Detailed information for compound 162702

Basic information

Technical information
  • TDR Targets ID: 162702
  • Name: benzyl N-[(2S)-4-amino-1-[[(2S,3S)-3-hydroxy- 4-[methylcarbamoyl(2-methylpropyl)amino]-1-ph enylbutan-2-yl]amino]-1,4-dioxobutan-2-yl]car bamate
  • MW: 541.639 | Formula: C28H39N5O6
  • H donors: 5 H acceptors: 5 LogP: 1.73 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 2
  • SMILES: CNC(=O)N(C[C@@H]([C@@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)CC(=O)N)Cc1ccccc1)O)CC(C)C
  • InChi: 1S/C28H39N5O6/c1-19(2)16-33(27(37)30-3)17-24(34)22(14-20-10-6-4-7-11-20)31-26(36)23(15-25(29)35)32-28(38)39-18-21-12-8-5-9-13-21/h4-13,19,22-24,34H,14-18H2,1-3H3,(H2,29,35)(H,30,37)(H,31,36)(H,32,38)/t22-,23-,24-/m0/s1
  • InChiKey: KGHZDRBKSVQHQS-HJOGWXRNSA-N  

Network

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Synonyms

  • benzyl N-[(1S)-3-amino-1-[[(1S,2S)-1-benzyl-2-hydroxy-3-[isobutyl(methylcarbamoyl)amino]propyl]carbamoyl]-3-oxo-propyl]carbamate
  • N-[(1S)-3-amino-1-[[[(1S,2S)-1-benzyl-2-hydroxy-3-[isobutyl(methylcarbamoyl)amino]propyl]amino]-oxomethyl]-3-oxopropyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-4-azanyl-1-[[(2S,3S)-3-hydroxy-4-[methylcarbamoyl(2-methylpropyl)amino]-1-phenyl-butan-2-yl]amino]-1,4-dioxo-butan-2-yl]carbamate
  • N-[(1S)-3-amino-1-[[(1S,2S)-1-benzyl-2-hydroxy-3-[isobutyl(methylcarbamoyl)amino]propyl]carbamoyl]-3-keto-propyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-4-amino-1-[[(2S,3S)-3-hydroxy-4-(methylcarbamoyl-(2-methylpropyl)amino)-1-phenylbutan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamate
  • phenylmethyl N-[(1S)-3-amino-1-[[(1S,2S)-2-hydroxy-3-(isobutyl-(methylcarbamoyl)amino)-1-(phenylmethyl)propyl]carbamoyl]-3-oxo-propyl]carbamate
  • N-[(1S)-3-amino-1-[[[(1S,2S)-2-hydroxy-3-(isobutyl-(methylcarbamoyl)amino)-1-(phenylmethyl)propyl]amino]-oxomethyl]-3-oxopropyl]carbamic acid phenylmethyl ester
  • N-[(1S)-3-amino-1-[[(1S,2S)-1-(benzyl)-2-hydroxy-3-(isobutyl-(methylcarbamoyl)amino)propyl]carbamoyl]-3-keto-propyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-4-amino-1-[[(2S,3S)-3-hydroxy-4-(methylcarbamoyl-(2-methylpropyl)amino)-1-phenyl-butan-2-yl]amino]-1,4-dioxo-butan-2-yl]carbamate
  • (Hydroxyethyl)urea Isostere deriv. 25

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis cathepsin L cysteine protease 0.0043 0.0133 0.0133
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0041 0.0125 0.0125
Echinococcus granulosus C type lectin domian containing protein 0.0067 0.0288 0.0346
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0581 0.0609
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0248 0.1433 0.1815
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0296 0.031
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0639 0.067
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Mycobacterium ulcerans proteasome PrcA 0.0248 0.1433 0.1759
Onchocerca volvulus 0.0043 0.0133 0.0153
Brugia malayi proteasome subunit alpha type 4 0.0248 0.1433 0.1823
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.0044 0.0046
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0248 0.1433 0.1502
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Echinococcus granulosus tumor protein p63 0.0213 0.1213 0.1455
Brugia malayi proteasome subunit alpha type 3 0.0248 0.1433 0.1823
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0073 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.005 0.0061
Leishmania major proteasome alpha 3 subunit, putative 0.0248 0.1433 0.179
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0073 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Brugia malayi Cyclin, N-terminal domain containing protein 0.0051 0.0188 0.0237
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0365 0.0462
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0034 0.004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0052 0.0192 0.023
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0056 0.0218 0.0256
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0101 0.0503 0.0603
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0248 0.1433 0.1502
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0029 0.005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Brugia malayi calpain family protein 1 0.0064 0.0268 0.0339
Brugia malayi calpain family protein 1 0.0064 0.0268 0.0339
Echinococcus granulosus subfamily T1A non peptidase ue 0.0248 0.1433 0.1719
Trichomonas vaginalis hypothetical protein 0.019 0.1066 0.1355
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0116 0.0145
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Brugia malayi proteasome subunit alpha type 1 0.0248 0.1433 0.1823
Giardia lamblia Proteasome subunit beta type 3 0.0248 0.1433 0.1759
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0039 0.011 0.0128
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0208 0.1179 0.1432
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0122 0.0639 0.0639
Brugia malayi ecdysone receptor 0.0065 0.0274 0.0346
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0248 0.1433 0.1823
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0547 0.3328 0.423
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0116 0.0121
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0481 0.0572
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus granulosus mitogen activated protein kinase 0.0036 0.0093 0.0111
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0248 0.1433 0.1823
Leishmania major trypanothione reductase 0.0091 0.044 0.0519
Brugia malayi nuclear hormone receptor family member odr-7 0.0065 0.0274 0.0346
Entamoeba histolytica cyclin family protein 0.0032 0.0066 0.0082
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0248 0.1433 0.1502
Brugia malayi Cathepsin L-like precursor 0.0028 0.0044 0.0053
Echinococcus granulosus calpain A 0.0067 0.0289 0.0346
Brugia malayi von Willebrand Factor 0.0039 0.011 0.0137
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0192 0.0242
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0093 0.0097
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0365 0.0388
Schistosoma mansoni cellular tumor antigen P53 0.0031 0.0061 0.0063
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0055 0.0066
Onchocerca volvulus 0.0079 0.0365 0.0553
Brugia malayi hypothetical protein 0.0113 0.0581 0.0738
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0063 0.0058
Onchocerca volvulus 0.013 0.0688 0.1108
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0557 0.0583
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0031
Trypanosoma brucei glucosidase, putative 0.0029 0.005 0.0061
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Echinococcus multilocularis lysosomal alpha glucosidase 0.0133 0.0705 0.0705
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Trypanosoma brucei hypothetical protein, conserved 0.0417 0.2505 0.3187
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.005 0.0061
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 1
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Echinococcus multilocularis proteasome subunit beta type 6 0.0248 0.1433 0.1433
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0231 0.1326 0.161
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0245 0.0257
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0093 0.0116
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0137 0.0734 0.0923
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis integrin alpha ps 0.0032 0.0065 0.0065
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0155 0.0119
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0068 0.0296 0.0296
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0068 0.0296 0.0355
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Brugia malayi nuclear receptor RXR 0.0065 0.0274 0.0346
Onchocerca volvulus 0.0283 0.1657 0.2774
Echinococcus granulosus lysine specific demethylase 5A 0.0104 0.0525 0.0629
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0248 0.1433 0.1502
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Leishmania major proteasome alpha 1 subunit, putative 0.0248 0.1433 0.179
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) G-protein coupled receptor 0.0071 0.0315 0.039
Loa Loa (eye worm) latrophilin receptor protein 2 0.0041 0.0125 0.0148
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0248 0.1433 0.1823
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Brugia malayi hypothetical protein 0.0065 0.0274 0.0346
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0248 0.1433 0.1823
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.005
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0045 0.015 0.015
Onchocerca volvulus 0.0046 0.0155 0.0192
Echinococcus granulosus tm gpcr rhodopsin 0.0071 0.0315 0.0378
Echinococcus granulosus membrane bound transcription factor site 1 0.0042 0.0129 0.0154
Schistosoma mansoni integrin alpha-ps 0.0066 0.0284 0.0298
Brugia malayi Steroid receptor seven-up type 2 0.0137 0.0734 0.0932
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0052 0.0192 0.0201
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0077 0.035 0.0526
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0639 0.067
Schistosoma mansoni hypothetical protein 0.0089 0.043 0.045
Brugia malayi neuroendocrine convertase 1 precursor 0.0617 0.3771 0.4799
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0064 0.0268 0.033
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Loa Loa (eye worm) intermediate filament protein 0.013 0.0688 0.0865
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0079 0.0365 0.0553
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0036 0.0093 0.0116
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0037 0.0096 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Treponema pallidum fructose-bisphosphate aldolase 0.0238 0.1373 1
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Leishmania major hypothetical protein, conserved 0.0417 0.2505 0.3159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi Nuclear hormone receptor-like 1 0.0137 0.0734 0.0932
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0071 0.0315 0.033
Trypanosoma brucei subtilisin peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni jumonji/arid domain-containing protein 0.0104 0.0525 0.0549
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Onchocerca volvulus 0.0039 0.011 0.0114
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Echinococcus multilocularis cyclin B 0.0051 0.0188 0.0188
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0155 0.0195
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni hypothetical protein 0.019 0.1066 0.1117
Onchocerca volvulus Neuropeptide F receptor homolog 0.0071 0.0315 0.0467
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0137 0.0734 0.1187
Entamoeba histolytica cyclin family protein 0.0032 0.0066 0.0082
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0248 0.1433 0.1433
Echinococcus granulosus biogenic amine 5HT receptor 0.0071 0.0315 0.0378
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0137 0.0734 0.0734
Giardia lamblia 20S proteasome alpha subunit 6 0.0248 0.1433 0.1759
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.1433 0.1815
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0073 0.009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0071 0.0315 0.033
Mycobacterium leprae 3-dehydroquinate dehydratase AroD (AroQ) (3-dehydroquinase) (Type II DHQase) 0.1162 0.7227 0.9193
Echinococcus granulosus SAM and MBT domain containing protein 0.004 0.0116 0.0139
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0063 0.0058
Brugia malayi GnHR receptor homolog 0.0071 0.0315 0.0399
Onchocerca volvulus 0.0071 0.0315 0.0467
