Detailed information for compound 1624880

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 542.149 | Formula: C32H44ClNO4
  • H donors: 1 H acceptors: 1 LogP: 10.06 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCCc1c2[n+](CCc3c2cc(O)c(c3)OCCC)cc2c1ccc(c2OCCC)OC.[Cl-]
  • InChi: 1S/C32H43NO4.ClH/c1-5-8-9-10-11-12-13-25-24-14-15-29(35-4)32(37-19-7-3)27(24)22-33-17-16-23-20-30(36-18-6-2)28(34)21-26(23)31(25)33;/h14-15,20-22H,5-13,16-19H2,1-4H3;1H
  • InChiKey: XDPNWNHYWISILQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Bromodomain containing protein 0.0041 0.0124 0.0129
Leishmania major hypothetical protein, conserved 0.0077 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.006 0.0231 0.0239
Echinococcus granulosus dnaJ subfamily B 0.0457 0.2403 0.2403
Loa Loa (eye worm) hypothetical protein 0.0028 0.0051 0.0053
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0022 0.0018 0.0019
Schistosoma mansoni inositol monophosphatase 0.0112 0.0511 0.0511
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0084 0.0084
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0187 0.0923 0.0923
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.025 0.1268 0.1268
Loa Loa (eye worm) hypothetical protein 0.0115 0.0529 0.0549
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0065 0.0253 0.0712
Schistosoma mansoni cpg binding protein 0.0036 0.0096 0.0096
Schistosoma mansoni tar DNA-binding protein 0.0066 0.026 0.026
Schistosoma mansoni neprilysin-2 (M13 family) 0.0286 0.1465 0.1465
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0084 0.0084
Loa Loa (eye worm) peptidase family M13 containing protein 0.0418 0.2192 0.2272
Loa Loa (eye worm) hypothetical protein 0.0065 0.0253 0.0263
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0097
Loa Loa (eye worm) RNA binding protein 0.0066 0.026 0.0269
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0702 0.3747 0.3747
Echinococcus multilocularis neuroligin 0.0035 0.0094 0.0094
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0065 0.0253 0.0412
Plasmodium vivax dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative 0.0065 0.0253 0.0352
Loa Loa (eye worm) hypothetical protein 0.0246 0.1245 0.129
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0053 0.0189 0.0196
Loa Loa (eye worm) hypothetical protein 0.0065 0.0253 0.0263
Plasmodium falciparum dihydrolipoamide acyltransferase component E2 0.0065 0.0253 0.0352
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0097
Brugia malayi Carboxylesterase family protein 0.0035 0.0094 0.0097
Echinococcus multilocularis microtubule associated protein 2 0.0672 0.3582 0.3582
Schistosoma mansoni hypothetical protein 0.0148 0.0709 0.0709
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0018 0.0019
Entamoeba histolytica hypothetical protein 0.0109 0.0498 0.3072
Brugia malayi PHD-finger family protein 0.003 0.0063 0.0065
Leishmania major dihydrolipoamide acetyltransferase precursorlike protein 0.0065 0.0253 0.0253
Brugia malayi Pax transcription activation domain interacting protein 0.0022 0.0018 0.0019
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0307 0.0819
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.003 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0307 0.0499
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.026 0.0269
Toxoplasma gondii 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein 0.0065 0.0253 0.0253
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0286 0.1465 0.1465
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0307 0.0307
Schistosoma mansoni hypothetical protein 0.005 0.0176 0.0176
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0065 0.0253 0.0676
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0319 0.0443
Schistosoma mansoni topbp1 0.0022 0.0018 0.0018
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.017 0.0176
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.025 0.1268 0.1268
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0035 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0428 0.2246 0.2328
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0159 0.0772 0.08
Echinococcus granulosus microtubule associated protein 2 0.0672 0.3582 0.3582
Schistosoma mansoni survival motor neuron protein 0.005 0.0174 0.0174
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0022 0.0018 0.003
Plasmodium falciparum carbamoyl phosphate synthetase 0.0159 0.0769 0.1067
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1334 0.7209 1
Loa Loa (eye worm) carboxylesterase 0.021 0.1048 0.1086
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0154 0.0154
Brugia malayi Inositol-1 0.0112 0.0511 0.0529
Mycobacterium ulcerans glutaminase 0.1749 0.9479 1
Trypanosoma cruzi acetyl-CoA carboxylase 0.1142 0.6153 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0051 0.0137
Loa Loa (eye worm) hypothetical protein 0.0047 0.0157 0.0163
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E2 0.0065 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0074 0.0307 0.0318
