0.006
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0098 0.0579 0.0579
Echinococcus multilocularis g protein coupled receptor 0.0015 0.006 0.006
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.006 0.006
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0195 0.1183 0.1183
Entamoeba histolytica phosphofructokinase, putative 0.0078 0.0454 0.2708
Trypanosoma brucei trypanothione reductase 0.0048 0.0263 0.0263
Brugia malayi Brix domain containing protein 0.0163 0.0984 0.102
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.009 0.0528 0.0855
Loa Loa (eye worm) pyruvate kinase 0.0022 0.0099 0.0102
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0056 0.0315 0.0315
Loa Loa (eye worm) glutathione reductase 0.0048 0.0263 0.0272
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.006 0.006
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0017 0.0069 0.0112
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0056 0.0315 0.0327
Toxoplasma gondii brix domain-containing protein 0.0163 0.0984 0.0984
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Entamoeba histolytica pyruvate kinase, putative 0.0015 0.0058 0.0345
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0007 0.0011 0.0014
Plasmodium falciparum dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 0.0056 0.0315 0.0429
Brugia malayi PXA domain containing protein 0.0014 0.005 0.0052
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0011 0.0012
Trichomonas vaginalis galactokinase, putative 0.0007 0.0008 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0003 0.0016
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0025 0.0122 0.0727
Onchocerca volvulus 0.0008 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.002 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.006 0.006
Trichomonas vaginalis glycerol-3-phosphate dehydrogenase, putative 0.0007 0.0006 0.0029
Brugia malayi fructose-bisphosphate aldolase 1 0.0055 0.031 0.0321
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0056 0.0315 0.0315
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.006 0.006
Plasmodium falciparum LCCL domain-containing protein 0.0027 0.0132 0.0175
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.0138 0.0828 0.0828
Treponema pallidum galactokinase 0.0013 0.0047 0.0452
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0049 0.0273 0.0708
Onchocerca volvulus 0.0015 0.006 0.0208
Echinococcus granulosus ubiquitin specific protease 41 0.0029 0.0144 0.0144
Schistosoma mansoni chromobox protein 0.002 0.0087 0.0087
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.006 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0466 0.0466
Entamoeba histolytica hypothetical protein 0.0014 0.005 0.03
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0023 0.0111 0.0111
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0036 0.0192 0.0311
Loa Loa (eye worm) phosphofructokinase 0.0078 0.0454 0.047
Schistosoma mansoni biogenic amine receptor 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0091 0.0535 0.0555
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.004 0.0041
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0019 0.0081 0.0081
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0056 0.0315 0.0315
Schistosoma mansoni hypothetical protein 0.0027 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0427 0.2636 0.2732
Schistosoma mansoni acetyl-CoA carboxylase 0.1603 1 1
Brugia malayi cytoplasmic intermediate filament protein 0.0009 0.0022 0.0023
Echinococcus granulosus L aminoadipate semialdehyde 0.0026 0.013 0.013
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.006 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.006 0.006
Trichomonas vaginalis chromobox protein, putative 0.0062 0.035 0.1757
Echinococcus multilocularis expressed protein 0.0269 0.1646 0.1646
Loa Loa (eye worm) hypothetical protein 0.0041 0.0223 0.0231
Onchocerca volvulus 0.0028 0.0137 0.05
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0078 0.0454 0.1185
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Echinococcus granulosus bloom syndrome protein 0.0033 0.017 0.017
Entamoeba histolytica hypothetical protein 0.0025 0.012 0.0716
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0025 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0091 0.0535 0.2687
Toxoplasma gondii exonuclease III APE 0.0018 0.0077 0.0077
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0041 0.0223 0.0223
Schistosoma mansoni phosphoglycerate kinase 0.0122 0.0731 0.0731
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.013 0.065
Brugia malayi Probable glycerol-3-phosphate dehydrogenase, cytoplasmic 0.0007 0.0006 0.0006
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0036 0.0192 0.0258
Loa Loa (eye worm) hypothetical protein 0.0066 0.0377 0.0391
Loa Loa (eye worm) glycerol-3-Phosphate DeHydrogenase family member 0.0007 0.0006 0.0006
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0019 0.0086 0.0086
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0055 0.031 0.031
Leishmania major nucleoside phosphatase, putative,guanosine diphosphatase, putative 0.0098 0.0579 0.0579
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0611 0.3787 0.3787
Echinococcus multilocularis regulator of G protein signaling 7 0.0014 0.005 0.005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0087 0.0439
Brugia malayi RNase H family protein 0.0007 0.0008 0.0008
Trichomonas vaginalis hypothetical protein 0.002 0.0087 0.0439
Plasmodium falciparum heterochromatin protein 1 0.002 0.0087 0.0113
Brugia malayi Immunoglobulin I-set domain containing protein 0.0009 0.0022 0.0023
Brugia malayi Serotonin receptor 0.0015 0.006 0.0063
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0008 0.0011 0.0015
Trichomonas vaginalis adenosine diphosphatase, putative 0.0067 0.0381 0.1912
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0253
Echinococcus multilocularis serotonin receptor 0.0015 0.006 0.006
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0012 0.0038 0.0225
Onchocerca volvulus 0.0015 0.006 0.0208
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.006 0.006
Schistosoma mansoni axis inhibition protein axin 0.0014 0.005 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.008 0.0466 0.0755
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0052
Schistosoma mansoni pyruvate kinase 0.0022 0.0099 0.0099
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.006 0.006
Schistosoma mansoni glutaminase 0.0087 0.0509 0.0509
Schistosoma mansoni survival motor neuron protein 0.0014 0.0051 0.0051
Onchocerca volvulus 0.0015 0.006 0.0208
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0096 0.0483
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0096 0.0483
Echinococcus granulosus Biotin lipoyl attachment 0.0056 0.0315 0.0315
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.006 0.006
Brugia malayi glutaminase DH11.1 0.0087 0.0509 0.0528
Mycobacterium tuberculosis Conserved hypothetical protein 0.0013 0.0045 0.0105
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0014 0.005 0.0052
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0029 0.0144 0.0144
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0019 0.0086 0.043
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0027 0.0027
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0019 0.0086 0.0086
Loa Loa (eye worm) glutaminase 0.0087 0.0509 0.0528
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0026 0.013 0.0135
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0078 0.0454 0.0454
Brugia malayi hypothetical protein 0.0014 0.005 0.0052
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.0007 0.0006 0.0006
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.006 0.006
Schistosoma mansoni amine GPCR 0.0015 0.006 0.006
Brugia malayi sulfakinin receptor protein 0.0015 0.006 0.0063
Leishmania major DNA damage repair protein, putative 0.0017 0.0068 0.0068
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0055 0.031 0.0501
Schistosoma mansoni aspartate carbamoyltransferase 0.0138 0.0828 0.0828
Echinococcus multilocularis lamin 0.0017 0.0073 0.0073
Onchocerca volvulus 0.0015 0.006 0.0208
Loa Loa (eye worm) hypothetical protein 0.0021 0.0094 0.0097
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.0144 0.0233
Echinococcus granulosus neuropeptide receptor 0.0015 0.006 0.006
Echinococcus multilocularis Chromo domain 0.002 0.0087 0.0087
Plasmodium vivax hypothetical protein, conserved 0.002 0.0087 0.0113
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0019 0.0081 0.0081
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0067 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Trichomonas vaginalis glutaminase, putative 0.0087 0.0509 0.2558
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0007 0.001 0.001
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0067 0.0381 0.0381
Loa Loa (eye worm) PXA domain-containing protein 0.0014 0.005 0.0052
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0454 0.2278
Schistosoma mansoni cpg binding protein 0.0029 0.0147 0.0147
Mycobacterium leprae Probable pyruvate kinase PykA 0.0022 0.0099 0.0246
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0052
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0025 0.0122 0.0122
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.006 0.006
Onchocerca volvulus 0.0015 0.006 0.0208
Echinococcus granulosus muscleblind protein 0.0053 0.0296 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0003 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.006 0.006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0132 0.0788 0.2068