Loa Loa (eye worm) proteasome subunit beta type 1 0.098 0.6073 0.7728
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0071 0.0315 0.0399
Onchocerca volvulus 0.0067 0.0288 0.0421
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0116 0.0601 0.0754
Brugia malayi proteasome subunit beta type 1 0.098 0.6073 0.773
Echinococcus multilocularis C type lectin domian containing protein 0.0067 0.0288 0.0288
Toxoplasma gondii ABC1 family protein 0.0079 0.0365 0.0444
Echinococcus multilocularis neuropeptide FF receptor 2 0.0071 0.0315 0.0315
Loa Loa (eye worm) melatonin receptor type 1A 0.0071 0.0315 0.039
Echinococcus granulosus histone acetyltransferase MYST2 0.0045 0.015 0.018
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0365 0.0388
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0078
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0248 0.1433 0.1823
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Toxoplasma gondii subtilisin SUB6 0.0042 0.0129 0.0142
Schistosoma mansoni integrin alpha-ps 0.0035 0.0082 0.0086
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0065 0.0274 0.0287
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0245 0.0234
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.005 0.0061
Echinococcus granulosus neuroendocrine convertase 2 0.0617 0.3771 0.4522
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0365 0.0383
Echinococcus granulosus cpg binding protein 0.0063 0.0263 0.0315
Mycobacterium tuberculosis Conserved protein 0.0079 0.0365 0.0388
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Echinococcus granulosus nuclear receptor nhr 48 0.0065 0.0274 0.0328
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0607 0.3711 0.3711
Loa Loa (eye worm) hypothetical protein 0.0032 0.0065 0.0071
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.1433 0.1823
Leishmania major mitochondrial DNA polymerase beta 0.0206 0.1168 0.1451
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Brugia malayi Will die slowly protein 0.0283 0.1657 0.2107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0137 0.0734 0.0923
Brugia malayi intermediate filament protein 0.013 0.0688 0.0873
Loa Loa (eye worm) hypothetical protein 0.0056 0.0218 0.0266
Brugia malayi photoreceptor-specific nuclear receptor 0.0137 0.0734 0.0932
Plasmodium vivax vivapain-2 0.0043 0.0133 0.0167
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0043 0.0133 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) neuropeptide F receptor 0.0071 0.0315 0.039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus granulosus cyclin B3 1 0.0032 0.0066 0.0079
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0155 0.0156
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0073 0.0323 0.0338
Echinococcus multilocularis g-protein coupled receptor 0.0071 0.0315 0.0315
Echinococcus granulosus tm gpcr rhodopsin 0.0071 0.0315 0.0378
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0071 0.0315 0.033
Echinococcus granulosus lamin 0.013 0.0688 0.0825
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0274 0.0328
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0245 0.0234
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0155 0.0195
Giardia lamblia G2/mitotic-specific cyclin B 0.0051 0.0188 0.0161
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0607 0.3711 0.445
Trypanosoma cruzi trypanothione reductase, putative 0.0091 0.044 0.0558
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0248 0.1433 0.1433
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0137 0.0734 0.0734
Loa Loa (eye worm) hypothetical protein 0.0041 0.0125 0.0148
Schistosoma mansoni opsin-like receptor 0.0071 0.0315 0.033
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0097 0.0481 0.061
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Onchocerca volvulus 0.0039 0.011 0.0114
Echinococcus multilocularis neuropeptides capa receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0041 0.0125 0.0125
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0155 0.0195
Echinococcus multilocularis citrate lyase subunit beta protein 0.0048 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0112 0.0574 0.0719
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi hypothetical protein 0.0073 0.0323 0.0409
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Plasmodium vivax proteasome subunit beta type-4, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0137 0.0734 0.0734
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0274 0.0274
Brugia malayi MH2 domain containing protein 0.0234 0.1348 0.1714
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Loa Loa (eye worm) calpain family protein 1 0.0045 0.0148 0.0176
Schistosoma mansoni lamin 0.013 0.0688 0.072
Echinococcus granulosus FTZ F1 alpha 0.0137 0.0734 0.088
Onchocerca volvulus 0.0071 0.0315 0.0467
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.001 0.001
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Trypanosoma cruzi cysteine peptidase, putative 0.0162 0.0891 0.1132
Echinococcus granulosus thyroid hormone receptor alpha 0.0065 0.0274 0.0328
Plasmodium vivax glutathione reductase, putative 0.0091 0.044 0.0558
Echinococcus multilocularis dro:myosuppressin receptor 0.0071 0.0315 0.0315
Plasmodium vivax SET domain protein, putative 0.0078 0.0358 0.0453
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0245 0.029
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis cysteine protease 0.0043 0.0133 0.0133
Schistosoma mansoni jumonji/arid domain-containing protein 0.0104 0.0525 0.0549
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0248 0.1433 0.1433
Onchocerca volvulus 0.0071 0.0315 0.0467
Onchocerca volvulus Cathepsin L homolog 0.0043 0.0133 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0137 0.0734 0.0932
Echinococcus multilocularis beta adrenergic receptor kinase 0.0109 0.0557 0.0557
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trypanosoma cruzi cruzipain precursor, putative 0.0162 0.0891 0.1132
Echinococcus granulosus g protein coupled receptor 0.0071 0.0315 0.0378
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Giardia lamblia Hypothetical protein 0.0032 0.0066 0.0004
Plasmodium vivax SET domain protein, putative 0.0122 0.0639 0.0811
Echinococcus multilocularis sex peptide receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis peptidase Clp (S14 family) 0.0037 0.0096 0.0096
Mycobacterium tuberculosis Conserved hypothetical protein 0.0108 0.0551 0.0626
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.013 0.0688 0.0865
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0248 0.1433 0.179
Trypanosoma brucei protein kinase, putative 0.0036 0.0093 0.0116
Schistosoma mansoni peptidase Clp (S14 family) 0.0056 0.0218 0.0228
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0071 0.0315 0.0315
Echinococcus granulosus proteasome subunit beta type 7 0.0248 0.1433 0.1719
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0256 0.1483 0.1553
Brugia malayi ORL1-like opioid receptor 0.0071 0.0315 0.0399
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Brugia malayi RNA binding protein 0.0191 0.1076 0.1368
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0034 0.0035
Loa Loa (eye worm) steroid hormone receptor 0.0137 0.0734 0.0923
Schistosoma mansoni opsin-like receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Schistosoma mansoni survival motor neuron protein 0.0091 0.0439 0.046
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0248 0.1433 0.1823
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0071 0.0315 0.0315
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0071 0.0315 0.033
Echinococcus granulosus voltage dependent calcium channel subunit 0.0039 0.011 0.0132
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Loa Loa (eye worm) endoprotease bli-4 0.0981 0.6082 0.7739
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.011 0.0137
Brugia malayi Pre-SET motif family protein 0.0122 0.0639 0.0811
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0121 0.0152
Brugia malayi sulfakinin receptor protein 0.0071 0.0315 0.0399
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0155 0.0119
Loa Loa (eye worm) hypothetical protein 0.006 0.0246 0.0302
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Plasmodium falciparum acyl-CoA synthetase 0.0034 0.0082 0.0101
Echinococcus multilocularis g protein coupled receptor 0.0071 0.0315 0.0315
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0066
Echinococcus granulosus cathepsin l cysteine peptidase 0.0043 0.0133 0.0159
Schistosoma mansoni nuclear receptor 0.0065 0.0274 0.0287
Brugia malayi GCC2 and GCC3 family protein 0.0067 0.0288 0.0365
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Echinococcus granulosus neuropeptide s receptor 0.036 0.2142 0.2569
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0248 0.1433 0.1719
Schistosoma mansoni neuropeptide f receptor 76f 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Onchocerca volvulus 0.0043 0.0133 0.0153
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0167 0.0171
Echinococcus multilocularis cyclin B3 1 0.0032 0.0066 0.0066
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni alpha-glucosidase 0.0114 0.0587 0.0615
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0041 0.0125 0.0157
Brugia malayi beta-lactamase family protein 0.0079 0.0365 0.0462
Echinococcus multilocularis integrin alpha ps 0.0066 0.0284 0.0284
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0245 0.027
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis WD repeat domain, putative 0.0283 0.1657 0.2107
Brugia malayi Thioredoxin reductase 0.0091 0.044 0.0558
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Echinococcus granulosus neuropeptides capa receptor 0.0071 0.0315 0.0378
Trypanosoma cruzi major cysteine proteinase, putative 0.0127 0.0671 0.0852
Echinococcus multilocularis neuropeptide receptor A26 0.036 0.2142 0.2142
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0029 0.0047 0.0057
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0232 0.1332 0.1395
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Echinococcus granulosus neuropeptide receptor 0.0575 0.351 0.421
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.004 0.0116 0.0124
Loa Loa (eye worm) RNA binding protein 0.0191 0.1076 0.136
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0176
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0063 0.0078
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0208 0.1179 0.1432
Toxoplasma gondii thioredoxin reductase 0.0091 0.044 0.0539
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0039 0.011 0.0137
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.1261 0.7856 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Brugia malayi proteasome subunit alpha type 6 0.0248 0.1433 0.1823
Leishmania major hypothetical protein, conserved 0.0079 0.0365 0.0424
Brugia malayi Dopamine receptor protein 2 0.0071 0.0315 0.0399
Echinococcus granulosus c4b binding protein beta chain 0.0067 0.0288 0.0346
Echinococcus granulosus GPCR family 2 0.0041 0.0125 0.015
Brugia malayi proteasome subunit alpha type 2 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable oxidoreductase 0.0231 0.1326 0.1621
Brugia malayi TAR-binding protein 0.0191 0.1076 0.1368
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0248 0.1433 0.1823
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0148 0.0802 0.1019
Onchocerca volvulus 0.0071 0.0315 0.0467
Leishmania major proteasome beta 2 subunit, putative 0.0607 0.3711 0.4701
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0034 0.0031
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Echinococcus granulosus furin 0.0981 0.6082 0.7294
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0152
Plasmodium vivax proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0063 0.0078
