Detailed information for compound 1624777

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 388.222 | Formula: C15H14BrN7O
  • H donors: 3 H acceptors: 4 LogP: 2.38 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cn1ncc(c1)Nc1ncc(c(n1)Nc1ccccc1C(=O)N)Br
  • InChi: 1S/C15H14BrN7O/c1-23-8-9(6-19-23)20-15-18-7-11(16)14(22-15)21-12-5-3-2-4-10(12)13(17)24/h2-8H,1H3,(H2,17,24)(H2,18,20,21,22)
  • InChiKey: KHGPYYFCIAISBU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 4 Starlite/ChEMBL No references
Homo sapiens cyclin-dependent kinase 9 Starlite/ChEMBL No references
Homo sapiens Rho-associated, coiled-coil containing protein kinase 2 Starlite/ChEMBL No references
Homo sapiens glycogen synthase kinase 3 alpha Starlite/ChEMBL No references
Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 3 Starlite/ChEMBL No references
Homo sapiens Janus kinase 2 Starlite/ChEMBL No references
Homo sapiens cyclin-dependent kinase 3 Starlite/ChEMBL No references
Homo sapiens anaplastic lymphoma receptor tyrosine kinase Starlite/ChEMBL No references
Homo sapiens Janus kinase 3 Starlite/ChEMBL No references
Homo sapiens serine/threonine kinase 17a Starlite/ChEMBL No references
Homo sapiens glycogen synthase kinase 3 beta Starlite/ChEMBL No references
Homo sapiens cyclin-dependent kinase 8 Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase kinase kinase kinase 2 Starlite/ChEMBL No references
Homo sapiens protein kinase D3 Starlite/ChEMBL No references
Homo sapiens misshapen-like kinase 1 Starlite/ChEMBL No references
Homo sapiens maternal embryonic leucine zipper kinase Starlite/ChEMBL No references
Homo sapiens protein kinase, cAMP-dependent, catalytic, alpha Starlite/ChEMBL No references
Homo sapiens cell division cycle 7 Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase kinase kinase kinase 4 Starlite/ChEMBL No references
Homo sapiens cyclin-dependent kinase 7 Starlite/ChEMBL No references
Homo sapiens spleen tyrosine kinase Starlite/ChEMBL No references
Homo sapiens death-associated protein kinase 3 Starlite/ChEMBL No references
Homo sapiens protein kinase, X-linked Starlite/ChEMBL No references
Homo sapiens calcium/calmodulin-dependent protein kinase II delta Starlite/ChEMBL No references
Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Starlite/ChEMBL No references
Homo sapiens serine/threonine kinase 3 Starlite/ChEMBL No references
Homo sapiens protein kinase N2 Starlite/ChEMBL No references
Homo sapiens casein kinase 1, alpha 1 Starlite/ChEMBL No references
Homo sapiens CDC-like kinase 2 Starlite/ChEMBL No references
Homo sapiens Pim-1 proto-oncogene, serine/threonine kinase Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase kinase kinase kinase 5 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase Get druggable targets OG5_133787 All targets in OG5_133787
Cryptosporidium hominis protein kinase (EC 2.7.1.37), cAMP-dependent, catalytic chain Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative Get druggable targets OG5_128604 All targets in OG5_128604
Trypanosoma congolense cAMP-dependent protein kinase catalytic subunit 1 Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma brucei gambiense protein kinase A catalytic subunit isoform 1,protein kinase A catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Neospora caninum AGC kinase, putative Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_135071 All targets in OG5_135071
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_130229 All targets in OG5_130229
Leishmania mexicana protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Onchocerca volvulus Serine\/threonine protein kinase homolog Get druggable targets OG5_134863 All targets in OG5_134863
Trypanosoma brucei CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_132231 All targets in OG5_132231
Schistosoma japonicum ko:K06070 protein kinase D, putative Get druggable targets OG5_130080 All targets in OG5_130080
Leishmania mexicana protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma mansoni kinase Get druggable targets OG5_130531 All targets in OG5_130531
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129189 All targets in OG5_129189
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 Get druggable targets OG5_128147 All targets in OG5_128147
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132231 All targets in OG5_132231
Leishmania donovani serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi intracellular kinase Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CDC7 Get druggable targets OG5_129189 All targets in OG5_129189
Schistosoma japonicum ko:K02211 cyclin-dependent kinase 9, putative Get druggable targets OG5_130531 All targets in OG5_130531
Schistosoma japonicum Serine/threonine-protein kinase mig-15, putative Get druggable targets OG5_128641 All targets in OG5_128641
Theileria parva cAMP-dependent protein kinase catalytic subunit, putative Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma mansoni protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis calcium dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis STE family protein kinase Get druggable targets OG5_128604 All targets in OG5_128604
Echinococcus multilocularis protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126990 All targets in OG5_126990
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129224 All targets in OG5_129224
Plasmodium berghei calcium-dependent protein kinase 4 Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus serine:threonine protein kinase mig 15 Get druggable targets OG5_128641 All targets in OG5_128641
Echinococcus granulosus glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania braziliensis rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Leishmania infantum protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus multilocularis tyrosine protein kinase shark Get druggable targets OG5_131855 All targets in OG5_131855
Schistosoma japonicum ko:K08282 non-specific serine/threonine protein kinase [EC2.7.11.1], putative Get druggable targets OG5_128641 All targets in OG5_128641
Onchocerca volvulus Get druggable targets OG5_130080 All targets in OG5_130080
Onchocerca volvulus Get druggable targets OG5_130080 All targets in OG5_130080
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania braziliensis protein kinase A catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum expressed protein Get druggable targets OG5_130080 All targets in OG5_130080
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Serine/threonine-protein kinase Doa, putative Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus multilocularis maternal embryonic leucine zipper kinase Get druggable targets OG5_133787 All targets in OG5_133787
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium yoelii calcium-dependent protein kinase-3 Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni serine/threonine kinase Get druggable targets OG5_133787 All targets in OG5_133787
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_131855 All targets in OG5_131855
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Giardia lamblia Kinase, CK1 Casein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis rho associated protein kinase Get druggable targets OG5_131020 All targets in OG5_131020
Echinococcus granulosus calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative Get druggable targets OG5_126748 All targets in OG5_126748
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Loa Loa (eye worm) CMGC/CLK protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Plasmodium knowlesi calcium-dependent protein kinase 3, putative Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium falciparum calcium-dependent protein kinase 3 Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium parvum calmodulin-domain protein kinase 1, putative Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus enhancer of mRNA decapping protein 4 Get druggable targets OG5_126748 All targets in OG5_126748
Leishmania major casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Candida albicans kinase required for spore wall formation Get druggable targets OG5_128604 All targets in OG5_128604
Echinococcus multilocularis serine:threonine protein kinase PAK 4 Get druggable targets OG5_131977 All targets in OG5_131977
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_134863 All targets in OG5_134863
Trypanosoma brucei gambiense protein kinase A catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Candida albicans cAMP-dependent protein kinase Get druggable targets OG5_126748 All targets in OG5_126748
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum IPR002219,Protein kinase C, phorbol ester/diacylglycerol binding,domain-containing Get druggable targets OG5_131020 All targets in OG5_131020
Brugia malayi Phorbol esters/diacylglycerol binding domain Get druggable targets OG5_130080 All targets in OG5_130080
Trypanosoma congolense kinetoplastid kinetochore protein, putative Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum IPR000719,Protein kinase;IPR011009,Protein kinase-like,domain-containing Get druggable targets OG5_128147 All targets in OG5_128147
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_133787 All targets in OG5_133787
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126748 All targets in OG5_126748
Leishmania mexicana protein kinase A catalytic subunit isoform 1 Get druggable targets OG5_126748 All targets in OG5_126748
Plasmodium falciparum calcium-dependent protein kinase 2 Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus rho-associated protein kinase 1 Get druggable targets OG5_131020 All targets in OG5_131020
