Detailed information for compound 1650263

Basic information

Technical information
  • TDR Targets ID: 1650263
  • Name: 1,3-dibromo-5,5-dihydroxycyclopenta[c]thiophe ne-4,6-dione
  • MW: 341.961 | Formula: C7H2Br2O4S
  • H donors: 2 H acceptors: 4 LogP: 1.79 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1c2c(Br)sc(c2C(=O)C1(O)O)Br
  • InChi: 1S/C7H2Br2O4S/c8-5-1-2(6(9)14-5)4(11)7(12,13)3(1)10/h12-13H
  • InChiKey: CPYBQJIFYCVZDC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1,3-dibromo-5,5-dihydroxy-cyclopenta[c]thiophene-4,6-dione
  • 1,3-dibromo-5,5-dihydroxy-cyclopenta[c]thiophene-4,6-quinone
  • NCI60_038998
  • NSC710884

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0366 0.0416 0.0469
Onchocerca volvulus 0.0057 0.005 0.0047
Loa Loa (eye worm) integrin beta-2 0.0626 0.0724 0.0817
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0197 0.0215 0.0273
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0282 0.0316 0.2393
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Loa Loa (eye worm) isocitrate dehydrogenase 0.0197 0.0215 0.0243
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0035 0.0024 0.0156
Giardia lamblia High cysteine protein 0.002 0.0006 0.0016
Brugia malayi nuclear receptor RXR 0.0052 0.0043 0.0043
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0024 0.001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Leishmania major nuclear receptor binding factor-like protein 0.0277 0.0311 0.1846
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0027 0.0014 0.0017
Brugia malayi Bromodomain containing protein 0.0131 0.0138 0.0138
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0002 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0327 0.037 0.2196
Echinococcus granulosus expressed conserved protein 0.0177 0.0192 0.0304
Echinococcus granulosus g protein coupled receptor 0.0164 0.0177 0.0279
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0125 0.013 0.0768
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.001
Schistosoma mansoni protein kinase 0.0035 0.0024 0.0027
Schistosoma mansoni hypothetical protein 0.0732 0.085 0.0972
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0277 0.0311 0.0395
Schistosoma mansoni neuropeptide F-like receptor 0.0164 0.0177 0.0202
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1377 0.1615 0.1614
Trichomonas vaginalis Importin beta-1 subunit, putative 0.003 0.0017 0.0098
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0164 0.0177 0.0199
Onchocerca volvulus Serine\/threonine kinase homolog 0.1428 0.1676 0.1755
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Schistosoma mansoni dishevelled 0.0032 0.002 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0035 0.0024 0.0039
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0057 0.005 0.0057
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.0282 0.0316 0.2393
Trichomonas vaginalis hypothetical protein 0.002 0.0006 0.0032
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0204 0.0224 0.0354
Echinococcus multilocularis chromobox protein 1 0.0068 0.0063 0.0077
Loa Loa (eye worm) hypothetical protein 0.0325 0.0367 0.0414
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0166 0.0179 0.0221
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0024 0.0011 0.0012
Echinococcus multilocularis fibrillin 1 0.0029 0.0017 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0116 0.0119 0.07
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.0116 0.0119 0.07
Trypanosoma brucei Aph-1 protein, putative 0.0107 0.0109 0.0641
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0018 0.0003 0.0002
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0164 0.0177 0.0202
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0022 0.0008 0.0009
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Schistosoma mansoni adenoreceptor 0.0164 0.0177 0.0202
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0451 0.0517 0.0517
Giardia lamblia Tenascin-37 0.002 0.0006 0.0016
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0277 0.0311 0.0395
Leishmania major DNA repair protein, putative 0.002 0.0005 0.0019
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0282 0.0316 0.039
Echinococcus granulosus ras GTP exchange factor 0.0023 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0081 0.0078 0.0088
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0033 0.0021 0.0027
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi Kelch motif family protein 0.0095 0.0095 0.0094
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.0069 0.0504
Schistosoma mansoni glutaminase 0.1365 0.1601 0.1831
Schistosoma mansoni alpha-glucosidase 0.0139 0.0146 0.0167
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.002
Echinococcus granulosus cGMP dependent protein kinase 1 0.0026 0.0013 0.002
Onchocerca volvulus 0.0164 0.0177 0.018
Trichomonas vaginalis esterase, putative 0.0031 0.0019 0.0111
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0277 0.0311 0.0392
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0164 0.0177 0.018
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0277 0.0311 0.1852
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0277 0.0311 0.0395
Schistosoma mansoni steroid hormone receptor ad4bp 0.0098 0.0098 0.0112
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0179 0.0195 0.0195
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Echinococcus multilocularis dnaJ subfamily B 0.0285 0.032 0.0395
Echinococcus multilocularis neuropeptide FF receptor 2 0.0164 0.0177 0.0218
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0027 0.0014 0.0016
Echinococcus granulosus integrin alpha ps 0.0106 0.0108 0.0171
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Toxoplasma gondii melibiase subfamily protein 0.009 0.0088 0.0155
Trypanosoma cruzi Aph-1 protein, putative 0.0107 0.0109 0.0641
Mycobacterium ulcerans hypothetical protein 0.0139 0.0147 0.0184
Echinococcus granulosus Niemann Pick C1 protein 0.0189 0.0206 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0027 0.016
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0081 0.0078 0.0088
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Trichomonas vaginalis DNA helicase recq, putative 0.0017 0.0002 0.001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0064 0.037
Trypanosoma cruzi hexose transporter 0.0025 0.0011 0.0057
Leishmania major hypothetical protein, conserved 0.1345 0.1577 0.941
Loa Loa (eye worm) latrophilin receptor protein 2 0.0436 0.0499 0.0562
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 0.9679
Entamoeba histolytica hypothetical protein 0.0037 0.0026 0.0136
Loa Loa (eye worm) pyruvate kinase 0.0029 0.0017 0.0018
