Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.189 | 0.4897 | 0.4895 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0073 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0004 | 0.0004 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0018 | 0.0014 |
Plasmodium vivax | unspecified product | 0.1025 | 0.2644 | 0.5329 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0167 | 0.041 | 0.6343 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0073 | 0.0073 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.059 | 0.1511 | 0.1511 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1491 | 0.3858 | 0.7846 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0018 | 0.0018 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0004 | 0.0003 |
Brugia malayi | cathepsin L precursor | 0.0435 | 0.1107 | 0.1107 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.1107 | 0.1107 |
Toxoplasma gondii | hypothetical protein | 0.0051 | 0.0108 | 0.0072 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0004 | 0.0004 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.1107 | 0.1107 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0057 | 0.0057 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0068 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0004 | 0.0003 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0317 | 0.08 | 0.1507 |
Brugia malayi | Cathepsin L-like precursor | 0.189 | 0.4897 | 0.4897 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.1025 | 0.2644 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.189 | 0.4897 | 0.4897 |
Entamoeba histolytica | cysteine proteinase 2 | 0.1025 | 0.2644 | 0.4054 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0073 | 0.0073 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0435 | 0.1107 | 0.2144 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0435 | 0.1107 | 0.1042 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0004 | 0.0003 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0435 | 0.1107 | 0.1107 |
Onchocerca volvulus | Cathepsin L homolog | 0.189 | 0.4897 | 1 |
Onchocerca volvulus | 0.189 | 0.4897 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Brugia malayi | cathepsin L-like precursor | 0.13 | 0.3361 | 0.3361 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0435 | 0.1107 | 0.1107 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.1025 | 0.2644 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0004 | 0.0004 |
Brugia malayi | Papain family cysteine protease containing protein | 0.189 | 0.4897 | 0.4897 |
Echinococcus multilocularis | cysteine protease | 0.189 | 0.4897 | 0.4897 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0004 | 0.0003 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0435 | 0.1107 | 0.2256 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0062 | 0.0061 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0435 | 0.1107 | 0.2144 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0435 | 0.1107 | 0.1107 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0004 | 0.0003 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.189 | 0.4897 | 0.4897 |
Onchocerca volvulus | 0.0038 | 0.0073 | 0.0142 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0073 | 0.0073 |
Toxoplasma gondii | cathepsin B | 0.1491 | 0.3858 | 0.7846 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0435 | 0.1107 | 0.1107 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0073 | 0.0073 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Plasmodium vivax | vivapain-3 | 0.1025 | 0.2644 | 0.5329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.13 | 0.3361 | 0.6815 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0004 | 0.0004 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0073 | 0.007 |
Plasmodium vivax | unspecified product | 0.059 | 0.1511 | 0.2981 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.1107 | 0.1107 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.059 | 0.1511 | 0.1511 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.189 | 0.4897 | 0.4859 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0018 | 0.0014 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.13 | 0.3361 | 0.6815 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Loa Loa (eye worm) | cathepsin B | 0.1491 | 0.3858 | 0.3858 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.385 | 1 | 1 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0435 | 0.1107 | 0.1107 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1025 | 0.2644 | 0.5329 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.189 | 0.4897 | 0.4897 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0435 | 0.1107 | 0.2144 |
Entamoeba histolytica | cysteine proteinase, putative | 0.189 | 0.4897 | 1 |
Leishmania major | cathepsin L-like protease | 0.189 | 0.4897 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.059 | 0.1511 | 0.1511 |
Leishmania major | cathepsin L-like protease | 0.189 | 0.4897 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.189 | 0.4897 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Toxoplasma gondii | cathepsin CPC1 | 0.0435 | 0.1107 | 0.2144 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0435 | 0.1107 | 0.2144 |
Echinococcus granulosus | cathepsin l1 | 0.13 | 0.3361 | 0.336 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.13 | 0.3361 | 0.3361 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0004 | 0.0003 |
Echinococcus granulosus | geminin | 0.0186 | 0.0459 | 0.0459 |
Brugia malayi | Cathepsin L-like precursor | 0.189 | 0.4897 | 0.4897 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0073 | 0.0073 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0091 | 0.0018 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.189 | 0.4897 | 0.4897 |
Entamoeba histolytica | cysteine proteinase, putative | 0.189 | 0.4897 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1025 | 0.2644 | 0.2589 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0111 | 0.0111 |
Echinococcus multilocularis | cathepsin L | 0.0435 | 0.1107 | 0.1107 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.0459 | 0.0455 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0004 | 0.0003 |
Onchocerca volvulus | 0.189 | 0.4897 | 1 | |
Onchocerca volvulus | 0.0435 | 0.1107 | 0.2256 | |
Plasmodium vivax | vivapain-1 | 0.1025 | 0.2644 | 0.5329 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1025 | 0.2644 | 0.4054 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.189 | 0.4897 | 0.4859 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0435 | 0.1107 | 0.2144 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1025 | 0.2644 | 0.5329 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.059 | 0.1511 | 0.1448 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0004 | 0.0004 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1025 | 0.2644 | 0.5329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.189 | 0.4897 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.059 | 0.1511 | 0.1448 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0435 | 0.1107 | 0.1107 |
