Detailed information for compound 1631246

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1667.68 | Formula: C77H97Cl2N9O24S2
  • H donors: 19 H acceptors: 18 LogP: 2.55 Rotable bonds: 27
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCCCCCSSCCN[C@@]1(C)C[C@H](O[C@@H]2[C@H](O[C@H]([C@@H]([C@@H]2O)O)CO)Oc2c3cc4cc2Oc2ccc(cc2Cl)[C@@H](O)[C@@H]2NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(=O)N)NC(=O)[C@@H]([C@@H](c4ccc(O3)c(Cl)c4)O)NC(=O)[C@@H](CC(C)C)NC)c3ccc(c(c3)c3c(O)cc(cc3[C@H](NC2=O)C(=O)O)O)O)O[C@@H]([C@H]1O)C
  • InChi: 1S/C77H97Cl2N9O24S2/c1-7-8-9-10-11-12-13-21-113-114-22-20-82-77(5)32-55(107-35(4)68(77)98)111-67-65(97)64(96)53(33-89)110-76(67)112-66-51-27-39-28-52(66)109-50-19-16-38(26-44(50)79)63(95)61-74(104)86-59(75(105)106)42-29-40(90)30-48(92)56(42)41-24-36(14-17-47(41)91)57(71(101)88-61)85-72(102)58(39)84-70(100)46(31-54(80)93)83-73(103)60(87-69(99)45(81-6)23-34(2)3)62(94)37-15-18-49(108-51)43(78)25-37/h14-19,24-30,34-35,45-46,53,55,57-65,67-68,76,81-82,89-92,94-98H,7-13,20-23,31-33H2,1-6H3,(H2,80,93)(H,83,103)(H,84,100)(H,85,102)(H,86,104)(H,87,99)(H,88,101)(H,105,106)/t35-,45-,46+,53+,55+,57-,58-,59+,60-,61+,62-,63-,64+,65+,67+,68-,76-,77+/m1/s1
  • InChiKey: DZAPLBLBWJUNLE-JJJXSFMDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0061 0.0091 0.011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0053 0.0053
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0019 0.0018 0.0024
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0064 0.0064
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0135 0.0223 0.0223
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.001 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0131 0.0131
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0018 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0977 0.1724 0.1724
Entamoeba histolytica hypothetical protein 0.029 0.05 0.067
Onchocerca volvulus 0.0135 0.0223 0.0221
Onchocerca volvulus 0.0014 0.0009 0.0006
Echinococcus granulosus peptidyl prolyl cis trans isomerase 1 0.0014 0.0009 0.0009
Leishmania major endonuclease/exonuclease protein-like protein 0.0019 0.0018 0.0012
Echinococcus multilocularis GPCR, family 2 0.008 0.0126 0.0126
Trichomonas vaginalis peptidyl-prolyl cis-trans isomerase A, ppia, putative 0.0014 0.0009 0.0012
Schistosoma mansoni neutral sphingomyelinase 0.0019 0.0018 0.0018
Leishmania major hypothetical protein, conserved 0.0019 0.0018 0.0012
Brugia malayi Cathepsin L-like precursor 0.0016 0.0012 0.0011
Echinococcus granulosus survival motor neuron protein 1 0.0977 0.1724 0.1724
Loa Loa (eye worm) hypothetical protein 0.0174 0.0292 0.0292
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0063 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0419 0.073 0.073
Echinococcus multilocularis peptidyl prolyl cis trans isomerase E 0.0014 0.0009 0.0009
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0053 0.0053
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0071 0.011 0.011
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0068 0.0104 0.9454
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0012 0.0016
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0012 0.0012
Echinococcus multilocularis muscleblind protein 0.0152 0.0254 0.0254
Echinococcus granulosus peptidyl prolyl cis trans isomerase E 0.0014 0.0009 0.0009
Echinococcus multilocularis pyruvate kinase 0.0066 0.0101 0.0101
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0019 0.0018 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.001 0.0014
Echinococcus multilocularis peptidyl prolyl cis trans isomerase 2 0.0014 0.0009 0.0009
Giardia lamblia Inositol 5-phosphatase 4 0.0019 0.0018 0.0024
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.0439 0.0438
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0015
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0017
Giardia lamblia Rrm3p helicase 0.4201 0.7467 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0003 0.0003
Leishmania major importin beta-1 subunit, putative 0.0025 0.0027 0.0024
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0091 0.0122
Schistosoma mansoni hypothetical protein 0.008 0.0126 0.0126
Schistosoma mansoni hypothetical protein 0.0417 0.0726 0.0726
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0003 0.0002
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase G ppig 0.0014 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0036
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0054 0.0054
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0018 0.0015 0.0015
Loa Loa (eye worm) MH2 domain-containing protein 0.0358 0.0621 0.0621
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-12, Bmcyp-12 0.0014 0.0009 0.0008
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-15, Bmcyp-5 0.0014 0.0009 0.0008
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0018 0.0015 0.0015
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0018 0.0015 0.0015
Giardia lamblia Kinase, CMGC MAPK 0.0061 0.0091 0.0122
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0126 0.0126
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0053 0.0052
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0019 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0083 0.0131 0.0131
Echinococcus granulosus Polycystic kidney disease protein 0.5622 1 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0018 0.0012
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0204 0.0204
Toxoplasma gondii U-snRNP-associated cyclophilin family protein 0.0014 0.0009 0.0568
Loa Loa (eye worm) ctsf protein 0.0016 0.0012 0.0012
Toxoplasma gondii cyclophilin 1, putative 0.0014 0.0009 0.0568
Trichomonas vaginalis set domain proteins, putative 0.0241 0.0412 0.0552
Toxoplasma gondii peptidyl-prolyl isomerase 0.0014 0.0009 0.0568
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0019 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0018 0.0015 0.0015
Echinococcus multilocularis deoxyribonuclease 1 2 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0083 0.0131 0.0131
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0083 0.0131 0.0131
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0064 0.0074
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.0252 0.0326
Trypanosoma cruzi mitochondrial protein 99, putative 0.0019 0.0018 0.0012
Echinococcus granulosus FTZ F1 alpha 0.0083 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0083 0.0131 0.0131
Brugia malayi latrophilin 2 splice variant baaae 0.0174 0.0292 0.0291
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0038 0.0038
Leishmania major cathepsin L-like protease 0.0016 0.0012 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Echinococcus multilocularis expressed protein 0.0014 0.0009 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0091 0.0122
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Loa Loa (eye worm) hypothetical protein 0.0088 0.014 0.014
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0419 0.073 0.0729
Trichomonas vaginalis peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0012
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0037 0.2414
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.001 0.001
Leishmania major GTP-binding protein, putative 0.0022 0.0023 0.0019
Toxoplasma gondii cyclophilin precursor 0.0014 0.0009 0.0568
Mycobacterium tuberculosis Probable exported protein 0.0019 0.0018 0.0112
Echinococcus multilocularis peptidylprolyl isomerase domain and WD40 repeat 0.0014 0.0009 0.0009
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0018 0.0015 0.002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0044 0.0061 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0054 0.0072
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.011 0.1289
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0009
Schistosoma mansoni cyclophilin 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Echinococcus multilocularis inositol monophosphatase 1 0.0076 0.0119 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0131 0.0131
Echinococcus granulosus expressed protein 0.0018 0.0015 0.0015
Brugia malayi ecdysteroid receptor 0.0083 0.0131 0.013
Brugia malayi RNA binding protein 0.0127 0.0209 0.0208
Echinococcus granulosus mothers against decapentaplegic 6 0.0011 0.0002 0.0002
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0325 0.0561 0.0561
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0018 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0019 0.0018 0.0012
Echinococcus multilocularis thyroid hormone receptor alpha 0.0207 0.0351 0.0351
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0019 0.0018 0.0012
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0126 0.0126
Schistosoma mansoni RAR-like nuclear receptor 0.0083 0.0131 0.0131
Onchocerca volvulus 0.0019 0.0018 0.0015
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0019 0.0018 0.0012
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0126 0.0126
