Detailed information for compound 1643613

Basic information

Technical information
  • TDR Targets ID: 1643613
  • Name: N,N,N',N'-tetrakis(2-chloroethyl)nona-2,7-diy ne-1,9-diamine
  • MW: 400.214 | Formula: C17H26Cl4N2
  • H donors: 0 H acceptors: 0 LogP: 4.25 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClCCN(CC#CCCCC#CCN(CCCl)CCCl)CCCl
  • InChi: 1S/C17H26Cl4N2/c18-8-14-22(15-9-19)12-6-4-2-1-3-5-7-13-23(16-10-20)17-11-21/h1-3,8-17H2
  • InChiKey: BGXBUYYOFKAAGH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 9-[bis(2-chloroethyl)amino]nona-2,7-diynyl-bis(2-chloroethyl)amine
  • NCI60_001364

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.031 0.5853
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Onchocerca volvulus 0.0129 0.3215 1
Onchocerca volvulus 0.0129 0.3215 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0122 0.0205
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0045 0.1027 0.1845
Schistosoma mansoni growth hormone secretagogue receptor 0.0129 0.3215 1
Echinococcus multilocularis neuropeptide Y receptor 0.0129 0.3215 0.3209
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0129 0.3215 0.3209
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus granulosus 7TM GPCR rhodopsin 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni neuropeptide receptor 0.0129 0.3215 1
Brugia malayi neuropeptide F receptor 0.0129 0.3215 0.581
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Echinococcus granulosus neuropeptide s receptor 0.0129 0.3215 0.3209
Echinococcus granulosus neuropeptide Y receptor 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0129 0.3215 0.581
Echinococcus granulosus biogenic amine 5HT receptor 0.0129 0.3215 0.3209
Schistosoma mansoni DNA helicase recq5 0.001 0.0122 0.0379
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni DNA helicase recq1 0.001 0.0122 0.0379
Brugia malayi G protein-coupled receptor F59B2.13 0.0129 0.3215 0.581
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.3215 1
Schistosoma mansoni hypothetical protein 0.0129 0.3215 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0275 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0129 0.3215 1
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni amine GPCR 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0129 0.3215 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0129 0.3215 0.581
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0129 0.3215 1
Echinococcus granulosus survival motor neuron protein 1 0.0219 0.5527 0.5523
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0008 0.0076 0.5
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0129 0.3215 0.3209
Treponema pallidum bacterioferrin (TpF1) 0.0008 0.0076 1
Echinococcus multilocularis neuropeptide receptor A26 0.0129 0.3215 0.3209
Echinococcus granulosus bloom syndrome protein 0.0023 0.0475 0.0467
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni hypothetical protein 0.0129 0.3215 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0129 0.3215 0.581
Onchocerca volvulus 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni hypothetical protein 0.001 0.0144 0.0448
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0009 0.0027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0383 0.1192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis neuropeptide FF receptor 2 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0023 0.0458 0.0814
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0122 0.0205
Schistosoma mansoni hypothetical protein 0.0129 0.3215 1
Onchocerca volvulus 0.0129 0.3215 1
Echinococcus granulosus g protein coupled receptor 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0195 0.2975
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0129 0.3215 0.3209
Schistosoma mansoni biogenic amine receptor 0.0129 0.3215 1
Schistosoma mansoni amine GPCR 0.0129 0.3215 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.001 0.0144 0.0135
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0033 0.0728 0.1304
Schistosoma mansoni amine GPCR 0.0129 0.3215 1
Schistosoma mansoni neuropeptide receptor 0.0129 0.3215 1
Loa Loa (eye worm) neuropeptide F receptor 0.0129 0.3215 0.581
Onchocerca volvulus 0.0129 0.3215 1
Echinococcus multilocularis G protein coupled receptor 139 0.0129 0.3215 0.3209
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0129 0.3215 0.3209
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0195 0.5
Schistosoma mansoni alpha-1 adrenergic receptor 0.0129 0.3215 1
Echinococcus granulosus GPCR family 2 0.001 0.0144 0.0135
