Detailed information for compound 163643

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 199.209 | Formula: C11H9N3O
  • H donors: 1 H acceptors: 3 LogP: 2.02 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cn1c(O)nc2c1cc1ccccc1n2
  • InChi: 1S/C11H9N3O/c1-14-9-6-7-4-2-3-5-8(7)12-10(9)13-11(14)15/h2-6H,1H3,(H,12,13,15)
  • InChiKey: PAFMJYHJVIDVQK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Loa Loa (eye worm) NHE-3 0.0031 0.0467 0.0493
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0695 0.0894
Echinococcus granulosus sodium:hydrogen exchanger 0.0031 0.0467 0.0601
Schistosoma mansoni tyrosine kinase 0.0085 0.1809 0.2328
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0279 0.0295
Brugia malayi GH02984p 0.0083 0.1763 0.1861
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0172 0.0172
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0172 0.0221
Echinococcus granulosus p2X purinoceptor 4 0.0276 0.6564 0.8446
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0036 0.0591 0.076
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0393 0.9477 1
Brugia malayi nuclear receptor NHR-88 0.0019 0.0172 0.0181
Giardia lamblia Sodium/hydrogen exchanger 3 0.0031 0.0467 1
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0016 0.0092 1
Echinococcus multilocularis p2X purinoceptor 4 0.0276 0.6564 0.8446
Schistosoma mansoni tyrosine kinase 0.0083 0.1761 0.2265
Schistosoma mansoni thyroid hormone receptor 0.004 0.0695 0.0894
Schistosoma mansoni thyroid hormone receptor 0.004 0.0695 0.0894
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0016 0.0092 0.3447
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0172 0.0221
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0036 0.0591 0.076
Echinococcus granulosus sodium:hydrogen exchanger 0.0031 0.0467 0.0601
Schistosoma mansoni sodium/hydrogen exchanger 2 (nhe2) 0.0031 0.0467 0.0601
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0695 0.0894
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0695 0.0733
Schistosoma mansoni high-affinity choline transporter 0.0083 0.1763 0.2269
Brugia malayi hypothetical protein 0.0021 0.0228 0.024
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0695 0.0733
Schistosoma mansoni zinc finger protein 0.0019 0.0172 0.0221
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0695 0.0894
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0695 0.0695
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0013 0.0037 0.0047
Echinococcus granulosus sodium channel protein 0.0175 0.4049 0.5209
Onchocerca volvulus 0.0019 0.0172 0.0172
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0031 0.0467 0.0467
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0031 0.0467 0.0601
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0031 0.0467 0.0601
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0172 0.0181
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0695 0.0894
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0695 0.0733
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0695 0.0894
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0695 0.0733
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0016 0.0092 1
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0172 0.0221
Brugia malayi ecdysteroid receptor 0.004 0.0695 0.0733
Loa Loa (eye worm) hypothetical protein 0.0021 0.0228 0.024
Echinococcus granulosus sodium:hydrogen exchanger 2 (nhe2) 0.0025 0.0322 0.0414
Loa Loa (eye worm) hypothetical protein 0.0031 0.0467 0.0493
Loa Loa (eye worm) hypothetical protein 0.004 0.0695 0.0733
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0695 0.0894
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0695 0.0733
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0695 0.0733
Echinococcus multilocularis sodium channel protein 0.0175 0.4049 0.5209
Loa Loa (eye worm) hypothetical protein 0.0031 0.0467 0.0493
Echinococcus multilocularis sodium:hydrogen exchanger 0.0031 0.0467 0.0601
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0031 0.0467 0.0467
Plasmodium vivax DNA polymerase alpha, putative 0.0029 0.0423 1
Echinococcus granulosus sodium:glucose cotransporter 0.0324 0.7772 1
Schistosoma mansoni P2X receptor subunit 0.0276 0.6564 0.8446
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0083 0.1763 1
Onchocerca volvulus 0.0083 0.1763 0.1763
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0031 0.0467 0.0467
Brugia malayi hypothetical protein 0.0019 0.0172 0.0181
Brugia malayi Kringle domain containing protein 0.0023 0.0266 0.028
Echinococcus granulosus high affinity choline transporter 1 0.0083 0.1763 0.2269
Schistosoma mansoni inositol transporter 0.0324 0.7772 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0695 0.0894
Brugia malayi nuclear receptor RXR 0.0019 0.0172 0.0181
Entamoeba histolytica aldose reductase, putative 0.0012 0 0.5
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0695 0.0894
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0695 0.0733
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0695 0.0894
Loa Loa (eye worm) hypothetical protein 0.004 0.0695 0.0733
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0695 0.0894
Onchocerca volvulus 0.0019 0.0172 0.0172
Brugia malayi Protein kinase domain containing protein 0.0023 0.0279 0.0295
