Detailed information for compound 163067

Basic information

Technical information
  • TDR Targets ID: 163067
  • Name: benzyl N-[(2S)-4-amino-1-[[(2S,3R)-3-hydroxy- 4-[methylcarbamoyl(2-methylpropyl)amino]-1-ph enylbutan-2-yl]amino]-1,4-dioxobutan-2-yl]car bamate
  • MW: 541.639 | Formula: C28H39N5O6
  • H donors: 5 H acceptors: 5 LogP: 1.73 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 2
  • SMILES: CNC(=O)N(C[C@H]([C@@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)CC(=O)N)Cc1ccccc1)O)CC(C)C
  • InChi: 1S/C28H39N5O6/c1-19(2)16-33(27(37)30-3)17-24(34)22(14-20-10-6-4-7-11-20)31-26(36)23(15-25(29)35)32-28(38)39-18-21-12-8-5-9-13-21/h4-13,19,22-24,34H,14-18H2,1-3H3,(H2,29,35)(H,30,37)(H,31,36)(H,32,38)/t22-,23-,24+/m0/s1
  • InChiKey: KGHZDRBKSVQHQS-KMDXXIMOSA-N  

Network

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Synonyms

  • benzyl N-[(1S)-3-amino-1-[[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl(methylcarbamoyl)amino]propyl]carbamoyl]-3-oxo-propyl]carbamate
  • N-[(1S)-3-amino-1-[[[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl(methylcarbamoyl)amino]propyl]amino]-oxomethyl]-3-oxopropyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-4-azanyl-1-[[(2S,3R)-3-hydroxy-4-[methylcarbamoyl(2-methylpropyl)amino]-1-phenyl-butan-2-yl]amino]-1,4-dioxo-butan-2-yl]carbamate
  • N-[(1S)-3-amino-1-[[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl(methylcarbamoyl)amino]propyl]carbamoyl]-3-keto-propyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-4-amino-1-[[(2S,3R)-3-hydroxy-4-(methylcarbamoyl-(2-methylpropyl)amino)-1-phenylbutan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamate
  • phenylmethyl N-[(1S)-3-amino-1-[[(1S,2R)-2-hydroxy-3-(isobutyl-(methylcarbamoyl)amino)-1-(phenylmethyl)propyl]carbamoyl]-3-oxo-propyl]carbamate
  • N-[(1S)-3-amino-1-[[[(1S,2R)-2-hydroxy-3-(isobutyl-(methylcarbamoyl)amino)-1-(phenylmethyl)propyl]amino]-oxomethyl]-3-oxopropyl]carbamic acid phenylmethyl ester
  • N-[(1S)-3-amino-1-[[(1S,2R)-1-(benzyl)-2-hydroxy-3-(isobutyl-(methylcarbamoyl)amino)propyl]carbamoyl]-3-keto-propyl]carbamic acid benzyl ester
  • phenylmethyl N-[(2S)-4-amino-1-[[(2S,3R)-3-hydroxy-4-(methylcarbamoyl-(2-methylpropyl)amino)-1-phenyl-butan-2-yl]amino]-1,4-dioxo-butan-2-yl]carbamate
  • (Hydroxyethyl)urea Isostere deriv. 3
  • AIDS004513
  • N-Methyl-N'-isobutyl-N'-[[2(R)-hydroxy-4-phenyl-3(S)-[4-amino-1,4-dioxo-2(S)-[(benzyloxycarbonyl)amino]butylamino]butyl]urea
  • AIDS-004513

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 protease Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) Get druggable targets OG5_131408 All targets in OG5_131408

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei variant surface glycoprotein (VSG), putative Human immunodeficiency virus type 1 protease   99 aa 80 aa 27.5 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Giardia lamblia DNA-directed RNA polymerase subunit D Human immunodeficiency virus type 1 protease   99 aa 90 aa 27.8 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Mycobacterium leprae Hypothetical protein Human immunodeficiency virus type 1 protease   99 aa 86 aa 27.9 %
Echinococcus multilocularis Chromobox protein 3 Human immunodeficiency virus type 1 protease   99 aa 95 aa 28.4 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Toxoplasma gondii proteasome subunit alpha type, putative 0.0248 0.1433 0.1807
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Echinococcus granulosus somatostatin receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0032 0.0066 0.0066
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0067 0.0289 0.0346
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0155 0.0156
Echinococcus granulosus serotonin receptor 0.0071 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0248 0.1433 0.1807
Echinococcus multilocularis cathepsin L 0.0022 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Loa Loa (eye worm) hypothetical protein 0.013 0.0688 0.0865
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0052 0.0192 0.0202
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0047 0.0057
Echinococcus multilocularis nuclear receptor nhr 48 0.0065 0.0274 0.0274
Leishmania major alpha glucosidase II subunit, putative 0.0029 0.005 0.0021
Mycobacterium ulcerans lipase LipD 0.0079 0.0365 0.0388
Giardia lamblia Cyclin A 0.0032 0.0066 0.0004
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0208 0.1179 0.1432
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0248 0.1433 0.1823
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Brugia malayi G protein-coupled receptor F59B2.13 0.0071 0.0315 0.0399
Echinococcus multilocularis cysteine protease 0.0043 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Schistosoma mansoni hypothetical protein 0.0039 0.011 0.0115
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0248 0.1433 0.1823
Onchocerca volvulus Huntingtin homolog 0.0081 0.0379 0.0576
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0137 0.0734 0.0923
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0607 0.3711 0.4722
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0121 0.0444
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.1261 0.7856 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0137 0.0734 0.088
Loa Loa (eye worm) hypothetical protein 0.0045 0.015 0.018
Brugia malayi nuclear receptor NHR-88 0.0137 0.0734 0.0932
Echinococcus multilocularis lamin 0.013 0.0688 0.0688
Onchocerca volvulus 0.0071 0.0315 0.0467
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0116 0.0601 0.069
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0274 0.0274
Trypanosoma cruzi cyclin, putative 0.0051 0.0188 0.0237
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0052 0.0192 0.0201
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Echinococcus multilocularis fmrfamide receptor 0.0071 0.0315 0.0315
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0121 0.0152
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Plasmodium vivax apical sushi protein, putative 0.0067 0.0288 0.0365
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0042 0.0129 0.0135
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0042 0.0129 0.0161
Onchocerca volvulus 0.0067 0.0288 0.0421
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0098 0.0485 0.0485
Mycobacterium leprae proteasome (beta subunit) PrcB 0.1261 0.7856 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0137 0.0734 0.0923
Loa Loa (eye worm) hypothetical protein 0.0081 0.0379 0.0471
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0231 0.1326 0.1621
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0121 0.0152
Echinococcus granulosus lysosomal alpha glucosidase 0.0133 0.0705 0.0845
Onchocerca volvulus 0.0039 0.011 0.0114
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0981 0.6082 0.6371
Toxoplasma gondii subtilisin SUB4 0.0042 0.0129 0.0142
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0039 0.011 0.011
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0121 0.0152
Plasmodium vivax proteasome subunit beta type-5, putative 0.1261 0.7856 1
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0248 0.1433 0.1823
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.005 0.0061
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0073 0.0323 0.0323
Echinococcus multilocularis Furin 1 0.0232 0.1332 0.1332
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.098 0.6073 0.7721
Echinococcus multilocularis dnaJ subfamily B 0.0555 0.3381 0.3381
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Entamoeba histolytica cysteine protease, putative 0.0043 0.0133 0.0167
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0041 0.0125 0.015
Echinococcus granulosus pyruvate kinase 0.0033 0.0073 0.0087
Echinococcus multilocularis SAM and MBT domain containing protein 0.004 0.0116 0.0116
Echinococcus granulosus cathepsin L cysteine proteinase 0.0043 0.0133 0.0159
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0042 0.0129 0.0085
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0248 0.1433 0.1823
Toxoplasma gondii peptidase, T1 family protein 0.0248 0.1433 0.1807
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0034 0.0031
Brugia malayi AKH receptor 0.0071 0.0315 0.0399
Echinococcus multilocularis c4b binding protein beta chain 0.0067 0.0288 0.0288
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.098 0.6073 0.6073
Schistosoma mansoni microtubule-associated protein tau 0.1337 0.8338 0.8734
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0065 0.0274 0.0287
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0043 0.0133 0.0153
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0063 0.0037
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Loa Loa (eye worm) cysteine protease 0.0043 0.0133 0.0157
Trichomonas vaginalis esterase, putative 0.0079 0.0365 0.0462
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0137 0.0734 0.0923
Echinococcus multilocularis histone acetyltransferase MYST2 0.0045 0.015 0.015
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0596 0.3642 0.4635
Schistosoma mansoni biogenic amine receptor 0.0071 0.0315 0.033
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0261
Trichomonas vaginalis set domain proteins, putative 0.0946 0.5858 0.7457
Echinococcus multilocularis 0.0791 0.4879 0.4879
Echinococcus granulosus phd:f box containing protein 0.0027 0.0034 0.004
Schistosoma mansoni integrin alpha 0.0148 0.0803 0.0841
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0133 0.0167
Entamoeba histolytica cyclin, putative 0.0032 0.0066 0.0082
Echinococcus multilocularis thioredoxin glutathione reductase 0.0091 0.0442 0.0442
Loa Loa (eye worm) hypothetical protein 0.0046 0.0155 0.0186
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Leishmania major pyruvate kinase 0.0033 0.0073 0.005
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0241 0.0295
Onchocerca volvulus 0.0039 0.011 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Brugia malayi proteasome subunit beta type 2 0.0607 0.3711 0.4722
Brugia malayi Latrophilin receptor protein 2 0.0041 0.0125 0.0157
Onchocerca volvulus 0.0071 0.0315 0.0467
Brugia malayi latrophilin 2 splice variant baaae 0.0089 0.043 0.0545
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0071 0.0315 0.0315
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0155 0.0119
Brugia malayi jmjC domain containing protein 0.0101 0.0503 0.0638
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0248 0.1433 0.1502
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0036 0.0093 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0009 0.0009
Echinococcus granulosus thioredoxin glutathione reductase 0.0091 0.0442 0.053
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0034 0.0082 0.0024
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) hypothetical protein 0.0051 0.0188 0.0228
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0133 0.0167
Schistosoma mansoni neuropeptide receptor 0.0071 0.0315 0.033
Plasmodium falciparum pyruvate kinase 0.0033 0.0073 0.009
Brugia malayi Protein set-1 0.0078 0.0358 0.0453
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0055 0.0055
Echinococcus granulosus neuropeptide FF receptor 2 0.0071 0.0315 0.0378
Onchocerca volvulus 0.004 0.0116 0.0124
Echinococcus multilocularis microtubule associated protein 2 0.1337 0.8338 0.8338
Brugia malayi hypothetical protein 0.0039 0.011 0.0137
Schistosoma mansoni biogenic amine (5HT) receptor 0.0071 0.0315 0.033
Echinococcus granulosus tm gpcr rhodopsin 0.0071 0.0315 0.0378
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0039 0.011 0.0137
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.001 0.001
Schistosoma mansoni biogenic amine receptor 0.0071 0.0315 0.033
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0231 0.1326 0.1621
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0081
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0378
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0137 0.0734 0.0932
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Brugia malayi putative neuropeptide receptor 0.0071 0.0315 0.0399
Echinococcus multilocularis mitogen activated protein kinase 0.0036 0.0093 0.0093
