Detailed information for compound 1650263

Basic information

Technical information
  • TDR Targets ID: 1650263
  • Name: 1,3-dibromo-5,5-dihydroxycyclopenta[c]thiophe ne-4,6-dione
  • MW: 341.961 | Formula: C7H2Br2O4S
  • H donors: 2 H acceptors: 4 LogP: 1.79 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1c2c(Br)sc(c2C(=O)C1(O)O)Br
  • InChi: 1S/C7H2Br2O4S/c8-5-1-2(6(9)14-5)4(11)7(12,13)3(1)10/h12-13H
  • InChiKey: CPYBQJIFYCVZDC-UHFFFAOYSA-N  

Network

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Synonyms

  • 1,3-dibromo-5,5-dihydroxy-cyclopenta[c]thiophene-4,6-dione
  • 1,3-dibromo-5,5-dihydroxy-cyclopenta[c]thiophene-4,6-quinone
  • NCI60_038998
  • NSC710884

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0022 0.0008 0.0037
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0282 0.0316 0.039
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0464 0.0532 0.0532
Echinococcus multilocularis FTZ F1 alpha 0.0098 0.0098 0.0121
Onchocerca volvulus 0.0057 0.005 0.0047
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Giardia lamblia Kinase, PLK 0.1428 0.1676 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.4185 0.4945 0.558
Echinococcus multilocularis zinc finger protein 0.0038 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0277 0.0311 0.0351
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.3577 0.4224 0.5362
Entamoeba histolytica presenilin 1 peptidase, putative 0.0116 0.0119 0.0692
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0022 0.0117
Echinococcus multilocularis dna polymerase eta 0.0033 0.0022 0.0026
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.002 0.0005 0.0019
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0293 0.0329 0.0377
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0062 0.0056 0.0063
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0464 0.0532 0.0676
Plasmodium vivax CDK-related protein kinase 6, putative 0.0351 0.0398 0.3021
Echinococcus multilocularis jumonji domain containing protein 0.0029 0.0016 0.002
Echinococcus multilocularis replication factor c subunit 1 0.0032 0.002 0.0024
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0277 0.0311 0.1852
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0098 0.0098 0.0098
Echinococcus multilocularis g protein coupled receptor 0.0164 0.0177 0.0218
Echinococcus granulosus lysyl tRNA synthetase 0.0018 0.0003 0.0005
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.1121 0.1311 0.162
Echinococcus multilocularis segment polarity protein dishevelled 0.0032 0.002 0.0024
Mycobacterium tuberculosis Conserved protein 0.0031 0.0019 0.0024
Echinococcus granulosus importin subunit beta 1 0.0036 0.0025 0.0039
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0037 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Echinococcus multilocularis son of sevenless 1 0.0023 0.0009 0.0011
Brugia malayi MH1 domain containing protein 0.0017 0.0002 0.0002
Echinococcus granulosus g-protein coupled receptor 0.0164 0.0177 0.0279
Toxoplasma gondii ATPase, AAA family protein 0.0032 0.002 0.0032
Brugia malayi Neuronal symmetry protein 1 0.3668 0.4331 0.4331
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0035 0.0024 0.0037
Brugia malayi jmjC domain containing protein 0.003 0.0017 0.0017
Brugia malayi RNA recognition motif domain containing protein 0.0288 0.0323 0.0323
Brugia malayi T-complex protein 1, beta subunit 0.0022 0.0008 0.0008
Onchocerca volvulus Alhambra homolog 0.0021 0.0007 0.0002
Leishmania major isocitrate dehydrogenase, putative 0.0024 0.001 0.005
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0271 0.0304 0.0385
Loa Loa (eye worm) MH2 domain-containing protein 0.0031 0.0018 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0031 0.0019 0.0021
Trichomonas vaginalis pyruvate kinase, putative 0.0029 0.0017 0.0096
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trypanosoma cruzi importin beta-1 subunit, putative 0.003 0.0017 0.009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0098 0.0098 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0166 0.0179 0.0205
Schistosoma mansoni biogenic amine receptor 0.0164 0.0177 0.0202
Echinococcus multilocularis survival motor neuron protein 1 0.0271 0.0303 0.0374
Schistosoma mansoni zinc finger protein 0.0026 0.0013 0.0014
Brugia malayi beta-lactamase family protein 0.0031 0.0019 0.0019
Schistosoma mansoni kinase 0.073 0.0847 0.0969
Mycobacterium ulcerans hypothetical protein 0.0451 0.0517 0.0654
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0164 0.0177 0.018
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0002 0.0002
Echinococcus granulosus nuclear receptor nhr 48 0.0046 0.0037 0.0058
Trypanosoma brucei unspecified product 0.0023 0.0009 0.0044
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0037 0.0026 0.0121
Echinococcus granulosus microtubule associated protein 2 0.2455 0.2893 0.4576
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0166 0.0179 0.0202
Trypanosoma cruzi ISWI complex protein 0.0026 0.0013 0.0064
Schistosoma mansoni neuropeptide receptor 0.0164 0.0177 0.0202
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0164 0.0177 0.0202
Echinococcus granulosus neuropeptide Y receptor 0.0164 0.0177 0.0279
Echinococcus multilocularis ras GTP exchange factor 0.0023 0.0009 0.0011
Plasmodium falciparum replication factor C subunit 1, putative 0.0032 0.002 0.0127
Plasmodium vivax hypothetical protein, conserved 0.064 0.0741 0.5641
Brugia malayi sulfakinin receptor protein 0.0164 0.0177 0.0177
Mycobacterium leprae Probable polyketide synthase Pks1 0.4727 0.5588 0.7093
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Echinococcus granulosus integrin alpha ps 0.0106 0.0108 0.0171
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0098 0.0098 0.011
Echinococcus granulosus lysine specific demethylase 5A 0.003 0.0017 0.0026
Echinococcus granulosus DNA topoisomerase 1 0.0171 0.0185 0.0291
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0022 0.011
Schistosoma mansoni hypothetical protein 0.0164 0.0177 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0027 0.0014 0.0016
Echinococcus granulosus cpg binding protein 0.0024 0.0011 0.0017
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.4727 0.5588 0.7093
Trypanosoma cruzi Nicastrin, putative 0.0021 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Leishmania major GTP-binding protein, putative 0.0027 0.0014 0.0071
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0197 0.0215 0.1623
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0024 0.0011 0.0059
Echinococcus multilocularis expressed conserved protein 0.0026 0.0013 0.0016
Echinococcus granulosus tar DNA binding protein 0.0288 0.0323 0.051
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.001
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0024 0.0011 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0035 0.0035
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0054 0.0066
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0062 0.0055 0.007
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0029
Brugia malayi conserved hypotetical protein 0.0046 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Leishmania major hypothetical protein, conserved 0.0026 0.0013 0.0064
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0037 0.0026 0.0174
Mycobacterium ulcerans DNA polymerase IV 0.0033 0.0022 0.0025
Loa Loa (eye worm) NHE-3 0.0038 0.0027 0.003
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0074 0.0069 0.0085
Loa Loa (eye worm) hypothetical protein 0.1102 0.1289 0.1455
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Schistosoma mansoni cpg binding protein 0.0024 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0277 0.0311 0.1839
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0073 0.0069 0.0068
Entamoeba histolytica hypothetical protein 0.0021 0.0007 0.002
Echinococcus granulosus integrin alpha 3 0.0182 0.0198 0.0312
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0018 0.0003 0.0002
Mycobacterium tuberculosis Conserved protein 0.0031 0.0019 0.0024
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0035 0.0024 0.0039
Echinococcus granulosus poly (ADP ribose) polymerase 0.0064 0.0058 0.0091
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.1114 0.1304 0.7777
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.1377 0.1615 0.1822
Brugia malayi WGR domain containing protein 0.0293 0.0329 0.0329
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0277 0.0311 0.1846
Loa Loa (eye worm) hypothetical protein 0.0379 0.0431 0.0486
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0277 0.0311 0.0395
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0023 0.0009 0.0011
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0023 0.0009 0.0014
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0197 0.0215 0.1276
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0018 0.0003 0.0004
Loa Loa (eye worm) glutaminase 0.1365 0.1601 0.1806
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0052 0.0043 0.0068
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Giardia lamblia Replication factor C, subunit 1 0.0032 0.002 0.01
Brugia malayi G-protein coupled receptor 0.0164 0.0177 0.0177
Echinococcus multilocularis Nicastrin 0.0056 0.0049 0.006
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0022 0.0008 0.0044
Trichomonas vaginalis DNA polymerase eta, putative 0.0033 0.0022 0.0125
Loa Loa (eye worm) hypothetical protein 0.0941 0.1098 0.1239
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0132 0.0139 0.0158
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0031 0.0019 0.0024
Trypanosoma cruzi hexose transporter, putative 0.0025 0.0011 0.0057
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0277 0.0311 0.0311
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0036 0.0041
Mycobacterium ulcerans acyl carrier protein 0.0451 0.0517 0.0654
Onchocerca volvulus Pyruvate kinase homolog 0.0029 0.0017 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Echinococcus granulosus tm gpcr rhodopsin 0.0764 0.0888 0.1404
Schistosoma mansoni thyroid hormone receptor 0.0098 0.0098 0.0112
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0048 0.0039 0.0048
Echinococcus multilocularis integrin beta 2 0.0464 0.0532 0.0657
Mycobacterium tuberculosis Polyketide synthase Pks2 0.4328 0.5115 0.6493
Entamoeba histolytica Ran family GTPase 0.0027 0.0014 0.0063
Echinococcus multilocularis fmrfamide receptor 0.0164 0.0177 0.0218
Leishmania major phosphopantetheinyl transferase-like protein 0.0037 0.0026 0.0144
Brugia malayi Dopamine receptor protein 1 0.0164 0.0177 0.0177
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0052 0.0043 0.0053
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0002 0.0002
Echinococcus granulosus methyl CpG binding domain protein 2 0.0029 0.0016 0.0025
Schistosoma mansoni hypothetical protein 0.0732 0.085 0.0972
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0013 0.0015
Schistosoma mansoni methyltransferase-related 0.1345 0.1577 0.1804
Leishmania major glucose transporter, lmgt3 0.0025 0.0011 0.0057
Echinococcus multilocularis Niemann Pick C1 protein 0.0189 0.0206 0.0254
Trichomonas vaginalis glucose transporter, putative 0.0025 0.0011 0.0065
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.1085 0.1269 0.9679
Onchocerca volvulus 0.0164 0.0177 0.018
Schistosoma mansoni DNA ligase IV 0.0032 0.002 0.0022
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0293 0.0329 0.0407
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Brugia malayi Pyruvate kinase, M2 isozyme 0.0029 0.0017 0.0016
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0451 0.0517 0.0638
Leishmania major DNA topoisomerase type IB small subunit 0.0043 0.0033 0.0185
Schistosoma mansoni hypothetical protein 0.0436 0.0499 0.057
Loa Loa (eye worm) CXXC zinc finger family protein 0.002 0.0006 0.0006
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0037 0.0033
Loa Loa (eye worm) hypothetical protein 0.0086 0.0084 0.0095
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0024 0.004
Entamoeba histolytica pyruvate kinase, putative 0.002 0.0006 0.0017
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0037
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Echinococcus multilocularis Glycoside hydrolase, family 27 0.009 0.0088 0.0109
Schistosoma mansoni coup transcription factor 0.0098 0.0098 0.0112
Echinococcus granulosus sodium:hydrogen exchanger 0.0038 0.0027 0.0042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0164 0.0177 0.0202
Schistosoma mansoni tyrosine kinase 0.0069 0.0064 0.0073
Toxoplasma gondii acyl carrier protein ACP 0.0451 0.0517 0.0921
Giardia lamblia DINP protein human, muc B family 0.0033 0.0022 0.011
Echinococcus granulosus adam 0.0047 0.0038 0.0059
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0069 0.0064 0.0111
Brugia malayi Bromodomain containing protein 0.0131 0.0138 0.0138
Brugia malayi DIX domain containing protein 0.0032 0.002 0.002
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0277 0.0311 0.0395
Brugia malayi G-protein coupled receptor 0.0164 0.0177 0.0177
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.014 0.0148 0.0262
Leishmania major hypothetical protein, conserved 0.0033 0.0021 0.0112
Trypanosoma brucei Presenilin enhancer-2 subunit of gamma secretase, putative 0.0033 0.0021 0.0112
Toxoplasma gondii type I fatty acid synthase, putative 0.4729 0.559 1
Toxoplasma gondii type I fatty acid synthase 0.0685 0.0794 0.1418
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0277 0.0311 0.0395
Echinococcus multilocularis smad 0.0031 0.0018 0.0022
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Loa Loa (eye worm) hypothetical protein 0.0685 0.0794 0.0896
Loa Loa (eye worm) pyruvate kinase 0.0029 0.0017 0.0018
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0037 0.0058
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.2539 0.2992 0.3798
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0037
Echinococcus multilocularis muscleblind protein 0.0254 0.0283 0.035
Onchocerca volvulus Tankyrase homolog 0.003 0.0018 0.0014
Mycobacterium ulcerans polyketide synthase 0.445 0.5259 0.6675
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0094 0.0094 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0098 0.0098 0.0112
Echinococcus multilocularis geminin 0.0732 0.085 0.105
Brugia malayi ORL1-like opioid receptor 0.0164 0.0177 0.0177
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0098 0.0098 0.0121
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0038 0.0027 0.0023
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0022 0.0024
Trichomonas vaginalis esterase, putative 0.0031 0.0019 0.0111
Loa Loa (eye worm) hypothetical protein 0.0085 0.0082 0.0093
Brugia malayi EGF-like domain containing protein 0.002 0.0006 0.0006
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.2258 0.266 0.4757
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0277 0.0311 0.1846
Onchocerca volvulus 0.0277 0.0311 0.0321
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0277 0.0311 0.0395
Echinococcus granulosus AMP dependent ligase 0.0453 0.0519 0.082
Trichomonas vaginalis conserved hypothetical protein 0.1345 0.1577 0.9411
