Detailed information for compound 163067

Basic information

Technical information
  • TDR Targets ID: 163067
  • Name: benzyl N-[(2S)-4-amino-1-[[(2S,3R)-3-hydroxy- 4-[methylcarbamoyl(2-methylpropyl)amino]-1-ph enylbutan-2-yl]amino]-1,4-dioxobutan-2-yl]car bamate
  • MW: 541.639 | Formula: C28H39N5O6
  • H donors: 5 H acceptors: 5 LogP: 1.73 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 2
  • SMILES: CNC(=O)N(C[C@H]([C@@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)CC(=O)N)Cc1ccccc1)O)CC(C)C
  • InChi: 1S/C28H39N5O6/c1-19(2)16-33(27(37)30-3)17-24(34)22(14-20-10-6-4-7-11-20)31-26(36)23(15-25(29)35)32-28(38)39-18-21-12-8-5-9-13-21/h4-13,19,22-24,34H,14-18H2,1-3H3,(H2,29,35)(H,30,37)(H,31,36)(H,32,38)/t22-,23-,24+/m0/s1
  • InChiKey: KGHZDRBKSVQHQS-KMDXXIMOSA-N  

Network

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Synonyms

  • benzyl N-[(1S)-3-amino-1-[[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl(methylcarbamoyl)amino]propyl]carbamoyl]-3-oxo-propyl]carbamate
  • N-[(1S)-3-amino-1-[[[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl(methylcarbamoyl)amino]propyl]amino]-oxomethyl]-3-oxopropyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-4-azanyl-1-[[(2S,3R)-3-hydroxy-4-[methylcarbamoyl(2-methylpropyl)amino]-1-phenyl-butan-2-yl]amino]-1,4-dioxo-butan-2-yl]carbamate
  • N-[(1S)-3-amino-1-[[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl(methylcarbamoyl)amino]propyl]carbamoyl]-3-keto-propyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-4-amino-1-[[(2S,3R)-3-hydroxy-4-(methylcarbamoyl-(2-methylpropyl)amino)-1-phenylbutan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamate
  • phenylmethyl N-[(1S)-3-amino-1-[[(1S,2R)-2-hydroxy-3-(isobutyl-(methylcarbamoyl)amino)-1-(phenylmethyl)propyl]carbamoyl]-3-oxo-propyl]carbamate
  • N-[(1S)-3-amino-1-[[[(1S,2R)-2-hydroxy-3-(isobutyl-(methylcarbamoyl)amino)-1-(phenylmethyl)propyl]amino]-oxomethyl]-3-oxopropyl]carbamic acid phenylmethyl ester
  • N-[(1S)-3-amino-1-[[(1S,2R)-1-(benzyl)-2-hydroxy-3-(isobutyl-(methylcarbamoyl)amino)propyl]carbamoyl]-3-keto-propyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-4-amino-1-[[(2S,3R)-3-hydroxy-4-(methylcarbamoyl-(2-methylpropyl)amino)-1-phenyl-butan-2-yl]amino]-1,4-dioxo-butan-2-yl]carbamate
  • (Hydroxyethyl)urea Isostere deriv. 3
  • AIDS004513
  • N-Methyl-N'-isobutyl-N'-[[2(R)-hydroxy-4-phenyl-3(S)-[4-amino-1,4-dioxo-2(S)-[(benzyloxycarbonyl)amino]butylamino]butyl]urea
  • AIDS-004513

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 protease Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) Get druggable targets OG5_131408 All targets in OG5_131408

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Giardia lamblia DNA-directed RNA polymerase subunit D Human immunodeficiency virus type 1 protease   99 aa 90 aa 27.8 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Trypanosoma brucei variant surface glycoprotein (VSG), putative Human immunodeficiency virus type 1 protease   99 aa 80 aa 27.5 %
Mycobacterium leprae Hypothetical protein Human immunodeficiency virus type 1 protease   99 aa 86 aa 27.9 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Echinococcus multilocularis Chromobox protein 3 Human immunodeficiency virus type 1 protease   99 aa 95 aa 28.4 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium falciparum acyl-CoA synthetase 0.0034 0.0082 0.0101
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.098 0.6073 0.6361
Echinococcus multilocularis neuropeptide receptor 0.0071 0.0315 0.0315
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0063 0.0058
Onchocerca volvulus Huntingtin homolog 0.0081 0.0379 0.0576
Loa Loa (eye worm) hypothetical protein 0.0032 0.0065 0.0071
Toxoplasma gondii proteasome beta subunit 0.0248 0.1433 0.1807
Leishmania major proteasome beta 2 subunit, putative 0.0607 0.3711 0.4701
Brugia malayi Serotonin receptor 0.0071 0.0315 0.0399
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0034 0.0031
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0248 0.1433 0.1759
Plasmodium falciparum SET domain protein, putative 0.0078 0.0358 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0066 0.0082
Loa Loa (eye worm) nuclear hormone receptor 0.0065 0.0274 0.0337
Echinococcus granulosus dro:myosuppressin receptor 0.0071 0.0315 0.0378
Schistosoma mansoni histone-lysine n-methyltransferase seto7 0.0078 0.0358 0.0375
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0607 0.3711 0.4712
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0065 0.0274 0.0287
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Schistosoma mansoni site-1 peptidase (S08 family) 0.0042 0.0129 0.0135
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0248 0.1433 0.1823
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0241 0.0295
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Loa Loa (eye worm) hypothetical protein 0.015 0.0813 0.1025
Echinococcus multilocularis fmrfamide receptor 0.0071 0.0315 0.0315
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.1261 0.7856 1
Echinococcus granulosus cyclin B3 1 0.0032 0.0066 0.0079
Toxoplasma gondii subtilisin SUB9 0.0042 0.0129 0.0142
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0034 0.0034
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1528 0.9546 1
Schistosoma mansoni pyruvate kinase 0.0033 0.0073 0.0076
Schistosoma mansoni retinoic acid receptor RXR 0.0137 0.0734 0.0769
Schistosoma mansoni RAR-like nuclear receptor 0.0137 0.0734 0.0769
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0137 0.0734 0.0932
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0137 0.0734 0.0932
Onchocerca volvulus Bile acid receptor homolog 0.0137 0.0734 0.1187
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0034 0.004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0031
Entamoeba histolytica cyclin, putative 0.0032 0.0066 0.0082
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Brugia malayi hypothetical protein 0.0106 0.0533 0.0677
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0248 0.1437 0.1828
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.004 0.0116 0.0116
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0248 0.1433 0.1823
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0068 0.0296 0.0355
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0052 0.0192 0.0242
Echinococcus multilocularis proteasome subunit alpha type 6 0.0248 0.1433 0.1433
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0365 0.0462
Onchocerca volvulus 0.0051 0.0188 0.0248
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0248 0.1433 0.1502
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0248 0.1433 0.1502
Leishmania major cathepsin L-like protease 0.0162 0.0891 0.1096
Echinococcus multilocularis cyclin B 0.0051 0.0188 0.0188
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0155 0.0119
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0073 0.009
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Echinococcus granulosus intermediate filament protein 0.013 0.0688 0.0825
Toxoplasma gondii proteasome subunit 0.0248 0.1433 0.1807
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0155 0.0119
Plasmodium vivax proteasome subunit beta type-4, putative 0.0248 0.1433 0.1823
Schistosoma mansoni c4b-binding protein beta chain 0.0067 0.0288 0.0302
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0121 0.0152
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0042 0.0129 0.0072
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Schistosoma mansoni pyruvate kinase 0.0033 0.0073 0.0076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0155 0.0195
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0206 0.1168 0.1485
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0157
Giardia lamblia 20S proteasome alpha subunit 6 0.0248 0.1433 0.1759
Loa Loa (eye worm) cyclin domain-containing protein 0.0032 0.0066 0.0073
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0055 0.0055
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0056 0.0218 0.0186
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0063 0.0078
Mycobacterium tuberculosis Conserved hypothetical protein 0.0108 0.0551 0.0626
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0274 0.0287
Echinococcus granulosus c4b binding protein beta chain 0.0067 0.0288 0.0346
Onchocerca volvulus 0.0039 0.011 0.0114
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0042 0.0129 0.0135
Loa Loa (eye worm) ctsf protein 0.0043 0.0133 0.0157
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0581 0.0697
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0607 0.3711 0.4722
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0071 0.0315 0.033
Echinococcus granulosus g-protein coupled receptor 0.0071 0.0315 0.0378
Brugia malayi putative neuropeptide receptor 0.0071 0.0315 0.0399
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0063 0.0037
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0122 0.0639 0.0639
Echinococcus granulosus neutral alpha glucosidase AB 0.0029 0.005 0.006
Echinococcus granulosus membrane bound transcription factor site 1 0.0042 0.0129 0.0154
Brugia malayi proteasome subunit alpha type 3 0.0248 0.1433 0.1823
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0071 0.0315 0.0399
Brugia malayi proteasome subunit beta type 3 0.0248 0.1433 0.1823
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Schistosoma mansoni hypothetical protein 0.0091 0.0439 0.046
Trypanosoma cruzi CYC2-like cyclin, putative 0.0051 0.0188 0.0237
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 1
Onchocerca volvulus 0.0071 0.0315 0.0467
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0248 0.1433 0.1823
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0056 0.0218 0.0256
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0232 0.1332 0.1395
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0073 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0022 0.0002 0.0002
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.1261 0.7856 1
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0155 0.0195
Echinococcus multilocularis neuropeptide Y receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis cysteine protease 0.0043 0.0133 0.0133
Toxoplasma gondii subtilisin SUB1 0.0042 0.0129 0.0142
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Mycobacterium tuberculosis Probable dehydrogenase 0.0208 0.1179 0.1432
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Toxoplasma gondii subtilisin SUB2 0.0042 0.0129 0.0142
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0042 0.0129 0.0161
Treponema pallidum hypothetical protein 0.0039 0.011 0.0357
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0042 0.0129 0.0161
Brugia malayi hypothetical protein 0.0065 0.0274 0.0346
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0034 0.0034
Onchocerca volvulus 0.0067 0.0288 0.0421
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Plasmodium falciparum glutathione reductase 0.0091 0.044 0.0558
Onchocerca volvulus 0.0071 0.0315 0.0467
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Loa Loa (eye worm) proteasome subunit beta type 2 0.0607 0.3711 0.4717
Loa Loa (eye worm) calpain family protein 1 0.0064 0.0268 0.033
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0063 0.0078
Plasmodium falciparum subtilisin-like protease 3 0.0042 0.0129 0.0161
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0036 0.0093 0.0076
Trichomonas vaginalis sucrase-isomaltase, putative 0.0029 0.005 0.0061
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Onchocerca volvulus Huntingtin homolog 0.0081 0.0379 0.0576
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0248 0.1433 1
Loa Loa (eye worm) hypothetical protein 0.0446 0.2688 0.3413
Giardia lamblia 20S proteasome alpha subunit 7 0.0248 0.1433 0.1759
Echinococcus multilocularis 0.0791 0.4879 0.4879