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0022 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Loa Loa (eye worm) CUTiclin-Like family member 0.0039 0.011 0.0128
Echinococcus granulosus allatostatin A receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis mitogen activated protein kinase 0.0036 0.0093 0.0093
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0063 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0137 0.0734 0.0932
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0378
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Brugia malayi putative neuropeptide receptor 0.0071 0.0315 0.0399
Mycobacterium tuberculosis Probable reductase 0.0208 0.1179 0.1432
Onchocerca volvulus 0.0043 0.0133 0.0153
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0248 0.1433 0.1823
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0121 0.0075
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0121 0.0152
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0073 0.009
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0248 0.1433 0.1759
Toxoplasma gondii subtilisin SUB9 0.0042 0.0129 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi proteasome subunit beta type 3 0.0248 0.1433 0.1823
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0048 0.0167 0.021
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0063 0.0078
Loa Loa (eye worm) mbt repeat family protein 0.004 0.0116 0.0135
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Onchocerca volvulus Bile acid receptor homolog 0.0137 0.0734 0.1187
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0073 0.0013
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0137 0.0734 0.0734
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0036 0.0093 0.0076
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0035 0.0087 0.0108
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0073 0.009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis thioredoxin glutathione reductase 0.0091 0.0442 0.0442
Entamoeba histolytica cyclin, putative 0.0032 0.0066 0.0082
Loa Loa (eye worm) hypothetical protein 0.0046 0.0155 0.0186
Leishmania major pyruvate kinase 0.0033 0.0073 0.005
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Schistosoma mansoni integrin alpha 0.0148 0.0803 0.0841
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0133 0.0167
Echinococcus multilocularis 0.0791 0.4879 0.4879
Trichomonas vaginalis set domain proteins, putative 0.0946 0.5858 0.7457
Echinococcus granulosus phd:f box containing protein 0.0027 0.0034 0.004
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0596 0.3642 0.4635
Schistosoma mansoni biogenic amine receptor 0.0071 0.0315 0.033
Echinococcus multilocularis histone acetyltransferase MYST2 0.0045 0.015 0.015
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0261
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0071 0.0315 0.0315
Brugia malayi latrophilin 2 splice variant baaae 0.0089 0.043 0.0545
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0248 0.1433 0.1502
Brugia malayi jmjC domain containing protein 0.0101 0.0503 0.0638
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0155 0.0119
Brugia malayi Latrophilin receptor protein 2 0.0041 0.0125 0.0157
Onchocerca volvulus 0.0071 0.0315 0.0467
Onchocerca volvulus 0.0039 0.011 0.0114
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0241 0.0295
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi proteasome subunit beta type 2 0.0607 0.3711 0.4722
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0055 0.0055
Brugia malayi Protein set-1 0.0078 0.0358 0.0453
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) hypothetical protein 0.0051 0.0188 0.0228
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0034 0.0082 0.0024
Schistosoma mansoni neuropeptide receptor 0.0071 0.0315 0.033
Plasmodium falciparum pyruvate kinase 0.0033 0.0073 0.009
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0133 0.0167
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0036 0.0093 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Echinococcus granulosus thioredoxin glutathione reductase 0.0091 0.0442 0.053
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0081
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.001 0.001
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0039 0.011 0.0137
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Schistosoma mansoni biogenic amine receptor 0.0071 0.0315 0.033
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0231 0.1326 0.1621
Schistosoma mansoni biogenic amine (5HT) receptor 0.0071 0.0315 0.033
Brugia malayi hypothetical protein 0.0039 0.011 0.0137
Echinococcus granulosus tm gpcr rhodopsin 0.0071 0.0315 0.0378
Echinococcus multilocularis microtubule associated protein 2 0.1337 0.8338 0.8338
Echinococcus granulosus neuropeptide FF receptor 2 0.0071 0.0315 0.0378
Onchocerca volvulus 0.004 0.0116 0.0124
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0231 0.1326 0.1621
Loa Loa (eye worm) hypothetical protein 0.0081 0.0379 0.0471
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0121 0.0152
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Mycobacterium leprae proteasome (beta subunit) PrcB 0.1261 0.7856 1
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0098 0.0485 0.0485
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0137 0.0734 0.0923
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0042 0.0129 0.0135
Plasmodium vivax apical sushi protein, putative 0.0067 0.0288 0.0365
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0042 0.0129 0.0161
Onchocerca volvulus 0.0067 0.0288 0.0421
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0031
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0121 0.0152
Echinococcus multilocularis fmrfamide receptor 0.0071 0.0315 0.0315
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Echinococcus multilocularis dnaJ subfamily B 0.0555 0.3381 0.3381
Echinococcus multilocularis Furin 1 0.0232 0.1332 0.1332
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.098 0.6073 0.7721
Plasmodium vivax proteasome subunit beta type-5, putative 0.1261 0.7856 1
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0121 0.0152
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0073 0.0323 0.0323
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0248 0.1433 0.1823
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.005 0.0061
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0039 0.011 0.011
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Onchocerca volvulus 0.0039 0.011 0.0114
Echinococcus granulosus lysosomal alpha glucosidase 0.0133 0.0705 0.0845
Toxoplasma gondii subtilisin SUB4 0.0042 0.0129 0.0142
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0981 0.6082 0.6371
Echinococcus granulosus cathepsin L cysteine proteinase 0.0043 0.0133 0.0159
Echinococcus multilocularis SAM and MBT domain containing protein 0.004 0.0116 0.0116
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0042 0.0129 0.0085
Entamoeba histolytica cysteine protease, putative 0.0043 0.0133 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0041 0.0125 0.015
Echinococcus granulosus pyruvate kinase 0.0033 0.0073 0.0087
Loa Loa (eye worm) cysteine protease 0.0043 0.0133 0.0157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0137 0.0734 0.0923
Trichomonas vaginalis esterase, putative 0.0079 0.0365 0.0462
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Schistosoma mansoni microtubule-associated protein tau 0.1337 0.8338 0.8734
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0065 0.0274 0.0287
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis c4b binding protein beta chain 0.0067 0.0288 0.0288
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.098 0.6073 0.6073
Onchocerca volvulus 0.0043 0.0133 0.0153
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0063 0.0037
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0034 0.0031
Brugia malayi AKH receptor 0.0071 0.0315 0.0399
Toxoplasma gondii peptidase, T1 family protein 0.0248 0.1433 0.1807
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0067 0.0289 0.0346
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0032 0.0066 0.0066
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Echinococcus granulosus somatostatin receptor 0.0071 0.0315 0.0378
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Toxoplasma gondii proteasome subunit alpha type, putative 0.0248 0.1433 0.1807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0071 0.0315 0.033
Mycobacterium ulcerans lipase LipD 0.0079 0.0365 0.0388
Leishmania major alpha glucosidase II subunit, putative 0.0029 0.005 0.0021
Echinococcus multilocularis nuclear receptor nhr 48 0.0065 0.0274 0.0274
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0248 0.1433 0.1823
Giardia lamblia Cyclin A 0.0032 0.0066 0.0004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0052 0.0192 0.0202
Loa Loa (eye worm) hypothetical protein 0.013 0.0688 0.0865
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0047 0.0057
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0248 0.1433 0.1807
Echinococcus multilocularis cathepsin L 0.0022 0.0002 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0155 0.0156
Echinococcus granulosus serotonin receptor 0.0071 0.0315 0.0378
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0137 0.0734 0.0923
Onchocerca volvulus Huntingtin homolog 0.0081 0.0379 0.0576
Echinococcus multilocularis cysteine protease 0.0043 0.0133 0.0133
Brugia malayi G protein-coupled receptor F59B2.13 0.0071 0.0315 0.0399
Schistosoma mansoni hypothetical protein 0.0039 0.011 0.0115
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0208 0.1179 0.1432
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0052 0.0192 0.0201
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0274 0.0274
Trypanosoma cruzi cyclin, putative 0.0051 0.0188 0.0237
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0116 0.0601 0.069
Onchocerca volvulus 0.0071 0.0315 0.0467
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0045 0.015 0.018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0137 0.0734 0.088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.1261 0.7856 1
Brugia malayi nuclear receptor NHR-88 0.0137 0.0734 0.0932
Echinococcus multilocularis lamin 0.013 0.0688 0.0688
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0607 0.3711 0.4722
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0121 0.0444
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus multilocularis neuropeptide receptor 0.0071 0.0315 0.0315
Mycobacterium leprae Possible secreted protease 0.0042 0.0129 0.0072
Onchocerca volvulus 0.0043 0.0133 0.0153
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0248 0.1433 0.1502
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Echinococcus granulosus fmrfamide receptor 0.0071 0.0315 0.0378
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0248 0.1433 0.1815
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0073 0.009
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Brugia malayi Subtilase family protein 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi G-protein coupled receptor 0.0071 0.0315 0.0399
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi orphan nuclear receptor NR2E1 0.0065 0.0274 0.0346
Brugia malayi conserved hypotetical protein 0.0065 0.0274 0.0346
Toxoplasma gondii exonuclease III APE 0.0041 0.0121 0.0132
Onchocerca volvulus Cathepsin F homolog 0.0043 0.0133 0.0153
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0093 0.0116
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.098 0.6073 0.773
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0071 0.0315 0.033
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0043 0.0133 0.0167