Leishmania major nuclear receptor binding factor-like protein 0.0277 0.0311 0.1846
Echinococcus granulosus regulator of G protein signaling 7 0.0032 0.002 0.0031
Trypanosoma cruzi hypothetical protein 0.0023 0.0009 0.0043
Brugia malayi neuropeptide F receptor 0.0164 0.0177 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0098 0.0098 0.0098
Echinococcus multilocularis neuropeptide FF receptor 2 0.0164 0.0177 0.0218
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0155 0.0155
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0026 0.0144
Schistosoma mansoni chromobox protein 0.0068 0.0063 0.0072
Echinococcus multilocularis protein jagged 2 0.002 0.0006 0.0007
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0026
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0035 0.0024 0.0129
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.002 0.0107
Mycobacterium ulcerans fatty acid synthase Fas 0.1403 0.1645 0.2087
Schistosoma mansoni hypothetical protein 0.0436 0.0499 0.057
Entamoeba histolytica acyl-CoA synthetase, putative 0.0045 0.0035 0.0189
Brugia malayi jmjC domain containing protein 0.0068 0.0063 0.0062
Echinococcus multilocularis fibrillin 1 0.0029 0.0017 0.002
Echinococcus granulosus survival motor neuron protein 1 0.0271 0.0303 0.0479
Loa Loa (eye worm) hypothetical protein 0.0325 0.0367 0.0414
Schistosoma mansoni dep domain containing protein 0.0032 0.002 0.0023
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0164 0.0177 0.0218
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0022 0.0008 0.0036
Leishmania major 4-coumarate:coa ligase-like protein 0.0045 0.0035 0.0196
Schistosoma mansoni transcription factor LCR-F1 0.0212 0.0234 0.0267
Leishmania major mitochondrial DNA polymerase beta 0.0264 0.0296 0.1755
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0035 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Entamoeba histolytica hypothetical protein 0.0023 0.0009 0.0035
Brugia malayi hypothetical protein 0.0027 0.0014 0.0014
Mycobacterium ulcerans beta-lactamase 0.0031 0.0019 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0022 0.0117
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.445 0.5259 0.6676
Loa Loa (eye worm) TK/ALK protein kinase 0.0281 0.0316 0.0356
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0277 0.0311 0.0395
Echinococcus granulosus adam 17 protease 0.017 0.0184 0.029
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0027 0.0014 0.0021
Schistosoma mansoni hypothetical protein 0.0436 0.0499 0.057
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0116 0.0119 0.07
Loa Loa (eye worm) hypothetical protein 0.0099 0.01 0.0112
Loa Loa (eye worm) hypothetical protein 0.3656 0.4317 0.4872
Loa Loa (eye worm) DNA topoisomerase I 0.0171 0.0185 0.0208
Echinococcus multilocularis AMP dependent ligase 0.0453 0.0519 0.0641
Schistosoma mansoni hypothetical protein 0.0056 0.0049 0.0055
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0032 0.002 0.0024
Plasmodium falciparum T-complex protein 1 subunit beta 0.0022 0.0008 0.0037
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0095 0.0095 0.0107
Loa Loa (eye worm) acyl carrier protein 0.2053 0.2417 0.2727
Echinococcus multilocularis protein patched 0.0081 0.0078 0.0096
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0024 0.001 0.0011
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0027 0.0014 0.0063
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0565 0.0652 0.0825
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.0043 0.0033 0.0185
Entamoeba histolytica hypothetical protein 0.0212 0.0234 0.1379
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0037 0.0045
Echinococcus multilocularis epidermal growth factor receptor 0.0072 0.0067 0.0083
Brugia malayi beta-lactamase 0.0031 0.0019 0.0019
Brugia malayi RasGEF domain containing protein 0.0023 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Brugia malayi hypothetical protein 0.0056 0.0049 0.0049
Entamoeba histolytica hypothetical protein 0.0212 0.0234 0.1379
Loa Loa (eye worm) hypothetical protein 0.0277 0.0311 0.0351
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0277 0.0311 0.1846
Toxoplasma gondii t-complex protein beta subunit 0.0022 0.0008 0.0011
Schistosoma mansoni hypothetical protein 0.0212 0.0234 0.0267
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0277 0.0311 0.0311
Plasmodium vivax acyl carrier protein, putative 0.0451 0.0517 0.3927
Echinococcus multilocularis snurportin 1 0.0389 0.0443 0.0547
Schistosoma mansoni glucose transport protein 0.008 0.0077 0.0088
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0033 0.0021 0.0027
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0024 0.001 0.001
Echinococcus multilocularis adam 17 protease 0.0155 0.0165 0.0204
Echinococcus multilocularis Nicastrin 0.0056 0.0049 0.006
Mycobacterium leprae Conserved hypothetical protein 0.0017 0.0002 0.0002
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0037 0.0026 0.0049
Mycobacterium tuberculosis Conserved hypothetical protein 0.0139 0.0147 0.0187
Echinococcus granulosus sodium:hydrogen exchanger 0.0038 0.0027 0.0042
Schistosoma mansoni bromodomain containing protein 0.0112 0.0114 0.0131
Plasmodium falciparum topoisomerase I 0.0171 0.0185 0.1387
Brugia malayi MH1 domain containing protein 0.0031 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0078 0.0075 0.0085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Mycobacterium tuberculosis Conserved hypothetical protein 0.0451 0.0517 0.0656
Trypanosoma brucei poly(adp-ribose) polymerase 0.0226 0.025 0.148
Giardia lamblia Sodium/hydrogen exchanger 3 0.0038 0.0027 0.0142
Echinococcus multilocularis importin subunit beta 1 0.0036 0.0025 0.0031
Trypanosoma brucei importin beta-1 subunit, putative 0.0036 0.0025 0.0139
Leishmania major quinone oxidoreductase, putative 0.0277 0.0311 0.1846
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0046 0.0037 0.0036
Echinococcus multilocularis gamma secretase subunit aph 1 0.0276 0.0309 0.0381
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0098 0.0098 0.0098
Giardia lamblia PHD finger protein 15 0.0021 0.0007 0.002
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0197 0.0215 0.1623
Echinococcus multilocularis neuropeptide Y receptor 0.0164 0.0177 0.0218
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0057 0.005 0.0057
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0166 0.0179 0.0283
Plasmodium falciparum acyl carrier protein 0.0451 0.0517 0.3927
Trypanosoma brucei THT1 - hexose transporter, putative 0.0025 0.0011 0.0057
Schistosoma mansoni hypothetical protein 0.0285 0.032 0.0365
Onchocerca volvulus 0.0164 0.0177 0.018
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0164 0.0177 0.0279
Echinococcus multilocularis muscleblind protein 1 0.0254 0.0283 0.035
Echinococcus multilocularis G protein coupled receptor 139 0.0164 0.0177 0.0218
Brugia malayi hypothetical protein 0.0212 0.0234 0.0234
Loa Loa (eye worm) neuropeptide F receptor 0.0164 0.0177 0.0199
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0026 0.0013 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Brugia malayi Heterochromatin protein 1 0.0068 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Brugia malayi chromobox protein homolog 3 0.0038 0.0027 0.0027
Echinococcus granulosus MAM 0.0033 0.0022 0.0034
Echinococcus granulosus somatostatin receptor 0.0164 0.0177 0.0279
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0276 0.0309 0.0348
Trypanosoma cruzi hypothetical protein 0.0023 0.0009 0.0043
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0048 0.0039 0.0277
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0164 0.0177 0.0202
Echinococcus multilocularis g protein coupled receptor 0.0164 0.0177 0.0218
Brugia malayi GnHR receptor homolog 0.0164 0.0177 0.0177
Echinococcus multilocularis neuropeptide s receptor 0.0589 0.0681 0.0841
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0057 0.005 0.0079
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0045 0.0035 0.0042
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0195 0.0213 0.0244
Schistosoma mansoni protein kinase 0.3668 0.4331 0.4954
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0035 0.0024 0.0026
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0277 0.0311 0.0392
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0032 0.002 0.0023
Schistosoma mansoni DNA topoisomerase type I 0.0128 0.0134 0.0153
Brugia malayi TAR-binding protein 0.0288 0.0323 0.0323
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0164 0.0177 0.0202
Schistosoma mansoni protein kinase 0.0035 0.0024 0.0027
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.0069 0.012
Onchocerca volvulus 0.0164 0.0177 0.018
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0037 0.0026 0.0043
Onchocerca volvulus 0.0031 0.0019 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0164 0.0177 0.0199
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0069 0.0064 0.0378
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0074 0.0069 0.0079
Onchocerca volvulus 0.0046 0.0037 0.0033
Brugia malayi Methyltransferase-like protein 4 0.1345 0.1577 0.1577
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi hypothetical protein 0.004 0.003 0.003
Mycobacterium leprae Probable lipase LipE 0.0031 0.0019 0.0024
Echinococcus granulosus peregrin 0.0028 0.0015 0.0024
Echinococcus multilocularis sodium:hydrogen exchanger 0.0038 0.0027 0.0033
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.1403 0.1645 0.2088
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.7488 0.8861 1
Brugia malayi Sugar transporter family protein 0.008 0.0077 0.0077
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0016 0.0018
Echinococcus granulosus tankyrase 0.003 0.0018 0.0028
Brugia malayi AMP-binding enzyme family protein 0.4185 0.4945 0.4944
Trypanosoma cruzi PAB1-binding protein , putative 0.0327 0.037 0.2196
Schistosoma mansoni ap endonuclease 0.0048 0.0039 0.0045
Trichomonas vaginalis glutaminase, putative 0.1365 0.1601 0.9551
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0189 0.0206 0.1212
Brugia malayi WGR domain containing protein 0.0226 0.025 0.0249
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus multilocularis neuropeptides capa receptor 0.0164 0.0177 0.0218
Loa Loa (eye worm) hypothetical protein 0.0056 0.0049 0.0055
Brugia malayi Integrin alpha pat-2 precursor 0.0237 0.0263 0.0263
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0022 0.0008 0.001
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0073 0.0069 0.0078
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0562 0.0648 0.0731
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0046 0.0037 0.0045
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0164 0.0177 0.0218
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0036 0.0213
Echinococcus multilocularis protein kinase shaggy 0.0057 0.005 0.0061
Echinococcus granulosus epidermal growth factor receptor 0.0072 0.0067 0.0106
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0166 0.0179 0.0221
Trichomonas vaginalis ap endonuclease, putative 0.0048 0.0039 0.0232
Schistosoma mansoni smad 0.0031 0.0018 0.0021
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Loa Loa (eye worm) hypothetical protein 0.0222 0.0245 0.0276
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0037 0.0036
Toxoplasma gondii hypothetical protein 0.0043 0.0033 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0069 0.0064 0.0412
Echinococcus multilocularis serotonin receptor 0.0427 0.0488 0.0602
Schistosoma mansoni histamine h1 receptor 0.0164 0.0177 0.0202
Trichomonas vaginalis importin beta-1, putative 0.003 0.0017 0.0098
Schistosoma mansoni hypothetical protein 0.0389 0.0443 0.0506
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0026 0.0013 0.002
Schistosoma mansoni integrin beta subunit 0.0369 0.0419 0.0479
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0325 0.0367 0.0654
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0212 0.0234 0.0289
Echinococcus multilocularis sex peptide receptor 0.0164 0.0177 0.0218
Trichomonas vaginalis CAMK family protein kinase 0.0711 0.0825 0.4921
Loa Loa (eye worm) hypothetical protein 0.0186 0.0203 0.0229
Leishmania major protein kinase, putative 0.0035 0.0024 0.0129
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0027 0.0014 0.0081
Toxoplasma gondii hypothetical protein 0.004 0.003 0.005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0098 0.0098 0.0098
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.011 0.0112 0.0128
Schistosoma mansoni tyrosine kinase 0.0069 0.0064 0.0073
Echinococcus granulosus L aminoadipate semialdehyde 0.0132 0.0139 0.0219
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0436 0.0499 0.0788
Loa Loa (eye worm) hypothetical protein 0.0062 0.0056 0.0063
Plasmodium falciparum calcium-dependent protein kinase 3 0.0035 0.0024 0.0156
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Schistosoma mansoni protein kinase 0.3668 0.4331 0.4954
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0023 0.0009 0.001
Echinococcus granulosus fibrillin 2 0.002 0.0006 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0037 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0019 0.0103
Leishmania major DNA polymerase eta, putative 0.0033 0.0022 0.0117
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0164 0.0177 0.0202
Echinococcus multilocularis PHD finger protein rhinoceros 0.0021 0.0007 0.0008
Brugia malayi RasGEF domain containing protein 0.0023 0.0009 0.0009
Echinococcus granulosus hypothetical protein 0.0664 0.0769 0.1217
Onchocerca volvulus Pyruvate kinase homolog 0.0029 0.0017 0.0012
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0027 0.0023
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0039 0.0029 0.0032
Echinococcus granulosus fetal alzheimer antigen falz 0.0039 0.0029 0.0045
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0048 0.0039 0.0277
Schistosoma mansoni adenoreceptor 0.0164 0.0177 0.0202
Schistosoma mansoni microtubule-associated protein tau 0.2455 0.2893 0.331
Schistosoma mansoni alpha-1 adrenergic receptor 0.0164 0.0177 0.0202
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0204 0.0224 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Schistosoma mansoni growth hormone secretagogue receptor 0.0164 0.0177 0.0202
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0197 0.0215 0.1276
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0282 0.0316 0.0399
Schistosoma mansoni hypothetical protein 0.0078 0.0075 0.0085
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0023 0.0009 0.0014
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0024 0.0011 0.001
Echinococcus granulosus dro:myosuppressin receptor 0.0164 0.0177 0.0279
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.6658 0.7878 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) MH2 domain-containing protein 0.0451 0.0516 0.0582
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0277 0.0311 0.0395
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0002 0.0002
Brugia malayi N-terminal motif family protein 0.0652 0.0756 0.0755
Brugia malayi nuclear hormone receptor 0.0046 0.0037 0.0036
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0226 0.025 0.148