Loa Loa (eye worm) CUTiclin-Like family member 0.0039 0.011 0.0128
Echinococcus granulosus allatostatin A receptor 0.0071 0.0315 0.0378
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0063 0.0078
Loa Loa (eye worm) hypothetical protein 0.0042 0.0129 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0022 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0063 0.0078
Plasmodium vivax proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Echinococcus granulosus furin 0.0981 0.6082 0.7294
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0248 0.1433 0.1759
Brugia malayi proteasome subunit beta type 3 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Toxoplasma gondii subtilisin SUB9 0.0042 0.0129 0.0142
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0073 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0121 0.0152
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0121 0.0075
Mycobacterium tuberculosis Probable reductase 0.0208 0.1179 0.1432
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0043 0.0133 0.0153
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) mbt repeat family protein 0.004 0.0116 0.0135
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0063 0.0078
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0048 0.0167 0.021
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0073 0.0013
Onchocerca volvulus Bile acid receptor homolog 0.0137 0.0734 0.1187
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0073 0.009
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0035 0.0087 0.0108
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0137 0.0734 0.0734
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0036 0.0093 0.0076
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0607 0.3711 0.4722
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0248 0.1433 0.1502
Trichomonas vaginalis cyclins, putative 0.0032 0.0066 0.0082
Loa Loa (eye worm) TAR-binding protein 0.0191 0.1076 0.136
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0034 0.004
Chlamydia trachomatis pyruvate kinase 0.0033 0.0073 0.0637
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0248 0.1433 0.1815
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0071 0.0315 0.0315
Onchocerca volvulus 0.0067 0.0288 0.0421
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0365 0.0388
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.004 0.0116 0.0105
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni alpha-glucosidase 0.0114 0.0587 0.0615
Loa Loa (eye worm) hypothetical protein 0.0385 0.2302 0.2922
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.098 0.6073 0.6361
Loa Loa (eye worm) hypothetical protein 0.0131 0.0692 0.087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0075
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Brugia malayi Serotonin receptor 0.0071 0.0315 0.0399
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Treponema pallidum hypothetical protein 0.0039 0.011 0.0357
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0137 0.0734 0.088
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0073 0.009
Echinococcus granulosus citrate lyase subunit beta protein 0.0048 0.0167 0.0201
Echinococcus granulosus proteasome subunit alpha type 6 0.0248 0.1433 0.1719
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0176
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0199
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0275
Trypanosoma cruzi cysteine peptidase, putative 0.0043 0.0133 0.0167
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Loa Loa (eye worm) proteasome subunit beta type 3 0.0248 0.1433 0.1815
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0137 0.0734 0.088
Brugia malayi Pre-SET motif family protein 0.0832 0.5133 0.6534
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0157
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0066 0.0082
Schistosoma mansoni opsin-like receptor 0.0071 0.0315 0.033
Echinococcus granulosus proteasome prosome macropain 0.1261 0.7856 0.9421
Leishmania major subtilisin-like serine peptidase 0.0042 0.0129 0.0122
Onchocerca volvulus 0.0137 0.0734 0.1187
Toxoplasma gondii proteasome subunit beta type 1, putative 0.098 0.6073 0.7725
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.004 0.0116 0.0121
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0596 0.3642 0.4635
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0274 0.0287
Entamoeba histolytica elongation factor-2 kinase, putative 0.0039 0.011 0.0137
Schistosoma mansoni cpg binding protein 0.006 0.0241 0.0253
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0034 0.0034
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis serotonin receptor 0.0071 0.0315 0.0315
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0112 0.0574 0.0728
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0042 0.0129 0.0161
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0052 0.0192 0.0165
Entamoeba histolytica hypothetical protein 0.0039 0.011 0.0137
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0248 0.1433 0.1823
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0245 0.0234
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Echinococcus granulosus pyruvate kinase 0.0033 0.0073 0.0087
Brugia malayi Melatonin receptor type 1A 0.0071 0.0315 0.0399
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0036 0.0093 0.0096
Toxoplasma gondii proteasome subunit alpha1, putative 0.0248 0.1433 0.1807
Echinococcus granulosus collagen alpha 1VII chain 0.0039 0.011 0.0132
Giardia lamblia 20S proteasome alpha subunit 5 0.0248 0.1433 0.1759
Echinococcus multilocularis neuropeptide Y receptor 0.0071 0.0315 0.0315
Echinococcus granulosus neuropeptides capa receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0121 0.0152
Loa Loa (eye worm) histone methyltransferase 0.0025 0.0023 0.0018
Schistosoma mansoni site-1 peptidase (S08 family) 0.0042 0.0129 0.0135
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0091 0.0439 0.0557
Echinococcus granulosus cyclin b3 0.0032 0.0066 0.0079
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1261 0.7856 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0607 0.3711 0.4722
Echinococcus granulosus integrin alpha 3 0.0114 0.0583 0.07
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus granulosus cathepsin L cysteine protease 0.0022 0.0002 0.0002
Echinococcus granulosus dnaJ subfamily B 0.0555 0.3381 0.4055
Schistosoma mansoni hypothetical protein 0.0039 0.011 0.0115
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Leishmania major cysteine peptidase A (CPA) 0.0043 0.0133 0.0127
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0065 0.0274 0.0337
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.1348 0.1706
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus granulosus tachykinin peptides receptor 99D 0.0071 0.0315 0.0378
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0071 0.0315 0.0315
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus granulosus proteasome subunit alpha type 2 0.0248 0.1433 0.1719
Brugia malayi 20S proteasome alpha5 subunit 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0091 0.0439 0.068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0365 0.0388
Schistosoma mansoni histone-lysine n-methyltransferase seto7 0.0078 0.0358 0.0375
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Toxoplasma gondii subtilisin SUB1 0.0042 0.0129 0.0142
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0315
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0274 0.0346
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0065 0.0274 0.0346
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.1433 0.1815
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0133 0.0705 0.0886
Trichomonas vaginalis cyclin D, putative 0.0032 0.0066 0.0082
Schistosoma mansoni neuropeptide receptor 0.0575 0.351 0.3677
Loa Loa (eye worm) proprotein convertase 2 0.0232 0.1332 0.1685
Echinococcus granulosus neuropeptide receptor A26 0.036 0.2142 0.2569
Brugia malayi beta-lactamase family protein 0.0079 0.0365 0.0462
Plasmodium falciparum thioredoxin reductase 0.0091 0.044 0.0558
Brugia malayi G protein-coupled receptor 0.0071 0.0315 0.0399
Echinococcus granulosus Proteasome subunit alpha beta 0.0248 0.1433 0.1719
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis integrin alpha ps 0.0066 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Giardia lamblia Proteasome subunit beta type 1 0.098 0.6073 0.7712
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0051 0.0188 0.0197
Loa Loa (eye worm) hypothetical protein 0.006 0.0246 0.0302
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0034 0.0021
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0042 0.0129 0.0072
Giardia lamblia 20S proteasome alpha subunit 3 0.0248 0.1433 0.1759
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0071 0.0315 0.0315
Leishmania major proteasome alpha 7 subunit, putative 0.0248 0.1433 0.179
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Onchocerca volvulus 0.0067 0.0288 0.0421
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0274 0.0328
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.005
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0248 0.1433 0.1719
Entamoeba histolytica cyclin, putative 0.0051 0.0188 0.0237
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0248 0.1433 0.1433
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0137 0.0734 0.088
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0155 0.0119
Toxoplasma gondii cathepsin CPL 0.0043 0.0133 0.0148
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0043 0.0133 0.0133
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Leishmania major proteasome alpha 2 subunit, putative 0.0248 0.1433 0.179
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0034 0.004
Plasmodium vivax thrombospondin-related anonymous protein 0.0039 0.011 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0137 0.0734 0.0932
Onchocerca volvulus 0.0039 0.011 0.0114
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi Subtilase family protein 0.0042 0.0129 0.0161
Brugia malayi G-protein coupled receptor 0.0071 0.0315 0.0399
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi orphan nuclear receptor NR2E1 0.0065 0.0274 0.0346
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0073 0.009
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Echinococcus granulosus fmrfamide receptor 0.0071 0.0315 0.0378
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0248 0.1433 0.1815
Echinococcus multilocularis neuropeptide receptor 0.0071 0.0315 0.0315
Mycobacterium leprae Possible secreted protease 0.0042 0.0129 0.0072
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0248 0.1433 0.1502
Onchocerca volvulus 0.0043 0.0133 0.0153
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0218
Mycobacterium tuberculosis Conserved protein 0.0079 0.0365 0.0388
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0137 0.0734 0.0734
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Brugia malayi neuropeptide F receptor 0.0071 0.0315 0.0399
Echinococcus multilocularis proteasome subunit alpha type 2 0.0248 0.1433 0.1433
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.098 0.6073 0.773
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0043 0.0133 0.0167
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0071 0.0315 0.033
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0042 0.0129 0.0161
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0042 0.0129 0.0161
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0248 0.1433 0.1823
Toxoplasma gondii exonuclease III APE 0.0041 0.0121 0.0132
Brugia malayi conserved hypotetical protein 0.0065 0.0274 0.0346
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0093 0.0116
Onchocerca volvulus Cathepsin F homolog 0.0043 0.0133 0.0153
Echinococcus granulosus proteasome subunit beta t family 0.0248 0.1433 0.1719
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0101 0.0503 0.0503
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.004 0.0116 0.0136
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1261 0.7856 1
Onchocerca volvulus 0.0071 0.0315 0.0467
Loa Loa (eye worm) WD40 repeat protein 0.0283 0.1657 0.21