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0155 0.0155
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0307 0.0307
Brugia malayi peptidase family M13 containing protein 0.0138 0.0655 0.0679
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0154 0.0154
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0511 0.0511
Schistosoma mansoni hypothetical protein 0.005 0.0176 0.0176
Trichomonas vaginalis glutaminase, putative 0.1749 0.9479 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0051 0.0054
Trypanosoma brucei dihydrolipoamide acetyltransferase E2 subunit, putative 0.0065 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0428 0.2246 0.2328
Brugia malayi hypothetical protein 0.0022 0.0018 0.0019
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0189 0.0196
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0153 0.0737 0.0737
Mycobacterium ulcerans zinc metalloprotease 0.0566 0.3002 0.3166
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0155 0.0155
Onchocerca volvulus 0.0074 0.0307 0.2035
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0337 0.1748 0.1748
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0084 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0084 0.0084
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0236 0.1193 0.1237
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.025 0.1268 0.3385
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0286 0.1465 0.1465
Schistosoma mansoni hypothetical protein 0.0048 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0074 0.0307 0.0318
Trypanosoma cruzi FHA domain containing protein, putative 0.0022 0.0018 0.003
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.025 0.1268 0.3353
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0112 0.0511 0.3148
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0013 0.0018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0236 0.1193 0.1193
Loa Loa (eye worm) hypothetical protein 0.0109 0.0496 0.0514
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0022 0.0018 0.0019
Echinococcus granulosus Biotin lipoyl attachment 0.0065 0.0253 0.0253
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1334 0.7209 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0337 0.1748 0.2841
Toxoplasma gondii biotin-requiring enzyme domain-containing protein 0.0065 0.0253 0.0253
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0428 0.2246 0.2328
Mycobacterium leprae probable zinc metalloprotease 0.0566 0.3002 0.8001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0019
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.1844 1 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0094 0.0094
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0511 0.0511
Onchocerca volvulus 0.0281 0.1436 1
Echinococcus multilocularis replication factor c subunit 1 0.0022 0.0018 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0051 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0028 0.0051 0.0053
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0122 0.0751
Trypanosoma brucei dihydrolipoamide branched chain transacylase, putative 0.0065 0.0253 0.0253
Schistosoma mansoni hypothetical protein 0.0048 0.016 0.016
Echinococcus multilocularis protein patched 0.0049 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0418 0.2192 0.2272
Loa Loa (eye worm) TAR-binding protein 0.0066 0.026 0.0269
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0176 0.0176
Onchocerca volvulus 0.0032 0.0075 0.0403
Echinococcus multilocularis survival motor neuron protein 1 0.0246 0.1245 0.1245
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0702 0.3747 0.3747
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0511 0.083
Loa Loa (eye worm) hypothetical protein 0.005 0.0175 0.0182
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0051 0.0088
Schistosoma mansoni transcription factor LCR-F1 0.0109 0.0498 0.0498
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.0175 0.0175
Schistosoma mansoni tar DNA-binding protein 0.0066 0.026 0.026
Entamoeba histolytica hypothetical protein 0.0022 0.0018 0.0113
Entamoeba histolytica acyl-coA synthetase, putative 0.0028 0.0051 0.0316
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0075 0.0078
Brugia malayi DKFZp564C0469 protein 0.0022 0.0018 0.0019
Schistosoma mansoni hypothetical protein 0.005 0.0176 0.0176
Mycobacterium ulcerans branched-chain alpha-keto acid dehydrogenase subunit E2 0.0065 0.0253 0.0267
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.021 0.1048 0.1048
Loa Loa (eye worm) peptidase family M13 containing protein 0.0418 0.2192 0.2272
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0189 0.0189
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0019
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.025 0.1268 0.1338
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0154 0.0154
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.025 0.1268 0.3385
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0051 0.0054
Loa Loa (eye worm) acetyltransferase 0.0153 0.0737 0.0764