Schistosoma mansoni cpg binding protein 0.0029 0.0035 0.0035
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0044 0.0061 0.0061
Brugia malayi Isocitrate dehydrogenase 0.0015 0.001 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0282 0.0378
Giardia lamblia Peptidyl-prolyl cis-trans isomerase B precursor 0.0014 0.0009 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0047 0.0063
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.011 0.1289
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0054 0.0072
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.011 0.0147
Schistosoma mansoni steroid hormone receptor ad4bp 0.0083 0.0131 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0061 0.0091 0.011
Loa Loa (eye worm) cytosolic cyclophilin 0.0014 0.0009 0.0009
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0096 0.0154 0.0154
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0088 0.0139 0.0186
Schistosoma mansoni coup transcription factor 0.0083 0.0131 0.0131
Brugia malayi steroid hormone receptor 0.0083 0.0131 0.013
Schistosoma mansoni hypothetical protein 0.4201 0.7467 0.7467
Echinococcus granulosus neuropeptide s receptor 0.0474 0.0828 0.0828
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0002
Onchocerca volvulus 0.0016 0.0012 0.001
Onchocerca volvulus 0.0016 0.0012 0.001
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0094 0.0114
Leishmania major cathepsin L-like protease 0.0062 0.0094 0.0114
Brugia malayi hypothetical protein 0.5622 1 1
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0019 0.0018 0.0018
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0053 0.0053
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.001 0.0009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0053 0.0053
Brugia malayi hypothetical protein 0.0308 0.0532 0.0531
Echinococcus multilocularis peptidyl prolyl cis trans isomerase 6 0.0014 0.0009 0.0009
Loa Loa (eye worm) inositol-1 0.0076 0.0119 0.0118
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0419 0.073 0.073
Toxoplasma gondii cyclophilin, putative 0.0014 0.0009 0.0568
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.001 0.001
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0019 0.0018 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.011 0.0136
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0419 0.073 0.073
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0012 0.0016
Echinococcus multilocularis dnaJ subfamily B 0.0417 0.0726 0.0726
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0083 0.0131 0.013
Mycobacterium tuberculosis Conserved hypothetical protein 0.0168 0.0282 0.3482
Brugia malayi mothers against decapentaplegic homolog 3 0.0011 0.0002 0.0002
Onchocerca volvulus 0.0016 0.0012 0.001
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0009
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0054 0.0054
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0096 0.0154 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.008 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Echinococcus multilocularis peptidyl prolyl cis trans isomerase 4 0.0014 0.0009 0.0009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0254 0.0435 0.0435
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0019 0.0018 0.0018
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0027 0.0036
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.4201 0.7467 1
Onchocerca volvulus 0.0016 0.0012 0.001
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0012 0.0012
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0101 0.0101
Schistosoma mansoni transcription factor LCR-F1 0.029 0.05 0.05
Trichomonas vaginalis peptidyl-prolyl cis-trans isomerase A, ppia, putative 0.0014 0.0009 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0005 0.0006
Onchocerca volvulus 0.0083 0.0131 0.0128
Brugia malayi nuclear hormone receptor 0.0083 0.0131 0.013
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0127 0.0209 0.0209
Schistosoma mansoni Smad4 0.0024 0.0026 0.0026
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.1139
Trichomonas vaginalis cyclophilin, putative 0.0014 0.0009 0.0012
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-16, Bmcyp-16 0.0014 0.0009 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0012 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0091 0.0122
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0061 0.0091 0.5904
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.0018 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0026 0.0026
Brugia malayi MH1 domain containing protein 0.0013 0.0007 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.0024
Loa Loa (eye worm) hypothetical protein 0.0066 0.0101 0.0101
Brugia malayi beta-lactamase family protein 0.0071 0.011 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.036 0.036
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.0018 0.0012
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0063 0.0072
Loa Loa (eye worm) doublecortin family protein 0.5622 1 1
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0018 0.0015 0.0015
Echinococcus multilocularis ecdysone induced protein 78C 0.0083 0.0131 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0083 0.0131 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0052 0.007
Brugia malayi conserved hypotetical protein 0.0039 0.0053 0.0052
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0318 0.055 0.0726
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0282 0.0378
Echinococcus multilocularis lamin dm0 0.0135 0.0223 0.0223
Plasmodium vivax cyclophilin, putative 0.0014 0.0009 0.0009
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0419 0.073 0.073
Loa Loa (eye worm) hypothetical protein 0.0071 0.011 0.011
Loa Loa (eye worm) beta-lactamase 0.0071 0.011 0.011
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0209 0.0209
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.001 0.0002
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0018 0.0015 0.0015
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0023 0.0019
Brugia malayi CCR4 0.002 0.0018 0.0017
Trichomonas vaginalis peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0012
Brugia malayi nuclear receptor NHR-88 0.0039 0.0053 0.0052
Echinococcus multilocularis lipoxygenase domain containing protein 0.5622 1 1
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0018 0.0015 0.0015
Echinococcus granulosus peptidyl prolyl isomerase G 0.0014 0.0009 0.0009
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0018 0.0015 0.002
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0088 0.0139 0.9035
Plasmodium vivax SET domain protein, putative 0.0031 0.0038 0.0038
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0012
Mycobacterium tuberculosis Conserved protein 0.0071 0.011 0.1289
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0012 0.0016
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0094 0.0114
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.1139
Plasmodium vivax peptidyl-prolyl cis-trans isomerase 11, putative 0.0014 0.0009 0.0009
Trypanosoma brucei pyruvate kinase 1 0.0066 0.0101 0.0124
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.011 0.0109
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0038 0.2472
Loa Loa (eye worm) fibroinase 0.0016 0.0012 0.0012
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0101 0.0101
Echinococcus granulosus GPCR family 2 0.008 0.0126 0.0126
Brugia malayi Cathepsin L-like precursor 0.0016 0.0012 0.0011
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0019 0.0018 0.0018
Brugia malayi Cathepsin L-like precursor 0.0016 0.0012 0.0011
Onchocerca volvulus 0.0135 0.0223 0.0221
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0061 0.0061
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0018 0.0017
Trypanosoma brucei pyruvate kinase 1, putative 0.0066 0.0101 0.0124
Echinococcus granulosus pyruvate kinase 0.0034 0.0044 0.0044
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0251 0.043 0.043
Loa Loa (eye worm) CYN-5 protein 0.0014 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0439 0.0587
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0091 0.0122
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0439 0.0587
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0053 0.0053
Onchocerca volvulus Putative neutral sphingomyelinase 0.0019 0.0018 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0031 0.0042
Echinococcus multilocularis tar DNA binding protein 0.0127 0.0209 0.0209
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-18, Bmcyp-18 0.0014 0.0009 0.0008
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0018 0.0015 0.0014
Loa Loa (eye worm) cyclophilin-type peptidyl-prolyl cis-trans isomerase-2 0.0014 0.0009 0.0009
Mycobacterium leprae Probable lipase LipE 0.0071 0.011 1
Echinococcus granulosus synaptojanin 1 0.0019 0.0018 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0061 0.006