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0365 0.0462
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0248 0.1433 0.1823
Brugia malayi hypothetical protein 0.0081 0.0379 0.0479
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0121 0.0145
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0068 0.0296 0.0296
Mycobacterium ulcerans 3-dehydroquinate dehydratase 0.1162 0.7227 0.9194
Loa Loa (eye worm) PAS-3 protein 0.0248 0.1433 0.1815
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.019 0.1066 0.1355
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0639 0.067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0073 0.0323 0.04
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.006 0.0241 0.034
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0116 0.0145
Brugia malayi RNA recognition motif domain containing protein 0.0191 0.1076 0.1368
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0071 0.0315 0.0399
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.1261 0.7856 0.8229
Onchocerca volvulus Notchless protein homolog 0.0248 0.1433 0.239
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0155 0.0195
Onchocerca volvulus 0.0039 0.011 0.0114
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Echinococcus multilocularis cyclin B 0.0051 0.0188 0.0188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Trypanosoma brucei subtilisin peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0071 0.0315 0.033
Brugia malayi Nuclear hormone receptor-like 1 0.0137 0.0734 0.0932
Schistosoma mansoni jumonji/arid domain-containing protein 0.0104 0.0525 0.0549
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.1433 0.1815
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0073 0.009
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0248 0.1433 0.1433
Echinococcus granulosus biogenic amine 5HT receptor 0.0071 0.0315 0.0378
Giardia lamblia 20S proteasome alpha subunit 6 0.0248 0.1433 0.1759
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0137 0.0734 0.0734
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0137 0.0734 0.1187
Entamoeba histolytica cyclin family protein 0.0032 0.0066 0.0082
Schistosoma mansoni hypothetical protein 0.019 0.1066 0.1117
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Onchocerca volvulus Neuropeptide F receptor homolog 0.0071 0.0315 0.0467
Loa Loa (eye worm) hypothetical protein 0.0116 0.0601 0.0754
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Onchocerca volvulus 0.0071 0.0315 0.0467
Loa Loa (eye worm) proteasome subunit beta type 1 0.098 0.6073 0.7728
Brugia malayi GnHR receptor homolog 0.0071 0.0315 0.0399
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0071 0.0315 0.0399
Onchocerca volvulus 0.0067 0.0288 0.0421
Mycobacterium leprae 3-dehydroquinate dehydratase AroD (AroQ) (3-dehydroquinase) (Type II DHQase) 0.1162 0.7227 0.9193
Echinococcus granulosus SAM and MBT domain containing protein 0.004 0.0116 0.0139
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0063 0.0058
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0071 0.0315 0.033
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0365 0.0388
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0248 0.1433 0.1823
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0078
Toxoplasma gondii ABC1 family protein 0.0079 0.0365 0.0444
Loa Loa (eye worm) melatonin receptor type 1A 0.0071 0.0315 0.039
Echinococcus granulosus histone acetyltransferase MYST2 0.0045 0.015 0.018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0071 0.0315 0.0315
Echinococcus multilocularis C type lectin domian containing protein 0.0067 0.0288 0.0288
Brugia malayi proteasome subunit beta type 1 0.098 0.6073 0.773
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Echinococcus multilocularis integrin alpha ps 0.0032 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0068 0.0296 0.0355
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0068 0.0296 0.0296
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0155 0.0119
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0137 0.0734 0.0923
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0093 0.0116
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0231 0.1326 0.161
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0245 0.0257
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Brugia malayi hypothetical protein 0.0065 0.0274 0.0346
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Leishmania major proteasome alpha 1 subunit, putative 0.0248 0.1433 0.179
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Loa Loa (eye worm) latrophilin receptor protein 2 0.0041 0.0125 0.0148
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) G-protein coupled receptor 0.0071 0.0315 0.039
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Onchocerca volvulus 0.0283 0.1657 0.2774
Echinococcus granulosus lysine specific demethylase 5A 0.0104 0.0525 0.0629
Brugia malayi nuclear receptor RXR 0.0065 0.0274 0.0346
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0248 0.1433 0.1502
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0639 0.067
Onchocerca volvulus 0.0077 0.035 0.0526
Schistosoma mansoni hypothetical protein 0.0089 0.043 0.045
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0052 0.0192 0.0201
Schistosoma mansoni integrin alpha-ps 0.0066 0.0284 0.0298
Brugia malayi Steroid receptor seven-up type 2 0.0137 0.0734 0.0932
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0046 0.0155 0.0192
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0045 0.015 0.015
Echinococcus granulosus tm gpcr rhodopsin 0.0071 0.0315 0.0378
Echinococcus granulosus membrane bound transcription factor site 1 0.0042 0.0129 0.0154
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.005
Leishmania major hypothetical protein, conserved 0.0417 0.2505 0.3159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Treponema pallidum fructose-bisphosphate aldolase 0.0238 0.1373 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0036 0.0093 0.0116
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0037 0.0096 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Loa Loa (eye worm) intermediate filament protein 0.013 0.0688 0.0865
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0079 0.0365 0.0553
Brugia malayi neuroendocrine convertase 1 precursor 0.0617 0.3771 0.4799
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0064 0.0268 0.033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Brugia malayi ecdysone receptor 0.0065 0.0274 0.0346
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0547 0.3328 0.423
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0122 0.0639 0.0639
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0208 0.1179 0.1432
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0039 0.011 0.0128
Brugia malayi proteasome subunit alpha type 1 0.0248 0.1433 0.1823
Giardia lamblia Proteasome subunit beta type 3 0.0248 0.1433 0.1759
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Brugia malayi Cathepsin L-like precursor 0.0028 0.0044 0.0053
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0248 0.1433 0.1502
Brugia malayi nuclear hormone receptor family member odr-7 0.0065 0.0274 0.0346
Entamoeba histolytica cyclin family protein 0.0032 0.0066 0.0082
Leishmania major trypanothione reductase 0.0091 0.044 0.0519
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus granulosus mitogen activated protein kinase 0.0036 0.0093 0.0111
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0248 0.1433 0.1823
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0481 0.0572
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0116 0.0121
Brugia malayi hypothetical protein 0.0113 0.0581 0.0738
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0063 0.0058
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0055 0.0066
Onchocerca volvulus 0.0079 0.0365 0.0553
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0093 0.0097
Schistosoma mansoni cellular tumor antigen P53 0.0031 0.0061 0.0063
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0365 0.0388
Echinococcus granulosus calpain A 0.0067 0.0289 0.0346
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0192 0.0242
Brugia malayi von Willebrand Factor 0.0039 0.011 0.0137
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.005 0.0061
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 1
Echinococcus multilocularis proteasome subunit beta type 6 0.0248 0.1433 0.1433
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Echinococcus multilocularis lysosomal alpha glucosidase 0.0133 0.0705 0.0705
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Trypanosoma brucei hypothetical protein, conserved 0.0417 0.2505 0.3187
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Onchocerca volvulus 0.013 0.0688 0.1108
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0557 0.0583
Trypanosoma brucei glucosidase, putative 0.0029 0.005 0.0061
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0031
Mycobacterium ulcerans proteasome PrcA 0.0248 0.1433 0.1759
Onchocerca volvulus 0.0043 0.0133 0.0153
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Brugia malayi proteasome subunit alpha type 4 0.0248 0.1433 0.1823
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0639 0.067
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0581 0.0609
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0296 0.031
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0248 0.1433 0.1815
Echinococcus multilocularis cathepsin L cysteine protease 0.0043 0.0133 0.0133
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0041 0.0125 0.0125
Echinococcus granulosus C type lectin domian containing protein 0.0067 0.0288 0.0346
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0365 0.0462
Brugia malayi Cyclin, N-terminal domain containing protein 0.0051 0.0188 0.0237
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.005 0.0061
Leishmania major proteasome alpha 3 subunit, putative 0.0248 0.1433 0.179
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0073 0.009
Brugia malayi proteasome subunit alpha type 3 0.0248 0.1433 0.1823
Echinococcus granulosus tumor protein p63 0.0213 0.1213 0.1455
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0073 0.009
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.0044 0.0046
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0248 0.1433 0.1502
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0248 0.1433 0.1502
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0101 0.0503 0.0603
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0052 0.0192 0.023
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0056 0.0218 0.0256
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0034 0.004
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0116 0.0145
Echinococcus granulosus subfamily T1A non peptidase ue 0.0248 0.1433 0.1719
Brugia malayi calpain family protein 1 0.0064 0.0268 0.0339
Brugia malayi calpain family protein 1 0.0064 0.0268 0.0339
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Trichomonas vaginalis hypothetical protein 0.019 0.1066 0.1355
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0029 0.005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Trypanosoma cruzi major cysteine proteinase, putative 0.0127 0.0671 0.0852
Brugia malayi Thioredoxin reductase 0.0091 0.044 0.0558
Echinococcus granulosus neuropeptides capa receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Trichomonas vaginalis WD repeat domain, putative 0.0283 0.1657 0.2107
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) RNA binding protein 0.0191 0.1076 0.136
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.004 0.0116 0.0124
Echinococcus granulosus neuropeptide receptor 0.0575 0.351 0.421
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0232 0.1332 0.1395
Echinococcus multilocularis neuropeptide receptor A26 0.036 0.2142 0.2142
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0029 0.0047 0.0057
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Brugia malayi Dopamine receptor protein 2 0.0071 0.0315 0.0399
Echinococcus granulosus GPCR family 2 0.0041 0.0125 0.015
Echinococcus granulosus c4b binding protein beta chain 0.0067 0.0288 0.0346