Schistosoma mansoni sodium/chloride dependent transporter 0.0074 0.007 0.008
Mycobacterium ulcerans thioesterase TesA 0.3721 0.4394 0.5577
Brugia malayi larval opioid receptor 0.0164 0.0177 0.0177
Schistosoma mansoni nuclear receptor nhr-48 0.0046 0.0037 0.0042
Echinococcus granulosus segment polarity protein dishevelled 0.0032 0.002 0.0031
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0022 0.0008 0.0036
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0022 0.0034
Schistosoma mansoni zinc finger protein 0.0046 0.0037 0.0042
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0019 0.0111
Leishmania major protein kinase, putative 0.0026 0.0013 0.0066
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0045 0.0035 0.0044
Mycobacterium ulcerans hypothetical protein 0.0031 0.0019 0.0022
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0029
Loa Loa (eye worm) DR-78 0.0046 0.0037 0.0041
Brugia malayi PHD-finger family protein 0.0021 0.0007 0.0006
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0277 0.0311 0.0392
Trypanosoma brucei glucose transporter 2A 0.0025 0.0011 0.0057
Schistosoma mansoni retinoic acid receptor RXR 0.0098 0.0098 0.0112
Schistosoma mansoni survival motor neuron protein 0.0055 0.0047 0.0054
Schistosoma mansoni hypothetical protein 0.0164 0.0177 0.0202
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0031 0.0018 0.0021
Entamoeba histolytica serine/threonine protein kinase, putative 0.1428 0.1676 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0125 0.013 0.0768
Schistosoma mansoni DNA topoisomerase type I 0.0128 0.0134 0.0153
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0451 0.0517 0.0656
Leishmania major pyruvate kinase 0.0029 0.0017 0.0088
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0022 0.0008 0.0009
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0024 0.0038
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.1121 0.1311 0.1662
Plasmodium vivax glycogen synthase kinase 3, putative 0.0057 0.005 0.0358
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0098 0.0098 0.0098
Brugia malayi Bromodomain containing protein 0.0028 0.0015 0.0015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0506 0.0582 0.0719
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Echinococcus multilocularis g protein coupled receptor 0.0164 0.0177 0.0218
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0264 0.0296 0.1755
Echinococcus multilocularis neuropeptides capa receptor 0.0164 0.0177 0.0218
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0098 0.0098 0.0121
Loa Loa (eye worm) MH1 domain-containing protein 0.0031 0.0018 0.002
Echinococcus granulosus Protein son of sevenless 0.0023 0.0009 0.0014
Trichomonas vaginalis inositol monophosphatase, putative 0.0069 0.0064 0.0378
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0039 0.0029 0.0035
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0277 0.0311 0.1839
Onchocerca volvulus 0.0164 0.0177 0.018
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0019 0.0122
Brugia malayi Probable isocitrate dehydrogenase 0.0024 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Entamoeba histolytica protein kinase, putative 0.0035 0.0024 0.0122
Brugia malayi nuclear hormone receptor 0.0098 0.0098 0.0098
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0048 0.0039 0.0224
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0023 0.0009 0.0043
Loa Loa (eye worm) TK/INSR protein kinase 0.0157 0.0168 0.0189
Brugia malayi Dopamine receptor protein 2 0.0164 0.0177 0.0177
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.008 0.0077 0.0095
Echinococcus multilocularis nicalin 0.0021 0.0007 0.0008
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0464 0.0532 0.0676
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Loa Loa (eye worm) RasGEF domain-containing protein 0.0023 0.0009 0.001
Schistosoma mansoni cpg binding protein 0.0024 0.0011 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0019 0.0111
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0026 0.0144
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0078 0.0075 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.1428 0.1676 0.1917
Loa Loa (eye worm) nuclear receptor NHR-67 0.0046 0.0037 0.0041
Echinococcus multilocularis neuropeptide Y receptor 0.0164 0.0177 0.0218
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0048 0.0039 0.0062
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.008 0.0077 0.0095
Trypanosoma cruzi pyruvate kinase 2, putative 0.0029 0.0017 0.0088
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0277 0.0311 0.0392
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Brugia malayi tailless protein 0.0046 0.0037 0.0036
Brugia malayi hypothetical protein 0.004 0.003 0.003
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0038 0.0027 0.0033
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0097 0.0097 0.012
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0451 0.0517 0.0537
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0073 0.0069 0.0108
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0128 0.0134 0.0787
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Brugia malayi Bromodomain containing protein 0.0068 0.0063 0.0063
Mycobacterium tuberculosis Hypothetical protein 0.1345 0.1577 0.2002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0204 0.0224 0.0282
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0054 0.0085
Echinococcus granulosus tm gpcr rhodopsin 0.0506 0.0582 0.092
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.0195 0.0213 0.024
Entamoeba histolytica acyl-coA synthetase, putative 0.0045 0.0035 0.0189
Brugia malayi Melibiase family protein 0.006 0.0053 0.0053
Echinococcus multilocularis GPCR, family 2 0.0436 0.0499 0.0616
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0063 0.0071
Schistosoma mansoni hypothetical protein 0.0164 0.0177 0.0202
Brugia malayi nuclear hormone receptor family member odr-7 0.0046 0.0037 0.0036
Brugia malayi Pre-SET motif family protein 0.0081 0.0078 0.0078
Schistosoma mansoni sodium/chloride dependent transporter 0.0062 0.0056 0.0064
Trichomonas vaginalis ras GTP exchange factor, putative 0.0023 0.0009 0.0051
Trypanosoma cruzi Aph-1 protein, putative 0.0107 0.0109 0.0641
Mycobacterium leprae conserved hypothetical protein 0.0031 0.0019 0.0024
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0453 0.0519 0.0659
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0098 0.0098 0.011
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0164 0.0177 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Schistosoma mansoni dishevelled 0.0032 0.002 0.0023
Brugia malayi Probable isocitrate dehydrogenase 0.0024 0.001 0.001
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0685 0.0794 0.1008
Schistosoma mansoni tyrosine kinase 0.0157 0.0168 0.0191
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0069 0.0064 0.0363
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0125 0.013 0.0768
Onchocerca volvulus 0.0031 0.0019 0.0015
Brugia malayi ecdysteroid receptor 0.0444 0.0509 0.0509
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0453 0.0519 0.0659
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0192 0.0209 0.0239
Echinococcus granulosus poly (ADP ribose) polymerase 0.0064 0.0058 0.0091
Loa Loa (eye worm) transcription factor SMAD2 0.0451 0.0516 0.0582
Onchocerca volvulus 0.0277 0.0311 0.0321
Plasmodium falciparum pyruvate kinase 0.0029 0.0017 0.0102
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0024 0.0011 0.0012
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0019 0.0004 0.0015
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0173 0.0213
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0107
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0037 0.0058
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0282 0.0316 0.2393
Schistosoma mansoni topbp1 0.0032 0.002 0.0022
Brugia malayi Serotonin receptor 0.0164 0.0177 0.0177
Echinococcus multilocularis tumor protein p63 0.0261 0.0292 0.036
Onchocerca volvulus 0.0164 0.0177 0.018
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.1121 0.1311 1
Brugia malayi T-complex protein 1, beta subunit 0.0022 0.0008 0.0008
Echinococcus multilocularis nuclear receptor nhr 48 0.0046 0.0037 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.1085 0.1269 0.1611
Echinococcus granulosus 7TM GPCR rhodopsin 0.0164 0.0177 0.0279
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0019 0.0024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0043 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0023 0.0026
Mycobacterium leprae Probable oxidireductase 0.0277 0.0311 0.0395
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Echinococcus multilocularis lysine specific demethylase 5A 0.0025 0.0012 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0098 0.0098 0.0121
Echinococcus multilocularis sodium:hydrogen exchanger 0.0038 0.0027 0.0033
Echinococcus granulosus g protein coupled receptor 0.0164 0.0177 0.0279
Brugia malayi Cytochrome P450 family protein 0.0017 0.0002 0.0002
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0106 0.0107 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Echinococcus multilocularis serotonin receptor 0.0427 0.0488 0.0602
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0052 0.0043 0.0048
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0037 0.0026 0.0174
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0005 0.0004
Mycobacterium ulcerans hypothetical protein 0.0139 0.0147 0.0184
Echinococcus granulosus biogenic amine 5HT receptor 0.5347 0.6323 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0277 0.0311 0.0392
Echinococcus granulosus smad 0.0031 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0277 0.0311 0.0351
Plasmodium falciparum calcium-dependent protein kinase 1 0.0035 0.0024 0.0156
Loa Loa (eye worm) hypothetical protein 0.0245 0.0273 0.0308
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0164 0.0177 0.0202
Toxoplasma gondii isocitrate dehydrogenase 0.0197 0.0215 0.0382
Echinococcus multilocularis chromobox protein 1 0.0068 0.0063 0.0077
Loa Loa (eye worm) bromodomain containing protein 0.0033 0.0022 0.0024
Onchocerca volvulus 0.0639 0.074 0.0772
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0038 0.0027 0.0042
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Mycobacterium tuberculosis Conserved protein 0.1345 0.1577 0.2002
Loa Loa (eye worm) hypothetical protein 0.0051 0.0042 0.0048
Onchocerca volvulus 0.0033 0.0022 0.0017
Brugia malayi Cam kinase protein 1 0.0035 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0012
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0032 0.002 0.0016
Brugia malayi G protein-coupled receptor 0.0164 0.0177 0.0177
Brugia malayi Dopamine receptor 0.0164 0.0177 0.0177
Echinococcus multilocularis orexin receptor type 2 0.0164 0.0177 0.0218
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0164 0.0177 0.0202
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0035 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0024 0.0026
Brugia malayi Nuclear hormone receptor-like 1 0.0098 0.0098 0.0098
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0007
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0023 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0464 0.0532 0.0673
Plasmodium vivax SET domain protein, putative 0.0081 0.0078 0.0572
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0046 0.0037 0.0041
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0037
Schistosoma mansoni steroid hormone receptor ad4bp 0.0098 0.0098 0.0112
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0098 0.0098 0.0154
Giardia lamblia Tenascin-37 0.002 0.0006 0.0016
Trypanosoma brucei THT1 - hexose transporter, putative 0.0025 0.0011 0.0057
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0277 0.0311 0.0392
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Mycobacterium ulcerans Type I modular polyketide synthase 0.445 0.5259 0.6675
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0024 0.001 0.0016
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.0173 0.0173
Brugia malayi hypothetical protein 0.0056 0.0049 0.0049
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.445 0.5259 0.6675
Onchocerca volvulus 0.0032 0.002 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Trypanosoma cruzi pyruvate kinase 2, putative 0.0029 0.0017 0.0088
Schistosoma mansoni opsin-like receptor 0.0164 0.0177 0.0202
Mycobacterium ulcerans acyl carrier protein 0.0451 0.0517 0.0654
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0197 0.0215 0.1276
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.2937 0.3465 0.4399
Schistosoma mansoni integrin alpha-ps 0.0106 0.0108 0.0123
Echinococcus multilocularis NADH dehydrogenase 0.0451 0.0517 0.0638
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.005 0.0295
Brugia malayi hypothetical protein 0.0032 0.002 0.002
Brugia malayi AMP-binding enzyme family protein 0.1375 0.1612 0.1612
Onchocerca volvulus 0.0093 0.0092 0.0092
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0019 0.0111
Echinococcus granulosus inositol monophosphatase 1 0.0069 0.0064 0.0101
Brugia malayi putative neuropeptide receptor NPR1 0.0164 0.0177 0.0177
Entamoeba histolytica tartrate dehydrogenase, putative 0.0024 0.001 0.0043
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0164 0.0177 0.0177
Echinococcus multilocularis tankyrase 0.003 0.0018 0.0022
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0164 0.0177 0.0279
Trichomonas vaginalis DNA helicase recq, putative 0.0017 0.0002 0.001
Leishmania major DNA repair protein, putative 0.002 0.0005 0.0019
Brugia malayi Tnks protein 0.003 0.0018 0.0018
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1377 0.1615 0.1822
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Schistosoma mansoni neuropeptide receptor 0.0164 0.0177 0.0202
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0197 0.0215 0.0273
Loa Loa (eye worm) isocitrate dehydrogenase 0.0197 0.0215 0.0243
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0436 0.0499 0.0616
Schistosoma mansoni neuropeptide receptor 0.0164 0.0177 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0013 0.0015
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0453 0.0519 0.0656
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0098 0.0098 0.0121
Echinococcus granulosus pyruvate kinase 0.0029 0.0017 0.0026
Echinococcus multilocularis 0.0017 0.0002 0.0002
Schistosoma mansoni DNA topoisomerase type I 0.0171 0.0185 0.0211
Loa Loa (eye worm) hypothetical protein 0.0029 0.0017 0.0018
Entamoeba histolytica hypothetical protein 0.003 0.0018 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0009 0.0044
Schistosoma mansoni lysyl-tRNA synthetase 0.0018 0.0003 0.0003
Echinococcus multilocularis sodium and chloride dependent glycine 0.0062 0.0056 0.0069
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0024 0.001 0.0058
Brugia malayi hypothetical protein 0.0095 0.0095 0.0094
Loa Loa (eye worm) TAR-binding protein 0.0288 0.0323 0.0364
Plasmodium falciparum ataxin-2 like protein, putative 0.0327 0.037 0.2801
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0226 0.025 0.148