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.0018 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.4201 0.7467 1
Schistosoma mansoni Smad4 0.0011 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0064 0.0085
Schistosoma mansoni ran 0.0022 0.0023 0.0023
Brugia malayi tailless protein 0.0039 0.0053 0.0052
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0012 0.0005
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0018 0.0015 0.0014
Onchocerca volvulus Protein ultraspiracle homolog 0.0083 0.0131 0.0128
Echinococcus multilocularis mitogen activated protein kinase 0.0061 0.0091 0.0091
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0018 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0071 0.011 0.011
Trichomonas vaginalis cyclophilin, putative 0.0014 0.0009 0.0012
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.0019 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0031 0.0041
Brugia malayi peptidyl-prolyl cis-trans isomerase 11 0.0014 0.0009 0.0008
Leishmania major RNA-editing complex protein MP100, putative 0.0019 0.0018 0.0012
Schistosoma mansoni carbon catabolite repressor protein 0.0019 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0037 0.005
Onchocerca volvulus 0.0031 0.0038 0.0036
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0018 0.0015 0.0014
Entamoeba histolytica hypothetical protein 0.029 0.05 0.067
Echinococcus granulosus pyruvate kinase 0.0034 0.0044 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0053 0.0052
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0419 0.073 0.073
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.011 0.011
Echinococcus multilocularis peptidyl prolyl cis trans isomerase B 0.0014 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Echinococcus granulosus mitogen activated protein kinase 3 0.0061 0.0091 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0083 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0063 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0007
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0018 0.0017
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0053 0.0053
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase-like 2 ppil2 0.0014 0.0009 0.0009
Mycobacterium tuberculosis Conserved protein 0.0071 0.011 0.1289
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.0252 0.0326
Echinococcus multilocularis FTZ F1 alpha 0.0083 0.0131 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0003 0.0003
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0009
Toxoplasma gondii peptidylprolyl isomerase domain-containing protein 0.0014 0.0009 0.0568
Echinococcus granulosus cathepsin l1 0.0016 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0054 0.0072
Trichomonas vaginalis ran, putative 0.0022 0.0023 0.0031
Brugia malayi hypothetical protein 0.0039 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.0083 0.0131 0.0131
Plasmodium vivax cyclophilin, putative 0.0014 0.0009 0.0009
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0019 0.0018 0.0024
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.0439 0.0439
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Echinococcus multilocularis Smad4 0.0024 0.0026 0.0026
Plasmodium vivax cyclophilin, putative 0.0014 0.0009 0.0009
Brugia malayi Pre-SET motif family protein 0.0031 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0044 0.0061 0.0061
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.001 0.001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0119 0.0147
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase family 1 0.0014 0.0009 0.0568
Trichomonas vaginalis Phospholipase C precursor, putative 0.0019 0.0018 0.0024
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0083 0.0131 0.0131
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.001 0.001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0064 0.0074
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0019 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0012 0.0016
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0023 0.0019
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0043 0.2799
Loa Loa (eye worm) DR-78 0.0039 0.0053 0.0053
Echinococcus multilocularis synaptojanin 1 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0037
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0096 0.0154 0.0154
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0083 0.0131 0.013
Brugia malayi Cathepsin L-like precursor 0.0016 0.0012 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0209 0.0209
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0018 0.0018
Brugia malayi Muscleblind-like protein 0.0152 0.0254 0.0253
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0026 0.0026
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0044 0.2842
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0012 0.0012
Leishmania major pyruvate kinase 0.0066 0.0101 0.0124
Trichomonas vaginalis bromodomain-containing protein, putative 0.0088 0.0139 0.0186
Loa Loa (eye worm) RNA binding protein 0.0127 0.0209 0.0209
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0047 0.0063
Plasmodium falciparum importin beta, putative 0.003 0.0037 0.0037
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0018 0.0015 0.0015
Echinococcus granulosus neuropeptide receptor A26 0.0474 0.0828 0.0828
Plasmodium falciparum pyruvate kinase 0.0066 0.0101 0.0101
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase G ppig 0.0014 0.0009 0.0009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0053 0.0053
Echinococcus multilocularis traf and tnf receptor associated protein 0.0019 0.0018 0.0018
Brugia malayi MH1 domain containing protein 0.0013 0.0007 0.0006
Schistosoma mansoni survival motor neuron protein 0.0199 0.0338 0.0338
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0083 0.0131 0.0128
Loa Loa (eye worm) cyclophilin-type peptidyl-prolyl cis-trans isomerase-18 0.0014 0.0009 0.0009
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.0018 0.0012
Onchocerca volvulus 0.0014 0.0009 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0000051633 0.0000069146
Plasmodium vivax hypothetical protein, conserved 0.0071 0.011 0.011
Schistosoma mansoni lamin 0.0135 0.0223 0.0223
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0076 0.0119 0.7693
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0036
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-13, Bmcyp-13 0.0014 0.0009 0.0008
Brugia malayi RNA recognition motif domain containing protein 0.0127 0.0209 0.0208
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0019 0.0018 0.0018
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0096 0.0154 0.0154
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0101 0.0101
Loa Loa (eye worm) glutaminase 0.0548 0.0959 0.0959
Brugia malayi hypothetical protein 0.0044 0.0061 0.006
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0054 0.006
Leishmania major hypothetical protein, conserved 0.0019 0.0018 0.0012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0083 0.0131 0.0131
Echinococcus granulosus inositol monophosphatase 1 0.0076 0.0119 0.0119
Echinococcus granulosus smad 0.0024 0.0026 0.0026
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0019 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0017
Onchocerca volvulus Huntingtin homolog 0.0374 0.0649 0.0646
Brugia malayi hypothetical protein 0.0977 0.1724 0.1724
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0012
Plasmodium vivax cyclophilin, putative 0.0014 0.0009 0.0009
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.001 0.001
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0037 0.0038
Echinococcus granulosus cathepsin l1 0.0011 0.0003 0.0003
Giardia lamblia Pyruvate kinase 0.0034 0.0044 0.0059
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0009
Trypanosoma brucei protein kinase, putative 0.0061 0.0091 0.011
Toxoplasma gondii cyclophilin 0.0014 0.0009 0.0568
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0096 0.0154 0.1852
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0096 0.0154 0.0154
Brugia malayi MAP kinase sur-1 0.0061 0.0091 0.009
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0015 0.002
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0026 0.0026
Brugia malayi glutaminase DH11.1 0.0548 0.0959 0.0958
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0131 0.013
Echinococcus multilocularis snurportin 1 0.0325 0.0561 0.0561
Brugia malayi intermediate filament protein 0.0135 0.0223 0.0222
Onchocerca volvulus 0.0018 0.0015 0.0013
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0072 0.0112 0.0112
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0019 0.0018 0.0012
Schistosoma mansoni microtubule-associated protein tau 0.2083 0.3695 0.3695
Loa Loa (eye worm) hypothetical protein 0.0044 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0015
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0026 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.011 0.0136