Trichomonas vaginalis cyclin A, putative 0.0051 0.0188 0.0237
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus multilocularis g protein coupled receptor 0.0071 0.0315 0.0315
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0063 0.0078
Plasmodium vivax thioredoxin reductase, putative 0.0091 0.044 0.0558
Trichomonas vaginalis cyclin D, putative 0.0032 0.0066 0.0082
Loa Loa (eye worm) hypothetical protein 0.0089 0.043 0.0536
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0155 0.0119
Leishmania major proteasome beta 2 subunit, putative 0.0248 0.1433 0.179
Loa Loa (eye worm) hypothetical protein 0.0131 0.0692 0.087
Echinococcus multilocularis neuropeptides capa receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0067 0.0289 0.0289
Plasmodium vivax SET domain protein, putative 0.0078 0.0358 0.0453
Plasmodium falciparum apical sushi protein 0.0067 0.0288 0.0365
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0041 0.0125 0.0125
Mycobacterium ulcerans lipase LipD 0.0079 0.0365 0.0388
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0274 0.0287
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Echinococcus granulosus peptidase Clp S14 family 0.0037 0.0096 0.0115
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0009 0.0009
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni opsin-like receptor 0.0071 0.0315 0.033
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0073 0.0323 0.0387
Giardia lamblia 20S proteasome alpha subunit 1 0.0248 0.1433 0.1759
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0155 0.0119
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0042 0.0129 0.0129
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0116 0.0121
Echinococcus multilocularis cathepsin L 0.0022 0.0002 0.0002
Loa Loa (eye worm) neuropeptide F receptor 0.0071 0.0315 0.039
Brugia malayi proteasome subunit beta type 1 0.098 0.6073 0.773
Schistosoma mansoni hypothetical protein 0.0452 0.273 0.286
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0248 0.1433 0.1502
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0116 0.0601 0.0678
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0043 0.0133 0.0167
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0042 0.0129 0.0085
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0365 0.0383
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0155 0.0156
Brugia malayi nuclear receptor RXR 0.0073 0.0323 0.0409
Schistosoma mansoni cyclin B3 0.0032 0.0066 0.0069
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0073 0.009
Echinococcus granulosus cathepsin l cysteine peptidase 0.0043 0.0133 0.0159
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0167 0.0134
Onchocerca volvulus 0.0122 0.0639 0.1024
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0248 0.1433 0.1748
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0121 0.0152
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0248 0.1433 0.179
Echinococcus granulosus proteasome prosome macropain subunit beta 0.098 0.6073 0.7283
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0071 0.0315 0.0399
Echinococcus granulosus cyclin b3 0.0032 0.0066 0.0079
Loa Loa (eye worm) hypothetical protein 0.0046 0.0155 0.0186
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Loa Loa (eye worm) beta-lactamase 0.0079 0.0365 0.0454
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Trypanosoma cruzi major cysteine proteinase, putative 0.0127 0.0671 0.0852
Plasmodium falciparum thioredoxin reductase 0.0032 0.0063 0.0078
Onchocerca volvulus 0.0071 0.0315 0.0467
Brugia malayi cytoplasmic intermediate filament protein 0.007 0.0305 0.0386
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0037 0.0096 0.0042
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0248 0.1433 0.1759
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.005
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0581 0.0581
Echinococcus granulosus cysteine protease 0.0022 0.0002 0.0002
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0034 0.0035
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0137 0.0734 0.0923
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.0051 0.0188 0.0228
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0248 0.1433 0.1502
Brugia malayi Serotonin receptor 0.0071 0.0315 0.0399
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Loa Loa (eye worm) hypothetical protein 0.0046 0.0155 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0137 0.0734 0.0932
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0042 0.0129 0.0072
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0832 0.5133 0.6531
Echinococcus granulosus peptide allatostatin:somatostatin 0.0071 0.0315 0.0378
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0098 0.0485 0.0485
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Onchocerca volvulus 0.0065 0.0274 0.0396
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0365 0.0438
Echinococcus granulosus furin 0.0981 0.6082 0.7294
Brugia malayi TAR-binding protein 0.0191 0.1076 0.1368
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis dro:myosuppressin receptor 0.0071 0.0315 0.0315
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0042 0.0129 0.0135
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0063 0.0037
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0245 0.0234
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0044 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Onchocerca volvulus 0.0067 0.0288 0.0421
Brugia malayi beta-lactamase family protein 0.0079 0.0365 0.0462
Toxoplasma gondii histone lysine methyltransferase SET8 0.0078 0.0358 0.0435
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0607 0.3711 0.3711
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Brugia malayi MAP kinase sur-1 0.0036 0.0093 0.0116
Plasmodium vivax JmjC domain containing protein 0.0027 0.0034 0.004
Echinococcus multilocularis nuclear receptor nhr 48 0.0065 0.0274 0.0274
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0068 0.0296 0.0296
Giardia lamblia Proteasome subunit beta type 1 0.098 0.6073 0.7712
Loa Loa (eye worm) leukotriene A4 hydrolase 0.023 0.1321 0.1672
Leishmania major cathepsin L-like protease 0.0162 0.0891 0.1096
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.004 0.0116 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0063 0.0078
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0073 0.009
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0708 0.0742
Toxoplasma gondii subtilisin SUB11 0.0042 0.0129 0.0142
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0199
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0261
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Onchocerca volvulus 0.0045 0.0148 0.0179
Echinococcus multilocularis thioredoxin glutathione reductase 0.0091 0.0442 0.0442
Echinococcus granulosus fmrfamide receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0039 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0056 0.0218 0.0266
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Schistosoma mansoni opsin-like receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi Cathepsin L-like precursor 0.0028 0.0044 0.0053
Echinococcus granulosus G protein coupled receptor 139 0.0071 0.0315 0.0378
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0248 0.1433 0.1433
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0065 0.0274 0.0274
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Onchocerca volvulus 0.013 0.0688 0.1108
Brugia malayi neuropeptide F receptor 0.0071 0.0315 0.0399
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0155 0.0156
Schistosoma mansoni histamine h1 receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Echinococcus multilocularis cathepsin L cysteine protease 0.0043 0.0133 0.0133
Echinococcus multilocularis transcription factor Dp 1 0.0023 0.0009 0.0009
Onchocerca volvulus 0.0071 0.0315 0.0467
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0042 0.0129 0.0161
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0365 0.0462
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.004 0.0116 0.0145
Plasmodium falciparum subtilisin-like protease 2 0.0042 0.0129 0.0161
Schistosoma mansoni survival motor neuron protein 0.0091 0.0439 0.046
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0047 0.0057
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0071 0.0315 0.0378
Onchocerca volvulus 0.0071 0.0315 0.0467
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis dnaJ subfamily B 0.0555 0.3381 0.3381
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0245 0.0245
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0137 0.0734 0.0734
Echinococcus multilocularis sex peptide receptor 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Onchocerca volvulus 0.0067 0.0288 0.0421
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0071 0.0315 0.0315
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Brugia malayi intermediate filament protein 0.013 0.0688 0.0873
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0067 0.0289 0.0303
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0036 0.0093 0.0116
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0274 0.0274
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0245 0.0234
Echinococcus granulosus GPCR family 2 0.0041 0.0125 0.015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Treponema pallidum 76K protein 0.0039 0.011 0.0357
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0208 0.1179 0.1421
Schistosoma mansoni microtubule-associated protein tau 0.1337 0.8338 0.8734
Brugia malayi nuclear hormone receptor family member nhr-6 0.0065 0.0274 0.0346
Onchocerca volvulus 0.004 0.0116 0.0124
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0052 0.0192 0.0201
Loa Loa (eye worm) hypothetical protein 0.0078 0.0358 0.0444
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0121 0.0152
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0131 0.0692 0.087
Echinococcus granulosus pyruvate kinase 0.0033 0.0073 0.0087
Echinococcus multilocularis leukotriene A 4 hydrolase 0.023 0.1321 0.1321
Brugia malayi 20S proteasome alpha5 subunit 0.0248 0.1433 0.1823
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0121 0.0075
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0137 0.0734 0.0769
Loa Loa (eye worm) CUTiclin-Like family member 0.0039 0.011 0.0128
Echinococcus granulosus mitogen activated protein kinase 0.0036 0.0093 0.0111
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0165 0.091 0.1092
Trypanosoma brucei proteasome subunit beta type-5, putative 0.1261 0.7856 1
Echinococcus granulosus leukotriene A 4 hydrolase 0.023 0.1321 0.1584
Onchocerca volvulus 0.0039 0.011 0.0114
Schistosoma mansoni integrin alpha-ps 0.0035 0.0082 0.0086
Echinococcus multilocularis G protein coupled receptor 139 0.0575 0.351 0.351
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0206 0.1168 0.1485
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0248 0.1433 0.1815
Echinococcus multilocularis g-protein coupled receptor 0.0071 0.0315 0.0315
Leishmania major proteasome beta-1 subunit, putative 0.0248 0.1433 0.179
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0245 0.0294
Brugia malayi Sushi domain 0.0067 0.0288 0.0365
Brugia malayi ORL1-like opioid receptor 0.0071 0.0315 0.0399
Onchocerca volvulus 0.0137 0.0734 0.1187
Brugia malayi Proteasome subunit alpha type 1 0.0248 0.1433 0.1823
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0137 0.0734 0.0932
Schistosoma mansoni nuclear receptor 0.0065 0.0274 0.0287
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.1348 0.1706
Brugia malayi Dopamine receptor 0.0071 0.0315 0.0399
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0066
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Echinococcus granulosus integrin alpha ps 0.0066 0.0284 0.0341