Mycobacterium tuberculosis Carboxylesterase LipT 0.0035 0.0094 0.025
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0702 0.3747 0.3953
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0307 0.0318
Schistosoma mansoni hypothetical protein 0.0109 0.0498 0.0498
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0307 0.0307
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0189 0.0189
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0702 0.3747 0.3747
Echinococcus granulosus neuroligin 0.0035 0.0094 0.0094
Brugia malayi Carboxylesterase family protein 0.0035 0.0094 0.0097
Schistosoma mansoni hypothetical protein 0.0148 0.0709 0.0709
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0176 0.0176
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.025 0.1268 0.3353
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0112 0.0511 0.0539
Trypanosoma brucei acetyl-CoA carboxylase 0.1844 1 1
Treponema pallidum pyruvate carboxylase subunit B 0.0065 0.0253 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0051 0.0316
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0319 0.0519
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0307 0.0324
Trypanosoma cruzi dihydrolipoamide acetyltransferase, putative 0.0065 0.0253 0.0412
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0019
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0307 0.0819
Loa Loa (eye worm) zinc metallopeptidase 4 0.0138 0.0655 0.0679
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0065 0.0253 0.0253
Mycobacterium ulcerans beta-lactamase 0.0074 0.0307 0.0324
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0279 0.0279
Echinococcus granulosus acetylcholinesterase 0.021 0.1048 0.1048
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0319 0.0519
Plasmodium vivax lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative 0.0065 0.0253 0.0352
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.016 0.0259
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0035 0.0094 0.0099
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0702 0.3747 0.3953
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.025 0.1268 0.3353
Brugia malayi hypothetical protein 0.0246 0.1245 0.129
Toxoplasma gondii histone lysine methyltransferase SET1 0.0068 0.0272 0.0272
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0159 0.0769 0.2053
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0154 0.0154
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.025 0.1268 0.2061
Schistosoma mansoni hypothetical protein 0.0048 0.016 0.016
Schistosoma mansoni endothelin-converting enzyme-related 0.0138 0.0655 0.0655
Loa Loa (eye worm) glutaminase 0.1749 0.9479 0.9827
Loa Loa (eye worm) hypothetical protein 0.0566 0.3002 0.3112
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0138 0.0655 0.0655
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.1844 1 1
Loa Loa (eye worm) hypothetical protein 0.0418 0.2192 0.2272
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0094 0.0094
Schistosoma mansoni aspartate carbamoyltransferase 0.0159 0.0769 0.0769
Onchocerca volvulus 0.0035 0.0094 0.0531
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0702 0.3747 0.3953
Brugia malayi mbt repeat family protein 0.0046 0.0154 0.016
Brugia malayi glutaminase DH11.1 0.1749 0.9479 0.9827
Loa Loa (eye worm) hypothetical protein 0.0418 0.2192 0.2272
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0159 0.0769 0.0769
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.025 0.1268 0.1338
Schistosoma mansoni hypothetical protein 0.005 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.1844 1 1
Brugia malayi acetyltransferase, GNAT family protein 0.0153 0.0737 0.0764
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0065 0.0253 0.0412
Onchocerca volvulus 0.0035 0.0094 0.0531
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0159 0.0772 0.08
Trichomonas vaginalis spcc417.12 protein, putative 0.0035 0.0094 0.0099
Brugia malayi hypothetical protein 0.0035 0.0094 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0175 0.0175
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0051 0.0053
Schistosoma mansoni hypothetical protein 0.0148 0.0709 0.0709
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0307 0.0307
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0314 0.1622 1
Mycobacterium ulcerans lipase LipD 0.0074 0.0307 0.0324
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0337 0.1748 0.2841
Echinococcus multilocularis dnaJ subfamily B 0.0457 0.2403 0.2403
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0236 0.1193 0.1193
Onchocerca volvulus 0.005 0.0174 0.1098
Entamoeba histolytica hypothetical protein 0.0109 0.0498 0.3072
Mycobacterium ulcerans hypothetical protein 0.0028 0.0051 0.0054
Echinococcus granulosus replication factor c subunit 1 0.0022 0.0018 0.0018
Mycobacterium ulcerans hypothetical protein 0.0074 0.0307 0.0324
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0019
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0155 0.0215