Trypanosoma brucei kinetoplastid kinetochore protein 10 Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum Calcium/calmodulin-dependent protein kinase type II alpha chain, putative Get druggable targets OG5_126600 All targets in OG5_126600
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Serine/threonine-protein kinase N1, putative Get druggable targets OG5_130229 All targets in OG5_130229
Echinococcus multilocularis myosin iiia Get druggable targets OG5_128604 All targets in OG5_128604
Candida albicans Serine/threonine protein kinase Get druggable targets OG5_128147 All targets in OG5_128147
Leishmania mexicana protein kinase A catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Theileria parva calmodulin-domain protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126748 All targets in OG5_126748
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_130531 All targets in OG5_130531
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum cAMP-dependent protein kinase catalytic subunit alpha, putative Get druggable targets OG5_126748 All targets in OG5_126748
Trichomonas vaginalis CK1 family protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Entamoeba histolytica serine/threonine-protein kinase 3, putative Get druggable targets OG5_128604 All targets in OG5_128604
Trypanosoma congolense casein kinase I, isoform 2 Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K08799 maternal embryonic leucine zipper kinase, putative Get druggable targets OG5_133787 All targets in OG5_133787
Entamoeba histolytica casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Entamoeba histolytica serine/threonine protein kinase STE20, putative Get druggable targets OG5_128604 All targets in OG5_128604
Leishmania major protein kinase A catalytic subunit isoform 2 Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum ko:K08959 casein kinase 1, delta, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis enhancer of mRNA decapping protein 4 Get druggable targets OG5_126748 All targets in OG5_126748
Plasmodium falciparum calcium-dependent protein kinase 1 Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum Calcium/calmodulin-dependent protein kinase type 1, putative Get druggable targets OG5_126600 All targets in OG5_126600
Brugia malayi casein kinase I Get druggable targets OG5_126780 All targets in OG5_126780
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain Get druggable targets OG5_126748 All targets in OG5_126748
Candida albicans CDC2-related protein kinase Get druggable targets OG5_130531 All targets in OG5_130531
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CK1 family protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii AGC kinase Get druggable targets OG5_126748 All targets in OG5_126748
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_129229 All targets in OG5_129229
Schistosoma japonicum Casein kinase I isoform delta, putative Get druggable targets OG5_126780 All targets in OG5_126780
Candida albicans Serine-threonine kinase, subunit of RNA Pol TFIIK. Get druggable targets OG5_129224 All targets in OG5_129224
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum IPR000719,Protein kinase,domain-containing Get druggable targets OG5_128147 All targets in OG5_128147
Leishmania mexicana serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium knowlesi calcium-dependent protein kinase 5, putative Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium vivax glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans Serine-threonine protein kinase similar to S. cerevisiae CMK2 (YOL016C) calcium/calmodulin-dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Loa Loa (eye worm) CAMK/PIM protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Plasmodium vivax calcium-dependent protein kinase 4, putative Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma brucei gambiense protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 19 Get druggable targets OG5_129229 All targets in OG5_129229
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus multilocularis cyclin dependent kinase 9 Get druggable targets OG5_130531 All targets in OG5_130531
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Plasmodium vivax serine/threonine kinase-1, putative Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum expressed protein Get druggable targets OG5_130229 All targets in OG5_130229
Leishmania major protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Onchocerca volvulus Get druggable targets OG5_130080 All targets in OG5_130080
Plasmodium falciparum calcium-dependent protein kinase 4 Get druggable targets OG5_126600 All targets in OG5_126600
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major protein kinase A catalytic subunit isoform 1 Get druggable targets OG5_126748 All targets in OG5_126748
Onchocerca volvulus Get druggable targets OG5_129189 All targets in OG5_129189
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus granulosus casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum expressed protein Get druggable targets OG5_129224 All targets in OG5_129224
Candida albicans Casein kinase I: DNA repair, meiosis Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania major protein kinase A catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma congolense protein kinase A catalytic subunit 3 Get druggable targets OG5_126748 All targets in OG5_126748
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis Get druggable targets OG5_126990 All targets in OG5_126990
Onchocerca volvulus Get druggable targets OG5_129189 All targets in OG5_129189
Brugia malayi probable protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Giardia lamblia Kinase, AGC PKA Get druggable targets OG5_126748 All targets in OG5_126748
Giardia lamblia Kinase, CMGC CLK Get druggable targets OG5_126990 All targets in OG5_126990
Loa Loa (eye worm) CAMK/PKD protein kinase Get druggable targets OG5_130080 All targets in OG5_130080
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126748 All targets in OG5_126748
Theileria parva casein kinase I, putative Get druggable targets OG5_126780 All targets in OG5_126780
Plasmodium knowlesi calcium-dependent protein kinase 1, putative Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania infantum protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative Get druggable targets OG5_126990 All targets in OG5_126990
Candida albicans Serine/threonine protein kinase required for induction of IME2 by Ime1p Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium vivax calcium-dependent protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus multilocularis serine:threonine protein kinase N2 Get druggable targets OG5_130229 All targets in OG5_130229
Plasmodium vivax calcium-dependent protein kinase 3, putative Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus granulosus cyclin dependent kinase 19 Get druggable targets OG5_129229 All targets in OG5_129229
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_129189 All targets in OG5_129189
Schistosoma mansoni protein kinase Get druggable targets OG5_129692 All targets in OG5_129692
Loa Loa (eye worm) TK/ALK protein kinase Get druggable targets OG5_132231 All targets in OG5_132231
Plasmodium yoelii protein serine/threonine kinase-1 Get druggable targets OG5_126990 All targets in OG5_126990
Candida albicans cAMP-dependent protein kinase Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CAMK/PKD protein kinase Get druggable targets OG5_130080 All targets in OG5_130080
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus multilocularis dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis CK1 family protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Candida albicans Serine/threonine protein kinase Get druggable targets OG5_128147 All targets in OG5_128147
Schistosoma japonicum Mitogen-activated protein kinase kinase kinase kinase 3, putative Get druggable targets OG5_129692 All targets in OG5_129692
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania braziliensis protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans protein kinase A Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus multilocularis Get druggable targets OG5_128641 All targets in OG5_128641
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum Ribosomal protein S6 kinase alpha-2, putative Get druggable targets OG5_128147 All targets in OG5_128147
Onchocerca volvulus Get druggable targets OG5_126888 All targets in OG5_126888
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus multilocularis casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis proto oncogene serine:threonine protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Plasmodium berghei casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma congolense kinetoplastid kinetochore protein, putative Get druggable targets OG5_126990 All targets in OG5_126990
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium knowlesi cAMP-dependent protein kinase catalytic subunit, putative Get druggable targets OG5_126748 All targets in OG5_126748
Candida albicans protein serine/threonine kinase Get druggable targets OG5_129189 All targets in OG5_129189
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Loa Loa (eye worm) STE/STE20/MSN protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Leishmania major protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania mexicana protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Candida albicans kinase required for spore wall formation Get druggable targets OG5_128604 All targets in OG5_128604