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.009 0.009
Onchocerca volvulus 0.0011 0.0003 0.0000086756
Schistosoma mansoni rab6-interacting 0.5622 1 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0012 0.0012
Toxoplasma gondii ABC1 family protein 0.0071 0.011 0.713
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0083 0.0131 0.0131
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0002
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.0024
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0318 0.055 0.0726
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0003 0.0003
Brugia malayi hypothetical protein 0.0374 0.0649 0.0648
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0054 0.006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.011 0.0147
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0012
Schistosoma mansoni inositol monophosphatase 0.0076 0.0119 0.0119
Brugia malayi MH1 domain containing protein 0.0024 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0199 0.0338 0.0338
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0101 0.0099
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0053 0.0053
Echinococcus granulosus lipoxygenase domain containing protein 0.5622 1 1
Leishmania major pantothenate kinase subunit, putative 0.0019 0.0018 0.0012
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0022
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0054 0.0072
Trichomonas vaginalis inositol monophosphatase, putative 0.0076 0.0119 0.0159
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0018 0.0015 0.0014
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0018 0.0015 0.0015
Schistosoma mansoni rab6-interacting 0.5622 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0131 0.0131
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Schistosoma mansoni smad1 5 8 and 0.0024 0.0026 0.0026
Leishmania major cathepsin L-like protease 0.0016 0.0012 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.0096 0.0154 0.0206
Toxoplasma gondii exonuclease III APE 0.0096 0.0154 1
Loa Loa (eye worm) SIG-7 protein 0.0014 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0012 0.0016
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0096 0.0154 0.0154
Loa Loa (eye worm) cysteine protease 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0083 0.0131 0.0131
Brugia malayi exodeoxyribonuclease III family protein 0.0096 0.0154 0.0153
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0061 0.0091 0.011
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0053 0.0053
Giardia lamblia GTOR 0.0045 0.0064 0.0085
Leishmania major mitochondrial DNA polymerase beta 0.0318 0.055 0.0726
Schistosoma mansoni hypothetical protein 0.0685 0.1203 0.1203
Echinococcus multilocularis mothers against decapentaplegic 2 0.0011 0.0002 0.0002
Brugia malayi G-protein alpha subunit 0.0018 0.0015 0.0014
Mycobacterium leprae conserved hypothetical protein 0.0071 0.011 1
Toxoplasma gondii hypothetical protein 0.0051 0.0075 0.4838
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0023 0.0019
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.1139
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.011 0.011
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0038 0.0038
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0455 0.0793 1
Trichomonas vaginalis glutaminase, putative 0.0548 0.0959 0.1284
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.4201 0.7467 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0083 0.0131 0.0131
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0064 0.0064
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0036
Loa Loa (eye worm) transcription factor SMAD2 0.0358 0.0621 0.0621
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0019 0.0018 0.0024
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0054 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0064 0.0074
Schistosoma mansoni lipoxygenase 0.5622 1 1
Entamoeba histolytica hypothetical protein 0.029 0.05 0.067
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0064 0.0074
Trichomonas vaginalis cyclophillin, putative 0.0014 0.0009 0.0012
Schistosoma mansoni smad1 5 8 and 0.0024 0.0026 0.0026
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0053 0.0053
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0053 0.0053
Echinococcus multilocularis lipoxygenase domain containing protein 0.5622 1 1
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Echinococcus granulosus microtubule associated protein 2 0.2083 0.3695 0.3695
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0419 0.073 0.073
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0047 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0058
Echinococcus multilocularis pyruvate kinase 0.0034 0.0044 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0058
Schistosoma mansoni nuclear receptor 0.0039 0.0053 0.0053
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0568
Onchocerca volvulus 0.0016 0.0012 0.001
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0026 0.0026
Mycobacterium ulcerans glutaminase 0.0548 0.0959 1
Brugia malayi MH2 domain containing protein 0.0024 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.5622 1 1
Brugia malayi hypothetical protein 0.0025 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0374 0.0649 0.0648
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0044 0.0044
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0119 0.0159
Onchocerca volvulus 0.0016 0.0012 0.001
Trichomonas vaginalis cyclophilin, putative 0.0014 0.0009 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.009 0.0857
Echinococcus multilocularis neuropeptide receptor A26 0.0474 0.0828 0.0828
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0076 0.0119 0.1155
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0131 0.013
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0101 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0031 0.0042
Entamoeba histolytica cysteine protease, putative 0.0016 0.0012 0.0016
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.001 0.0002
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0096 0.0154 0.0206
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0063 0.0072
Echinococcus granulosus ecdysone induced protein 78C 0.0083 0.0131 0.0131
Brugia malayi Steroid receptor seven-up type 2 0.0083 0.0131 0.013
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0018 0.0017
Schistosoma mansoni importin beta-1 0.003 0.0037 0.0037
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0012 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0419 0.073 0.073
Brugia malayi hypothetical protein 0.0088 0.014 0.0139
Entamoeba histolytica pyruvate kinase, putative 0.0046 0.0066 0.0088
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0018 0.0015 0.0014
Trichomonas vaginalis ap endonuclease, putative 0.0096 0.0154 0.0206
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0019 0.0018 0.0024
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0031
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0027 0.0024
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0096 0.0154 0.1529
Loa Loa (eye worm) hypothetical protein 0.5622 1 1
Loa Loa (eye worm) pyruvate kinase-PB 0.0046 0.0066 0.0066
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0023 0.0023
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.009 0.009
Onchocerca volvulus 0.0029 0.0035 0.0033
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.4201 0.7467 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.001 0.0014
Plasmodium vivax exodeoxyribonuclease III, putative 0.0019 0.0018 0.0018
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0088 0.0139 0.0139
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.011 0.1064
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0012 0.0005
Echinococcus granulosus lipoxygenase domain containing protein 0.5622 1 1
Plasmodium falciparum DNase I-like protein, putative 0.0019 0.0018 0.0018
Echinococcus granulosus peptidylprolyl isomerase domain and WD40 repeat 0.0014 0.0009 0.0009
Echinococcus multilocularis cysteine protease 0.0016 0.0012 0.0012
Plasmodium falciparum histone acetyltransferase GCN5 0.008 0.0126 0.0126
Schistosoma mansoni lipoxygenase 0.0055 0.008 0.008
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase h ppih 0.0014 0.0009 0.0009
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.001 0.0673
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0439 0.0587
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.001 0.0002
Brugia malayi Inositol-1 0.0076 0.0119 0.0118
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Loa Loa (eye worm) hypothetical protein 0.0071 0.011 0.011
Onchocerca volvulus 0.0039 0.0053 0.005
Toxoplasma gondii cyclophilin, putative 0.0014 0.0009 0.0568
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0019 0.0018 0.0012
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0027 0.0036