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0248 0.1433 0.1823
Echinococcus granulosus beta-adrenergic receptor kinase 0.0109 0.0557 0.0668
Onchocerca volvulus 0.0043 0.0133 0.0153
Giardia lamblia Proteasome subunit beta type 3 0.0248 0.1433 0.1759
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0506 0.3071 0.3861
Loa Loa (eye worm) hypothetical protein 0.0064 0.0268 0.033
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Plasmodium vivax thrombospondin-related anonymous protein 0.0039 0.011 0.0137
Toxoplasma gondii subtilisin SUB8 0.0042 0.0129 0.0142
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0206 0.1168 0.1485
Echinococcus granulosus survival motor neuron protein 1 0.0446 0.2688 0.3223
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0023 0.0028
Echinococcus granulosus thioredoxin glutathione reductase 0.0091 0.0442 0.053
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0248 0.1433 0.1823
Brugia malayi proprotein convertase 2 0.0617 0.3771 0.4799
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0248 0.1433 0.1502
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0071 0.0315 0.0315
Entamoeba histolytica elongation factor-2 kinase, putative 0.0039 0.011 0.0137
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0071 0.0315 0.0315
Echinococcus multilocularis thyroid hormone receptor alpha 0.0137 0.0734 0.0734
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0043 0.0133 0.0167
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0248 0.1433 0.1823
Mycobacterium ulcerans 3-dehydroquinate dehydratase 0.1162 0.7227 0.9194
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0248 0.1433 0.1823
Echinococcus granulosus histone acetyltransferase MYST2 0.0045 0.015 0.018
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.0639 0.0794
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0365 0.0462
Echinococcus multilocularis neuroendocrine convertase 2 0.0617 0.3771 0.3771
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0192 0.0242
Echinococcus multilocularis geminin 0.0452 0.273 0.273
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0068 0.0296 0.0296
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0365 0.0462
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Brugia malayi nuclear receptor NHR-88 0.0137 0.0734 0.0932
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0063 0.0261 0.0313
Schistosoma mansoni hypothetical protein 0.0555 0.3381 0.3542
Echinococcus granulosus neuropeptide receptor 0.0071 0.0315 0.0378
Schistosoma mansoni nuclear receptor 0.0065 0.0274 0.0287
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0071 0.0315 0.0315
Entamoeba histolytica cyclin family protein 0.0032 0.0066 0.0082
Brugia malayi hypothetical protein 0.0039 0.011 0.0137
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) G-protein coupled receptor 0.0071 0.0315 0.039
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0248 0.1433 0.1823
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.098 0.6073 0.7721
Brugia malayi nuclear receptor RXR 0.0065 0.0274 0.0346
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0065 0.0274 0.0346
Brugia malayi orphan nuclear receptor NR2E1 0.0065 0.0274 0.0346
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0052 0.0192 0.0242
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi CXXC zinc finger family protein 0.006 0.0241 0.0305
Loa Loa (eye worm) proprotein convertase 2 0.0232 0.1332 0.1685
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Brugia malayi photoreceptor-specific nuclear receptor 0.0137 0.0734 0.0932
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Echinococcus multilocularis proteasome subunit beta type 7 0.0248 0.1433 0.1433
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0152
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0122 0.0639 0.067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0137 0.0734 0.088
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0121 0.0152
Echinococcus multilocularis neuropeptide FF receptor 2 0.0071 0.0315 0.0315
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0248 0.1433 0.1502
Giardia lamblia 20S proteasome alpha subunit 5 0.0248 0.1433 0.1759
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0068 0.0296 0.0355
Schistosoma mansoni biogenic amine (5HT) receptor 0.0071 0.0315 0.033
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0248 0.1433 0.1502
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0071 0.0315 0.0315
Echinococcus granulosus neuroendocrine convertase 2 0.0617 0.3771 0.4522
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0155 0.0119
Trypanosoma brucei proteasome alpha 7 subunit 0.0248 0.1433 0.1823
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0365 0.0462
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0365 0.0376
Trypanosoma brucei mitotic cyclin 6 0.0051 0.0188 0.0237
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0365 0.0454
Echinococcus multilocularis lysosomal alpha glucosidase 0.0133 0.0705 0.0705
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Brugia malayi putative neuropeptide receptor NPR1 0.0071 0.0315 0.0399
Brugia malayi Zona pellucida-like domain containing protein 0.0039 0.011 0.0137
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0063 0.0078
Echinococcus multilocularis membrane bound transcription factor site 1 0.0042 0.0129 0.0129
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0048 0.0167 0.021
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0248 0.1433 0.1823
Brugia malayi Tachykinin-like peptides receptor 99D 0.0071 0.0315 0.0399
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0071 0.0315 0.0315
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0071 0.0315 0.039
Entamoeba histolytica hypothetical protein 0.0039 0.011 0.0137
Schistosoma mansoni steroid hormone receptor ad4bp 0.0137 0.0734 0.0769
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0075
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0274 0.0274
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Mycobacterium leprae Possible secreted protease 0.0042 0.0129 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Leishmania major cathepsin L-like protease 0.0162 0.0891 0.1096
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0248 0.1433 0.1823
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0068 0.0296 0.0366
Loa Loa (eye worm) G-protein coupled receptor 0.0071 0.0315 0.039
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0042 0.0129 0.0085
Plasmodium falciparum proteasome subunit beta type-4 0.0248 0.1433 0.1823
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0037 0.0096 0.0042
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Brugia malayi Latrophilin receptor protein 2 0.0041 0.0125 0.0157
Echinococcus multilocularis G-protein coupled receptor, putative 0.0071 0.0315 0.0315
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0208 0.1179 0.1432
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0581 0.0609
Echinococcus multilocularis proteasome subunit beta type 6 0.0248 0.1433 0.1433
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1261 0.7856 1
Schistosoma mansoni hypothetical protein 0.0452 0.273 0.286
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.1261 0.7856 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Loa Loa (eye worm) hypothetical protein 0.0081 0.0379 0.0471
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0116 0.0145
Echinococcus multilocularis ubiquitin specific protease 41 0.0052 0.0192 0.0192
Trypanosoma brucei protein kinase, putative 0.0036 0.0093 0.0116
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0248 0.1433 0.1823
Brugia malayi Cyclin, N-terminal domain containing protein 0.0051 0.0188 0.0237
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0191 0.1076 0.136
Loa Loa (eye worm) hypothetical protein 0.0112 0.0574 0.0719
Schistosoma mansoni cyclin B 0.0051 0.0188 0.0197
Leishmania major pyruvate kinase 0.0033 0.0073 0.005
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0042 0.0129 0.0161
Mycobacterium leprae 3-dehydroquinate dehydratase AroD (AroQ) (3-dehydroquinase) (Type II DHQase) 0.1162 0.7227 0.9193
Echinococcus multilocularis C type lectin domian containing protein 0.0067 0.0288 0.0288
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0036 0.0093 0.0116
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0121 0.0112
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Brugia malayi ecdysteroid receptor 0.0137 0.0734 0.0932
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Trypanosoma cruzi cyclin, putative 0.0051 0.0188 0.0237
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0042 0.0129 0.0085
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Brugia malayi proteasome subunit alpha type 2 0.0248 0.1433 0.1823
Echinococcus granulosus somatostatin receptor 0.0071 0.0315 0.0378
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0274 0.0396
Schistosoma mansoni cpg binding protein 0.0063 0.0263 0.0275
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0032 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0071 0.0315 0.033
Echinococcus multilocularis neuropeptide Y receptor 0.0071 0.0315 0.0315
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0296 0.031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0155 0.0119
Echinococcus granulosus sex peptide receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis histone lysine n methyltransferase setd8 0.0078 0.0358 0.0358
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0133 0.0167
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0071 0.0315 0.0315
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.0639 0.0639
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Echinococcus multilocularis cathepsin L cysteine protease 0.0043 0.0133 0.0133
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0167 0.021
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.1348 0.1706
Loa Loa (eye worm) hypothetical protein 0.0052 0.0192 0.0232
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0082 0.0024
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Schistosoma mansoni jumonji domain containing protein 0.0101 0.0503 0.0527
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0231 0.1326 0.1621
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0137 0.0734 0.0923
Loa Loa (eye worm) cysteine protease 0.0043 0.0133 0.0157
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0071 0.0315 0.033
Echinococcus granulosus tm gpcr rhodopsin 0.0071 0.0315 0.0378
Echinococcus granulosus integrin alpha 3 0.0114 0.0583 0.07
Schistosoma mansoni hypothetical protein 0.0113 0.0581 0.0609
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0041 0.0125 0.015
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.019 0.1066 0.1355
Brugia malayi beta-lactamase 0.0079 0.0365 0.0462
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 1
Brugia malayi hypothetical protein 0.0065 0.0274 0.0346
Echinococcus granulosus orexin receptor type 2 0.0071 0.0315 0.0378
Loa Loa (eye worm) intermediate filament protein 0.013 0.0688 0.0865
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Loa Loa (eye worm) MBCTL1 0.0045 0.015 0.018
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0036 0.0093 0.0076
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.1433 0.1815
Leishmania major proteasome beta 7 subunit, putative 0.0248 0.1433 0.179
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Loa Loa (eye worm) fibroinase 0.0043 0.0133 0.0157
Loa Loa (eye worm) hypothetical protein 0.006 0.0246 0.0302
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Brugia malayi G protein-coupled receptor 0.0071 0.0315 0.0399
Brugia malayi Protein set-1 0.0078 0.0358 0.0453
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.098 0.6073 0.773
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0365 0.0462