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0024 0.0011 0.0013
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.1373 0.161 0.2044
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0008 0.0009
Mycobacterium leprae Polyketide synthase Pks13 0.6658 0.7878 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus granulosus neuropeptide receptor A26 0.0589 0.0681 0.1076
Echinococcus multilocularis adam 0.0047 0.0038 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0002 0.0002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0081 0.0078 0.0096
Schistosoma mansoni neuropeptide F-like receptor 0.0164 0.0177 0.0202
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.1343 0.1575 0.1801
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0032 0.002 0.0023
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.1121 0.1311 0.7821
Entamoeba histolytica protein kinase, putative 0.0057 0.005 0.028
Schistosoma mansoni biogenic amine (5HT) receptor 0.5347 0.6323 0.7232
Loa Loa (eye worm) pyruvate kinase 0.0029 0.0017 0.0018
Echinococcus multilocularis tar DNA binding protein 0.0288 0.0323 0.0399
Schistosoma mansoni unc-13 (munc13) 0.0024 0.001 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0023 0.0009 0.001
Leishmania major glucose transporter, lmgt2 0.0025 0.0011 0.0057
Echinococcus granulosus poly (ADP ribose) polymerase 0.0064 0.0058 0.0091
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0045 0.0035 0.0042
Echinococcus multilocularis segment polarity protein dishevelled 0.0032 0.002 0.0024
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0064 0.037
Schistosoma mansoni sodium/hydrogen exchanger 0.0038 0.0027 0.0031
Echinococcus multilocularis neuropeptide receptor 0.0164 0.0177 0.0218
Brugia malayi isocitrate dehydrogenase 0.0197 0.0215 0.0215
Schistosoma mansoni tyrosine kinase 0.0072 0.0067 0.0077
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0036 0.0213
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.002 0.0115
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0053
Brugia malayi Smad1 0.0031 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus granulosus General substrate transporter 0.0069 0.0064 0.01
Schistosoma mansoni pyruvate kinase 0.0029 0.0017 0.0019
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0046 0.0037 0.0042
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.005 0.028
Brugia malayi Presenilin spe-4 0.004 0.003 0.003
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.1806 0.2123 0.2695
Trypanosoma cruzi oxidoreductase, putative 0.0277 0.0311 0.1846
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.003
Schistosoma mansoni tyrosine kinase 0.0069 0.0064 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0024 0.0137
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.1085 0.1269 0.2268
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Echinococcus granulosus neuropeptides capa receptor 0.0164 0.0177 0.0279
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0164 0.0177 0.0279
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0293 0.0329 0.195
Brugia malayi RNA binding protein 0.0288 0.0323 0.0323
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0022 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0065
Giardia lamblia Tenascin-X 0.002 0.0006 0.0016
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0047 0.0047
Echinococcus multilocularis regulator of G protein signaling 7 0.0032 0.002 0.0024
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0277 0.0311 0.0384
Mycobacterium tuberculosis Probable thioesterase TesA 0.3721 0.4394 0.5578
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0022 0.0117
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0081 0.0078 0.0088
Mycobacterium ulcerans oxidoreductase FadB5 0.0277 0.0311 0.0392
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0157 0.0168 0.0265
Brugia malayi Niemann-Pick C1 protein precursor 0.0189 0.0206 0.0206
Trypanosoma brucei PAB1-binding protein , putative 0.0327 0.037 0.2196
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0077 0.0073 0.0082
Schistosoma mansoni alpha-glucosidase 0.0139 0.0146 0.0167
Mycobacterium ulcerans aldehyde dehydrogenase 0.0204 0.0224 0.0282
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0271 0.0304 0.0385
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0098 0.0098 0.0112
Schistosoma mansoni nuclear hormone receptor 0.0098 0.0098 0.0112
Leishmania major DNA topoisomerase IB, large subunit 0.0128 0.0134 0.0787
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0277 0.0311 0.1846
Plasmodium falciparum phd finger protein, putative 0.0021 0.0007 0.0026
Echinococcus granulosus chromobox protein 1 0.0068 0.0063 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.011 0.0112 0.0128
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0379 0.0431 0.0493
Echinococcus granulosus poly ADP ribose polymerase 1 0.0293 0.0329 0.0521
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.009 0.0088 0.0109
Brugia malayi nuclear receptor RXR 0.0046 0.0037 0.0036
Schistosoma mansoni tankyrase 0.003 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Mycobacterium ulcerans polyketide synthase 0.4727 0.5588 0.7093
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Giardia lamblia Tenascin-like 0.002 0.0006 0.0016
Entamoeba histolytica zinc finger protein, putative 0.003 0.0018 0.0089
Schistosoma mansoni ap endonuclease 0.0048 0.0039 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Brugia malayi CHE-14 protein 0.0081 0.0078 0.0078
Leishmania major hypothetical protein, conserved 0.0327 0.037 0.2196
Entamoeba histolytica hypothetical protein 0.003 0.0017 0.0082
Loa Loa (eye worm) pyruvate kinase-PB 0.002 0.0006 0.0007
Schistosoma mansoni aldehyde dehydrogenase 0.0204 0.0224 0.0256
Echinococcus granulosus segment polarity protein dishevelled 0.0032 0.002 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0157 0.0168 0.0207
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0451 0.0517 0.3076
Trichomonas vaginalis CAMK family protein kinase 0.0711 0.0825 0.4921
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Leishmania major oxidoreductase-like protein 0.0277 0.0311 0.1846
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.064 0.0741 0.5641
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi hypothetical protein 0.0052 0.0043 0.0043
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0037 0.0026 0.0031
Plasmodium vivax pyruvate kinase, putative 0.0029 0.0017 0.0102
Onchocerca volvulus 0.0045 0.0035 0.0031
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0277 0.0311 0.0395
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0078 0.0089
Giardia lamblia TCP-1 chaperonin subunit beta 0.0022 0.0008 0.0029
Toxoplasma gondii lysine-tRNA ligase 0.0018 0.0003 0.0002
Schistosoma mansoni glucose transport protein 0.008 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus GTP binding nuclear protein Ran 0.0027 0.0014 0.0021
Echinococcus granulosus insulin receptor 0.0157 0.0168 0.0265
Trypanosoma brucei importin beta-1 subunit, putative 0.0036 0.0025 0.0139
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0451 0.0517 0.0517
Onchocerca volvulus Protein ultraspiracle homolog 0.0098 0.0098 0.0097
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0031 0.0019 0.0019
Mycobacterium leprae conserved hypothetical protein 0.0451 0.0517 0.0656
Schistosoma mansoni hypothetical protein 0.0941 0.1098 0.1256
Echinococcus multilocularis inositol monophosphatase 1 0.0069 0.0064 0.0079
Brugia malayi lysyl-tRNA synthetase 0.0018 0.0003 0.0003
Mycobacterium ulcerans oxidoreductase 0.0277 0.0311 0.0392
Onchocerca volvulus 0.0164 0.0177 0.018
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0147 0.0156 0.0246
Echinococcus multilocularis presenilin 0.0116 0.0119 0.0147
Echinococcus granulosus geminin 0.0732 0.085 0.1344
Echinococcus granulosus Smad4 0.0031 0.0018 0.0029
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.008 0.0077 0.0122
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.008 0.0077 0.0095
Schistosoma mansoni glutaminase 0.1365 0.1601 0.1831
Trypanosoma brucei DNA repair protein, putative 0.002 0.0005 0.0019
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0098 0.0098 0.0121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.009 0.0088 0.0139
Entamoeba histolytica hypothetical protein 0.003 0.0018 0.0089
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0033 0.0021 0.0025
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0277 0.0311 0.0392
Toxoplasma gondii protein kinase, putative 0.0237 0.0263 0.0468
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0098 0.0098 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0031 0.0018 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0098 0.0098 0.011
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0226 0.025 0.0285
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Toxoplasma gondii pyruvate kinase PyK1 0.0029 0.0017 0.0026
Echinococcus multilocularis presenilin enhancer 2 0.0108 0.0111 0.0136
Schistosoma mansoni [ACP] S-malonyltransferase 0.0282 0.0316 0.0361
Echinococcus granulosus ecdysone induced protein 78C 0.0098 0.0098 0.0154
Toxoplasma gondii hypothetical protein 0.0032 0.002 0.0032
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.006 0.0053 0.006
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0029
Trypanosoma cruzi hexose transporter 0.0025 0.0011 0.0057
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Onchocerca volvulus 0.0164 0.0177 0.018
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0048 0.0039 0.0216
Plasmodium vivax acyl-CoA synthetase, putative 0.0033 0.0021 0.0139
Mycobacterium tuberculosis Probable oxidoreductase 0.0277 0.0311 0.0395
Loa Loa (eye worm) T-complex protein 1 0.0022 0.0008 0.0009
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.0282 0.0316 0.2393
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0032 0.002 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Onchocerca volvulus 0.0164 0.0177 0.018
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0098 0.0098 0.0098
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0038 0.0027 0.0042
Trypanosoma brucei RNA helicase, putative 0.0107 0.0109 0.0641
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0036 0.0061
Echinococcus multilocularis regulator of G protein signaling 7 0.0032 0.002 0.0024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0037 0.0045
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0046 0.0037 0.0058
Echinococcus multilocularis lysyl tRNA synthetase 0.0018 0.0003 0.0004
Echinococcus multilocularis 0.002 0.0006 0.0007
Brugia malayi Protein kinase domain containing protein 0.0087 0.0085 0.0085
Echinococcus multilocularis pyruvate kinase 0.0023 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Echinococcus granulosus allatostatin A receptor 0.0164 0.0177 0.0279
Entamoeba histolytica hypothetical protein 0.003 0.0018 0.0089
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.0436 0.0499 0.0562
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0022 0.0026
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0046 0.0037 0.0042
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0162 0.0174 0.0196
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0166 0.0179 0.0221
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0164 0.0177 0.0202
Brugia malayi hypothetical protein 0.0211 0.0232 0.0232
Trypanosoma cruzi DNA repair protein, putative 0.002 0.0005 0.0019
Trichomonas vaginalis pyruvate kinase, putative 0.0029 0.0017 0.0096
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Trypanosoma cruzi oxidoreductase, putative 0.0277 0.0311 0.1846
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.0116 0.0119 0.07
Loa Loa (eye worm) hypothetical protein 0.0254 0.0283 0.0319
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0197 0.0215 0.0266
Echinococcus granulosus neuropeptides capa receptor 0.0164 0.0177 0.0279
Mycobacterium ulcerans polyketide synthase MbtD 0.1373 0.161 0.2042
Schistosoma mansoni patched 1 0.0081 0.0078 0.0089
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0024 0.0027
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.445 0.5259 0.5259
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.152 0.1784 0.2265
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Echinococcus granulosus calcium dependent protein kinase 0.0023 0.0009 0.0014
Loa Loa (eye worm) RNA binding protein 0.0288 0.0323 0.0364
Loa Loa (eye worm) gamma-secretase subunit pen-2 0.0108 0.0111 0.0125
Echinococcus granulosus tm gpcr rhodopsin 0.0164 0.0177 0.0279
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Brugia malayi hypothetical protein 0.0327 0.037 0.0369
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0022 0.0008 0.0029
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0045 0.0035 0.0044
Leishmania major acyl carrier protein, putative 0.0451 0.0517 0.3076
Echinococcus granulosus smoothened 0.0227 0.0251 0.0396
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.1121 0.1311 0.7821
Schistosoma mansoni inositol monophosphatase 0.0069 0.0064 0.0073
Echinococcus granulosus neuropeptide FF receptor 2 0.0164 0.0177 0.0279
Schistosoma mansoni ras GTP exchange factor 0.0023 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0081 0.0078 0.0088
Trichomonas vaginalis replication factor C large subunit, putative 0.0032 0.002 0.0115
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0037 0.0042
Onchocerca volvulus 0.0098 0.0098 0.0097
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0035 0.0024 0.0156
Onchocerca volvulus 0.003 0.0018 0.0013
Giardia lamblia Methyltransferase like 2 0.1345 0.1577 0.941
Schistosoma mansoni hypothetical protein 0.0026 0.0013 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0271 0.0303 0.0341
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.684 0.8093 1
Trypanosoma brucei Nicastrin, putative 0.0021 0.0007 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.002 0.0107
Trichomonas vaginalis sugar transporter, putative 0.0025 0.0011 0.0065
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0277 0.0311 0.0491
Mycobacterium ulcerans DNA polymerase IV 0.0033 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi gamma-secretase subunit pen-2 0.0108 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0352 0.0399 0.045
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Brugia malayi RasGEF domain containing protein 0.0023 0.0009 0.0009
Leishmania major importin beta-1 subunit, putative 0.003 0.0017 0.009
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0048 0.0039 0.005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0037 0.0026 0.0144
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.001
Echinococcus granulosus integrin alpha ps 0.0051 0.0042 0.0067
Brugia malayi Bloom's syndrome protein homolog 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0008 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Onchocerca volvulus 0.0164 0.0177 0.018
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0007 0.0026
Onchocerca volvulus 0.0038 0.0027 0.0023
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0032 0.002 0.0073
