TDR Targets

Basic information

Technical information

TDR Targets ID: 1624630
Name: N-[3-(4-aminobutylamino)propyl]-2-[2-(2-amino ethyl)-5-chloro-1,3-thiazol-4-yl]-1,3-thiazol e-4-carboxamide
MW: 416.992 | Formula: C16H25ClN6OS2
H donors: 4 H acceptors: 3 LogP: 1.31 Rotable bonds: 13
Rule of 5 violations (Lipinski): 1
SMILES: NCCCCNCCCNC(=O)c1csc(n1)c1nc(sc1Cl)CCN
InChi: 1S/C16H25ClN6OS2/c17-14-13(23-12(26-14)4-6-19)16-22-11(10-25-16)15(24)21-9-3-8-20-7-2-1-5-18/h10,20H,1-9,18-19H2,(H,21,24)
InChiKey: KKFJFYWIRNILQS-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

N-[3-(4-aminobutylamino)propyl]-2-[2-(2-aminoethyl)-5-chloro-thiazol-4-yl]thiazole-4-carboxamide
N-[3-(4-aminobutylamino)propyl]-2-[2-(2-aminoethyl)-5-chloro-4-thiazolyl]-4-thiazolecarboxamide
AIDS-141081
AIDS141081
NSC655424
[2,4'-Bithiazole]-4-carboxamide, N-[3-[(4-aminobutyl)amino]propyl]-2'-(2-aminoethyl)-5'-chloro-
NCI60_019218

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	AGC/PKG protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	AGC protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	cGMP-dependent protein kinase	0.0028	0.0036	0.5
Plasmodium falciparum	cdc2-related protein kinase 5	0.0028	0.0036	0.5
Mycobacterium ulcerans	serine/threonine-protein kinase transcriptional regulatory protein PknK_3	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/PIM protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Echinococcus granulosus	lamin	0.0031	0.0048	0.0012
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	hypothetical protein	0.0028	0.0036	0.0036
Plasmodium falciparum	protein kinase 1	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1/TTBK protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Brugia malayi	cyclin-dependent kinase 7 homolog	0.0028	0.0036	0.0036
Loa Loa (eye worm)	STE/STE11/MEKK4 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AUR protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Brugia malayi	hypothetical protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	serine/threonine protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	serine/threonine protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	serine/threonine-protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Brugia malayi	Egg laying defective protein 4	0.0028	0.0036	0.0036
Mycobacterium ulcerans	membrane-anchored serine/threonine-protein kinase	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-like	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CAMK/CAMKL/CHK1 protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0028	0.0036	0.0036
Schistosoma mansoni	serine/threonine protein kinase	0.3051	1	1
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/TTBK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	ankyrin repeat protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	TKL/LISK/TESK protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CAMK/CAMKL/LKB protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/CDK/CDK10 protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0028	0.0036	0.0036
Trichomonas vaginalis	CMGC family protein kinase	0.3051	1	1
Loa Loa (eye worm)	CMGC/DYRK/DYRK2 protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Plasmodium falciparum	EKC/KEOPS complex subunit BUD32	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/CDK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/MAPK protein kinase	0.0028	0.0036	0.0036
Echinococcus multilocularis	musashi	0.0031	0.0048	0.0012
Entamoeba histolytica	casein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	SCY1 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Plasmodium falciparum	NIMA related kinase 4	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK-like	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	Rab GTPase activating protein, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	tyrosine kinase-like protein, putative	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	p21-activated kinase	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	hypothetical protein	0.0028	0.0036	0.0036
Plasmodium vivax	SET domain protein, putative	0.0035	0.0059	1
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Loa Loa (eye worm)	WEE protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Echinococcus multilocularis	lamin	0.0031	0.0048	0.0012
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Brugia malayi	FMRFamide related peptide family protein	0.0028	0.0036	0.0036
Chlamydia trachomatis	serine/threonine protein kinase	0.0028	0.0036	0.5
Loa Loa (eye worm)	TKL/MLK/LZK protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	haspin protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	STE/STE7 protein kinase	0.0028	0.0036	0.0036
Echinococcus granulosus	histone lysine methyltransferase setb	0.0035	0.0059	0.0023
Loa Loa (eye worm)	CAMK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	STE/STE20/PAKA protein kinase	0.0028	0.0036	0.0036
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0035	0.0059	0.0023
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Entamoeba histolytica	casein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	ULK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	IKK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain	0.0028	0.0036	0.0036
Mycobacterium ulcerans	serine/threonine-protein kinase PknG	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Echinococcus multilocularis	mitogen activated protein kinase	0.3051	1	1
Plasmodium falciparum	calcium/calmodulin-dependent protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	calcium-dependent protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	VPS15 protein kinase	0.0028	0.0036	0.0036