Loa Loa (eye worm) cyclophilin Ovcyp-2 0.0014 0.0009 0.0009
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0083 0.0131 0.0131
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.008 0.008
Echinococcus granulosus mothers against decapentaplegic 2 0.0011 0.0002 0.0002
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0083 0.0131 0.0131
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.002 0.0018 0.0018
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0282 0.0378
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0012 0.0012
Schistosoma mansoni ap endonuclease 0.0096 0.0154 0.0154
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase-like 1 ppil1 0.0014 0.0009 0.0009
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Schistosoma mansoni cpg binding protein 0.0031 0.0038 0.0038
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0053 0.0053
Giardia lamblia Pyruvate kinase 0.0066 0.0101 0.0136
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0018 0.0017
Echinococcus granulosus importin subunit beta 1 0.003 0.0037 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0058
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0053 0.0053
Schistosoma mansoni smad1 5 8 and 0.0024 0.0026 0.0026
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0131 0.013
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0009
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.009 0.1038
Echinococcus granulosus muscleblind protein 0.0152 0.0254 0.0254
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0135 0.0223 0.0223
Brugia malayi hypothetical protein 0.5622 1 1
Loa Loa (eye worm) glutaminase 2 0.0548 0.0959 0.0959
Brugia malayi nuclear receptor NHR-88 0.0083 0.0131 0.013
Onchocerca volvulus 0.0071 0.011 0.0107
Plasmodium vivax multidomain scavenger receptor, putative 0.5622 1 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0083 0.0131 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Schistosoma mansoni hypothetical protein 0.0325 0.0561 0.0561
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.0018 0.0012
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0119 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.029 0.05 0.05
Plasmodium vivax pyruvate kinase, putative 0.0066 0.0101 0.0101
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0091 0.011
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0018 0.0017
Trichomonas vaginalis peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0012
Brugia malayi MH1 domain containing protein 0.0024 0.0026 0.0026
Toxoplasma gondii pyruvate kinase PyK1 0.0066 0.0101 0.6583
Plasmodium vivax vivapain-2 0.0016 0.0012 0.0012
Plasmodium vivax cyclophilin, putative 0.0014 0.0009 0.0009
Echinococcus granulosus peptidyl prolyl cis trans isomerase CWC27 0.0014 0.0009 0.0009
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0054 0.0054
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.1139
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0254 0.0254
Schistosoma mansoni thyroid hormone receptor 0.0207 0.0351 0.0351
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0018 0.0015 0.0015
Schistosoma mansoni lamin 0.0135 0.0223 0.0223
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0018 0.0015 0.0014
Echinococcus granulosus peptidyl prolyl cis trans isomerase 6 0.0014 0.0009 0.0009
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.0024
Echinococcus granulosus lamin dm0 0.0135 0.0223 0.0223
Chlamydia trachomatis pyruvate kinase 0.0066 0.0101 0.5
Leishmania major cathepsin L-like protease 0.0016 0.0012 0.0005
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.001 0.0002
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0119 0.0147
Schistosoma mansoni nuclear hormone receptor 0.0083 0.0131 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0091 0.0091
Echinococcus multilocularis microtubule associated protein 2 0.2083 0.3695 0.3695
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0017
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0035 0.0035
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0018 0.0017
Entamoeba histolytica hypothetical protein 0.029 0.05 0.067
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0027 0.0025
Schistosoma mansoni smad 0.0011 0.0002 0.0002
Onchocerca volvulus 0.0018 0.0015 0.0013
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0063 0.0095 0.0095
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0096 0.0154 0.0195
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0419 0.073 0.073
Echinococcus multilocularis Polycystic kidney disease protein 0.5622 1 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0035 0.0035
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0018 0.0015 0.0015
Schistosoma mansoni cyclophilin E 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0015
Brugia malayi Latrophilin receptor protein 2 0.008 0.0126 0.0125
Schistosoma mansoni zinc finger protein 0.0039 0.0053 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0298 0.0399
Echinococcus multilocularis survival motor neuron protein 1 0.0977 0.1724 0.1724
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0096 0.0096
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0053 0.0053
Brugia malayi cathepsin L-like precursor 0.0011 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Loa Loa (eye worm) hypothetical protein 0.0044 0.0061 0.0061
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0019 0.0018 0.0018
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0019 0.0018 0.0024
Brugia malayi hypothetical protein 0.0044 0.0061 0.006
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0064 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0083 0.0131 0.0131
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0054 0.0054
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0026 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0036
Schistosoma mansoni ap endonuclease 0.0096 0.0154 0.0154
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0053 0.0053
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-15, Bmcyp-15 0.0014 0.0009 0.0008
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-3, Bmcyp-3 0.0014 0.0009 0.0008
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0018 0.0015 0.0015
Brugia malayi acetyltransferase, GNAT family protein 0.0298 0.0514 0.0513
Schistosoma mansoni hypothetical protein 0.029 0.05 0.05
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0018 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0308 0.0532 0.0532
Echinococcus multilocularis pyruvate kinase 0.0066 0.0101 0.0101
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0101 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0282 0.0378
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0061 0.0091 0.011
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0084 0.0102
Mycobacterium ulcerans hypothetical protein 0.0168 0.0282 0.2874
Echinococcus granulosus peptidyl prolyl cis trans isomerase 3 0.0014 0.0009 0.0009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0083 0.0131 0.0131
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0038
Brugia malayi hypothetical protein 0.029 0.05 0.0499
Loa Loa (eye worm) hypothetical protein 0.0083 0.0131 0.0131
Echinococcus granulosus pyruvate kinase 0.0034 0.0044 0.0044
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0012 0.001
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.0018 0.0012
Plasmodium vivax unspecified product 0.0014 0.0009 0.0009
Brugia malayi Cathepsin L-like precursor 0.0011 0.0003 0.0002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0097 0.6283
Brugia malayi Pre-SET motif family protein 0.0212 0.036 0.0359
Schistosoma mansoni hypothetical protein 0.008 0.0126 0.0126
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0065 0.0099 0.0099
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0063 0.0072
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0126 0.0126
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.011 0.0136
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.008 0.0126 0.0126
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0054 0.0054
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.011 0.1289
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0076 0.0119 0.0159
Brugia malayi Cathepsin L-like precursor 0.0016 0.0012 0.0011
Brugia malayi MH2 domain containing protein 0.0358 0.0621 0.062
Loa Loa (eye worm) hypothetical protein 0.0046 0.0066 0.0066
Echinococcus granulosus intermediate filament protein 0.0135 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0374 0.0649 0.0648
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.001 0.0002
Onchocerca volvulus 0.0308 0.0532 0.053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0012 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0318 0.055 0.0726
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0439 0.0587
Loa Loa (eye worm) hypothetical protein 0.0152 0.0254 0.0254