Schistosoma mansoni hypothetical protein 0.0034 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0007 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0236 0.1193 0.1193
Trypanosoma brucei pyruvate dehydrogenase complex E3 binding protein, putative 0.0065 0.0253 0.0253
Plasmodium falciparum dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 0.0065 0.0253 0.0352
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0065 0.0253 0.0412
Schistosoma mansoni hypothetical protein 0.005 0.0174 0.0174
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0176 0.0176
Echinococcus granulosus Protein patched homolog 1 0.0049 0.017 0.017
Schistosoma mansoni tar DNA-binding protein 0.0066 0.026 0.026
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0286 0.1465 0.1465
Loa Loa (eye worm) PHD-finger family protein 0.002 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0319 0.0331
Echinococcus multilocularis inositol monophosphatase 1 0.0112 0.0511 0.0511
Schistosoma mansoni hypothetical protein 0.0286 0.1467 0.1467
Leishmania major hypothetical protein, conserved 0.0074 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0428 0.2246 0.2328
Loa Loa (eye worm) hypothetical protein 0.0566 0.3002 0.3112
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0248 0.0257
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0307 0.0324
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.025 0.1268 0.1268
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0286 0.1465 0.1465
Echinococcus multilocularis Niemann Pick C1 protein 0.0164 0.0799 0.0799
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0115 0.0529 0.3262
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0007 0.0018
Entamoeba histolytica hypothetical protein 0.0109 0.0498 0.3072
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0176 0.0182
Onchocerca volvulus 0.0035 0.0094 0.0531
Onchocerca volvulus 0.0035 0.0094 0.0531
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.025 0.1268 0.1338
Schistosoma mansoni bromodomain containing protein 0.0067 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.0074 0.0307 0.0318
Loa Loa (eye worm) carboxylesterase 0.0035 0.0094 0.0097
Schistosoma mansoni hypothetical protein 0.0457 0.2403 0.2403
Leishmania major dihydrolipoamide acetyltransferase precursor, putative 0.0065 0.0253 0.0253
Echinococcus granulosus tumor protein p63 0.0351 0.1822 0.1822
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0051 0.0054
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0204 0.0211
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0112 0.0511 0.0511
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0155 0.0155
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0307 0.0324
Loa Loa (eye worm) hypothetical protein 0.0281 0.1436 0.1489
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.0175 0.0175
Echinococcus granulosus BC026374 protein S09 family 0.0035 0.0094 0.0094
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.021 0.1048 0.1086
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0122 0.0169
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.025 0.1268 0.1338
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1748 0.9475 0.9475
Echinococcus granulosus inositol monophosphatase 1 0.0112 0.0511 0.0511
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0307 0.0819
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.0159 0.0769 0.125
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0187 0.0923 0.0923
Echinococcus multilocularis endothelin converting enzyme 1 0.0566 0.3002 0.3002
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0307 0.0819
Brugia malayi Carboxyl transferase domain containing protein 0.1779 0.9646 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0155 0.0163
Schistosoma mansoni inositol monophosphatase 0.0112 0.0511 0.0511
Plasmodium vivax replication factor C subunit 1, putative 0.0022 0.0018 0.0025
Loa Loa (eye worm) MBCTL1 0.0053 0.0189 0.0196
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0051 0.0053
Loa Loa (eye worm) hypothetical protein 0.0418 0.2192 0.2272
Schistosoma mansoni neprilysin 0.0148 0.0709 0.0709
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0051 0.0316
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0065 0.0253 0.0253
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0314 0.1622 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.016 0.0774 0.0774
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0022 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0018 0.0019
Brugia malayi latrophilin 2 splice variant baaae 0.0109 0.0496 0.0514
Echinococcus granulosus cpg binding protein 0.0036 0.0096 0.0096
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0112 0.0511 0.0539
Echinococcus granulosus survival motor neuron protein 1 0.0246 0.1245 0.1245
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0566 0.3002 0.3002
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0307 0.0307
Mycobacterium leprae Probable biotinylated protein homolog TB7.3 0.0065 0.0253 0.0631