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0035	0.0059	0.0023
Loa Loa (eye worm)	BUB protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/TTBKL protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/MAPK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	STE/STE20/MSN protein kinase	0.0028	0.0036	0.0036
Mycobacterium leprae	PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE L PKNL (PROTEIN KINASE L) (STPK L)	0.0028	0.0036	0.5
Giardia lamblia	Kinase	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	STE/STE11/ASK protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	calcium/calmodulin-dependent protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein, conserved	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/RSK/MSK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Brugia malayi	serine/threonine-protein kinase 6	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Trichomonas vaginalis	CMGC family protein kinase	0.3051	1	1
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	cAMP-dependent protein kinase catalytic subunit	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	map kinase activated protein kinase protein 2	0.0028	0.0036	0.0036
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0241	0.0739	0.0739
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0046	0.0046
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Trichomonas vaginalis	CMGC family protein kinase	0.3051	1	1
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	0.3051	1	1
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	NEK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	cell division protein kinase 2, putative	0.0028	0.0036	0.5
Brugia malayi	protein unc-22	0.0028	0.0036	0.0036
Brugia malayi	Serine/threonine-protein kinase C05D10.2 in chromosome III	0.0028	0.0036	0.0036
Mycobacterium ulcerans	Ser/Thr protein kinase	0.0028	0.0036	0.5
Entamoeba histolytica	serine/threonine-protein kinase, putative	0.0028	0.0036	0.5
Trypanosoma brucei	mitogen activated protein kinase 4, putative	0.3051	1	1
Brugia malayi	cyclin-dependent kinase 9	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	NEK/NEK6 protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	NIMA related kinase 2	0.0028	0.0036	0.5
Loa Loa (eye worm)	serine/threonine protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	ULK/ULK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Pctaire class cell cycle kinase protein 1	0.0028	0.0036	0.0036
Brugia malayi	Homeodomain interacting protein kinase protein 1	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	AGC/PKN protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Serine/threonine-protein kinase K06H7.1	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/VRK protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	calcium-dependent protein kinase 6	0.0028	0.0036	0.5
Entamoeba histolytica	serine/threonine-protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	cell division protein kinase 2, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/CAMKL/NUAK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	cyclin-dependent kinase protein, putative	0.0028	0.0036	0.5
Brugia malayi	TM2 domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	G protein-coupled receptor kinase 1	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine-protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	STE/STE20/MST protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CAMK/DAPK/DAPK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Neuronal symmetry protein 1	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase sperm-specific MAP kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Echinococcus granulosus	mitogen activated protein kinase 3	0.3051	1	1
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	TKL/IRAK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CAMK/PIM protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase c protein 2	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	protein kinase 6	0.0028	0.0036	0.5
Onchocerca volvulus		0.0031	0.0048	0.0146
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-like	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Trichomonas vaginalis	harmonin-interacting ankyrin-repeat containing protein (harp), sans, putative	0.0028	0.0036	0.0000000047868
Brugia malayi	serine/threonine protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	EST embl\|AI107989\|AI107989 comes from the 3' UTR, putative	0.0028	0.0036	0.0036
Loa Loa (eye worm)	STE/STE20/PAKB protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Mycobacterium tuberculosis	Serine/threonine-protein kinase transcriptional regulatory protein PknK (protein kinase K) (STPK K)	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0028	0.0036	0.0000000047868
Brugia malayi	Germinal center kinase family protein 1	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	Doublecortin family protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0048	0.0048
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CAMK/PIM protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/TRBL protein kinase	0.0028	0.0036	0.0036
Brugia malayi	oxidative-stress responsive 1	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	0.3051	1	1
Loa Loa (eye worm)	NAK/MPSK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	plk/plk-unclassified protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/CK1/CK1-A protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Dual specificity mitogen-activated protein kinase kinase 7. -TRUNCATED-	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase KIN	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/MAST/MAST protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	STE/STE20/STLK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	WNK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine-protein kinase, putative	0.0028	0.0036	0.5