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0036 0.0093 0.0106
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0073 0.0323 0.0338
Echinococcus granulosus tar DNA binding protein 0.0191 0.1076 0.1291
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Echinococcus granulosus cathepsin L 0.0022 0.0002 0.0002
Echinococcus granulosus lysosomal alpha glucosidase 0.0133 0.0705 0.0845
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0041 0.0125 0.0157
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0039 0.011 0.0137
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0042 0.0129 0.0085
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni neuropeptide F-like receptor 0.0071 0.0315 0.033
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.005
Schistosoma mansoni peptidase Clp (S14 family) 0.0056 0.0218 0.0228
Brugia malayi Steroid receptor seven-up type 2 0.0137 0.0734 0.0932
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Echinococcus multilocularis cysteine protease 0.0043 0.0133 0.0133
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0121 0.0145
Onchocerca volvulus 0.0043 0.0133 0.0153
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0064 0.0268 0.0281
Echinococcus multilocularis orexin receptor type 2 0.0071 0.0315 0.0315
Onchocerca volvulus 0.0039 0.011 0.0114
Echinococcus multilocularis GPCR, family 2 0.0041 0.0125 0.0125
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0052 0.0192 0.0242
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0155 0.0106
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Echinococcus multilocularis fmrfamide receptor 0.0071 0.0315 0.0315
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0063 0.0078
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0248 0.1433 0.1823
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0073 0.0323 0.0338
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0101 0.0503 0.0603
Loa Loa (eye worm) proteasome subunit beta type 1 0.098 0.6073 0.7728
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0245 0.0234
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0073 0.009
Echinococcus granulosus tumor protein p63 0.0213 0.1213 0.1455
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni integrin alpha 0.0148 0.0803 0.0841
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0137 0.0734 0.088
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0596 0.3642 0.3642
Trichomonas vaginalis cyclins, putative 0.0027 0.0034 0.0041
Giardia lamblia Pyruvate kinase 0.0033 0.0073 0.0013
Onchocerca volvulus 0.0079 0.0365 0.0553
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Onchocerca volvulus 0.0043 0.0133 0.0153
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0596 0.3642 0.4635
Echinococcus multilocularis musashi 0.013 0.0688 0.0688
Schistosoma mansoni biogenic amine receptor 0.0071 0.0315 0.033
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) PAS-3 protein 0.0248 0.1433 0.1815
Brugia malayi nuclear hormone receptor 0.0065 0.0274 0.0346
Schistosoma mansoni opsin-like receptor 0.0071 0.0315 0.033
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0248 0.1433 0.1807
Plasmodium vivax hypothetical protein, conserved 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.001 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0248 0.1433 0.1807
Toxoplasma gondii microneme protein MIC2 0.0039 0.011 0.0118
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0034 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0323 0.0409
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.005 0.0061
Onchocerca volvulus 0.0043 0.0133 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Trypanosoma cruzi hypothetical protein, conserved 0.0417 0.2505 0.3187
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0093 0.0116
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0133 0.0167
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0248 0.1433 0.1823
Schistosoma mansoni hypothetical protein 0.0039 0.011 0.0115
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0128 0.0673 0.0845
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0596 0.3642 0.4369
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0248 0.1433 0.1815
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1261 0.7856 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0031
Loa Loa (eye worm) hypothetical protein 0.0081 0.0379 0.0471
Toxoplasma gondii proteasome subunit alpha1, putative 0.0248 0.1433 0.1807
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0091 0.0439 0.0557
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0167 0.0134
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Plasmodium vivax acyl-CoA synthetase, putative 0.0034 0.0082 0.0101
Echinococcus granulosus histone lysine methyltransferase setb 0.0122 0.0639 0.0767
Giardia lamblia Furin precursor putative serine protease 0.019 0.1066 0.1287
Schistosoma mansoni biogenic amine receptor 0.0071 0.0315 0.033
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.011 0.0137
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0039 0.011 0.011
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0034 0.004
Schistosoma mansoni neuropeptide receptor 0.0071 0.0315 0.033
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Mycobacterium ulcerans hypothetical protein 0.0048 0.0167 0.0134
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0034 0.004
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0078
Loa Loa (eye worm) hypothetical protein 0.0051 0.0188 0.0228
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Onchocerca volvulus 0.0067 0.0288 0.0421
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0248 0.1433 0.1815
Echinococcus granulosus neuropeptide s receptor 0.036 0.2142 0.2569
Plasmodium vivax proteasome subunit beta type-3, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0073 0.0013
Echinococcus multilocularis citrate lyase subunit beta protein 0.0048 0.0167 0.0167
Echinococcus granulosus alpha 1A adrenergic receptor 0.0071 0.0315 0.0378
Brugia malayi proteasome subunit alpha type 6 0.0248 0.1433 0.1823
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0042 0.0129 0.0085
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0055 0.0066
Echinococcus multilocularis neuropeptide receptor 0.0575 0.351 0.351
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0051 0.0188 0.0197
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Onchocerca volvulus 0.006 0.0241 0.034
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0137 0.0734 0.0932
Leishmania major pyruvate kinase 0.0033 0.0073 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0063 0.0261 0.0261
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) subtilase 0.0042 0.0129 0.0152
Echinococcus granulosus g protein coupled receptor 0.0071 0.0315 0.0378
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0248 0.1433 0.1502
Echinococcus multilocularis microtubule associated protein 2 0.1337 0.8338 0.8338
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0034 0.0034
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.011 0.0137
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0039 0.011 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0137 0.0734 0.0932
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0607 0.3711 0.3887
Brugia malayi Pre-SET motif family protein 0.0832 0.5133 0.6534
Brugia malayi Integrin alpha pat-2 precursor 0.0148 0.0803 0.102
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0208 0.1179 0.1432
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0137 0.0734 0.088
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.004 0.0116 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Echinococcus granulosus allatostatin A receptor 0.0071 0.0315 0.0378
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0137 0.0734 0.088
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0137 0.0734 0.0769
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0067 0.0289 0.0346
Giardia lamblia G2/mitotic-specific cyclin B 0.0051 0.0188 0.0161
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0365 0.0388
Trypanosoma brucei proteasome beta 6 subunit 0.098 0.6073 0.773
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Echinococcus granulosus phd:f box containing protein 0.0027 0.0034 0.004
Onchocerca volvulus 0.0039 0.011 0.0114
Plasmodium vivax subtilisin-like serine protease, putative 0.0042 0.0129 0.0161
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0067 0.0288 0.0356
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0248 0.1433 0.1823
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.004 0.0116 0.0124
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0063
Schistosoma mansoni neuropeptide F-like receptor 0.0071 0.0315 0.033
Plasmodium vivax proteasome subunit beta type-5, putative 0.1261 0.7856 1
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0073 0.0013
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0248 0.1433 0.1823
Brugia malayi Will die slowly protein 0.0283 0.1657 0.2107
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0071 0.0315 0.033
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0248 0.1433 0.1502
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0365 0.0388
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0165 0.091 0.091
Onchocerca volvulus 0.013 0.0688 0.1108
Mycobacterium tuberculosis Conserved protein 0.0079 0.0365 0.0388
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0034 0.004
Brugia malayi jmjC domain containing protein 0.0104 0.0525 0.0665
Echinococcus multilocularis g protein coupled receptor 0.0071 0.0315 0.0315
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0245 0.0234
Mycobacterium tuberculosis 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 0.1162 0.7227 0.9194
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0063 0.0078
Loa Loa (eye worm) RNA binding protein 0.0191 0.1076 0.136
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Brugia malayi Intermediate filament tail domain containing protein 0.013 0.0688 0.0873
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Echinococcus multilocularis cyclin B3 1 0.0032 0.0066 0.0066
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0071 0.0315 0.033
Onchocerca volvulus 0.0071 0.0315 0.0467
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0248 0.1433 0.1807
Onchocerca volvulus 0.0077 0.035 0.0526
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0063 0.0078
Loa Loa (eye worm) hypothetical protein 0.0035 0.0082 0.0093
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0071 0.0315 0.039
Echinococcus granulosus biogenic amine 5HT receptor 0.0071 0.0315 0.0378
Echinococcus granulosus proteasome subunit alpha type 2 0.0248 0.1433 0.1719
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0315
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0137 0.0734 0.0734
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0052 0.0192 0.0192
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Plasmodium vivax SET domain protein, putative 0.0122 0.0639 0.0811
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0023 0.0024
Brugia malayi nuclear hormone receptor family member odr-7 0.0065 0.0274 0.0346
Schistosoma mansoni cpg binding protein 0.0063 0.0263 0.0275
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0034 0.0035
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0248 0.1433 0.1823
Echinococcus granulosus proteasome subunit alpha type 6 0.0248 0.1433 0.1719
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0137 0.0734 0.0932
Giardia lamblia Proteasome subunit beta type 5 precursor 0.1261 0.7856 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.005 0.0061
Echinococcus multilocularis neuropeptide s receptor 0.036 0.2142 0.2142
Trypanosoma cruzi 20S proteasome subunit 0.0607 0.3711 0.4722
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.006 0.0246 0.0302