Chlamydia trachomatis acetyl-CoA carboxylase biotin carboxyl carrier protein 0.0056 0.0315 0.0903
Brugia malayi neuropeptide F receptor 0.0015 0.006 0.0063
Trypanosoma cruzi galactokinase, putative 0.0015 0.006 0.0097
Brugia malayi Bloom's syndrome protein homolog 0.0033 0.017 0.0176
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0137 0.0142
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.006 0.006
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0051 0.0282 0.073
Echinococcus multilocularis peter pan 0.0163 0.0984 0.0984
Onchocerca volvulus 0.0014 0.0051 0.0173
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0079 0.0129
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.002 0.0087 0.0521
Toxoplasma gondii hypothetical protein 0.0031 0.0161 0.0161
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.006 0.0063
Echinococcus granulosus dnaJ subfamily B 0.0249 0.1521 0.1521
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.009 0.0528 0.0855
Echinococcus multilocularis regulator of G protein signaling 3 0.0014 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0091
Brugia malayi intermediate filament protein 0.0017 0.0073 0.0075
Echinococcus granulosus serotonin receptor 0.0015 0.006 0.006
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0014 0.005 0.005
Entamoeba histolytica deoxycytidyl transferase, putative 0.0053 0.0298 0.178
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.006 0.034 0.0884
Loa Loa (eye worm) 6-phosphofructokinase 0.0078 0.0454 0.047
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.004 0.0041
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0083 0.0483 0.0782
Onchocerca volvulus Pyruvate kinase homolog 0.0022 0.0099 0.0353
Plasmodium vivax flap endonuclease 1, putative 0.0019 0.0081 0.0105
Brugia malayi Intermediate filament tail domain containing protein 0.0017 0.0073 0.0075
Onchocerca volvulus 0.0017 0.0073 0.0255
Trichomonas vaginalis chromobox protein, putative 0.002 0.0087 0.0439
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.006 0.006
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0008 0.0016 0.0016
Plasmodium vivax lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative 0.0056 0.0315 0.0429
Trypanosoma cruzi DNA damage repair protein, putative 0.0017 0.0068 0.011
Loa Loa (eye worm) hypothetical protein 0.0049 0.0273 0.0283
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0092 0.0541 0.0541
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0104 0.0615 0.3086
Echinococcus multilocularis flap endonuclease 1 0.0019 0.0081 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.006 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Brugia malayi Protein kinase domain containing protein 0.0009 0.0022 0.0023
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0067 0.0085
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0056 0.0315 0.0315
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.006 0.0063
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0014 0.005 0.0052
Loa Loa (eye worm) hypothetical protein 0.0013 0.0045 0.0047
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0122 0.0731 0.1918
Entamoeba histolytica brix domain containing protein 0.0163 0.0984 0.5875
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.006 0.006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0067 0.0109
Trypanosoma brucei DNA damage repair protein, putative 0.0017 0.0068 0.0068
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0067 0.0067
Brugia malayi Melatonin receptor type 1A 0.0015 0.006 0.0063
Trypanosoma brucei phosphoglycerate kinase, putative 0.0045 0.0245 0.0245
Schistosoma mansoni amine GPCR 0.0015 0.006 0.006
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Schistosoma mansoni microtubule-associated protein tau 0.042 0.2591 0.2591
Echinococcus multilocularis regulator of G protein signaling 7 0.0014 0.005 0.005
Brugia malayi putative neuropeptide receptor 0.0015 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0091
Brugia malayi G-protein coupled receptor 0.0015 0.006 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0466 0.0466
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.008 0.008
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0077 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.006 0.006
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0016 0.0016
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.006 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0217 0.1324 0.1324
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.009 0.0528 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0089 0.0444
Onchocerca volvulus 0.0427 0.2636 1
Schistosoma mansoni regulator of G protein signaling 0.0014 0.005 0.005
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0067 0.0085
Chlamydia trachomatis dihydrolipoamide acetyltransferase 0.0056 0.0315 0.0903
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0104 0.0615 0.3668
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.006 0.006
Echinococcus multilocularis 6 phosphofructokinase 0.0078 0.0454 0.0454
Onchocerca volvulus 0.0014 0.0053 0.0182
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0053 0.0298 0.0309
Toxoplasma gondii GHMP kinase, N-terminal domain-containing protein 0.0007 0.0008 0.0008
Leishmania major DNA polymerase eta, putative 0.007 0.0401 0.0401
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0041 0.0223 0.0223
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.1547 0.9648 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0127 0.0636
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0253
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Entamoeba histolytica phosphoglycerate kinase, putative 0.0122 0.0731 0.4362
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0454 0.2278
Schistosoma mansoni regulator of G protein signaling 0.0014 0.005 0.005
Echinococcus granulosus 3'partial|ectonucleoside triphosphate diphosphohydrolase 0.0146 0.0877 0.0877
Schistosoma mansoni amine GPCR 0.0015 0.006 0.006
Schistosoma mansoni guanosine-diphosphatase 0.0067 0.0381 0.0381
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0217 0.1324 0.3486
Trichomonas vaginalis adenosine diphosphatase, putative 0.0067 0.0381 0.1912
Echinococcus granulosus p2X purinoceptor 4 0.046 0.2841 0.2841
Echinococcus granulosus allatostatin A receptor 0.0015 0.006 0.006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0106 0.053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.006 0.006
Schistosoma mansoni DNA polymerase IV / kappa 0.0017 0.0068 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.011
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.006 0.0063
Loa Loa (eye worm) transcriptional regulator 0.0025 0.0122 0.0126
Brugia malayi Death domain containing protein 0.0009 0.0022 0.0023
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0721 0.1893
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0645 0.1692
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0104 0.0615 0.3086
Trypanosoma brucei phosphoglycerate kinase 0.0122 0.0731 0.0731
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0089 0.0444
Echinococcus granulosus tumor protein p63 0.0098 0.0576 0.0576
Trypanosoma brucei DNA polymerase eta, putative 0.007 0.0401 0.0401
Loa Loa (eye worm) flap endonuclease-1 0.0019 0.0081 0.0084
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Entamoeba histolytica hypothetical protein 0.0011 0.0036 0.0213
Echinococcus multilocularis g protein coupled receptor 0.0015 0.006 0.006
Echinococcus granulosus neuropeptide s receptor 0.0015 0.006 0.006
Schistosoma mansoni polycystin 1-related 0.0027 0.0132 0.0132
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0008 0.0011 0.0015
Mycobacterium ulcerans pyruvate carboxylase 0.0611 0.3787 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0067 0.0164
Leishmania major phosphopantetheinyl transferase-like protein 0.0007 0.0011 0.0011
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0008 0.0011 0.0015
Leishmania major arginine N-methyltransferase-like protein 0.002 0.009 0.009
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0077 0.0189
Schistosoma mansoni ap endonuclease 0.0018 0.0077 0.0077
Plasmodium vivax phosphoglycerate kinase, putative 0.0122 0.0731 0.1004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.006 0.006
Brugia malayi phosphofructokinase 0.0078 0.0454 0.047
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Schistosoma mansoni adenoreceptor 0.0015 0.006 0.006
Leishmania major peter pan protein, putative 0.0163 0.0984 0.0984
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0007 0.0011 0.0013
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0161 0.0972 0.0972
Onchocerca volvulus 0.0015 0.006 0.0208
Brugia malayi hypothetical protein 0.0068 0.0392 0.0407
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0021 0.0096 0.0096
Schistosoma mansoni regulator of G protein signaling 0.0014 0.005 0.005
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.006 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Toxoplasma gondii pyruvate kinase PyK1 0.0022 0.0099 0.0099
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0091 0.0535 0.2687
Echinococcus granulosus regulator of G protein signaling 3 0.0014 0.005 0.005
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0029 0.0144 0.086
Echinococcus multilocularis muscleblind protein 0.0053 0.0296 0.0296
Echinococcus granulosus g-protein coupled receptor 0.0015 0.006 0.006
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0055 0.031 0.031
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0056 0.0315 0.0315