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0248 0.1433 0.1823
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0042 0.0129 0.0161
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0042 0.0129 0.0161
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0137 0.0734 0.0734
Echinococcus multilocularis proteasome subunit alpha type 2 0.0248 0.1433 0.1433
Brugia malayi neuropeptide F receptor 0.0071 0.0315 0.0399
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Mycobacterium tuberculosis Conserved protein 0.0079 0.0365 0.0388
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0218
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0121 0.0145
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Loa Loa (eye worm) WD40 repeat protein 0.0283 0.1657 0.21
Brugia malayi hypothetical protein 0.0081 0.0379 0.0479
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0365 0.0462
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.004 0.0116 0.0136
Onchocerca volvulus 0.0071 0.0315 0.0467
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1261 0.7856 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0101 0.0503 0.0503
Echinococcus granulosus proteasome subunit beta t family 0.0248 0.1433 0.1719
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0071 0.0315 0.0399
Onchocerca volvulus Notchless protein homolog 0.0248 0.1433 0.239
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.1261 0.7856 0.8229
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0073 0.0323 0.04
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Brugia malayi RNA recognition motif domain containing protein 0.0191 0.1076 0.1368
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0116 0.0145
Onchocerca volvulus 0.006 0.0241 0.034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0639 0.067
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.019 0.1066 0.1355
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) PAS-3 protein 0.0248 0.1433 0.1815
Mycobacterium ulcerans 3-dehydroquinate dehydratase 0.1162 0.7227 0.9194
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0068 0.0296 0.0296
Giardia lamblia Proteasome subunit beta type 1 0.098 0.6073 0.7712
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0051 0.0188 0.0197
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus granulosus Proteasome subunit alpha beta 0.0248 0.1433 0.1719
Echinococcus multilocularis integrin alpha ps 0.0066 0.0284 0.0284
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) proprotein convertase 2 0.0232 0.1332 0.1685
Schistosoma mansoni neuropeptide receptor 0.0575 0.351 0.3677
Plasmodium falciparum thioredoxin reductase 0.0091 0.044 0.0558
Brugia malayi G protein-coupled receptor 0.0071 0.0315 0.0399
Brugia malayi beta-lactamase family protein 0.0079 0.0365 0.0462
Echinococcus granulosus neuropeptide receptor A26 0.036 0.2142 0.2569
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0065 0.0274 0.0346
Trichomonas vaginalis cyclin D, putative 0.0032 0.0066 0.0082
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0133 0.0705 0.0886
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.1433 0.1815
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0034 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.006 0.0246 0.0302
Entamoeba histolytica cyclin, putative 0.0051 0.0188 0.0237
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0137 0.0734 0.088
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0248 0.1433 0.1433
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0248 0.1433 0.1719
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Leishmania major proteasome alpha 7 subunit, putative 0.0248 0.1433 0.179
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0071 0.0315 0.0315
Giardia lamblia 20S proteasome alpha subunit 3 0.0248 0.1433 0.1759
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0042 0.0129 0.0072
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0274 0.0328
Onchocerca volvulus 0.0067 0.0288 0.0421
Onchocerca volvulus 0.0039 0.011 0.0114
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0137 0.0734 0.0932
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Plasmodium vivax thrombospondin-related anonymous protein 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0034 0.004
Leishmania major proteasome alpha 2 subunit, putative 0.0248 0.1433 0.179
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0155 0.0119
Toxoplasma gondii cathepsin CPL 0.0043 0.0133 0.0148
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0043 0.0133 0.0133
Toxoplasma gondii proteasome subunit alpha1, putative 0.0248 0.1433 0.1807
Giardia lamblia 20S proteasome alpha subunit 5 0.0248 0.1433 0.1759
Echinococcus granulosus neuropeptides capa receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis neuropeptide Y receptor 0.0071 0.0315 0.0315
Echinococcus granulosus collagen alpha 1VII chain 0.0039 0.011 0.0132
Echinococcus granulosus pyruvate kinase 0.0033 0.0073 0.0087
Brugia malayi Melatonin receptor type 1A 0.0071 0.0315 0.0399
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0036 0.0093 0.0096
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0248 0.1433 0.1823
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Entamoeba histolytica hypothetical protein 0.0039 0.011 0.0137
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0245 0.0234
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0112 0.0574 0.0728
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0052 0.0192 0.0165
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0042 0.0129 0.0161
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Schistosoma mansoni hypothetical protein 0.0039 0.011 0.0115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Echinococcus granulosus dnaJ subfamily B 0.0555 0.3381 0.4055
Echinococcus granulosus integrin alpha 3 0.0114 0.0583 0.07
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0607 0.3711 0.4722
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus granulosus cathepsin L cysteine protease 0.0022 0.0002 0.0002
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1261 0.7856 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0091 0.0439 0.0557
Echinococcus granulosus cyclin b3 0.0032 0.0066 0.0079
Loa Loa (eye worm) histone methyltransferase 0.0025 0.0023 0.0018
Schistosoma mansoni site-1 peptidase (S08 family) 0.0042 0.0129 0.0135
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0121 0.0152
Brugia malayi 20S proteasome alpha5 subunit 0.0248 0.1433 0.1823
Echinococcus granulosus proteasome subunit alpha type 2 0.0248 0.1433 0.1719
Onchocerca volvulus 0.0071 0.0315 0.0467
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0071 0.0315 0.0315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus granulosus tachykinin peptides receptor 99D 0.0071 0.0315 0.0378
Leishmania major cysteine peptidase A (CPA) 0.0043 0.0133 0.0127
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0065 0.0274 0.0337
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.1348 0.1706
Toxoplasma gondii subtilisin SUB1 0.0042 0.0129 0.0142
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0274 0.0346
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0315
Schistosoma mansoni histone-lysine n-methyltransferase seto7 0.0078 0.0358 0.0375
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0365 0.0388
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0091 0.0439 0.068
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.004 0.0116 0.0105
Schistosoma mansoni alpha-glucosidase 0.0114 0.0587 0.0615
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0067 0.0288 0.0421
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0071 0.0315 0.0315
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0248 0.1433 0.1815
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0365 0.0388
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Loa Loa (eye worm) TAR-binding protein 0.0191 0.1076 0.136
Trichomonas vaginalis cyclins, putative 0.0032 0.0066 0.0082
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0248 0.1433 0.1502
Chlamydia trachomatis pyruvate kinase 0.0033 0.0073 0.0637
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0034 0.004
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0607 0.3711 0.4722
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0137 0.0734 0.088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Treponema pallidum hypothetical protein 0.0039 0.011 0.0357
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0199
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0176
Echinococcus granulosus citrate lyase subunit beta protein 0.0048 0.0167 0.0201
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0073 0.009
Echinococcus granulosus proteasome subunit alpha type 6 0.0248 0.1433 0.1719
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Brugia malayi Serotonin receptor 0.0071 0.0315 0.0399
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0075
Loa Loa (eye worm) hypothetical protein 0.0131 0.0692 0.087
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.098 0.6073 0.6361
Loa Loa (eye worm) hypothetical protein 0.0385 0.2302 0.2922
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0137 0.0734 0.088
Brugia malayi Pre-SET motif family protein 0.0832 0.5133 0.6534
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0275
Loa Loa (eye worm) proteasome subunit beta type 3 0.0248 0.1433 0.1815
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Trypanosoma cruzi cysteine peptidase, putative 0.0043 0.0133 0.0167
Echinococcus multilocularis serotonin receptor 0.0071 0.0315 0.0315
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0034 0.0034
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0274 0.0287
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0596 0.3642 0.4635
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.004 0.0116 0.0121
Schistosoma mansoni cpg binding protein 0.006 0.0241 0.0253
Entamoeba histolytica elongation factor-2 kinase, putative 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Toxoplasma gondii proteasome subunit beta type 1, putative 0.098 0.6073 0.7725
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0034 0.0034
Schistosoma mansoni opsin-like receptor 0.0071 0.0315 0.033
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0066 0.0082
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0157
Onchocerca volvulus 0.0137 0.0734 0.1187
Echinococcus granulosus proteasome prosome macropain 0.1261 0.7856 0.9421
Leishmania major subtilisin-like serine peptidase 0.0042 0.0129 0.0122
Leishmania major proteasome beta 3 subunit, putative 0.0248 0.1433 0.179
Onchocerca volvulus 0.0071 0.0315 0.0467
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.1131
Toxoplasma gondii subtilisin SUB10 0.0042 0.0129 0.0142
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0063 0.0078
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Loa Loa (eye worm) beta-lactamase 0.0079 0.0365 0.0454
Schistosoma mansoni hypothetical protein 0.0032 0.0065 0.0068
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Echinococcus granulosus peptide allatostatin:somatostatin 0.0071 0.0315 0.0378
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0045 0.015 0.0189
Brugia malayi MAP kinase sur-1 0.0036 0.0093 0.0116
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0039 0.011 0.0137
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0043 0.0133 0.0167
Onchocerca volvulus 0.0071 0.0315 0.0467
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0248 0.1433 0.1823
Echinococcus granulosus polycomb protein SCMH1 0.004 0.0116 0.0139
Leishmania major cathepsin L-like protease 0.0162 0.0891 0.1096
Echinococcus multilocularis ubiquitin specific protease 41 0.0052 0.0192 0.0192
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus multilocularis G-protein coupled receptor, putative 0.0071 0.0315 0.0315