Echinococcus multilocularis pyruvate kinase 0.0029 0.0017 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0009 0.0044
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0035 0.0024 0.0039
Toxoplasma gondii facilitative glucose transporter GT1 0.008 0.0077 0.0135
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.1121 0.1311 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0027 0.0014 0.0017
Schistosoma mansoni z-protein (S1r protein) 0.0032 0.002 0.0023
Onchocerca volvulus 0.002 0.0006 0.0001
Mycobacterium tuberculosis Probable hydrolase 0.0031 0.0019 0.0024
Echinococcus multilocularis somatostatin receptor 0.0164 0.0177 0.0218
Leishmania major hypothetical protein, conserved 0.002 0.0005 0.0019
Echinococcus granulosus son of sevenless 1 0.0023 0.0009 0.0014
Echinococcus multilocularis fmrfamide receptor 0.0164 0.0177 0.0218
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0007 0.0008
Echinococcus granulosus muscleblind protein 0.0254 0.0283 0.0448
Echinococcus granulosus poly adp ribose polymerase 2 0.0226 0.025 0.0394
Schistosoma mansoni lysyl-tRNA synthetase 0.0018 0.0003 0.0003
Loa Loa (eye worm) acetyltransferase 0.0146 0.0155 0.0175
Schistosoma mansoni hypothetical protein 0.0051 0.0042 0.0048
Echinococcus multilocularis sterol regulatory element binding protein 0.0081 0.0078 0.0096
Mycobacterium ulcerans Type I modular polyketide synthase 0.445 0.5259 0.6675
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0204 0.0224 0.1329
Brugia malayi EGF-like domain containing protein 0.002 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0002 0.0002
Trypanosoma brucei pyruvate kinase 1 0.0029 0.0017 0.0088
Brugia malayi Tachykinin-like peptides receptor 99D 0.0164 0.0177 0.0177
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0098 0.0098 0.0112
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0024 0.001 0.0016
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.445 0.5259 0.6676
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0057 0.005 0.0287
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0277 0.0311 0.0395
Schistosoma mansoni alcohol dehydrogenase 0.0277 0.0311 0.0355
Echinococcus granulosus TGF beta signal transducer SmadC 0.0031 0.0018 0.0029
Echinococcus multilocularis isocitrate dehydrogenase 0.0197 0.0215 0.0266
Trypanosoma cruzi hexose transporter, putative 0.0025 0.0011 0.0057
Loa Loa (eye worm) hypothetical protein 0.011 0.0112 0.0126
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0088 0.0101
Mycobacterium tuberculosis Probable esterase LipL 0.0031 0.0019 0.0024
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Echinococcus multilocularis biogenic amine (5HT) receptor 0.5347 0.6323 0.7812
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0032 0.002 0.0016
Mycobacterium ulcerans polyketide synthase MbtC 0.1121 0.1311 0.1662
Leishmania major hypothetical protein, conserved 0.1345 0.1577 0.941
Brugia malayi Phosphopantetheine attachment site family protein 0.0451 0.0517 0.0517
Echinococcus multilocularis neuropeptide receptor 0.0164 0.0177 0.0218
Schistosoma mansoni opsin-like receptor 0.0164 0.0177 0.0202
Echinococcus multilocularis fibrillin 2 0.002 0.0006 0.0007
Trichomonas vaginalis glucose transporter, putative 0.0025 0.0011 0.0065
Mycobacterium ulcerans quinone oxidoreductase 0.0277 0.0311 0.0392
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0002 0.0002
Echinococcus granulosus neuropeptide receptor 0.0164 0.0177 0.0279
Loa Loa (eye worm) hypothetical protein 0.0179 0.0195 0.022
Giardia lamblia High cysteine protein 0.002 0.0006 0.0016
Brugia malayi hypothetical protein 0.0052 0.0043 0.0043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0098 0.0098 0.0121
Toxoplasma gondii DNA topoisomerase I, putative 0.0171 0.0185 0.0327
Schistosoma mansoni smad1 5 8 and 0.0031 0.0018 0.0021
Brugia malayi Presenilin family protein 0.0116 0.0119 0.0119
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0048 0.0039 0.0224
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0045 0.0035 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Onchocerca volvulus 0.0464 0.0532 0.0554
Echinococcus multilocularis ecdysone induced protein 78C 0.0098 0.0098 0.0121
Echinococcus granulosus cGMP dependent protein kinase 0.0026 0.0013 0.002
Echinococcus multilocularis g-protein coupled receptor 0.0164 0.0177 0.0218
Brugia malayi MH2 domain containing protein 0.0031 0.0018 0.0018
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0128 0.0134 0.0787
Echinococcus granulosus regulator of G protein signaling 7 0.0032 0.002 0.0031
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0451 0.0517 0.0656
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0155 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0098 0.0098 0.0098
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0002 0.0002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0204 0.0224 0.0282
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0018 0.0003 0.0016
Mycobacterium ulcerans lipase LipD 0.0031 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0045 0.0035 0.0039
Brugia malayi Cytochrome P450 family protein 0.0017 0.0002 0.0002
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Echinococcus granulosus presenilin 0.0116 0.0119 0.0188
Echinococcus multilocularis peregrin 0.0028 0.0015 0.0019
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.0173 0.0273
Echinococcus granulosus chromobox protein 1 0.0068 0.0063 0.0099
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0098 0.0098 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Schistosoma mansoni smad1 5 8 and 0.0031 0.0018 0.0021
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.008 0.0077 0.0122
Onchocerca volvulus 0.0164 0.0177 0.018
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0038 0.0027 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0024 0.0134
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0132 0.0139 0.0138
Trichomonas vaginalis set domain proteins, putative 0.0639 0.074 0.4414
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.4727 0.5588 0.7093
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Trichomonas vaginalis Nicastrin precursor, putative 0.0056 0.0049 0.0288
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0197 0.0215 0.034
Trypanosoma cruzi ISWI complex protein 0.0026 0.0013 0.0064
Plasmodium falciparum hexose transporter 0.008 0.0077 0.0565
Brugia malayi Inositol-1 0.0069 0.0064 0.0064
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0028 0.0015 0.0024
Echinococcus granulosus sodium and chloride dependent glycine 0.0062 0.0056 0.0088
Chlamydia trachomatis pyruvate kinase 0.0029 0.0017 0.0102
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0074 0.0069 0.0109
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0019 0.0022
Schistosoma mansoni hypothetical protein 0.0436 0.0499 0.057
Mycobacterium ulcerans hypothetical protein 0.0045 0.0035 0.0042
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0264 0.0296 0.1755
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0451 0.0517 0.0583
Mycobacterium ulcerans glutaminase 0.1365 0.1601 0.203
Trichomonas vaginalis Importin beta-1 subunit, putative 0.003 0.0017 0.0098
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.0116 0.0119 0.0136
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.4727 0.5588 0.7093
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0002 0.0002
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0436 0.0499 0.0788
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.2897 0.3417 0.6111
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0685 0.0794 0.1008
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.006 0.0053 0.0312
Schistosoma mansoni tyrosine kinase 0.0072 0.0067 0.0077
Loa Loa (eye worm) hypothetical protein 0.0327 0.037 0.0417
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0164 0.0177 0.0218
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0464 0.0532 0.0673
Echinococcus granulosus dna polymerase kappa 0.0033 0.0022 0.0034
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.0024 0.001 0.0013
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.011 0.0112 0.0138
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0027 0.0014 0.0071
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0464 0.0532 0.0673
Mycobacterium ulcerans dehydrogenase 0.0277 0.0311 0.0392
Trypanosoma brucei oxidoreductase, putative 0.0277 0.0311 0.1846
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0037 0.0058
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0032 0.002 0.0022
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0057 0.005 0.0287
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0022 0.0027
Schistosoma mansoni gamma-secretase subunit aph-1 0.0276 0.0309 0.0353
Loa Loa (eye worm) hypothetical protein 0.0226 0.025 0.0281
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0035 0.0042
Leishmania major 4-coumarate:coa ligase-like protein 0.0045 0.0035 0.0196
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1428 0.1676 0.265
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0022 0.0008 0.0012
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0029 0.0016 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Brugia malayi serine/threonine-protein kinase plk-2 0.1428 0.1676 0.1676
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0027 0.0185
Loa Loa (eye worm) hypothetical protein 0.0282 0.0316 0.0357
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0277 0.0311 0.0395
Echinococcus multilocularis integrin alpha 3 0.0182 0.0198 0.0244
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0652 0.0756 0.0788
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0164 0.0177 0.0218
Mycobacterium ulcerans polyketide synthase Pks13 0.6658 0.7878 1
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Echinococcus multilocularis pyruvate kinase 0.0029 0.0017 0.002
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0024 0.001 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0464 0.0532 0.0673
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0164 0.0177 0.0202
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0048 0.0039 0.0044
Echinococcus multilocularis bloom syndrome protein 0.0017 0.0002 0.0002
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0164 0.0177 0.0202
Leishmania major glucose transporter/membrane transporter D2, putative 0.0025 0.0011 0.0057
Onchocerca volvulus 0.0033 0.0022 0.0017
Echinococcus multilocularis DNA topoisomerase 1 0.0171 0.0185 0.0228
Entamoeba histolytica hypothetical protein 0.0032 0.002 0.01
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0024 0.0011 0.0012
Trypanosoma cruzi FHA domain containing protein, putative 0.0032 0.002 0.0107
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0277 0.0311 0.0553
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0029 0.0017 0.0021
Toxoplasma gondii hypothetical protein 0.0033 0.0021 0.0034
Echinococcus multilocularis dnaJ subfamily B 0.0285 0.032 0.0395
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0017 0.0019
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0164 0.0177 0.0199
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0026 0.0013 0.0016
Brugia malayi glutaminase DH11.1 0.1365 0.1601 0.16
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0035 0.0035
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.0038 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0444 0.0509 0.0574
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0045 0.0035 0.0044
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0033 0.0022 0.0125
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0032 0.002 0.0025
Echinococcus multilocularis neuropeptide receptor A26 0.0589 0.0681 0.0841
Echinococcus granulosus expressed conserved protein 0.0177 0.0192 0.0304
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.1085 0.1269 0.1611
Trypanosoma cruzi PAB1-binding protein , putative 0.0327 0.037 0.2196
Trypanosoma cruzi polo-like protein kinase, putative 0.1428 0.1676 1
Trypanosoma brucei acyl transferase-like protein 0.0282 0.0316 0.1878
Echinococcus granulosus poly (ADP ribose) polymerase 0.0128 0.0133 0.021
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0078 0.0074 0.0117
Trypanosoma brucei unspecified product 0.0023 0.0009 0.0044
Toxoplasma gondii LsmAD domain-containing protein 0.0327 0.037 0.0658
Loa Loa (eye worm) glutaminase 2 0.1365 0.1601 0.1806
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0451 0.0517 0.0656
Entamoeba histolytica acyl-CoA synthetase, putative 0.0496 0.057 0.3386
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0024 0.0142
Echinococcus multilocularis L aminoadipate semialdehyde 0.0132 0.0139 0.0171
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0017 0.0019
Mycobacterium tuberculosis Probable lipase LipE 0.0031 0.0019 0.0024
Brugia malayi PHD-finger family protein 0.0047 0.0037 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0043 0.0043
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0024 0.001 0.0012
Mycobacterium ulcerans pyruvate kinase 0.0029 0.0017 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0069 0.0064 0.0079
Toxoplasma gondii quinone oxidoreductase, putative 0.0277 0.0311 0.0553
Brugia malayi beta-lactamase family protein 0.0031 0.0019 0.0019
Trichomonas vaginalis ap endonuclease, putative 0.0048 0.0039 0.0232
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0016 0.0018
Echinococcus granulosus ras GTP exchange factor 0.0023 0.0009 0.0014
Brugia malayi exodeoxyribonuclease III family protein 0.0048 0.0039 0.0039
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0027 0.0014 0.0015
Leishmania major glucose transporter, lmgt1 0.0025 0.0011 0.0057
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0212 0.0234 0.0369
Echinococcus multilocularis microtubule associated protein 2 0.2455 0.2893 0.3575
Loa Loa (eye worm) hypothetical protein 0.0264 0.0295 0.0333
Leishmania major zinc-binding dehydrogenase-like protein 0.0277 0.0311 0.1846
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.3668 0.4331 0.685
Brugia malayi gamma-secretase subunit aph-1 0.0276 0.0309 0.0308
Echinococcus multilocularis smoothened 0.0227 0.0251 0.0309
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0033 0.0022 0.0027
Mycobacterium ulcerans oxidoreductase 0.0277 0.0311 0.0392
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0277 0.0311 0.2311
Schistosoma mansoni inositol monophosphatase 0.0069 0.0064 0.0073
Loa Loa (eye worm) hypothetical protein 0.0045 0.0035 0.0039
Echinococcus granulosus Niemann Pick C1 protein 0.027 0.0302 0.0477
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0055 0.0062
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0057 0.005 0.0086
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.002 0.0115
Schistosoma mansoni glucose transport protein 0.008 0.0077 0.0088
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0685 0.0794 0.1008
Brugia malayi Protein kinase domain containing protein 0.0157 0.0168 0.0167
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Onchocerca volvulus 0.0023 0.0009 0.0004
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.7388 0.8742 1
Echinococcus granulosus acyl carrier protein mitochondrial 0.0451 0.0517 0.0817