Trypanosoma brucei nucleoside diphosphatase, putative 0.0098 0.0579 0.0579
Brugia malayi Dopamine receptor protein 2 0.0015 0.006 0.0063
Plasmodium falciparum thioredoxin reductase 0.0048 0.0263 0.0356
Echinococcus granulosus Ankyrin 0.0009 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0212 0.1064
Echinococcus multilocularis pyruvate kinase 0.0017 0.007 0.007
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0025 0.0122 0.0612
Echinococcus granulosus lipoxygenase domain containing protein 0.0027 0.0132 0.0132
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0083 0.0483 0.2427
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0036 0.0192 0.0963
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0096 0.0125
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0091
Onchocerca volvulus Peter pan protein homolog 0.0163 0.0984 0.372
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Schistosoma mansoni lozenge 0.0054 0.0299 0.0299
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0138 0.0828 0.0828
Echinococcus granulosus death domain containing protein 0.0009 0.0022 0.0022
Schistosoma mansoni regulator of G protein signaling 0.0014 0.005 0.005
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0007 0.001 0.0016
Toxoplasma gondii phosphofructokinase PFKII 0.0021 0.0096 0.0096
Trichomonas vaginalis ribonuclease H1, putative 0.0007 0.0008 0.004
Giardia lamblia Fructose-bisphosphate aldolase 0.0104 0.0615 0.3668
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.006 0.0063
Trypanosoma cruzi galactokinase, putative 0.0013 0.0047 0.0076
Echinococcus granulosus axis inhibition protein axin 0.0014 0.005 0.005
Brugia malayi RE15519p 0.0015 0.006 0.0063
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0078 0.0454 0.4886
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0007 0.0011 0.0007
Schistosoma mansoni pyruvate kinase 0.0011 0.0033 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0122 0.0161
Leishmania major 4-coumarate:coa ligase-like protein 0.0008 0.0011 0.0011
Echinococcus granulosus pyruvate kinase 0.0011 0.0033 0.0033
Onchocerca volvulus Pyruvate kinase homolog 0.0022 0.0099 0.0353
Onchocerca volvulus 0.0017 0.0073 0.0255
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Plasmodium vivax SET domain protein, putative 0.0041 0.0223 0.0301
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0026 0.0027
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0263 0.0272
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.006 0.006
Echinococcus granulosus g protein coupled receptor 0.0015 0.006 0.006
Brugia malayi Associated with TFs and helicases family protein 0.002 0.0087 0.0091
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.006 0.006
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0055 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.011 0.0656 0.068
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0012 0.0038 0.0189
Echinococcus multilocularis galactokinase 0.0015 0.006 0.006
Giardia lamblia DNA damage repair protein 0.0017 0.0068 0.0404
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0083 0.0483 0.0483
Echinococcus multilocularis axis inhibition protein axin 0.0014 0.005 0.005
Trichomonas vaginalis adenosine diphosphatase, putative 0.0067 0.0381 0.1912
Toxoplasma gondii NAD-dependent glycerol-3-phosphate dehydrogenase 0.0007 0.0006 0.0006
Trypanosoma brucei galactokinase-like protein, putative 0.001 0.0027 0.0027
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.006 0.0063
Echinococcus granulosus cpg binding protein 0.0029 0.0147 0.0147
Trichomonas vaginalis DNA polymerase eta, putative 0.008 0.0466 0.2341
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0017 0.0068 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0003 0.0016
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0721 0.1893
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0236 0.0236
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0077 0.0077
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0013 0.0045 0.0105
Entamoeba histolytica hypothetical protein 0.0011 0.0036 0.0213
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0014 0.005 0.0253
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.006 0.006
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0056 0.0315 0.0819
Loa Loa (eye worm) inositol-1 0.0012 0.0038 0.0039
Plasmodium falciparum glutathione reductase 0.0048 0.0263 0.0356
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0025 0.0119 0.0119
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0067 0.0109
Entamoeba histolytica Flap nuclease, putative 0.0019 0.0081 0.0485
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.006 0.006
Plasmodium vivax DNA repair protein REV1, putative 0.0017 0.0068 0.0086
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0263 0.0263
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0036 0.0192 0.1145
Echinococcus granulosus expressed protein 0.0269 0.1646 0.1646
Echinococcus granulosus histone lysine methyltransferase setb 0.0041 0.0223 0.0223
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.006 0.006
Trypanosoma cruzi DNA damage repair protein, putative 0.0017 0.0068 0.011
Trypanosoma brucei ribonuclease H1 0.0007 0.0008 0.0008
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0056 0.0315 0.0511
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0077 0.0389
Echinococcus granulosus beta-adrenergic receptor kinase 0.0014 0.005 0.005
Schistosoma mansoni cpg binding protein 0.0028 0.0137 0.0137
Treponema pallidum fructose-bisphosphate aldolase 0.0104 0.0615 0.6639
Echinococcus multilocularis pyruvate kinase 0.0022 0.0099 0.0099
Entamoeba histolytica hypothetical protein 0.0014 0.005 0.03
Schistosoma mansoni hypothetical protein 0.0011 0.0036 0.0036
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.006 0.006
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0079 0.0129
Trichomonas vaginalis Heterochromatin protein, putative 0.002 0.0087 0.0439
Plasmodium falciparum dihydrolipoamide acyltransferase component E2 0.0056 0.0315 0.0429
Brugia malayi transcriptional regulator, Sir2 family protein 0.0083 0.0483 0.0501
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0009 0.0022 0.0023
Giardia lamblia Pyruvate kinase 0.0011 0.0033 0.0197
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0055 0.031 0.031
Brugia malayi hypothetical protein 0.0025 0.012 0.0124
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0119 0.0123
Leishmania major dihydrolipoamide branched chain transacylase, putative 0.0056 0.0315 0.0315
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0122 0.0731 0.1183
Brugia malayi Thioredoxin reductase 0.0048 0.0263 0.0272
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0645 0.1692
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0056 0.0315 0.0819
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0019 0.0086 0.0111
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0068 0.0068
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0056 0.0315 0.0903
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.006 0.006
Brugia malayi transcriptional regulator, Sir2 family protein 0.0025 0.0122 0.0126
Toxoplasma gondii thioredoxin reductase 0.0048 0.0263 0.0263
Entamoeba histolytica galactokinase, putative 0.0015 0.006 0.0356
Leishmania major phosphoglycerate kinase C, glycosomal 0.0122 0.0731 0.0731
Echinococcus multilocularis p2X purinoceptor 4 0.046 0.2841 0.2841
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0083 0.0483 0.2884
Echinococcus granulosus regulator of G protein signaling 7 0.0014 0.005 0.005
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0009 0.0022 0.0022
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.1603 1 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0014 0.005 0.0052
Mycobacterium tuberculosis Probable branched-chain keto acid dehydrogenase E2 component BkdC 0.0056 0.0315 0.0819
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0225 0.1131
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0114 0.0575
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0045
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.006 0.006
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0008 0.0011 0.0015
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0067 0.0163
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.006 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0236 0.0236
Leishmania major cathepsin L-like protease 0.0018 0.0079 0.0079
Echinococcus multilocularis g protein coupled receptor 0.0015 0.006 0.006
Loa Loa (eye worm) intermediate filament protein 0.0017 0.0073 0.0075
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0119 0.0123
Brugia malayi AKH receptor 0.0015 0.006 0.0063
Onchocerca volvulus 0.0324 0.1992 0.7551
Trichomonas vaginalis pyruvate kinase, putative 0.0022 0.0099 0.0495
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0055 0.031 0.031
Brugia malayi Regulator of G protein signaling domain containing protein 0.0014 0.005 0.0052
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0122 0.0731 0.1918
Leishmania major galactokinase-like protein 0.0015 0.006 0.006
Trypanosoma cruzi pyruvate kinase 2, putative 0.0022 0.0099 0.016
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0067 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.006 0.006
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0019 0.0086 0.0086
Echinococcus granulosus pyruvate kinase 0.0011 0.0033 0.0033
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0055 0.031 0.0501
Treponema pallidum ribonuclease H (rnhA) 0.0007 0.0008 0.0025