Onchocerca volvulus 0.0946 0.5858 1
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0248 0.1433 0.1759
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.019 0.1066 0.1355
Onchocerca volvulus 0.0045 0.0148 0.0179
Loa Loa (eye worm) nuclear hormone receptor 0.0065 0.0274 0.0337
Plasmodium falciparum apical sushi protein 0.0067 0.0288 0.0365
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0248 0.1433 0.1502
Plasmodium vivax vivapain-2 0.0043 0.0133 0.0167
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Schistosoma mansoni growth hormone secretagogue receptor 0.0071 0.0315 0.033
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0052 0.0192 0.0242
Echinococcus granulosus beta-adrenergic receptor kinase 0.0109 0.0557 0.0668
Brugia malayi Cyclin, N-terminal domain containing protein 0.0051 0.0188 0.0237
Trichomonas vaginalis cyclin D, putative 0.0032 0.0066 0.0082
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0071 0.0315 0.0467
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0036 0.0093 0.0116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0071 0.0315 0.039
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0041 0.0125 0.015
Schistosoma mansoni hypothetical protein 0.0113 0.0581 0.0609
Toxoplasma gondii subtilisin SUB2 0.0042 0.0129 0.0142
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0365 0.0462
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0248 0.1433 0.1823
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0365 0.0388
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0121 0.0152
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Echinococcus multilocularis tumor protein p63 0.0213 0.1213 0.1213
Echinococcus multilocularis pyruvate kinase 0.0033 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0052 0.0192 0.0232
Brugia malayi Probable ClpP-like protease 0.0056 0.0218 0.0275
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0248 0.1433 0.1823
Leishmania major proteasome beta 5 subunit, putative 0.1261 0.7856 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0137 0.0734 0.0769
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0708 0.0742
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0274 0.0328
Echinococcus multilocularis polycomb protein SCMH1 0.004 0.0116 0.0116
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0071 0.0315 0.033
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0137 0.0734 0.0932
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0365 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Brugia malayi nuclear receptor NHR-67 0.0065 0.0274 0.0346
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0167 0.0134
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0052 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0031
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0039 0.011 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0137 0.0734 0.0932
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0137 0.0734 0.088
Echinococcus granulosus neutral alpha glucosidase AB 0.0029 0.005 0.006
Onchocerca volvulus 0.0122 0.0639 0.1024
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni biogenic amine receptor 0.0071 0.0315 0.033
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0137 0.0734 0.0769
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0121 0.0075
Plasmodium vivax subtilisin-like protease 1 0.0042 0.0129 0.0161
Onchocerca volvulus 0.0042 0.0129 0.0146
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Brugia malayi mbt repeat family protein 0.004 0.0116 0.0145
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Echinococcus granulosus cathepsin l1 0.0028 0.0044 0.0052
Loa Loa (eye worm) hypothetical protein 0.0046 0.0155 0.0186
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0121 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0137 0.0734 0.0932
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Onchocerca volvulus 0.0067 0.0288 0.0421
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni ap endonuclease 0.0041 0.0121 0.0127
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0037 0.0096 0.0029
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.011 0.0137
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0607 0.3711 0.4712
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Echinococcus granulosus 7tm_1 domain containing protein 0.0071 0.0315 0.0378
Schistosoma mansoni neuropeptide receptor 0.0071 0.0315 0.033
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0043 0.0133 0.0133
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Loa Loa (eye worm) hypothetical protein 0.0082 0.0381 0.0474
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0581 0.0581
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Treponema pallidum 76K protein 0.0039 0.011 0.0357
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.004 0.0116 0.0145
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0042 0.0129 0.0085
Schistosoma mansoni hypothetical protein 0.0091 0.0439 0.046
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0037
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0248 0.1433 0.1823
Toxoplasma gondii histone lysine methyltransferase SET8 0.0078 0.0358 0.0435
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0248 0.1433 0.1759
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0248 0.1433 0.1807
Loa Loa (eye worm) hypothetical protein 0.015 0.0813 0.1025
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) TYRA-2 protein 0.0071 0.0315 0.039
Brugia malayi Tachykinin-like peptides receptor 99D 0.0071 0.0315 0.0399
Loa Loa (eye worm) hypothetical protein 0.004 0.0116 0.0135
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium tuberculosis Probable dehydrogenase 0.0208 0.1179 0.1432
Echinococcus granulosus ecdysone induced protein 78C 0.0137 0.0734 0.088
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0034 0.004
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0167 0.021
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Trypanosoma brucei proteasome subunit beta type-5, putative 0.1261 0.7856 1
Echinococcus granulosus g protein coupled receptor 0.0071 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis orexin receptor type 2 0.0071 0.0315 0.0315
Echinococcus granulosus intermediate filament protein 0.013 0.0688 0.0825
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0248 0.1433 0.1759
Giardia lamblia High cysteine membrane protein Group 2 0.0365 0.2174 0.2709
Echinococcus multilocularis neuroendocrine convertase 2 0.0617 0.3771 0.3771
Echinococcus granulosus dro:myosuppressin receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0365 0.0462
Echinococcus granulosus g-protein coupled receptor 0.0071 0.0315 0.0378
Giardia lamblia 20S proteasome alpha subunit 4 0.0248 0.1433 0.1759
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0137 0.0734 0.0932
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0067 0.0288 0.0356
Onchocerca volvulus Huntingtin homolog 0.0081 0.0379 0.0576
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.004 0.0116 0.0145
Brugia malayi Serotonin receptor 0.0071 0.0315 0.0399
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0039 0.011 0.0137
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Brugia malayi larval opioid receptor 0.0071 0.0315 0.0399
Echinococcus multilocularis neutral alpha glucosidase AB 0.0029 0.005 0.005
Schistosoma mansoni biogenic amine (5HT) receptor 0.0071 0.0315 0.033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Echinococcus granulosus microtubule associated protein 2 0.1337 0.8338 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.005 0.0061
Onchocerca volvulus 0.0071 0.0315 0.0467
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0365 0.0462
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0039 0.011 0.011
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0248 0.1433 0.1502
Toxoplasma gondii heat shock protein hslv, putative 0.0248 0.1433 0.1807
Schistosoma mansoni pyruvate kinase 0.0033 0.0073 0.0076
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Mycobacterium ulcerans hypothetical protein 0.0108 0.0551 0.0626
Echinococcus granulosus lamin dm0 0.013 0.0688 0.0825
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0029 0.005 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi hypothetical protein 0.0106 0.0533 0.0677
Schistosoma mansoni c4b-binding protein beta chain 0.0067 0.0288 0.0302
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0071 0.0315 0.0467
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0131 0.0692 0.0879
Toxoplasma gondii subtilisin SUB8 0.0042 0.0129 0.0142
Giardia lamblia Proteasome subunit beta type 2 0.0607 0.3711 0.4681
Echinococcus multilocularis proteasome subunit beta type 7 0.0248 0.1433 0.1433
Loa Loa (eye worm) calpain family protein 1 0.0064 0.0268 0.033
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.098 0.6073 0.773
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0248 0.1433 0.1502
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0248 0.1433 0.1823
Echinococcus granulosus leukotriene A 4 hydrolase 0.023 0.1321 0.1584
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0052 0.0192 0.0242
Toxoplasma gondii proteasome subunit beta type, putative 0.1261 0.7856 1
Onchocerca volvulus 0.0065 0.0274 0.0396
Echinococcus multilocularis pyruvate kinase 0.0026 0.0029 0.0029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0071 0.0315 0.033
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0274 0.0346
Brugia malayi nuclear hormone receptor 0.0065 0.0274 0.0346
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0137 0.0734 0.0769
Plasmodium falciparum glutathione reductase 0.0032 0.0063 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Mycobacterium ulcerans hypothetical protein 0.0048 0.0167 0.0134
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0245 0.0245
Trypanosoma cruzi subtilisin peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0078 0.0358 0.0444
Echinococcus granulosus cysteine protease 0.0022 0.0002 0.0002
Onchocerca volvulus 0.0043 0.0133 0.0153
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0036 0.0093 0.0116
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Toxoplasma gondii proteasome beta subunit 0.0248 0.1433 0.1807
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0114 0.0588 0.0705
Loa Loa (eye worm) thioredoxin reductase 0.0091 0.044 0.0549
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trichomonas vaginalis maltase-glucoamylase, putative 0.0029 0.005 0.0061
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0071 0.0315 0.0315
Schistosoma mansoni adenoreceptor 0.0071 0.0315 0.033
Echinococcus multilocularis FTZ F1 alpha 0.0137 0.0734 0.0734
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0039 0.011 0.0128
Brugia malayi Zona pellucida-like domain containing protein 0.0039 0.011 0.0137
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Loa Loa (eye worm) hypothetical protein 0.0446 0.2688 0.3413
Schistosoma mansoni alpha glucosidase 0.0029 0.005 0.0052
Loa Loa (eye worm) hypothetical protein 0.0122 0.0639 0.0803
Mycobacterium ulcerans proteasome PrcB 0.1261 0.7856 1
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0596 0.3642 0.3642
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0206 0.1168 0.1485
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0063 0.0078
Loa Loa (eye worm) hypothetical protein 0.0128 0.0673 0.0845
Schistosoma mansoni cpg binding protein 0.0063 0.0263 0.0275
Loa Loa (eye worm) hypothetical protein 0.0051 0.0188 0.0228
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0248 0.1433 0.1502
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0131 0.0692 0.087
Loa Loa (eye worm) glutathione reductase 0.0091 0.044 0.0549