Leishmania major | cathepsin L-like protease | 0.189 | 0.4897 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0004 | 0.0003 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0067 | 0.0149 | 0.0145 |
Leishmania major | cathepsin L-like protease | 0.189 | 0.4897 | 1 |
Plasmodium vivax | unspecified product | 0.0435 | 0.1107 | 0.2144 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0073 | 0.007 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.189 | 0.4897 | 0.4897 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0018 | 0.0018 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0435 | 0.1107 | 0.1107 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0004 | 0.0004 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0004 | 0.0004 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1025 | 0.2644 | 0.2589 |
Loa Loa (eye worm) | hypothetical protein | 0.059 | 0.1511 | 0.1511 |
Echinococcus multilocularis | cathepsin b | 0.385 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0004 | 0.0003 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0435 | 0.1107 | 0.2144 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0004 | 0.0004 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0111 | 0.0111 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.189 | 0.4897 | 0.4859 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.015 | 0.0366 | 0.0606 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Entamoeba histolytica | cysteine proteinase, putative | 0.13 | 0.3361 | 0.5946 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0004 | 0.0003 |
Giardia lamblia | Cathepsin B precursor | 0.1491 | 0.3858 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0004 | 0.0003 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0435 | 0.1107 | 0.1107 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0004 | 0.0003 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0004 | 0.0004 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1025 | 0.2644 | 0.2644 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.1107 | 0.1107 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0068 | 0.0064 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0317 | 0.08 | 0.0732 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.1107 | 0.1107 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0004 | 0.0003 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.13 | 0.3361 | 0.3312 |
Brugia malayi | Cathepsin L-like precursor | 0.13 | 0.3361 | 0.3361 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0045 | 0.0091 | 0.0018 |
Brugia malayi | Cathepsin L-like precursor | 0.189 | 0.4897 | 0.4897 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.013 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0004 | 0.0003 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1491 | 0.3858 | 0.7846 |
Mycobacterium ulcerans | hypothetical protein | 0.0167 | 0.041 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1025 | 0.2644 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0054 | 0.0116 | 0.0043 |
Echinococcus multilocularis | cysteine protease | 0.189 | 0.4897 | 0.4897 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0004 | 0.0003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.059 | 0.1511 | 0.1511 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0062 | 0.0061 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.189 | 0.4897 | 1 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0435 | 0.1107 | 0.1107 |
Schistosoma mansoni | cathepsin s | 0.059 | 0.1511 | 0.1508 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0018 | 0.0018 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.189 | 0.4897 | 0.4895 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Onchocerca volvulus | 0.13 | 0.3361 | 0.686 | |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.385 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0073 | 0.0073 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.189 | 0.4897 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0004 | 0.0003 |
Giardia lamblia | Cathepsin B precursor | 0.1491 | 0.3858 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0004 | 0.0003 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1025 | 0.2644 | 0.2589 |
Loa Loa (eye worm) | hypothetical protein | 0.13 | 0.3361 | 0.336 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0018 | 0.0018 |
Onchocerca volvulus | 0.0038 | 0.0073 | 0.0142 | |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0435 | 0.1107 | 0.2144 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0057 | 0.0057 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0018 | 0.0014 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1025 | 0.2644 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0317 | 0.08 | 0.0732 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1025 | 0.2644 | 0.4054 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0018 | 0.0018 |
Echinococcus granulosus | cysteine protease | 0.1025 | 0.2644 | 0.2643 |
Brugia malayi | Cathepsin L-like precursor | 0.189 | 0.4897 | 0.4897 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0004 | 0.0003 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.13 | 0.3361 | 0.336 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0004 | 0.0003 |
Leishmania major | cathepsin L-like protease | 0.189 | 0.4897 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0435 | 0.1107 | 0.2144 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0073 | 0.0073 |
Plasmodium vivax | vivapain-2 | 0.189 | 0.4897 | 1 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0435 | 0.1107 | 0.2144 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0004 | 0.0004 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0073 | 0.0073 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1025 | 0.2644 | 0.2641 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.1491 | 0.3858 | 0.7846 |
Loa Loa (eye worm) | hypothetical protein | 0.059 | 0.1511 | 0.1511 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0004 | 0.0003 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0435 | 0.1107 | 0.2144 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1025 | 0.2644 | 0.5329 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.385 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0091 | 0.0018 |
Toxoplasma gondii | cathepsin CPL | 0.189 | 0.4897 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.059 | 0.1511 | 0.1511 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0073 | 0.0073 |
Onchocerca volvulus | 0.0038 | 0.0073 | 0.0142 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0435 | 0.1107 | 0.2144 |
Echinococcus granulosus | cathepsin L | 0.1025 | 0.2644 | 0.2643 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0062 | 0.0058 |