Leishmania infantum protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Plasmodium yoelii casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus serine:threonine protein kinase PAK 4 Get druggable targets OG5_131977 All targets in OG5_131977
Cryptosporidium parvum calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands Get druggable targets OG5_126600 All targets in OG5_126600
Candida albicans hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Trypanosoma brucei gambiense protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Toxoplasma gondii AGC kinase Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum ko:K04702 proto-oncogene serine/threonine-protein kinase Pim-1, putative Get druggable targets OG5_134863 All targets in OG5_134863
Plasmodium vivax casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum IPR000437,Prokaryotic membrane lipoprotein lipid attachment site,domain-containing Get druggable targets OG5_128641 All targets in OG5_128641
Plasmodium berghei cAMP-dependent protein kinase catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus granulosus casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum ko:K08822 glycogen synthase kinase 3 alpha, putative Get druggable targets OG5_126888 All targets in OG5_126888
Neospora caninum Calmodulin-like domain protein kinase isoenzyme gamma, related Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania major protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 Get druggable targets OG5_126748 All targets in OG5_126748
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus multilocularis CDC7 cell division cycle 7 Get druggable targets OG5_129189 All targets in OG5_129189
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_129189 All targets in OG5_129189
Schistosoma japonicum Rho-associated protein kinase 1, putative Get druggable targets OG5_131020 All targets in OG5_131020
Candida albicans Cyclin-dependent serine/threonin protein kinase Get druggable targets OG5_129229 All targets in OG5_129229
Leishmania infantum protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_126748 All targets in OG5_126748
Theileria parva cAMP-dependent protein kinase, putative Get druggable targets OG5_126748 All targets in OG5_126748
Neospora caninum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium berghei calcium-dependent protein kinase 3 Get druggable targets OG5_126600 All targets in OG5_126600
Theileria parva glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans Cyclin-dependent serine/threonin protein kinase Get druggable targets OG5_129229 All targets in OG5_129229
Brugia malayi Hr1 repeat family protein Get druggable targets OG5_130229 All targets in OG5_130229
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum cAMP-dependent protein kinase catalytic subunit alpha, putative Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus granulosus casein kinase I alpha Get druggable targets OG5_126780 All targets in OG5_126780
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase Get druggable targets OG5_131020 All targets in OG5_131020
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) AGC/PKN protein kinase Get druggable targets OG5_130229 All targets in OG5_130229
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi cyclin-dependent kinase 7 homolog Get druggable targets OG5_129224 All targets in OG5_129224
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium falciparum casein kinase 1 Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum Mitogen-activated protein kinase kinase kinase kinase 4, putative Get druggable targets OG5_128641 All targets in OG5_128641
Schistosoma japonicum ko:K02218 casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Cryptosporidium hominis serine/threonine kinase-1 Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Echinococcus granulosus maternal embryonic leucine zipper kinase Get druggable targets OG5_133787 All targets in OG5_133787
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_131020 All targets in OG5_131020
Theileria parva serine/threonine protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus calcium dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative Get druggable targets OG5_126990 All targets in OG5_126990
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126748 All targets in OG5_126748
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_129692 All targets in OG5_129692
Schistosoma japonicum ko:K08823 CDC-like kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Loa Loa (eye worm) STE/STE20/MST protein kinase Get druggable targets OG5_128604 All targets in OG5_128604
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania infantum protein kinase A catalytic subunit isoform 2 Get druggable targets OG5_126748 All targets in OG5_126748
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Onchocerca volvulus Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania mexicana rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Schistosoma japonicum ko:K08794 calcium/calmodulin-dependent protein kinase I, putative Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania mexicana Get druggable targets OG5_126990 All targets in OG5_126990
Plasmodium berghei glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania braziliensis protein kinase A catalytic subunit isoform 1 Get druggable targets OG5_126748 All targets in OG5_126748
Babesia bovis calcium-dependent protein kinase 4 Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus proto oncogene serine:threonine protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 Get druggable targets OG5_128147 All targets in OG5_128147
Loa Loa (eye worm) STE/STE20/PAKB protein kinase Get druggable targets OG5_131977 All targets in OG5_131977
Onchocerca volvulus Get druggable targets OG5_131020 All targets in OG5_131020
Giardia lamblia Kinase, STE STE20 Get druggable targets OG5_128604 All targets in OG5_128604
Plasmodium falciparum calcium-dependent protein kinase 5 Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Loa Loa (eye worm) CAMK/CAMK2 protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) Get druggable targets OG5_126888 All targets in OG5_126888
Toxoplasma gondii calcium-dependent protein kinase CDPK3 Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus dual specificity protein kinase clk2 Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_128147 All targets in OG5_128147
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus granulosus mitogen activated protein kinase kinase kinase Get druggable targets OG5_129692 All targets in OG5_129692
Candida albicans Serine-threonine kinase, subunit of RNA Pol TFIIK. Get druggable targets OG5_129224 All targets in OG5_129224
Babesia bovis protein serine/threonine kinase 1 Get druggable targets OG5_126990 All targets in OG5_126990
Cryptosporidium parvum calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands Get druggable targets OG5_126600 All targets in OG5_126600
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, AGC AKT Get druggable targets OG5_128147 All targets in OG5_128147
Brugia malayi ribosomal protein S6 kinase alpha 3 Get druggable targets OG5_128147 All targets in OG5_128147
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_131855 All targets in OG5_131855
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_133787 All targets in OG5_133787
Echinococcus multilocularis glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium parvum serine/threonine kinase-1 Get druggable targets OG5_126990 All targets in OG5_126990
Toxoplasma gondii calcium-dependent protein kinase CDPK2A Get druggable targets OG5_126600 All targets in OG5_126600
Brugia malayi C1-like domain containing protein Get druggable targets OG5_130080 All targets in OG5_130080
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_129189 All targets in OG5_129189
Echinococcus multilocularis cyclin dependent kinase 9 Get druggable targets OG5_130531 All targets in OG5_130531
Plasmodium berghei calcium-dependent protein kinase 1 Get druggable targets OG5_126600 All targets in OG5_126600
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_133787 All targets in OG5_133787
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126748 All targets in OG5_126748
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126600 All targets in OG5_126600
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_129189 All targets in OG5_129189
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 7 Get druggable targets OG5_129224 All targets in OG5_129224
Schistosoma japonicum Protein kinase DC2, putative Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum Serine/threonine-protein kinase N2, putative Get druggable targets OG5_130229 All targets in OG5_130229
Loa Loa (eye worm) STE/STE20/KHS protein kinase Get druggable targets OG5_129692 All targets in OG5_129692
Entamoeba histolytica casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) AGC/PKA protein kinase Get druggable targets OG5_126748 All targets in OG5_126748
Candida albicans similar ot C terminus of S. cerevisiae SGV1 (YPR161C) Get druggable targets OG5_130531 All targets in OG5_130531
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Echinococcus multilocularis dual specificity protein kinase clk2 Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania infantum protein kinase A catalytic subunit isoform 1 Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129229 All targets in OG5_129229