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi hypothetical protein 0.0446 0.2688 0.342
Loa Loa (eye worm) leukotriene A4 hydrolase 0.023 0.1321 0.1672
Schistosoma mansoni cyclin B3 0.0032 0.0066 0.0069
Echinococcus multilocularis neuropeptides capa receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0165 0.091 0.091
Leishmania major proteasome beta 2 subunit, putative 0.0248 0.1433 0.179
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0167 0.021
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0137 0.0734 0.088
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0248 0.1433 0.1815
Onchocerca volvulus 0.0067 0.0288 0.0421
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0137 0.0734 0.0932
Echinococcus multilocularis lysine specific demethylase 5A 0.0101 0.0503 0.0503
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.005 0.0061
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0042 0.0129 0.0085
Brugia malayi beta-lactamase 0.0079 0.0365 0.0462
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0121 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi nuclear receptor NHR-88 0.0065 0.0274 0.0346
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0734 0.0769
Echinococcus multilocularis cyclin b3 0.0032 0.0066 0.0066
Onchocerca volvulus 0.0079 0.0365 0.0553
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0122 0.0639 0.067
Echinococcus multilocularis neuropeptide receptor 0.0575 0.351 0.351
Brugia malayi Integrin alpha pat-2 precursor 0.0148 0.0803 0.102
Plasmodium falciparum glutathione reductase 0.0091 0.044 0.0558
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.1348 0.1706
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0245 0.0257
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0063 0.0078
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0065 0.0274 0.0274
Brugia malayi Proteasome subunit alpha type 7-1 0.0248 0.1433 0.1823
Schistosoma mansoni furin-1 (S08 family) 0.0427 0.2568 0.269
Leishmania major pyruvate kinase 0.0033 0.0073 0.005
Loa Loa (eye worm) fibroinase 0.0043 0.0133 0.0157
Schistosoma mansoni ap endonuclease 0.0041 0.0121 0.0127
Echinococcus multilocularis thyroid hormone receptor alpha 0.0137 0.0734 0.0734
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0506 0.3071 0.3861
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0063 0.0078
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Echinococcus granulosus neuropeptide receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0155 0.0106
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0032 0.0066 0.0079
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0248 0.1433 0.1433
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis transcription factor Dp 1 0.0023 0.0009 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0044 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0417 0.2505 0.3187
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Brugia malayi Intermediate filament tail domain containing protein 0.013 0.0688 0.0873
Brugia malayi glutathione reductase 0.0091 0.044 0.0558
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0365 0.0462
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0199
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0071 0.0315 0.033
Giardia lamblia Kinase, CMGC MAPK 0.0036 0.0093 0.0038
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus granulosus 7TM GPCR rhodopsin 0.0071 0.0315 0.0378
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0165 0.091 0.1092
Echinococcus multilocularis cpg binding protein 0.0063 0.0263 0.0263
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Plasmodium falciparum thrombospondin-related anonymous protein 0.0039 0.011 0.0137
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0073 0.0323 0.0387
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0296 0.031
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0365 0.0388
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0248 0.1433 0.1823
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0623 0.0772
Schistosoma mansoni alpha-1 adrenergic receptor 0.0071 0.0315 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.003 0.0052 0.0054
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0481 0.061
Echinococcus granulosus neuropeptide Y receptor 0.0071 0.0315 0.0378
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0071 0.0315 0.0378
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0071 0.0315 0.039
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0206 0.1168 0.1485
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.019 0.1066 0.1355
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.1183
Brugia malayi jmjC domain containing protein 0.0104 0.0525 0.0665
Echinococcus multilocularis GPCR, family 2 0.0041 0.0125 0.0125
Brugia malayi proprotein convertase 2 0.0617 0.3771 0.4799
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0039 0.011 0.0137
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0063 0.0261 0.0313
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium ulcerans hypothetical protein 0.0048 0.0167 0.0134
Echinococcus multilocularis g protein coupled receptor 0.0071 0.0315 0.0315
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0248 0.1433 0.1502
Schistosoma mansoni jumonji domain containing protein 0.0101 0.0503 0.0527
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0248 0.1433 0.1823
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Plasmodium vivax subtilisin-like serine protease, putative 0.0042 0.0129 0.0161
Echinococcus multilocularis neuropeptide Y receptor 0.0071 0.0315 0.0315
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0248 0.1433 0.1433
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0137 0.0734 0.0769
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Schistosoma mansoni nuclear receptor 0.0065 0.0274 0.0287
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0365 0.0376
Echinococcus granulosus Proteasome subunit alpha type 7 0.0248 0.1433 0.1719
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1528 0.9546 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0155 0.0119
Trypanosoma brucei proteasome alpha 7 subunit 0.0248 0.1433 0.1823
Schistosoma mansoni neuropeptide F-like receptor 0.0071 0.0315 0.033
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0192 0.0242
Plasmodium falciparum proteasome subunit beta type-5 0.1261 0.7856 1
Toxoplasma gondii subtilisin SUB7 0.0042 0.0129 0.0142
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0248 0.1433 1
Schistosoma mansoni retinoic acid receptor RXR 0.0137 0.0734 0.0769
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0248 0.1433 0.1823
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Brugia malayi Cathepsin L-like cysteine proteinase 0.0028 0.0044 0.0053
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0155 0.0195
Echinococcus granulosus survival motor neuron protein 1 0.0446 0.2688 0.3223
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0071 0.0315 0.033
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0073 0.0071
Toxoplasma gondii rhoptry neck protein RON9 0.0067 0.0288 0.0346
Trypanosoma cruzi hypothetical protein, conserved 0.0417 0.2505 0.3187
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0065 0.0274 0.0274
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0734 0.0769
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0071 0.0315 0.033
Brugia malayi follicle stimulating hormone receptor 0.0547 0.3328 0.4235
Loa Loa (eye worm) integrin alpha pat-2 0.0229 0.1312 0.166
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0832 0.5133 0.6531
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.004 0.0116 0.0121
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0034 0.0035
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0274 0.0396
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0091 0.044 0.0484
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0044 0.0053
Loa Loa (eye worm) DR-78 0.0065 0.0274 0.0337
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0056 0.0218 0.0186
Echinococcus multilocularis g protein coupled receptor 0.0071 0.0315 0.0315
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Loa Loa (eye worm) hypothetical protein 0.0981 0.6082 0.7739
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0048 0.0167 0.0134
Schistosoma mansoni cathepsin F (C01 family) 0.0043 0.0133 0.0139
Plasmodium vivax proteasome subunit beta type-1, putative 0.098 0.6073 0.773
Plasmodium vivax subtilisin-like protease 2, putative 0.0042 0.0129 0.0161
Echinococcus multilocularis pyruvate kinase 0.0033 0.0073 0.0073
Echinococcus multilocularis somatostatin receptor 0.0071 0.0315 0.0315
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0137 0.0734 0.0769
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0048 0.0167 0.0134
Schistosoma mansoni site-1 peptidase (S08 family) 0.0042 0.0129 0.0135
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0596 0.3642 0.4369
Echinococcus granulosus Furin 1 0.0232 0.1332 0.1597
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0137 0.0734 0.0769
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0063 0.0078
Echinococcus multilocularis lamin dm0 0.013 0.0688 0.0688
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0296 0.031
Toxoplasma gondii hypothetical protein 0.0033 0.0074 0.0072
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0039 0.011 0.0114
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Giardia lamblia 20S proteasome alpha subunit 2 0.0248 0.1433 0.1759
Trypanosoma brucei mitotic cyclin 6 0.0051 0.0188 0.0237
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0071 0.0315 0.0399
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0248 0.1433 0.1823
Echinococcus granulosus protein will die slowly 0.0283 0.1657 0.1987
Echinococcus granulosus peptidase Clp S14 family 0.0037 0.0096 0.0115
Brugia malayi celfurPC protein 0.0791 0.4879 0.621
Loa Loa (eye worm) cyclin domain-containing protein 0.0032 0.0066 0.0073
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0023 0.0028
Trypanosoma cruzi cyclin, putative 0.0051 0.0188 0.0237
Schistosoma mansoni cathepsin F (C01 family) 0.0043 0.0133 0.0139
Trypanosoma brucei trypanothione reductase 0.0091 0.044 0.0558
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni myelin transcription factor 1 myt1 0.0045 0.015 0.0158
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0607 0.3711 0.3887
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Echinococcus granulosus G protein coupled receptor kinase 1 0.0098 0.0485 0.0582
Brugia malayi CXXC zinc finger family protein 0.006 0.0241 0.0305
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0036 0.0093 0.0076
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Onchocerca volvulus 0.0067 0.0288 0.0421
Echinococcus multilocularis serotonin receptor 0.0071 0.0315 0.0315
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1261 0.7856 1
Echinococcus multilocularis allatostatin A receptor 0.0071 0.0315 0.0315
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0137 0.0734 0.088
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0071 0.0315 0.0399
Mycobacterium tuberculosis 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 0.1162 0.7227 0.9194
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0155 0.0119
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0365 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Echinococcus granulosus neuropeptide Y receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Brugia malayi Calcitonin receptor-like protein seb-1 0.0131 0.0692 0.0879
Loa Loa (eye worm) proteasome subunit beta type 2 0.0607 0.3711 0.4717
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0248 0.1433 0.1807
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Onchocerca volvulus 0.0051 0.0188 0.0248