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0611 0.3787 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0092 0.0541 0.0876
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0011 0.003 0.0064
Schistosoma mansoni hypothetical protein 0.0015 0.006 0.006
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0122 0.0731 0.367
Trypanosoma brucei SIR2-like protein 4, putative 0.0025 0.0122 0.0122
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0263 0.0263
Trichomonas vaginalis chromobox protein, putative 0.002 0.0087 0.0439
Loa Loa (eye worm) hypothetical protein 0.0056 0.0315 0.0327
Trichomonas vaginalis ssf, putative 0.0163 0.0984 0.4942
Trypanosoma cruzi cruzipain precursor, putative 0.0018 0.0079 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.006 0.006
Mycobacterium ulcerans epimerase 0.0013 0.0045 0.0105
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.013 0.021
Brugia malayi PXA domain containing protein 0.0014 0.005 0.0052
Brugia malayi Pyruvate kinase, muscle isozyme 0.0022 0.0099 0.0102
Brugia malayi hypothetical protein 0.011 0.0656 0.068
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.006 0.0063
Toxoplasma gondii dihydrolipoamide acyltransferase, putative 0.0056 0.0315 0.0315
Brugia malayi hypothetical protein 0.0427 0.2636 0.2732
Echinococcus multilocularis chromobox protein 2 0.002 0.0087 0.0087
Onchocerca volvulus 0.0015 0.006 0.0208
Echinococcus multilocularis RUN 0.0027 0.0132 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0127 0.0636
Giardia lamblia Hypothetical protein 0.0083 0.0483 0.2884
Toxoplasma gondii 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein 0.0056 0.0315 0.0315
Schistosoma mansoni netrin receptor unc5 0.0009 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0067 0.0381 0.0395
Trichomonas vaginalis pyruvate kinase, putative 0.0022 0.0099 0.0495
Mycobacterium ulcerans 6-phosphofructokinase 0.0078 0.0454 0.1185
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0083 0.0483 0.0483
Plasmodium vivax heterochromatin protein 1, putative 0.002 0.0087 0.0113
Trypanosoma brucei hypothetical protein, conserved 0.0008 0.0012 0.0012
Echinococcus granulosus flap endonuclease 1 0.0019 0.0081 0.0081
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.006 0.006
Schistosoma mansoni neuropeptide receptor 0.0015 0.006 0.006
Toxoplasma gondii histone deacetylase SIR2 0.0036 0.0192 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0466 0.0466
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0016 0.0016
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0025 0.0122 0.0122
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.006 0.0063
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.006 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0096 0.0483
Echinococcus granulosus transcription factor Dp 1 0.0052 0.029 0.029
Schistosoma mansoni amine GPCR 0.0015 0.006 0.006
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.009 0.0528 0.3151
Echinococcus multilocularis p2X purinoceptor 4 0.046 0.2841 0.2841
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.006 0.006
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0263 0.0425
Leishmania major ribonuclease H1, putative 0.0007 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Toxoplasma gondii NTPase II 0.0067 0.0381 0.0381
Echinococcus granulosus lamin dm0 0.0017 0.0073 0.0073
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0021 0.0096 0.0987
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0014 0.0051 0.0053
Plasmodium vivax NAD-dependent deacetylase, putative 0.0036 0.0192 0.0258
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0019 0.0086 0.043
Chlamydia trachomatis DNA polymerase III subunit alpha 0.0153 0.0923 0.2674
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0067 0.0109
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0454 0.2278
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0067 0.0381 0.0381
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.006 0.006
Loa Loa (eye worm) hypoxia-induced factor 1 0.0044 0.0237 0.0245
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0217 0.1324 0.3486
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0025 0.012 0.0194
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0087 0.0439
Trichomonas vaginalis DNA helicase recq1, putative 0.0033 0.017 0.0852
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0091 0.0532 0.0532
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0067 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0212 0.1064
Loa Loa (eye worm) pyruvate kinase 0.0022 0.0099 0.0102
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0078 0.0454 0.1186
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.006 0.006
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.009 0.0528 0.0547
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E2 0.0056 0.0315 0.0315
Echinococcus granulosus Regulator of G protein signaling 20 0.0014 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0108 0.0544
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0067 0.0381 0.0381
Brugia malayi polk-prov protein 0.0043 0.0236 0.0244
Mycobacterium tuberculosis Probable galactokinase GalK (galactose kinase) 0.0015 0.006 0.0143
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0036 0.0192 0.0493
Onchocerca volvulus Pyruvate kinase homolog 0.0022 0.0099 0.0353
Echinococcus multilocularis axis inhibition protein axin 0.0014 0.005 0.005
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0056 0.0315 0.0315
Trichomonas vaginalis phosphofructokinase, putative 0.0078 0.0454 0.2278
Brugia malayi hypothetical protein 0.0014 0.005 0.0052
Trypanosoma cruzi ribonuclease H1, putative 0.0007 0.0008 0.0013
Plasmodium falciparum glutathione reductase 0.0017 0.0067 0.0085
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0217 0.1324 0.3486
Schistosoma mansoni chromodomain helicase DNA binding protein 0.002 0.0087 0.0087
Schistosoma mansoni adenosine diphosphatase 0.0098 0.0579 0.0579
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Mycobacterium ulcerans DNA polymerase III subunit alpha 0.0153 0.0923 0.2425
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0025 0.012 0.0716
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0073
Leishmania major acetyl-CoA carboxylase, putative 0.1603 1 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0007 0.0011 0.0007
Mycobacterium ulcerans hypothetical protein 0.0008 0.0011 0.0015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0108 0.0544
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0056 0.0315 0.0819
Loa Loa (eye worm) hypothetical protein 0.0043 0.0236 0.0244
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0029 0.0144 0.0144
Schistosoma mansoni amine GPCR 0.0015 0.006 0.006
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0217 0.1324 0.3486
Schistosoma mansoni axis inhibition protein axin 0.0014 0.005 0.005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0067 0.0109
Onchocerca volvulus 0.0061 0.0346 0.1294
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) RecQ helicase 0.0033 0.017 0.0176
Plasmodium falciparum pyruvate kinase 2 0.0011 0.0033 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0087 0.0439
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0056 0.0315 0.0315
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0078 0.0454 0.1186
Echinococcus granulosus pyruvate kinase 0.0022 0.0099 0.0099
Loa Loa (eye worm) glycerol 3 phosphate dehydrogenase 0.0007 0.0006 0.0006
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0195 0.1183 0.1916
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0077 0.0125
Loa Loa (eye worm) hypothetical protein 0.0008 0.0016 0.0017
Trichomonas vaginalis glycerol-3-phosphate dehydrogenase, putative 0.0007 0.0006 0.0029
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0029 0.0144 0.0144
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0091 0.0532 0.0532
Leishmania major cathepsin L-like protease 0.0018 0.0079 0.0079
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0067 0.0067
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0135 0.0219
Plasmodium falciparum BRIX domain, putative 0.0163 0.0984 0.1355
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.017 0.0276
Brugia malayi galactokinase family protein 0.0007 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0012
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0091 0.0535 0.2687
Onchocerca volvulus 0.011 0.0655 0.2469
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0014 0.005 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0052
Echinococcus granulosus neuropeptide receptor 0.0015 0.006 0.006
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.0138 0.0828 0.134
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0055 0.031 0.031
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0012 0.0038 0.0061
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0047 0.0261 0.0261
Brugia malayi 6-phosphofructokinase 0.0078 0.0454 0.047
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0217 0.1324 0.3486
Mycobacterium leprae conserved hypothetical protein 0.0007 0.0011 0.0013
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.116 0.7227 1
Trypanosoma brucei unspecified product 0.0037 0.0194 0.0194
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0056 0.0315 0.0315
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0021 0.0096 0.0574
Schistosoma mansoni galactokinase 0.0007 0.0008 0.0008
Brugia malayi Protein cec-1. 0.002 0.0087 0.0091
Toxoplasma gondii 6-phosphofructokinase 0.0021 0.0096 0.0096
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0077 0.0077