Loa Loa (eye worm) CAMK/PIM protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Trypanosoma brucei gambiense protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Onchocerca volvulus Get druggable targets OG5_131020 All targets in OG5_131020
Schistosoma japonicum Serine/threonine-protein kinase minibrain, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus multilocularis mitogen activated protein kinase kinase kinase Get druggable targets OG5_129692 All targets in OG5_129692
Plasmodium berghei calcium-dependent protein kinase 5 Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania major protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Neospora caninum hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus cyclin dependent kinase 9 Get druggable targets OG5_130531 All targets in OG5_130531
Leishmania infantum rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Schistosoma japonicum Serine/threonine-protein kinase 17B, putative Get druggable targets OG5_135071 All targets in OG5_135071
Schistosoma japonicum IPR001180,Citron-like,domain-containing Get druggable targets OG5_129692 All targets in OG5_129692
Candida albicans Serine-threonine protein kinase similar to S. cerevisiae CMK2 (YOL016C) calcium/calmodulin-dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum Serine/threonine-protein kinase mig-15, putative Get druggable targets OG5_128641 All targets in OG5_128641
Cryptosporidium hominis casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus cyclin dependent kinase 9 Get druggable targets OG5_130531 All targets in OG5_130531
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Loa Loa (eye worm) CDC7 protein kinase Get druggable targets OG5_129189 All targets in OG5_129189
Echinococcus granulosus serine:threonine protein kinase N2 Get druggable targets OG5_130229 All targets in OG5_130229
Leishmania braziliensis protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus granulosus tyrosine protein kinase shark Get druggable targets OG5_131855 All targets in OG5_131855
Echinococcus multilocularis serine:threonine protein kinase 3 Get druggable targets OG5_128604 All targets in OG5_128604
Trypanosoma brucei protein kinase A catalytic subunit, putative Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum cAMP-dependent protein kinase catalytic subunit, putative Get druggable targets OG5_126748 All targets in OG5_126748
Leishmania infantum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 Get druggable targets OG5_126748 All targets in OG5_126748
Plasmodium berghei serine/threonine kinase-1, putative Get druggable targets OG5_126990 All targets in OG5_126990
Cryptosporidium hominis calcium-dependent protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase Get druggable targets OG5_130531 All targets in OG5_130531
Cryptosporidium parvum protein kinase, cAMP-dependent, catalytic chain Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum ko:K06070 protein kinase D, putative Get druggable targets OG5_130080 All targets in OG5_130080
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum ko:K02211 cyclin-dependent kinase 9, putative Get druggable targets OG5_130531 All targets in OG5_130531
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Loa Loa (eye worm) gastrulation defective protein 1 Get druggable targets OG5_129229 All targets in OG5_129229
Leishmania donovani casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus multilocularis casein kinase I delta Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Brugia malayi Serine/threonine-protein kinase Pim-3 Get druggable targets OG5_134863 All targets in OG5_134863
Schistosoma japonicum ko:K04515 calcium/calmodulin-dependent protein kinase (CaM kinase) II, putative Get druggable targets OG5_126600 All targets in OG5_126600
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis serine:threonine protein kinase N2 Get druggable targets OG5_130229 All targets in OG5_130229
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Candida albicans Serine/threonine protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus multilocularis casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania donovani glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni protein kinase Get druggable targets OG5_128641 All targets in OG5_128641
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126748 All targets in OG5_126748
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Cryptosporidium parvum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani rac serine-threonine kinase, putative Get druggable targets OG5_128147 All targets in OG5_128147
Schistosoma japonicum expressed protein Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus granulosus casein kinase i Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania donovani protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni protein kinase C mu Get druggable targets OG5_130080 All targets in OG5_130080
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130080 All targets in OG5_130080
Echinococcus granulosus serine:threonine protein kinase 3 Get druggable targets OG5_128604 All targets in OG5_128604
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania infantum serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi STE20-like kinase MST Get druggable targets OG5_128604 All targets in OG5_128604
Plasmodium knowlesi casein kinase 1, putative Get druggable targets OG5_126780 All targets in OG5_126780
Candida albicans protein kinase A Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 Get druggable targets OG5_126748 All targets in OG5_126748
Leishmania donovani protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_130531 All targets in OG5_130531
Schistosoma japonicum ko:K08286 protein-serine/threonine kinase [EC2.7.11.-], putative Get druggable targets OG5_129692 All targets in OG5_129692
Leishmania mexicana protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 7 Get druggable targets OG5_129224 All targets in OG5_129224
Leishmania braziliensis protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Trypanosoma brucei gambiense protein kinase A catalytic subunit isoform 2,protein kinase A catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Theileria parva calcium-dependent protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Neospora caninum AGC kinase, putative Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma brucei casein kinase I, isoform 2 Get druggable targets OG5_126780 All targets in OG5_126780
Cryptosporidium hominis calmodulin-domain protein kinase 1 Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma brucei gambiense casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus CDC7 cell division cycle 7 Get druggable targets OG5_129189 All targets in OG5_129189
Plasmodium falciparum protein serine/threonine kinase-1 Get druggable targets OG5_126990 All targets in OG5_126990
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium knowlesi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium yoelii calcium-dept. protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_133787 All targets in OG5_133787
Neospora caninum AFL091Wp, related Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii calcium-dependent protein kinase CDPK2B Get druggable targets OG5_126600 All targets in OG5_126600
Onchocerca volvulus Get druggable targets OG5_126780 All targets in OG5_126780
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Candida albicans Casein kinase I: DNA repair, meiosis Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania infantum protein kinase A catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma congolense casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative Get druggable targets OG5_126990 All targets in OG5_126990
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative Get druggable targets OG5_126748 All targets in OG5_126748
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase Get druggable targets OG5_129224 All targets in OG5_129224
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) AGC/RSK/RSK protein kinase Get druggable targets OG5_128147 All targets in OG5_128147
Leishmania mexicana casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Echinococcus granulosus calcium:calmodulin dependent protein kinase type Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum expressed protein Get druggable targets OG5_126990 All targets in OG5_126990
Neospora caninum hypothetical protein Get druggable targets OG5_126990 All targets in OG5_126990
Plasmodium knowlesi serine/threonine kinase-1, putative Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Leishmania mexicana protein kinase A catalytic subunit isoform 2 Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus granulosus protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum ko:K05855 spleen tyrosine kinase, putative Get druggable targets OG5_131855 All targets in OG5_131855
Trypanosoma brucei kinetoplastid kinetochore protein 19 Get druggable targets OG5_126990 All targets in OG5_126990
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126990 All targets in OG5_126990
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Candida albicans Serine/threonine protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum hypothetical protein Get druggable targets OG5_129692 All targets in OG5_129692
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium knowlesi calcium-dependent protein kinase 4, putative Get druggable targets OG5_126600 All targets in OG5_126600
Leishmania braziliensis casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi cyclin-dependent kinase 9 Get druggable targets OG5_130531 All targets in OG5_130531
