Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0139 | 0.3146 | 0.2239 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0139 | 0.3146 | 0.3146 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0065 | 0.1296 | 0.0171 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0139 | 0.3146 | 0.2239 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0139 | 0.3146 | 0.2686 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0139 | 0.3146 | 0.3146 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0139 | 0.3146 | 0.2686 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Onchocerca volvulus | 0.0139 | 0.3146 | 0.252 | |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1494 | 0.0367 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0139 | 0.3146 | 0.2239 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0139 | 0.3146 | 0.2239 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0065 | 0.1296 | 0.0143 |
Echinococcus granulosus | NDR protein kinase | 0.0061 | 0.117 | 0.117 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0152 | 0.3478 | 0.2614 |
Brugia malayi | nuclear receptor NHR-88 | 0.0065 | 0.1296 | 0.0171 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | nuclear receptor NHR-67 | 0.0065 | 0.1296 | 0.0171 |
Schistosoma mansoni | nuclear receptor | 0.0065 | 0.1296 | 0.0143 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0065 | 0.1296 | 0.0171 |
Loa Loa (eye worm) | CMGC/CK2 protein kinase | 0.0132 | 0.2972 | 0.2041 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0139 | 0.3146 | 0.2686 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0065 | 0.1296 | 0.0143 |
Brugia malayi | nuclear receptor NHR-88 | 0.0139 | 0.3146 | 0.2686 |
Brugia malayi | conserved hypotetical protein | 0.0065 | 0.1296 | 0.0171 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0139 | 0.3146 | 0.252 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0139 | 0.3146 | 0.3146 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0139 | 0.3146 | 0.2239 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1494 | 0.0367 |
Brugia malayi | nuclear hormone receptor | 0.0139 | 0.3146 | 0.2686 |
Giardia lamblia | Kinase, AGC AKT | 0.0352 | 0.8528 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0139 | 0.3146 | 0.3146 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0139 | 0.3146 | 0.252 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0139 | 0.3146 | 0.2239 |
Schistosoma mansoni | zinc finger protein | 0.0065 | 0.1296 | 0.0143 |
Schistosoma mansoni | serine/threonine protein kinase | 0.041 | 1 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0132 | 0.2972 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0139 | 0.3146 | 0.2239 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0152 | 0.3478 | 0.2614 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0152 | 0.3478 | 0.3478 |
Brugia malayi | hypothetical protein | 0.0073 | 0.1494 | 0.044 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0073 | 0.1494 | 0.0367 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0152 | 0.3478 | 0.2614 |
Schistosoma mansoni | nuclear receptor | 0.0065 | 0.1296 | 0.0143 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0139 | 0.3146 | 0.2239 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3146 | 0.2239 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0073 | 0.1494 | 0.0367 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0073 | 0.1494 | 0.0367 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0139 | 0.3146 | 0.3146 |
Brugia malayi | hypothetical protein | 0.0073 | 0.1494 | 0.044 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0139 | 0.3146 | 0.2686 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3146 | 0.2239 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0073 | 0.1494 | 0.1494 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0065 | 0.1296 | 0.0143 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0065 | 0.1296 | 0.1296 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | tailless protein | 0.0065 | 0.1296 | 0.0171 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0097 | 0.21 | 0.5164 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3146 | 0.2239 |
Echinococcus granulosus | protein kinase C gamma type | 0.0061 | 0.117 | 0.117 |
Schistosoma mansoni | nuclear hormone receptor | 0.0139 | 0.3146 | 0.2239 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0065 | 0.1296 | 0.0143 |
Brugia malayi | nuclear hormone receptor | 0.0065 | 0.1296 | 0.0171 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0139 | 0.3146 | 0.2686 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0152 | 0.3478 | 0.3137 |
Onchocerca volvulus | Telomerase reverse transcriptase homolog | 0.0357 | 0.864 | 1 |
Leishmania major | rac serine-threonine kinase, putative,protein kinase, putative | 0.0352 | 0.8528 | 1 |
Brugia malayi | ribosomal protein S6 kinase alpha 3 | 0.0352 | 0.8528 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0065 | 0.1296 | 0.0143 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0139 | 0.3146 | 0.2239 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0097 | 0.21 | 0.5164 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0073 | 0.1494 | 0.044 |
Brugia malayi | steroid hormone receptor | 0.0139 | 0.3146 | 0.2686 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0132 | 0.2972 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0139 | 0.3146 | 0.2239 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0065 | 0.1296 | 0.0143 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0152 | 0.3478 | 0.2614 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0139 | 0.3146 | 0.2686 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0139 | 0.3146 | 0.2239 |
Leishmania major | casein kinase II, putative | 0.0132 | 0.2972 | 0.1356 |
Brugia malayi | ecdysone receptor | 0.0065 | 0.1296 | 0.0171 |
Schistosoma mansoni | nuclear hormone receptor | 0.0065 | 0.1296 | 0.0143 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0139 | 0.3146 | 0.252 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0132 | 0.2972 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0139 | 0.3146 | 0.2686 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1494 | 0.0367 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0065 | 0.1296 | 0.0143 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0065 | 0.1296 | 0.0171 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0065 | 0.1296 | 0.0143 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0132 | 0.2972 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0139 | 0.3146 | 0.2239 |