Onchocerca volvulus 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0279 0.0489
Loa Loa (eye worm) G-protein coupled receptor 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.001 0.0144 0.0135
Schistosoma mansoni opsin-like receptor 0.0129 0.3215 1
Brugia malayi G-protein coupled receptor 0.0129 0.3215 0.581
Echinococcus multilocularis G-protein coupled receptor, putative 0.0129 0.3215 0.3209
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0392 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.3215 1
Mycobacterium ulcerans bacterioferritin BfrA 0.0008 0.0076 0.5
Echinococcus granulosus g-protein coupled receptor 0.0129 0.3215 0.3209
Schistosoma mansoni hypothetical protein 0.001 0.0144 0.0448
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0129 0.3215 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) G-protein coupled receptor 0.0129 0.3215 0.581
Echinococcus granulosus ferritin 0.0008 0.0076 0.0067
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.034 0.0332
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Echinococcus granulosus neuropeptides capa receptor 0.0129 0.3215 0.3209
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Onchocerca volvulus 0.0129 0.3215 1
Echinococcus multilocularis neuropeptide s receptor 0.0129 0.3215 0.3209
Echinococcus multilocularis neuropeptides capa receptor 0.0129 0.3215 0.3209
Brugia malayi RE15519p 0.0129 0.3215 0.581
Brugia malayi latrophilin 2 splice variant baaae 0.0023 0.0458 0.0814
Echinococcus multilocularis neuropeptides capa receptor 0.0129 0.3215 0.3209
Schistosoma mansoni amine GPCR 0.0129 0.3215 1
Brugia malayi Dopamine receptor protein 1 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0129 0.3215 0.581
Loa Loa (eye worm) RecQ helicase 0.0023 0.0475 0.0845
Echinococcus granulosus orexin receptor type 2 0.0129 0.3215 0.3209
Echinococcus multilocularis dro:myosuppressin receptor 0.0129 0.3215 0.3209
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.031 0.5853
Schistosoma mansoni neuropeptide F-like receptor 0.0129 0.3215 1
Schistosoma mansoni apoferritin-2 0.0008 0.0076 0.0237
Brugia malayi AKH receptor 0.0129 0.3215 0.581
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0129 0.3215 1
Echinococcus multilocularis neuropeptide Y receptor 0.0129 0.3215 0.3209
Schistosoma mansoni hypothetical protein 0.0129 0.3215 1
Schistosoma mansoni ferritin 0.0008 0.0076 0.0237
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus granulosus neuropeptide receptor A26 0.0129 0.3215 0.3209
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Brugia malayi GnHR receptor homolog 0.0129 0.3215 0.581
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0475 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni apoferritin-2 0.0008 0.0076 0.0237
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.3215 1
Echinococcus granulosus neuropeptide receptor 0.0129 0.3215 0.3209
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0129 0.3215 0.3209
Schistosoma mansoni hypothetical protein 0.0045 0.1027 0.3193
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Echinococcus granulosus neuropeptide Y receptor 0.0129 0.3215 0.3209
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0018 0.034 0.0601
Echinococcus granulosus allatostatin A receptor 0.0129 0.3215 0.3209
Giardia lamblia Sgs1 DNA helicase, putative 0.001 0.0122 0.5
Mycobacterium ulcerans bacterioferritin BfrB 0.0008 0.0076 0.5
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) neuropeptide F receptor 0.0129 0.3215 0.581
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0033 0.0728 0.1304
Echinococcus multilocularis neuropeptide receptor 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0129 0.3215 0.3209
Echinococcus multilocularis orexin receptor type 2 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0117 0.2901 0.5242
Brugia malayi hypothetical protein 0.0219 0.5527 1
Brugia malayi Dopamine receptor protein 2 0.0129 0.3215 0.581
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.001 0.0144 0.0245
Echinococcus multilocularis g-protein coupled receptor 0.0129 0.3215 0.3209
Echinococcus granulosus 7tm_1 domain containing protein 0.0129 0.3215 0.3209
Echinococcus multilocularis g protein coupled receptor 0.0129 0.3215 0.3209
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.001 0.0144 0.0135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) melatonin receptor type 1A 0.0129 0.3215 0.581
Echinococcus multilocularis g protein coupled receptor 0.0129 0.3215 0.3209
Echinococcus granulosus serotonin receptor 0.0129 0.3215 0.3209