Loa Loa (eye worm) | ctsf protein | 0.189 | 0.4897 | 0.4897 |
Brugia malayi | Cathepsin L-like precursor | 0.189 | 0.4897 | 0.4897 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0004 | 0.0003 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0073 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.189 | 0.4897 | 0.4859 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0045 | 0.0091 | 0.0037 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1491 | 0.3858 | 0.3812 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Loa Loa (eye worm) | fibroinase | 0.189 | 0.4897 | 0.4897 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0073 | 0.0073 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.189 | 0.4897 | 0.4897 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0004 | 0.0003 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.015 | 0.0366 | 0.0294 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0004 | 0.0004 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0111 | 0.0111 |
Toxoplasma gondii | cathepsin CPC2 | 0.0435 | 0.1107 | 0.2144 |
Onchocerca volvulus | 0.189 | 0.4897 | 1 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1025 | 0.2644 | 0.2641 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.015 | 0.0366 | 0.0606 |
Echinococcus granulosus | cathepsin b | 0.385 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Onchocerca volvulus | 0.189 | 0.4897 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.385 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Onchocerca volvulus | 0.189 | 0.4897 | 1 | |
Loa Loa (eye worm) | cysteine protease | 0.189 | 0.4897 | 0.4897 |
Loa Loa (eye worm) | hypothetical protein | 0.13 | 0.3361 | 0.336 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0073 | 0.0073 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0073 | 0.0073 |
Onchocerca volvulus | 0.189 | 0.4897 | 1 | |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0435 | 0.1107 | 0.2144 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0004 | 0.0003 |
Echinococcus multilocularis | cathepsin b | 0.385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0004 | 0.0004 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.189 | 0.4897 | 0.4897 |
Brugia malayi | Cathepsin L-like precursor | 0.13 | 0.3361 | 0.3361 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.189 | 0.4897 | 0.4897 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0004 | 0.0004 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0004 | 0.0004 |
Onchocerca volvulus | 0.0032 | 0.0057 | 0.0109 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0004 | 0.0003 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0018 | 0.0018 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0073 | 0.0073 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.189 | 0.4897 | 0.4897 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1025 | 0.2644 | 0.2644 |
Trypanosoma cruzi | cysteine protease, putative | 0.1025 | 0.2644 | 0.2589 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.189 | 0.4897 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0435 | 0.1107 | 0.2144 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0435 | 0.1107 | 0.2144 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0062 | 0.0058 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Leishmania major | cathepsin L-like protease | 0.189 | 0.4897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0073 | 0.0073 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0057 | 0.0053 |
Echinococcus granulosus | cathepsin l1 | 0.189 | 0.4897 | 0.4897 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0004 | 0.0004 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.13 | 0.3361 | 0.3358 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Leishmania major | cathepsin L-like protease | 0.189 | 0.4897 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Schistosoma mansoni | cathepsin C | 0.0435 | 0.1107 | 0.1104 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0004 | 0.0003 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0317 | 0.08 | 0.1507 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.189 | 0.4897 | 0.4897 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0435 | 0.1107 | 0.1107 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.0459 | 0.0455 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0068 | 0.0068 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.1025 | 0.2644 | 0.2643 |
Onchocerca volvulus | 0.189 | 0.4897 | 1 | |
Echinococcus multilocularis | geminin | 0.0186 | 0.0459 | 0.0459 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.189 | 0.4897 | 0.4859 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.385 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0004 | 0.0004 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0435 | 0.1107 | 0.2144 |
Loa Loa (eye worm) | hypothetical protein | 0.385 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0004 | 0.0004 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0435 | 0.1107 | 0.1042 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0435 | 0.1107 | 0.2144 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1491 | 0.3858 | 0.3855 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Brugia malayi | fibroinase precursor | 0.0435 | 0.1107 | 0.1107 |
Echinococcus multilocularis | cathepsin L | 0.1025 | 0.2644 | 0.2643 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0004 | 0.0004 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.1107 | 0.1107 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.189 | 0.4897 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1025 | 0.2644 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.1491 | 0.3858 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0241 | 0.0604 | 1 |
Leishmania major | cathepsin L-like protease | 0.189 | 0.4897 | 1 |
Echinococcus granulosus | cathepsin L | 0.0435 | 0.1107 | 0.1107 |
Onchocerca volvulus | Cathepsin F homolog | 0.189 | 0.4897 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.1025 | 0.2644 | 0.2589 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1025 | 0.2644 | 0.2641 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.189 | 0.4897 | 1 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0435 | 0.1107 | 0.1107 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0004 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0018 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0111 | 0.0111 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0004 | 0.0003 |
Onchocerca volvulus | Cathepsin L homolog | 0.189 | 0.4897 | 1 |
Plasmodium vivax | vivapain-2 | 0.189 | 0.4897 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0004 | 0.0003 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0435 | 0.1107 | 0.1104 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.