Entamoeba histolytica presenilin 1 peptidase, putative 0.0116 0.0119 0.0692
Onchocerca volvulus 0.0639 0.074 0.0772
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0031 0.0019 0.0019
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0565 0.0652 0.0825
Trypanosoma cruzi polo-like protein kinase, putative 0.1428 0.1676 1
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0277 0.0311 0.1846
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.008 0.0077 0.0122
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0027 0.0185
Brugia malayi conserved hypotetical protein 0.0046 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0189 0.0206 0.1212
Brugia malayi Inositol-1 0.0069 0.0064 0.0064
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0081 0.0078 0.0136
Echinococcus multilocularis conserved hypothetical protein 0.05 0.0575 0.071
Toxoplasma gondii hypothetical protein 0.004 0.003 0.005
Echinococcus multilocularis PHD finger protein rhinoceros 0.0021 0.0007 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0018 0.0003 0.0016
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0098 0.0098 0.0112
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Toxoplasma gondii exonuclease III APE 0.0048 0.0039 0.0067
Echinococcus multilocularis muscleblind protein 1 0.0254 0.0283 0.035
Loa Loa (eye worm) T-complex protein 1 0.0022 0.0008 0.0009
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0024 0.0011 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0013 0.0015
Echinococcus granulosus GTP binding nuclear protein Ran 0.0027 0.0014 0.0021
Mycobacterium tuberculosis Conserved protein 0.0031 0.0019 0.0024
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0035 0.0024 0.0156
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Echinococcus granulosus fetal alzheimer antigen falz 0.0039 0.0029 0.0045
Onchocerca volvulus 0.0045 0.0035 0.0031
Echinococcus multilocularis nibrin 0.0032 0.002 0.0024
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.1806 0.2123 0.2695
Brugia malayi hypothetical protein 0.004 0.003 0.003
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.1121 0.1311 1
Schistosoma mansoni hypothetical protein 0.0436 0.0499 0.057
Plasmodium falciparum calcium-dependent protein kinase 2 0.0035 0.0024 0.0156
Plasmodium falciparum hexose transporter 0.008 0.0077 0.0565
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0098 0.0098 0.0121
Echinococcus granulosus importin subunit beta 1 0.0036 0.0025 0.0039
Echinococcus granulosus chromobox protein 1 0.0068 0.0063 0.0099
Mycobacterium ulcerans oxidoreductase 0.0277 0.0311 0.0392
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0019 0.0024
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0033 0.0021 0.0025
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0024 0.001 0.0013
Echinococcus multilocularis integrin alpha ps 0.0106 0.0108 0.0133
Trypanosoma brucei importin beta-1 subunit, putative 0.0036 0.0025 0.0139
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0033 0.0021 0.0139
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.0024 0.001 0.0013
Echinococcus granulosus segment polarity protein dishevelled 0.0032 0.002 0.0031
Echinococcus multilocularis protein dispatched 1 0.0092 0.0092 0.0113
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0037 0.0026 0.0049
Schistosoma mansoni biogenic amine receptor 0.0164 0.0177 0.0202
Schistosoma mansoni hypothetical protein 0.0389 0.0443 0.0506
Toxoplasma gondii quinone oxidoreductase, putative 0.0277 0.0311 0.0553
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0027 0.0014 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0098 0.0098 0.0098
Onchocerca volvulus 0.002 0.0006 0.0001
Trichomonas vaginalis chaperonin, putative 0.0022 0.0008 0.0044
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0173 0.0213
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0155 0.0191
Schistosoma mansoni glucose transport protein 0.008 0.0077 0.0088
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.3668 0.4331 0.685
Plasmodium falciparum pyruvate kinase 0.0029 0.0017 0.0102
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0069 0.0064 0.0412
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Trichomonas vaginalis ran, putative 0.0027 0.0014 0.0079
Schistosoma mansoni biogenic amine receptor 0.0164 0.0177 0.0202
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.1343 0.1575 0.1801
Loa Loa (eye worm) melatonin receptor type 1A 0.0164 0.0177 0.0199
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0024 0.0142
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0027 0.0014 0.0015
Leishmania major zinc binding dehydrogenase-like protein 0.0277 0.0311 0.1846
Brugia malayi WGR domain containing protein 0.0293 0.0329 0.0329
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0019 0.0111
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0565 0.0652 0.0828
Trypanosoma brucei protein kinase, putative 0.0057 0.005 0.0287
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0451 0.0517 0.0537
Schistosoma mansoni opsin-like receptor 0.0164 0.0177 0.0202
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0046 0.0037 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0019 0.0103
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Schistosoma mansoni biogenic amine (5HT) receptor 0.5347 0.6323 0.7232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Plasmodium falciparum mitogen-activated protein kinase 2 0.014 0.0148 0.1109
Brugia malayi AKH receptor 0.0164 0.0177 0.0177
Brugia malayi DNA topoisomerase I 0.0171 0.0185 0.0184
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0031 0.0027
Echinococcus multilocularis fmrfamide receptor 0.0164 0.0177 0.0218
Loa Loa (eye worm) sodium/hydrogen exchanger 3 family protein 0.0038 0.0027 0.003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0098 0.0098 0.0098
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0007
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.445 0.5259 0.6676
Loa Loa (eye worm) hypothetical protein 0.0277 0.0311 0.0351
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0039 0.0029 0.0032
Giardia lamblia Neurogenic locus notch-like protein 0.002 0.0006 0.0016
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0048 0.0039 0.0224
Brugia malayi Bloom's syndrome protein homolog 0.0017 0.0002 0.0002
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0046 0.0037 0.0042
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0277 0.0311 0.0395
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0277 0.0311 0.0392
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus granulosus peptide allatostatin:somatostatin 0.0164 0.0177 0.0279