Brugia malayi proteasome subunit alpha type 6 0.0248 0.1433 0.1823
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.1261 0.7856 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Leishmania major hypothetical protein, conserved 0.0079 0.0365 0.0424
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0176
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0039 0.011 0.0137
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0063 0.0078
Toxoplasma gondii thioredoxin reductase 0.0091 0.044 0.0539
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0208 0.1179 0.1432
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Onchocerca volvulus 0.0071 0.0315 0.0467
Leishmania major proteasome beta 2 subunit, putative 0.0607 0.3711 0.4701
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0034 0.0031
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0148 0.0802 0.1019
Brugia malayi TAR-binding protein 0.0191 0.1076 0.1368
Mycobacterium tuberculosis Probable oxidoreductase 0.0231 0.1326 0.1621
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0248 0.1433 0.1823
Brugia malayi proteasome subunit alpha type 2 0.0248 0.1433 0.1823
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0256 0.1483 0.1553
Echinococcus granulosus proteasome subunit beta type 7 0.0248 0.1433 0.1719
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Brugia malayi ORL1-like opioid receptor 0.0071 0.0315 0.0399
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Schistosoma mansoni peptidase Clp (S14 family) 0.0056 0.0218 0.0228
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0071 0.0315 0.0315
Trypanosoma brucei protein kinase, putative 0.0036 0.0093 0.0116
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0248 0.1433 0.179
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.013 0.0688 0.0865
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0155 0.0119
Loa Loa (eye worm) hypothetical protein 0.006 0.0246 0.0302
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Brugia malayi sulfakinin receptor protein 0.0071 0.0315 0.0399
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0121 0.0152
Brugia malayi Pre-SET motif family protein 0.0122 0.0639 0.0811
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Loa Loa (eye worm) endoprotease bli-4 0.0981 0.6082 0.7739
Loa Loa (eye worm) steroid hormone receptor 0.0137 0.0734 0.0923
Brugia malayi RNA binding protein 0.0191 0.1076 0.1368
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0034 0.0035
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0071 0.0315 0.033
Echinococcus granulosus voltage dependent calcium channel subunit 0.0039 0.011 0.0132
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0071 0.0315 0.0315
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0248 0.1433 0.1823
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni opsin-like receptor 0.0071 0.0315 0.033
Schistosoma mansoni survival motor neuron protein 0.0091 0.0439 0.046
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0248 0.1433 0.1719
Schistosoma mansoni neuropeptide f receptor 76f 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Echinococcus granulosus neuropeptide s receptor 0.036 0.2142 0.2569
Brugia malayi GCC2 and GCC3 family protein 0.0067 0.0288 0.0365
Echinococcus granulosus cathepsin l cysteine peptidase 0.0043 0.0133 0.0159
Schistosoma mansoni nuclear receptor 0.0065 0.0274 0.0287
Plasmodium falciparum acyl-CoA synthetase 0.0034 0.0082 0.0101
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0066
Echinococcus multilocularis g protein coupled receptor 0.0071 0.0315 0.0315
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Echinococcus multilocularis integrin alpha ps 0.0066 0.0284 0.0284
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0245 0.027
Brugia malayi beta-lactamase family protein 0.0079 0.0365 0.0462
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0041 0.0125 0.0157
Schistosoma mansoni alpha-glucosidase 0.0114 0.0587 0.0615
Onchocerca volvulus 0.0043 0.0133 0.0153
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0167 0.0171
Echinococcus multilocularis cyclin B3 1 0.0032 0.0066 0.0066
Brugia malayi MH2 domain containing protein 0.0234 0.1348 0.1714
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0137 0.0734 0.0734
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi hypothetical protein 0.0073 0.0323 0.0409
Plasmodium vivax proteasome subunit beta type-4, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0112 0.0574 0.0719
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Onchocerca volvulus 0.0071 0.0315 0.0467
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.001 0.001
Loa Loa (eye worm) calpain family protein 1 0.0045 0.0148 0.0176
Schistosoma mansoni lamin 0.013 0.0688 0.072
Echinococcus granulosus FTZ F1 alpha 0.0137 0.0734 0.088
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0248 0.1433 0.1433
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis cysteine protease 0.0043 0.0133 0.0133
Schistosoma mansoni jumonji/arid domain-containing protein 0.0104 0.0525 0.0549
Plasmodium vivax SET domain protein, putative 0.0078 0.0358 0.0453
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0245 0.029
Echinococcus granulosus thyroid hormone receptor alpha 0.0065 0.0274 0.0328
Trypanosoma cruzi cysteine peptidase, putative 0.0162 0.0891 0.1132
Echinococcus multilocularis dro:myosuppressin receptor 0.0071 0.0315 0.0315
Plasmodium vivax glutathione reductase, putative 0.0091 0.044 0.0558
Echinococcus multilocularis sex peptide receptor 0.0071 0.0315 0.0315
Mycobacterium tuberculosis Conserved hypothetical protein 0.0108 0.0551 0.0626
Echinococcus multilocularis peptidase Clp (S14 family) 0.0037 0.0096 0.0096
Plasmodium vivax SET domain protein, putative 0.0122 0.0639 0.0811
Giardia lamblia Hypothetical protein 0.0032 0.0066 0.0004
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis beta adrenergic receptor kinase 0.0109 0.0557 0.0557
Trypanosoma cruzi cruzipain precursor, putative 0.0162 0.0891 0.1132
Echinococcus granulosus g protein coupled receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Onchocerca volvulus Cathepsin L homolog 0.0043 0.0133 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0137 0.0734 0.0932
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0607 0.3711 0.3711
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0032 0.0065 0.0071
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.1433 0.1823
Echinococcus granulosus nuclear receptor nhr 48 0.0065 0.0274 0.0328
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Mycobacterium tuberculosis Conserved protein 0.0079 0.0365 0.0388
Echinococcus granulosus neuroendocrine convertase 2 0.0617 0.3771 0.4522
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.005 0.0061
Echinococcus granulosus cpg binding protein 0.0063 0.0263 0.0315
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0365 0.0383
Toxoplasma gondii subtilisin SUB6 0.0042 0.0129 0.0142
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Schistosoma mansoni integrin alpha-ps 0.0035 0.0082 0.0086
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0065 0.0274 0.0287
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0245 0.0234
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0073 0.0323 0.0338
Echinococcus granulosus lamin 0.013 0.0688 0.0825
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0071 0.0315 0.033
Echinococcus multilocularis g-protein coupled receptor 0.0071 0.0315 0.0315
Echinococcus granulosus tm gpcr rhodopsin 0.0071 0.0315 0.0378
Loa Loa (eye worm) neuropeptide F receptor 0.0071 0.0315 0.039
Echinococcus granulosus cyclin B3 1 0.0032 0.0066 0.0079
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0155 0.0156
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0056 0.0218 0.0266
Brugia malayi intermediate filament protein 0.013 0.0688 0.0873
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0137 0.0734 0.0923
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Plasmodium vivax vivapain-2 0.0043 0.0133 0.0167
Brugia malayi photoreceptor-specific nuclear receptor 0.0137 0.0734 0.0932
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0043 0.0133 0.0157
Brugia malayi Will die slowly protein 0.0283 0.1657 0.2107
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Leishmania major mitochondrial DNA polymerase beta 0.0206 0.1168 0.1451
Schistosoma mansoni opsin-like receptor 0.0071 0.0315 0.033
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0097 0.0481 0.061
Trypanosoma cruzi trypanothione reductase, putative 0.0091 0.044 0.0558
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0137 0.0734 0.0734
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0248 0.1433 0.1433
Loa Loa (eye worm) hypothetical protein 0.0041 0.0125 0.0148
Giardia lamblia G2/mitotic-specific cyclin B 0.0051 0.0188 0.0161
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0155 0.0195
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0607 0.3711 0.445
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0274 0.0328
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0245 0.0234
Echinococcus multilocularis citrate lyase subunit beta protein 0.0048 0.0167 0.0167
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0155 0.0195
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Onchocerca volvulus 0.0039 0.011 0.0114
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0041 0.0125 0.0125
Echinococcus multilocularis neuropeptides capa receptor 0.0071 0.0315 0.0315
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0073 0.005
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0133 0.0167
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0073 0.0323 0.0338
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) MBCTL1 0.0045 0.015 0.018
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0323 0.0409
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Brugia malayi Proteasome subunit alpha type 1 0.0248 0.1433 0.1823
Schistosoma mansoni myosin xvIII 0.0071 0.0315 0.033
Echinococcus multilocularis neuropeptide s receptor 0.036 0.2142 0.2142
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0081
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0248 0.1433 0.1823
Brugia malayi Zona pellucida-like domain containing protein 0.0039 0.011 0.0137
Schistosoma mansoni coup transcription factor 0.0137 0.0734 0.0769
Echinococcus multilocularis geminin 0.0452 0.273 0.273
Trichomonas vaginalis cyclin B3, putative 0.0032 0.0066 0.0082
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0155 0.0156
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0248 0.1433 0.1433
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.0133 0.0157
Schistosoma mansoni hypothetical protein 0.0452 0.273 0.286
Brugia malayi tailless protein 0.0065 0.0274 0.0346
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0071 0.0315 0.0378
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0365 0.0462
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0043 0.0133 0.0167
Schistosoma mansoni hypothetical protein 0.025 0.145 0.1519
Onchocerca volvulus 0.0039 0.011 0.0114
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Leishmania major cathepsin L-like protease 0.0162 0.0891 0.1096
Schistosoma mansoni histamine h1 receptor 0.0071 0.0315 0.033
Toxoplasma gondii subtilisin SUB12 0.0042 0.0129 0.0142
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus multilocularis survival motor neuron protein 1 0.0446 0.2688 0.2688
Toxoplasma gondii rhoptry neck protein RON1 0.0067 0.0288 0.0346
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.007 0.0305 0.0377
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0155 0.0195
Onchocerca volvulus 0.0071 0.0315 0.0467
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Loa Loa (eye worm) hypothetical protein 0.0034 0.0082 0.0092
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Plasmodium falciparum proteasome subunit beta type-4 0.0248 0.1433 0.1823
Schistosoma mansoni pyruvate kinase 0.0033 0.0073 0.0076
Onchocerca volvulus 0.0031 0.0061 0.0029
Brugia malayi Sushi domain 0.0067 0.0288 0.0365
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0063 0.0261 0.0261
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis lysosomal alpha glucosidase 0.0133 0.0705 0.0705