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.011 0.1289
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0023 0.1486
Loa Loa (eye worm) steroid hormone receptor 0.0083 0.0131 0.0131
Entamoeba histolytica Ran family GTPase 0.0022 0.0023 0.0031
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0083 0.0131 0.0131
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0018 0.0015 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0439 0.0587
Leishmania major hypothetical protein, conserved 0.0025 0.0027 0.0025
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0053 0.0052
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase-like 0.0014 0.0009 0.0009
Echinococcus granulosus traf and tnf receptor associated protein 0.0019 0.0018 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0685 0.1203 0.1203
Schistosoma mansoni glutaminase 0.0548 0.0959 0.0959
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase-like 1 ppil1 0.0014 0.0009 0.0009
Mycobacterium ulcerans beta-lactamase 0.0071 0.011 0.1064
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0064 0.0064
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0019 0.0018 0.0012
Plasmodium vivax cyclophilin, putative 0.0014 0.0009 0.0009
Brugia malayi Importin beta-1 subunit 0.003 0.0037 0.0036
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0064 0.0074
Loa Loa (eye worm) cyclophilin 0.0014 0.0009 0.0009
Onchocerca volvulus Bile acid receptor homolog 0.0083 0.0131 0.0128
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0002
Schistosoma mansoni GTP-binding protein alpha subunit 0.0018 0.0015 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0083 0.0131 0.0131
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0083 0.0131 0.0131
Entamoeba histolytica hypothetical protein 0.0025 0.0027 0.0036
Brugia malayi beta-lactamase 0.0071 0.011 0.0109
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0061 0.0091 0.011
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0053 0.0053
Entamoeba histolytica peptidyl prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0012
Echinococcus granulosus peptidyl prolyl cis trans isomerase B 0.0014 0.0009 0.0009
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0053 0.0052
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.004 0.0054 0.0054
Schistosoma mansoni smad 0.0024 0.0026 0.0026
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0037 0.0038
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.001 0.0021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0015
Echinococcus multilocularis mothers against decapentaplegic 6 0.0011 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0012 0.0016
Echinococcus multilocularis U snRNP-associated cyclophilin protein 0.0014 0.0009 0.0009
Giardia lamblia Peptidyl-prolyl cis-trans isomerase B precursor 0.0014 0.0009 0.0012
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0015 0.002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0083 0.0131 0.013
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0119 0.0147
Echinococcus multilocularis neutral sphingomyelinase 0.0019 0.0018 0.0018
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0019 0.0018 0.0024
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.4201 0.7467 1
Loa Loa (eye worm) G protein alpha subunit 3 0.0018 0.0015 0.0015
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0096 0.0154 0.0206
Loa Loa (eye worm) peptidyl-prolyl cis-trans isomerase 11 0.0014 0.0009 0.0009
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0012
Echinococcus granulosus U snRNP-associated cyclophilin protein 0.0014 0.0009 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0207 0.0351 0.0351
Echinococcus granulosus peptidyl prolyl cis trans isomerase 2 0.0014 0.0009 0.0009
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0019 0.0018 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0064 0.0085
Brugia malayi hypothetical protein 0.0018 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0088 0.014 0.014
Schistosoma mansoni polycystin 1-related 0.5622 1 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0068 0.0104 0.1218
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.001 0.001
Plasmodium vivax importin-beta 2, putative 0.003 0.0037 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0131 0.0131
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0026 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0083 0.0131 0.013
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, cyclophilin-type domain-containing protein 0.0014 0.0009 0.0568
Brugia malayi photoreceptor-specific nuclear receptor 0.0083 0.0131 0.013
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.001 0.0002
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.4201 0.7467 0.7467
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0044 0.0044
Echinococcus granulosus lamin 0.0135 0.0223 0.0223
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0096 0.0154 0.0195
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0053 0.005
Loa Loa (eye worm) hypothetical protein 0.0065 0.0099 0.0099
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0131 0.013
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.001 0.0002
Trichomonas vaginalis peptidyl-prolyl cis-trans isomerase B precursor, putative 0.0014 0.0009 0.0012
Trichomonas vaginalis esterase, putative 0.0071 0.011 0.0147
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0015 0.002
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.4201 0.7467 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.011 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0031 0.0042
Leishmania major cathepsin L-like protease 0.0016 0.0012 0.0005
Brugia malayi pyruvate kinase, muscle isozyme 0.0014 0.0008 0.0007
Schistosoma mansoni inositol monophosphatase 0.0076 0.0119 0.0119
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0174 0.0292 0.0292
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0054 0.0072
Loa Loa (eye worm) nuclear factor I 0.0013 0.0007 0.0007
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0018 0.0015 0.0015
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0094 0.0114
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, cyclophilin-type domain-containing protein 0.0014 0.0009 0.0568
Trichomonas vaginalis peptidyl-prolyl cis-trans isomerase D, ppid, putative 0.0014 0.0009 0.0012
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0027 0.1785
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0018 0.0017
Giardia lamblia Histone acetyltransferase GCN5 0.008 0.0126 0.0169
Loa Loa (eye worm) cyclophilin-type peptidyl-prolyl cis-trans isomerase-15 0.0014 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.0439 0.0587
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0066 0.0101 0.1181
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0298 0.0514 0.0514
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0058
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0204 0.0204
Toxoplasma gondii cathepsin CPL 0.0016 0.0012 0.079
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0254 0.0435 0.0434
Schistosoma mansoni synaptojanin 0.0019 0.0018 0.0018
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0101 0.0099
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.0282 0.028
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0083 0.0131 0.013
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0019 0.0018 0.0018
Echinococcus multilocularis cysteine protease 0.0016 0.0012 0.0012
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0017 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0126 0.0125
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0012 0.0016
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0088 0.0139 0.9035
Echinococcus granulosus pyruvate kinase 0.0066 0.0101 0.0101
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0018 0.0015 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0018 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0036
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0003 0.0003
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0027 0.0025
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0018 0.0017
Schistosoma mansoni nocturnin 0.0019 0.0018 0.0018
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0018 0.0015 0.0015
Trypanosoma cruzi mitochondrial protein 99, putative 0.0019 0.0018 0.0012
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0012 0.001
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0012 0.0012
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0019 0.0018 0.0018
Echinococcus granulosus neutral sphingomyelinase 0.0019 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0012 0.0016
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.001 0.0014
Giardia lamblia hypothetical protein 0.0019 0.0018 0.0024
Brugia malayi TAR-binding protein 0.0127 0.0209 0.0208
Schistosoma mansoni eyes absent homolog 0.0088 0.014 0.014