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis cyclin B3, putative 0.0032 0.0066 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus granulosus 7TM GPCR rhodopsin 0.0071 0.0315 0.0378
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) DR-78 0.0065 0.0274 0.0337
Echinococcus multilocularis pyruvate kinase 0.0026 0.0029 0.0029
Echinococcus multilocularis serotonin receptor 0.0071 0.0315 0.0315
Brugia malayi follicle stimulating hormone receptor 0.0547 0.3328 0.4235
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0063 0.0078
Echinococcus multilocularis calpain A 0.0067 0.0289 0.0289
Schistosoma mansoni adenoreceptor 0.0071 0.0315 0.033
Echinococcus granulosus hypothetical protein 0.0071 0.0315 0.0378
Toxoplasma gondii subtilisin SUB7 0.0042 0.0129 0.0142
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis proteasome (prosome, macropain) 0.1261 0.7856 0.7856
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0274 0.0328
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0131 0.0692 0.0879
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0022 0.0025
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0052 0.0192 0.0242
Echinococcus multilocularis g protein coupled receptor 0.0071 0.0315 0.0315
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0734 0.0769
Echinococcus granulosus ecdysone induced protein 78C 0.0137 0.0734 0.088
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.004 0.0116 0.0136
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0063 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0044 0.0053
Brugia malayi MH2 domain containing protein 0.0234 0.1348 0.1714
Loa Loa (eye worm) neuropeptide F receptor 0.0071 0.0315 0.039
Echinococcus granulosus citrate lyase subunit beta protein 0.0048 0.0167 0.0201
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Brugia malayi sulfakinin receptor protein 0.0071 0.0315 0.0399
Schistosoma mansoni cpg binding protein 0.006 0.0241 0.0253
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0036 0.0093 0.0116
Brugia malayi mbt repeat family protein 0.004 0.0116 0.0145
Echinococcus granulosus Furin 1 0.0232 0.1332 0.1597
Trypanosoma cruzi cysteine peptidase, putative 0.0162 0.0891 0.1132
Brugia malayi Zona pellucida-like domain containing protein 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trypanosoma cruzi cysteine peptidase, putative 0.0162 0.0891 0.1132
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0071 0.0315 0.033
Echinococcus granulosus biogenic amine 5HT receptor 0.0071 0.0315 0.0378
Schistosoma mansoni hypothetical protein 0.0032 0.0065 0.0068
Leishmania major proteasome alpha 1 subunit, putative 0.0248 0.1433 0.179
Echinococcus multilocularis c4b binding protein beta chain 0.0067 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0385 0.2302 0.2922
Onchocerca volvulus 0.0067 0.0288 0.0421
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0047 0.0057
Onchocerca volvulus 0.0071 0.0315 0.0467
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0481 0.0572
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0073 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.005 0.0061
Brugia malayi G protein-coupled receptor F59B2.13 0.0071 0.0315 0.0399
Mycobacterium ulcerans hypothetical protein 0.0079 0.0365 0.0388
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0046 0.0155 0.0192
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Leishmania major hypothetical protein, conserved 0.0079 0.0365 0.0424
Echinococcus granulosus 7tm_1 domain containing protein 0.0071 0.0315 0.0378
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0116 0.0601 0.069
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0034 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0137 0.0734 0.0923
Brugia malayi RNA binding protein 0.0191 0.1076 0.1368
Echinococcus granulosus dnaJ subfamily B 0.0555 0.3381 0.4055
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0137 0.0734 0.0769
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0037 0.0096 0.0029
Trichomonas vaginalis esterase, putative 0.0079 0.0365 0.0462
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Echinococcus multilocularis allatostatin A receptor 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Leishmania major subtilisin-like serine peptidase 0.0042 0.0129 0.0122
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0081
Schistosoma mansoni cathepsin F (C01 family) 0.0043 0.0133 0.0139
Loa Loa (eye worm) hypothetical protein 0.0045 0.015 0.018
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0155 0.0119
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Plasmodium vivax proteasome subunit beta type-7, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi larval opioid receptor 0.0071 0.0315 0.0399
Schistosoma mansoni coup transcription factor 0.0137 0.0734 0.0769
Schistosoma mansoni hypothetical protein 0.025 0.145 0.1519
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0365 0.0388
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0274 0.0328
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0034 0.0082 0.0024
Echinococcus granulosus C type lectin domian containing protein 0.0067 0.0288 0.0346
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0045 0.015 0.0189
Onchocerca volvulus 0.0071 0.0315 0.0467
Schistosoma mansoni intermediate filament proteins 0.013 0.0688 0.072
Plasmodium vivax apical sushi protein, putative 0.0067 0.0288 0.0365
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0121 0.0444
Trypanosoma cruzi hypothetical protein, conserved 0.0417 0.2505 0.3187
Toxoplasma gondii ABC1 family protein 0.0079 0.0365 0.0444
Giardia lamblia Cyclin A 0.0032 0.0066 0.0004
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0607 0.3711 0.4722
Echinococcus granulosus collagen alpha 1VII chain 0.0039 0.011 0.0132
Brugia malayi endoprotease bli-4 precursor 0.0981 0.6082 0.7741
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0248 0.1433 0.1759
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0365 0.0388
Trypanosoma cruzi trypanothione reductase, putative 0.0091 0.044 0.0558
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0248 0.1433 0.1815
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Leishmania major cysteine peptidase A (CPA) 0.0043 0.0133 0.0127
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Schistosoma mansoni neuropeptide receptor 0.0071 0.0315 0.033
Echinococcus granulosus histone lysine n methyltransferase setd8 0.0078 0.0358 0.0429
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0041 0.0125 0.015
Echinococcus multilocularis neutral alpha glucosidase AB 0.0029 0.005 0.005
Trichomonas vaginalis WD repeat domain, putative 0.0283 0.1657 0.2107
Brugia malayi nuclear hormone receptor 0.0137 0.0734 0.0932
Plasmodium falciparum proteasome subunit beta type-5 0.1261 0.7856 1
Onchocerca volvulus 0.0039 0.011 0.0114
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0042 0.0129 0.0085
Onchocerca volvulus Notchless protein homolog 0.0248 0.1433 0.239
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0034 0.0035
Brugia malayi calpain family protein 1 0.0064 0.0268 0.0339
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0081
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0065 0.0274 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Plasmodium falciparum subtilisin-like protease 1 0.0042 0.0129 0.0161
Brugia malayi Glycosyl hydrolases family 31 protein 0.0133 0.0705 0.0895
Echinococcus multilocularis calpain family protein 1, d 0.0045 0.0148 0.0148
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0274 0.0346
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0063 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0192 0.0242
Plasmodium falciparum pyruvate kinase 0.0033 0.0073 0.009
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0155 0.0119
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0256 0.1483 0.1553
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0073 0.009
Onchocerca volvulus 0.0283 0.1657 0.2774
Loa Loa (eye worm) thioredoxin reductase 0.0091 0.044 0.0549
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0056 0.0218 0.0275
Brugia malayi Proteasome A-type and B-type family protein 0.1261 0.7856 1
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0248 0.1433 0.1433
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0248 0.1433 0.1433
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0052 0.0192 0.023
Chlamydia trachomatis pyruvate kinase 0.0033 0.0073 0.0637
Entamoeba histolytica proteasome subunit beta type 1, putative 0.098 0.6073 0.773
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.011 0.0137
Trypanosoma cruzi cruzipain precursor, putative 0.0162 0.0891 0.1132
Echinococcus granulosus calpain A 0.0067 0.0289 0.0346
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0056 0.0218 0.0256
Onchocerca volvulus 0.0043 0.0133 0.0153
Schistosoma mansoni myelin transcription factor 1 myt1 0.0045 0.015 0.0158
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0034 0.004
Loa Loa (eye worm) nuclear receptor NHR-67 0.0065 0.0274 0.0337
Giardia lamblia Proteasome subunit beta type 2 0.0607 0.3711 0.4681
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Brugia malayi Subtilase family protein 0.0042 0.0129 0.0161
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0121 0.0121
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0248 0.1433 0.1823
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0274 0.0328
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0365 0.0388
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Onchocerca volvulus 0.0079 0.0365 0.0553
Brugia malayi RNA recognition motif domain containing protein 0.0191 0.1076 0.1368
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0248 0.1433 0.1823
Echinococcus granulosus polycomb protein SCMH1 0.004 0.0116 0.0139
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0065 0.0274 0.0274
Brugia malayi pregnancy-associated plasma protein-A 0.0067 0.0288 0.0365
Mycobacterium ulcerans proteasome PrcA 0.0248 0.1433 0.1759
Onchocerca volvulus 0.0071 0.0315 0.0467
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.003 0.0052 0.0054
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0155 0.0106
Loa Loa (eye worm) mbt repeat family protein 0.004 0.0116 0.0135
Mycobacterium leprae proteasome (beta subunit) PrcB 0.1261 0.7856 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0029 0.0047 0.0057
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0167 0.0171
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0547 0.3328 0.423
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Leishmania major alpha glucosidase II subunit, putative 0.0029 0.005 0.0021
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Echinococcus granulosus lamin dm0 0.013 0.0688 0.0825
Echinococcus granulosus tm gpcr rhodopsin 0.0071 0.0315 0.0378
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Schistosoma mansoni integrin alpha-ps 0.0066 0.0284 0.0298
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0073 0.0323 0.0323
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0071 0.0315 0.0378
Echinococcus multilocularis ecdysone induced protein 78C 0.0137 0.0734 0.0734
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Brugia malayi AKH receptor 0.0071 0.0315 0.0399
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0137 0.0734 0.0932
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0231 0.1326 0.161
Echinococcus granulosus cyclin B 0.0051 0.0188 0.0226
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0067 0.0289 0.0303
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus granulosus tachykinin peptides receptor 99D 0.0071 0.0315 0.0378
Leishmania major proteasome alpha 1 subunit, putative 0.0248 0.1433 0.179
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0248 0.1433 0.1502
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0037