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0071 0.0315 0.0315
Mycobacterium ulcerans hypothetical protein 0.0046 0.0155 0.0119
Leishmania major proteasome beta 7 subunit, putative 0.0248 0.1433 0.179
Leishmania major proteasome alpha 1 subunit, putative 0.0248 0.1433 0.179
Echinococcus granulosus histone lysine methyltransferase setb 0.0122 0.0639 0.0767
Brugia malayi ecdysteroid receptor 0.0137 0.0734 0.0932
Brugia malayi cytoplasmic intermediate filament protein 0.007 0.0305 0.0386
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0365 0.0462
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0248 0.1433 0.1719
Loa Loa (eye worm) ctsf protein 0.0043 0.0133 0.0157
Mycobacterium tuberculosis Conserved protein 0.0079 0.0365 0.0388
Echinococcus multilocularis calpain family protein 1, d 0.0045 0.0148 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0034 0.004
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0248 0.1433 0.1823
Schistosoma mansoni nuclear hormone receptor 0.0137 0.0734 0.0769
Trypanosoma cruzi cyclin 6, putative 0.0051 0.0188 0.0237
Schistosoma mansoni cyclin B 0.0051 0.0188 0.0197
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0034 0.004
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0047 0.0057
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Echinococcus granulosus orexin receptor type 2 0.0071 0.0315 0.0378
Schistosoma mansoni hypothetical protein 0.0283 0.1657 0.1735
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Echinococcus granulosus proteasome prosome macropain subunit beta 0.098 0.6073 0.7283
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0137 0.0734 0.0932
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni neuropeptide F-like receptor 0.0071 0.0315 0.033
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0365 0.0388
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0365 0.0462
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0192 0.0242
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis protein will die slowly 0.0283 0.1657 0.1657
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0274 0.0396
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0137 0.0734 0.0734
Toxoplasma gondii proteasome subunit 0.0248 0.1433 0.1807
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0248 0.1433 0.1807
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0042 0.0129 0.0085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0065 0.0274 0.0328
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0315
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0071 0.0315 0.0399
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Toxoplasma gondii subtilisin SUB11 0.0042 0.0129 0.0142
Trichomonas vaginalis sucrase-isomaltase, putative 0.0029 0.005 0.0061
Toxoplasma gondii microneme protein MIC2 0.0039 0.011 0.0118
Loa Loa (eye worm) hypothetical protein 0.0081 0.0379 0.0471
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.004 0.0116 0.0116
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.1261 0.7856 1
Mycobacterium leprae Probable lipase LipE 0.0079 0.0365 0.0376
Mycobacterium ulcerans hypothetical protein 0.0079 0.0365 0.0388
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0121 0.0142
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0034 0.0035
Brugia malayi nuclear hormone receptor family member nhr-6 0.0065 0.0274 0.0346
Plasmodium vivax proteasome subunit beta type-3, putative 0.0248 0.1433 0.1823
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.0639 0.0639
Brugia malayi G-protein coupled receptor 0.0071 0.0315 0.0399
Schistosoma mansoni cpg binding protein 0.0063 0.0263 0.0275
Echinococcus granulosus mitogen activated protein kinase 3 0.0036 0.0093 0.0111
Echinococcus granulosus tar DNA binding protein 0.0191 0.1076 0.1291
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0274 0.0287
Echinococcus multilocularis G protein coupled receptor 139 0.0575 0.351 0.351
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0116 0.0601 0.069
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Echinococcus granulosus transcription factor Dp 1 0.0023 0.0009 0.0011
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0034 0.004
Loa Loa (eye worm) CUTiclin family member 0.0039 0.011 0.0128
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0037
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0121 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0044 0.0053
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0071 0.0315 0.039
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0109 0.0557 0.0698
Echinococcus granulosus histone lysine n methyltransferase setd8 0.0078 0.0358 0.0429
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0155 0.0119
Onchocerca volvulus 0.0067 0.0288 0.0421
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Trypanosoma cruzi CYC2-like cyclin, putative 0.0051 0.0188 0.0237
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0073 0.009
Onchocerca volvulus Cathepsin L homolog 0.0043 0.0133 0.0153
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni lamin 0.013 0.0688 0.072
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0116 0.0121
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0248 0.1433 0.1823
Echinococcus granulosus sex peptide receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0042 0.0129 0.0135
Loa Loa (eye worm) subtilase 0.0042 0.0129 0.0152
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0137 0.0734 0.0923
Brugia malayi Cathepsin L-like precursor 0.0028 0.0044 0.0053
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0045 0.015 0.018
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0023 0.0024
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0042 0.0129 0.0161
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.005 0.0061
Brugia malayi cathepsin L-like precursor 0.0028 0.0044 0.0053
Echinococcus multilocularis proteasome (prosome, macropain) 0.1261 0.7856 0.7856
Trypanosoma cruzi cysteine peptidase, putative 0.0162 0.0891 0.1132
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Onchocerca volvulus 0.0051 0.0188 0.0248
Brugia malayi Proteasome A-type and B-type family protein 0.1261 0.7856 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0248 0.1433 0.1823
Schistosoma mansoni hypothetical protein 0.0555 0.3381 0.3542
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0064 0.0268 0.033
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0248 0.1433 0.1823
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0052 0.0192 0.023
Trichomonas vaginalis cyclin A, putative 0.0051 0.0188 0.0237
Brugia malayi Dopamine receptor protein 1 0.0071 0.0315 0.0399
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.0639 0.0794
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0042 0.0129 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0137 0.0734 0.0932
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0071 0.0315 0.0378
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0071 0.0315 0.0378
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus granulosus integrin alpha ps 0.0032 0.0065 0.0078
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0137 0.0734 0.0923
Brugia malayi Cyclin, N-terminal domain containing protein 0.0032 0.0066 0.0082
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0073 0.009
Schistosoma mansoni cyclins 0.0032 0.0066 0.0069
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0068 0.0296 0.0366
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.098 0.6073 0.773
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0052 0.0192 0.0242
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0116 0.0145
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0248 0.1433 0.179
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0037 0.0096 0.0042
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0029 0.0047 0.0057
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0365 0.0454
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0278 0.1624 0.1701
Plasmodium vivax acyl-CoA synthetase, putative 0.0034 0.0082 0.0101
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0022 0.0025
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0034 0.0035
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0248 0.1433 0.1502
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0073 0.0013
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0023 0.0024
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0155 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0248 0.1437 0.1828
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Plasmodium falciparum subtilisin-like protease 3 0.0042 0.0129 0.0161
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0248 0.1433 0.1433
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0137 0.0734 0.0932
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.004 0.0116 0.0139
Leishmania major cyclin 0.0051 0.0188 0.0197
Schistosoma mansoni hypothetical protein 0.0452 0.273 0.286
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0063 0.0078
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0034 0.0021
Echinococcus granulosus ubiquitin specific protease 41 0.0052 0.0192 0.023
Giardia lamblia 20S proteasome alpha subunit 7 0.0248 0.1433 0.1759
Plasmodium falciparum proteasome subunit beta type-1, putative 0.098 0.6073 0.773
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0607 0.3711 0.3887
Echinococcus multilocularis fmrfamide receptor 0.0071 0.0315 0.0315
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0365 0.0388
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0248 0.1433 0.1823
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0208 0.1179 0.1421
Loa Loa (eye worm) hypothetical protein 0.0089 0.043 0.0536
Echinococcus granulosus cathepsin L 0.0022 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0245 0.0294
Echinococcus multilocularis membrane bound transcription factor site 1 0.0042 0.0129 0.0129
Schistosoma mansoni neuropeptide receptor 0.0071 0.0315 0.033
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0063 0.0078
Loa Loa (eye worm) nuclear receptor NHR-67 0.0065 0.0274 0.0337
Loa Loa (eye worm) neuropeptide F receptor 0.0071 0.0315 0.039
Echinococcus multilocularis integrin alpha 3 0.0114 0.0583 0.0583
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0365 0.0462
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0081
Schistosoma mansoni RAR-like nuclear receptor 0.0137 0.0734 0.0769
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0034 0.0034
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0116 0.0601 0.0678
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0068 0.0296 0.0355
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0248 0.1433 0.1815
Plasmodium falciparum SET domain protein, putative 0.0078 0.0358 0.0453
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trypanosoma cruzi 20S proteasome subunit 0.0607 0.3711 0.4722
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0192 0.0242
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0071 0.0315 0.0315
Onchocerca volvulus 0.015 0.0813 0.1324
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0557 0.0583
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0042 0.0129 0.0161
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0056 0.0218 0.0256
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Giardia lamblia Proteasome subunit beta type 5 precursor 0.1261 0.7856 1
Brugia malayi neuropeptide F receptor 0.0071 0.0315 0.0399
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0073 0.0081
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0039 0.011 0.0137
Plasmodium vivax thioredoxin reductase, putative 0.0091 0.044 0.0558
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0022 0.0002 0.0002
Echinococcus granulosus cyclin B 0.0051 0.0188 0.0226
Brugia malayi pregnancy-associated plasma protein-A 0.0067 0.0288 0.0365
Schistosoma mansoni steroid hormone receptor ad4bp 0.0137 0.0734 0.0769
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0071 0.0315 0.0378
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0063 0.0037
Echinococcus granulosus cathepsin l1 0.0043 0.0133 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0137 0.0734 0.0932
