Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Echinococcus multilocularis | integrin beta 2 | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma japonicum | ko:K06464 integrin beta 2, putative | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Loa Loa (eye worm) | integrin beta-2 | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Brugia malayi | Integrin beta pat-3 precursor | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Echinococcus granulosus | integrin beta 2 | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma japonicum | Integrin beta-3 precursor, putative | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma japonicum | Integrin beta-PS precursor, putative | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma mansoni | integrin beta subunit | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.044 | 0.8712 | 0.8707 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0365 | 0.6929 | 0.8753 |
Brugia malayi | Protein kinase c protein 2 | 0.0419 | 0.8217 | 1 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0494 | 1 | 1 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0352 | 0.6622 | 0.6609 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 0.6622 | 0.8363 |
Entamoeba histolytica | protein kinase, putative | 0.0076 | 0.0039 | 0.5 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0076 | 0.0039 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0406 | 0.791 | 1 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0142 | 0.1595 | 0.1562 |
Echinococcus granulosus | protein kinase c iota type | 0.013 | 0.1328 | 0.1293 |
Echinococcus multilocularis | protein kinase c iota type | 0.013 | 0.1328 | 0.1293 |
Entamoeba histolytica | protein kinase, putative | 0.0076 | 0.0039 | 0.5 |
Schistosoma mansoni | integrin beta subunit | 0.0223 | 0.3534 | 0.3508 |
Echinococcus granulosus | integrin beta 2 | 0.028 | 0.4906 | 0.4886 |
Toxoplasma gondii | AGC kinase | 0.0076 | 0.0039 | 0.5 |
Brugia malayi | Integrin beta pat-3 precursor | 0.0378 | 0.7246 | 0.8812 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0142 | 0.1595 | 0.1562 |
Schistosoma mansoni | atypical protein kinase C | 0.013 | 0.1328 | 0.1293 |
Entamoeba histolytica | protein kinase, putative | 0.0076 | 0.0039 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0076 | 0.0039 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0352 | 0.6622 | 0.6609 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0142 | 0.1595 | 0.1977 |
Echinococcus granulosus | protein kinase C gamma type | 0.044 | 0.8712 | 0.8707 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0494 | 1 | 1 |
Loa Loa (eye worm) | integrin beta-2 | 0.0378 | 0.7246 | 0.9156 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0142 | 0.1595 | 0.1562 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0494 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Echinococcus multilocularis | integrin beta 2 | 0.028 | 0.4906 | 0.4886 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0352 | 0.6622 | 0.6609 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Brugia malayi | protein kinase C II. | 0.0142 | 0.1595 | 0.1903 |
Trichomonas vaginalis | AGC family protein kinase | 0.0076 | 0.0039 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.