Brugia malayi Protein kinase domain containing protein 0.0281 0.0316 0.0316
Onchocerca volvulus 0.0464 0.0532 0.0554
Toxoplasma gondii hypothetical protein 0.002 0.0006 0.0007
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0024 0.001 0.001
Onchocerca volvulus Neuropeptide F receptor homolog 0.0164 0.0177 0.018
Echinococcus granulosus biogenic amine 5HT receptor 0.0427 0.0488 0.0771
Trypanosoma cruzi DNA repair protein, putative 0.002 0.0005 0.0019
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0063 0.0071
Schistosoma mansoni aldehyde dehydrogenase 0.0204 0.0224 0.0256
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0098 0.0098 0.0098
Schistosoma mansoni nuclear receptor 0.0046 0.0037 0.0042
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0007 0.0008
Mycobacterium ulcerans oxidoreductase FadB5 0.0277 0.0311 0.0392
Leishmania major oxidoreductase-like protein 0.0277 0.0311 0.1846
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0017 0.0019
Echinococcus multilocularis microtubule associated protein 2 0.2455 0.2893 0.3575
Loa Loa (eye worm) hypothetical protein 0.0051 0.0042 0.0048
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.1121 0.1311 0.2073
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0197 0.0215 0.0266
Brugia malayi putative neuropeptide receptor NPR1 0.0164 0.0177 0.0177
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0072 0.0067 0.0106
Entamoeba histolytica hypothetical protein 0.0212 0.0234 0.1379
Treponema pallidum acyl carrier protein 0.0451 0.0517 0.3978
Schistosoma mansoni ran 0.0027 0.0014 0.0015
Brugia malayi hypothetical protein 0.0046 0.0037 0.0036
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.002 0.0115
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Leishmania major acyl carrier protein, putative 0.0451 0.0517 0.3076
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0036 0.0202
Loa Loa (eye worm) TK/INSR protein kinase 0.0157 0.0168 0.0189
Schistosoma mansoni inositol monophosphatase 0.0069 0.0064 0.0073
Onchocerca volvulus 0.0164 0.0177 0.018
Brugia malayi nuclear hormone receptor 0.0046 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0002 0.0002
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0024 0.0011 0.0044
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0282 0.0316 0.2393
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0073 0.0069 0.0084
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Brugia malayi hypothetical protein 0.0052 0.0043 0.0043
Plasmodium falciparum cGMP-dependent protein kinase 0.0026 0.0013 0.0075
Entamoeba histolytica hypothetical protein 0.003 0.0018 0.0089
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0226 0.025 0.148
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.3577 0.4224 0.5361
Entamoeba histolytica acyl-CoA synthetase, putative 0.0045 0.0035 0.0189
Echinococcus granulosus Pleckstrin G protein interacting region 0.0032 0.002 0.0031
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0277 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0195 0.0213 0.024
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0035 0.0024 0.0129
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0031 0.0019 0.0021
Echinococcus multilocularis expressed conserved protein 0.0177 0.0192 0.0237
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0037 0.0026 0.0174
Schistosoma mansoni hypothetical protein 0.0732 0.085 0.0972
Loa Loa (eye worm) bromodomain containing protein 0.0033 0.0022 0.0024
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0024 0.001 0.0012
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0264 0.0296 0.1755
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0062 0.0055 0.007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0197 0.0215 0.0266
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0057 0.005 0.0079
Loa Loa (eye worm) DNA topoisomerase I 0.0171 0.0185 0.0208
Echinococcus granulosus g protein coupled receptor 0.0164 0.0177 0.0279
Mycobacterium ulcerans aldehyde dehydrogenase 0.0204 0.0224 0.0282
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.4185 0.4945 0.6277
Loa Loa (eye worm) hypothetical protein 0.0685 0.0794 0.0896
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.4727 0.5588 0.7093
Mycobacterium tuberculosis Hypothetical protein 0.1345 0.1577 0.2002
Echinococcus multilocularis integrin alpha ps 0.0106 0.0108 0.0133
Mycobacterium ulcerans lipase LipD 0.0031 0.0019 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0024
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0023 0.0026
Brugia malayi ecdysone receptor 0.0046 0.0037 0.0036
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.1085 0.1269 0.1611
Entamoeba histolytica hypothetical protein 0.0032 0.002 0.01
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0464 0.0532 0.0676
Brugia malayi Serotonin receptor 0.0164 0.0177 0.0177
Echinococcus multilocularis insulin receptor 0.0157 0.0168 0.0207
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.1114 0.1304 0.7777
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0002 0.0002
Toxoplasma gondii type I fatty acid synthase 0.0685 0.0794 0.1418
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0048 0.0039 0.0216
Brugia malayi hypothetical protein 0.0212 0.0234 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0039 0.0029 0.0035
Mycobacterium tuberculosis Conserved protein 0.0031 0.0019 0.0024
Echinococcus multilocularis adam 17 protease 0.0155 0.0165 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Echinococcus multilocularis replication factor c subunit 1 0.0032 0.002 0.0024
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0022 0.0027
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0068 0.0063 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Leishmania major glucose transporter, lmgt3 0.0025 0.0011 0.0057
Onchocerca volvulus 0.0164 0.0177 0.018
Leishmania major 4-coumarate:coa ligase-like protein 0.0045 0.0035 0.0196
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0052 0.0043 0.0068
Trypanosoma cruzi ISWI complex protein 0.0026 0.0013 0.0064
Schistosoma mansoni opsin-like receptor 0.0164 0.0177 0.0202
Onchocerca volvulus 0.0033 0.0022 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0379 0.0431 0.0431
Brugia malayi hypothetical protein 0.0032 0.002 0.002
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0197 0.0215 0.1276
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.445 0.5259 0.6676
Onchocerca volvulus 0.0164 0.0177 0.018
Brugia malayi DIX domain containing protein 0.0032 0.002 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0098 0.0098 0.011