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0191 0.1076 0.136
Echinococcus granulosus alpha 1A adrenergic receptor 0.0071 0.0315 0.0378
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0052 0.0192 0.0242
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Plasmodium falciparum cyclin 0.0032 0.0066 0.0082
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0248 0.1433 0.1815
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Loa Loa (eye worm) jmjC domain-containing protein 0.0104 0.0525 0.0657
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0365 0.0383
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Trichomonas vaginalis cyclins, putative 0.0027 0.0034 0.0041
Brugia malayi Glycosyl hydrolases family 31 protein 0.0133 0.0705 0.0895
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Echinococcus granulosus integrin alpha ps 0.0066 0.0284 0.0341
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0042 0.0129 0.0072
Echinococcus granulosus g protein coupled receptor 0.0071 0.0315 0.0378
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Brugia malayi nuclear hormone receptor 0.0137 0.0734 0.0932
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Schistosoma mansoni intermediate filament proteins 0.013 0.0688 0.072
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0248 0.1433 0.1502
Onchocerca volvulus 0.0067 0.0288 0.0421
Brugia malayi Dopamine receptor 0.0071 0.0315 0.0399
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Giardia lamblia Furin precursor putative serine protease 0.019 0.1066 0.1287
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0248 0.1433 0.1748
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0133 0.0167
Loa Loa (eye worm) hypothetical protein 0.0063 0.0261 0.0321
Loa Loa (eye worm) G-protein coupled receptor 0.0071 0.0315 0.039
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0206 0.1168 0.1485
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0042 0.0129 0.0085
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0248 0.1433 0.1823
Brugia malayi hypothetical protein 0.0065 0.0274 0.0346
Leishmania major cathepsin L-like protease 0.0162 0.0891 0.1096
Plasmodium vivax JmjC domain containing protein 0.0027 0.0034 0.004
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0248 0.1433 0.1823
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0022 0.0002 0.0002
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0245 0.0234
Brugia malayi endoprotease bli-4 precursor 0.0981 0.6082 0.7741
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0078
Giardia lamblia Pyruvate kinase 0.0033 0.0073 0.0013
Loa Loa (eye worm) hypothetical protein 0.0046 0.0155 0.0186
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0155 0.0119
Onchocerca volvulus 0.0043 0.0133 0.0153
Trypanosoma brucei proteasome beta 7 subunit 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0044
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0581 0.0697
Onchocerca volvulus Protein ultraspiracle homolog 0.0137 0.0734 0.1187
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0042 0.0129 0.0085
Schistosoma mansoni zinc finger protein 0.0065 0.0274 0.0287
Plasmodium vivax proteasome subunit beta type-6, putative 0.0248 0.1433 0.1823
Plasmodium falciparum cysteine proteinase falcipain 3 0.0043 0.0133 0.0167
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0067 0.0289 0.0303
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0208 0.1179 0.1432
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0248 0.1433 0.1433
Echinococcus granulosus geminin 0.0452 0.273 0.3274
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0121 0.0424
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Echinococcus multilocularis tar DNA binding protein 0.0191 0.1076 0.1076
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0064 0.0268 0.0281
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.023 0.1321 0.1384
Echinococcus multilocularis ecdysone induced protein 78C 0.0137 0.0734 0.0734
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0067 0.0289 0.0289
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0034 0.0031
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Echinococcus granulosus biogenic amine 5HT receptor 0.0071 0.0315 0.0378
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Leishmania major proteasome alpha 7 subunit, putative 0.0248 0.1433 0.179
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus granulosus hypothetical protein 0.0071 0.0315 0.0378
Giardia lamblia 20S proteasome alpha subunit 1 0.0248 0.1433 0.1759
Brugia malayi RE15519p 0.0071 0.0315 0.0399
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0039 0.011 0.0118
Brugia malayi Nuclear hormone receptor-like 1 0.0073 0.0323 0.0409
Mycobacterium ulcerans beta-lactamase 0.0079 0.0365 0.0388
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis mitogen activated protein kinase 3 0.0036 0.0093 0.0093
Trypanosoma brucei proteasome beta 6 subunit 0.098 0.6073 0.773
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0121 0.0152
Leishmania major proteasome beta-1 subunit, putative 0.0248 0.1433 0.179
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0248 0.1433 0.1807
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trypanosoma cruzi cysteine peptidase, putative 0.0162 0.0891 0.1132
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0155 0.0195
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0082 0.0024
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0068 0.0296 0.0375
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0056 0.0218 0.0275
Mycobacterium tuberculosis Conserved protein 0.0048 0.0167 0.0134
Schistosoma mansoni nuclear receptor nhr-48 0.0065 0.0274 0.0287
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0155 0.0119
Brugia malayi steroid hormone receptor 0.0137 0.0734 0.0932
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0063 0.0063
Echinococcus multilocularis histone lysine n methyltransferase setd8 0.0078 0.0358 0.0358
Echinococcus multilocularis calpain A 0.0067 0.0289 0.0289
Brugia malayi mbt repeat family protein 0.004 0.0116 0.0145
Echinococcus granulosus G protein coupled receptor 139 0.0071 0.0315 0.0378
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0071 0.0315 0.039
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.1433 0.1815
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0248 0.1433 0.1823
Plasmodium vivax proteasome subunit beta type-7, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0065
Schistosoma mansoni hypothetical protein 0.0041 0.0125 0.0131
Echinococcus multilocularis proteasome subunit alpha type 6 0.0248 0.1433 0.1433
Brugia malayi putative neuropeptide receptor NPR1 0.0071 0.0315 0.0399
Echinococcus multilocularis cathepsin L cysteine protease 0.0043 0.0133 0.0133
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0065 0.0274 0.0274
Plasmodium falciparum subtilisin-like protease 2 0.0042 0.0129 0.0161
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Echinococcus granulosus proteasome subunit beta type 6 0.0248 0.1433 0.1719
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0065 0.0274 0.0396
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0034 0.0082 0.12
Loa Loa (eye worm) hypothetical protein 0.0035 0.0082 0.0093
Entamoeba histolytica proteasome subunit beta type 1, putative 0.098 0.6073 0.773
Onchocerca volvulus 0.013 0.0688 0.1108
Echinococcus multilocularis leukotriene A 4 hydrolase 0.023 0.1321 0.1321
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Plasmodium vivax hypothetical protein, conserved 0.0039 0.011 0.0137
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0121 0.0121
Giardia lamblia Fructose-bisphosphate aldolase 0.0238 0.1373 0.1681
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Brugia malayi hypothetical protein 0.0073 0.0323 0.0409
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0042 0.0129 0.0154
Echinococcus multilocularis musashi 0.013 0.0688 0.0688
Toxoplasma gondii subtilisin SUB5 0.0042 0.0129 0.0142
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0067 0.0289 0.0303
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0063 0.0078
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0042 0.0129 0.0085
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trichomonas vaginalis cyclin B, putative 0.0032 0.0066 0.0082
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0052 0.0192 0.0192
Brugia malayi hypothetical protein 0.015 0.0813 0.1033
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0129 0.0161
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0034 0.0035
Plasmodium falciparum subtilisin-like protease 1 0.0042 0.0129 0.0161
Onchocerca volvulus 0.0067 0.0288 0.0421
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0365 0.0365
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0071 0.0315 0.033
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.005 0.0061
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0248 0.1433 0.1823
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0137 0.0734 0.0932
Plasmodium falciparum thioredoxin reductase 0.0032 0.0063 0.0078
Brugia malayi nuclear receptor RXR 0.0073 0.0323 0.0409
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0167 0.0134
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0039 0.011 0.0137
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Brugia malayi hypothetical protein 0.0106 0.0533 0.0677
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0043 0.0133 0.0167
Schistosoma mansoni c4b-binding protein beta chain 0.0067 0.0288 0.0302
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0248 0.1433 0.1823
Onchocerca volvulus 0.0071 0.0315 0.0467
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0131 0.0692 0.0879
Schistosoma mansoni pyruvate kinase 0.0033 0.0073 0.0076
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0029 0.005 0.0052
Echinococcus granulosus lamin dm0 0.013 0.0688 0.0825
Mycobacterium ulcerans hypothetical protein 0.0108 0.0551 0.0626
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0039 0.011 0.011
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0365 0.0462
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0248 0.1433 0.1502
Toxoplasma gondii heat shock protein hslv, putative 0.0248 0.1433 0.1807
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.005 0.0061
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus granulosus microtubule associated protein 2 0.1337 0.8338 1
Onchocerca volvulus 0.0043 0.0133 0.0153
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0036 0.0093 0.0116
Plasmodium falciparum glutathione reductase 0.0032 0.0063 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Brugia malayi nuclear hormone receptor 0.0065 0.0274 0.0346
Brugia malayi Nuclear hormone receptor E75 0.0065 0.0274 0.0346
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0137 0.0734 0.0769
Trypanosoma cruzi subtilisin peptidase 0.0042 0.0129 0.0161
Echinococcus granulosus cysteine protease 0.0022 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0078 0.0358 0.0444
Mycobacterium ulcerans hypothetical protein 0.0048 0.0167 0.0134
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0245 0.0245
Toxoplasma gondii proteasome subunit beta type, putative 0.1261 0.7856 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0052 0.0192 0.0242
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0071 0.0315 0.033
Echinococcus multilocularis pyruvate kinase 0.0026 0.0029 0.0029
Onchocerca volvulus 0.0065 0.0274 0.0396
Loa Loa (eye worm) calpain family protein 1 0.0064 0.0268 0.033
Echinococcus multilocularis proteasome subunit beta type 7 0.0248 0.1433 0.1433
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0248 0.1433 0.1502
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.098 0.6073 0.773
Toxoplasma gondii subtilisin SUB8 0.0042 0.0129 0.0142
Giardia lamblia Proteasome subunit beta type 2 0.0607 0.3711 0.4681
Echinococcus granulosus leukotriene A 4 hydrolase 0.023 0.1321 0.1584
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni adenoreceptor 0.0071 0.0315 0.033
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0071 0.0315 0.0315
Echinococcus multilocularis FTZ F1 alpha 0.0137 0.0734 0.0734
Loa Loa (eye worm) thioredoxin reductase 0.0091 0.044 0.0549