Brugia malayi serine/threonine-protein kinase PAK 7 Get druggable targets OG5_131977 All targets in OG5_131977
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128641 All targets in OG5_128641
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_131020 All targets in OG5_131020
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania braziliensis serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma cruzi casein kinase, delta isoform, putative Get druggable targets OG5_126780 All targets in OG5_126780
Brugia malayi casein kinase 1, delta Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum gsx family homeobox protein; serine/threonine kinase Get druggable targets OG5_133787 All targets in OG5_133787
Schistosoma japonicum ko:K02208 cyclin-dependent kinase 8/11, putative Get druggable targets OG5_129229 All targets in OG5_129229
Cryptosporidium hominis CDPK2 Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium yoelii calmodulin-domain protein kinase Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Candida albicans protein serine/threonine kinase Get druggable targets OG5_129189 All targets in OG5_129189
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative Get druggable targets OG5_126600 All targets in OG5_126600
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase Get druggable targets OG5_129229 All targets in OG5_129229
Cryptosporidium parvum calcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma brucei gambiense protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus multilocularis death associated protein kinase 1 Get druggable targets OG5_144770 All targets in OG5_144770
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit Get druggable targets OG5_126748 All targets in OG5_126748
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum ko:K04345 protein kinase A, putative Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus granulosus serine:threonine protein kinase N2 Get druggable targets OG5_130229 All targets in OG5_130229
Leishmania infantum casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
Leishmania donovani protein kinase A catalytic subunit 3 Get druggable targets OG5_126748 All targets in OG5_126748
Echinococcus granulosus dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium knowlesi protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Cryptosporidium parvum casein kinase I Get druggable targets OG5_126780 All targets in OG5_126780
Plasmodium yoelii Plasmodium falciparum CDPK2 protein Get druggable targets OG5_126600 All targets in OG5_126600
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma japonicum IPR000719,Protein kinase;IPR011009,Protein kinase-like,domain-containing Get druggable targets OG5_126748 All targets in OG5_126748
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 Get druggable targets OG5_126600 All targets in OG5_126600
Toxoplasma gondii casein kinase I Get druggable targets OG5_126780 All targets in OG5_126780
Babesia bovis casein kinase I, putative Get druggable targets OG5_126780 All targets in OG5_126780
Schistosoma japonicum Calcium/calmodulin-dependent protein kinase type II delta chain, putative Get druggable targets OG5_126600 All targets in OG5_126600
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129224 All targets in OG5_129224
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_128604 All targets in OG5_128604
Schistosoma japonicum Calcium/calmodulin-dependent protein kinase type II beta chain, putative Get druggable targets OG5_126600 All targets in OG5_126600
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_129692 All targets in OG5_129692
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Loa Loa (eye worm) AGC/PKA protein kinase Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum IPR000961,Protein kinase, C-terminal,domain-containing Get druggable targets OG5_130229 All targets in OG5_130229
Cryptosporidium hominis serine/threonine protein kinase; possibly sporulation specific Get druggable targets OG5_128604 All targets in OG5_128604
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense kinetoplastid kinetochore protein 10, putative Get druggable targets OG5_126990 All targets in OG5_126990
Brugia malayi Cam kinase protein 1 Get druggable targets OG5_126600 All targets in OG5_126600
Echinococcus granulosus hypothetical protein Get druggable targets OG5_126990 All targets in OG5_126990
Neospora caninum Calcium-dependent protein kinase 2, related Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma congolense cAMP-dependent protein kinase catalytic subunit 1 Get druggable targets OG5_126748 All targets in OG5_126748
Schistosoma japonicum ko:K08253 non-specific protein-tyrosine kinase [EC2.7.10.2], putative Get druggable targets OG5_131855 All targets in OG5_131855
Schistosoma japonicum ko:K02214 cell division control protein CDC7, putative Get druggable targets OG5_129189 All targets in OG5_129189
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K04345 protein kinase A, putative Get druggable targets OG5_126748 All targets in OG5_126748
Trypanosoma cruzi casein kinase, delta isoform, putative Get druggable targets OG5_126780 All targets in OG5_126780
Trypanosoma brucei gambiense serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium vivax calcium-dependent protein kinase 1, putative Get druggable targets OG5_126600 All targets in OG5_126600
Trypanosoma cruzi casein kinase, putative Get druggable targets OG5_126780 All targets in OG5_126780
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 3 305 aa 303 aa 32.0 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 9 372 aa 313 aa 31.6 %
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 7 346 aa 311 aa 32.5 %
Brugia malayi Protein kinase domain containing protein casein kinase 1, alpha 1 365 aa 307 aa 24.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0087 0.0055 0.194
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0088 0.006 0.0053
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0087 0.0055 0.0348
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.1393 0.5143 0.6547
Plasmodium falciparum glycogen synthase kinase 3 0.0127 0.0214 0.1605
Leishmania major zinc-binding dehydrogenase-like protein 0.0087 0.0055 0.0348
Onchocerca volvulus 0.0085 0.0049 0.0048
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0214 0.1532
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0095 0.0088 0.01
Schistosoma mansoni protein kinase 0.0164 0.0356 0.179
Leishmania major protein kinase, putative 0.0085 0.0048 0.0301
Loa Loa (eye worm) hypothetical protein 0.0121 0.019 0.0215
Entamoeba histolytica protein kinase, putative 0.012 0.0184 0.6869
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0109 0.0141 0.1238
Mycobacterium leprae conserved hypothetical protein 0.0141 0.0266 0.0271
Echinococcus granulosus tyrosine protein kinase shark 0.0276 0.0792 0.6201
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0141 0.0601
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0214 0.055 0.0637
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.1393 0.5143 0.6547
Loa Loa (eye worm) AGC/PKN protein kinase 0.0198 0.0487 0.0552
Onchocerca volvulus 0.0083 0.004 0.0037
Mycobacterium ulcerans polyketide synthase 0.1479 0.548 0.6981
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0141 0.0266 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0126 0.0521
Mycobacterium tuberculosis Hypothetical protein 0.042 0.1352 0.1669
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.1161 0.4238 0.5384
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0109 0.0141 0.0895
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0109 0.0141 0.1238
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0085 0.0048 0.0377
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0086 0.0053 0.0059
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0087 0.0055 0.0153
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0087 0.0055 0.0436
Echinococcus multilocularis cyclin dependent kinase 9 0.0076 0.0014 0.004
Echinococcus multilocularis CDC7 cell division cycle 7 0.0081 0.0032 0.0089
Onchocerca volvulus 0.2424 0.916 0.9645
Schistosoma mansoni serine/threonine protein kinase 0.0546 0.1843 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0141 0.0266 0.0235
Toxoplasma gondii acyl carrier protein ACP 0.0141 0.0266 0.04
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.035 0.1079 1
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0449 0.2306
Mycobacterium ulcerans acyl-CoA synthetase 0.0141 0.0266 0.0271
Entamoeba histolytica acyl-CoA synthetase, putative 0.0141 0.0266 1
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0087 0.0055 0.0023
Giardia lamblia Methyltransferase like 2 0.042 0.1352 1
Mycobacterium ulcerans polyketide synthase Pks9 0.0921 0.3305 0.4183
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0085 0.0048 0.0377
Onchocerca volvulus 0.0087 0.0055 0.0053
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.1479 0.548 0.6981
Giardia lamblia Kinase, CMGC GSK 0.0127 0.0214 0.1532
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.035 0.1079 1
Schistosoma mansoni [ACP] S-malonyltransferase 0.0088 0.006 0.0156
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0109 0.0141 0.0393
Schistosoma mansoni protein kinase 0.0278 0.08 0.4243
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0087 0.0055 0.0348
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0141 0.0266 0.0271
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0214 0.055 0.0637
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0281 0.0813 0.0921
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0141 0.0266 0.0271