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Schistosoma mansoni tyrosine kinase 0.0157 0.0168 0.0191
Echinococcus multilocularis epidermal growth factor receptor 0.0072 0.0067 0.0083
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0164 0.0177 0.0199
Plasmodium vivax pyruvate kinase, putative 0.0029 0.0017 0.0102
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0282 0.0316 0.2352
Giardia lamblia Kinase, CMGC GSK 0.0057 0.005 0.028
Plasmodium falciparum calcium-dependent protein kinase 3 0.0035 0.0024 0.0156
Toxoplasma gondii protein kinase, putative 0.0237 0.0263 0.0468
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.0116 0.0119 0.07
Schistosoma mansoni opsin-like receptor 0.0164 0.0177 0.0202
Plasmodium falciparum calcium-dependent protein kinase 4 0.0035 0.0024 0.0156
Schistosoma mansoni [ACP] S-malonyltransferase 0.0282 0.0316 0.0361
Plasmodium vivax replication factor C subunit 1, putative 0.0032 0.002 0.0127
Echinococcus multilocularis epidermal growth factor receptor 0.0072 0.0067 0.0083
Echinococcus granulosus PHD finger protein rhinoceros 0.0021 0.0007 0.001
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0453 0.0519 0.0659
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0037 0.0026 0.0174
Brugia malayi Cytochrome P450 family protein 0.0017 0.0002 0.0002
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.014 0.0148 0.1109
Brugia malayi steroid hormone receptor 0.0098 0.0098 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0098 0.0098 0.0098
Trypanosoma cruzi hypothetical protein 0.0023 0.0009 0.0043
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0008 0.0009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0081 0.0078 0.0096
Echinococcus multilocularis General substrate transporter 0.0069 0.0064 0.0078
Schistosoma mansoni tyrosine kinase 0.0069 0.0064 0.0073
Echinococcus granulosus calcium dependent protein kinase 0.0023 0.0009 0.0014
Chlamydia trachomatis acyl carrier protein 0.0451 0.0517 0.3927
Brugia malayi gamma-secretase subunit aph-1 0.0276 0.0309 0.0308
Entamoeba histolytica hypothetical protein 0.003 0.0018 0.0089
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0128 0.0134 0.0787
Echinococcus multilocularis pyruvate kinase 0.0029 0.0017 0.002
Schistosoma mansoni neuropeptide receptor 0.0164 0.0177 0.0202
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0018 0.0003 0.0002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0024 0.0142
Brugia malayi ecdysteroid receptor 0.0444 0.0509 0.0509
Mycobacterium ulcerans quinone oxidoreductase 0.0277 0.0311 0.0392
Onchocerca volvulus Fatty acid synthase homolog 0.8049 0.9527 1
Brugia malayi AMP-binding enzyme family protein 0.1375 0.1612 0.1612
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0027 0.0014 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0098 0.0098 0.0098
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Echinococcus granulosus cGMP dependent protein kinase 0.0026 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0012
Giardia lamblia Kinase, PLK 0.1428 0.1676 1
Loa Loa (eye worm) RasGEF domain-containing protein 0.0023 0.0009 0.001
Echinococcus granulosus dro:myosuppressin receptor 0.0164 0.0177 0.0279
Toxoplasma gondii acyl carrier protein ACP 0.0451 0.0517 0.0921
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trypanosoma brucei polo-like protein kinase 0.1428 0.1676 1
Onchocerca volvulus Putative alcohol dehydrogenase 0.0277 0.0311 0.0321
Giardia lamblia Replication factor C, subunit 1 0.0032 0.002 0.01
Schistosoma mansoni neuropeptide receptor 0.0164 0.0177 0.0202
Loa Loa (eye worm) acyl carrier protein 0.2053 0.2417 0.2727
Giardia lamblia Neurogenic locus Notch protein precursor 0.002 0.0006 0.0016
Brugia malayi EGF-like domain containing protein 0.002 0.0006 0.0006
Echinococcus granulosus geminin 0.0732 0.085 0.1344
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0022 0.0008 0.0044
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 0.9679
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0116 0.0119 0.07
Onchocerca volvulus 0.7785 0.9213 0.9671
Loa Loa (eye worm) hypothetical protein 0.0131 0.0137 0.0155
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0024 0.001 0.001
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0685 0.0794 0.1008
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Echinococcus multilocularis g-protein coupled receptor 0.0164 0.0177 0.0218
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0019 0.0024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0098 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.2486 0.293 0.3307
Trichomonas vaginalis CAMK family protein kinase 0.0711 0.0825 0.4921
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0022 0.0008 0.0012
Echinococcus granulosus poly (ADP ribose) polymerase 0.0128 0.0133 0.021
Giardia lamblia Kinase, CMGC GSK 0.0057 0.005 0.028
Loa Loa (eye worm) TYRA-2 protein 0.0164 0.0177 0.0199
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.0043 0.0033 0.0185
Brugia malayi cytochrome P450 0.0017 0.0002 0.0002
Echinococcus granulosus sodium:hydrogen exchanger 0.0038 0.0027 0.0042
Trichomonas vaginalis inositol monophosphatase, putative 0.0069 0.0064 0.0378
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Echinococcus granulosus segment polarity protein dishevelled 0.0032 0.002 0.0031
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0027 0.0014 0.0021
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus granulosus protein kinase shaggy 0.0057 0.005 0.0079
Trypanosoma brucei THT1 - hexose transporter, putative 0.0025 0.0011 0.0057
Echinococcus granulosus neuropeptide receptor A26 0.0589 0.0681 0.1076
Echinococcus multilocularis thyroid hormone receptor alpha 0.0098 0.0098 0.0121
Entamoeba histolytica pyruvate kinase, putative 0.002 0.0006 0.0017
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0128 0.0134 0.0787
Echinococcus multilocularis cpg binding protein 0.0024 0.0011 0.0013
Brugia malayi RE15519p 0.0164 0.0177 0.0177
Onchocerca volvulus 0.0093 0.0092 0.0092
Schistosoma mansoni Smad4 0.0031 0.0018 0.0021
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0048 0.0039 0.0216
Echinococcus granulosus 7tm_1 domain containing protein 0.0164 0.0177 0.0279
Schistosoma mansoni survival motor neuron protein 0.0055 0.0047 0.0054
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0027 0.0014 0.0063
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.6658 0.7878 1
Echinococcus multilocularis Protein son of sevenless 0.0023 0.0009 0.0011
Loa Loa (eye worm) AMP-binding enzyme family protein 0.4185 0.4945 0.558
Plasmodium falciparum importin beta, putative 0.0036 0.0025 0.0168
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0288 0.0323 0.0364
