Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | nervana 2 | 0.0371 | 0.5991 | 0.8899 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0194 | 0.2904 | 0.4166 |
Brugia malayi | Uncoordinated protein 104 | 0.0037 | 0.0186 | 0.0186 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0602 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0194 | 0.2904 | 0.4166 |
Onchocerca volvulus | 0.0037 | 0.0186 | 1 | |
Leishmania major | protein kinase, putative | 0.0041 | 0.0259 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.2904 | 0.2769 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0194 | 0.2904 | 0.4166 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0087 | 0.1056 | 0.1069 |
Brugia malayi | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0057 | 0.0534 | 0.0533 |
Brugia malayi | GTP-ase activating protein for Arf containing protein | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Brugia malayi | Dynamin | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Toxoplasma gondii | calcium dependent protein kinase CDPK7 | 0.0041 | 0.0259 | 0.0211 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0201 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Onchocerca volvulus | Putative zinc finger protein | 0.0037 | 0.0186 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0194 | 0.2904 | 0.4166 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.1056 | 0.1656 |
Toxoplasma gondii | hypothetical protein | 0.0037 | 0.0186 | 0.0133 |
Loa Loa (eye worm) | Plekhf2 protein | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | Plekhf2 protein | 0.0037 | 0.0186 | 0.0186 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0371 | 0.5991 | 0.8899 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0087 | 0.1056 | 0.1334 |
Echinococcus granulosus | protein kinase C gamma type | 0.0194 | 0.2904 | 0.4166 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK21, putative | 0.0041 | 0.0259 | 0.0111 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.1056 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | uncoordinated protein 104 | 0.0037 | 0.0186 | 0.0186 |
Onchocerca volvulus | 0.0037 | 0.0186 | 1 | |
Entamoeba histolytica | protein kinase, putative | 0.0565 | 0.9354 | 0.9354 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0087 | 0.1056 | 1 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0375 | 0.6064 | 0.901 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0037 | 0.0186 | 0.0206 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0194 | 0.2904 | 0.4166 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0194 | 0.2904 | 0.4166 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0413 | 0.6709 | 1 |
Trichomonas vaginalis | ribosomal protein S6 kinase, 90kD, polypeptide, putative | 0.0041 | 0.0259 | 0.0074 |
Brugia malayi | Syntrophin-1 | 0.0037 | 0.0186 | 0.0186 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0371 | 0.5991 | 0.8899 |
Trypanosoma brucei | serine/threonine-protein kinase NrkA | 0.0041 | 0.0259 | 0.0074 |
Plasmodium falciparum | PH domain-containing protein, putative | 0.0037 | 0.0186 | 0.0206 |
Brugia malayi | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0194 | 0.2904 | 0.2904 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0041 | 0.0259 | 0.0259 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0194 | 0.2904 | 0.4166 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0057 | 0.0534 | 0.5056 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0087 | 0.1056 | 0.1069 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | TBC domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | pleckstrin homology (PH) domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | RhoGEF domain-containing protein | 0.0037 | 0.0186 | 0.0186 |
Onchocerca volvulus | Putative neuronal RhoA GEF protein | 0.0037 | 0.0186 | 1 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0057 | 0.0534 | 1 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0194 | 0.2904 | 0.4166 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0375 | 0.6064 | 0.901 |
Trypanosoma brucei | Serine/threonine-protein kinase NEK21, putative | 0.0041 | 0.0259 | 0.0074 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0037 | 0.0186 | 0.0186 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.003 | 0.0063 | 0.0593 |
Brugia malayi | MAX-1A | 0.0037 | 0.0186 | 0.0186 |
Onchocerca volvulus | 0.0037 | 0.0186 | 1 | |
Trypanosoma cruzi | serine/threonine protein kinase, putative | 0.0041 | 0.0259 | 0.0111 |
Trypanosoma cruzi | NEK family Serine/threonine-protein kinase, putative | 0.0041 | 0.0259 | 0.0111 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0194 | 0.2904 | 0.2904 |
Leishmania major | serine/threonine-protein kinase a, putative | 0.0041 | 0.0259 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0037 | 0.0186 | 0.0206 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0413 | 0.6709 | 1 |
Entamoeba histolytica | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Onchocerca volvulus | 0.0037 | 0.0186 | 1 | |
Onchocerca volvulus | outspread protein homolog | 0.0037 | 0.0186 | 1 |
Brugia malayi | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | GTP-ase activating protein for Arf containing protein | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | protein kinase, putative | 0.0041 | 0.0259 | 0.0259 |
Brugia malayi | Oxysterol-binding protein | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0602 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0602 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK21, putative | 0.0041 | 0.0259 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0507 | 0.0507 |
Plasmodium vivax | PH domain containing protein | 0.0037 | 0.0186 | 0.0206 |
Brugia malayi | Probable ClpP-like protease | 0.0087 | 0.1056 | 0.1056 |
Plasmodium vivax | conserved Plasmodium protein, unknown function | 0.0037 | 0.0186 | 0.0206 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0194 | 0.2904 | 0.2904 |