Leishmania major	mitogen activated protein kinase, putative,map kinase, putative	0.3051	1	1
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Brugia malayi	p21/Cdc42/Rac1-activated kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Onchocerca volvulus		0.0274	0.0848	1
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-GL-like	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CMGC/CDK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	cmgc/cdk/pitslre protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	AGC/NDR protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Ser/Thr kinase.	0.0028	0.0036	0.0036
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/RSK/RSK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	mitogen-activated protein kinase	0.0028	0.0036	0.5
Loa Loa (eye worm)	CAMK/TSSK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Cell division protein kinase 2	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	phosphoinositide-dependent protein kinase I	0.0028	0.0036	0.0036
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	TKL/STKR/TYPE2 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	serine/threonine protein kinase STE20, putative	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	serine/threonine-protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Stress-activated protein kinase jnk-1	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Brugia malayi	serine/threonine protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/DAPK/DAPK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	STE/STE7/MEK7 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	cell division control protein 2 homolog	0.0028	0.0036	0.0036
Brugia malayi	hypothetical protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Mycobacterium tuberculosis	Probable transmembrane serine/threonine-protein kinase I PknI (protein kinase I) (STPK I) (phosphorylase B kinase kinase) (hydro	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/DYRK/PRP4 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	STE/STE7/MEK3 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/RCK/MAK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Mycobacterium ulcerans	transmembrane serine/threonine-protein kinase PknQ	0.0028	0.0036	0.5
Giardia lamblia	Kinase, STE STE20	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Plasmodium falciparum	eukaryotic translation initiation factor 2-alpha kinase	0.0028	0.0036	0.5
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0033	0.0055	0.0019
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	STE/STE7/MEK1 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Schistosoma mansoni	intermediate filament proteins	0.0031	0.0048	0.0012
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Brugia malayi	probable protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Brugia malayi	PRKD2 protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/CK2 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/CDK/CDK4 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/DYRK/HIPK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Mycobacterium tuberculosis	Serine/threonine-protein kinase PknG (protein kinase G) (STPK G)	0.0028	0.0036	0.5
Loa Loa (eye worm)	CAMK/PSK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Calcium/calmodulin-dependent serine/threonine-protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Serine/threonine-protein kinase C07A9.3	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/CDK/CDK5 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	serine/threonine-protein kinase plk-2	0.0028	0.0036	0.0036
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Mycobacterium ulcerans	serine/threonine-protein kinase PknF_2	0.0028	0.0036	0.5
Brugia malayi	intracellular kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	hypothetical protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/MAPK/P38 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/PDK1 protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	protein kinase 2	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.3051	1	1
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0028	0.0036	0.5
Schistosoma mansoni	lamin	0.0031	0.0048	0.0012
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	cell division control protein 2 homolog	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	casein kinase I isoform delta, putative	0.0028	0.0036	0.5
Plasmodium falciparum	glycogen synthase kinase 3	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase with WD repeats	0.0028	0.0036	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	glycogen synthase kinase	0.0028	0.0036	0.0036
Brugia malayi	calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/CASK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Trichomonas vaginalis	CMGC family protein kinase	0.3051	1	1
Brugia malayi	Variant SH3 domain containing protein	0.0028	0.0036	0.0036
Leishmania major	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	0.3051	1	1
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/YANK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Loa Loa (eye worm)	NAK/GAK protein kinase	0.0028	0.0036	0.0036
Onchocerca volvulus		0.0031	0.0048	0.0146
Loa Loa (eye worm)	STE/STE7/MEK4 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	PEK/PEK protein kinase	0.0028	0.0036	0.0036
Onchocerca volvulus		0.0035	0.0059	0.0282
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Mitogen-activated protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Plasmodium falciparum	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Serine/threonine-protein kinase SULU	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, CMGC MAPK	0.3051	1	1