Brugia malayi hypothetical protein 0.0046 0.0037 0.0036
Brugia malayi Niemann-Pick C1 protein precursor 0.0189 0.0206 0.0206
Schistosoma mansoni hypothetical protein 0.0164 0.0177 0.0202
Schistosoma mansoni protein kinase 0.0035 0.0024 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.1428 0.1676 0.1917
Brugia malayi nuclear hormone receptor 0.0098 0.0098 0.0098
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0043 0.0043
Mycobacterium ulcerans dehydrogenase 0.0277 0.0311 0.0392
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0037 0.0045
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0038 0.0027 0.0033
Echinococcus granulosus sodium and chloride dependent glycine 0.0062 0.0056 0.0088
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0164 0.0177 0.0218
Trichomonas vaginalis replication factor C large subunit, putative 0.0032 0.002 0.0115
Schistosoma mansoni ran 0.0027 0.0014 0.0015
Schistosoma mansoni ap endonuclease 0.0048 0.0039 0.0045
Trichomonas vaginalis ap endonuclease, putative 0.0048 0.0039 0.0232
Loa Loa (eye worm) NHE-3 0.0038 0.0027 0.003
Plasmodium falciparum glycogen synthase kinase 3 0.0057 0.005 0.0358
Trypanosoma cruzi oxidoreductase, putative 0.0277 0.0311 0.1846
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0077 0.0457
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0277 0.0311 0.0311
Schistosoma mansoni thyroid hormone receptor 0.0098 0.0098 0.0112
Schistosoma mansoni hypothetical protein 0.0033 0.0022 0.0024
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0098 0.0098 0.0121
Echinococcus multilocularis g protein coupled receptor 0.0164 0.0177 0.0218
Echinococcus multilocularis segment polarity protein dishevelled 0.0032 0.002 0.0024
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0029
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0048 0.0039 0.0223
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.1121 0.1311 0.1311
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi Presenilin spe-4 0.004 0.003 0.003
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0055 0.0062
Schistosoma mansoni isocitrate dehydrogenase 0.0024 0.001 0.0012
Mycobacterium ulcerans polyketide synthase MbtC 0.1121 0.1311 0.1662
Onchocerca volvulus 0.0031 0.0019 0.0015
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0164 0.0177 0.0177
Mycobacterium tuberculosis Probable oxidoreductase 0.0277 0.0311 0.0395
Onchocerca volvulus 0.0098 0.0098 0.0097
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0197 0.0215 0.0266
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.0031
Echinococcus granulosus dnaJ subfamily B 0.0285 0.032 0.0505
Echinococcus multilocularis dna polymerase kappa 0.0033 0.0022 0.0026
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0024 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0005
Loa Loa (eye worm) TK/EGFR protein kinase 0.0072 0.0067 0.0076
Brugia malayi hypothetical protein 0.0095 0.0095 0.0094
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0271 0.0304 0.0385
Echinococcus granulosus epidermal growth factor receptor 0.0072 0.0067 0.0106
Plasmodium vivax hexose transporter 0.008 0.0077 0.0565
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0048 0.0039 0.0277
Echinococcus multilocularis serotonin receptor 0.0427 0.0488 0.0602
Schistosoma mansoni pyruvate kinase 0.0029 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0011 0.0012
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0032 0.002 0.0022
Echinococcus multilocularis tankyrase 0.003 0.0018 0.0022
Schistosoma mansoni DNA topoisomerase type I 0.0128 0.0134 0.0153
Echinococcus multilocularis neuropeptide s receptor 0.0589 0.0681 0.0841
Brugia malayi RNA recognition motif domain containing protein 0.0288 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0045 0.0035 0.0039
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 0.1609
Schistosoma mansoni glucose transport protein 0.008 0.0077 0.0088
Entamoeba histolytica hypothetical protein 0.0021 0.0007 0.002
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0195 0.0213 0.0244
Loa Loa (eye worm) MH2 domain-containing protein 0.0451 0.0516 0.0582
Brugia malayi N-terminal motif family protein 0.0652 0.0756 0.0755
Schistosoma mansoni hypothetical protein 0.0035 0.0023 0.0026
Schistosoma mansoni protein kinase 0.3668 0.4331 0.4954
Echinococcus multilocularis ras GTP exchange factor 0.0023 0.0009 0.0011
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0026 0.0013 0.002
Brugia malayi hypothetical protein 0.0033 0.0022 0.0021
Trypanosoma cruzi polo-like protein kinase, putative 0.1428 0.1676 1
Echinococcus multilocularis protein jagged 2 0.002 0.0006 0.0007
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.2937 0.3465 0.4399
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Echinococcus granulosus insulin receptor 0.0157 0.0168 0.0265
Loa Loa (eye worm) hypothetical protein 0.0245 0.0273 0.0308
Brugia malayi RNA binding protein 0.0288 0.0323 0.0323
Trypanosoma brucei oxidoreductase, putative 0.0277 0.0311 0.1846
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0027 0.0023
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0032 0.002 0.0025
Echinococcus granulosus neuropeptide receptor 0.0164 0.0177 0.0279
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Trypanosoma brucei oxidoreductase, putative 0.0277 0.0311 0.1846
Brugia malayi RasGEF domain containing protein 0.0023 0.0009 0.0009
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.2258 0.266 0.4757
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0379 0.0431 0.0493
Schistosoma mansoni integrin alpha 0.0237 0.0263 0.0301
Mycobacterium leprae Probable pyruvate kinase PykA 0.0029 0.0017 0.0021
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0464 0.0532 0.0673
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0277 0.0311 0.1846
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.008 0.0077 0.0095
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Mycobacterium ulcerans beta-lactamase 0.0031 0.0019 0.0022
Loa Loa (eye worm) integrin alpha pat-2 0.0366 0.0416 0.0469
Brugia malayi Pyruvate kinase, muscle isozyme 0.0029 0.0017 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Trypanosoma brucei THT1 - hexose transporter, putative 0.0025 0.0011 0.0057
Brugia malayi Neuronal symmetry protein 1 0.3668 0.4331 0.4331
Echinococcus multilocularis gamma secretase subunit aph 1 0.0276 0.0309 0.0381
Schistosoma mansoni bromodomain containing protein 0.0112 0.0114 0.0131
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0074 0.0069 0.0085
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1428 0.1676 0.1891