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0248 0.1433 0.1719
Onchocerca volvulus 0.0071 0.0315 0.0467
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0035 0.0087 0.0108
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0097 0.0481 0.061
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0208 0.1179 0.1432
Leishmania major proteasome alpha 7 subunit, putative 0.0248 0.1433 0.179
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0052 0.0192 0.0192
Echinococcus multilocularis integrin alpha ps 0.0032 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.019 0.1066 0.1117
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0116 0.0145
Schistosoma mansoni alpha glucosidase 0.0029 0.005 0.0052
Leishmania major cyclin 0.0051 0.0188 0.0197
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0101 0.0503 0.0503
Onchocerca volvulus 0.0071 0.0315 0.0467
Toxoplasma gondii subtilisin SUB6 0.0042 0.0129 0.0142
Onchocerca volvulus 0.0079 0.0365 0.0553
Loa Loa (eye worm) TYRA-2 protein 0.0071 0.0315 0.039
Echinococcus multilocularis polycomb protein SCMH1 0.004 0.0116 0.0116
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0248 0.1433 0.1759
Trypanosoma cruzi cyclin 6, putative 0.0051 0.0188 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Echinococcus granulosus G protein coupled receptor kinase 1 0.0098 0.0485 0.0582
Schistosoma mansoni nuclear hormone receptor 0.0137 0.0734 0.0769
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0278 0.1624 0.1701
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Toxoplasma gondii cathepsin CPL 0.0043 0.0133 0.0148
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0091 0.044 0.0484
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0365 0.0462
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Brugia malayi G-protein coupled receptor 0.0071 0.0315 0.0399
Echinococcus multilocularis pyruvate kinase 0.0033 0.0073 0.0073
Loa Loa (eye worm) jmjC domain-containing protein 0.0104 0.0525 0.0657
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0071 0.0315 0.033
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0365 0.0462
Schistosoma mansoni jumonji/arid domain-containing protein 0.0104 0.0525 0.0549
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Echinococcus multilocularis serotonin receptor 0.0071 0.0315 0.0315
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.004 0.0116 0.0105
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Toxoplasma gondii proteasome subunit beta type, putative 0.1261 0.7856 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Echinococcus granulosus g protein coupled receptor 0.0071 0.0315 0.0378
Schistosoma mansoni cyclins 0.0032 0.0066 0.0069
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0137 0.0734 0.0769
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0121 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0133 0.0705 0.0886
Mycobacterium leprae Probable lipase LipE 0.0079 0.0365 0.0376
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0071 0.0315 0.0399
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0042 0.0129 0.0085
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0274 0.0396
Echinococcus multilocularis neuropeptide receptor A26 0.036 0.2142 0.2142
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Loa Loa (eye worm) CUTiclin family member 0.0039 0.011 0.0128
Echinococcus granulosus g protein coupled receptor 0.0071 0.0315 0.0378
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0192 0.0242
Echinococcus granulosus cathepsin l1 0.0028 0.0044 0.0052
Plasmodium falciparum proteasome subunit beta type-1, putative 0.098 0.6073 0.773
Onchocerca volvulus 0.0042 0.0129 0.0146
Echinococcus multilocularis pyruvate kinase 0.0033 0.0073 0.0073
Echinococcus granulosus proteasome subunit beta t family 0.0248 0.1433 0.1719
Onchocerca volvulus Protein ultraspiracle homolog 0.0137 0.0734 0.1187
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0481 0.061
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus granulosus proteasome subunit beta type 6 0.0248 0.1433 0.1719
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.1183
Onchocerca volvulus 0.0039 0.011 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0296 0.031
Trypanosoma brucei hypothetical protein, conserved 0.0417 0.2505 0.3187
Echinococcus multilocularis lysine specific demethylase 5A 0.0101 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Toxoplasma gondii rhoptry neck protein RON1 0.0067 0.0288 0.0346
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0248 0.1433 0.1807
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0121 0.0075
Echinococcus multilocularis neuropeptides capa receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis somatostatin receptor 0.0071 0.0315 0.0315
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Loa Loa (eye worm) hypothetical protein 0.004 0.0116 0.0135
Loa Loa (eye worm) endoprotease bli-4 0.0981 0.6082 0.7739
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.005 0.0061
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0034 0.0035
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0248 0.1433 0.1433
Onchocerca volvulus Neuropeptide F receptor homolog 0.0071 0.0315 0.0467
Echinococcus multilocularis cpg binding protein 0.0063 0.0263 0.0263
Leishmania major hypothetical protein, conserved 0.0417 0.2505 0.3159
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0137 0.0734 0.088
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1261 0.7856 1
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0365 0.0388
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0029 0.005 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0557 0.0583
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0365 0.0383
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0065
Brugia malayi neuropeptide F receptor 0.0071 0.0315 0.0399
Echinococcus multilocularis survival motor neuron protein 1 0.0446 0.2688 0.2688
Loa Loa (eye worm) hypothetical protein 0.0082 0.0381 0.0474
Brugia malayi Calcitonin receptor-like protein seb-1 0.0131 0.0692 0.0879
Echinococcus multilocularis FTZ F1 alpha 0.0137 0.0734 0.0734
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0248 0.1433 0.1823
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Conserved protein 0.0079 0.0365 0.0388
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0639 0.067
Onchocerca volvulus 0.0071 0.0315 0.0467
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Brugia malayi mbt repeat family protein 0.004 0.0116 0.0145
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0133 0.0167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0365 0.0388
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0052 0.0192 0.0165
Schistosoma mansoni neuropeptide receptor 0.0575 0.351 0.3677
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0063 0.0058
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0071 0.0315 0.039
Brugia malayi Cathepsin L-like cysteine proteinase 0.0028 0.0044 0.0053
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0248 0.1433 0.1823
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0274 0.0346
Echinococcus multilocularis beta adrenergic receptor kinase 0.0109 0.0557 0.0557
Mycobacterium ulcerans hypothetical protein 0.0046 0.0155 0.0119
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.098 0.6073 0.773
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0045 0.015 0.018
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0039 0.011 0.0137
Echinococcus multilocularis mitogen activated protein kinase 0.0036 0.0093 0.0093
Entamoeba histolytica cysteine protease, putative 0.0043 0.0133 0.0167
Echinococcus granulosus integrin alpha ps 0.0032 0.0065 0.0078
Trichomonas vaginalis cyclin B, putative 0.0032 0.0066 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0041 0.0125 0.0125
Echinococcus granulosus serotonin receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Mycobacterium ulcerans hypothetical protein 0.0108 0.0551 0.0626
Onchocerca volvulus 0.0067 0.0288 0.0421
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0043 0.0133 0.0167
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.1433 0.1823
Trypanosoma brucei proteasome beta 7 subunit 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0275
Brugia malayi proteasome subunit alpha type 1 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0023 0.0024
Brugia malayi jmjC domain containing protein 0.0101 0.0503 0.0638
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0071 0.0315 0.0467
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Brugia malayi Nuclear hormone receptor-like 1 0.0137 0.0734 0.0932
Echinococcus granulosus neuropeptides capa receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.019 0.1066 0.1355
Onchocerca volvulus Cathepsin L homolog 0.0043 0.0133 0.0153
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi conserved hypotetical protein 0.0065 0.0274 0.0346
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0248 0.1433 0.1719
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Toxoplasma gondii hypothetical protein 0.0033 0.0074 0.0072
Echinococcus granulosus pyruvate kinase 0.0033 0.0073 0.0087
Echinococcus multilocularis protein will die slowly 0.0283 0.1657 0.1657
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0137 0.0734 0.0734
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.1433 0.1823
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0245 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni lamin 0.013 0.0688 0.072
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0323 0.0409
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0274 0.0274
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0245 0.0257
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0155 0.0156
Onchocerca volvulus 0.0091 0.0439 0.068
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Onchocerca volvulus 0.0067 0.0288 0.0421
Plasmodium falciparum cysteine proteinase falcipain 3 0.0043 0.0133 0.0167
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0596 0.3642 0.4635
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.0044 0.0046
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0167 0.021
Onchocerca volvulus 0.0067 0.0288 0.0421
Brugia malayi Dopamine receptor protein 2 0.0071 0.0315 0.0399
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Schistosoma mansoni alpha-glucosidase 0.0114 0.0587 0.0615
Toxoplasma gondii subtilisin SUB10 0.0042 0.0129 0.0142
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0043 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0046 0.0155 0.0186
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Loa Loa (eye worm) melatonin receptor type 1A 0.0071 0.0315 0.039
Echinococcus granulosus Proteasome subunit alpha beta 0.0248 0.1433 0.1719
Echinococcus granulosus lamin 0.013 0.0688 0.0825
Onchocerca volvulus 0.0065 0.0274 0.0396
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0248 0.1433 0.1807
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0248 0.1433 0.1502
Onchocerca volvulus 0.015 0.0813 0.1324
Brugia malayi cathepsin L-like precursor 0.0028 0.0044 0.0053
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.007 0.0305 0.0377
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0378
Echinococcus granulosus mitogen activated protein kinase 3 0.0036 0.0093 0.0111
Giardia lamblia Fructose-bisphosphate aldolase 0.0238 0.1373 0.1681
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0176
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Loa Loa (eye worm) hypothetical protein 0.0064 0.0268 0.033
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Toxoplasma gondii proteasome subunit alpha type, putative 0.0248 0.1433 0.1807
Mycobacterium tuberculosis Conserved protein 0.0079 0.0365 0.0388
Onchocerca volvulus 0.0071 0.0315 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0093 0.0097