Schistosoma mansoni opsin-like receptor 0.0129 0.3215 1
Brugia malayi G-protein coupled receptor 0.0129 0.3215 0.581
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0129 0.3215 0.3209
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0129 0.3215 0.3209
Onchocerca volvulus 0.0129 0.3215 1
Schistosoma mansoni ferritin 0.0008 0.0076 0.0237
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0129 0.3215 0.3209
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Schistosoma mansoni neuropeptide receptor 0.0129 0.3215 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0129 0.3215 0.581
Schistosoma mansoni ferritin 0.0008 0.0076 0.0237
Schistosoma mansoni biogenic amine (5HT) receptor 0.0129 0.3215 1
Schistosoma mansoni opsin-like receptor 0.0129 0.3215 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0348 0.1084
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0129 0.3215 0.3209
Brugia malayi Serotonin receptor 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0033 0.0728 0.1304
Schistosoma mansoni survival motor neuron protein 0.0045 0.1027 0.3193
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.3215 1
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Brugia malayi putative neuropeptide receptor 0.0129 0.3215 0.581
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0008 0.0076 0.5
Schistosoma mansoni histamine h1 receptor 0.0129 0.3215 1
Onchocerca volvulus 0.0129 0.3215 1
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) TYRA-2 protein 0.0129 0.3215 0.581
Echinococcus multilocularis sex peptide receptor 0.0129 0.3215 0.3209
Schistosoma mansoni neuropeptide receptor 0.0129 0.3215 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0129 0.3215 0.3209
Brugia malayi neuropeptide F receptor 0.0129 0.3215 0.581
Echinococcus multilocularis somatostatin receptor 0.0129 0.3215 0.3209
Schistosoma mansoni hypothetical protein 0.001 0.0144 0.0448
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0018 0.034 0.0601
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0383 0.1192
Brugia malayi Serotonin receptor 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0122 0.0113
Echinococcus granulosus sex peptide receptor 0.0129 0.3215 0.3209
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0129 0.3215 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Echinococcus granulosus tm gpcr rhodopsin 0.0129 0.3215 0.3209
Onchocerca volvulus 0.0129 0.3215 1
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0122 0.0113
Brugia malayi larval opioid receptor 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis survival motor neuron protein 1 0.0219 0.5527 0.5523
Brugia malayi sulfakinin receptor protein 0.0129 0.3215 0.581
Echinococcus multilocularis g protein coupled receptor 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Brugia malayi Calcitonin receptor-like protein seb-1 0.0033 0.0728 0.1304
Echinococcus granulosus g protein coupled receptor 0.0129 0.3215 0.3209
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0129 0.3215 0.581
Echinococcus multilocularis neuropeptide receptor 0.0129 0.3215 0.3209
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0129 0.3215 0.3209
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0122 0.4422
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0129 0.3215 1
Brugia malayi G protein-coupled receptor 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis fmrfamide receptor 0.0129 0.3215 0.3209
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0129 0.3215 0.3209
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0129 0.3215 0.3209
Echinococcus granulosus g protein coupled receptor 0.0129 0.3215 0.3209
Onchocerca volvulus 0.0129 0.3215 1
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0195 1
Echinococcus multilocularis ferritin 0.0008 0.0076 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0122 0.0113
Echinococcus granulosus alpha 1A adrenergic receptor 0.0129 0.3215 0.3209
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0122 0.0113
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0008 0.0076 0.5
Schistosoma mansoni ferritin light chain 0.0008 0.0076 0.0237
Onchocerca volvulus 0.0129 0.3215 1
Schistosoma mansoni amine GPCR 0.0129 0.3215 1
Echinococcus granulosus somatostatin receptor 0.0129 0.3215 0.3209
Echinococcus multilocularis serotonin receptor 0.0129 0.3215 0.3209
Echinococcus granulosus neuropeptide receptor 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis fmrfamide receptor 0.0129 0.3215 0.3209
Loa Loa (eye worm) latrophilin receptor protein 2 0.001 0.0144 0.0245
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0122 0.0205