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0114 0.0588 0.0705
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Trichomonas vaginalis maltase-glucoamylase, putative 0.0029 0.005 0.0061
Toxoplasma gondii proteasome beta subunit 0.0248 0.1433 0.1807
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) leukotriene A4 hydrolase 0.023 0.1321 0.1672
Brugia malayi hypothetical protein 0.0446 0.2688 0.342
Schistosoma mansoni cyclin B3 0.0032 0.0066 0.0069
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0131 0.0692 0.087
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0248 0.1433 0.1502
Schistosoma mansoni cpg binding protein 0.0063 0.0263 0.0275
Loa Loa (eye worm) hypothetical protein 0.0051 0.0188 0.0228
Loa Loa (eye worm) hypothetical protein 0.0128 0.0673 0.0845
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) glutathione reductase 0.0091 0.044 0.0549
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0206 0.1168 0.1485
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0063 0.0078
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0596 0.3642 0.3642
Loa Loa (eye worm) hypothetical protein 0.0122 0.0639 0.0803
Mycobacterium ulcerans proteasome PrcB 0.1261 0.7856 1
Loa Loa (eye worm) hypothetical protein 0.0446 0.2688 0.3413
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Brugia malayi Zona pellucida-like domain containing protein 0.0039 0.011 0.0137
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0039 0.011 0.0128
Schistosoma mansoni alpha glucosidase 0.0029 0.005 0.0052
Treponema pallidum 76K protein 0.0039 0.011 0.0357
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni tar DNA-binding protein 0.0191 0.1076 0.1128
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0581 0.0581
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0043 0.0133 0.0133
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Echinococcus granulosus 7tm_1 domain containing protein 0.0071 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0071 0.0315 0.0315
Schistosoma mansoni neuropeptide receptor 0.0071 0.0315 0.033
Loa Loa (eye worm) hypothetical protein 0.0082 0.0381 0.0474
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0607 0.3711 0.4712
Entamoeba histolytica hypothetical protein, conserved 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0248 0.1433 0.1807
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0037
Schistosoma mansoni hypothetical protein 0.0091 0.0439 0.046
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0248 0.1433 0.1759
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0248 0.1433 0.1823
Toxoplasma gondii histone lysine methyltransferase SET8 0.0078 0.0358 0.0435
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0042 0.0129 0.0085
Loa Loa (eye worm) hypothetical protein 0.0079 0.0365 0.0454
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0071 0.0315 0.033
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.004 0.0116 0.0145
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0365 0.0462
Echinococcus multilocularis neuroendocrine convertase 2 0.0617 0.3771 0.3771
Echinococcus granulosus dro:myosuppressin receptor 0.0071 0.0315 0.0378
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0137 0.0734 0.0932
Echinococcus granulosus g-protein coupled receptor 0.0071 0.0315 0.0378
Giardia lamblia 20S proteasome alpha subunit 4 0.0248 0.1433 0.1759
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus multilocularis orexin receptor type 2 0.0071 0.0315 0.0315
Echinococcus granulosus g protein coupled receptor 0.0071 0.0315 0.0378
Trypanosoma brucei proteasome subunit beta type-5, putative 0.1261 0.7856 1
Giardia lamblia High cysteine membrane protein Group 2 0.0365 0.2174 0.2709
Echinococcus granulosus intermediate filament protein 0.013 0.0688 0.0825
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0248 0.1433 0.1759
Mycobacterium tuberculosis Probable dehydrogenase 0.0208 0.1179 0.1432
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0167 0.021
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Echinococcus granulosus ecdysone induced protein 78C 0.0137 0.0734 0.088
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0034 0.004
Loa Loa (eye worm) TYRA-2 protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.015 0.0813 0.1025
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0248 0.1433 0.1823
Loa Loa (eye worm) hypothetical protein 0.004 0.0116 0.0135
Brugia malayi Tachykinin-like peptides receptor 99D 0.0071 0.0315 0.0399
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0039 0.011 0.0137
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Schistosoma mansoni biogenic amine (5HT) receptor 0.0071 0.0315 0.033
Echinococcus multilocularis neutral alpha glucosidase AB 0.0029 0.005 0.005
Brugia malayi Cathepsin L-like precursor 0.0043 0.0133 0.0167
Brugia malayi larval opioid receptor 0.0071 0.0315 0.0399
Onchocerca volvulus Huntingtin homolog 0.0081 0.0379 0.0576
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0067 0.0288 0.0356
Brugia malayi Serotonin receptor 0.0071 0.0315 0.0399
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.004 0.0116 0.0145
Echinococcus granulosus Nuclear hormone receptor HR96 0.0065 0.0274 0.0328
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0137 0.0734 0.0932
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0071 0.0315 0.033
Echinococcus multilocularis polycomb protein SCMH1 0.004 0.0116 0.0116
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0708 0.0742
Leishmania major proteasome beta 5 subunit, putative 0.1261 0.7856 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0137 0.0734 0.0769
Brugia malayi Probable ClpP-like protease 0.0056 0.0218 0.0275
Loa Loa (eye worm) hypothetical protein 0.0052 0.0192 0.0232
Echinococcus multilocularis pyruvate kinase 0.0033 0.0073 0.0073
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0248 0.1433 0.1823
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0167 0.0134
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0039 0.011 0.0115
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0031
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0052 0.0192 0.0192
Brugia malayi nuclear receptor NHR-67 0.0065 0.0274 0.0346
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0248 0.1433 0.1823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0365 0.0388
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0137 0.0734 0.0769
Schistosoma mansoni biogenic amine receptor 0.0071 0.0315 0.033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Plasmodium vivax subtilisin-like protease 1 0.0042 0.0129 0.0161
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0121 0.0075
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Onchocerca volvulus 0.0122 0.0639 0.1024
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0137 0.0734 0.0932
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0137 0.0734 0.088
Echinococcus granulosus neutral alpha glucosidase AB 0.0029 0.005 0.006
Schistosoma mansoni ap endonuclease 0.0041 0.0121 0.0127
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0232 0.1332 0.1693
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0037 0.0096 0.0029
Loa Loa (eye worm) hypothetical protein 0.0067 0.0288 0.0356
Onchocerca volvulus 0.0067 0.0288 0.0421
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0137 0.0734 0.0932
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Brugia malayi mbt repeat family protein 0.004 0.0116 0.0145
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0121 0.0152
Loa Loa (eye worm) hypothetical protein 0.0046 0.0155 0.0186
Echinococcus granulosus cathepsin l1 0.0028 0.0044 0.0052
Onchocerca volvulus 0.0042 0.0129 0.0146
Echinococcus granulosus peptide allatostatin:somatostatin 0.0071 0.0315 0.0378
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0045 0.015 0.0189
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Loa Loa (eye worm) beta-lactamase 0.0079 0.0365 0.0454
Echinococcus granulosus cyclins 0.0032 0.0066 0.0079
Schistosoma mansoni hypothetical protein 0.0032 0.0065 0.0068
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Toxoplasma gondii subtilisin SUB10 0.0042 0.0129 0.0142
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0063 0.0078
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.1131
Onchocerca volvulus 0.0071 0.0315 0.0467
Leishmania major proteasome beta 3 subunit, putative 0.0248 0.1433 0.179
Echinococcus multilocularis G-protein coupled receptor, putative 0.0071 0.0315 0.0315
Onchocerca volvulus 0.0071 0.0315 0.0467
Echinococcus granulosus polycomb protein SCMH1 0.004 0.0116 0.0139
Echinococcus multilocularis ubiquitin specific protease 41 0.0052 0.0192 0.0192
Leishmania major cathepsin L-like protease 0.0162 0.0891 0.1096
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0043 0.0133 0.0167
Onchocerca volvulus 0.0071 0.0315 0.0467
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0248 0.1433 0.1823
Brugia malayi MAP kinase sur-1 0.0036 0.0093 0.0116
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0039 0.011 0.0137
Brugia malayi Cyclin, N-terminal domain containing protein 0.0051 0.0188 0.0237
Trichomonas vaginalis cyclin D, putative 0.0032 0.0066 0.0082
Echinococcus granulosus beta-adrenergic receptor kinase 0.0109 0.0557 0.0668
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0036 0.0093 0.0116
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0071 0.0315 0.0467
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0162 0.0891 0.1132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0063 0.0078
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0052 0.0192 0.0242
Loa Loa (eye worm) nuclear hormone receptor 0.0065 0.0274 0.0337
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0248 0.1433 0.1502
Plasmodium falciparum apical sushi protein 0.0067 0.0288 0.0365
Onchocerca volvulus 0.0045 0.0148 0.0179
Plasmodium vivax vivapain-2 0.0043 0.0133 0.0167
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0093 0.0116
Schistosoma mansoni growth hormone secretagogue receptor 0.0071 0.0315 0.033
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0248 0.1433 0.1759
Onchocerca volvulus 0.0946 0.5858 1
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.019 0.1066 0.1355
Echinococcus multilocularis tumor protein p63 0.0213 0.1213 0.1213
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0121 0.0152
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0248 0.1433 0.1823
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0365 0.0388
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0365 0.0462
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0071 0.0315 0.039
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0041 0.0125 0.015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Toxoplasma gondii subtilisin SUB2 0.0042 0.0129 0.0142
Schistosoma mansoni hypothetical protein 0.0113 0.0581 0.0609
Onchocerca volvulus 0.0039 0.011 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0296 0.031
Echinococcus multilocularis lamin dm0 0.013 0.0688 0.0688
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Toxoplasma gondii hypothetical protein 0.0033 0.0074 0.0072
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0137 0.0734 0.0769
Echinococcus granulosus Furin 1 0.0232 0.1332 0.1597
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0596 0.3642 0.4369
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0063 0.0078
Echinococcus multilocularis somatostatin receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis pyruvate kinase 0.0033 0.0073 0.0073
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0137 0.0734 0.0769
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0048 0.0167 0.0134
Schistosoma mansoni site-1 peptidase (S08 family) 0.0042 0.0129 0.0135
Echinococcus granulosus protein will die slowly 0.0283 0.1657 0.1987
Brugia malayi celfurPC protein 0.0791 0.4879 0.621
Loa Loa (eye worm) cyclin domain-containing protein 0.0032 0.0066 0.0073
Echinococcus granulosus peptidase Clp S14 family 0.0037 0.0096 0.0115
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0023 0.0028
Trypanosoma cruzi cyclin, putative 0.0051 0.0188 0.0237
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0248 0.1433 0.1823