Plasmodium falciparum	cdc2-related protein kinase 4	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0059	0.0059
Loa Loa (eye worm)	CMGC/CDK/CDK9 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Schistosoma mansoni	lamin	0.0031	0.0048	0.0012
Brugia malayi	serine/threonine-protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	TTK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/PHK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	calcium-dependent protein kinase 2, putative	0.0028	0.0036	0.5
Mycobacterium ulcerans	Ser/Thr protein kinase	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	Dual specificity mitogen-activated protein kinase kinase 7. -TRUNCATED-	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Plasmodium falciparum	mitogen-activated protein kinase 2	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1/TTBKL protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CAMK/PKD protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CAMK/TSSK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	STE/STE20/PAKA protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	STE/STE20/YSK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine-protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	cell division control protein 2 homolog	0.0028	0.0036	0.0036
Plasmodium falciparum	cdc2-related protein kinase 3	0.0028	0.0036	0.5
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/PKA protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Dual-specificity tyrosine-phosphorylation regulated kinase 2	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase , putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/MAPK/JNK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	RWD domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Brugia malayi	Serine/threonine-protein kinase K06H7.1	0.0028	0.0036	0.0036
Trichomonas vaginalis	set domain proteins, putative	0.0274	0.0848	0.0816
Brugia malayi	hypothetical protein	0.0028	0.0036	0.0036
Brugia malayi	STE20-like kinase MST	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	NEK/NEK8 protein kinase	0.0028	0.0036	0.0036
Mycobacterium ulcerans	serine/threonine-protein kinase transcriptional regulatory protein PknK_2	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	putative serine/threonine kinase SADA gamma	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Entamoeba histolytica	casein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Mycobacterium tuberculosis	Anchored-membrane serine/threonine-protein kinase PknF (protein kinase F) (STPK F)	0.0028	0.0036	0.5
Toxoplasma gondii	CMGC kinase, MAPK family (ERK) MAPK-1	0.3051	1	1
Plasmodium falciparum	NIMA related kinase 1	0.0028	0.0036	0.5
Entamoeba histolytica	cell division protein kinase 2, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK-like	0.0028	0.0036	0.0000000047868
Brugia malayi	Serine/threonine-protein kinase F42G10.2	0.0028	0.0036	0.0036
Loa Loa (eye worm)	STE/STE7/MEK4 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	AGC/PKA protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Serine/threonine-protein kinase K06H7.1	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Mycobacterium tuberculosis	Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B)	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	serine/threonine-protein kinase PAK 7	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Plasmodium falciparum	tyrosine kinase-like protein, putative	0.0028	0.0036	0.5
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	SCY1 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0031	0.0048	0.0048
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine- protein kinase C823.03, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/RSK/P70 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	camk/mapkapk/mnk protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	CAMK/CAMKL/MELK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/CDK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	casein kinase 1, putative	0.0028	0.0036	0.5
Brugia malayi	Serine/threonine-protein kinase SULU	0.0028	0.0036	0.0036
Loa Loa (eye worm)	TKL/LRRK protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	C1-like domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	hypothetical protein	0.0028	0.0036	0.0036
Entamoeba histolytica	casein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CDC7 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Plasmodium falciparum	casein kinase 1	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/CK1/CK1-A protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	AGC/PDK1 protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Echinococcus multilocularis	mitogen activated protein kinase 3	0.3051	1	1
Loa Loa (eye worm)	CAMK/CAMKL/BRSK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	serine/threonine protein kinase 6	0.0028	0.0036	0.0036
Plasmodium falciparum	MO15-related protein kinase	0.0028	0.0036	0.5
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.3051	1	1
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/PKC/ALPHA protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	TKL/MLK/MLK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/DUAL protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	protein kinase 7	0.0028	0.0036	0.5
Loa Loa (eye worm)	CAMK/TSSK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	cAMP-dependent protein kinase catalytic subunit, putative	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK-like	0.0028	0.0036	0.0000000047868