Brugia malayi | Oxysterol binding protein | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | Protein kinase domain containing protein | 0.0194 | 0.2904 | 0.2904 |
Brugia malayi | GTP-ase activating protein for Arf containing protein | 0.0037 | 0.0186 | 0.0186 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK17, putative | 0.0041 | 0.0259 | 0.0111 |
Onchocerca volvulus | Protein melted homolog | 0.0037 | 0.0186 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0375 | 0.6064 | 0.901 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Plasmodium falciparum | oxysterol-binding protein, putative | 0.0037 | 0.0186 | 0.0206 |
Toxoplasma gondii | protein kinase domain-containing protein | 0.0041 | 0.0259 | 0.0211 |
Onchocerca volvulus | 0.0037 | 0.0186 | 1 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.2904 | 0.2769 |
Loa Loa (eye worm) | cytohesin 3 | 0.0037 | 0.0186 | 0.0186 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0194 | 0.2904 | 0.4166 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0413 | 0.6709 | 1 |
Brugia malayi | Hr1 repeat family protein | 0.0194 | 0.2904 | 0.2904 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0194 | 0.2904 | 0.4166 |
Loa Loa (eye worm) | rho-GTPase-activating | 0.0037 | 0.0186 | 0.0186 |
Trypanosoma cruzi | serine/threonine-protein kinase NRKB, putative | 0.0041 | 0.0259 | 0.0111 |
Brugia malayi | GTPase-activator protein for Ras-like GTPase containing protein | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Toxoplasma gondii | phosphatidylinositol transfer protein | 0.0037 | 0.0186 | 0.0133 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0041 | 0.0259 | 0.0259 |
Trypanosoma brucei | serine/threonine-protein kinase NRKB, putative | 0.0041 | 0.0259 | 0.0074 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0087 | 0.1056 | 0.1334 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Entamoeba histolytica | protein kinase, putative | 0.0041 | 0.0259 | 0.0259 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0194 | 0.2904 | 0.4166 |
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.2904 | 0.2904 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0037 | 0.0186 | 0.0186 |
Echinococcus multilocularis | nervana 2 | 0.0371 | 0.5991 | 0.8899 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0037 | 0.0186 | 0.0186 |
Plasmodium vivax | oxysterol-binding protein/PH domain containing protein | 0.0037 | 0.0186 | 0.0206 |
Echinococcus granulosus | nervana 2 | 0.0371 | 0.5991 | 0.8899 |
Schistosoma mansoni | serine/threonine kinase | 0.0194 | 0.2904 | 0.4166 |
Plasmodium falciparum | calcium-dependent protein kinase 7 | 0.0041 | 0.0259 | 0.0327 |
Trichomonas vaginalis | 3-phosphoinositide dependent protein kinase-1, putative | 0.0041 | 0.0259 | 0.0074 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0041 | 0.0259 | 0.0259 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Brugia malayi | Dynamin | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | Pleckstrin Homology Domain | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0194 | 0.2904 | 0.4166 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0413 | 0.6709 | 0.6709 |
Plasmodium vivax | calcium-dependent protein kinase 7, putative | 0.0041 | 0.0259 | 0.0327 |
Loa Loa (eye worm) | syntrophin-1 | 0.0037 | 0.0186 | 0.0186 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0413 | 0.6709 | 1 |
Entamoeba histolytica | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Toxoplasma gondii | hypothetical protein | 0.0037 | 0.0186 | 0.0133 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.1056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.1056 | 0.1056 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0057 | 0.0534 | 1 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.1056 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0259 | 0.0259 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0194 | 0.2904 | 0.4166 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0201 | 0.0201 |
Entamoeba histolytica | protein kinase, putative | 0.0041 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0602 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0041 | 0.0259 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0371 | 0.5991 | 0.8899 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | probable spectrin beta chain | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0194 | 0.2904 | 0.4166 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | Variant SH3 domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0087 | 0.1056 | 0.1334 |
Brugia malayi | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Trypanosoma brucei | NEK family Serine/threonine-protein kinase, putative | 0.0041 | 0.0259 | 0.0074 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0507 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0201 | 0.0201 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0259 | 0.0259 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0037 | 0.0186 | 0.0186 |
Trypanosoma cruzi | NIMA-related kinase, putative | 0.0041 | 0.0259 | 0.0111 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0371 | 0.5991 | 0.8899 |
Entamoeba histolytica | protein kinase, putative | 0.0041 | 0.0259 | 0.0259 |
Trypanosoma cruzi | NIMA-related kinase, putative | 0.0041 | 0.0259 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0375 | 0.6064 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Plasmodium falciparum | phosphatidylinositol transfer protein, putative | 0.0037 | 0.0186 | 0.0206 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0194 | 0.2904 | 0.4166 |
Leishmania major | protein kinase, putative,serine/threonine protein kinase, putative | 0.0041 | 0.0259 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | protein kinase, putative | 0.0602 | 1 | 1 |
Loa Loa (eye worm) | GTP-ase activating protein for Arf containing protein | 0.0037 | 0.0186 | 0.0186 |
Onchocerca volvulus | 0.0037 | 0.0186 | 1 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0507 | 0.0507 |