Trypanosoma cruzi cysteine peptidase, putative 0.0162 0.0891 0.1132
Brugia malayi Proteasome A-type and B-type family protein 0.1261 0.7856 1
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0042 0.0129 0.0161
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.005 0.0061
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0023 0.0024
Brugia malayi Cathepsin L-like precursor 0.0028 0.0044 0.0053
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0045 0.015 0.018
Echinococcus multilocularis proteasome (prosome, macropain) 0.1261 0.7856 0.7856
Brugia malayi cathepsin L-like precursor 0.0028 0.0044 0.0053
Loa Loa (eye worm) subtilase 0.0042 0.0129 0.0152
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0042 0.0129 0.0135
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0137 0.0734 0.0923
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0073 0.009
Onchocerca volvulus Cathepsin L homolog 0.0043 0.0133 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0116 0.0121
Echinococcus granulosus sex peptide receptor 0.0071 0.0315 0.0378
Schistosoma mansoni lamin 0.013 0.0688 0.072
Loa Loa (eye worm) hypothetical protein 0.0064 0.0268 0.033
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni hypothetical protein 0.0555 0.3381 0.3542
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0137 0.0734 0.0932
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0378
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis cyclin A, putative 0.0051 0.0188 0.0237
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0052 0.0192 0.023
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0042 0.0129 0.0129
Brugia malayi Dopamine receptor protein 1 0.0071 0.0315 0.0399
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.0639 0.0794
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0029 0.0047 0.0057
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0037 0.0096 0.0042
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0365 0.0454
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0052 0.0192 0.0242
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0248 0.1433 0.179
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0116 0.0145
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0068 0.0296 0.0366
Schistosoma mansoni cyclins 0.0032 0.0066 0.0069
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.098 0.6073 0.773
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Echinococcus granulosus integrin alpha ps 0.0032 0.0065 0.0078
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0073 0.009
Brugia malayi Cyclin, N-terminal domain containing protein 0.0032 0.0066 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0137 0.0734 0.0923
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Brugia malayi nuclear hormone receptor family member nhr-6 0.0065 0.0274 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0034 0.0035
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0121 0.0142
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium leprae Probable lipase LipE 0.0079 0.0365 0.0376
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.1261 0.7856 1
Mycobacterium ulcerans hypothetical protein 0.0079 0.0365 0.0388
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.004 0.0116 0.0116
Toxoplasma gondii microneme protein MIC2 0.0039 0.011 0.0118
Trichomonas vaginalis sucrase-isomaltase, putative 0.0029 0.005 0.0061
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0248 0.1433 0.1823
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0081 0.0379 0.0471
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0315
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Toxoplasma gondii subtilisin SUB11 0.0042 0.0129 0.0142
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0071 0.0315 0.0399
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0274 0.0287
Echinococcus granulosus tar DNA binding protein 0.0191 0.1076 0.1291
Schistosoma mansoni cpg binding protein 0.0063 0.0263 0.0275
Echinococcus granulosus mitogen activated protein kinase 3 0.0036 0.0093 0.0111
Brugia malayi G-protein coupled receptor 0.0071 0.0315 0.0399
Plasmodium vivax proteasome subunit beta type-3, putative 0.0248 0.1433 0.1823
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.0639 0.0639
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0071 0.0315 0.039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0044 0.0053
Echinococcus granulosus histone lysine n methyltransferase setd8 0.0078 0.0358 0.0429
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0109 0.0557 0.0698
Loa Loa (eye worm) CUTiclin family member 0.0039 0.011 0.0128
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0034 0.004
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0037
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0121 0.0112
Echinococcus granulosus transcription factor Dp 1 0.0023 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Echinococcus multilocularis G protein coupled receptor 139 0.0575 0.351 0.351
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0116 0.0601 0.069
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Trypanosoma cruzi CYC2-like cyclin, putative 0.0051 0.0188 0.0237
Onchocerca volvulus 0.0067 0.0288 0.0421
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0155 0.0119
Brugia malayi ecdysteroid receptor 0.0137 0.0734 0.0932
Brugia malayi cytoplasmic intermediate filament protein 0.007 0.0305 0.0386
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0365 0.0462
Leishmania major proteasome alpha 1 subunit, putative 0.0248 0.1433 0.179
Echinococcus granulosus histone lysine methyltransferase setb 0.0122 0.0639 0.0767
Leishmania major proteasome beta 7 subunit, putative 0.0248 0.1433 0.179
Echinococcus multilocularis lysosomal alpha glucosidase 0.0133 0.0705 0.0705
Mycobacterium ulcerans hypothetical protein 0.0046 0.0155 0.0119
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0047 0.0057
Schistosoma mansoni nuclear hormone receptor 0.0137 0.0734 0.0769
Trypanosoma cruzi cyclin 6, putative 0.0051 0.0188 0.0237
Schistosoma mansoni cyclin B 0.0051 0.0188 0.0197
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0034 0.004
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0248 0.1433 0.1823
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0034 0.004
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0248 0.1433 0.1719
Echinococcus multilocularis calpain family protein 1, d 0.0045 0.0148 0.0148
Loa Loa (eye worm) ctsf protein 0.0043 0.0133 0.0157
Mycobacterium tuberculosis Conserved protein 0.0079 0.0365 0.0388
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis protein will die slowly 0.0283 0.1657 0.1657
Schistosoma mansoni neuropeptide F-like receptor 0.0071 0.0315 0.033
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0192 0.0242
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0365 0.0388
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0365 0.0462
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0137 0.0734 0.0932
Echinococcus granulosus orexin receptor type 2 0.0071 0.0315 0.0378
Schistosoma mansoni hypothetical protein 0.0283 0.1657 0.1735
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Echinococcus granulosus proteasome prosome macropain subunit beta 0.098 0.6073 0.7283
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0042 0.0129 0.0085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0065 0.0274 0.0328
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0248 0.1433 0.1807
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0137 0.0734 0.0734
Toxoplasma gondii proteasome subunit 0.0248 0.1433 0.1807
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0274 0.0396
Brugia malayi Proteasome subunit alpha type 1 0.0248 0.1433 0.1823
Schistosoma mansoni myosin xvIII 0.0071 0.0315 0.033
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0323 0.0409
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Loa Loa (eye worm) MBCTL1 0.0045 0.015 0.018
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0073 0.0323 0.0338
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0133 0.0167
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.005
Schistosoma mansoni hypothetical protein 0.0452 0.273 0.286
Brugia malayi tailless protein 0.0065 0.0274 0.0346
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.0133 0.0157
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0248 0.1433 0.1433
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis cyclin B3, putative 0.0032 0.0066 0.0082
Echinococcus multilocularis geminin 0.0452 0.273 0.273
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0155 0.0156
Brugia malayi Zona pellucida-like domain containing protein 0.0039 0.011 0.0137
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0248 0.1433 0.1823
Schistosoma mansoni coup transcription factor 0.0137 0.0734 0.0769
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0081
Echinococcus multilocularis neuropeptide s receptor 0.036 0.2142 0.2142
Onchocerca volvulus 0.0071 0.0315 0.0467
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.007 0.0305 0.0377
Toxoplasma gondii rhoptry neck protein RON1 0.0067 0.0288 0.0346
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0155 0.0195
Schistosoma mansoni histamine h1 receptor 0.0071 0.0315 0.033
Leishmania major cathepsin L-like protease 0.0162 0.0891 0.1096
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis survival motor neuron protein 1 0.0446 0.2688 0.2688
Toxoplasma gondii subtilisin SUB12 0.0042 0.0129 0.0142
Schistosoma mansoni hypothetical protein 0.025 0.145 0.1519
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0365 0.0462
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0043 0.0133 0.0167
Onchocerca volvulus 0.0039 0.011 0.0114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0063 0.0261 0.0261
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0031 0.0061 0.0029
Schistosoma mansoni pyruvate kinase 0.0033 0.0073 0.0076
Brugia malayi Sushi domain 0.0067 0.0288 0.0365
Plasmodium falciparum proteasome subunit beta type-4 0.0248 0.1433 0.1823
Brugia malayi mbt repeat family protein 0.004 0.0116 0.0145
Echinococcus multilocularis calpain A 0.0067 0.0289 0.0289
Brugia malayi steroid hormone receptor 0.0137 0.0734 0.0932
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0155 0.0119
Echinococcus multilocularis histone lysine n methyltransferase setd8 0.0078 0.0358 0.0358
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0063
Mycobacterium tuberculosis Conserved protein 0.0048 0.0167 0.0134
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0068 0.0296 0.0375
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0056 0.0218 0.0275
Schistosoma mansoni nuclear receptor nhr-48 0.0065 0.0274 0.0287
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0082 0.0024
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0155 0.0195
Entamoeba histolytica proteasome subunit beta type 1, putative 0.098 0.6073 0.773
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Onchocerca volvulus 0.013 0.0688 0.1108
Echinococcus multilocularis leukotriene A 4 hydrolase 0.023 0.1321 0.1321
Echinococcus granulosus proteasome subunit beta type 6 0.0248 0.1433 0.1719
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis cathepsin L cysteine protease 0.0043 0.0133 0.0133
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0274 0.0274
Brugia malayi putative neuropeptide receptor NPR1 0.0071 0.0315 0.0399
Plasmodium falciparum subtilisin-like protease 2 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0035 0.0082 0.0093
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0034 0.0082 0.12
Onchocerca volvulus 0.0065 0.0274 0.0396
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0065
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Plasmodium vivax proteasome subunit beta type-7, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis proteasome subunit alpha type 6 0.0248 0.1433 0.1433
