Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Cathepsin B precursor | 0.1645 | 0.1677 | 0.5 |
Loa Loa (eye worm) | cysteine protease | 0.2063 | 0.3006 | 0.2266 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1645 | 0.1677 | 0.5579 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2063 | 0.3006 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2063 | 0.3006 | 0.3006 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.2063 | 0.3006 | 0.3006 |
Echinococcus granulosus | cathepsin l1 | 0.1419 | 0.0956 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.2063 | 0.3006 | 0.2266 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.2063 | 0.3006 | 0.2266 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Echinococcus multilocularis | cathepsin b | 0.4257 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.2063 | 0.3006 | 1 |
Echinococcus multilocularis | cysteine protease | 0.2063 | 0.3006 | 0.3006 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1419 | 0.0956 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Loa Loa (eye worm) | fibroinase | 0.2063 | 0.3006 | 0.2266 |
Leishmania major | cathepsin L-like protease | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1419 | 0.0956 | 0.0956 |
Onchocerca volvulus | 0.2063 | 0.3006 | 1 | |
Leishmania major | cathepsin L-like protease | 0.2063 | 0.3006 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2063 | 0.3006 | 0.3006 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1645 | 0.1677 | 0.1677 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1645 | 0.1677 | 0.5 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.2063 | 0.3006 | 0.3006 |
Onchocerca volvulus | Cathepsin L homolog | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.2063 | 0.3006 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1419 | 0.0956 | 0.0956 |
Echinococcus granulosus | cathepsin b | 0.4257 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.4257 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2063 | 0.3006 | 0.3006 |
Plasmodium vivax | vivapain-2 | 0.2063 | 0.3006 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.2063 | 0.3006 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.4257 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Onchocerca volvulus | 0.2063 | 0.3006 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.2063 | 0.3006 | 0.3006 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.4257 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1419 | 0.0956 | 0.0956 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.4257 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.4257 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1419 | 0.0956 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2063 | 0.3006 | 0.3006 |
Onchocerca volvulus | 0.2063 | 0.3006 | 1 | |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1419 | 0.0956 | 0.0956 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.2063 | 0.3006 | 0.3006 |
Onchocerca volvulus | Cathepsin F homolog | 0.2063 | 0.3006 | 1 |
Leishmania major | cathepsin L-like protease | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1419 | 0.0956 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.1419 | 0.0956 | 0.0956 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2063 | 0.3006 | 0.3006 |
Onchocerca volvulus | Cathepsin L homolog | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Plasmodium vivax | vivapain-2 | 0.2063 | 0.3006 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2063 | 0.3006 | 0.3006 |
Giardia lamblia | Cathepsin B precursor | 0.1645 | 0.1677 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.2063 | 0.3006 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.1419 | 0.0956 | 0.0956 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1645 | 0.1677 | 0.5579 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.2063 | 0.3006 | 0.2266 |
Brugia malayi | Cathepsin L-like precursor | 0.2063 | 0.3006 | 0.3006 |
Leishmania major | cathepsin L-like protease | 0.2063 | 0.3006 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Onchocerca volvulus | 0.2063 | 0.3006 | 1 | |
Onchocerca volvulus | 0.2063 | 0.3006 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.2063 | 0.3006 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2063 | 0.3006 | 0.3006 |
Loa Loa (eye worm) | hypothetical protein | 0.4257 | 1 | 1 |
Onchocerca volvulus | 0.2063 | 0.3006 | 1 | |
Loa Loa (eye worm) | cathepsin B | 0.1645 | 0.1677 | 0.0797 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Leishmania major | cathepsin L-like protease | 0.2063 | 0.3006 | 1 |
Echinococcus multilocularis | cysteine protease | 0.2063 | 0.3006 | 0.3006 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2063 | 0.3006 | 0.3006 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2063 | 0.3006 | 0.3006 |
Leishmania major | cathepsin L-like protease | 0.2063 | 0.3006 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2063 | 0.3006 | 1 |
Onchocerca volvulus | 0.2063 | 0.3006 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.2063 | 0.3006 | 0.3006 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2063 | 0.3006 | 0.3006 |
Brugia malayi | Papain family cysteine protease containing protein | 0.2063 | 0.3006 | 0.3006 |
Leishmania major | cysteine peptidase A (CPA) | 0.2063 | 0.3006 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.2063 | 0.3006 | 0.2266 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.2063 | 0.3006 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2063 | 0.3006 | 0.3006 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2063 | 0.3006 | 0.3006 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.4257 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2063 | 0.3006 | 0.3006 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2063 | 0.3006 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2063 | 0.3006 | 0.3006 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.4257 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1645 | 0.1677 | 0.1677 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.