Brugia malayi | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0194 | 0.2904 | 0.2904 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0194 | 0.2904 | 0.4166 |
Toxoplasma gondii | Oxysterol-binding protein | 0.0037 | 0.0186 | 0.0133 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0194 | 0.2904 | 0.4166 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0087 | 0.1056 | 0.1656 |
Echinococcus granulosus | protein kinase c iota type | 0.0194 | 0.2904 | 0.4166 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0194 | 0.2904 | 0.4166 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0186 | 0.0206 |
Trypanosoma cruzi | Protein kinase B | 0.0413 | 0.6709 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0371 | 0.5991 | 0.8899 |
Toxoplasma gondii | AtPH1 family protein | 0.0037 | 0.0186 | 0.0133 |
Plasmodium falciparum | acylated pleckstrin-homology domain-containing protein, putative | 0.0037 | 0.0186 | 0.0206 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK17, putative | 0.0041 | 0.0259 | 0.0111 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.0507 | 0.0507 |
Entamoeba histolytica | ARF GTPase activating protein, putative | 0.0037 | 0.0186 | 0.0186 |
Onchocerca volvulus | 0.0037 | 0.0186 | 1 | |
Echinococcus granulosus | NDR protein kinase | 0.0194 | 0.2904 | 0.4166 |
Entamoeba histolytica | p21-activated kinase | 0.0041 | 0.0259 | 0.0259 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0375 | 0.6064 | 0.901 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Entamoeba histolytica | protein kinase 2, putative | 0.0375 | 0.6064 | 0.6064 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0194 | 0.2904 | 0.2904 |
Brugia malayi | Variant SH3 domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | PH domain-containing protein | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0602 | 1 | 1 |
Entamoeba histolytica | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0602 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Loa Loa (eye worm) | oxysterol binding protein | 0.0037 | 0.0186 | 0.0186 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0413 | 0.6709 | 1 |
Leishmania major | folate/biopterin transporter, putative | 0.0041 | 0.0259 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0194 | 0.2904 | 0.4166 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0186 | 0.7196 |
Onchocerca volvulus | Abnormal cell migration protein 10 homolog | 0.0037 | 0.0186 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0041 | 0.0259 | 0.0074 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0602 | 1 | 1 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0037 | 0.0186 | 0.0186 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0194 | 0.2904 | 0.4166 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0057 | 0.0534 | 0.0533 |
Brugia malayi | Protein kinase domain containing protein | 0.0194 | 0.2904 | 0.2904 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.1056 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0037 | 0.0186 | 0.0186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.3549 | 0.3427 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0186 | 0.7196 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | protein kinase, putative | 0.0194 | 0.2904 | 0.2904 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.0189 | 0.2831 | 0.2695 |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.2904 | 0.2769 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0194 | 0.2904 | 0.4166 |
Brugia malayi | Cadps2 protein | 0.0037 | 0.0186 | 0.0186 |
Leishmania major | protein kinase, putative | 0.0041 | 0.0259 | 1 |
Giardia lamblia | Kinase, AGC PKA | 0.0375 | 0.6064 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Toxoplasma gondii | AGC kinase | 0.0565 | 0.9354 | 1 |
Brugia malayi | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Brugia malayi | Cytohesin 3 | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0041 | 0.0259 | 0.0111 |
Brugia malayi | protein kinase C II. | 0.0194 | 0.2904 | 0.2904 |
Entamoeba histolytica | protein kinase, putative | 0.0041 | 0.0259 | 0.0259 |
Echinococcus multilocularis | protein kinase c iota type | 0.0194 | 0.2904 | 0.4166 |
Brugia malayi | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0194 | 0.2904 | 0.4166 |
Leishmania major | rac serine-threonine kinase, putative,protein kinase, putative | 0.0041 | 0.0259 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0194 | 0.2904 | 0.4166 |
Trichomonas vaginalis | AGC family protein kinase | 0.0602 | 1 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.1056 | 0.5 |
Brugia malayi | PH domain containing protein | 0.0037 | 0.0186 | 0.0186 |
Entamoeba histolytica | protein kinase, putative | 0.0602 | 1 | 1 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0375 | 0.6064 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.1056 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0602 | 1 | 1 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0565 | 0.9354 | 0.9354 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0565 | 0.9354 | 0.9354 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0413 | 0.6709 | 0.6709 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0194 | 0.2904 | 0.2904 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0041 | 0.0259 | 0.0259 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.921 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.9 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.754 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.696 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.675 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.619 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.546 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.533 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.473 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.356 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.