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Brugia malayi follicle stimulating hormone receptor 0.0366 0.0416 0.0416
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0033 0.0022 0.0117
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0033 0.0021 0.0139
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.1121 0.1311 0.1311
Plasmodium vivax replication factor C subunit 1, putative 0.0032 0.002 0.0127
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0051
Echinococcus granulosus gamma secretase subunit aph 1 0.0276 0.0309 0.0488
Loa Loa (eye worm) hypothetical protein 0.0036 0.0025 0.0028
Loa Loa (eye worm) hypothetical protein 0.0379 0.0431 0.0486
Echinococcus granulosus jumonji domain containing protein 0.0029 0.0016 0.0025
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0024 0.001 0.001
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0052 0.0043 0.0049
Echinococcus granulosus zinc finger protein 0.0038 0.0027 0.0042
Brugia malayi Pre-SET motif family protein 0.0562 0.0648 0.0648
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0046 0.0037 0.0045
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0048 0.0039 0.0224
Echinococcus granulosus sodium and chloride dependent glycine 0.0062 0.0056 0.0088
Echinococcus multilocularis chromobox protein 1 0.0068 0.0063 0.0077
Loa Loa (eye worm) RasGEF domain-containing protein 0.0023 0.0009 0.001
Plasmodium falciparum mitogen-activated protein kinase 2 0.014 0.0148 0.1109
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Brugia malayi regulator of G-protein signaling egl-10 0.0032 0.002 0.002
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0043 0.0043
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0035 0.0024 0.0026
Echinococcus multilocularis dna polymerase kappa 0.0033 0.0022 0.0026
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.1121 0.1311 0.1479
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0037 0.0026 0.0031
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0277 0.0311 0.0395
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Brugia malayi G protein-coupled receptor F59B2.13 0.0164 0.0177 0.0177
Echinococcus granulosus nicalin 0.0021 0.0007 0.001
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0023 0.0009 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0027 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Giardia lamblia Prolyl-tRNA synthetase 0.0024 0.0011 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0002 0.0002
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.008 0.0077 0.0122
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.445 0.5259 0.6676
Treponema pallidum exodeoxyribonuclease (exoA) 0.0048 0.0039 0.0156
Giardia lamblia High cysteine protein 0.002 0.0006 0.0016
Echinococcus granulosus cGMP dependent protein kinase 1 0.0026 0.0013 0.002
Brugia malayi Presenilin spe-4 0.004 0.003 0.003
Schistosoma mansoni [ACP] S-malonyltransferase 0.0282 0.0316 0.0361
Echinococcus multilocularis integrin alpha ps 0.0106 0.0108 0.0133
Schistosoma mansoni jumonji domain containing protein 0.0054 0.0046 0.0052
Leishmania major hypothetical protein, conserved 0.0282 0.0316 0.1878
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0011
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0032 0.002 0.01
Schistosoma mansoni hypothetical protein 0.008 0.0077 0.0088
Brugia malayi AKH receptor 0.0164 0.0177 0.0177
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.0116 0.0119 0.07
Entamoeba histolytica hypothetical protein 0.0212 0.0234 0.1379
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0277 0.0311 0.0395
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.0043 0.0033 0.0185
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0164 0.0177 0.0177
Schistosoma mansoni alpha-glucosidase 0.0139 0.0146 0.0167
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0164 0.0177 0.0218
Echinococcus granulosus serotonin receptor 0.0164 0.0177 0.0279
Onchocerca volvulus 0.0031 0.0019 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0098 0.0098 0.011
Onchocerca volvulus 0.0164 0.0177 0.018
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0031 0.0019 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.0091 0.0104
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0037 0.0042
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0164 0.0177 0.0199
Onchocerca volvulus 0.0046 0.0037 0.0033
Trypanosoma cruzi Nicastrin, putative 0.0021 0.0007 0.0027
Onchocerca volvulus Neuropeptide F receptor homolog 0.0164 0.0177 0.018
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 0.9679
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0019 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Brugia malayi Steroid receptor seven-up type 2 0.0098 0.0098 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0166 0.0179 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0031 0.018
Plasmodium falciparum glycogen synthase kinase 3 0.0057 0.005 0.0358
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0764 0.0888 0.1097
Trypanosoma cruzi acyl transferase-like protein 0.0282 0.0316 0.1878
Echinococcus granulosus neuropeptide Y receptor 0.0164 0.0177 0.0279
Loa Loa (eye worm) fatty acid synthase 0.4406 0.5206 0.5875
Brugia malayi Protein kinase domain containing protein 0.0281 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus granulosus replication factor c subunit 1 0.0032 0.002 0.0031
Loa Loa (eye worm) melatonin receptor type 1A 0.0164 0.0177 0.0199
Giardia lamblia Pyruvate kinase 0.0029 0.0017 0.008
Echinococcus granulosus neuropeptide receptor 0.0164 0.0177 0.0279
Trichomonas vaginalis hypothetical protein 0.002 0.0006 0.0032
Plasmodium vivax importin-beta 2, putative 0.0036 0.0025 0.0168
Brugia malayi Alcohol dehydrogenase class III 0.0277 0.0311 0.0311
Schistosoma mansoni ran 0.0027 0.0014 0.0015
Plasmodium falciparum calcium-dependent protein kinase 5 0.0035 0.0024 0.0156
Toxoplasma gondii isocitrate dehydrogenase 0.0197 0.0215 0.0382
Schistosoma mansoni hypothetical protein 0.0107 0.0109 0.0125
Schistosoma mansoni hypothetical protein 0.0033 0.0022 0.0024
Schistosoma mansoni cellular tumor antigen P53 0.0038 0.0027 0.0031
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.002 0.0005 0.0019
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0035 0.0024 0.0156
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0277 0.0311 0.1852
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0024 0.001 0.0012
Echinococcus granulosus epidermal growth factor receptor 0.0072 0.0067 0.0106
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.005 0.0295
Loa Loa (eye worm) hypothetical protein 0.0189 0.0206 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0009 0.0044
Schistosoma mansoni hypothetical protein 0.0147 0.0156 0.0178
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0277 0.0311 0.0392
Echinococcus granulosus thyroid hormone receptor alpha 0.0046 0.0037 0.0058
Plasmodium falciparum ataxin-2 like protein, putative 0.0327 0.037 0.2801
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0002 0.0003
Brugia malayi hypothetical protein 0.0032 0.002 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Schistosoma mansoni hypothetical protein 0.0055 0.0047 0.0054
Loa Loa (eye worm) integrin beta-2 0.0626 0.0724 0.0817
Schistosoma mansoni aldehyde dehydrogenase 0.0204 0.0224 0.0256
Brugia malayi nuclear hormone receptor family member nhr-6 0.0046 0.0037 0.0036
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0098 0.0098 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0098 0.0098 0.0098
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.1121 0.1311 0.2343
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0018 0.0003 0.0002
Schistosoma mansoni Smad4 0.0031 0.0018 0.0021
Loa Loa (eye worm) nuclear hormone receptor 0.0046 0.0037 0.0041
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0024 0.0024
Mycobacterium ulcerans thioesterase 0.3721 0.4394 0.5577
Brugia malayi Melatonin receptor type 1A 0.0164 0.0177 0.0177
Leishmania major hypothetical protein, conserved 0.0031 0.0019 0.0103
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0164 0.0177 0.0218
Echinococcus granulosus tumor protein p63 0.0261 0.0292 0.0461
Giardia lamblia Kinase, CMGC GSK 0.0057 0.005 0.028
Plasmodium vivax calcium-dependent protein kinase, putative 0.0035 0.0024 0.0156
Schistosoma mansoni zinc binding dehydrogenase 0.0277 0.0311 0.0355
Brugia malayi Presenilin-like protein At2g29900 0.004 0.003 0.003
Loa Loa (eye worm) steroid hormone receptor 0.0098 0.0098 0.011
Loa Loa (eye worm) presenilin spe-4 0.004 0.003 0.0034
Entamoeba histolytica hypothetical protein 0.0064 0.0058 0.0325
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.002 0.0107
Brugia malayi Egg laying defective protein 4 0.0026 0.0013 0.0013
Plasmodium falciparum calcium-dependent protein kinase 2 0.0035 0.0024 0.0156
Loa Loa (eye worm) hypothetical protein 0.0062 0.0056 0.0063
Loa Loa (eye worm) RecQ helicase 0.0017 0.0002 0.0002
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0277 0.0311 0.0311
Mycobacterium ulcerans lipoprotein LpqF 0.0271 0.0304 0.0383
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0164 0.0177 0.0279
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0088 0.0101
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0064 0.037
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.014 0.0148 0.1109
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Echinococcus granulosus FTZ F1 alpha 0.0098 0.0098 0.0154
Brugia malayi hypothetical protein 0.0033 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.1121 0.1311 0.1499
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0098 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0036 0.0057
Brugia malayi Integrin beta pat-3 precursor 0.0626 0.0724 0.0724
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Brugia malayi DNA topoisomerase I 0.0171 0.0185 0.0184
Trichomonas vaginalis sugar transporter, putative 0.0025 0.0011 0.0065
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.3208 0.3786 0.4806
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0106 0.0107 0.0132
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.1403 0.1645 0.2088
Echinococcus granulosus Nicastrin 0.0056 0.0049 0.0077
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0204 0.0224 0.0285
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Trypanosoma brucei beta lactamase 0.0271 0.0304 0.1802
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0024 0.0126
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0288 0.0323 0.0364
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0226 0.025 0.0308
Plasmodium falciparum importin beta, putative 0.0036 0.0025 0.0168
Echinococcus granulosus dnaJ subfamily B 0.0285 0.032 0.0505
Brugia malayi N-terminal motif family protein 0.0023 0.0009 0.0009
Plasmodium vivax topoisomerase I, putative 0.0171 0.0185 0.1387
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0024 0.001 0.001
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0024 0.003
Schistosoma mansoni isocitrate dehydrogenase 0.0024 0.001 0.0012
Echinococcus multilocularis dro:myosuppressin receptor 0.0164 0.0177 0.0218
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0098 0.0098 0.011
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0282 0.0316 0.0316
Echinococcus granulosus snurportin 1 0.0389 0.0443 0.07
Echinococcus granulosus NADH dehydrogenase 0.0451 0.0517 0.0817
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0012
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.1121 0.1311 0.7821
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0277 0.0311 0.0351
Mycobacterium ulcerans Type I modular polyketide synthase 0.445 0.5259 0.6675
Trichomonas vaginalis sugar transporter, putative 0.0025 0.0011 0.0065
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0451 0.0517 0.3076
Schistosoma mansoni tyrosine kinase 0.0072 0.0067 0.0077
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0072 0.0067 0.0106
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0073 0.0069 0.0084
Onchocerca volvulus 0.0055 0.0047 0.0044
Entamoeba histolytica hypothetical protein 0.0212 0.0234 0.1379
Echinococcus granulosus WGR domain containing protein 0.0128 0.0133 0.021
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0062 0.0055 0.007
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0277 0.0311 0.0395
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0022 0.0021
Toxoplasma gondii ABC1 family protein 0.0031 0.0019 0.0031
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0024 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0002 0.0002
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0277 0.0311 0.1846
Brugia malayi Muscleblind-like protein 0.0254 0.0283 0.0283
Brugia malayi nuclear receptor NHR-88 0.0098 0.0098 0.0098
Brugia malayi CXXC zinc finger family protein 0.002 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0024
Loa Loa (eye worm) G-protein coupled receptor 0.0164 0.0177 0.0199
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0098 0.0098 0.0112
Echinococcus granulosus neuropeptide s receptor 0.0589 0.0681 0.1076
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0048 0.0039 0.0216
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0063 0.0372
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0024 0.0142
Onchocerca volvulus 0.0164 0.0177 0.018
Trichomonas vaginalis ran, putative 0.0027 0.0014 0.0079
Schistosoma mansoni acyl carrier protein 0.0451 0.0517 0.0591
Onchocerca volvulus 0.0164 0.0177 0.018
Echinococcus multilocularis protein dispatched 1 0.0092 0.0092 0.0113
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.3577 0.4224 0.5361
Brugia malayi steroid hormone receptor 0.0098 0.0098 0.0098
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.1114 0.1304 0.7777
Brugia malayi hypothetical protein 0.0046 0.0037 0.0036
Brugia malayi nuclear receptor RXR 0.0052 0.0043 0.0043
Echinococcus granulosus g protein coupled receptor 0.0164 0.0177 0.0279
Schistosoma mansoni hypothetical protein 0.0164 0.0177 0.0202
Echinococcus granulosus peptide allatostatin:somatostatin 0.0164 0.0177 0.0279
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0155 0.0191
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0024 0.0126
Giardia lamblia Tenascin precursor 0.002 0.0006 0.0016
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0197 0.0215 0.0246
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Trichomonas vaginalis ras GTP exchange factor, putative 0.0023 0.0009 0.0051
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0098 0.0098 0.0154
Plasmodium falciparum calcium-dependent protein kinase 4 0.0035 0.0024 0.0156
Leishmania major oxidoreductase, putative 0.0277 0.0311 0.1846
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0164 0.0177 0.0177
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Echinococcus granulosus fibrillin 1 0.002 0.0006 0.0009
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1428 0.1676 0.207
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.4727 0.5588 0.7093
Schistosoma mansoni hypothetical protein 0.0033 0.0022 0.0024
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.4727 0.5588 0.7093
