Detailed information for compound 1634466

Basic information

Technical information
  • TDR Targets ID: 1634466
  • Name: N'-(6-chloro-2-methoxy-4,5-dimethylacridin-9- yl)-N,N-diethylpentane-1,4-diamine
  • MW: 428.01 | Formula: C25H34ClN3O
  • H donors: 1 H acceptors: 1 LogP: 6.76 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(CCCC(Nc1c2cc(OC)cc(c2nc2c1ccc(c2C)Cl)C)C)CC
  • InChi: 1S/C25H34ClN3O/c1-7-29(8-2)13-9-10-17(4)27-25-20-11-12-22(26)18(5)24(20)28-23-16(3)14-19(30-6)15-21(23)25/h11-12,14-15,17H,7-10,13H2,1-6H3,(H,27,28)
  • InChiKey: YVKWDYYNICMEEA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N'-(6-chloro-2-methoxy-4,5-dimethyl-acridin-9-yl)-N,N-diethyl-pentane-1,4-diamine
  • N'-(6-chloro-2-methoxy-4,5-dimethyl-9-acridinyl)-N,N-diethylpentane-1,4-diamine
  • (6-chloro-2-methoxy-4,5-dimethyl-acridin-9-yl)-(4-diethylamino-1-methyl-butyl)amine
  • NCI60_007996
  • AIDS156575
  • NSC625628 (HYDROCHLORIDE SALT)
  • N~4~-(6-Chloro-2-methoxy-4,5-dimethyl-9-acridinyl)-N~1~,N~1~-diethyl-1,4-pentanediamine hydrochloride
  • AIDS-156575

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.008 0.0191
Echinococcus granulosus thyroid hormone receptor alpha 0.0367 0.1931 0.46
Brugia malayi Nuclear hormone receptor-like 1 0.0412 0.2174 0.5178
Schistosoma mansoni polycystin 1-related 0.0543 0.2897 0.2897
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0116 0.0871
Loa Loa (eye worm) hypothetical protein 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0779 0.4199 1
Schistosoma mansoni retinoic acid receptor RXR 0.0779 0.4199 0.4199
Toxoplasma gondii ABC1 family protein 0.0038 0.0116 1
Brugia malayi orphan nuclear receptor NR2E1 0.0367 0.1931 0.46
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0116 0.0871
Loa Loa (eye worm) steroid hormone receptor 0.0779 0.4199 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0543 0.2897 0.6899
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0779 0.4199 0.4199
Mycobacterium leprae Probable lipase LipE 0.0038 0.0116 0.5
Loa Loa (eye worm) hypothetical protein 0.0543 0.2897 0.6899
Brugia malayi beta-lactamase 0.0038 0.0116 0.0276
Brugia malayi ecdysone receptor 0.0367 0.1931 0.46
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0779 0.4199 1
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0116 1
Mycobacterium ulcerans beta-lactamase 0.0038 0.0116 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0779 0.4199 1
Schistosoma mansoni nuclear receptor 0.0367 0.1931 0.1931
Brugia malayi Nuclear hormone receptor-like 1 0.0779 0.4199 1
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0116 1
Onchocerca volvulus 0.025 0.1284 0.2923
Brugia malayi hypothetical protein 0.0412 0.2174 0.5178
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0367 0.1931 0.4494
Brugia malayi hypothetical protein 0.0543 0.2897 0.6899
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0779 0.4199 1
Brugia malayi hypothetical protein 0.0367 0.1931 0.46
Schistosoma mansoni nuclear receptor 0.0367 0.1931 0.1931
Mycobacterium tuberculosis Conserved protein 0.0038 0.0116 0.0871
Leishmania major hypothetical protein, conserved 0.0038 0.0116 1
Schistosoma mansoni lipoxygenase 0.0543 0.2897 0.2897
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0116 0.0844
Schistosoma mansoni thyroid hormone receptor 0.0779 0.4199 0.4199
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0779 0.4199 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0779 0.4199 0.4199
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0779 0.4199 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0367 0.1931 0.46
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0116 1
Brugia malayi beta-lactamase family protein 0.0038 0.0116 0.0276
Loa Loa (eye worm) hypothetical protein 0.0412 0.2174 0.5178
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.008 0.6678
Loa Loa (eye worm) beta-lactamase 0.0038 0.0116 0.0276
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0367 0.1931 0.4494
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0367 0.1931 0.1931
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0367 0.1931 0.46
Echinococcus multilocularis thyroid hormone receptor alpha 0.0779 0.4199 1
Brugia malayi nuclear hormone receptor 0.0779 0.4199 1
Schistosoma mansoni hypothetical protein 0.0543 0.2897 0.2897
Brugia malayi Doublecortin family protein 0.0543 0.2897 0.6899
Brugia malayi beta-lactamase family protein 0.0038 0.0116 0.0276
Echinococcus granulosus nuclear receptor nhr 48 0.0367 0.1931 0.46
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0779 0.4199 1
Schistosoma mansoni hypothetical protein 0.0166 0.0823 0.0823
Brugia malayi MH2 domain containing protein 0.0249 0.1278 0.3045
Mycobacterium ulcerans hypothetical protein 0.0038 0.0116 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0779 0.4199 1
Brugia malayi Nuclear hormone receptor E75 0.0367 0.1931 0.46
Schistosoma mansoni hypothetical protein 0.0166 0.0823 0.0823
Onchocerca volvulus 0.0779 0.4199 1
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.1278 0.3045
Schistosoma mansoni ap endonuclease 0.0018 0.0008 0.0008