Echinococcus multilocularis g protein coupled receptor 0.0164 0.0177 0.0218
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0088 0.0101
Loa Loa (eye worm) hypothetical protein 0.0282 0.0316 0.0357
Onchocerca volvulus 0.0164 0.0177 0.018
Toxoplasma gondii isocitrate dehydrogenase 0.0197 0.0215 0.0382
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.008 0.0077 0.0095
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0282 0.0316 0.05
Echinococcus granulosus FTZ F1 alpha 0.0098 0.0098 0.0154
Entamoeba histolytica acyl-CoA synthetase, putative 0.0453 0.0519 0.3084
Echinococcus multilocularis Glycoside hydrolase, family 27 0.009 0.0088 0.0109
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0293 0.0329 0.0407
Loa Loa (eye worm) tnks protein 0.003 0.0018 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0024 0.0142
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0277 0.0311 0.1846
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0098 0.0098 0.0098
Echinococcus granulosus sodium and chloride dependent glycine 0.0062 0.0056 0.0088
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.3668 0.4331 0.5352
Echinococcus granulosus Nicastrin 0.0056 0.0049 0.0077
Brugia malayi hypothetical protein 0.0056 0.0049 0.0049
Echinococcus granulosus replication factor c subunit 1 0.0032 0.002 0.0031
Mycobacterium ulcerans esterase/lipase LipP 0.0031 0.0019 0.0022
Brugia malayi Sugar transporter family protein 0.008 0.0077 0.0077
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0685 0.0794 0.1008
Trypanosoma cruzi oxidoreductase, putative 0.0277 0.0311 0.1846
Onchocerca volvulus 0.0046 0.0037 0.0033
Schistosoma mansoni chromobox protein 0.0068 0.0063 0.0072
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0764 0.0888 0.1097
Loa Loa (eye worm) hypothetical protein 0.0327 0.037 0.0417
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0063 0.0372
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0037 0.0026 0.0121
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Toxoplasma gondii isocitrate dehydrogenase 0.0197 0.0215 0.0382
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0016 0.0001 0.0000039885
Echinococcus granulosus poly ADP ribose polymerase 1 0.0293 0.0329 0.0521
Plasmodium vivax proline--tRNA ligase, putative 0.0028 0.0015 0.0092
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.445 0.5259 0.6676
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0017 0.0019
Mycobacterium ulcerans polyketide synthase Pks13 0.6658 0.7878 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0023 0.0009 0.0043
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.4727 0.5588 0.7093
Schistosoma mansoni cpg binding protein 0.0024 0.0011 0.0012
Brugia malayi chromobox protein homolog 3 0.0038 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0022 0.011
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0022 0.0024
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0027 0.0144
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.005 0.0056
Echinococcus multilocularis segment polarity protein dishevelled 0.0032 0.002 0.0024
Toxoplasma gondii pyruvate kinase PyK1 0.0029 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0017 0.0018
Entamoeba histolytica Ran family GTPase 0.0027 0.0014 0.0063
Entamoeba histolytica protein kinase, putative 0.0057 0.005 0.028
Leishmania major glucose transporter, lmgt1 0.0025 0.0011 0.0057
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0038 0.0027 0.0033
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0037 0.0045
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0073 0.0069 0.0078
Brugia malayi Pax transcription activation domain interacting protein 0.0032 0.002 0.002
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.3577 0.4224 0.5361
Brugia malayi latrophilin 2 splice variant baaae 0.0941 0.1098 0.1098
Echinococcus granulosus poly (ADP ribose) polymerase 0.0064 0.0058 0.0091
Trypanosoma brucei unspecified product 0.0023 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0155 0.0155
Echinococcus granulosus chromobox protein 1 0.0068 0.0063 0.0099
Schistosoma mansoni tyrosine kinase 0.0072 0.0067 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Loa Loa (eye worm) hypothetical protein 0.0062 0.0056 0.0063
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Trypanosoma cruzi importin beta-1 subunit, putative 0.003 0.0017 0.009
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.1121 0.1311 1
Echinococcus multilocularis importin subunit beta 1 0.0036 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0451 0.0517 0.0591
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0197 0.0215 0.1623
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.1373 0.161 0.2044
Brugia malayi Muscleblind-like protein 0.0254 0.0283 0.0283
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0098 0.0098 0.0154
Echinococcus granulosus 7TM GPCR rhodopsin 0.0164 0.0177 0.0279
Brugia malayi WGR domain containing protein 0.0226 0.025 0.0249
Echinococcus granulosus ecdysone induced protein 78C 0.0098 0.0098 0.0154
Schistosoma mansoni biogenic amine receptor 0.0164 0.0177 0.0202
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0685 0.0794 0.1008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0024
Echinococcus multilocularis 0.0017 0.0002 0.0002
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0037 0.0026 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0166 0.0179 0.0205
Schistosoma mansoni nuclear hormone receptor 0.0098 0.0098 0.0112
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0024
Schistosoma mansoni sodium/chloride dependent transporter 0.0062 0.0056 0.0064
Leishmania major GTP-binding protein, putative 0.0027 0.0014 0.0071
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0028 0.0015 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0002 0.0002
Trichomonas vaginalis pyruvate kinase, putative 0.0029 0.0017 0.0096
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0098 0.0098 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Onchocerca volvulus 0.0046 0.0037 0.0033
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0031 0.0019 0.0024
Brugia malayi Heterochromatin protein 1 0.0068 0.0063 0.0063
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0024 0.001 0.0012
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0019 0.0004 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0013 0.0015
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0164 0.0177 0.0199
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0164 0.0177 0.0202
Toxoplasma gondii acyl transferase domain-containing protein 0.0282 0.0316 0.0562
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0164 0.0177 0.0218