Schistosoma mansoni biogenic amine (5HT) receptor 0.0129 0.3215 1
Schistosoma mansoni neuropeptide F-like receptor 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.3215 1
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0475 0.0467
Echinococcus multilocularis GPCR, family 2 0.001 0.0144 0.0135
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus granulosus neuropeptide FF receptor 2 0.0129 0.3215 0.3209
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0129 0.3215 0.581
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Brugia malayi putative neuropeptide receptor NPR1 0.0129 0.3215 0.581
Schistosoma mansoni hypothetical protein 0.001 0.0144 0.0448
Onchocerca volvulus Neuropeptide F receptor homolog 0.0129 0.3215 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0129 0.3215 0.3209
Brugia malayi Melatonin receptor type 1A 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0219 0.5527 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0129 0.3215 0.3209
Schistosoma mansoni myosin xvIII 0.0129 0.3215 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0129 0.3215 0.3209
Brugia malayi ORL1-like opioid receptor 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis allatostatin A receptor 0.0129 0.3215 0.3209
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0195 0.5
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Onchocerca volvulus 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0144 0.0245
Brugia malayi Latrophilin receptor protein 2 0.001 0.0144 0.0245
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus granulosus expressed protein 0.0008 0.0076 0.0067
Echinococcus granulosus G protein coupled receptor 139 0.0129 0.3215 0.3209
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis expressed protein 0.0008 0.0076 0.0067
Brugia malayi Dopamine receptor 0.0129 0.3215 0.581
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.001 0.0144 0.0135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.3215 1
Schistosoma mansoni ferritin 0.0008 0.0076 0.0237
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0129 0.3215 1
Echinococcus granulosus tm gpcr rhodopsin 0.0129 0.3215 0.3209
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0475 1
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0122 0.4422
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Echinococcus multilocularis serotonin receptor 0.0129 0.3215 0.3209
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0008 0.0076 0.5
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Brugia malayi follicle stimulating hormone receptor 0.0129 0.3215 0.581
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.034 0.0332
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0129 0.3215 0.3209
Schistosoma mansoni biogenic amine receptor 0.0129 0.3215 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0122 0.0205
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0195 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0129 0.3215 1
Echinococcus granulosus hypothetical protein 0.0129 0.3215 0.3209
Onchocerca volvulus 0.0129 0.3215 1
Schistosoma mansoni adenoreceptor 0.0129 0.3215 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0129 0.3215 0.581
Echinococcus granulosus tm gpcr rhodopsin 0.0129 0.3215 0.3209
Echinococcus granulosus neuropeptides capa receptor 0.0129 0.3215 0.3209
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0475 0.0845
Schistosoma mansoni hypothetical protein 0.0023 0.0458 0.1424
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0129 0.3215 0.581
Loa Loa (eye worm) hypothetical protein 0.0129 0.3215 0.581
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.028 0.5
Echinococcus granulosus dro:myosuppressin receptor 0.0129 0.3215 0.3209
Schistosoma mansoni biogenic amine receptor 0.0129 0.3215 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0129 0.3215 0.3209
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Onchocerca volvulus 0.0129 0.3215 1
Brugia malayi hypothetical protein 0.0129 0.3215 0.581
Schistosoma mansoni ferritin light chain 0.0008 0.0076 0.0237
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Onchocerca volvulus 0.0129 0.3215 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0129 0.3215 0.581
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0402 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.3215 0.3209
Onchocerca volvulus 0.0129 0.3215 1
Echinococcus granulosus fmrfamide receptor 0.0129 0.3215 0.3209

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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