Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.2583 | 1 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0012 | 0.0022 | 0.0066 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0015 | 0.0194 | 0.0182 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.2718 | 0.2709 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0015 | 0.0194 | 0.0708 |
Leishmania major | trypanothione reductase | 0.0045 | 0.1574 | 0.6059 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Brugia malayi | RNA binding protein | 0.0069 | 0.2718 | 0.4491 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0015 | 0.0194 | 0.1166 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0194 | 0.1166 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0012 | 0.0022 | 0.0066 |
Treponema pallidum | NADH oxidase | 0.0015 | 0.0194 | 0.4367 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0429 | 0.267 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2718 | 0.2709 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0012 | 0.0022 | 0.0066 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0015 | 0.0194 | 0.4367 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0066 | 0.2583 | 0.2574 |
Plasmodium falciparum | thioredoxin reductase | 0.0045 | 0.1574 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0045 | 0.1574 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0045 | 0.1574 | 0.1564 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0015 | 0.0194 | 0.1166 |
Plasmodium falciparum | glutathione reductase | 0.0015 | 0.0194 | 0.1166 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0015 | 0.0194 | 0.1166 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0015 | 0.0194 | 0.0321 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0194 | 0.1166 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0429 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0012 | 0.0022 | 0.0037 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0012 | 0.0022 | 0.001 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0012 | 0.0022 | 0.0066 |
Mycobacterium tuberculosis | Probable reductase | 0.0102 | 0.4279 | 0.8837 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2718 | 0.2709 |
Echinococcus granulosus | lamin | 0.0032 | 0.0968 | 0.0957 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0194 | 0.1166 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0968 | 0.0957 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0012 | 0.0022 | 0.001 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0333 | 0.0322 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.2214 | 0.2205 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.2214 | 0.2205 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0429 | 0.267 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0012 | 0.0022 | 0.0248 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0333 | 0.0322 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0429 | 0.0418 |
Echinococcus multilocularis | musashi | 0.0032 | 0.0968 | 0.0957 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0012 | 0.0022 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.001 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.2214 | 0.3659 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.1344 | 0.1333 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0015 | 0.0194 | 0.0182 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0333 | 0.0322 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0429 | 0.0418 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0223 | 1 | 1 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0012 | 0.0022 | 0.0066 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0012 | 0.0012 | 0.002 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0012 | 0.002 |
Onchocerca volvulus | 0.0012 | 0.0022 | 0.0108 | |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0015 | 0.0194 | 0.0708 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0333 | 0.0322 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0015 | 0.0194 | 0.0182 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0012 | 0.0022 | 0.001 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0429 | 0.1622 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0429 | 0.0418 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0429 | 0.267 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0333 | 0.0551 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0333 | 0.0322 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0333 | 0.0322 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0429 | 1 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0012 | 0.0022 | 0.001 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0102 | 0.4279 | 0.8837 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0012 | 0.0022 | 0.0066 |
Onchocerca volvulus | 0.0012 | 0.0022 | 0.0108 | |
Echinococcus multilocularis | lamin | 0.0032 | 0.0968 | 0.0957 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0102 | 0.4279 | 0.8881 |
Schistosoma mansoni | lamin | 0.0032 | 0.0968 | 0.0957 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0066 | 0.2583 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0015 | 0.0194 | 0.0671 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0015 | 0.0194 | 0.1166 |
Trypanosoma brucei | trypanothione reductase | 0.0045 | 0.1574 | 1 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0223 | 1 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0429 | 0.267 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0015 | 0.0194 | 0.4367 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0022 | 0.0037 |
Echinococcus granulosus | lamin dm0 | 0.0032 | 0.0968 | 0.0957 |
Echinococcus granulosus | aminopeptidase N | 0.0012 | 0.0022 | 0.001 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0066 | 0.2583 | 0.2574 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0189 | 0.0177 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0429 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0333 | 0.0322 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0161 | 0.015 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0012 | 0.0022 | 0.0066 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0333 | 0.0322 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0045 | 0.1574 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0194 | 0.1166 |
Brugia malayi | glutathione reductase | 0.0045 | 0.1574 | 0.26 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0429 | 0.0709 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0429 | 0.0418 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0012 | 0.0022 | 0.004 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0012 | 0.002 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0015 | 0.0194 | 0.1166 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0012 | 0.0022 | 0.004 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0012 | 0.0022 | 0.004 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0012 | 0.0022 | 0.0248 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.2583 | 0.2574 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0022 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.001 |
Plasmodium vivax | glutathione reductase, putative | 0.0045 | 0.1574 | 1 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0012 | 0.0022 | 0.004 |
Plasmodium falciparum | thioredoxin reductase | 0.0015 | 0.0194 | 0.1166 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0012 | 0.0022 | 0.001 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.0269 | 0.0444 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0012 | 0.0022 | 0.0066 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0113 | 0.4816 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0102 | 0.4279 | 0.8837 |