Echinococcus multilocularis ecdysone induced protein 78C 0.0779 0.4199 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0779 0.4199 0.4199
Brugia malayi Pre-SET motif family protein 0.022 0.1117 0.266
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0412 0.2174 0.5178
Echinococcus multilocularis lipoxygenase domain containing protein 0.0543 0.2897 0.6899
Brugia malayi photoreceptor-specific nuclear receptor 0.0779 0.4199 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0412 0.2174 0.2174
Mycobacterium tuberculosis Conserved protein 0.0038 0.0116 0.0871
Brugia malayi Pre-SET motif family protein 0.0032 0.008 0.0191
Onchocerca volvulus 0.0038 0.0116 0.0087
Loa Loa (eye worm) hypothetical protein 0.0779 0.4199 1
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0116 0.5
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0779 0.4199 1
Plasmodium falciparum LCCL domain-containing protein 0.0543 0.2897 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0779 0.4199 1
Echinococcus multilocularis geminin 0.0166 0.0823 0.1959
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0116 0.0871
Loa Loa (eye worm) nuclear receptor NHR-67 0.0367 0.1931 0.46
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.1278 0.3045
Schistosoma mansoni nuclear hormone receptor 0.0367 0.1931 0.1931
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0412 0.2174 0.5178
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.008 0.008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0116 0.0116
Onchocerca volvulus Protein ultraspiracle homolog 0.0779 0.4199 1
Brugia malayi Steroid receptor seven-up type 2 0.0779 0.4199 1
Onchocerca volvulus 0.0543 0.2897 0.6839
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0008 0.5
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0367 0.1931 0.46
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0116 0.0276
Loa Loa (eye worm) hypothetical protein 0.0779 0.4199 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.008 0.0191
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0412 0.2174 0.2174
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0367 0.1931 0.46
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0779 0.4199 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0116 0.0871
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0008 0.5
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0116 0.0373
Echinococcus granulosus Nuclear hormone receptor HR96 0.0367 0.1931 0.46
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0367 0.1931 0.46
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0008 0.002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0412 0.2174 0.5178
Loa Loa (eye worm) hypothetical protein 0.0038 0.0116 0.0276
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.008 0.008
Onchocerca volvulus 0.0367 0.1931 0.4494
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0367 0.1931 0.46
Plasmodium vivax SET domain protein, putative 0.0032 0.008 0.0249
Loa Loa (eye worm) hypothetical protein 0.0779 0.4199 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0779 0.4199 0.4199
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0008 0.002
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0008 0.5
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0116 1
Brugia malayi steroid hormone receptor 0.0779 0.4199 1
Loa Loa (eye worm) nuclear hormone receptor 0.0367 0.1931 0.46
Onchocerca volvulus 0.0367 0.1931 0.4494
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0779 0.4199 1
Schistosoma mansoni thyroid hormone receptor 0.0779 0.4199 0.4199
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0116 0.0276
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0779 0.4199 1
Brugia malayi hypothetical protein 0.0543 0.2897 0.6899
Brugia malayi Nuclear hormone receptor E75 0.0367 0.1931 0.46
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0367 0.1931 0.46
Brugia malayi nuclear receptor NHR-88 0.0779 0.4199 1
Schistosoma mansoni nuclear hormone receptor 0.0779 0.4199 0.4199
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0116 0.0844
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0116 0.0844
Loa Loa (eye worm) hypothetical protein 0.0412 0.2174 0.5178
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0779 0.4199 1
Onchocerca volvulus 0.0038 0.0116 0.0087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0367 0.1931 0.46
Onchocerca volvulus Bile acid receptor homolog 0.0779 0.4199 1
Brugia malayi tailless protein 0.0367 0.1931 0.46
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0779 0.4199 1
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0116 0.0871
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0008 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0116 0.0844
Schistosoma mansoni nuclear receptor nhr-48 0.0367 0.1931 0.1931
Schistosoma mansoni rab6-interacting 0.0543 0.2897 0.2897
Schistosoma mansoni rab6-interacting 0.0543 0.2897 0.2897
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0074 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0779 0.4199 1
Trichomonas vaginalis set domain proteins, putative 0.025 0.1284 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0116 0.0276