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.1085 0.1269 0.9679
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0057 0.005 0.0287
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0277 0.0311 0.0392
Loa Loa (eye worm) transcription factor SMAD2 0.0451 0.0516 0.0582
Echinococcus multilocularis AMP dependent ligase 0.0453 0.0519 0.0641
Echinococcus granulosus neuropeptide Y receptor 0.0164 0.0177 0.0279
Echinococcus granulosus poly (ADP ribose) polymerase 0.0064 0.0058 0.0091
Brugia malayi nuclear hormone receptor family member nhr-6 0.0046 0.0037 0.0036
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.445 0.5259 0.6676
Onchocerca volvulus 0.0164 0.0177 0.018
Leishmania major 4-coumarate:coa ligase-like protein 0.0045 0.0035 0.0196
Echinococcus multilocularis presenilin enhancer 2 0.0108 0.0111 0.0136
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0031 0.0019 0.0024
Mycobacterium tuberculosis Probable thioesterase TesA 0.3721 0.4394 0.5578
Echinococcus multilocularis lysyl tRNA synthetase 0.0018 0.0003 0.0004
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0088 0.0101
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.2897 0.3417 0.6111
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0451 0.0517 0.3076
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0017 0.0019
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0277 0.0311 0.0395
Echinococcus granulosus sex peptide receptor 0.0164 0.0177 0.0279
Brugia malayi sulfakinin receptor protein 0.0164 0.0177 0.0177
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0031 0.0018 0.0021
Brugia malayi EGF-like domain containing protein 0.002 0.0006 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0002 0.0002
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0116 0.0119 0.0707
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0164 0.0177 0.0199
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0023 0.0009 0.0014
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.1403 0.1645 0.2088
Onchocerca volvulus 0.003 0.0018 0.0013
Echinococcus granulosus orexin receptor type 2 0.0164 0.0177 0.0279
Echinococcus granulosus nibrin 0.0032 0.002 0.0031
Mycobacterium leprae Conserved hypothetical protein 0.0017 0.0002 0.0002
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.1121 0.1311 0.7821
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0277 0.0311 0.0392
Echinococcus multilocularis regulator of G protein signaling 7 0.0032 0.002 0.0024
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Plasmodium falciparum phd finger protein, putative 0.0021 0.0007 0.0026
Leishmania major protein kinase, putative 0.0035 0.0024 0.0129
Echinococcus multilocularis neuropeptides capa receptor 0.0164 0.0177 0.0218
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0164 0.0177 0.0279
Loa Loa (eye worm) TAR-binding protein 0.0288 0.0323 0.0364
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0027 0.016
Toxoplasma gondii facilitative glucose transporter GT1 0.008 0.0077 0.0135
Brugia malayi Presenilin spe-4 0.004 0.003 0.003
Schistosoma mansoni cpg binding protein 0.002 0.0006 0.0006
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0057 0.005 0.0061
Toxoplasma gondii ABC1 family protein 0.0031 0.0019 0.0031
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0436 0.0499 0.0616
Schistosoma mansoni lysyl-tRNA synthetase 0.0018 0.0003 0.0003
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0002 0.0002
Onchocerca volvulus 0.002 0.0006 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Entamoeba histolytica zinc finger protein, putative 0.003 0.0018 0.0089
Onchocerca volvulus Pyruvate kinase homolog 0.0029 0.0017 0.0012
Giardia lamblia Tenascin precursor 0.002 0.0006 0.0016
Brugia malayi Cytochrome P450 family protein 0.0017 0.0002 0.0002
Schistosoma mansoni zinc finger protein 0.0026 0.0013 0.0014
Brugia malayi hypothetical protein 0.004 0.003 0.003
Trypanosoma brucei acyl transferase-like protein 0.0282 0.0316 0.1878
Entamoeba histolytica acyl-CoA synthetase, putative 0.0496 0.057 0.3386
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0098 0.0098 0.0098
Trypanosoma brucei glucose transporter 2A 0.0025 0.0011 0.0057
Schistosoma mansoni sodium/hydrogen exchanger 0.0038 0.0027 0.0031
Schistosoma mansoni nuclear receptor nhr-48 0.0046 0.0037 0.0042
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0036 0.0041
Echinococcus multilocularis orexin receptor type 2 0.0164 0.0177 0.0218
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0352 0.0399 0.045
Schistosoma mansoni retinoic acid receptor RXR 0.0098 0.0098 0.0112
Schistosoma mansoni smad 0.0031 0.0018 0.0021
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0036 0.0213
Mycobacterium ulcerans DNA polymerase IV 0.0033 0.0022 0.0025
Brugia malayi CHE-14 protein 0.0081 0.0078 0.0078
Echinococcus granulosus allatostatin A receptor 0.0164 0.0177 0.0279
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0164 0.0177 0.018
Echinococcus granulosus methyl CpG binding domain protein 2 0.0029 0.0016 0.0025
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0464 0.0532 0.0673
Chlamydia trachomatis DNA ligase 0.0032 0.002 0.0127
Brugia malayi larval opioid receptor 0.0164 0.0177 0.0177
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0045 0.0035 0.0044
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.1121 0.1311 0.2343
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0019 0.0022
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0157 0.0168 0.0207
Loa Loa (eye worm) hypothetical protein 0.0056 0.0049 0.0055
Loa Loa (eye worm) glutaminase 0.1365 0.1601 0.1806
Mycobacterium ulcerans polyketide synthase 0.445 0.5259 0.6675
Schistosoma mansoni hypothetical protein 0.0033 0.0022 0.0024
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0277 0.0311 0.0553
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0036 0.0061
Brugia malayi Phosphopantetheine attachment site family protein 0.0451 0.0517 0.0517
Echinococcus granulosus Niemann Pick C1 protein 0.027 0.0302 0.0477
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0098 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Mycobacterium tuberculosis Probable lipase LipE 0.0031 0.0019 0.0024
Trypanosoma brucei Presenilin enhancer-2 subunit of gamma secretase, putative 0.0033 0.0021 0.0112
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0293 0.0329 0.0377
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0046 0.0037 0.0041
Schistosoma mansoni hypothetical protein 0.0164 0.0177 0.0202
Brugia malayi orphan nuclear receptor NR2E1 0.0046 0.0037 0.0036
Onchocerca volvulus 0.4185 0.4945 0.5188
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0035 0.0042