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0071 0.0315 0.0399
Trypanosoma brucei mitotic cyclin 6 0.0051 0.0188 0.0237
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.1433 0.1823
Giardia lamblia 20S proteasome alpha subunit 2 0.0248 0.1433 0.1759
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0071 0.0315 0.0399
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0137 0.0734 0.088
Onchocerca volvulus 0.0067 0.0288 0.0421
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1261 0.7856 1
Echinococcus multilocularis serotonin receptor 0.0071 0.0315 0.0315
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Echinococcus multilocularis allatostatin A receptor 0.0071 0.0315 0.0315
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0036 0.0093 0.0076
Brugia malayi CXXC zinc finger family protein 0.006 0.0241 0.0305
Loa Loa (eye worm) hypothetical protein 0.0065 0.0274 0.0337
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0607 0.3711 0.3887
Schistosoma mansoni myelin transcription factor 1 myt1 0.0045 0.015 0.0158
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0248 0.1433 0.1823
Schistosoma mansoni cathepsin F (C01 family) 0.0043 0.0133 0.0139
Trypanosoma brucei trypanothione reductase 0.0091 0.044 0.0558
Echinococcus granulosus G protein coupled receptor kinase 1 0.0098 0.0485 0.0582
Trichomonas vaginalis cyclin B, putative 0.0051 0.0188 0.0237
Loa Loa (eye worm) proteasome subunit beta type 2 0.0607 0.3711 0.4717
Brugia malayi Calcitonin receptor-like protein seb-1 0.0131 0.0692 0.0879
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0248 0.1433 0.1807
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Loa Loa (eye worm) hypothetical protein 0.0137 0.0734 0.0923
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0365 0.0438
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0071 0.0315 0.0315
Echinococcus granulosus neuropeptide Y receptor 0.0071 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Mycobacterium tuberculosis 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 0.1162 0.7227 0.9194
Schistosoma mansoni hypothetical protein 0.0071 0.0315 0.033
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0155 0.0119
Toxoplasma gondii subtilisin SUB7 0.0042 0.0129 0.0142
Schistosoma mansoni neuropeptide F-like receptor 0.0071 0.0315 0.033
Trypanosoma brucei proteasome alpha 7 subunit 0.0248 0.1433 0.1823
Plasmodium falciparum proteasome subunit beta type-5 0.1261 0.7856 1
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0192 0.0242
Entamoeba histolytica hypothetical protein 0.0113 0.0581 0.0738
Echinococcus granulosus Proteasome subunit alpha type 7 0.0248 0.1433 0.1719
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0155 0.0119
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1528 0.9546 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0137 0.0734 0.0769
Leishmania major cathepsin L-like protease 0.0043 0.0133 0.0127
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0365 0.0376
Schistosoma mansoni nuclear receptor 0.0065 0.0274 0.0287
Toxoplasma gondii rhoptry neck protein RON9 0.0067 0.0288 0.0346
Echinococcus granulosus survival motor neuron protein 1 0.0446 0.2688 0.3223
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0073 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0071 0.0315 0.0378
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0071 0.0315 0.033
Brugia malayi Cathepsin L-like cysteine proteinase 0.0028 0.0044 0.0053
Loa Loa (eye worm) hypothetical protein 0.0039 0.011 0.0128
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0155 0.0195
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0248 0.1433 0.1823
Schistosoma mansoni retinoic acid receptor RXR 0.0137 0.0734 0.0769
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0248 0.1433 1
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0248 0.1433 0.1823
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0091 0.044 0.0484
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0065 0.0274 0.0396
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0034 0.0035
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0832 0.5133 0.6531
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.04
Loa Loa (eye worm) integrin alpha pat-2 0.0229 0.1312 0.166
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.004 0.0116 0.0121
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0065 0.0274 0.0274
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0734 0.0769
Trypanosoma cruzi hypothetical protein, conserved 0.0417 0.2505 0.3187
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0071 0.0315 0.033
Brugia malayi follicle stimulating hormone receptor 0.0547 0.3328 0.4235
Plasmodium vivax proteasome subunit beta type-1, putative 0.098 0.6073 0.773
Plasmodium vivax subtilisin-like protease 2, putative 0.0042 0.0129 0.0161
Schistosoma mansoni cathepsin F (C01 family) 0.0043 0.0133 0.0139
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0607 0.3711 0.4722
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0048 0.0167 0.0134
Loa Loa (eye worm) DR-78 0.0065 0.0274 0.0337
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0056 0.0218 0.0186
Echinococcus multilocularis g protein coupled receptor 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0981 0.6082 0.7739
Schistosoma mansoni amine GPCR 0.0071 0.0315 0.033
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0044 0.0053
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Onchocerca volvulus 0.0071 0.0315 0.0467
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0071 0.0315 0.033
Giardia lamblia Kinase, CMGC MAPK 0.0036 0.0093 0.0038
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.0199
Brugia malayi glutathione reductase 0.0091 0.044 0.0558
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0365 0.0462
Brugia malayi Intermediate filament tail domain containing protein 0.013 0.0688 0.0873
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Echinococcus multilocularis transcription factor Dp 1 0.0023 0.0009 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.0044 0.0053
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0071 0.0315 0.0315
Trypanosoma cruzi hypothetical protein, conserved 0.0417 0.2505 0.3187
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0032 0.0066 0.0079
Trichomonas vaginalis cyclins, putative 0.0051 0.0188 0.0237
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0248 0.1433 0.1433
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.003 0.0052 0.0054
Schistosoma mansoni alpha-1 adrenergic receptor 0.0071 0.0315 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0623 0.0772
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0248 0.1433 0.1823
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0365 0.0388
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0296 0.031
Echinococcus multilocularis cpg binding protein 0.0063 0.0263 0.0263
Echinococcus granulosus 7TM GPCR rhodopsin 0.0071 0.0315 0.0378
Brugia malayi hypothetical protein 0.0067 0.0288 0.0365
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0165 0.091 0.1092
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0073 0.0323 0.0387
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Plasmodium falciparum thrombospondin-related anonymous protein 0.0039 0.011 0.0137
Echinococcus multilocularis GPCR, family 2 0.0041 0.0125 0.0125
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0039 0.011 0.0137
Brugia malayi proprotein convertase 2 0.0617 0.3771 0.4799
Trichomonas vaginalis conserved hypothetical protein 0.019 0.1066 0.1355
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0056 0.0218 0.1183
Brugia malayi jmjC domain containing protein 0.0104 0.0525 0.0665
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0071 0.0315 0.039
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0071 0.0315 0.0378
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.019 0.1066 0.1355
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0206 0.1168 0.1485
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0481 0.061
Echinococcus granulosus neuropeptide Y receptor 0.0071 0.0315 0.0378
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0248 0.1433 0.1823
Echinococcus multilocularis neuropeptide Y receptor 0.0071 0.0315 0.0315
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0248 0.1433 0.1433
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0238 0.1373 0.1745
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0248 0.1433 0.1502
Plasmodium vivax subtilisin-like serine protease, putative 0.0042 0.0129 0.0161
Schistosoma mansoni jumonji domain containing protein 0.0101 0.0503 0.0527
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0248 0.1433 0.1823
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0248 0.1433 0.179
Mycobacterium ulcerans hypothetical protein 0.0048 0.0167 0.0134
Echinococcus multilocularis g protein coupled receptor 0.0071 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0063 0.0261 0.0313
Brugia malayi jmjC domain containing protein 0.0027 0.0034 0.004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0137 0.0734 0.088
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0137 0.0734 0.0932
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0248 0.1433 0.1815
Onchocerca volvulus 0.0067 0.0288 0.0421
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0167 0.021
Leishmania major proteasome beta 2 subunit, putative 0.0248 0.1433 0.179
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0165 0.091 0.091
Echinococcus multilocularis neuropeptides capa receptor 0.0071 0.0315 0.0315
Brugia malayi hypothetical protein 0.0071 0.0315 0.0399
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0734 0.0769
Echinococcus multilocularis cyclin b3 0.0032 0.0066 0.0066
Onchocerca volvulus 0.0079 0.0365 0.0553
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0133 0.0167
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0121 0.0075
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.007 0.0009
Brugia malayi beta-lactamase 0.0079 0.0365 0.0462
Brugia malayi nuclear receptor NHR-88 0.0065 0.0274 0.0346
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.005 0.0061
Echinococcus multilocularis lysine specific demethylase 5A 0.0101 0.0503 0.0503
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0042 0.0129 0.0085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0071 0.0315 0.0315
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0063 0.0078
Loa Loa (eye worm) hypothetical protein 0.0071 0.0315 0.039
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0245 0.0257
Plasmodium falciparum glutathione reductase 0.0091 0.044 0.0558
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.1348 0.1706
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0042 0.0129 0.0161
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0122 0.0639 0.067
Brugia malayi Integrin alpha pat-2 precursor 0.0148 0.0803 0.102
Echinococcus multilocularis neuropeptide receptor 0.0575 0.351 0.351
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0155 0.0106
Echinococcus multilocularis cyclins 0.0032 0.0066 0.0066
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0063 0.0078
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0506 0.3071 0.3861
Echinococcus multilocularis thyroid hormone receptor alpha 0.0137 0.0734 0.0734
Echinococcus granulosus neuropeptide receptor 0.0071 0.0315 0.0378
Brugia malayi von Willebrand factor type A domain containing protein 0.0039 0.011 0.0137
Loa Loa (eye worm) fibroinase 0.0043 0.0133 0.0157
Leishmania major pyruvate kinase 0.0033 0.0073 0.005
Schistosoma mansoni ap endonuclease 0.0041 0.0121 0.0127
Brugia malayi Proteasome subunit alpha type 7-1 0.0248 0.1433 0.1823
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0065 0.0274 0.0274
Schistosoma mansoni furin-1 (S08 family) 0.0427 0.2568 0.269

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1500 nM Compounds were tested for their concentration to inhibit the HIV-1 Protease ChEMBL. 8423599
IC50 (binding) = 1500 nM Compounds were tested for their concentration to inhibit the HIV-1 Protease ChEMBL. 8423599

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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