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.1433 0.1815
Echinococcus granulosus G protein coupled receptor 139 0.0071 0.0315 0.0378
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0071 0.0315 0.039
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0052 0.0192 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Brugia malayi hypothetical protein 0.015 0.0813 0.1033
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0067 0.0289 0.0303
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis cyclin B, putative 0.0032 0.0066 0.0082
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0063 0.0078
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0042 0.0129 0.0085
Echinococcus multilocularis musashi 0.013 0.0688 0.0688
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0042 0.0129 0.0154
Toxoplasma gondii subtilisin SUB5 0.0042 0.0129 0.0142
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Plasmodium vivax hypothetical protein, conserved 0.0039 0.011 0.0137
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0121 0.0121
Giardia lamblia Fructose-bisphosphate aldolase 0.0238 0.1373 0.1681
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Brugia malayi hypothetical protein 0.0073 0.0323 0.0409
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0039 0.011 0.0137
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0167 0.0134
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0137 0.0734 0.0932
Brugia malayi nuclear receptor RXR 0.0073 0.0323 0.0409
Plasmodium falciparum thioredoxin reductase 0.0032 0.0063 0.0078
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0248 0.1433 0.1823
Plasmodium falciparum subtilisin-like protease 1 0.0042 0.0129 0.0161
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0034 0.0035
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0365 0.0365
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0071 0.0315 0.033
Onchocerca volvulus 0.0067 0.0288 0.0421
Onchocerca volvulus 0.0043 0.0133 0.0153
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0155 0.0119
Trypanosoma brucei proteasome beta 7 subunit 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0078
Brugia malayi endoprotease bli-4 precursor 0.0981 0.6082 0.7741
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0245 0.0234
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Giardia lamblia Pyruvate kinase 0.0033 0.0073 0.0013
Loa Loa (eye worm) hypothetical protein 0.0046 0.0155 0.0186
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0248 0.1433 0.1823
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0022 0.0002 0.0002
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.023 0.1321 0.1384
Echinococcus multilocularis tar DNA binding protein 0.0191 0.1076 0.1076
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0064 0.0268 0.0281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0248 0.1433 0.1823
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0121 0.0424
Echinococcus granulosus geminin 0.0452 0.273 0.3274
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0208 0.1179 0.1432
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0067 0.0289 0.0303
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0248 0.1433 0.1433
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0581 0.0697
Onchocerca volvulus Protein ultraspiracle homolog 0.0137 0.0734 0.1187
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Schistosoma mansoni zinc finger protein 0.0065 0.0274 0.0287
Plasmodium vivax proteasome subunit beta type-6, putative 0.0248 0.1433 0.1823
Plasmodium falciparum cysteine proteinase falcipain 3 0.0043 0.0133 0.0167
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0042 0.0129 0.0085
Echinococcus granulosus hypothetical protein 0.0071 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Giardia lamblia 20S proteasome alpha subunit 1 0.0248 0.1433 0.1759
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Leishmania major proteasome alpha 7 subunit, putative 0.0248 0.1433 0.179
Echinococcus granulosus biogenic amine 5HT receptor 0.0071 0.0315 0.0378
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0034 0.0031
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0067 0.0289 0.0289
Echinococcus multilocularis ecdysone induced protein 78C 0.0137 0.0734 0.0734
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0248 0.1433 0.1807
Leishmania major proteasome beta-1 subunit, putative 0.0248 0.1433 0.179
Trypanosoma cruzi cysteine peptidase, putative 0.0162 0.0891 0.1132
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0121 0.0152
Trypanosoma brucei proteasome beta 6 subunit 0.098 0.6073 0.773
Echinococcus multilocularis mitogen activated protein kinase 3 0.0036 0.0093 0.0093
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0323 0.0409
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0039 0.011 0.0118
Brugia malayi RE15519p 0.0071 0.0315 0.0399
Mycobacterium ulcerans beta-lactamase 0.0079 0.0365 0.0388
Brugia malayi pregnancy-associated plasma protein-A 0.0067 0.0288 0.0365
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0022 0.0002 0.0002
Plasmodium vivax thioredoxin reductase, putative 0.0091 0.044 0.0558
Echinococcus granulosus cyclin B 0.0051 0.0188 0.0226
Giardia lamblia Proteasome subunit beta type 5 precursor 0.1261 0.7856 1
Brugia malayi neuropeptide F receptor 0.0071 0.0315 0.0399
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0081
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0039 0.011 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0557 0.0583
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0042 0.0129 0.0161
Onchocerca volvulus 0.015 0.0813 0.1324
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0056 0.0218 0.0256
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0365 0.0383
Loa Loa (eye worm) jmjC domain-containing protein 0.0104 0.0525 0.0657
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0248 0.1433 0.1815
Plasmodium falciparum cyclin 0.0032 0.0066 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0052 0.0192 0.0242
Echinococcus granulosus alpha 1A adrenergic receptor 0.0071 0.0315 0.0378
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0191 0.1076 0.136
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0137 0.0734 0.0932
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Schistosoma mansoni steroid hormone receptor ad4bp 0.0137 0.0734 0.0769
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0071 0.0315 0.0378
Echinococcus granulosus cathepsin l1 0.0043 0.0133 0.0159
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0063 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Brugia malayi nuclear hormone receptor 0.0137 0.0734 0.0932
Brugia malayi Dopamine receptor 0.0071 0.0315 0.0399
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0248 0.1433 0.1502
Onchocerca volvulus 0.0067 0.0288 0.0421
Schistosoma mansoni intermediate filament proteins 0.013 0.0688 0.072
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0042 0.0129 0.0072
Echinococcus granulosus g protein coupled receptor 0.0071 0.0315 0.0378
Echinococcus granulosus integrin alpha ps 0.0066 0.0284 0.0341
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trichomonas vaginalis cyclins, putative 0.0027 0.0034 0.0041
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Brugia malayi Glycosyl hydrolases family 31 protein 0.0133 0.0705 0.0895
Leishmania major cathepsin L-like protease 0.0162 0.0891 0.1096
Brugia malayi hypothetical protein 0.0065 0.0274 0.0346
Plasmodium vivax JmjC domain containing protein 0.0027 0.0034 0.004
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0042 0.0129 0.0085
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) G-protein coupled receptor 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0063 0.0261 0.0321
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0206 0.1168 0.1485
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0248 0.1433 0.1748
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Giardia lamblia Furin precursor putative serine protease 0.019 0.1066 0.1287
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0137 0.0734 0.0932
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0248 0.1433 0.1433
Schistosoma mansoni hypothetical protein 0.0452 0.273 0.286
Leishmania major cyclin 0.0051 0.0188 0.0197
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.004 0.0116 0.0139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0248 0.1437 0.1828
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Plasmodium falciparum subtilisin-like protease 3 0.0042 0.0129 0.0161
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0248 0.1433 0.1502
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0073 0.0013
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0155 0.0106
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0023 0.0024
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0022 0.0025
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0278 0.1624 0.1701
Plasmodium vivax acyl-CoA synthetase, putative 0.0034 0.0082 0.0101
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0034 0.0035
Loa Loa (eye worm) hypothetical protein 0.0089 0.043 0.0536
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0208 0.1179 0.1421
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0248 0.1433 0.1823
Plasmodium falciparum proteasome subunit beta type-1, putative 0.098 0.6073 0.773
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0607 0.3711 0.3887
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0365 0.0388
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.1433 0.1823
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0071 0.0315 0.033
Echinococcus multilocularis fmrfamide receptor 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0034 0.0021
Giardia lamblia 20S proteasome alpha subunit 7 0.0248 0.1433 0.1759
Echinococcus granulosus ubiquitin specific protease 41 0.0052 0.0192 0.023
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0063 0.0078
Echinococcus multilocularis integrin alpha 3 0.0114 0.0583 0.0583
Loa Loa (eye worm) neuropeptide F receptor 0.0071 0.0315 0.039
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0081
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0365 0.0462
Loa Loa (eye worm) nuclear receptor NHR-67 0.0065 0.0274 0.0337
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0063 0.0078
Echinococcus multilocularis membrane bound transcription factor site 1 0.0042 0.0129 0.0129
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0245 0.0294
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Schistosoma mansoni neuropeptide receptor 0.0071 0.0315 0.033
Echinococcus granulosus cathepsin L 0.0022 0.0002 0.0002
Trypanosoma cruzi 20S proteasome subunit 0.0607 0.3711 0.4722
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Plasmodium falciparum SET domain protein, putative 0.0078 0.0358 0.0453
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0071 0.0315 0.0315
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0192 0.0242
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0068 0.0296 0.0355
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0248 0.1433 0.1815
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Schistosoma mansoni RAR-like nuclear receptor 0.0137 0.0734 0.0769
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0116 0.0601 0.0678
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0034 0.0034

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) > 50 % Inhibition of HIV-1 Protease ChEMBL. 8423599
Inhibition (binding) > 50 % Inhibition of HIV-1 Protease ChEMBL. 8423599

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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