Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | phd finger protein, putative | 0.0018 | 0.054 | 0.3017 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.054 | 0.054 |
Trypanosoma brucei | unspecified product | 0.0012 | 0.027 | 0.2796 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0258 | 0.0352 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0008 | 0.0093 | 0.0966 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0603 | 0.6236 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.2611 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0006 | 0.0014 | 0.0014 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0015 | 0.0399 | 0.1624 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0011 | 0.0258 | 0.1308 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0018 | 0.054 | 0.054 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0011 | 0.0258 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.3047 | 0.4154 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0168 | 0.7336 | 0.7336 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0168 | 0.7336 | 0.7336 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0168 | 0.7336 | 1 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0006 | 0.0003 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0003 | 0.0004 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0569 | 0.0569 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0012 | 0.027 | 0.0369 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0015 | 0.0399 | 0.0544 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0006 | 0.0014 | 0.0076 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0012 | 0.027 | 0.027 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.2354 | 0.3209 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0011 | 0.0258 | 0.0352 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.001 | 0.0187 | 0.0944 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Schistosoma mansoni | DNA helicase recq5 | 0.0006 | 0.0014 | 0.0014 |
Onchocerca volvulus | Alhambra homolog | 0.0018 | 0.054 | 1 |
Trypanosoma brucei | unspecified product | 0.0008 | 0.0107 | 0.1103 |
Toxoplasma gondii | WD domain, G-beta repeat-containing protein | 0.0006 | 0.0003 | 0.0016 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0258 | 0.2673 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0012 | 0.027 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0006 | 0.0014 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0569 | 0.0776 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.0011 | 0.0258 | 0.0656 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0006 | 0.0014 | 0.0019 |
Brugia malayi | jmjC domain containing protein | 0.0058 | 0.2354 | 0.3209 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0258 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0258 | 0.0352 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0049 | 0.1976 | 0.1976 |
Schistosoma mansoni | hypothetical protein | 0.0006 | 0.0003 | 0.0003 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.2354 | 0.3209 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.1389 | 0.1893 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.2354 | 0.3209 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0012 | 0.027 | 0.027 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0569 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0258 | 0.0352 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0258 | 0.0877 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0049 | 0.1976 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0018 | 0.054 | 0.0736 |
Schistosoma mansoni | hypothetical protein | 0.0227 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0258 | 0.0352 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0064 | 0.2611 | 0.2611 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0603 | 0.6236 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0045 | 0.179 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0569 | 0.0776 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.2611 | 0.2611 |
Echinococcus multilocularis | nibrin | 0.0011 | 0.0258 | 0.0258 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0018 | 0.054 | 0.054 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0012 | 0.027 | 0.2796 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.2611 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0064 | 0.2611 | 0.2611 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0021 | 0.0708 | 0.0708 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1528 | 0.2083 |
Brugia malayi | Bromodomain containing protein | 0.0022 | 0.0726 | 0.099 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.0011 | 0.0258 | 0.5 |
Loa Loa (eye worm) | acetyltransferase | 0.0168 | 0.7336 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0027 | 0.0967 | 0.1318 |
Echinococcus multilocularis | peregrin | 0.0022 | 0.0726 | 0.0726 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Echinococcus granulosus | jumonji domain containing protein | 0.0025 | 0.0852 | 0.0852 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0006 | 0.0003 | 0.0003 |
Toxoplasma gondii | ATPase, AAA family protein | 0.0011 | 0.0258 | 0.1308 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0006 | 0.0014 | 0.0019 |
Echinococcus multilocularis | bloom syndrome protein | 0.0015 | 0.0399 | 0.0399 |
Treponema pallidum | DNA ligase (lig) | 0.0011 | 0.0258 | 0.5 |
Echinococcus multilocularis | dna polymerase eta | 0.0027 | 0.0967 | 0.0967 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0258 | 0.0352 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0011 | 0.0258 | 0.0352 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0012 | 0.027 | 0.0369 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0018 | 0.054 | 0.054 |
Brugia malayi | hypothetical protein | 0.0064 | 0.2611 | 0.356 |
Brugia malayi | AF-10 protein | 0.0006 | 0.0003 | 0.0004 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0258 | 0.0352 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.0011 | 0.0258 | 0.0258 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0011 | 0.0258 | 0.0877 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0006 | 0.0014 | 0.0014 |
Plasmodium vivax | hypothetical protein, conserved | 0.0018 | 0.054 | 0.2733 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0049 | 0.1976 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.111 | 0.1512 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0569 | 0.0569 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0021 | 0.0708 | 0.0708 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.0258 | 0.0656 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0058 | 0.2354 | 0.2354 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0049 | 0.1976 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0569 | 0.0569 |
Giardia lamblia | PHD finger protein 15 | 0.0018 | 0.054 | 0.2963 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0181 | 0.0918 |
Leishmania major | DNA polymerase eta, putative | 0.0027 | 0.0967 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0569 | 0.0569 |
Echinococcus granulosus | dna polymerase kappa | 0.0012 | 0.027 | 0.027 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0018 | 0.054 | 0.2733 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0006 | 0.0003 | 0.0004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0258 | 0.0877 |
Brugia malayi | jmjC domain containing protein | 0.0021 | 0.0708 | 0.0965 |