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0073 0.009
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0248 0.1433 0.1823
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis integrin alpha ps 0.0066 0.0284 0.0284
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Schistosoma mansoni hypothetical protein 0.0283 0.1657 0.1735
Echinococcus granulosus cathepsin L cysteine proteinase 0.0043 0.0133 0.0159
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0043 0.0133 0.0133
Brugia malayi Thioredoxin reductase 0.0091 0.044 0.0558
Toxoplasma gondii subtilisin SUB12 0.0042 0.0129 0.0142
Brugia malayi hypothetical protein 0.0446 0.2688 0.342
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Loa Loa (eye worm) histone methyltransferase 0.0025 0.0023 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni lamin 0.013 0.0688 0.072
Onchocerca volvulus 0.0946 0.5858 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0116 0.0145
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0248 0.1433 0.1433
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0036 0.0093 0.0096
Trypanosoma cruzi cysteine peptidase, putative 0.0162 0.0891 0.1132
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0071 0.0315 0.033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0121 0.0152
Echinococcus multilocularis integrin alpha ps 0.0066 0.0284 0.0284
Loa Loa (eye worm) glutathione reductase 0.0091 0.044 0.0549
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.1433 0.1823
Schistosoma mansoni cathepsin F (C01 family) 0.0043 0.0133 0.0139
Schistosoma mansoni myosin xvIII 0.0071 0.0315 0.033
Echinococcus multilocularis histone acetyltransferase MYST2 0.0045 0.015 0.015
Brugia malayi Dopamine receptor protein 1 0.0071 0.0315 0.0399
Brugia malayi tailless protein 0.0065 0.0274 0.0346
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0199
Brugia malayi Cyclin, N-terminal domain containing protein 0.0032 0.0066 0.0082
Mycobacterium ulcerans hypothetical protein 0.0048 0.0167 0.0134
Schistosoma mansoni alpha-glucosidase 0.0114 0.0587 0.0615
Schistosoma mansoni zinc finger protein 0.0065 0.0274 0.0287
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0043 0.0133 0.0157
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0137 0.0734 0.0923
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0155 0.0195
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0029 0.005 0.0042
Brugia malayi beta-lactamase family protein 0.0079 0.0365 0.0462
Giardia lamblia 20S proteasome alpha subunit 2 0.0248 0.1433 0.1759
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Echinococcus granulosus microtubule associated protein 2 0.1337 0.8338 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Mycobacterium tuberculosis Conserved protein 0.0048 0.0167 0.0134
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.1433 0.1815
Toxoplasma gondii proteasome subunit beta type 1, putative 0.098 0.6073 0.7725
Trypanosoma brucei glucosidase, putative 0.0029 0.005 0.0061
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.013 0.0688 0.0865
Giardia lamblia High cysteine membrane protein Group 2 0.0365 0.2174 0.2709
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0137 0.0734 0.088
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0052 0.0192 0.0201
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Brugia malayi hypothetical protein 0.0073 0.0323 0.0409
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0137 0.0734 0.0769
Brugia malayi ecdysone receptor 0.0065 0.0274 0.0346
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0071 0.0315 0.0315
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0065 0.0274 0.0328
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0071 0.0315 0.039
Echinococcus granulosus neuropeptide Y receptor 0.0071 0.0315 0.0378
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0248 0.1433 0.1823
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0071 0.0315 0.033
Echinococcus multilocularis SAM and MBT domain containing protein 0.004 0.0116 0.0116
Trichomonas vaginalis set domain proteins, putative 0.0946 0.5858 0.7457
Toxoplasma gondii exonuclease III APE 0.0041 0.0121 0.0132
Echinococcus granulosus cpg binding protein 0.0063 0.0263 0.0315
Plasmodium falciparum cyclin 0.0032 0.0066 0.0082
Plasmodium falciparum thrombospondin-related anonymous protein 0.0039 0.011 0.0137
Plasmodium vivax vivapain-2 0.0043 0.0133 0.0167
Giardia lamblia 20S proteasome alpha subunit 3 0.0248 0.1433 0.1759
Brugia malayi RE15519p 0.0071 0.0315 0.0399
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0248 0.1433 0.1815
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Schistosoma mansoni biogenic amine receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0137 0.0734 0.0923
Leishmania major proteasome alpha 3 subunit, putative 0.0248 0.1433 0.179
Echinococcus multilocularis lamin dm0 0.013 0.0688 0.0688
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.001 0.001
Onchocerca volvulus 0.0043 0.0133 0.0153
Schistosoma mansoni ap endonuclease 0.0041 0.0121 0.0127
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0137 0.0734 0.0734
Plasmodium falciparum thioredoxin reductase 0.0091 0.044 0.0558
Onchocerca volvulus 0.0067 0.0288 0.0421
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0365 0.0388
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Leishmania major proteasome beta 5 subunit, putative 0.1261 0.7856 1
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.023 0.1321 0.1384
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0248 0.1433 0.1502
Brugia malayi GnHR receptor homolog 0.0071 0.0315 0.0399
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0155 0.0195
Echinococcus granulosus FTZ F1 alpha 0.0137 0.0734 0.088
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0248 0.1433 0.1823
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0248 0.1433 0.1823
Schistosoma mansoni hypothetical protein 0.0089 0.043 0.045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0031
Onchocerca volvulus 0.0043 0.0133 0.0153
Onchocerca volvulus Cathepsin L homolog 0.0043 0.0133 0.0153
Plasmodium vivax subtilisin-like protease 2, putative 0.0042 0.0129 0.0161
Plasmodium vivax glutathione reductase, putative 0.0091 0.044 0.0558
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0365 0.0462
Plasmodium vivax proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.005 0.0061
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0137 0.0734 0.0734
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0137 0.0734 0.0932
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0034 0.004
Loa Loa (eye worm) proteasome subunit beta type 3 0.0248 0.1433 0.1815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni biogenic amine (5HT) receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0137 0.0734 0.0923
Brugia malayi steroid hormone receptor 0.0137 0.0734 0.0932
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0248 0.1433 0.1433
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Giardia lamblia Hypothetical protein 0.0032 0.0066 0.0004
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.004 0.0116 0.0139
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0981 0.6082 0.6371
Trichomonas vaginalis cyclins, putative 0.0032 0.0066 0.0082
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0022 0.0002 0.0002
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0231 0.1326 0.1621
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0315
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0065 0.0274 0.0337
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Echinococcus granulosus neuropeptide Y receptor 0.0071 0.0315 0.0378
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0121 0.0152
Onchocerca volvulus 0.0039 0.011 0.0114
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0121 0.0152
Echinococcus granulosus geminin 0.0452 0.273 0.3274
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi Proteasome subunit alpha type 7-1 0.0248 0.1433 0.1823
Plasmodium vivax vivapain-2 0.0043 0.0133 0.0167
Schistosoma mansoni nuclear receptor nhr-48 0.0065 0.0274 0.0287
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0137 0.0734 0.0923
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0063 0.0078
Loa Loa (eye worm) steroid hormone receptor 0.0137 0.0734 0.0923
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0073 0.009
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0052 0.0192 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Mycobacterium tuberculosis Probable reductase 0.0208 0.1179 0.1432
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0122 0.0639 0.0803
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.005 0.0061
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0248 0.1433 0.1823
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0022 0.0002 0.0002
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0192 0.0242
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0639 0.067
Plasmodium vivax proteasome subunit beta type-6, putative 0.0248 0.1433 0.1823
Brugia malayi celfurPC protein 0.0791 0.4879 0.621
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0081
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0607 0.3711 0.4722
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0068 0.0296 0.0375
Toxoplasma gondii rhoptry neck protein RON9 0.0067 0.0288 0.0346
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Brugia malayi Cyclin, N-terminal domain containing protein 0.0051 0.0188 0.0237
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0365 0.0365
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0078
Brugia malayi Pre-SET motif family protein 0.0122 0.0639 0.0811
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Onchocerca volvulus 0.0067 0.0288 0.0421
Schistosoma mansoni neuropeptide receptor 0.0071 0.0315 0.033
Echinococcus granulosus Proteasome subunit alpha type 7 0.0248 0.1433 0.1719
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0137 0.0734 0.088
Trypanosoma cruzi subtilisin peptidase 0.0042 0.0129 0.0161
Giardia lamblia 20S proteasome alpha subunit 4 0.0248 0.1433 0.1759
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0248 0.1433 0.1502
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0116 0.0121
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0073 0.0323 0.04
Echinococcus granulosus tm gpcr rhodopsin 0.0071 0.0315 0.0378
Echinococcus granulosus ubiquitin specific protease 41 0.0052 0.0192 0.023
Echinococcus granulosus neuropeptides capa receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trypanosoma brucei subtilisin peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0734 0.0769
Schistosoma mansoni alpha-1 adrenergic receptor 0.0071 0.0315 0.033
Brugia malayi Melatonin receptor type 1A 0.0071 0.0315 0.0399
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.005 0.0061
Onchocerca volvulus Cathepsin F homolog 0.0043 0.0133 0.0153
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Schistosoma mansoni neuropeptide f receptor 76f 0.0071 0.0315 0.033
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0365 0.0388
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0039 0.011 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0137 0.0734 0.0932
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0048 0.0167 0.0134
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0071 0.0315 0.033
Brugia malayi latrophilin 2 splice variant baaae 0.0089 0.043 0.0545
Trypanosoma cruzi cysteine peptidase, putative 0.0043 0.0133 0.0167
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni jumonji/arid domain-containing protein 0.0104 0.0525 0.0549
Brugia malayi Probable ClpP-like protease 0.0056 0.0218 0.0275
Echinococcus multilocularis tumor protein p63 0.0213 0.1213 0.1213
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0121 0.0075
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0121 0.0424