Brugia malayi nuclear receptor RXR 0.0021 0.0228 0.024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0695 0.0733
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0031 0.0467 0.0601
Loa Loa (eye worm) hypothetical protein 0.0374 0.901 0.9507
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0228 0.0293
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0172 0.0181
Brugia malayi Sodium:solute symporter family protein 0.0083 0.1763 0.1861
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0172 0.0221
Loa Loa (eye worm) hypothetical protein 0.0021 0.0228 0.024
Echinococcus granulosus p2X purinoceptor 4 0.0276 0.6564 0.8446
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0172 0.0221
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0228 0.024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0266 0.028
Schistosoma mansoni P2X receptor subunit 0.0276 0.6564 0.8446
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0172 0.0221
Loa Loa (eye worm) hypothetical protein 0.004 0.0695 0.0733
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0695 0.0733
Echinococcus granulosus solute carrier family 5 0.0324 0.7772 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0172 0.0181
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0172 0.0221
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.0031 0.0467 0.0493
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0172 0.0181
Schistosoma mansoni coup transcription factor 0.004 0.0695 0.0894
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0172 0.0181
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0695 0.0733
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0266 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0172 0.0221
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0252 0.5975 0.7688
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0231 0.5452 0.7015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0172 0.0221
Entamoeba histolytica aldose reductase, putative 0.0012 0 0.5
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0228 0.0293
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0695 0.0894
Brugia malayi ecdysone receptor 0.0019 0.0172 0.0181
Loa Loa (eye worm) hypothetical protein 0.004 0.0695 0.0733
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0175 0.4049 1
Echinococcus multilocularis solute carrier family 5 0.0324 0.7772 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0228 0.0293
Toxoplasma gondii kringle domain-containing protein 0.0023 0.0266 0.1507
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0172 0.0221
Schistosoma mansoni nuclear receptor 0.0019 0.0172 0.0221
Echinococcus granulosus tyrosine protein kinase shark 0.0085 0.1809 0.2328
Brugia malayi steroid hormone receptor 0.004 0.0695 0.0733
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0695 0.0733
Schistosoma mansoni nuclear hormone receptor 0.004 0.0695 0.0894
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0228 0.0293
Loa Loa (eye worm) hypothetical protein 0.0021 0.0228 0.024
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0695 0.0894
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0695 0.0733
Brugia malayi nuclear hormone receptor 0.004 0.0695 0.0733
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0228 0.024
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0172 0.0221
Loa Loa (eye worm) sodium/hydrogen exchanger 3 family protein 0.0031 0.0467 0.0493
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0695 0.0894
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0029 0.0423 0.24
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0031 0.0467 0.0601
Loa Loa (eye worm) hypothetical protein 0.004 0.0695 0.0733
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0695 0.0733
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Echinococcus multilocularis tissue type plasminogen activator 0.0023 0.0266 0.0342
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0695 0.0733
Brugia malayi nuclear receptor NHR-88 0.004 0.0695 0.0733
Brugia malayi tailless protein 0.0019 0.0172 0.0181
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0695 0.0894
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0695 0.0894
Loa Loa (eye worm) hypothetical protein 0.0021 0.0228 0.024
Loa Loa (eye worm) hypothetical protein 0.0031 0.0467 0.0493
Schistosoma mansoni sodium/hydrogen exchanger 0.0031 0.0467 0.0601
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0083 0.1763 0.2269
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0695 0.0894
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0695 0.0733
Schistosoma mansoni sodium/solute symporter 0.0083 0.1763 0.2269
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0324 0.7772 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.1763 0.1861
Schistosoma mansoni inositol transporter 0.0324 0.7772 1
Mycobacterium ulcerans oxidoreductase 0.0012 0 0.5
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0695 0.0733
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0695 0.0733
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0695 0.0733
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0695 0.0894
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0172 0.0221
Loa Loa (eye worm) hypothetical protein 0.0083 0.1763 0.1861
Loa Loa (eye worm) hypothetical protein 0.004 0.0695 0.0733
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0695 0.0695