Echinococcus granulosus mitogen activated protein kinase 0.0061 0.0091 0.0091
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.007 0.0083
Toxoplasma gondii cyclophilin, putative 0.0014 0.0009 0.0568
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0018 0.0015 0.002
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0019 0.0018 0.0012
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4192 0.7452 0.7452
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0094 0.0114
Echinococcus granulosus tar DNA binding protein 0.0127 0.0209 0.0209
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0131 0.013
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0209 0.0209
Brugia malayi Cytochrome P450 family protein 0.0045 0.0063 0.0062
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.1139
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0009
Echinococcus multilocularis lamin 0.0135 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.008 0.0126 0.0126
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0096 0.0154 0.0195
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.009 0.0109
Onchocerca volvulus 0.0071 0.011 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0058
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0054 0.0054
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.009 0.009
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0083 0.0131 0.0131
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.011 0.011
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0012 0.0012
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.001 0.001
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) TAR-binding protein 0.0127 0.0209 0.0209
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.009 0.0857
Plasmodium falciparum LCCL domain-containing protein 0.5622 1 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0083 0.0131 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0047 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0009 0.0012
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0018 0.0015 0.0015
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0101 0.0099
Echinococcus granulosus histone acetyltransferase KAT2B 0.0088 0.0139 0.0139
Echinococcus granulosus geminin 0.0685 0.1203 0.1203
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0065 0.0099 0.0099
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0061 0.0091 0.0091
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0002 0.0002
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.0024
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0012
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-6, Bmcyp-6 0.0014 0.0009 0.0008
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0083 0.0131 0.0131
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0012 0.0012
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0053 0.0052
Brugia malayi CXXC zinc finger family protein 0.0029 0.0035 0.0034
Schistosoma mansoni GTP-binding protein alpha subunit 0.0018 0.0015 0.0015
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.001 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0298 0.0399
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.001 0.001
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.011 0.0147
Schistosoma mansoni hypothetical protein 0.008 0.0126 0.0126
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0061 0.006
Brugia malayi RNA, U transporter 1 0.0086 0.0137 0.0136
Echinococcus multilocularis pyruvate kinase 0.0034 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0003
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.001 0.0673
Plasmodium vivax vivapain-2 0.0016 0.0012 0.0012
Onchocerca volvulus Huntingtin homolog 0.0374 0.0649 0.0646
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0018 0.0015 0.0014
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0012 0.001
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0018 0.0015 0.002
Schistosoma mansoni ran 0.0022 0.0023 0.0023
Mycobacterium leprae Probable pyruvate kinase PykA 0.0066 0.0101 0.9166
Plasmodium vivax cyclophilin, putative 0.0014 0.0009 0.0009
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0019 0.0018 0.0024
Echinococcus multilocularis peptidyl prolyl isomerase G 0.0014 0.0009 0.0009
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0012 0.0012
Onchocerca volvulus 0.0014 0.0009 0.0006
Brugia malayi Pyruvate kinase, muscle isozyme 0.0066 0.0101 0.01
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0119 0.0159
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0054 0.006
Onchocerca volvulus 0.0018 0.0015 0.0013
Brugia malayi isocitrate dehydrogenase 0.0015 0.001 0.0009
Schistosoma mansoni hypothetical protein 0.0124 0.0204 0.0204
Entamoeba histolytica G protein alpha subunit, putative 0.0018 0.0015 0.002
Schistosoma mansoni retinoic acid receptor RXR 0.0083 0.0131 0.0131
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0151 0.0252 0.0326
Mycobacterium ulcerans pyruvate kinase 0.0066 0.0101 0.0975
Onchocerca volvulus 0.0071 0.011 0.0107
Brugia malayi Calcitonin receptor-like protein seb-1 0.0254 0.0435 0.0434
Loa Loa (eye worm) hypothetical protein 0.0071 0.011 0.011
Onchocerca volvulus 0.0241 0.0412 0.041
Mycobacterium ulcerans lipase LipD 0.0071 0.011 0.1064
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.4201 0.7467 1
Loa Loa (eye worm) DEAH box polypeptide 35 0.0039 0.0052 0.0052
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-4, Bmcyp-4 0.0014 0.0009 0.0008
Treponema pallidum hypothetical protein 0.0019 0.0018 0.0606
Echinococcus multilocularis protein S isoprenylcysteine O methyltransferase 0.0014 0.0009 0.0009
Echinococcus granulosus pyruvate kinase 0.0066 0.0101 0.0101
Brugia malayi nuclear receptor RXR 0.0044 0.0061 0.006
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0047 0.0052
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0199 0.0338 0.0337
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.001 0.001
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0018 0.0015 0.0015
Loa Loa (eye worm) cyclophilin-type peptidyl-prolyl cis-trans isomerase-16 0.0014 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0027 0.0025
Schistosoma mansoni Smad4 0.0011 0.0002 0.0002
Schistosoma mansoni nuclear receptor 0.0039 0.0053 0.0053
Mycobacterium ulcerans hypothetical protein 0.0071 0.011 0.1064
Brugia malayi pyruvate kinase 0.0014 0.0008 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.011 0.0147
Echinococcus multilocularis geminin 0.0685 0.1203 0.1203
Brugia malayi cyclophilin-type peptidyl-prolyl cis-trans isomerase-2, Bmcyp-2 0.0014 0.0009 0.0008
Entamoeba histolytica acetyltransferase, GNAT family 0.008 0.0126 0.0169
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.002 0.0018 0.0024
Onchocerca volvulus 0.0199 0.0338 0.0336
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0018 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0083 0.0131 0.0131
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.1139
Entamoeba histolytica DNA repair and recombination protein, putative 0.4201 0.7467 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.5622 1 1
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.011 0.1289
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.0131 0.013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0038 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0058
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0126 0.0126
Brugia malayi cytoplasmic intermediate filament protein 0.0072 0.0112 0.0111
Loa Loa (eye worm) histone methyltransferase 0.001 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0062 0.0094 0.0114
Echinococcus multilocularis smad 0.0024 0.0026 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0282 0.0378
Schistosoma mansoni cript-related 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0002
Brugia malayi hypothetical protein 0.0016 0.0012 0.0011
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.001 0.0002
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0083 0.0131 0.0131
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0114
Brugia malayi hypothetical protein 0.0039 0.0053 0.0052
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0018 0.0015 0.0015
Echinococcus granulosus histone acetyltransferase KAT2B 0.029 0.0499 0.0499
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0019 0.0018 0.0018
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0021 0.0017
Brugia malayi Probable ATP-dependent helicase DHX35 0.0039 0.0052 0.0051
Echinococcus multilocularis neuropeptide s receptor 0.0474 0.0828 0.0828
Entamoeba histolytica hypothetical protein, conserved 0.4201 0.7467 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0061 0.0061
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.011 0.0147
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0027 0.0027
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0064 0.0063
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.009 0.009