Toxoplasma gondii ribonuclease HI protein 0.0007 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0087 0.0439
Leishmania major DNA polymerase eta, putative 0.0033 0.017 0.017
Leishmania major ATP-dependent phosphofructokinase 0.0078 0.0454 0.0454
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0104 0.0615 0.3086
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0025 0.012 0.0194
Schistosoma mansoni 6-phosphofructokinase 0.0078 0.0454 0.0454
Schistosoma mansoni hypothetical protein 0.0015 0.006 0.006
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0092 0.0541 0.0541
Entamoeba histolytica recQ family helicase, putative 0.0026 0.013 0.0773
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.005 0.005
Trypanosoma cruzi galactokinase-like protein, putative 0.0013 0.0047 0.0076
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0011 0.0011
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0025 0.0119 0.0123
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.0138 0.0828 0.134
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0217 0.1324 0.3487
Echinococcus multilocularis pyruvate kinase 0.0011 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0029 0.0144 0.0149
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0007 0.001 0.001
Treponema pallidum pyruvate carboxylase subunit B 0.0056 0.0315 0.3377
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.009 0.0528 0.0528
Chlamydia trachomatis endonuclease IV 0.0049 0.0273 0.078
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.006 0.006
Brugia malayi M-phase phosphoprotein, mpp8 0.011 0.0655 0.0679
Onchocerca volvulus 0.011 0.0655 0.2469
Mycobacterium ulcerans endonuclease IV 0.0049 0.0273 0.0708
Mycobacterium tuberculosis Probable reductase 0.0109 0.0645 0.1692
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0078 0.0454 0.1185
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.006 0.006
Onchocerca volvulus 0.0015 0.006 0.0208
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.006 0.0063
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0016 0.0016
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0067 0.0067
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0104 0.0615 0.3086
Brugia malayi regulator of G-protein signaling rgs-7 0.0014 0.005 0.0052
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0217 0.1324 0.3486
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.1603 1 1
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0091 0.0091
Brugia malayi Pre-SET motif family protein 0.0285 0.1746 0.1809
Leishmania major pyruvate kinase 0.0022 0.0099 0.0099
Leishmania major carboxylase, putative 0.0611 0.3787 0.3787
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0104 0.0615 0.3086
Echinococcus multilocularis regulator of G protein signaling 0.0014 0.005 0.005
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0217 0.1324 0.1324
Mycobacterium ulcerans phosphoglycerate kinase 0.0122 0.0731 0.1918
Leishmania major pyruvate kinase 0.0022 0.0099 0.0099
Schistosoma mansoni chromobox protein 0.002 0.0087 0.0087
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0055 0.031 0.031
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0067 0.0067
Trypanosoma cruzi acetyl-CoA carboxylase 0.0992 0.6177 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0087 0.0439
Chlamydia trachomatis phosphoglycerate kinase 0.0122 0.0731 0.2114
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.006 0.006
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0049 0.0273 0.0371
Schistosoma mansoni inositol monophosphatase 0.0012 0.0038 0.0038
Schistosoma mansoni phosphoglucomutase 0.0007 0.0008 0.0008
Echinococcus multilocularis phosphoglycerate kinase 1 0.0122 0.0731 0.0731
Plasmodium falciparum fructose-bisphosphate aldolase 0.0055 0.031 0.0421
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0011 0.0015
Plasmodium vivax hypothetical protein, conserved 0.0163 0.0984 0.1355
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0067 0.0067
Schistosoma mansoni transcription factor LCR-F1 0.0011 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0381 0.1912
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0067 0.0067
Entamoeba histolytica phosphofructokinase, putative 0.0078 0.0454 0.2708
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.006 0.006
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.013 0.013
Echinococcus multilocularis Polycystic kidney disease protein 0.0027 0.0132 0.0132
Echinococcus granulosus zinc finger protein 598 0.0162 0.0978 0.0978
Mycobacterium ulcerans error-prone DNA polymerase 0.0153 0.0923 0.2425
Leishmania major hypothetical protein, conserved 0.003 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.007 0.0401 0.0416
Brugia malayi larval opioid receptor 0.0015 0.006 0.0063
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0096 0.0125
Echinococcus granulosus chromatin regulatory protein sir2 0.0083 0.0483 0.0483
Schistosoma mansoni intermediate filament proteins 0.0017 0.0073 0.0073
Echinococcus multilocularis tumor protein p63 0.0098 0.0576 0.0576
Trypanosoma brucei acetyl-CoA carboxylase 0.1603 1 1
Schistosoma mansoni chromatin regulatory protein sir2 0.0083 0.0483 0.0483
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0036 0.0192 0.0192
Onchocerca volvulus 0.0007 0.0011 0.0019
Toxoplasma gondii biotin-requiring enzyme domain-containing protein 0.0056 0.0315 0.0315
Trypanosoma brucei phosphoglycerate kinase 0.0122 0.0731 0.0731
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0023 0.0111 0.018
Echinococcus granulosus 6 phosphofructokinase 0.0078 0.0454 0.0454
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0073 0.0421 0.0436
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0023 0.0109 0.0109
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.006 0.006
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0053 0.0296 0.0307
Schistosoma mansoni P2X receptor subunit 0.046 0.2841 0.2841
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0025 0.0122 0.0161
Loa Loa (eye worm) hypothetical protein 0.004 0.0212 0.022
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0645 0.1692
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0611 0.3787 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0049 0.0268 0.0434
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0051 0.0282 0.073
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) RGS-3 protein 0.0014 0.005 0.0052
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0217 0.1324 0.3486
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0056 0.0315 0.0511
Echinococcus multilocularis neuropeptide receptor 0.0015 0.006 0.006
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0138 0.0828 0.2175
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0127 0.0636
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0055 0.031 0.031
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.006 0.0063
Echinococcus multilocularis lamin dm0 0.0017 0.0073 0.0073
Treponema pallidum DNA polymerase III subunit alpha 0.0153 0.0923 1
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.006 0.0063
Echinococcus granulosus g protein coupled receptor 0.0015 0.006 0.006
Mycobacterium leprae Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog) 0.0011 0.0034 0.0075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0067 0.0109
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.006 0.006
Schistosoma mansoni terminal deoxycytidyl transferase 0.0053 0.0298 0.0298
Treponema pallidum NADH oxidase 0.0017 0.0067 0.0673
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.006 0.006
Giardia lamblia Sgs1 DNA helicase, putative 0.0025 0.0119 0.0711
Trichomonas vaginalis adenosine/guanosine diphosphatase, putative 0.0067 0.0381 0.1912
Giardia lamblia Sirtuin type 2 0.0025 0.0122 0.0727
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0039 0.021 0.021
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0104 0.0615 0.3668
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0012 0.0038 0.0038
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0225 0.0835
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0056 0.0315 0.0511
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.002 0.0087 0.0521
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.0144 0.0723
Echinococcus multilocularis orexin receptor type 2 0.0015 0.006 0.006
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0091 0.0535 0.0535
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0014 0.005 0.005
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0036 0.0192 0.0963
Loa Loa (eye worm) hypothetical protein 0.0027 0.0132 0.0137
Trichomonas vaginalis galactokinase, putative 0.0007 0.0008 0.0043
Brugia malayi Flap endonuclease-1 0.0019 0.0081 0.0084
Echinococcus multilocularis neuropeptide receptor 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0052
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0012 0.004 0.0047
Trichomonas vaginalis set domain proteins, putative 0.0324 0.1992 1
Brugia malayi 6-phosphofructokinase 0.0078 0.0454 0.047
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0008 0.0011 0.0015
Trypanosoma brucei ingi protein (ORF1) 0.0008 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0011 0.0036 0.0213
Schistosoma mansoni chromatin regulatory protein sir2 0.0091 0.0535 0.0535
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0011 0.003 0.0064
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0007 0.001 0.0016
Trypanosoma cruzi DNA polymerase kappa, putative 0.008 0.0466 0.0755
Trichomonas vaginalis glycerol-3-phosphate dehydrogenase, putative 0.0007 0.0006 0.0029