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0016 0.0092 0.0226
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0083 0.1763 0.2269
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0695 0.0894
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0172 0.0172
Brugia malayi DNA polymerase alpha catalytic subunit 0.0029 0.0423 0.0447
Schistosoma mansoni nuclear receptor 0.0019 0.0172 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0695 0.0733
Echinococcus granulosus sodium:glucose cotransporter 2 0.0324 0.7772 1
Leishmania major hypothetical protein, conserved 0.0023 0.0266 0.0656
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0031 0.0467 0.0601
Onchocerca volvulus 0.0023 0.0266 0.0266
Echinococcus multilocularis tyrosine protein kinase shark 0.0085 0.1809 0.2328
Brugia malayi nuclear receptor NHR-67 0.0019 0.0172 0.0181
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0695 0.0894
Plasmodium falciparum cysteine repeat modular protein 1 0.0023 0.0266 0.5
Loa Loa (eye worm) hypothetical protein 0.004 0.0695 0.0733
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Loa Loa (eye worm) hypothetical protein 0.0049 0.0922 0.0973
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0036 0.0591 0.076
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0172 0.0181
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0228 0.024
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0175 0.4049 0.5209
Trichomonas vaginalis DNA polymerase II, putative 0.0016 0.0092 1
Schistosoma mansoni retinoic acid receptor RXR 0.0252 0.5975 0.7688
Echinococcus multilocularis high affinity choline transporter 1 0.0083 0.1763 0.2269
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0695 0.0733
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0695 0.0894
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0172 0.0221
Loa Loa (eye worm) DR-78 0.0019 0.0172 0.0181
Echinococcus granulosus FTZ F1 alpha 0.004 0.0695 0.0894
Echinococcus granulosus sodium:myo inositol cotransporter 0.0324 0.7772 1
Echinococcus granulosus p2X purinoceptor 4 0.0276 0.6564 0.8446
Loa Loa (eye worm) sodium/hydrogen exchanger 0.0031 0.0467 0.0493
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0695 0.0733
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0695 0.0894
Echinococcus multilocularis p2X purinoceptor 4 0.0276 0.6564 0.8446
Brugia malayi hypothetical protein 0.0019 0.0172 0.0181
Echinococcus multilocularis sodium:hydrogen exchanger 0.0031 0.0467 0.0601
Schistosoma mansoni hypothetical protein 0.0023 0.0266 0.0342
Brugia malayi nuclear hormone receptor 0.0393 0.9477 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0695 0.0733
Loa Loa (eye worm) hypothetical protein 0.0019 0.0172 0.0181
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0172 0.0181
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0695 0.0894
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0172 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0695 0.0733
Echinococcus granulosus tissue type plasminogen activator 0.0023 0.0266 0.0342
Brugia malayi hypothetical protein 0.0021 0.0228 0.024
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0695 0.0894
Schistosoma mansoni P2X receptor subunit 0.0276 0.6564 0.8446
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0324 0.7772 1
Entamoeba histolytica aldose reductase, putative 0.0012 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0021 0.0228 0.024
Schistosoma mansoni P2X receptor subunit 0.0276 0.6564 0.8446
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0172 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0695 0.0733
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0695 0.0733
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0049 0.0922 0.0922
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0025 0.0322 0.0414
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0695 0.0894
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0172 0.0221
Giardia lamblia DNA polymerase alpha subunit A 0.003 0.0455 0.9735
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0012 0 0.5
Brugia malayi conserved hypotetical protein 0.0019 0.0172 0.0181
Echinococcus multilocularis p2X purinoceptor 4 0.0276 0.6564 0.8446
Onchocerca volvulus 0.004 0.0695 0.0695
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0172 0.0221
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0031 0.0467 0.0601

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 150 uM Inhibition of platelet aggregation induced by ADP in rabbit platelet rich plasma ChEMBL. 1654430
EC50 (functional) > 150 uM Inhibition of platelet aggregation induced by collagen in rabbit platelet rich plasma ChEMBL. 1654430
ED50 (functional) NT 0 mg kg-1 Ex vivo inhibition of rat platelet aggregation induced by ADP;Not tested. ChEMBL. 1654430
IC50 (functional) = 20 uM Inhibition of hydrolysis of c-AMP phosphodiesterase in human platelets ChEMBL. 1654430
IC50 (functional) = 20 uM Inhibition of hydrolysis of c-AMP phosphodiesterase in human platelets ChEMBL. 1654430
IC50 (functional) = 60 uM Inhibition of cGMP hydrolysis by human platelet phosphodiesterase ChEMBL. 1654430
IC50 (functional) = 60 uM Inhibition of cGMP hydrolysis by human platelet phosphodiesterase ChEMBL. 1654430

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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