Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0164 | 1 | 1 |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 1 | 1 |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0095 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0164 | 1 | 1 |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0164 | 1 | 1 |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0164 | 1 | 1 |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0164 | 1 | 1 |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Echinococcus granulosus | carboxylesterase 5A | 0.0164 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0164 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 1 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0095 | 0 | 0.5 |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0164 | 1 | 1 |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Onchocerca volvulus | 0.0095 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0164 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0164 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.