Leishmania major carboxylase, putative 0.0702 0.3747 0.3747
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0013 0.0014
Brugia malayi Pre-SET motif family protein 0.0231 0.1166 0.1208
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.016 0.0259
Brugia malayi Carboxylesterase family protein 0.021 0.1048 0.1086
Brugia malayi Bromodomain containing protein 0.0079 0.033 0.0342
Echinococcus multilocularis protein dispatched 1 0.0056 0.0208 0.0208
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0065 0.0253 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0018 0.0019
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0065 0.0253 0.0712
Mycobacterium tuberculosis Probable branched-chain keto acid dehydrogenase E2 component BkdC 0.0065 0.0253 0.0676
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0065 0.0253 0.0412
Onchocerca volvulus 0.0074 0.0307 0.2035
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0319 0.0443
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.025 0.1268 0.1338
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0236 0.1193 0.1193
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.01 0.0447 0.1192
Echinococcus multilocularis nibrin 0.0022 0.0018 0.0018
Echinococcus granulosus expressed conserved protein 0.0108 0.0491 0.0491
Brugia malayi Peptidase family M13 containing protein 0.0566 0.3002 0.3112
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.025 0.1268 0.3385
Loa Loa (eye worm) hypothetical protein 0.005 0.0176 0.0182
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0307 0.0324
Onchocerca volvulus 0.0028 0.0051 0.0232
Schistosoma mansoni chromosome transmission fidelity factor 0.0022 0.0018 0.0018
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0159 0.0772 0.08
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0065 0.0253 0.0263
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0022 0.0018 0.0019
Trichomonas vaginalis replication factor C large subunit, putative 0.0022 0.0018 0.0019
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0138 0.0655 0.0655
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0138 0.0655 0.0655
Mycobacterium ulcerans pyruvate carboxylase 0.0702 0.3747 0.3953
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0022 0.0018 0.0113
Loa Loa (eye worm) hypothetical protein 0.0065 0.0253 0.0263
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0307 0.0499
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0159 0.0769 0.0769
Schistosoma mansoni cpg binding protein 0.0036 0.0096 0.0096
Mycobacterium ulcerans hypothetical protein 0.0178 0.0873 0.0921
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0566 0.3002 0.3112
Loa Loa (eye worm) hypothetical protein 0.0028 0.0051 0.0053
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.003 0.003
Trichomonas vaginalis inositol monophosphatase, putative 0.0112 0.0511 0.0539
Leishmania major dihydrolipoamide branched chain transacylase, putative 0.0065 0.0253 0.0253
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.016 0.0259
Brugia malayi Niemann-Pick C1 protein precursor 0.0115 0.0529 0.0549
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0702 0.3747 0.3747
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0051 0.0054
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0065 0.0253 0.0253
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.025 0.1268 0.1338
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0065 0.0253 0.0263
Schistosoma mansoni hypothetical protein 0.0507 0.2678 0.2678
Echinococcus multilocularis tar DNA binding protein 0.0066 0.026 0.026
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0022 0.0018 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Mycobacterium tuberculosis Conserved protein 0.0074 0.0307 0.0819
Schistosoma mansoni zinc finger protein 0.0025 0.0034 0.0034
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0051 0.0051
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0307 0.0426
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0022 0.0018 0.0019
Mycobacterium tuberculosis Conserved protein 0.0074 0.0307 0.0819
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0475 0.2501 0.6676
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0236 0.1193 0.1193
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0097
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0035 0.0094 0.025
Leishmania major carbamoyl-phosphate synthase, putative 0.0159 0.0769 0.0769
Echinococcus multilocularis Niemann Pick C1 protein 0.0115 0.0529 0.0529
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0007 0.0018
Chlamydia trachomatis biotin carboxylase 0.0638 0.3393 1
Leishmania major acetyl-CoA carboxylase, putative 0.1844 1 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0109 0.0498 0.0498
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0189 0.0189
Echinococcus granulosus zinc finger protein 0.0025 0.0034 0.0034
Echinococcus granulosus tar DNA binding protein 0.0066 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0049 0.017 0.0176