Loa Loa (eye worm) hypothetical protein 0.0107 0.0135 0.0153
Brugia malayi Hr1 repeat family protein 0.0198 0.0487 0.0457
Giardia lamblia Kinase, CDC7 0.0081 0.0032 0.0178
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0121 0.019 0.1697
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0233 0.0624 0.0707
Trypanosoma brucei oxidoreductase, putative 0.0087 0.0055 0.0436
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.035 0.1079 0.5784
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.012 0.0184 0.1641
Loa Loa (eye worm) CDC7 protein kinase 0.0081 0.0032 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.015 0.1059
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.035 0.1079 1
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0204 0.0514 0.1435
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0032 0.0178
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0274 0.1339
Echinococcus granulosus CDC7 cell division cycle 7 0.0081 0.0032 0.025
Brugia malayi Protein kinase domain containing protein 0.0558 0.1892 0.1866
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0704 0.2459 0.4439
Leishmania major d-xylulose reductase, putative 0.0087 0.0055 0.0348
Leishmania major oxidoreductase-like protein 0.0087 0.0055 0.0348
Brugia malayi Methyltransferase-like protein 4 0.042 0.1352 0.1324
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0133 0.0237 0.0206
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.1001 0.3615 0.4581
Brugia malayi Protein kinase domain containing protein 0.04 0.1277 0.1249
Echinococcus granulosus serine:threonine protein kinase 3 0.0281 0.0813 0.6369
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0087 0.0055 0.0429
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0214 0.1532
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0127 0.0214 0.0242
Echinococcus granulosus dual specificity 0.012 0.0184 0.1439
Entamoeba histolytica protein kinase, putative 0.012 0.0184 0.6869
Brugia malayi Protein kinase domain containing protein 0.0085 0.0048 0.0017
Toxoplasma gondii type I fatty acid synthase, putative 0.0992 0.3579 0.6501
Toxoplasma gondii type I fatty acid synthase, putative 0.1479 0.548 1
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0096 0.0092 0.0258
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0164 0.0356 0.0995
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0164 0.0356 0.2788
Trypanosoma brucei acyl transferase-like protein 0.0088 0.006 0.0487
Mycobacterium tuberculosis Polyketide synthase Pks12 0.1479 0.548 0.6981
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.035 0.1079 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0109 0.0141 0.0393
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0141 0.0266 0.0271
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0109 0.0141 0.0109
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0032 0.0178
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0109 0.0141 0.1238
Plasmodium falciparum acyl carrier protein 0.0141 0.0266 0.2108
Giardia lamblia Kinase, AGC AKT 0.0113 0.016 0.1128
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0141 0.0266 0.0271
Echinococcus multilocularis rho associated protein kinase 0.0188 0.0449 0.1256
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0141 0.0266 0.0271
Echinococcus multilocularis AMP dependent ligase 0.0141 0.0266 0.0742
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.1121 0.4083 0.5183
Mycobacterium leprae Probable polyketide synthase Pks1 0.1479 0.548 0.6981
Echinococcus granulosus protein kinase 0.0157 0.0328 0.2571
Mycobacterium tuberculosis Polyketide synthase Pks13 0.2082 0.7826 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.1393 0.5143 0.6547
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0141 0.0266 0.0271
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0087 0.0055 0.194
Loa Loa (eye worm) hypothetical protein 0.0088 0.006 0.0068
Toxoplasma gondii AGC kinase 0.0109 0.0141 0.017
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0479 0.1583 0.1966
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0121 0.019 0.1697
Schistosoma mansoni serine/threonine kinase 0.017 0.0378 0.1911
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0514 0.266
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.1121 0.4083 0.5183
Leishmania major protein kinase, putative 0.0085 0.0048 0.0301
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.012 0.0184 0.1641
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0143 0.0274 0.0765
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.1479 0.548 0.6981
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0116 0.0169 0.12
Onchocerca volvulus 0.0081 0.0032 0.0029
Onchocerca volvulus 0.0087 0.0055 0.0053
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0558 0.1892 0.2142
Brugia malayi probable protein kinase 0.0278 0.08 0.0771
Schistosoma mansoni methyltransferase-related 0.042 0.1352 0.729
Plasmodium vivax glycogen synthase kinase 3, putative 0.0127 0.0214 0.1605
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0109 0.0141 0.1102
Trichomonas vaginalis CAMK family protein kinase 0.016 0.0341 0.2477
Echinococcus multilocularis myosin iiia 0.0075 0.0008 0.0022
Mycobacterium tuberculosis Conserved hypothetical protein 0.0141 0.0266 0.0271
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.1393 0.5143 0.6547
Leishmania major nuclear receptor binding factor-like protein 0.0087 0.0055 0.0348
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0126 0.0521
Echinococcus multilocularis tyrosine protein kinase shark 0.0276 0.0792 0.2212
Entamoeba histolytica protein kinase, putative 0.0127 0.0214 0.8018
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0109 0.0141 0.1102
Brugia malayi Protein kinase domain containing protein 0.017 0.0379 0.0349
Leishmania major hypothetical protein, conserved 0.0088 0.006 0.0388
Loa Loa (eye worm) acyl carrier protein 0.0641 0.2212 0.2505
Mycobacterium ulcerans acyl carrier protein 0.0141 0.0266 0.0271
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.035 0.1079 0.7972
Loa Loa (eye worm) hypothetical protein 0.0085 0.0049 0.0056
Leishmania major quinone oxidoreductase, putative 0.0087 0.0055 0.0348
Loa Loa (eye worm) hypothetical protein 0.0121 0.019 0.0215
Brugia malayi Temporarily assigned gene name protein 59 0.0121 0.019 0.0158
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0088 0.006 0.0114
Brugia malayi Protein kinase domain containing protein 0.012 0.0184 0.0152
Schistosoma mansoni rap gtpase-activating protein 0.0121 0.019 0.0872
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0274 0.1336
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0141 0.0266 0.0271
Onchocerca volvulus 0.0141 0.0266 0.0276
Onchocerca volvulus Putative alcohol dehydrogenase 0.0087 0.0055 0.0053
Onchocerca volvulus 0.1301 0.4786 0.5038
Schistosoma mansoni hypothetical protein 0.0141 0.0266 0.1291
Mycobacterium ulcerans thioesterase TesA 0.1161 0.4238 0.5384
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.016 0.0341 0.0386
Leishmania major protein kinase A catalytic subunit 0.0109 0.0141 0.0987
Trypanosoma brucei protein kinase, putative 0.0127 0.0214 0.1921
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.012 0.0184 0.1308
Leishmania major protein kinase A catalytic subunit isoform 2 0.0109 0.0141 0.0987
Loa Loa (eye worm) hypothetical protein 0.0214 0.055 0.0623
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0127 0.0214 0.0242
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0921 0.3305 0.4183
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0087 0.0055 0.0062
Brugia malayi serine/threonine-protein kinase PAK 7 0.0233 0.0624 0.0594
Schistosoma mansoni protein kinase C mu 0.0095 0.0088 0.031
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0085 0.0048 0.0055
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0109 0.0141 0.1238
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0214 0.055 0.0637
Mycobacterium ulcerans thioesterase 0.1161 0.4238 0.5384
Leishmania major oxidoreductase, putative 0.0087 0.0055 0.0348
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0088 0.006 0.0472
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0214 0.8018
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.035 0.1079 0.1898
Giardia lamblia Kinase, AGC PKA 0.0109 0.0141 0.0987
Mycobacterium tuberculosis Conserved protein 0.042 0.1352 0.1669
Trypanosoma cruzi acyl transferase-like protein, putative 0.0088 0.006 0.0487
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0109 0.0141 0.1102
Giardia lamblia Kinase, CMGC GSK 0.0127 0.0214 0.1532
Brugia malayi STE20-like kinase MST 0.0281 0.0813 0.0784
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0087 0.0055 0.0436
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0088 0.006 0.0114
Loa Loa (eye worm) AGC/PKA protein kinase 0.0109 0.0141 0.0159
Brugia malayi intracellular kinase 0.0127 0.0214 0.0183
Schistosoma mansoni zinc binding dehydrogenase 0.0087 0.0055 0.0126
Trypanosoma brucei oxidoreductase, putative 0.0087 0.0055 0.0436
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0109 0.0141 0.1238
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0379 0.1919
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0214 0.055 0.0637
Echinococcus granulosus NADH dehydrogenase 0.0141 0.0266 0.2081
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0127 0.0214 0.1921
Schistosoma mansoni alcohol dehydrogenase 0.0087 0.0055 0.0126
Plasmodium vivax hypothetical protein, conserved 0.02 0.0495 0.4335
Echinococcus granulosus serine:threonine protein kinase N2 0.0198 0.0487 0.3817
