TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 335.385 | Formula: C15H20F3NO2S
H donors: 1 H acceptors: 2 LogP: 3.49 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CCCN[C@H]1CCc2c(C1)cccc2CS(=O)(=O)C(F)(F)F
InChi: 1S/C15H20F3NO2S/c1-2-8-19-13-6-7-14-11(9-13)4-3-5-12(14)10-22(20,21)15(16,17)18/h3-5,13,19H,2,6-10H2,1H3/t13-/m0/s1
InChiKey: NNGXRRFVMCSLCM-ZDUSSCGKSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.005	0.768	1
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.005	0.768	1
Leishmania major	protein kinase, putative	0.005	0.768	0.5
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/ALK protein kinase	0.005	0.768	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Echinococcus multilocularis	protein kinase	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Brugia malayi	hypothetical protein	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Brugia malayi	protein-tyrosine kinase	0.005	0.768	1
Echinococcus granulosus	integrin linked protein kinase	0.005	0.768	1
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.005	0.768	1
Brugia malayi	Furin-like cysteine rich region family protein	0.005	0.768	1
Schistosoma mansoni	serine/threonine protein kinase	0.005	0.768	1
Brugia malayi	Guanylyl cyclase protein 23	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.005	0.768	1
Echinococcus granulosus	tyrosine kinase	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/Met protein kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.005	0.768	1
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.005	0.768	1
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.005	0.768	1
Loa Loa (eye worm)	TK/EPH protein kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.005	0.768	1
Echinococcus granulosus	kinase suppressor of Ras 1	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Echinococcus granulosus	insulin receptor	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Plasmodium falciparum	protein kinase, putative	0.005	0.768	0.5
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/DDR protein kinase	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase shark	0.005	0.768	1
Schistosoma mansoni	ephrin receptor	0.005	0.768	1
Brugia malayi	hypothetical protein	0.005	0.768	1
Schistosoma mansoni	tyrosine protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Src64B	0.005	0.768	1
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.005	0.768	1
Echinococcus granulosus	ephrin type A receptor 4 A	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.005	0.768	1
Echinococcus multilocularis	receptor type guanylyl cyclase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Plasmodium falciparum	protein kinase, putative	0.005	0.768	0.5
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.005	0.768	1
Echinococcus granulosus	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.005	0.768	1
Schistosoma mansoni	protein kinase	0.005	0.768	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.005	0.768	1
Echinococcus multilocularis	kinase suppressor of Ras 1	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase csk	0.005	0.768	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.005	0.768	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.005	0.768	1
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.005	0.768	1
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.005	0.768	1
Echinococcus granulosus	epidermal growth factor receptor	0.005	0.768	1
Trypanosoma brucei	Flagellum attachment zone protein 20	0.005	0.768	0.5
Brugia malayi	Tyrosine-protein kinase abl-1	0.005	0.768	1
Trichomonas vaginalis	TKL family protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/INSR protein kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.005	0.768	1
Giardia lamblia	Protein 21.1	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase csk	0.005	0.768	1
Echinococcus multilocularis	heat shock protein 70	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.005	0.768	1
Echinococcus multilocularis	tyrosine kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Echinococcus multilocularis	protein tyrosine kinase	0.005	0.768	1
Brugia malayi	C-terminal src kinase protein 1	0.005	0.768	1
Plasmodium vivax	tyrosine kinase-like protein, putative	0.005	0.768	0.5
Echinococcus granulosus	retinal guanylyl cyclase 2	0.005	0.768	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.005	0.768	1
Echinococcus granulosus	epidermal growth factor receptor	0.005	0.768	1
Loa Loa (eye worm)	TK/ROR protein kinase	0.005	0.768	1
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Blk	0.005	0.768	1
Schistosoma mansoni	protein kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.005	0.768	1
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.005	0.768	0.5
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.005	0.768	1
Brugia malayi	integrin-linked kinase	0.005	0.768	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.005	0.768	0.5
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Plasmodium vivax	tyrosine kinase-like protein, putative	0.005	0.768	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase csk	0.005	0.768	1
Trypanosoma brucei	Pseudokinase, putative	0.005	0.768	0.5
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.005	0.768	0.5
Echinococcus multilocularis	tyrosine protein kinase pr2	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.005	0.768	1
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.005	0.768	0.5
Schistosoma mansoni	protein kinase	0.005	0.768	1
Schistosoma mansoni	ephrin receptor	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.005	0.768	1
Schistosoma mansoni	protein tyrosine kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.005	0.768	1
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0056	1	1
Schistosoma mansoni	hypothetical protein	0.005	0.768	1
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.005	0.768	1
Brugia malayi	Tyrosine-protein kinase PR2	0.005	0.768	1
Brugia malayi	Raf kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Echinococcus multilocularis	transfer RNA-Thr	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Echinococcus granulosus	raf serine:threonine protein kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.005	0.768	1
Loa Loa (eye worm)	TK/ACK protein kinase	0.005	0.768	1
Echinococcus granulosus	receptor type guanylyl cyclase	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Echinococcus multilocularis	activin receptor type	0.005	0.768	1
Plasmodium falciparum	tyrosine kinase-like protein	0.005	0.768	0.5
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Schistosoma mansoni	serine/threonine protein kinase	0.005	0.768	1
Trichomonas vaginalis	TKL family protein kinase	0.005	0.768	1
Echinococcus multilocularis	raf serine:threonine protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/RYK protein kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.005	0.768	1
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/FAK protein kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.005	0.768	1