Brugia malayi RNA binding protein 0.0066 0.026 0.0269
Schistosoma mansoni hypothetical protein 0.0148 0.0709 0.0709
Loa Loa (eye worm) hypothetical protein 0.021 0.1048 0.1086
Plasmodium falciparum lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 0.0065 0.0253 0.0352
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.016 0.0774 0.1259
Echinococcus granulosus Niemann Pick C1 protein 0.0164 0.0799 0.0799
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0051 0.0051
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.1779 0.9646 1
Mycobacterium tuberculosis Biotinylated protein TB7.3 0.0065 0.0253 0.0676
Trichomonas vaginalis set domain proteins, putative 0.0263 0.134 0.1413
Brugia malayi Carboxylesterase family protein 0.0035 0.0094 0.0097
Mycobacterium ulcerans hypothetical protein 0.0065 0.0253 0.0267
Brugia malayi Pre-SET motif family protein 0.0034 0.0084 0.0088
Trichomonas vaginalis esterase, putative 0.0074 0.0307 0.0324
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0307 0.0324
Echinococcus granulosus endothelin converting enzyme 1 0.0566 0.3002 0.3002
Echinococcus multilocularis Biotin lipoyl attachment 0.0065 0.0253 0.0253
Entamoeba histolytica hypothetical protein 0.0109 0.0498 0.3072
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0566 0.3002 0.8011
Echinococcus multilocularis tumor protein p63 0.0351 0.1822 0.1822
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.025 0.1268 0.3714
Echinococcus multilocularis expressed conserved protein 0.0108 0.0491 0.0491
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0307 0.0318
Plasmodium vivax SET domain protein, putative 0.0034 0.0084 0.0117
Echinococcus multilocularis para nitrobenzyl esterase 0.0035 0.0094 0.0094
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0028 0.0051 0.0054
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.017 0.017
Echinococcus granulosus geminin 0.0507 0.2678 0.2678
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.017 0.0179
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.017 0.017
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0307 0.0774
Schistosoma mansoni topbp1 0.0022 0.0018 0.0018
Chlamydia trachomatis dihydrolipoamide acetyltransferase 0.0065 0.0253 0.0712
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0058 0.0216 0.0352
Chlamydia trachomatis DNA ligase 0.0022 0.0018 0.0016
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.025 0.1268 0.1268
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide acyltransferase E2 component 0.0065 0.0253 0.0676
Echinococcus multilocularis acetylcholinesterase 0.021 0.1048 0.1048
Brugia malayi hypothetical protein 0.0077 0.0319 0.0331
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.026 0.0269
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0097
Echinococcus multilocularis carboxylesterase 5A 0.021 0.1048 0.1048
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0511 0.083
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0138 0.0655 0.0655
Echinococcus multilocularis zinc finger protein 0.0025 0.0034 0.0034
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0176 0.0182
Schistosoma mansoni hypothetical protein 0.0507 0.2678 0.2678
Schistosoma mansoni hypothetical protein 0.0109 0.0496 0.0496
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0018 0.0019
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0248 0.0248
Mycobacterium ulcerans carboxylesterase, LipT 0.0035 0.0094 0.0099
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0065 0.0253 0.0412
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0702 0.3747 1
Echinococcus multilocularis cpg binding protein 0.0036 0.0096 0.0096
Schistosoma mansoni tar DNA-binding protein 0.0066 0.026 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0018 0.0019
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.025 0.1268 0.1268
Treponema pallidum DNA ligase (lig) 0.0022 0.0018 0.0723
Loa Loa (eye worm) hypothetical protein 0.0074 0.0307 0.0318
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0018 0.003
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0035 0.0094 0.0094
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0154 0.0154
Schistosoma mansoni patched 1 0.0049 0.017 0.017
Echinococcus multilocularis acetylcholinesterase 0.021 0.1048 0.1048
Schistosoma mansoni glutaminase 0.1749 0.9479 0.9479
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0065 0.0253 0.0253
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0307 0.0819
Mycobacterium leprae Probable lipase LipE 0.0074 0.0307 0.0774
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.016 0.0774 0.0774
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0112 0.0511 0.0539
Toxoplasma gondii hypothetical protein 0.0054 0.0198 0.0198
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0065 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0097
Schistosoma mansoni pyruvate carboxylase 0.0702 0.3747 0.3747
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.01 0.0447 0.1149
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0028 0.0051 0.0054