Echinococcus granulosus lipoxygenase domain containing protein 0.0027 0.0132 0.0132
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.006 0.006
Echinococcus granulosus RUN 0.0027 0.0132 0.0132
Schistosoma mansoni opsin-like receptor 0.0015 0.006 0.006
Trichomonas vaginalis galactokinase, putative 0.0007 0.0008 0.0043
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0027 0.0027
Mycobacterium ulcerans DNA polymerase IV 0.008 0.0466 0.1218
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0017 0.0073 0.0075
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) histone methyltransferase 0.001 0.0027 0.0028
Brugia malayi Muscleblind-like protein 0.0053 0.0296 0.0307
Schistosoma mansoni biogenic amine receptor 0.0015 0.006 0.006
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0611 0.3787 0.3787
Plasmodium falciparum phosphoglycerate kinase 0.0122 0.0731 0.1004
Onchocerca volvulus 0.0027 0.0132 0.0481
Loa Loa (eye worm) doublecortin family protein 0.0027 0.0132 0.0137
Giardia lamblia DINP protein human, muc B family 0.006 0.034 0.2028
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0012 0.0038 0.0084
Echinococcus granulosus glycerol 3 phosphate dehydrogenase NAD 0.0007 0.0006 0.0006
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0013 0.0045 0.015
Loa Loa (eye worm) hypothetical protein 0.0068 0.0392 0.0407
Plasmodium vivax glutathione reductase, putative 0.0048 0.0263 0.0356
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0078 0.0454 0.0454
Brugia malayi transcriptional regulator, Sir2 family protein 0.0025 0.0122 0.0126
Trypanosoma brucei dihydrolipoamide acetyltransferase E2 subunit, putative 0.0056 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0217 0.1324 0.3844
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Schistosoma mansoni phosphoglycerate kinase 0.0122 0.0731 0.0731
Echinococcus granulosus single minded 2 0.001 0.0029 0.0029
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0067 0.0339
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.006 0.006
Schistosoma mansoni loxhd1 0.0027 0.0132 0.0132
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0077 0.0077
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0096 0.0483
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0091 0.0535 0.2687
Brugia malayi follicle stimulating hormone receptor 0.0164 0.0989 0.1025
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0078 0.0454 0.0454
Mycobacterium ulcerans glutaminase 0.0087 0.0509 0.1332
Schistosoma mansoni rab6-interacting 0.0027 0.0132 0.0132
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0009 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0008 0.0011 0.0012
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0056 0.0315 0.0315
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0466 0.0466
Entamoeba histolytica recQ family DNA helicase 0.0013 0.0043 0.0257
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0217 0.1324 0.1324
Loa Loa (eye worm) hypothetical protein 0.0427 0.2636 0.2732
Schistosoma mansoni hypothetical protein 0.002 0.0087 0.0087
Mycobacterium ulcerans pyruvate kinase 0.0022 0.0099 0.0246
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0217 0.1324 0.1324
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0466 0.0466
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.002 0.0087 0.0087
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0077 0.0077
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.006 0.006
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0045 0.0245 0.0397
Trypanosoma brucei DNA polymerase IV, putative 0.008 0.0466 0.0466
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.0144 0.0233
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.006 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.006 0.006
Echinococcus multilocularis dna polymerase eta 0.007 0.0401 0.0401
Loa Loa (eye worm) hypothetical protein 0.0014 0.005 0.0052
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0067 0.0067
Plasmodium falciparum apyrase, putative 0.0067 0.0381 0.0519
Echinococcus multilocularis chromobox protein 1 0.0062 0.035 0.035
Schistosoma mansoni neuropeptide receptor 0.0015 0.006 0.006
Mycobacterium ulcerans hypothetical protein 0.0013 0.0045 0.0105
Schistosoma mansoni rab6-interacting 0.0027 0.0132 0.0132
Echinococcus granulosus hypothetical protein 0.0015 0.006 0.006
Brugia malayi bHLH-PAS transcription factor 0.001 0.0029 0.003
Echinococcus multilocularis Regulator of G protein signaling 20 0.0014 0.005 0.005
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.006 0.006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.006 0.006
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0138 0.0828 0.2175
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Echinococcus multilocularis dnaJ subfamily B 0.0249 0.1521 0.1521
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0067 0.0402
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Trypanosoma cruzi nucleoside phosphatase, putative 0.0098 0.0579 0.0937
Loa Loa (eye worm) hypothetical protein 0.0122 0.0731 0.0758
Brugia malayi hypothetical protein 0.0047 0.026 0.0269
Schistosoma mansoni z-protein (S1r protein) 0.0014 0.005 0.005
Entamoeba histolytica phosphofructokinase, putative 0.0078 0.0454 0.2708
Loa Loa (eye worm) pyruvate kinase 0.0022 0.0099 0.0102
Schistosoma mansoni blooms syndrome DNA helicase 0.0013 0.0043 0.0043
Brugia malayi A-kinase anchor protein 10, precursor 0.0014 0.005 0.0052
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.006 0.006
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0023 0.0111 0.0662
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0025 0.0119 0.0119
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0078 0.0454 0.0454
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.0144 0.0144
Echinococcus multilocularis fmrfamide receptor 0.0015 0.006 0.006
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0036 0.0192 0.0192
Brugia malayi Heterochromatin protein 1 0.0062 0.035 0.0363
Entamoeba histolytica hypothetical protein 0.0011 0.0036 0.0213
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0273 0.1675 1
Schistosoma mansoni chromatin regulatory protein sir2 0.0036 0.0192 0.0192
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.006 0.006
Loa Loa (eye worm) brix domain-containing protein 0.0163 0.0984 0.102
Trypanosoma brucei glycerol-3-phosphate dehydrogenase [NAD+], glycosomal 0.0007 0.0006 0.0006
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Schistosoma mansoni opsin-like receptor 0.0015 0.006 0.006
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0087 0.0439
Brugia malayi CXXC zinc finger family protein 0.0028 0.0137 0.0142
Chlamydia trachomatis biotin carboxylase 0.0554 0.3435 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.006 0.006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0027 0.0132 0.0132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0104 0.0615 0.3086
Leishmania major DNA polymerase kappa, putative 0.0017 0.0068 0.0068
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0104 0.0615 0.3086
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.006 0.006
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0012 0.0038 0.0038
Schistosoma mansoni lipoxygenase 0.0113 0.0668 0.0668
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0053 0.0298 0.0298
Trypanosoma cruzi DNA polymerase kappa, putative 0.008 0.0466 0.0755
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0041 0.0223 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0087 0.0439
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0029 0.0144 0.0149
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0145 0.0235
Echinococcus granulosus dna polymerase eta 0.007 0.0401 0.0401
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0023 0.0111 0.0111
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0025 0.0122 0.0122
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0012 0.0038 0.0038
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0122 0.0731 0.367
Echinococcus multilocularis cpg binding protein 0.0029 0.0147 0.0147
Loa Loa (eye worm) helicase 0.002 0.0087 0.0091
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.006 0.006
Entamoeba histolytica hypothetical protein 0.002 0.0087 0.0521
Plasmodium falciparum carbamoyl phosphate synthetase 0.0138 0.0828 0.1139
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0077 0.0389
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0161 0.0972 0.0972
Trypanosoma brucei unspecified product 0.0401 0.2477 0.2477
Onchocerca volvulus 0.0015 0.006 0.0208
Echinococcus multilocularis Ankyrin 0.0009 0.0022 0.0022
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0019 0.0083 0.0107
Mycobacterium ulcerans hypothetical protein 0.0017 0.0068 0.0164
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0009 0.0022 0.0022
Schistosoma mansoni ATP-diphosphohydrolase 1 0.0067 0.0381 0.0381
Echinococcus granulosus peter pan 0.0163 0.0984 0.0984
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.006 0.006
Echinococcus multilocularis expressed protein 0.0024 0.0114 0.0114
Trypanosoma brucei unspecified product 0.0074 0.0424 0.0424
Leishmania major 4-coumarate:coa ligase-like protein 0.0008 0.0011 0.0011
Toxoplasma gondii pyruvate kinase PyKII 0.0011 0.0033 0.0033
Mycobacterium ulcerans hypothetical protein 0.0132 0.0788 0.2068
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0014 0.005 0.0052
Brugia malayi RNase H family protein 0.0007 0.0008 0.0008
Brugia malayi Doublecortin family protein 0.0027 0.0132 0.0137
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0077 0.0099
Trypanosoma brucei RNA helicase, putative 0.0026 0.0129 0.0129