Schistosoma mansoni | DNA polymerase eta | 0.0027 | 0.0967 | 0.0967 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Chlamydia trachomatis | DNA ligase | 0.0011 | 0.0258 | 0.5 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0015 | 0.0399 | 0.1624 |
Schistosoma mansoni | jumonji domain containing protein | 0.0046 | 0.1817 | 0.1817 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0012 | 0.027 | 0.2796 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0011 | 0.0258 | 0.0877 |
Brugia malayi | topoisomerase | 0.0011 | 0.0258 | 0.0352 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0006 | 0.0014 | 0.0014 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0163 | 0.7123 | 0.7123 |
Giardia lamblia | Replication factor C, subunit 1 | 0.0011 | 0.0258 | 0.1378 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0012 | 0.027 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0021 | 0.0708 | 0.0708 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0011 | 0.0261 | 0.0261 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0008 | 0.0107 | 0.1103 |
Plasmodium vivax | hypothetical protein, conserved | 0.0006 | 0.0003 | 0.0016 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0008 | 0.0107 | 0.1103 |
Brugia malayi | DKFZp564C0469 protein | 0.0011 | 0.0258 | 0.0352 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.0011 | 0.0258 | 0.2673 |
Schistosoma mansoni | DNA helicase recq1 | 0.0006 | 0.0014 | 0.0014 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.1528 | 0.2083 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0006 | 0.0003 | 0.0016 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0012 | 0.027 | 0.0703 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.0011 | 0.0258 | 0.0877 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0012 | 0.027 | 0.5 |
Loa Loa (eye worm) | RecQ helicase | 0.0015 | 0.0399 | 0.0544 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0569 | 0.0569 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0012 | 0.027 | 0.0941 |
Echinococcus granulosus | bloom syndrome protein | 0.0015 | 0.0399 | 0.0399 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0011 | 0.0258 | 0.2673 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.0011 | 0.0258 | 0.1444 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0012 | 0.027 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0227 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0008 | 0.0107 | 0.1103 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0012 | 0.027 | 0.2796 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0569 | 0.0569 |
Brugia malayi | PHD-finger family protein | 0.0018 | 0.054 | 0.0736 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.0011 | 0.0258 | 0.0258 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.1528 | 0.1528 |
Echinococcus granulosus | dna polymerase eta | 0.0027 | 0.0967 | 0.0967 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0012 | 0.027 | 0.027 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0064 | 0.2611 | 0.2611 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0569 | 0.0776 |
Echinococcus granulosus | nibrin | 0.0011 | 0.0258 | 0.0258 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.2611 | 1 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.0011 | 0.0258 | 0.1308 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0569 | 0.0569 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0967 | 0.1318 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0012 | 0.027 | 0.027 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0027 | 0.0967 | 1 |
Schistosoma mansoni | topbp1 | 0.0011 | 0.0258 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.054 | 0.0736 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.0011 | 0.0258 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0569 | 0.0569 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0049 | 0.1976 | 1 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0008 | 0.0093 | 0.0966 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0258 | 0.0877 |
Schistosoma mansoni | DNA ligase IV | 0.0011 | 0.0258 | 0.0258 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0012 | 0.027 | 0.2796 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0012 | 0.027 | 0.0941 |
Brugia malayi | PHD-finger family protein | 0.0006 | 0.0003 | 0.0004 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0027 | 0.0967 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0019 | 0.0603 | 0.3053 |
Echinococcus multilocularis | geminin | 0.0227 | 1 | 1 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0008 | 0.0093 | 0.0966 |
Giardia lamblia | DINP protein human, muc B family | 0.0012 | 0.027 | 0.1446 |
Trypanosoma brucei | unspecified product | 0.0008 | 0.0107 | 0.1103 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0569 | 0.0569 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0569 | 0.0776 |
Echinococcus multilocularis | dna polymerase kappa | 0.0012 | 0.027 | 0.027 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0006 | 0.0014 | 0.0069 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0258 | 0.0877 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0058 | 0.2354 | 0.2354 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0011 | 0.0258 | 0.2673 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0025 | 0.0852 | 0.0852 |
Schistosoma mansoni | topbp1 | 0.0011 | 0.0258 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0258 | 0.0352 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0045 | 0.179 | 1 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0006 | 0.0014 | 0.0014 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0049 | 0.1976 | 1 |
Echinococcus granulosus | replication factor c subunit 1 | 0.0011 | 0.0258 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0014 | 0.0019 |
Entamoeba histolytica | hypothetical protein | 0.0064 | 0.2611 | 1 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0006 | 0.0003 | 0.0034 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0258 | 0.0352 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0021 | 0.0708 | 0.0965 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0018 | 0.054 | 0.2733 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0006 | 0.0014 | 0.0019 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0011 | 0.0258 | 0.2673 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0011 | 0.0258 | 0.0877 |
Leishmania major | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0045 | 0.179 | 0.6737 |
Echinococcus granulosus | peregrin | 0.0022 | 0.0726 | 0.0726 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0021 | 0.0708 | 0.0708 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0012 | 0.027 | 0.2796 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0013 | 0.0319 | 0.1785 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0006 | 0.0003 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.2354 | 0.3209 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 0 % | Antiinflammatory activity in human PMA-stimulated THP1 cells assessed as inhibition of LPS-induced TNFalpha production at 10 uM treated 30 mins before LPS challenge measured after 24 hrs by ELISA | ChEMBL. | 22520258 |
MIC (functional) | = 90 ug ml-1 | Antibacterial activity against Escherichia coli by agar well diffusion method | ChEMBL. | 22520258 |
MIC (functional) | = 90 ug ml-1 | Antifungal activity against Candida albicans by agar well diffusion method | ChEMBL. | 22520258 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.