Echinococcus granulosus ecdysone induced protein 78C 0.0779 0.4199 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.008 0.0191
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0779 0.4199 0.4199
Brugia malayi nuclear hormone receptor family member nhr-6 0.0367 0.1931 0.46
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0116 0.0276
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0367 0.1931 0.46
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0116 0.0276
Brugia malayi nuclear receptor RXR 0.0367 0.1931 0.46
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0116 0.0276
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.008 0.008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0779 0.4199 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0116 1
Schistosoma mansoni RAR-like nuclear receptor 0.0779 0.4199 0.4199
Loa Loa (eye worm) DR-78 0.0367 0.1931 0.46
Brugia malayi nuclear hormone receptor 0.0367 0.1931 0.46
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0779 0.4199 0.4199
Echinococcus granulosus Polycystic kidney disease protein 0.0543 0.2897 0.6899
Echinococcus multilocularis nuclear receptor nhr 48 0.0367 0.1931 0.46
Loa Loa (eye worm) hypothetical protein 0.0412 0.2174 0.5178
Schistosoma mansoni ap endonuclease 0.0018 0.0008 0.0008
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0116 0.0871
Loa Loa (eye worm) doublecortin family protein 0.0543 0.2897 0.6899
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0779 0.4199 1
Schistosoma mansoni coup transcription factor 0.0779 0.4199 0.4199
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0779 0.4199 1
Brugia malayi ecdysteroid receptor 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0116 0.0276
Brugia malayi hypothetical protein 0.0412 0.2174 0.5178
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0008 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0779 0.4199 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.008 0.008
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0779 0.4199 1
Brugia malayi Nuclear hormone receptor-like 1 0.0412 0.2174 0.5178
Echinococcus multilocularis RUN 0.0543 0.2897 0.6899
Echinococcus granulosus lipoxygenase domain containing protein 0.0543 0.2897 0.6899
Trichomonas vaginalis esterase, putative 0.0038 0.0116 0.0844
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0779 0.4199 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0116 0.0276
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0779 0.4199 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0779 0.4199 0.4199
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0779 0.4199 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.008 0.0191
Plasmodium vivax multidomain scavenger receptor, putative 0.0543 0.2897 1
Mycobacterium ulcerans lipase LipD 0.0038 0.0116 1
Echinococcus multilocularis FTZ F1 alpha 0.0779 0.4199 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0543 0.2897 0.6899
Loa Loa (eye worm) hypothetical protein 0.0779 0.4199 1
Brugia malayi nuclear receptor NHR-88 0.0367 0.1931 0.46
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Loa Loa (eye worm) hypothetical protein 0.0779 0.4199 1
Schistosoma mansoni nuclear hormone receptor 0.0367 0.1931 0.1931
Mycobacterium tuberculosis Conserved protein 0.0038 0.0116 0.0871
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0116 0.0871
Brugia malayi conserved hypotetical protein 0.0367 0.1931 0.46
Schistosoma mansoni zinc finger protein 0.0367 0.1931 0.1931
Onchocerca volvulus 0.0543 0.2897 0.6839
Loa Loa (eye worm) hypothetical protein 0.0412 0.2174 0.5178
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0116 0.0844
Echinococcus granulosus geminin 0.0166 0.0823 0.1959
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0116 0.0116
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0412 0.2174 0.5178
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0779 0.4199 1
Echinococcus granulosus RUN 0.0543 0.2897 0.6899
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.1244 1
Brugia malayi hypothetical protein 0.0367 0.1931 0.46
Loa Loa (eye worm) hypothetical protein 0.0367 0.1931 0.46
Loa Loa (eye worm) hypothetical protein 0.0543 0.2897 0.6899
Echinococcus granulosus FTZ F1 alpha 0.0779 0.4199 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0116 0.0276
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0367 0.1931 0.46
Brugia malayi nuclear receptor NHR-67 0.0367 0.1931 0.46
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0779 0.4199 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0008 0.5
Schistosoma mansoni loxhd1 0.0543 0.2897 0.2897
Onchocerca volvulus 0.0038 0.0116 0.0087
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0779 0.4199 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0779 0.4199 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.022 0.1117 0.266
Brugia malayi nuclear hormone receptor family member odr-7 0.0367 0.1931 0.46
Brugia malayi nuclear receptor RXR 0.0412 0.2174 0.5178
Echinococcus granulosus lipoxygenase domain containing protein 0.0543 0.2897 0.6899

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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