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0438 0.1422 0.1759
Plasmodium vivax acyl carrier protein, putative 0.0141 0.0266 0.2108
Echinococcus granulosus serine:threonine protein kinase N2 0.0156 0.0324 0.2539
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0088 0.006 0.0028
Trypanosoma cruzi oxidoreductase, putative 0.0087 0.0055 0.0436
Mycobacterium ulcerans Type I modular polyketide synthase 0.1393 0.5143 0.6547
Entamoeba histolytica hypothetical protein 0.012 0.0184 0.6869
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0087 0.0055 0.0436
Schistosoma mansoni acyl carrier protein 0.0141 0.0266 0.1291
Loa Loa (eye worm) hypothetical protein 0.078 0.2757 0.3122
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0141 0.0266 0.0271
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0214 0.055 0.0637
Echinococcus multilocularis death associated protein kinase 1 0.0992 0.358 1
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0121 0.019 0.053
Schistosoma mansoni [ACP] S-malonyltransferase 0.0088 0.006 0.0156
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0127 0.0214 0.1532
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0088 0.006 0.0007
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.035 0.1079 0.1319
Schistosoma mansoni protein kinase 0.0164 0.0356 0.179
Giardia lamblia Kinase, CMGC CLK 0.0085 0.0048 0.0301
Loa Loa (eye worm) hypothetical protein 0.0083 0.004 0.0045
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0141 0.0266 0.2406
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0087 0.0055 0.0023
Mycobacterium ulcerans fatty acid synthase Fas 0.0438 0.1422 0.1759
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.1479 0.548 0.6981
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.04 0.1277 0.3567
Mycobacterium ulcerans acyl carrier protein 0.0141 0.0266 0.0271
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0563 0.1911 0.2389
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0184 0.0839
Loa Loa (eye worm) hypothetical protein 0.0087 0.0055 0.0062
Loa Loa (eye worm) hypothetical protein 0.0074 0.0004 0.0005
Mycobacterium ulcerans polyketide synthase Pks13 0.2082 0.7826 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.1393 0.5143 0.6547
Echinococcus multilocularis NADH dehydrogenase 0.0141 0.0266 0.0742
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0095 0.0088 0.0056
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0111 0.015 0.042
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0157 0.0328 0.0372
Echinococcus granulosus cyclin dependent kinase 19 0.017 0.0379 0.2972
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0921 0.3305 0.4183
Echinococcus granulosus protein kinase shaggy 0.0127 0.0214 0.1675
Leishmania major zinc binding dehydrogenase-like protein 0.0087 0.0055 0.0348
Echinococcus multilocularis cyclin dependent kinase 19 0.017 0.0379 0.106
Trypanosoma cruzi oxidoreductase, putative 0.0087 0.0055 0.0436
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0487 0.2515
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.1479 0.548 0.6981
Echinococcus multilocularis serine:threonine protein kinase 3 0.0281 0.0813 0.2272
Chlamydia trachomatis acyl carrier protein 0.0141 0.0266 0.2016
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0143 0.0274 0.2144
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0141 0.0266 0.0742
Brugia malayi Alcohol dehydrogenase class III 0.0087 0.0055 0.0023
Echinococcus multilocularis dual specificity 0.012 0.0184 0.0513
Echinococcus multilocularis dual specificity protein kinase clk2 0.0085 0.0048 0.0135
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.035 0.1079 0.3015
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0141 0.0266 0.0271
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.04 0.1277 0.1446
Loa Loa (eye worm) hypothetical protein 0.0087 0.0055 0.0062
Onchocerca volvulus 0.0175 0.0401 0.0418
Brugia malayi hypothetical protein 0.0121 0.019 0.0158
Brugia malayi cyclin-dependent kinase 7 homolog 0.0114 0.0163 0.0132
Loa Loa (eye worm) hypothetical protein 0.0087 0.0055 0.0062
Echinococcus multilocularis 0.0157 0.0328 0.0917
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0274 0.1336
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0428 0.1386 0.1713
Echinococcus multilocularis cyclin dependent kinase 7 0.0105 0.0126 0.0353
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0087 0.0055 0.0436
Onchocerca volvulus 0.0127 0.0214 0.0221
Echinococcus granulosus rho-associated protein kinase 1 0.0188 0.0449 0.352
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.1139 0.4154 0.5275
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0048 0.0091
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0141 0.0266 0.0301
Loa Loa (eye worm) AMP-binding enzyme family protein 0.1301 0.4786 0.542
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.034 0.1043 0.1272
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0109 0.0141 0.1238
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0805 0.4268
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.035 0.1079 0.8454
Brugia malayi C1-like domain containing protein 0.0095 0.0088 0.0056
Echinococcus granulosus dual specificity protein kinase clk2 0.0085 0.0048 0.0379
Schistosoma mansoni protein kinase 0.0164 0.0356 0.179
Onchocerca volvulus 0.0121 0.019 0.0196
Echinococcus granulosus cyclin dependent kinase 9 0.0076 0.0014 0.0111
Brugia malayi Phosphopantetheine attachment site family protein 0.0141 0.0266 0.0235
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.035 0.1079 1
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0121 0.019 0.1697
Mycobacterium ulcerans polyketide synthase MbtD 0.0428 0.1386 0.1713
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.1121 0.4083 0.5183
Trypanosoma cruzi oxidoreductase, putative 0.0087 0.0055 0.0436
Echinococcus granulosus Vam6:Vps39 protein 0.0121 0.019 0.1487
Loa Loa (eye worm) TK/ALK protein kinase 0.0291 0.0852 0.0965
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0048 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0032 0.0178
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.035 0.1079 0.1222
Leishmania major protein kinase A catalytic subunit isoform 1 0.0109 0.0141 0.0987
Toxoplasma gondii quinone oxidoreductase, putative 0.0087 0.0055 0.0012
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0214 0.8018
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.2082 0.7826 1
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0141 0.0266 0.0271
Mycobacterium tuberculosis Polyketide synthase Pks2 0.135 0.4976 0.6333
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0214 0.0551 0.1539
Loa Loa (eye worm) hypothetical protein 0.0087 0.0055 0.0062
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0087 0.0055 0.0348
Echinococcus granulosus cyclin dependent kinase 7 0.0105 0.0126 0.0989
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0904 0.3237 0.5871
Loa Loa (eye worm) hypothetical protein 0.0109 0.0141 0.0159
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0085 0.0048 0.0377
Entamoeba histolytica PH domain containing protein kinase, putative 0.0111 0.015 0.5592
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0121 0.019 0.0872
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0127 0.0214 0.0305
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0085 0.0048 0.0377
Loa Loa (eye worm) hypothetical protein 0.0266 0.0752 0.0851
Leishmania major acyl carrier protein, putative 0.0141 0.0266 0.1918
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.1301 0.4786 0.6089
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0204 0.0514 0.4023
Mycobacterium tuberculosis Probable thioesterase TesA 0.1161 0.4238 0.5384
Schistosoma mansoni [ACP] S-malonyltransferase 0.0088 0.006 0.0156
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.012 0.0184 0.1641
Toxoplasma gondii acyl transferase domain-containing protein 0.0088 0.006 0.0022
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.035 0.1079 1
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.035 0.1079 1
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0438 0.1422 0.1759
Mycobacterium ulcerans polyketide synthase MbtC 0.035 0.1079 0.1319
Entamoeba histolytica protein kinase domain containing protein 0.012 0.0184 0.6869
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.012 0.0184 0.0208
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0204 0.0514 0.0582
Toxoplasma gondii type I fatty acid synthase 0.0214 0.055 0.0923
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0204 0.0514 0.0483
Loa Loa (eye worm) fatty acid synthase 0.1374 0.507 0.5742
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0141 0.0601
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0088 0.006 0.0168
Loa Loa (eye worm) acyl carrier protein 0.0141 0.0266 0.0301
Entamoeba histolytica acyl-CoA synthetase, putative 0.0141 0.0266 1
Loa Loa (eye worm) thyroid receptor interactor 0.0086 0.0054 0.0061
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0141 0.0266 0.0271
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.015 0.1059
Echinococcus multilocularis serine:threonine protein kinase N2 0.0156 0.0324 0.0906
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.035 0.1079 0.1319
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0085 0.0048 0.0377
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0204 0.0514 0.0537
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0143 0.0274 0.0311
Loa Loa (eye worm) hypothetical protein 0.234 0.8831 1
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0096 0.0092 0.0723