Brugia malayi Carboxylesterase family protein 0.0035 0.0094 0.0097
Loa Loa (eye worm) hypothetical protein 0.0428 0.2246 0.2328
Loa Loa (eye worm) hypothetical protein 0.0069 0.0277 0.0287
Loa Loa (eye worm) beta-lactamase 0.0074 0.0307 0.0318
Loa Loa (eye worm) hypothetical protein 0.0046 0.0154 0.016
Schistosoma mansoni tar DNA-binding protein 0.0066 0.026 0.026
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0088 0.0088
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.0159 0.0769 0.0769
Onchocerca volvulus 0.0046 0.0154 0.0958
Onchocerca volvulus 0.0035 0.0094 0.0531
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0065 0.0253 0.0267
Echinococcus granulosus histone acetyltransferase KAT2B 0.0146 0.0701 0.0701
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0154 0.0154
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0248 0.0262
Toxoplasma gondii ABC1 family protein 0.0074 0.0307 0.0307
Plasmodium falciparum replication factor C subunit 1, putative 0.0022 0.0018 0.0025
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0702 0.3747 0.609
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0122 0.0751
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.1166 0.1208
Leishmania major propionyl-coa carboxylase beta chain, putative 0.025 0.1268 0.1268
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0154 0.016
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0091 0.0091
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0112 0.0511 0.1363
Loa Loa (eye worm) hypothetical protein 0.0074 0.0307 0.0318
Brugia malayi follicle stimulating hormone receptor 0.0235 0.1187 0.1231
Brugia malayi hypothetical protein 0.0022 0.0018 0.0019
Echinococcus multilocularis BC026374 protein (S09 family) 0.0035 0.0094 0.0094
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0028 0.0051 0.0137
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0117 0.0539 0.0539
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0702 0.3747 0.3747
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0007 0.0018
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0022 0.0018 0.0018
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0174 0.018
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0091 0.0091
Brugia malayi mbt repeat family protein 0.0046 0.0154 0.016
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0181 0.0181
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0307 0.0324
Mycobacterium tuberculosis Conserved hypothetical protein 0.0178 0.0873 0.2331
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0065 0.0253 0.0253
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.025 0.1268 0.1268
Onchocerca volvulus 0.0263 0.134 0.9319
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0307 0.0819
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0155 0.0163
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0154 0.0958
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Echinococcus granulosus GPCR family 2 0.005 0.0176 0.0176
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0065 0.0253 0.0412
Giardia lamblia Replication factor C, subunit 1 0.0022 0.0018 0.0113
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0065 0.0253 0.0253
Loa Loa (eye worm) inositol-1 0.0112 0.0511 0.0529
Brugia malayi Carboxylesterase family protein 0.021 0.1048 0.1086
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0109 0.0498 0.0498
Echinococcus multilocularis GPCR, family 2 0.005 0.0176 0.0176
Brugia malayi CHE-14 protein 0.0049 0.017 0.0176
Brugia malayi hypothetical protein 0.0109 0.0498 0.0517
Toxoplasma gondii ATPase, AAA family protein 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.002 0.001 0.001
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0702 0.3747 0.3747
Echinococcus granulosus Niemann Pick C1 protein 0.0115 0.0529 0.0529
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0043 0.0137 0.0142
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0235 0.1187 0.1231
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0248 0.0248
Schistosoma mansoni hypothetical protein 0.0148 0.0709 0.0709
Loa Loa (eye worm) hypothetical protein 0.0428 0.2246 0.2328
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0138 0.0655 0.0655
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0148 0.0709 0.0709
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.0159 0.0769 0.125
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0307 0.0324
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0236 0.1193 0.1193
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0236 0.1193 0.1237
Toxoplasma gondii pyruvate carboxylase 0.0702 0.3747 0.3747
Brugia malayi TAR-binding protein 0.0066 0.026 0.0269
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0065 0.0253 0.0631
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0319 0.0319
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.025 0.1268 0.2061
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0236 0.1193 0.1193
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0702 0.3747 1