Plasmodium vivax	protein kinase, putative	0.005	0.768	0.5
Echinococcus granulosus	tyrosine protein kinase shark	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.005	0.768	1
Brugia malayi	Receptor family ligand binding region containing protein	0.005	0.768	1
Echinococcus multilocularis	FL cytokine receptor	0.005	0.768	1
Trichomonas vaginalis	TKL family protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Echinococcus granulosus	retinal guanylyl cyclase 2	0.005	0.768	1
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.005	0.768	0.5
Loa Loa (eye worm)	RGC/RGC protein kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Srms	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.005	0.768	1
Loa Loa (eye worm)	TK/EGFR protein kinase	0.005	0.768	1
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Lyn	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Echinococcus multilocularis	protein kinase	0.005	0.768	1
Brugia malayi	SH2 domain containing protein	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Trypanosoma cruzi	protein kinase, putative	0.005	0.768	0.5
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.005	0.768	1
Echinococcus multilocularis	protein KINase family member (kin 25)	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.005	0.768	1
Schistosoma mansoni	serine/threonine protein kinase	0.005	0.768	1
Loa Loa (eye worm)	serine/threonine protein kinase	0.005	0.768	1
Echinococcus multilocularis	epidermal growth factor receptor	0.005	0.768	1
Leishmania major	hypothetical protein, conserved	0.005	0.768	0.5
Schistosoma mansoni	protein kinase	0.005	0.768	1
Plasmodium falciparum	tyrosine kinase-like protein	0.005	0.768	0.5
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Echinococcus granulosus	fibroblast growth factor receptor 4	0.005	0.768	1
Echinococcus granulosus	protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Echinococcus granulosus	retinal guanylyl cyclase 2	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Blk	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Echinococcus granulosus	activated cdc42 kinase 1	0.005	0.768	1
Echinococcus granulosus	natriuretic peptide receptor 1	0.005	0.768	1
Echinococcus multilocularis	tyrosine kinase	0.005	0.768	1
Echinococcus multilocularis	insulin receptor	0.005	0.768	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase ABL1	0.005	0.768	1
Trichomonas vaginalis	TKL family protein kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase HCK	0.005	0.768	1
Echinococcus multilocularis	c src tyrosine kinase	0.005	0.768	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.005	0.768	0.5
Toxoplasma gondii	protein kinase domain-containing protein	0.005	0.768	0.5
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Echinococcus multilocularis	natriuretic peptide receptor 1	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/ABL protein kinase	0.005	0.768	1
Echinococcus granulosus	c src tyrosine kinase	0.005	0.768	1
Schistosoma mansoni	protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Onchocerca volvulus		0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.005	0.768	1
Giardia lamblia	Kinase, NEK	0.005	0.768	1
Entamoeba histolytica	protein kinase, putative	0.0056	1	1
Toxoplasma gondii	protein kinase	0.005	0.768	0.5
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Plasmodium falciparum	protein kinase, putative	0.005	0.768	0.5
Leishmania major	protein kinase, putative	0.005	0.768	0.5
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.005	0.768	1
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.005	0.768	1
Echinococcus multilocularis	integrin linked protein kinase	0.005	0.768	1
Entamoeba histolytica	hypothetical protein	0.0056	1	1
Brugia malayi	bone morphogenetic protein type 1 receptor	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Schistosoma mansoni	protein kinase	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Brugia malayi	ephrin receptor 1 precursor	0.005	0.768	1
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Brugia malayi	SH2 domain containing protein	0.005	0.768	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.005	0.768	0.5
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase	0.005	0.768	1
Schistosoma mansoni	protein kinase	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.005	0.768	1
Schistosoma mansoni	protein kinase	0.005	0.768	1
Schistosoma mansoni	protein kinase	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Loa Loa (eye worm)	SRC-1	0.005	0.768	1
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Entamoeba histolytica	hypothetical protein	0.0056	1	1
Echinococcus multilocularis	epidermal growth factor receptor	0.005	0.768	1
Toxoplasma gondii	STE kinase	0.005	0.768	0.5
Echinococcus multilocularis	ephrin type A receptor 4 A	0.005	0.768	1
Echinococcus multilocularis	activated cdc42 kinase 1	0.005	0.768	1
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.005	0.768	1
Loa Loa (eye worm)	TK/FER protein kinase	0.005	0.768	1
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Echinococcus granulosus	protein tyrosine kinase	0.005	0.768	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Srms	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.005	0.768	1
Schistosoma mansoni	serine/threonine RGC	0.005	0.768	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1
Echinococcus granulosus	activin receptor type	0.005	0.768	1
Echinococcus granulosus	activated cdc42 kinase 1	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Loa Loa (eye worm)	TK/CSK protein kinase	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Brugia malayi	hypothetical protein	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase	0.005	0.768	1
Trypanosoma brucei	protein kinase, putative	0.005	0.768	0.5
Schistosoma mansoni	protein kinase	0.005	0.768	1
Trypanosoma cruzi	protein kinase, putative	0.005	0.768	0.5
Loa Loa (eye worm)	hypothetical protein	0.005	0.768	1
Schistosoma mansoni	protein kinase	0.005	0.768	1
Loa Loa (eye worm)	TK protein kinase	0.005	0.768	1
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.005	0.768	1
Brugia malayi	Protein kinase domain containing protein	0.005	0.768	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase Abl	0.005	0.768	1
Loa Loa (eye worm)	protein kinase domain-containing protein	0.005	0.768	1
Brugia malayi	SRC-1	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase HCK	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase pr2	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.005	0.768	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.005	0.768	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.005	0.768	1
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.005	0.768	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.005	0.768	1
Schistosoma mansoni	tyrosine kinase	0.005	0.768	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2028033

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1639394