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0137 0.0734 0.0932
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0071 0.0315 0.0399
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0155 0.0195
Echinococcus multilocularis lysosomal alpha glucosidase 0.0133 0.0705 0.0705
Schistosoma mansoni growth hormone secretagogue receptor 0.0071 0.0315 0.033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.1131
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0116 0.0601 0.069
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0378
Treponema pallidum fructose-bisphosphate aldolase 0.0238 0.1373 1
Brugia malayi nuclear receptor NHR-67 0.0065 0.0274 0.0346
Echinococcus multilocularis lamin 0.013 0.0688 0.0688
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Schistosoma mansoni ap endonuclease 0.0041 0.0121 0.0127
Brugia malayi calpain family protein 1 0.0064 0.0268 0.0339
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.005
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0039 0.011 0.0128
Leishmania major mitochondrial DNA polymerase beta 0.0206 0.1168 0.1451
Schistosoma mansoni furin-1 (S08 family) 0.0427 0.2568 0.269
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.1433 0.1815
Brugia malayi G-protein coupled receptor 0.0071 0.0315 0.0399
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable oxidoreductase 0.0231 0.1326 0.1621
Brugia malayi nuclear receptor NHR-88 0.0065 0.0274 0.0346
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0248 0.1433 0.1823
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0042 0.0129 0.0161
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0039 0.011 0.0118
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Brugia malayi hypothetical protein 0.0073 0.0323 0.0409
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.019 0.1066 0.1355
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0048 0.0167 0.0134
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0071 0.0315 0.0315
Toxoplasma gondii peptidase, T1 family protein 0.0248 0.1433 0.1807
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.098 0.6073 0.773
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0042 0.0129 0.0154
Echinococcus granulosus lysine specific demethylase 5A 0.0104 0.0525 0.0629
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Entamoeba histolytica cyclin, putative 0.0051 0.0188 0.0237
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Echinococcus granulosus protein will die slowly 0.0283 0.1657 0.1987
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0137 0.0734 0.1187
Trypanosoma cruzi cyclin, putative 0.0051 0.0188 0.0237
Echinococcus granulosus neuropeptide receptor A26 0.036 0.2142 0.2569
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0114 0.0588 0.0705
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0052 0.0192 0.023
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0034 0.0082 0.12
Leishmania major proteasome beta 3 subunit, putative 0.0248 0.1433 0.179
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0039 0.011 0.0115
Loa Loa (eye worm) TAR-binding protein 0.0191 0.1076 0.136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0248 0.1433 0.1719
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0071 0.0315 0.0378
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Leishmania major proteasome alpha 2 subunit, putative 0.0248 0.1433 0.179
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0034 0.0031
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0248 0.1433 0.1433
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0041 0.0125 0.0148
Brugia malayi GCC2 and GCC3 family protein 0.0067 0.0288 0.0365
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0109 0.0557 0.0698
Trypanosoma brucei trypanothione reductase 0.0091 0.044 0.0558
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0042 0.0129 0.0161
Echinococcus granulosus thyroid hormone receptor alpha 0.0065 0.0274 0.0328
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0248 0.1433 0.1502
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Echinococcus granulosus nuclear receptor nhr 48 0.0065 0.0274 0.0328
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0155 0.0119
Schistosoma mansoni hypothetical protein 0.0039 0.011 0.0115
Brugia malayi hypothetical protein 0.0113 0.0581 0.0738
Brugia malayi hypothetical protein 0.015 0.0813 0.1033
Echinococcus multilocularis peptidase Clp (S14 family) 0.0037 0.0096 0.0096
Echinococcus granulosus neuropeptide FF receptor 2 0.0071 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.013 0.0688 0.0865
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0248 0.1433 0.179
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0248 0.1433 0.1433
Giardia lamblia Kinase, CMGC MAPK 0.0036 0.0093 0.0038
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0032 0.0066 0.0079
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.0133 0.0157
Echinococcus granulosus subfamily T1A non peptidase ue 0.0248 0.1433 0.1719
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0044 0.0053
Echinococcus granulosus cathepsin l1 0.0043 0.0133 0.0159
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0248 0.1433 0.1823
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Plasmodium vivax subtilisin-like protease 1 0.0042 0.0129 0.0161
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0148 0.0802 0.1019
Loa Loa (eye worm) integrin alpha pat-2 0.0229 0.1312 0.166
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0607 0.3711 0.445
Echinococcus multilocularis Furin 1 0.0232 0.1332 0.1332
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis mitogen activated protein kinase 3 0.0036 0.0093 0.0093
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0208 0.1179 0.1432
Loa Loa (eye worm) WD40 repeat protein 0.0283 0.1657 0.21
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0039 0.011 0.0137
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.1261 0.7856 0.8229
Echinococcus granulosus voltage dependent calcium channel subunit 0.0039 0.011 0.0132
Trichomonas vaginalis cyclin D, putative 0.0032 0.0066 0.0082
Echinococcus multilocularis tar DNA binding protein 0.0191 0.1076 0.1076
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0034 0.0035
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0121 0.0142
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0045 0.015 0.015
Brugia malayi proteasome subunit beta type 2 0.0607 0.3711 0.4722
Loa Loa (eye worm) hypothetical protein 0.0981 0.6082 0.7739
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0137 0.0734 0.0769
Brugia malayi Cathepsin L-like precursor 0.0028 0.0044 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0296 0.031
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus multilocularis integrin alpha 3 0.0114 0.0583 0.0583
Leishmania major proteasome alpha 7 subunit, putative 0.0248 0.1433 0.179
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0248 0.1433 0.1815
Loa Loa (eye worm) hypothetical protein 0.0063 0.0261 0.0321
Toxoplasma gondii heat shock protein hslv, putative 0.0248 0.1433 0.1807
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0034 0.004
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Trichomonas vaginalis hypothetical protein 0.019 0.1066 0.1355
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0073 0.009
Toxoplasma gondii subtilisin SUB5 0.0042 0.0129 0.0142
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0081
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Brugia malayi proteasome subunit alpha type 4 0.0248 0.1433 0.1823
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0218
Onchocerca volvulus 0.0071 0.0315 0.0467
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0112 0.0574 0.0728
Toxoplasma gondii subtilisin SUB4 0.0042 0.0129 0.0142
Echinococcus granulosus neuropeptide receptor 0.0575 0.351 0.421
Plasmodium vivax proteasome subunit beta type-1, putative 0.098 0.6073 0.773
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Brugia malayi neuroendocrine convertase 1 precursor 0.0617 0.3771 0.4799
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus granulosus SAM and MBT domain containing protein 0.004 0.0116 0.0139
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Onchocerca volvulus 0.0031 0.0061 0.0029
Loa Loa (eye worm) latrophilin receptor protein 2 0.0041 0.0125 0.0148
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0248 0.1433 0.1433
Entamoeba histolytica cyclin family protein 0.0032 0.0066 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0137 0.0734 0.0932
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0121 0.0152
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0034 0.0021
Plasmodium falciparum glutathione reductase 0.0032 0.0063 0.0078
Brugia malayi von Willebrand Factor 0.0039 0.011 0.0137
Echinococcus multilocularis cyclin b3 0.0032 0.0066 0.0066
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0039 0.011 0.0137
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0365 0.0462
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0093 0.0116
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.098 0.6073 0.6073
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0071 0.0315 0.033
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0607 0.3711 0.3887
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) calpain family protein 1 0.0045 0.0148 0.0176
Loa Loa (eye worm) hypothetical protein 0.0116 0.0601 0.0754
Leishmania major trypanothione reductase 0.0091 0.044 0.0519
Brugia malayi glutathione reductase 0.0091 0.044 0.0558
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Mycobacterium ulcerans beta-lactamase 0.0079 0.0365 0.0388
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium ulcerans proteasome PrcB 0.1261 0.7856 1
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0557 0.0583
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0071 0.0315 0.0399
Schistosoma mansoni cellular tumor antigen P53 0.0031 0.0061 0.0063
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0623 0.0772
Brugia malayi hypothetical protein 0.0081 0.0379 0.0479
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0137 0.0734 0.0932
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0037
Echinococcus granulosus proteasome subunit beta type 7 0.0248 0.1433 0.1719
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Echinococcus multilocularis proteasome subunit alpha type 2 0.0248 0.1433 0.1433
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0245 0.0257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0245 0.027
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.004 0.0116 0.0145
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0155 0.0195
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0039 0.011 0.0128
Schistosoma mansoni site-1 peptidase (S08 family) 0.0042 0.0129 0.0135
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0029 0.0047 0.0057
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0039 0.011 0.0137
Trichomonas vaginalis maltase-glucoamylase, putative 0.0029 0.005 0.0061
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0639 0.067
Toxoplasma gondii thioredoxin reductase 0.0091 0.044 0.0539
Echinococcus granulosus cathepsin L cysteine protease 0.0022 0.0002 0.0002
Echinococcus granulosus proteasome prosome macropain 0.1261 0.7856 0.9421
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0137 0.0734 0.0734
Echinococcus granulosus transcription factor Dp 1 0.0023 0.0009 0.0011

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1500 nM Compounds were tested for their concentration to inhibit the HIV-1 Protease ChEMBL. 8423599
IC50 (binding) = 1500 nM Compounds were tested for their concentration to inhibit the HIV-1 Protease ChEMBL. 8423599

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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