Schistosoma mansoni DNA polymerase eta 0.007 0.0401 0.0401
Loa Loa (eye worm) glutaminase 2 0.0087 0.0509 0.0528
Trypanosoma brucei dihydrolipoamide branched chain transacylase, putative 0.0056 0.0315 0.0315
Schistosoma mansoni chromobox protein 0.0062 0.035 0.035
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0091 0.0535 0.3194
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.008 0.0466 0.2341
Treponema pallidum phosphoglycerate kinase 0.0122 0.0731 0.7908
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0466 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0003 0.0016
Brugia malayi glutathione reductase 0.0048 0.0263 0.0272
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0611 0.3787 0.3787
Trypanosoma brucei pyruvate dehydrogenase complex E3 binding protein, putative 0.0056 0.0315 0.0315
Giardia lamblia Flap structure-specific endonuclease 0.0019 0.0081 0.0485
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.005 0.005
Echinococcus granulosus fmrfamide receptor 0.0015 0.006 0.006
Echinococcus multilocularis p2X purinoceptor 4 0.046 0.2841 0.2841
Echinococcus multilocularis survival motor neuron protein 1 0.0068 0.0392 0.0392
Leishmania major sir2-family protein-like protein 0.0025 0.0122 0.0122
Echinococcus multilocularis allatostatin A receptor 0.0015 0.006 0.006
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0611 0.3787 0.3787
Schistosoma mansoni opsin-like receptor 0.0015 0.006 0.006
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0025 0.012 0.012
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0007 0.0011 0.0013
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0078 0.0454 0.0454
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0055 0.031 0.0321
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Trypanosoma cruzi major cysteine proteinase, putative 0.0015 0.0055 0.0089
Brugia malayi regulator of G-protein signaling egl-10 0.0014 0.005 0.0052
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.006 0.006
Echinococcus granulosus inositol monophosphatase 1 0.0012 0.0038 0.0038
Echinococcus multilocularis sex peptide receptor 0.0015 0.006 0.006
Echinococcus granulosus somatostatin receptor 0.0015 0.006 0.006
Onchocerca volvulus 0.0022 0.0102 0.0366
Brugia malayi Dopamine receptor protein 1 0.0015 0.006 0.0063
Onchocerca volvulus Ribonuclease H1 homolog 0.0007 0.0008 0.0009
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Echinococcus granulosus protein arginine methyltransferase 0.0019 0.0086 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.006 0.006
Leishmania major phosphoglycerate kinase B, cytosolic 0.0122 0.0731 0.0731
Entamoeba histolytica hypothetical protein, conserved 0.0025 0.0122 0.0727
Loa Loa (eye worm) pyruvate kinase-PB 0.0015 0.0058 0.006
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0036 0.0192 0.0311
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.0144 0.0723
Echinococcus granulosus chromobox protein 1 0.0062 0.035 0.035
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0011 0.0012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0011 0.0015
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0083 0.0483 0.2427
Echinococcus granulosus Chromo domain 0.002 0.0087 0.0087
Onchocerca volvulus 0.0027 0.0132 0.0481
Onchocerca volvulus 0.0015 0.006 0.0208
Echinococcus granulosus survival motor neuron protein 1 0.0068 0.0392 0.0392
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0056 0.0315 0.0315
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0096 0.0264
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0033 0.0173 0.028
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0014 0.005 0.005
Echinococcus granulosus intermediate filament protein 0.0017 0.0073 0.0073
Mycobacterium ulcerans branched-chain alpha-keto acid dehydrogenase subunit E2 0.0056 0.0315 0.0819
Schistosoma mansoni hypothetical protein 0.0249 0.1521 0.1521
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0041 0.0223 0.0223
Echinococcus multilocularis transcription factor Dp 1 0.0052 0.029 0.029
Entamoeba histolytica hypothetical protein 0.002 0.0087 0.0521
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0077 0.008
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0025 0.0119 0.0119
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0077 0.019
Schistosoma mansoni cellular tumor antigen P53 0.0014 0.0053 0.0053
Mycobacterium ulcerans hypothetical protein 0.0056 0.0315 0.0819
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0003 0.0016
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0067 0.007
Echinococcus multilocularis L aminoadipate semialdehyde 0.0026 0.013 0.013
Trypanosoma cruzi DNA polymerase kappa, putative 0.008 0.0466 0.0755
Schistosoma mansoni neuropeptide receptor 0.0015 0.006 0.006
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0083 0.0483 0.0483
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.006 0.0063
Schistosoma mansoni neuropeptide receptor 0.0015 0.006 0.006
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.009 0.0528 0.0528
Brugia malayi ORL1-like opioid receptor 0.0015 0.006 0.0063
Schistosoma mansoni peter pan-related 0.0163 0.0984 0.0984
Brugia malayi G-protein coupled receptor 0.0015 0.006 0.0063
Loa Loa (eye worm) heterochromatin protein 1 0.0062 0.035 0.0363
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.002 0.0087 0.0087
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0122 0.0731 0.1183
Trichomonas vaginalis glycerol-3-phosphate dehydrogenase, putative 0.0007 0.0006 0.0029
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0043 0.0043
Brugia malayi CHD4 protein 0.0021 0.0097 0.0101
Trypanosoma brucei phosphoglycerate kinase 0.0045 0.0245 0.0245
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0021 0.0096 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.005 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0381 0.1912
Trypanosoma cruzi peter pan protein, putative 0.0163 0.0984 0.1593
Toxoplasma gondii Nucleoside-diphosphatase 0.0067 0.0381 0.0381
Echinococcus granulosus phosphoglycerate kinase 1 0.0122 0.0731 0.0731
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0067 0.0067
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.006 0.006
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0611 0.3787 1
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0022 0.0099 0.0246
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0067 0.0381 0.1912
Trypanosoma cruzi galactokinase, putative 0.0015 0.006 0.0097
Onchocerca volvulus 0.0026 0.013 0.0472
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.006 0.006
Echinococcus multilocularis bloom syndrome protein 0.0033 0.017 0.017
Toxoplasma gondii carbamoylphosphate synthetase 0.0138 0.0828 0.0828
Echinococcus multilocularis dna polymerase kappa 0.008 0.0466 0.0466
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.006 0.006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0011 0.0036 0.0036
Mycobacterium ulcerans DNA polymerase IV 0.008 0.0466 0.1218
Schistosoma mansoni P2X receptor subunit 0.046 0.2841 0.2841
Leishmania major carbamoyl-phosphate synthase, putative 0.0138 0.0828 0.0828
Loa Loa (eye worm) hypothetical protein 0.0008 0.0014 0.0015
Leishmania major silent information regulator 2, putative 0.0083 0.0483 0.0483
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.006 0.006
Echinococcus multilocularis zinc finger protein 598 0.0162 0.0978 0.0978
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.034 0.034
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0645 0.1692
Onchocerca volvulus 0.0015 0.006 0.0208
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0217 0.1324 0.2143
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0138 0.0828 0.1139
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0302 0.0302
Schistosoma mansoni ankyrin 23/unc44 0.0009 0.0022 0.0022
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0055 0.031 0.0421
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0009 0.0022 0.0022
Trichomonas vaginalis glycerol-3-phosphate dehydrogenase, putative 0.0007 0.0006 0.0029
Plasmodium falciparum DNA repair protein REV1, putative 0.0017 0.0068 0.0086
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.009 0.0528 0.0547
Schistosoma mansoni hypothetical protein 0.0015 0.006 0.006
Echinococcus multilocularis pyruvate kinase 0.0022 0.0099 0.0099
Schistosoma mansoni lamin 0.0017 0.0073 0.0073
Trypanosoma cruzi DNA polymerase eta, putative 0.007 0.0401 0.0649
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0029 0.0144 0.0144
Entamoeba histolytica hypothetical protein 0.0014 0.005 0.03
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide acyltransferase E2 component 0.0056 0.0315 0.0819
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.006 0.006
Trypanosoma brucei nucleoside phosphatase, putative 0.0098 0.0579 0.0579
Leishmania major 4-coumarate:coa ligase-like protein 0.0008 0.0011 0.0011
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0029 0.0144 0.086
Loa Loa (eye worm) hypothetical protein 0.0056 0.0315 0.0327
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0021 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0067 0.0085
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.009 0.0528 0.0528
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0056 0.0315 0.0327
Plasmodium falciparum pyruvate kinase 0.0022 0.0099 0.0129
Echinococcus granulosus orexin receptor type 2 0.0015 0.006 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0466 0.0466
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.006 0.0208
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.006 0.0063