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0087 0.0055 0.0436
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0143 0.0274 0.2149
Echinococcus granulosus AMP dependent ligase 0.0141 0.0266 0.2081
Trichomonas vaginalis conserved hypothetical protein 0.042 0.1352 1
Brugia malayi Fes/CIP4 homology domain containing protein 0.0086 0.0054 0.0022
Onchocerca volvulus 0.0081 0.0032 0.0029
Brugia malayi Protein kinase domain containing protein 0.016 0.0341 0.031
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.1393 0.5143 0.6547
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0133 0.0237 0.0268
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.1479 0.548 0.6981
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.1393 0.5143 0.6547
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0141 0.0266 0.0271
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.04 0.1277 1
Loa Loa (eye worm) gastrulation defective protein 1 0.0157 0.0331 0.0375
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0109 0.0141 0.0393
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0087 0.0055 0.0348
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0141 0.0266 0.2406
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.1479 0.548 0.6981
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0109 0.0141 0.0393
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0141 0.0266 0.2059
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0792 0.2802 0.3535
Treponema pallidum acyl carrier protein 0.0141 0.0266 0.5
Onchocerca volvulus 0.0188 0.0449 0.0469
Schistosoma mansoni protein kinase 0.04 0.1277 0.6874
Mycobacterium leprae Polyketide synthase Pks13 0.2082 0.7826 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0134 0.0238 0.1866
Loa Loa (eye worm) hypothetical protein 0.0107 0.0135 0.0153
Loa Loa (eye worm) hypothetical protein 0.025 0.0691 0.0783
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.035 0.1079 0.1051
Brugia malayi Protein kinase domain containing protein 0.0291 0.0852 0.0823
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0111 0.015 0.1177
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0075 0.0008 0.0154
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0075 0.0008 0.0154
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0121 0.019 0.0872
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.017 0.0379 0.043
Schistosoma mansoni protein kinase 0.0157 0.0328 0.1637
Loa Loa (eye worm) hypothetical protein 0.0074 0.0004 0.0005
Brugia malayi Protein kinase domain containing protein 0.0204 0.0514 0.0483
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.135 0.4976 0.6333
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0266 0.0752 0.5889
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0214 0.0551 0.4314
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0141 0.0266 0.0271
Mycobacterium ulcerans polyketide synthase 0.1393 0.5143 0.6547
Toxoplasma gondii AGC kinase 0.0109 0.0141 0.017
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0085 0.0048 0.0377
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0087 0.0055 0.194
Mycobacterium ulcerans hypothetical protein 0.0141 0.0266 0.0271
Echinococcus multilocularis protein kinase shaggy 0.0127 0.0214 0.0597
Trypanosoma cruzi acyl transferase-like protein 0.0088 0.006 0.0487
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0113 0.016 0.0128
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0204 0.0514 0.0582
Entamoeba histolytica PH domain containing protein kinase, putative 0.0111 0.015 0.5592
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0141 0.0266 0.0271
Schistosoma mansoni tyrosine kinase 0.0276 0.0792 0.4196
Loa Loa (eye worm) AGC/PKA protein kinase 0.0109 0.0141 0.0159
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0127 0.0214 0.1005
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0109 0.0141 0.1238
Echinococcus multilocularis serine:threonine protein kinase N2 0.0198 0.0487 0.1361
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0048 0.0301
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0087 0.0055 0.0436
Loa Loa (eye worm) hypothetical protein 0.0121 0.019 0.0215
Loa Loa (eye worm) hypothetical protein 0.0214 0.055 0.0623
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0141 0.0266 0.0271
Onchocerca volvulus Fatty acid synthase homolog 0.2511 0.9497 1
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0105 0.0126 0.0143
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0127 0.0214 0.1675
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0109 0.0141 0.0895
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0127 0.0214 0.0597
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.1393 0.5143 0.5127
Schistosoma mansoni vam6/vps39 related 0.0121 0.019 0.0872
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0134 0.0238 0.0666
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0141 0.0987
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0141 0.0266 0.0271
Mycobacterium ulcerans Type I modular polyketide synthase 0.1393 0.5143 0.6547
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0087 0.0055 0.0012
Schistosoma mansoni hypothetical protein 0.0121 0.019 0.0872
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0141 0.0266 0.0276
Schistosoma mansoni ste20-related kinase 0.0219 0.0571 0.298
Echinococcus granulosus acyl carrier protein mitochondrial 0.0141 0.0266 0.2081
Brugia malayi AMP-binding enzyme family protein 0.1301 0.4786 0.477
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0121 0.019 0.1487
Schistosoma mansoni tyrosine kinase 0.0264 0.0745 0.3935
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0141 0.0601
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0143 0.0274 0.0766
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.02 0.0495 0.4335
Leishmania major hypothetical protein, conserved 0.042 0.1352 1
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0087 0.0055 0.0023
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0087 0.0055 0.0436
Brugia malayi AMP-binding enzyme family protein 0.0428 0.1386 0.1358
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0109 0.0141 0.017

Activities

Activity type Activity value Assay description Source Reference
Ki (functional) > 4 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDC2L6 ChEMBL. No reference
Ki (functional) = 6.1 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDK8 ChEMBL. No reference
Ki (functional) = 6.5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PIM1 ChEMBL. No reference
Ki (functional) = 6.9 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: ALK ChEMBL. No reference
Ki (functional) = 7 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CSNK1A1 ChEMBL. No reference
Ki (functional) = 7.4 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MAP4K4 ChEMBL. No reference
Ki (functional) = 7.4 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PKN2 ChEMBL. No reference
Ki (functional) = 7.5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CAMK2D ChEMBL. No reference
Ki (functional) = 7.7 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: SYK ChEMBL. No reference
Ki (functional) = 7.7 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PRKX ChEMBL. No reference
Ki (functional) = 7.8 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MINK ChEMBL. No reference
Ki (functional) = 7.8 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: ROCK2 ChEMBL. No reference
Ki (functional) = 7.8 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PRKACA ChEMBL. No reference
Ki (functional) = 7.9 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: GSK3A ChEMBL. No reference
Ki (functional) = 7.9 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: DAPK3 ChEMBL. No reference
Ki (functional) = 8.1 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PAK4 ChEMBL. No reference
Ki (functional) = 8.2 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: DYRK1A ChEMBL. No reference
Ki (functional) = 8.2 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: STK17A ChEMBL. No reference
Ki (functional) = 8.3 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PRKCN ChEMBL. No reference
Ki (functional) = 8.3 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: GSK3B ChEMBL. No reference
Ki (functional) = 8.3 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MAP4K5 ChEMBL. No reference
Ki (functional) = 8.4 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: JAK2 ChEMBL. No reference
Ki (functional) = 8.4 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CLK2 ChEMBL. No reference
Ki (functional) = 8.5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: STK3 ChEMBL. No reference
Ki (functional) = 8.5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: JAK3 ChEMBL. No reference
Ki (functional) = 8.5 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDK7 ChEMBL. No reference
Ki (functional) = 8.6 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDC7 ChEMBL. No reference
Ki (functional) = 8.7 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MAP4K2 ChEMBL. No reference
Ki (functional) = 8.7 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDK9 ChEMBL. No reference
Ki (functional) = 8.8 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDK2 ChEMBL. No reference
Ki (functional) = 8.8 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: MELK ChEMBL. No reference
Ki (functional) = 9 PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: RPS6KA3 ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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