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0702 0.3747 1
Toxoplasma gondii dihydrolipoamide acyltransferase, putative 0.0065 0.0253 0.0253
Brugia malayi beta-lactamase family protein 0.0074 0.0307 0.0318
Chlamydia trachomatis acetyl-CoA carboxylase biotin carboxyl carrier protein 0.0065 0.0253 0.0712
Leishmania major mitochondrial DNA polymerase beta 0.0337 0.1748 0.1748
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0074 0.0074
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0702 0.3747 1
Onchocerca volvulus 0.0051 0.0181 0.1147
Toxoplasma gondii peptidase family M13 protein 0.0566 0.3002 0.3002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0104 0.0108
Onchocerca volvulus 0.0074 0.0307 0.2035
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0013 0.0018
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0248 0.0248
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0051 0.0088
Schistosoma mansoni acetyl-CoA carboxylase 0.1844 1 1
Echinococcus granulosus nibrin 0.0022 0.0018 0.0018
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0088 0.0088
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.025 0.1268 0.2061
Loa Loa (eye worm) carboxylesterase 0.0035 0.0094 0.0097
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0065 0.0253 0.0253
Brugia malayi Latrophilin receptor protein 2 0.005 0.0176 0.0182
Echinococcus granulosus para nitrobenzyl esterase 0.0035 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0074 0.0307 0.0318
Schistosoma mansoni hypothetical protein 0.0048 0.016 0.016
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0248 0.0662
Schistosoma mansoni microtubule-associated protein tau 0.0672 0.3582 0.3582
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0307 0.0819
Echinococcus granulosus acetylcholinesterase 0.021 0.1048 0.1048
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0702 0.3747 0.3747
Mycobacterium tuberculosis Conserved protein 0.0074 0.0307 0.0819
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0159 0.0769 0.1067
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0189 0.0189
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0035 0.0094 0.0094
Brugia malayi Calcitonin receptor-like protein seb-1 0.0159 0.0772 0.08
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0154 0.0154
Schistosoma mansoni gliotactin 0.0035 0.0094 0.0094
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0153 0.0737 0.0737
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0097
Echinococcus granulosus carboxylesterase 5A 0.021 0.1048 0.1048
Toxoplasma gondii carbamoylphosphate synthetase 0.0159 0.0769 0.0769
Loa Loa (eye worm) hypothetical protein 0.0051 0.0181 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0018 0.003
Onchocerca volvulus 0.0034 0.0084 0.0467
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0051 0.0051
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0248 0.0262
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0319 0.0443
Loa Loa (eye worm) acetylcholinesterase 1 0.021 0.1048 0.1086
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0013 0.0034
Schistosoma mansoni DNA ligase IV 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0148 0.0709 0.0709
Wolbachia endosymbiont of Brugia malayi branched-chain alpha-keto acid dehydrogenase subunit E2 0.0065 0.0253 0.0676
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0035 0.0094 0.025
Schistosoma mansoni neuroligin 3 (S09 family) 0.0035 0.0094 0.0094
Brugia malayi topoisomerase 0.0022 0.0018 0.0019
Schistosoma mansoni BC026374 protein (S09 family) 0.0035 0.0094 0.0094
Echinococcus multilocularis geminin 0.0507 0.2678 0.2678
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0189 0.0189
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0051 0.0054
Schistosoma mansoni acetylcholinesterase 0.0035 0.0094 0.0094
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0702 0.3747 0.609
Brugia malayi hypothetical protein 0.0049 0.0171 0.0177
Trypanosoma brucei unspecified product 0.0462 0.2429 0.2429
Loa Loa (eye worm) glutaminase 2 0.1749 0.9479 0.9827
Brugia malayi beta-lactamase family protein 0.0074 0.0307 0.0318
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0097
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0176 0.0176
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0022 0.0018 0.0019
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0065 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0566 0.3002 0.3112
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0065 0.0253 0.0253
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0022 0.0018 0.0019
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0159 0.0769 0.0811
Brugia malayi CXXC zinc finger family protein 0.0032 0.0075 0.0078
Schistosoma mansoni cpg binding protein 0.0032 0.0075 0.0075
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0065 0.0253 0.0253
Brugia malayi beta-lactamase 0.0074 0.0307 0.0318

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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