Chlamydia trachomatis pyruvate kinase 0.0022 0.0099 0.0271
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0007 0.001 0.001
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0055 0.031 0.031
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0011 0.0036 0.0036
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0027 0.0135 0.0135
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0067 0.0109
Leishmania major fructose-1,6-bisphosphate aldolase 0.0055 0.031 0.031
Schistosoma mansoni myosin xvIII 0.0015 0.006 0.006
Echinococcus multilocularis beta adrenergic receptor kinase 0.0014 0.005 0.005
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.0007 0.0006 0.0006
Brugia malayi Valyl-tRNA synthetase 0.002 0.0087 0.0091
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0078 0.0454 0.0735
Brugia malayi PAS domain containing protein 0.0014 0.0052 0.0054
Echinococcus multilocularis netrin receptor unc 5 0.0009 0.0022 0.0022
Echinococcus multilocularis pyruvate kinase 0.0011 0.0033 0.0033
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0056 0.0315 0.0511
Toxoplasma gondii pyruvate carboxylase 0.0611 0.3787 0.3787
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0119 0.0119
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0067 0.018
Echinococcus granulosus Polycystic kidney disease protein 0.0027 0.0132 0.0132
Schistosoma mansoni rotamase 0.0024 0.0114 0.0114
Plasmodium vivax pyruvate kinase, putative 0.0022 0.0099 0.0129
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.006 0.006
Giardia lamblia Transcriptional regulator, Sir2 family 0.0036 0.0192 0.1145
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0138 0.0828 0.0828
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0611 0.3787 1
Entamoeba histolytica hypothetical protein 0.0007 0.0011 0.0063
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.006 0.006
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0021 0.0097 0.0097
Onchocerca volvulus 0.001 0.0029 0.0089
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0049 0.0273 0.0371
Echinococcus multilocularis Chromobox protein 3 0.002 0.0087 0.0087
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0055 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Entamoeba histolytica acyl-CoA synthetase, putative 0.0008 0.0011 0.0067
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0055 0.031 0.031
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0007 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0067 0.0163
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0263 0.0356
Trypanosoma brucei DNA polymerase IV, putative 0.0074 0.0424 0.0424
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0217 0.1324 0.1324
Loa Loa (eye worm) hypothetical protein 0.0025 0.012 0.0124
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0019 0.0086 0.0111
Loa Loa (eye worm) 6-phosphofructokinase 0.0078 0.0454 0.047
Brugia malayi Phosphoglycerate kinase 0.0045 0.0245 0.0254
Trypanosoma brucei pyruvate kinase 1 0.0022 0.0099 0.0099
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0012 0.0038 0.0061
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.002 0.009 0.0454
Onchocerca volvulus Netrin receptor homolog 0.0009 0.0022 0.0062
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0055 0.031 0.031
Trichomonas vaginalis flap endonuclease-1, putative 0.0019 0.0081 0.0408
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0079 0.0079
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0029 0.0144 0.0144
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0024 0.0114 0.0119
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0285 0.1746 0.1809
Echinococcus granulosus chromobox protein 1 0.0062 0.035 0.035
Brugia malayi Pyruvate kinase, M2 isozyme 0.0022 0.0099 0.0102
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0067 0.0381 0.0381
Brugia malayi Inositol-1 0.0012 0.0038 0.0039
Echinococcus multilocularis inositol monophosphatase 1 0.0012 0.0038 0.0038
Schistosoma mansoni DNA helicase recq1 0.0025 0.0119 0.0119
Trichomonas vaginalis galactokinase, putative 0.0007 0.0008 0.0043
Echinococcus granulosus ribonuclease H1 0.0007 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0236 0.0236
Loa Loa (eye worm) transcriptional regulator 0.0025 0.0122 0.0126
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.006 0.006
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.116 0.7227 1
Schistosoma mansoni P2X receptor subunit 0.0247 0.1513 0.1513
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0056 0.0315 0.0903
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0003 0.0016
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.006 0.006
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0083 0.0483 0.2884
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0011 0.0015
Giardia lamblia Pyruvate kinase 0.0022 0.0099 0.0588
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.006 0.006
Brugia malayi hypothetical protein 0.0015 0.006 0.0063
Plasmodium vivax nucleoside-diphosphatase mig-23, putative 0.0067 0.0381 0.0519
Echinococcus multilocularis ribonuclease H1 0.0007 0.0008 0.0008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0008 0.0011 0.0067
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0049 0.0268 0.0268
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0611 0.3787 0.3787
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0041 0.0223 0.0223
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0056 0.0315 0.0511
Echinococcus multilocularis muscleblind protein 1 0.0053 0.0296 0.0296
Toxoplasma gondii endonuclease IV APN 0.0049 0.0273 0.0273
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0045 0.0245 0.0397
Toxoplasma gondii glycerol-3-phosphate dehydrogenase (gpdh), putative 0.0007 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0003 0.0016
Trichomonas vaginalis DNA helicase recq, putative 0.0033 0.017 0.0852
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0721 0.1893
Entamoeba histolytica recQ family helicase, putative 0.0012 0.004 0.0239
Brugia malayi hypothetical protein 0.0027 0.0132 0.0137
Loa Loa (eye worm) hypothetical protein 0.0026 0.013 0.0135
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.002 0.0087 0.0087
Schistosoma mansoni chromatin regulatory protein sir2 0.0025 0.0122 0.0122
Brugia malayi Phosphoglycerate kinase 0.0122 0.0731 0.0758
Schistosoma mansoni single-minded 0.0014 0.0052 0.0052
Echinococcus multilocularis protein arginine methyltransferase 0.0019 0.0086 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.011 0.0655 0.0679
Loa Loa (eye worm) hypothetical protein 0.0053 0.0296 0.0307
Trichomonas vaginalis rotamase, putative 0.0023 0.0111 0.0557
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0721 0.1893
Mycobacterium tuberculosis Conserved hypothetical protein 0.0053 0.0298 0.0774
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0083 0.0482 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0087 0.0439
Echinococcus granulosus netrin receptor unc 5 0.0009 0.0022 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0079 0.0129
Brugia malayi SET domain containing protein 0.0022 0.0101 0.0104
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0127 0.0636
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0055
Echinococcus granulosus regulator of G protein signaling 7 0.0014 0.005 0.005
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0096 0.0125
Loa Loa (eye worm) transcriptional regulator 0.0083 0.0483 0.0501
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0049 0.0273 0.0708
Giardia lamblia Peter pan protein 0.0163 0.0984 0.5875
Leishmania major glycerol-3-phosphate dehydrogenase [NAD ], glycosomal 0.0007 0.0006 0.0006
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0067 0.0381 0.0381
Echinococcus multilocularis somatostatin receptor 0.0015 0.006 0.006
Echinococcus granulosus p2X purinoceptor 4 0.046 0.2841 0.2841
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Leishmania major DNA polymerase kappa, putative 0.006 0.034 0.034
Schistosoma mansoni inositol monophosphatase 0.0012 0.0038 0.0038
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0007 0.0011 0.0013
Brugia malayi hypothetical protein 0.0027 0.0132 0.0137
Echinococcus multilocularis N acetylgalactosamine kinase 0.0007 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0047 0.026 0.0269
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0013 0.0045 0.0047
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0011 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0144 0.0723
Schistosoma mansoni regulator of G protein signaling 0.0014 0.005 0.005
Brugia malayi G protein-coupled receptor 0.0015 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0027 0.0132 0.0137
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0023 0.0111 0.018
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0078 0.0454 0.0471
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0067 0.0109
Brugia malayi ImpB/MucB/SamB family protein 0.0053 0.0298 0.0309
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0025 0.0122 0.0612
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.0063
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0611 0.3787 0.3787
Trypanosoma cruzi dihydrolipoamide acetyltransferase, putative 0.0056 0.0315 0.0511

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 30 mins by spectrofluorimetry ChEMBL. 22386984
IC50 (binding) = 290 uM Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 30 mins by spectrofluorimetry ChEMBL. 22386984

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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