Trypanosoma brucei glucose transporter 1E 0.0025 0.0011 0.0057
Trypanosoma cruzi acyl transferase-like protein, putative 0.0282 0.0316 0.1878
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0164 0.0177 0.0218
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0164 0.0177 0.0202
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0277 0.0311 0.0392
Mycobacterium ulcerans quinone oxidoreductase 0.0277 0.0311 0.0392
Echinococcus granulosus histone lysine methyltransferase setb 0.011 0.0112 0.0177
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0685 0.0794 0.1008
Toxoplasma gondii melibiase subfamily protein 0.009 0.0088 0.0155
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0024 0.0142
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.1121 0.1311 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0146 0.023
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.1121 0.1311 0.2073
Brugia malayi EGF-like domain containing protein 0.002 0.0006 0.0006
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0032 0.002 0.002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0069 0.0064 0.0378
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0098 0.0098 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0027 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Schistosoma mansoni zinc finger protein 0.0038 0.0027 0.003
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0048 0.0039 0.0224
Entamoeba histolytica hypothetical protein 0.003 0.0018 0.0089
Leishmania major protein kinase, putative 0.0026 0.0013 0.0066
Echinococcus multilocularis insulin receptor 0.0157 0.0168 0.0207
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Mycobacterium tuberculosis Conserved protein 0.0031 0.0019 0.0024
Brugia malayi intracellular kinase 0.0057 0.005 0.005
Echinococcus multilocularis integrin alpha ps 0.0106 0.0108 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0451 0.0517 0.3894
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0204 0.0224 0.0354
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0068 0.0063 0.0077
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0179 0.0195 0.0195
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0037 0.0036
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0045 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0024
Onchocerca volvulus 0.0164 0.0177 0.018
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0031 0.0027
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0027 0.0014 0.0071
Brugia malayi DKFZp564C0469 protein 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0005
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Echinococcus granulosus sterol regulatory element binding protein 0.0081 0.0078 0.0123
Echinococcus multilocularis sodium and chloride dependent glycine 0.0062 0.0056 0.0069
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0063 0.0372
Onchocerca volvulus Bile acid receptor homolog 0.0444 0.0509 0.0529
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0035 0.0024 0.0156
Schistosoma mansoni cytochrome P450 0.0017 0.0002 0.0002
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0023 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0035 0.0039
Loa Loa (eye worm) integrin alpha pat-2 0.0366 0.0416 0.0469
Leishmania major zinc binding dehydrogenase-like protein 0.0277 0.0311 0.1846
Onchocerca volvulus 0.7785 0.9213 0.9671
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0022 0.0117
Brugia malayi Furin-like cysteine rich region family protein 0.0072 0.0067 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0116 0.0119 0.0707
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0098 0.0098 0.011
Schistosoma mansoni hypothetical protein 0.0078 0.0075 0.0085
Trypanosoma brucei THT1 - hexose transporter, putative 0.0025 0.0011 0.0057
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0098 0.0098 0.0154
Brugia malayi latrophilin 2 splice variant baaae 0.0941 0.1098 0.1098
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0197 0.0215 0.0266
Echinococcus granulosus nibrin 0.0032 0.002 0.0031
Brugia malayi hypothetical protein 0.0032 0.002 0.002
Mycobacterium tuberculosis Possible dehydrogenase 0.0277 0.0311 0.0395
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0164 0.0177 0.0218
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0277 0.0311 0.1846
Plasmodium vivax ataxin-2 like protein, putative 0.0327 0.037 0.2801
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 0.1609
Echinococcus granulosus bloom syndrome protein 0.0017 0.0002 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0098 0.0098 0.0154
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.006 0.0053 0.006
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0081 0.0078 0.0136
Giardia lamblia Neurogenic locus Notch protein precursor 0.002 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0197 0.0215 0.1276
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trichomonas vaginalis Nicastrin precursor, putative 0.0056 0.0049 0.0288
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0027
Schistosoma mansoni pyruvate kinase 0.0029 0.0017 0.0019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0197 0.0215 0.0266
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0685 0.0794 0.1008
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0007
Schistosoma mansoni protein kinase 0.0035 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0464 0.0532 0.0676
Trypanosoma brucei oxidoreductase, putative 0.0277 0.0311 0.1846
Schistosoma mansoni dishevelled 0.0032 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0024
Schistosoma mansoni integrin alpha 0.0237 0.0263 0.0301
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.1121 0.1311 0.7821
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.008 0.0077 0.0122
Mycobacterium ulcerans quinone reductase Qor 0.0277 0.0311 0.0392
Mycobacterium tuberculosis Polyketide synthase Pks13 0.6658 0.7878 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0002 0.0002
Echinococcus granulosus presenilin enhancer 2 0.0108 0.0111 0.0175
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.003
Echinococcus granulosus dna polymerase eta 0.0033 0.0022 0.0034
Plasmodium vivax proline--tRNA ligase, putative 0.0028 0.0015 0.0092
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1377 0.1615 0.1614
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0277 0.0311 0.1846
Echinococcus granulosus GPCR family 2 0.0436 0.0499 0.0788
Schistosoma mansoni biogenic amine receptor 0.0164 0.0177 0.0202
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.3577 0.4224 0.5361
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0098 0.0098 0.0154
Treponema pallidum acyl carrier protein 0.0451 0.0517 0.3978
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Mycobacterium tuberculosis Possible penicillin-binding protein 0.02 0.0219 0.0279
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.445 0.5259 0.6676
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Loa Loa (eye worm) hypothetical protein 0.0685 0.0794 0.0896
Echinococcus multilocularis epidermal growth factor receptor 0.0072 0.0067 0.0083
Echinococcus multilocularis Niemann Pick C1 protein 0.027 0.0302 0.0373
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.1121 0.1311 1
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0464 0.0532 0.0676
Echinococcus granulosus mothers against decapentaplegic 5 0.0031 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Schistosoma mansoni [ACP] S-malonyltransferase 0.0282 0.0316 0.0361
Toxoplasma gondii type I fatty acid synthase, putative 0.3178 0.3751 0.6709
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0008 0.0009
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.0069 0.0504
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.1091 0.1276 0.1619
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Schistosoma mansoni biogenic amine (5HT) receptor 0.0427 0.0488 0.0558
Brugia malayi hypothetical protein 0.004 0.003 0.003
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0062 0.0056 0.0056
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0164 0.0177 0.0218
Echinococcus granulosus tachykinin peptides receptor 99D 0.0164 0.0177 0.0279
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1428 0.1676 0.1891
Echinococcus multilocularis expressed conserved protein 0.0177 0.0192 0.0237
Brugia malayi Importin beta-1 subunit 0.0036 0.0025 0.0025
Echinococcus granulosus g protein coupled receptor 0.0164 0.0177 0.0279
Brugia malayi Kelch motif family protein 0.0095 0.0095 0.0094
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0097 0.0097 0.0153
Mycobacterium ulcerans esterase/lipase LipP 0.0031 0.0019 0.0022
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0389 0.0443 0.0499
Brugia malayi putative neuropeptide receptor 0.0164 0.0177 0.0177
Brugia malayi Pax transcription activation domain interacting protein 0.0032 0.002 0.002
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0164 0.0177 0.0279
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0019 0.0103
Brugia malayi RE15519p 0.0164 0.0177 0.0177
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0024 0.001 0.0013
Loa Loa (eye worm) tnks protein 0.003 0.0018 0.002
Trypanosoma brucei pyruvate kinase 1, putative 0.0029 0.0017 0.0088
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0027 0.0014 0.0081
Toxoplasma gondii aldehyde dehydrogenase 0.0204 0.0224 0.0398
Schistosoma mansoni regulator of G protein signaling 0.0032 0.002 0.0023
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0037 0.0033
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0019 0.0111
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0166 0.0179 0.0205
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0048 0.0039 0.0048
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0464 0.0532 0.0676
Trypanosoma brucei glucosidase, putative 0.0036 0.0024 0.0134
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 0.9677
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 1
Schistosoma mansoni alpha glucosidase 0.0036 0.0024 0.0028
Schistosoma mansoni protein kinase 0.0035 0.0024 0.0027
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0019 0.0111
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0164 0.0177 0.0199
Onchocerca volvulus 0.4185 0.4945 0.5188
Schistosoma mansoni DNA polymerase eta 0.0033 0.0022 0.0024
Brugia malayi hypothetical protein 0.0046 0.0037 0.0036
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0031 0.0019 0.0024
Echinococcus granulosus 7tm_1 domain containing protein 0.0164 0.0177 0.0279
Trypanosoma cruzi oxidoreductase, putative 0.0277 0.0311 0.1846
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0002 0.0002
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.445 0.5259 0.6676
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0098 0.0098 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0453 0.0519 0.3084
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0136
Brugia malayi MH2 domain containing protein 0.0031 0.0018 0.0018
Trypanosoma brucei protein kinase, putative 0.0057 0.005 0.0287
Loa Loa (eye worm) AGC/PKG protein kinase 0.0026 0.0013 0.0014
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0038 0.0027 0.0023
Brugia malayi Pyruvate kinase, muscle isozyme 0.0029 0.0017 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0002 0.0002
Echinococcus granulosus cGMP dependent protein kinase 1 0.0026 0.0013 0.002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0173 0.0213
Schistosoma mansoni hypothetical protein 0.0451 0.0517 0.0591
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0048 0.0039 0.0223
Echinococcus multilocularis allatostatin A receptor 0.0164 0.0177 0.0218
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0023 0.0009 0.0051
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0024 0.0134
Brugia malayi photoreceptor-specific nuclear receptor 0.0264 0.0295 0.0295
Brugia malayi orphan nuclear receptor NR2E1 0.0046 0.0037 0.0036
Loa Loa (eye worm) sodium/hydrogen exchanger 3 family protein 0.0038 0.0027 0.003
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0116 0.0119 0.07
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.3668 0.4331 0.5352
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0155 0.0165 0.0189
Loa Loa (eye worm) hypothetical protein 0.0065 0.0059 0.0066
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0037 0.0026 0.0174
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0068 0.0063 0.0099
Schistosoma mansoni cpg binding protein 0.002 0.0006 0.0006
Loa Loa (eye worm) pyruvate kinase 0.0029 0.0017 0.0018
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0277 0.0311 0.0392
Trypanosoma brucei Aph-1 protein, putative 0.0107 0.0109 0.0641
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.0173 0.0195
Mycobacterium tuberculosis Possible dehydrogenase 0.0277 0.0311 0.0395
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0088 0.0101
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.3721 0.4394 0.5578
Schistosoma mansoni hypothetical protein 0.0732 0.085 0.0972
Plasmodium falciparum cGMP-dependent protein kinase 0.0026 0.0013 0.0075
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0277 0.0311 0.0392
Loa Loa (eye worm) hypothetical protein 0.0277 0.0311 0.0351
Echinococcus granulosus fmrfamide receptor 0.0164 0.0177 0.0279
Plasmodium falciparum acyl-CoA synthetase 0.0033 0.0021 0.0139
Toxoplasma gondii HEAT repeat-containing protein 0.0036 0.0025 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0019 0.0103
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0024 0.0011 0.0013
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0277 0.0311 0.1852
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.008 0.0077 0.0095
Trypanosoma cruzi polo-like protein kinase, putative 0.1428 0.1676 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Schistosoma mansoni opsin-like receptor 0.0164 0.0177 0.0202
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.002 0.0006 0.0032
Schistosoma mansoni topbp1 0.0032 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Schistosoma mansoni tyrosine kinase 0.0157 0.0168 0.0191
Schistosoma mansoni biogenic amine receptor 0.0164 0.0177 0.0202
Brugia malayi MH1 domain containing protein 0.0017 0.0002 0.0002
Trypanosoma cruzi hexose transporter, putative 0.0025 0.0011 0.0057
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Trypanosoma brucei ISWI complex protein 0.0026 0.0013 0.0064
Leishmania major DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Onchocerca volvulus 0.0164 0.0177 0.018
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.005 0.0056
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.002 0.0107
Echinococcus multilocularis MAM 0.0033 0.0022 0.0026
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0116 0.0119 0.0707
Leishmania major pyruvate kinase 0.0029 0.0017 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Onchocerca volvulus 0.0132 0.0139 0.014
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi Latrophilin receptor protein 2 0.0436 0.0499 0.0498
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0002 0.0002
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0436 0.0499 0.0616