Plasmodium vivax | casein kinase 2, alpha subunit, putative | 0.0132 | 0.2972 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | nuclear receptor RXR | 0.0073 | 0.1494 | 0.044 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0139 | 0.3146 | 0.2686 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0139 | 0.3146 | 0.2686 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0139 | 0.3146 | 0.2239 |
Schistosoma mansoni | nuclear hormone receptor | 0.0065 | 0.1296 | 0.0143 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0065 | 0.1296 | 0.0171 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0065 | 0.1296 | 0.0143 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Echinococcus granulosus | FTZ F1 alpha | 0.0139 | 0.3146 | 0.3146 |
Brugia malayi | hypothetical protein | 0.0065 | 0.1296 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3146 | 0.2239 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0139 | 0.3146 | 0.2686 |
Brugia malayi | nuclear receptor RXR | 0.0065 | 0.1296 | 0.0171 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0139 | 0.3146 | 0.2239 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0139 | 0.3146 | 0.2239 |
Toxoplasma gondii | CMGC kinase, CK2 family | 0.0132 | 0.2972 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0132 | 0.2972 | 1 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.041 | 1 | 1 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0061 | 0.117 | 0.117 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0065 | 0.1296 | 0.1296 |
Trypanosoma cruzi | casein kinase II, putative | 0.0132 | 0.2972 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0139 | 0.3146 | 0.2686 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0139 | 0.3146 | 0.2239 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0061 | 0.117 | 0.117 |
Brugia malayi | Casein kinase II, alpha chain | 0.0132 | 0.2972 | 0.2449 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3146 | 0.2239 |
Schistosoma mansoni | thyroid hormone receptor | 0.0139 | 0.3146 | 0.2239 |
Plasmodium vivax | unspecified product | 0.0132 | 0.2972 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0139 | 0.3146 | 0.2239 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0139 | 0.3146 | 0.2686 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0139 | 0.3146 | 0.2239 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3146 | 0.2239 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0065 | 0.1296 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0139 | 0.3146 | 0.3146 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.041 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0139 | 0.3146 | 0.2686 |
Loa Loa (eye worm) | DR-78 | 0.0065 | 0.1296 | 0.0143 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0061 | 0.117 | 0.117 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0139 | 0.3146 | 0.2686 |
Schistosoma mansoni | coup transcription factor | 0.0139 | 0.3146 | 0.2239 |
Trichomonas vaginalis | AGC family protein kinase | 0.0061 | 0.117 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0065 | 0.1296 | 0.0171 |
Schistosoma mansoni | thyroid hormone receptor | 0.0139 | 0.3146 | 0.2239 |
Brugia malayi | ecdysteroid receptor | 0.0139 | 0.3146 | 0.2686 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0132 | 0.2972 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0132 | 0.2972 | 1 |
Giardia lamblia | Kinase, CMGC CK2 | 0.0132 | 0.2972 | 0.1356 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0073 | 0.1494 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1494 | 0.0367 |
Trypanosoma brucei | Casein kinase II | 0.0132 | 0.2972 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0065 | 0.1296 | 0.0143 |
Plasmodium falciparum | casein kinase 2, alpha subunit | 0.0132 | 0.2972 | 1 |
Echinococcus multilocularis | casein kinase ii subunit alpha | 0.0132 | 0.2972 | 0.2041 |
Brugia malayi | hypothetical protein | 0.0065 | 0.1296 | 0.0171 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0065 | 0.1296 | 0.0171 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0139 | 0.3146 | 0.2686 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0065 | 0.1296 | 0.1296 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0065 | 0.1296 | 0.0143 |
Brugia malayi | Telomerase reverse transcriptase | 0.0259 | 0.6182 | 0.6812 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1494 | 0.0367 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0065 | 0.1296 | 0.1296 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Echinococcus granulosus | protein kinase c iota type | 0.0061 | 0.117 | 0.117 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0065 | 0.1296 | 0.1296 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0061 | 0.117 | 0.117 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0139 | 0.3146 | 0.3146 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0061 | 0.117 | 0.117 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0139 | 0.3146 | 0.2686 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0139 | 0.3146 | 0.2239 |
Entamoeba histolytica | casein kinase, putative | 0.0132 | 0.2972 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0132 | 0.2972 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0139 | 0.3146 | 0.3146 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0073 | 0.1494 | 0.0367 |
Echinococcus granulosus | casein kinase ii subunit alpha | 0.0132 | 0.2972 | 0.2972 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1296 | 0.0143 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0065 | 0.1296 | 0.1296 |
Schistosoma mansoni | protein kinase | 0.0132 | 0.2972 | 0.2041 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -8.811 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8.276 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8.15 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8.091 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7.993 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7.981 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7.973 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7.924 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7.918 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7.456 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.834 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.