Brugia malayi	cell division control protein 2 homolog	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Mycobacterium tuberculosis	Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A)	0.0028	0.0036	0.5
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.0028	0.0036	0.0036
Loa Loa (eye worm)	serine/threonine protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	NRBP protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/MAPK/NMO protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/PKD protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Mycobacterium ulcerans	Ser/Thr protein kinase	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Chlamydia trachomatis	serine/threonine-protein kinase	0.0028	0.0036	0.5
Entamoeba histolytica	cell division protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Entamoeba histolytica	casein kinase II alpha subunit, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/CDK/CDK7 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Pre-SET motif family protein	0.0035	0.0059	0.0059
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/NDR protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	cell division protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMK/CAMKL/AMPK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/TTBKL protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Brugia malayi	Dual specificity mitogen-activated protein kinase kinase mek-2	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine-protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	casein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	STE/STE20/KHS protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	TLK protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	RAC-beta serine/threonine protein kinase	0.0028	0.0036	0.5
Loa Loa (eye worm)	STE/STE11/MEKK2 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/CK1/CK1-D protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/MAPK/JNK protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	serine/threonine protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	camk/dcamkl protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0035	0.0059	0.0023
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0059	0.0023
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	hypothetical protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	PLK/PLK1 protein kinase	0.0028	0.0036	0.0036
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0059	0.0023
Entamoeba histolytica	serine/threonine-protein kinase 3, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/DYRK/DYRK1 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	STE/STE20/SLK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase 2, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Mycobacterium ulcerans	serine/threonine-protein kinase a PknA	0.0028	0.0036	0.5
Plasmodium falciparum	casein kinase 2, alpha subunit	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	AGC/DMPK/GEK protein kinase	0.0028	0.0036	0.0036
Trypanosoma brucei	protein kinase, putative	0.3051	1	1
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	IRE protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Cam kinase protein 1	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Echinococcus granulosus	lamin dm0	0.0031	0.0048	0.0012
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CAMK/CAMKL/NIM1 protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Mycobacterium leprae	Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B)	0.0028	0.0036	0.5
Brugia malayi	ribosomal protein S6 kinase alpha 3	0.0028	0.0036	0.0036
Brugia malayi	Intermediate filament tail domain containing protein	0.0031	0.0048	0.0048
Loa Loa (eye worm)	STE/STE20/TAO protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/CDK/CRK7 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	serine/threonine protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AGC/PKC/ETA protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	glycogen synthase kinase 3 alpha	0.0028	0.0036	0.0036
Mycobacterium ulcerans	serine/threonine-protein kinase B PknB	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/CDK/CDK8 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	protein kinase C3,putative	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	STE/STE7/MEK7 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	P38 map kinase family protein 2	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	protein kinase C II.	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	AGC/PKC/IOTA protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	p70 ribosomal S6 kinase beta	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Mycobacterium leprae	Probable transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A)	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK-frag	0.0028	0.0036	0.0000000047868
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Ribonuclease 2-5A family protein	0.0028	0.0036	0.0036
Echinococcus granulosus	mitogen activated protein kinase	0.3051	1	1
Loa Loa (eye worm)	CAMK/CAMKL/PASK protein kinase	0.0028	0.0036	0.0036
Chlamydia trachomatis	serine/threonine protein kinase	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	casein kinase 1, delta	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase, FIKK family	0.0028	0.0036	0.5
Brugia malayi	Serine/threonine-protein kinase Nek7	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	HEAT repeat domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	HLS7-interacting protein kinase	0.0028	0.0036	0.0036
Mycobacterium ulcerans	Ser/Thr protein kinase	0.0028	0.0036	0.5
Brugia malayi	activin receptor:ISOTYPE=IIA.	0.0028	0.0036	0.0036
Echinococcus granulosus	intermediate filament protein	0.0031	0.0048	0.0012