Echinococcus multilocularis nibrin 0.0032 0.002 0.0024
Brugia malayi Isocitrate dehydrogenase 0.0197 0.0215 0.0215
Brugia malayi cytochrome P450 0.0017 0.0002 0.0002
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0057 0.005 0.0061
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0038 0.0027 0.0033
Giardia lamblia Kinase, CMGC GSK 0.0057 0.005 0.028
Toxoplasma gondii hypothetical protein 0.002 0.0006 0.0007
Schistosoma mansoni importin beta-1 0.0036 0.0025 0.0028
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Loa Loa (eye worm) hypothetical protein 0.0131 0.0137 0.0155
Loa Loa (eye worm) latrophilin receptor protein 2 0.0436 0.0499 0.0562
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.005 0.028
Trichomonas vaginalis chaperonin, putative 0.0022 0.0008 0.0044
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0282 0.0316 0.05
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0282 0.0316 0.2393
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0027 0.0014 0.0014
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.4727 0.5588 0.7093
Brugia malayi nuclear receptor NHR-67 0.0046 0.0037 0.0036
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0098 0.0098 0.0112
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0026 0.0144
Echinococcus multilocularis conserved hypothetical protein 0.05 0.0575 0.071
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi Serotonin receptor 0.0498 0.0572 0.0572
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Schistosoma mansoni myosin xvIII 0.0164 0.0177 0.0202
Toxoplasma gondii acyl transferase domain-containing protein 0.0282 0.0316 0.0562
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.005 0.0056
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Trypanosoma brucei unspecified product 0.0033 0.0022 0.0117
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0027 0.0144
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0027 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0013 0.0015
Plasmodium falciparum proline--tRNA ligase 0.0028 0.0015 0.0092
Loa Loa (eye worm) TK/EGFR protein kinase 0.0072 0.0067 0.0076
Loa Loa (eye worm) hypothetical protein 0.0132 0.0139 0.0156
Loa Loa (eye worm) sugar transporter 0.008 0.0077 0.0087
Echinococcus multilocularis Protein son of sevenless 0.0023 0.0009 0.0011
Echinococcus multilocularis thyroid hormone receptor alpha 0.0098 0.0098 0.0121
Schistosoma mansoni neuropeptide F-like receptor 0.0164 0.0177 0.0202
Loa Loa (eye worm) nuclear factor I 0.0017 0.0002 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0036 0.0202
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.003
Brugia malayi Presenilin spe-4 0.004 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi Cytochrome P450 family protein 0.0017 0.0002 0.0002
Trypanosoma cruzi Aph-1 protein, putative 0.0107 0.0109 0.0641
Schistosoma mansoni chromosome transmission fidelity factor 0.0032 0.002 0.0022
Loa Loa (eye worm) TYRA-2 protein 0.0164 0.0177 0.0199
Echinococcus granulosus PHD finger protein rhinoceros 0.0021 0.0007 0.001
Trichomonas vaginalis DNA helicase recq1, putative 0.0017 0.0002 0.001
Plasmodium falciparum protein kinase 6 0.0351 0.0398 0.3021
Leishmania major d-xylulose reductase, putative 0.0277 0.0311 0.1846
Loa Loa (eye worm) cytochrome P450 0.0017 0.0002 0.0002
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0038 0.0027 0.0033
Brugia malayi EGF-like domain containing protein 0.002 0.0006 0.0006
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0045 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.012 0.0124 0.0139
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0277 0.0311 0.1839
Schistosoma mansoni neuropeptide f receptor 76f 0.0164 0.0177 0.0202
Echinococcus multilocularis mothers against decapentaplegic 5 0.0031 0.0018 0.0022
Schistosoma mansoni smad1 5 8 and 0.0031 0.0018 0.0021
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0098 0.0098 0.0112
Schistosoma mansoni neuropeptide receptor 0.0164 0.0177 0.0202
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0036 0.0061
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0019 0.0022
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 0.9679
Schistosoma mansoni RAR-like nuclear receptor 0.0098 0.0098 0.0112
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0197 0.0215 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0077 0.0457
Echinococcus granulosus alpha 1A adrenergic receptor 0.0164 0.0177 0.0279
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0088 0.0101
Schistosoma mansoni sodium/hydrogen exchanger 2 (nhe2) 0.0038 0.0027 0.0031
Echinococcus granulosus sodium:hydrogen exchanger 2 (nhe2) 0.0031 0.0018 0.0029
Brugia malayi Cytochrome P450 family protein 0.0062 0.0055 0.0055
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1428 0.1676 1
Mycobacterium tuberculosis Probable lipase LipD 0.0031 0.0019 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Schistosoma mansoni chromobox protein 0.0068 0.0063 0.0072
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0032 0.002 0.002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.003 0.0017 0.0098
Leishmania major T-complex protein 1, beta subunit, putative 0.0022 0.0008 0.0036
Brugia malayi Calcitonin receptor-like protein seb-1 0.1377 0.1615 0.1614
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0565 0.0652 0.0828
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.3636 0.4294 0.5451
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0019 0.0024
Echinococcus multilocularis integrin alpha ps 0.0051 0.0042 0.0052
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0379 0.0431 0.0431
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Schistosoma mansoni ran 0.0027 0.0014 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0098 0.0098 0.0098
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0029
Chlamydia trachomatis acyl carrier protein 0.0451 0.0517 0.3927
Onchocerca volvulus Serine\/threonine kinase homolog 0.1428 0.1676 0.1755
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.4328 0.5115 0.6493
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0166 0.0179 0.0283
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0022 0.0024
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0038 0.0027 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0035 0.0042
Echinococcus multilocularis cpg binding protein 0.0024 0.0011 0.0013
Brugia malayi nuclear receptor NHR-88 0.0046 0.0037 0.0036
Echinococcus granulosus sex peptide receptor 0.0164 0.0177 0.0279
Plasmodium vivax hexose transporter 0.008 0.0077 0.0565
Entamoeba histolytica protein kinase, putative 0.0035 0.0024 0.0122
Echinococcus granulosus orexin receptor type 2 0.0164 0.0177 0.0279
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0064 0.037
Echinococcus multilocularis General substrate transporter 0.0069 0.0064 0.0078
Brugia malayi topoisomerase 0.0032 0.002 0.002
Onchocerca volvulus 0.0164 0.0177 0.018
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.0427 0.0488 0.055
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0652 0.0756 0.0852
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0027 0.0014 0.0071
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0016 0.0001 0.0000039885
Brugia malayi N-terminal motif family protein 0.0023 0.0009 0.0009
Onchocerca volvulus 0.002 0.0006 0.0001
Leishmania major 4-coumarate:coa ligase-like protein 0.0045 0.0035 0.0196
Schistosoma mansoni nuclear receptor 0.0046 0.0037 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0024 0.0134
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0164 0.0177 0.0279
Echinococcus multilocularis Smad4 0.0031 0.0018 0.0022
Loa Loa (eye worm) inositol-1 0.0069 0.0064 0.0072
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0427 0.0488 0.055
Onchocerca volvulus Pyruvate kinase homolog 0.0029 0.0017 0.0012
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Leishmania major lysyl-tRNA synthetase, putative 0.0018 0.0003 0.0008
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0147 0.0156 0.0192
Loa Loa (eye worm) hypothetical protein 0.2486 0.293 0.3307
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0081
Echinococcus granulosus G protein coupled receptor 139 0.0164 0.0177 0.0279
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.002 0.0115
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0064 0.037
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.002 0.0115
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0037 0.0026 0.0033
Loa Loa (eye worm) STE/STE11/ASK protein kinase 0.1114 0.1304 0.1471
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.4185 0.4945 0.6277
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0026 0.0033
Echinococcus granulosus Pleckstrin G protein interacting region 0.0032 0.002 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0098 0.0098 0.011
Echinococcus granulosus beta LACTamase domain containing family member 0.0031 0.0019 0.003
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0024 0.001 0.0012
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0031 0.0018 0.0022
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0024 0.0011 0.0044
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0464 0.0532 0.0673
Mycobacterium ulcerans polyketide synthase Pks9 0.2937 0.3465 0.4398
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0164 0.0177 0.0218
Plasmodium falciparum protein kinase 7 0.0237 0.0263 0.1989
Loa Loa (eye worm) hypothetical protein 0.0254 0.0283 0.0319
Brugia malayi RNA, U transporter 1 0.0104 0.0105 0.0104
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0264 0.0296 0.1755
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0116 0.0119 0.0707
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0197 0.0215 0.1276
Brugia malayi hypothetical protein 0.0271 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Loa Loa (eye worm) Smad1 0.0031 0.0018 0.002
Mycobacterium leprae Probable pyruvate kinase PykA 0.0029 0.0017 0.0021
Echinococcus granulosus pyruvate kinase 0.0029 0.0017 0.0026
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0035 0.0035
Onchocerca volvulus Putative alcohol dehydrogenase 0.0277 0.0311 0.0321
Loa Loa (eye worm) hypothetical protein 0.006 0.0053 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0098 0.0098 0.0098
Mycobacterium tuberculosis Polyketide synthase Pks12 0.4727 0.5588 0.7093
Loa Loa (eye worm) beta-lactamase 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Onchocerca volvulus Fatty acid synthase homolog 0.8049 0.9527 1
Loa Loa (eye worm) DIX domain-containing protein 0.0032 0.002 0.0022
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0002 0.0002
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0018 0.0003 0.0008
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0024 0.0011 0.001
Toxoplasma gondii histone lysine methyltransferase SET1 0.0048 0.0039 0.0067
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0277 0.0311 0.0392
Loa Loa (eye worm) acyl carrier protein 0.0451 0.0517 0.0583
Chlamydia trachomatis DNA ligase 0.0032 0.002 0.0127
Schistosoma mansoni nuclear receptor 0.0046 0.0037 0.0042
Echinococcus granulosus Niemann Pick C1 protein 0.0189 0.0206 0.0325
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0019 0.0024
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0036 0.0252
Echinococcus granulosus integrin beta 2 0.0464 0.0532 0.0841
Echinococcus granulosus Protein patched homolog 1 0.0081 0.0078 0.0123
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0453 0.0519 0.0656
Echinococcus multilocularis calcium dependent protein kinase 0.0023 0.0009 0.0011
Loa Loa (eye worm) sodium/hydrogen exchanger 0.0038 0.0027 0.003
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.2937 0.3465 0.4398
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0024 0.0027
Brugia malayi ecdysone receptor 0.0046 0.0037 0.0036
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0282 0.0316 0.2352
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0277 0.0311 0.1846
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0033 0.0037
Mycobacterium leprae putative cytochrome p450 0.0017 0.0002 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.0164 0.0177 0.0199
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0125 0.013 0.0768
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0436 0.0499 0.0498
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0366 0.0416 0.0469
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.1121 0.1311 0.1662
Onchocerca volvulus 0.0092 0.0091 0.009
Trypanosoma brucei DNA polymerase eta, putative 0.0033 0.0022 0.0117
Schistosoma mansoni integrin alpha-ps 0.0055 0.0048 0.0054
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0023 0.0009 0.001
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Brugia malayi MH2 domain containing protein 0.0451 0.0516 0.0516
Toxoplasma gondii exonuclease III APE 0.0048 0.0039 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0164 0.0177 0.0218
Echinococcus multilocularis G-protein coupled receptor, putative 0.0164 0.0177 0.0218
Trypanosoma brucei polo-like protein kinase 0.1428 0.1676 1
Onchocerca volvulus 0.0164 0.0177 0.018
Brugia malayi MH1 domain containing protein 0.0031 0.0018 0.0018
Loa Loa (eye worm) neuropeptide F receptor 0.0164 0.0177 0.0199
Giardia lamblia Neurogenic locus notch-like protein 0.002 0.0006 0.0016
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0166 0.0179 0.0179
Giardia lamblia hypothetical protein 0.002 0.0006 0.0016
Loa Loa (eye worm) RasGEF domain-containing protein 0.0023 0.0009 0.001
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Echinococcus granulosus biogenic amine 5HT receptor 0.0427 0.0488 0.0771
Echinococcus multilocularis beta LACTamase domain containing family member 0.0031 0.0019 0.0023
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0017 0.0019
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0031 0.0019 0.0022
Echinococcus granulosus protein kinase shaggy 0.0057 0.005 0.0079
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0018 0.0003 0.0008
Brugia malayi neuropeptide F receptor 0.0164 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0072 0.0068 0.0076
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0037 0.0026 0.0144
Brugia malayi hypothetical protein 0.0032 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0078 0.0462
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0031 0.018
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0164 0.0177 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0081

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.747 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.715 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.702 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.682 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.498 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.476 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.466 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.434 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.387 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.005 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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