Loa Loa (eye worm) | aminopeptidase N | 0.0012 | 0.0022 | 0.001 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0012 | 0.0022 | 0.001 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0015 | 0.0189 | 0.0177 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.2214 | 0.3659 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0015 | 0.0189 | 0.0177 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0015 | 0.0194 | 0.0671 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0429 | 0.0508 |
Onchocerca volvulus | 0.0012 | 0.0022 | 0.0108 | |
Echinococcus granulosus | intermediate filament protein | 0.0032 | 0.0968 | 0.0957 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0015 | 0.0194 | 0.4367 |
Brugia malayi | Thioredoxin reductase | 0.0045 | 0.1574 | 0.26 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0012 | 0.0022 | 0.0066 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0012 | 0.0022 | 0.0066 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0429 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0012 | 0.0022 | 0.0037 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0032 | 0.0968 | 0.0957 |
Onchocerca volvulus | 0.0032 | 0.0968 | 1 | |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0045 | 0.1602 | 0.1592 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0333 | 0.0322 |
Brugia malayi | DKFZp564C0469 protein | 0.0012 | 0.0012 | 0.002 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.2718 | 0.2709 |
Brugia malayi | intermediate filament protein | 0.0032 | 0.0968 | 0.1599 |
Plasmodium falciparum | glutathione reductase | 0.0045 | 0.1574 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.2718 | 0.2709 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2718 | 0.2709 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0066 | 0.2583 | 0.5169 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Brugia malayi | TATA binding protein associated factor | 0.0012 | 0.0022 | 0.0037 |
Schistosoma mansoni | lamin | 0.0032 | 0.0968 | 0.0957 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0015 | 0.0194 | 0.1166 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0102 | 0.4279 | 0.8837 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0269 | 0.0257 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0015 | 0.0194 | 0.1166 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0102 | 0.4279 | 0.8837 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0015 | 0.0194 | 0.1166 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0102 | 0.4279 | 0.8837 |
Loa Loa (eye worm) | intermediate filament protein | 0.0032 | 0.0968 | 0.0957 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0015 | 0.0194 | 0.1166 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.001 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.2583 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0045 | 0.1574 | 0.1564 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0429 | 0.0418 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0194 | 0.0671 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0223 | 1 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0429 | 0.1588 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.2718 | 0.2709 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0113 | 0.4816 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0066 | 0.2583 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0015 | 0.0194 | 0.1166 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0045 | 0.1574 | 0.2985 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.014 | 0.6053 | 0.6048 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0015 | 0.0194 | 0.0708 |
Toxoplasma gondii | thioredoxin reductase | 0.0045 | 0.1574 | 0.6074 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0045 | 0.1602 | 0.1592 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0066 | 0.2583 | 0.2574 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0012 | 0.0022 | 0.0248 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0015 | 0.0194 | 0.4367 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.2718 | 0.4491 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0012 | 0.0022 | 0.001 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.2718 | 0.2709 |
Onchocerca volvulus | 0.0032 | 0.0968 | 1 | |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0012 | 0.0022 | 0.0066 |
Echinococcus multilocularis | aminopeptidase N | 0.0012 | 0.0022 | 0.001 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0015 | 0.0194 | 0.0708 |
Trypanosoma brucei | aminopeptidase, putative | 0.0012 | 0.0022 | 0.0066 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0333 | 0.0322 |
Entamoeba histolytica | aminopeptidase, putative | 0.0012 | 0.0022 | 0.0248 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0429 | 0.1622 |
Toxoplasma gondii | aminopeptidase N protein | 0.0012 | 0.0022 | 0.004 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.1344 | 0.222 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0333 | 0.0551 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0194 | 0.1166 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0015 | 0.0194 | 0.0708 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.2718 | 0.4491 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0012 | 0.0022 | 0.0066 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0015 | 0.0194 | 0.4367 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0015 | 0.0194 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0066 | 0.2583 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2718 | 0.2709 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0015 | 0.0194 | 0.1166 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.094 | 0.0929 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0429 | 1 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0012 | 0.0012 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1344 | 0.1333 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0194 | 0.0671 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.0022 | 0.001 |
Brugia malayi | hypothetical protein | 0.0103 | 0.4307 | 0.7116 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0032 | 0.0968 | 0.1599 |
Schistosoma mansoni | intermediate filament proteins | 0.0032 | 0.0968 | 0.0957 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0429 | 0.267 |
Brugia malayi | topoisomerase | 0.0012 | 0.0012 | 0.002 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.0194 | 0.1166 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0012 | 0.0022 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0161 | 0.015 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0333 | 0.0322 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2718 | 0.2709 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0333 | 0.0322 |
Echinococcus multilocularis | lamin dm0 | 0.0032 | 0.0968 | 0.0957 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0429 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0012 | 0.0022 | 0.0037 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0012 | 0.0022 | 0.0066 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0113 | 0.4816 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.014 | 0.6053 | 0.6048 |
Brugia malayi | MH2 domain containing protein | 0.014 | 0.6053 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0113 | 0.4816 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.844 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.789 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.785 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.771 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.762 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.732 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.721 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.704 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.694 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.653 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.