Loa Loa (eye worm)	CAMK/CAMKL/MARK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Pre-SET motif family protein	0.0241	0.0739	0.0739
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	CMGC/CLK protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	PEK/HRI protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	receptor protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CAMKK/META protein kinase	0.0028	0.0036	0.0036
Mycobacterium ulcerans	anchored-membrane serine/threonine-protein kinase PknF	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	CASK	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/SRPK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Dual specificity mitogen-activated protein kinase kinase 6	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/TTBK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Plasmodium falciparum	cdc2-related protein kinase 1	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CK1/TTBKL protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/MAPK/P38 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	predicted protein	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1 protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase	0.0028	0.0036	0.5
Plasmodium falciparum	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Phorbol esters/diacylglycerol binding domain	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AUR protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	AGC/DMPK/ROCK protein kinase	0.0028	0.0036	0.0036
Trichomonas vaginalis	TKL family protein kinase	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	protein serine/threonine kinase-1	0.0028	0.0036	0.5
Loa Loa (eye worm)	intermediate filament protein	0.0031	0.0048	0.0048
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Casein kinase II, alpha chain	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Plasmodium falciparum	eukaryotic initiation factor 2alpha kinase 1	0.0028	0.0036	0.5
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Mycobacterium tuberculosis	Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E)	0.0028	0.0036	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	MGC81364 protein	0.0028	0.0036	0.0036
Brugia malayi	serine/threonine kinase 12	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/TTBKL protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	NAK/BIKE protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	TBCK protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0035	0.0059	0.0023
Plasmodium falciparum	serine/threonine protein kinase	0.0028	0.0036	0.5
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Entamoeba histolytica	serine/threonine- protein kinase DCAMKL3, putative	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Plasmodium falciparum	protein kinase 5	0.0028	0.0036	0.5
Loa Loa (eye worm)	CK1/TTBKL protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Trichomonas vaginalis	TKL family protein kinase	0.0028	0.0036	0.0000000047868
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0059	0.0023
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CK1 protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Serine/threonine-protein kinase ZK507.1	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase, putative	0.0028	0.0036	0.5
Plasmodium falciparum	NIMA related kinase 3	0.0028	0.0036	0.5
Echinococcus multilocularis	lamin dm0	0.0031	0.0048	0.0012
Loa Loa (eye worm)	STE/STE20/FRAY protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	camk/mapkapk/mapkapk protein kinase	0.0028	0.0036	0.0036
Plasmodium falciparum	serine/threonine protein kinase	0.0028	0.0036	0.5
Brugia malayi	hypothetical protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	KIAA0303	0.0028	0.0036	0.0036
Plasmodium falciparum	protein kinase, putative	0.0028	0.0036	0.5
Brugia malayi	cell division protein kinase 10	0.0028	0.0036	0.0036
Plasmodium falciparum	calcium-dependent protein kinase 7	0.0028	0.0036	0.5
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.0028	0.0036	0.5
Loa Loa (eye worm)	AUR protein kinase	0.0028	0.0036	0.0036
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Mycobacterium tuberculosis	Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H)	0.0028	0.0036	0.5
Entamoeba histolytica	hypothetical protein	0.0028	0.0036	0.5
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CK1/WORM6 protein kinase	0.0028	0.0036	0.0036
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CAMK protein kinase	0.0028	0.0036	0.0036
Brugia malayi	Serine/threonine-protein kinase Pim-3	0.0028	0.0036	0.0036
Brugia malayi	Hr1 repeat family protein	0.0028	0.0036	0.0036
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	0.3051	1	1
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Plasmodium falciparum	mitogen-activated protein kinase 1	0.0028	0.0036	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0028	0.0036	0.5
Brugia malayi	intermediate filament protein	0.0031	0.0048	0.0048
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Brugia malayi	Protein kinase domain containing protein	0.0028	0.0036	0.0036
Brugia malayi	casein kinase I	0.0028	0.0036	0.0036
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0028	0.0036	0.5
Giardia lamblia	Kinase, NEK	0.0028	0.0036	0.0000000047868
Loa Loa (eye worm)	CAMK/CAMKL/SNRK protein kinase	0.0028	0.0036	0.0036

Activities

Activity type	Activity value	Assay description	Source	Reference
GI50 (functional)	-5.053	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory)	ChEMBL.	No reference
GI50 (functional)	-4	PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory)	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1997245

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1624630