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.009 0.5853
Echinococcus multilocularis peptidyl prolyl cis trans isomerase CWC27 0.0014 0.0009 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.009 0.0857
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0054 0.0054
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0018 0.0015 0.0015
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase (cyclophilin) 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0152 0.0254 0.0254
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.4201 0.7467 0.7467
Echinococcus granulosus Smad4 0.0024 0.0026 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0058
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0053 0.0053
Brugia malayi Cathepsin L-like precursor 0.0016 0.0012 0.0011
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0019 0.0018 0.0024
Onchocerca volvulus 0.5622 1 1
Echinococcus granulosus RUN 0.5622 1 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0012 0.0016
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0027 0.0036
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0101 0.0136
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.011 0.011
Schistosoma mansoni cyclophilin B 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0052 0.0052
Schistosoma mansoni pyruvate kinase 0.0034 0.0044 0.0044
Echinococcus multilocularis musashi 0.0135 0.0223 0.0223
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0083 0.0131 0.0131
Brugia malayi nuclear hormone receptor 0.0039 0.0053 0.0052
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0061 0.0061
Loa Loa (eye worm) intermediate filament protein 0.0135 0.0223 0.0223
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.029 0.05 0.05
Onchocerca volvulus 0.0016 0.0012 0.001
Echinococcus multilocularis pyruvate kinase 0.0052 0.0076 0.0076
Brugia malayi peptidyl-prolyl cis-trans isomerase, cyclophilin-type family protein 0.0014 0.0009 0.0008
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0096 0.0154 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.001 0.0014
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.011 0.011
Brugia malayi nuclear receptor NHR-67 0.0039 0.0053 0.0052
Leishmania major cathepsin L-like protease 0.0062 0.0094 0.0114
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0282 0.0378
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0038 0.0038
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0091 0.011
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0018 0.0015 0.002
Brugia malayi Intermediate filament tail domain containing protein 0.0135 0.0223 0.0222
Trypanosoma brucei RNA editing exonuclease 2 0.0019 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0254 0.0435 0.0435
Brugia malayi nuclear receptor RXR 0.0039 0.0053 0.0052
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0012 0.0016
Trichomonas vaginalis peptidyl-prolyl cis-trans isomerase, putative 0.0014 0.0009 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0047 0.0063
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0019 0.0018 0.0012
Echinococcus granulosus cpg binding protein 0.0031 0.0038 0.0038
Brugia malayi Cathepsin L-like precursor 0.0011 0.0003 0.0002
Schistosoma mansoni loxhd1 0.5622 1 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0101 0.0124
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.001 0.0002
Leishmania major pyruvate kinase 0.0066 0.0101 0.0124
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0083 0.0131 0.0131
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.4201 0.7467 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0047 0.0063
Loa Loa (eye worm) Smad1 0.0024 0.0026 0.0026
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0018 0.1139
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0038 0.0038
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0054 0.006
Brugia malayi MH2 domain containing protein 0.0024 0.0026 0.0026
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.001 0.001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.011 0.1064
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0012 0.0016
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0012 0.0011
Brugia malayi beta-lactamase family protein 0.0071 0.011 0.0109
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0063 0.0072
Schistosoma mansoni intermediate filament proteins 0.0135 0.0223 0.0223
Echinococcus multilocularis peptidyl prolyl cis trans isomerase 4 0.0014 0.0009 0.0009
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.0018 0.0012
Schistosoma mansoni cpg binding protein 0.0031 0.0038 0.0038
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0019 0.0018 0.0018
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0019 0.0018 0.0012
Schistosoma mansoni peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0132 0.0219 0.0219
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0019 0.0018 0.0018
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0027 0.0027
Schistosoma mansoni pyruvate kinase 0.0066 0.0101 0.0101
Leishmania major cathepsin L-like protease 0.0016 0.0012 0.0005
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0018 0.0015 0.0015
Schistosoma mansoni pyruvate kinase 0.0066 0.0101 0.0101
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0209 0.0209
Echinococcus multilocularis cpg binding protein 0.0031 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0083 0.0131 0.0131
Echinococcus multilocularis RUN 0.5622 1 1
Loa Loa (eye worm) pyruvate kinase 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Toxoplasma gondii non-specific serine/threonine protein kinase 0.001 0.0000051633 0.0003
Echinococcus granulosus expressed protein 0.0014 0.0009 0.0009
Brugia malayi follicle stimulating hormone receptor 0.0251 0.043 0.043
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0019 0.0018 0.0012
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0053 0.005
Schistosoma mansoni synaptojanin 0.0019 0.0018 0.0018
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0003 0.0003
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0019 0.0018 0.0024
Echinococcus multilocularis expressed protein 0.0018 0.0015 0.0015
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0064 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0131 0.013
Leishmania major hypothetical protein, conserved 0.0071 0.011 0.0136
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0209 0.0209
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0064 0.0085
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0018 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0035 0.0048
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0019 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0083 0.0131 0.013
Echinococcus granulosus snurportin 1 0.0325 0.0561 0.0561
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0031 0.0041
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0083 0.0131 0.0131
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0012 0.0016
Schistosoma mansoni cyclophilin 0.0014 0.0009 0.0009
Echinococcus multilocularis peptidyl prolyl cis trans isomerase 1 0.0014 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0282 0.0378
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.011 0.1289
Echinococcus multilocularis importin subunit beta 1 0.003 0.0037 0.0037
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase 0.0014 0.0009 0.0009
Onchocerca volvulus 0.0019 0.0018 0.0015
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0064 0.0085
Onchocerca volvulus 0.5622 1 1
Echinococcus granulosus dnaJ subfamily B 0.0417 0.0726 0.0726
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0019 0.0018 0.0012
Mycobacterium tuberculosis Conserved protein 0.0071 0.011 0.1289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0083 0.0131 0.0131
Brugia malayi Pyruvate kinase, M2 isozyme 0.0066 0.0101 0.01
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0018 0.0017
Echinococcus multilocularis pyruvate kinase 0.0034 0.0044 0.0044
Brugia malayi ecdysone receptor 0.0039 0.0053 0.0052
Treponema pallidum exodeoxyribonuclease (exoA) 0.0096 0.0154 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0298 0.0514 0.0514
Onchocerca volvulus 0.0039 0.0053 0.005
Echinococcus multilocularis mitogen activated protein kinase 3 0.0061 0.0091 0.0091
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0023 0.0023
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0054 0.0054
Brugia malayi MH2 domain containing protein 0.0011 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0064 0.0085
Loa Loa (eye worm) acetyltransferase 0.0298 0.0514 0.0514
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.0018
Brugia malayi Smad1 0.0024 0.0026 0.0026
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.011 0.1289
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0018 0.0015 0.0014

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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