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0008 0.0009
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0036 0.0213
Trichomonas vaginalis DNA polymerase eta, putative 0.0033 0.0022 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0019 0.0122
Trypanosoma cruzi Nicastrin, putative 0.0021 0.0007 0.0027
Echinococcus granulosus General substrate transporter 0.0069 0.0064 0.01
Leishmania major hypothetical protein, conserved 0.0031 0.0019 0.0103
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Entamoeba histolytica acyl-coA synthetase, putative 0.0045 0.0035 0.0189
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0031 0.018
Brugia malayi MH1 domain containing protein 0.0031 0.0018 0.0018
Brugia malayi Presenilin spe-4 0.004 0.003 0.003
Brugia malayi CXXC zinc finger family protein 0.002 0.0006 0.0005
Brugia malayi Egg laying defective protein 4 0.0026 0.0013 0.0013
Onchocerca volvulus 0.0164 0.0177 0.018
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0019 0.0024
Brugia malayi nuclear receptor RXR 0.0046 0.0037 0.0036
Schistosoma mansoni cpg binding protein 0.0024 0.0011 0.0012
Echinococcus multilocularis calcium dependent protein kinase 0.0023 0.0009 0.0011
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.4727 0.5588 0.7093
Brugia malayi hypothetical protein 0.0032 0.002 0.002
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0074 0.0069 0.0109
Brugia malayi AMP-binding enzyme family protein 0.4185 0.4945 0.4944
Loa Loa (eye worm) hypothetical protein 0.0652 0.0756 0.0852
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trypanosoma cruzi Aph-1 protein, putative 0.0107 0.0109 0.0641
Echinococcus multilocularis L aminoadipate semialdehyde 0.0132 0.0139 0.0171
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0098 0.0098 0.0121
Echinococcus multilocularis nuclear receptor nhr 48 0.0046 0.0037 0.0045
Echinococcus multilocularis lysine specific demethylase 5A 0.0025 0.0012 0.0014
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0046 0.0037 0.0036
Schistosoma mansoni hypothetical protein 0.0051 0.0042 0.0048
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Plasmodium vivax acyl-CoA synthetase, putative 0.0033 0.0021 0.0139
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0098 0.0098 0.011
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0098 0.0098 0.0098
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0277 0.0311 0.1846
Echinococcus granulosus microtubule associated protein 2 0.2455 0.2893 0.4576
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0098 0.0098 0.0112
Trichomonas vaginalis glucose transporter, putative 0.0025 0.0011 0.0065
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0264 0.0296 0.1755
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0024 0.0142
Trypanosoma cruzi oxidoreductase, putative 0.0277 0.0311 0.1846
Plasmodium falciparum acyl-CoA synthetase 0.0033 0.0021 0.0139
Giardia lamblia Pyruvate kinase 0.0029 0.0017 0.008
Echinococcus multilocularis neuropeptide Y receptor 0.0164 0.0177 0.0218
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0035 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0078 0.0089
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.012 0.0124 0.0139
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Schistosoma mansoni lysyl-tRNA synthetase 0.0018 0.0003 0.0003
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.4727 0.5588 0.7093
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0451 0.0517 0.3076
Brugia malayi neuropeptide F receptor 0.0164 0.0177 0.0177
Schistosoma mansoni thyroid hormone receptor 0.0098 0.0098 0.0112
Trypanosoma cruzi FHA domain containing protein, putative 0.0032 0.002 0.0107
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Echinococcus granulosus lysine specific demethylase 5A 0.003 0.0017 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0064 0.037
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0024 0.004
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.005 0.0295
Schistosoma mansoni neuropeptide f receptor 76f 0.0164 0.0177 0.0202
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0033 0.0037
Loa Loa (eye worm) beta-lactamase 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0277 0.0311 0.0351
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Schistosoma mansoni aldehyde dehydrogenase 0.0204 0.0224 0.0256
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Mycobacterium ulcerans Type I modular polyketide synthase 0.445 0.5259 0.6675
Brugia malayi nuclear receptor NHR-67 0.0046 0.0037 0.0036
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0037 0.0026 0.0043
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0197 0.0215 0.034
Loa Loa (eye worm) hypothetical protein 0.0045 0.0035 0.0039
Echinococcus multilocularis muscleblind protein 0.0254 0.0283 0.035
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0464 0.0532 0.0673
Mycobacterium tuberculosis Polyketide synthase Pks13 0.6658 0.7878 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trypanosoma cruzi hypothetical protein 0.0023 0.0009 0.0043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0098 0.0098 0.0121
Mycobacterium ulcerans quinone reductase Qor 0.0277 0.0311 0.0392
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.0069 0.012
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0164 0.0177 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.002 0.0107
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0023 0.0009 0.0011
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.002 0.0006 0.0032
Echinococcus granulosus NADH dehydrogenase 0.0451 0.0517 0.0817
Echinococcus granulosus integrin alpha 3 0.0182 0.0198 0.0312
Brugia malayi Protein kinase domain containing protein 0.0087 0.0085 0.0085
Schistosoma mansoni integrin alpha-ps 0.0106 0.0108 0.0123
Brugia malayi RasGEF domain containing protein 0.0023 0.0009 0.0009
Onchocerca volvulus 0.0164 0.0177 0.018
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0048 0.0039 0.0044
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.011 0.0112 0.0128
Echinococcus granulosus hypothetical protein 0.0664 0.0769 0.1217
Schistosoma mansoni pyruvate kinase 0.0029 0.0017 0.0019
Brugia malayi G-protein coupled receptor 0.0164 0.0177 0.0177
Giardia lamblia Methyltransferase like 2 0.1345 0.1577 0.941
Echinococcus multilocularis neuropeptide receptor 0.0164 0.0177 0.0218
Loa Loa (eye worm) TK/ALK protein kinase 0.0281 0.0316 0.0356
Schistosoma mansoni smad1 5 8 and 0.0031 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus granulosus pyruvate kinase 0.0029 0.0017 0.0026
Schistosoma mansoni smad1 5 8 and 0.0031 0.0018 0.0021
Brugia malayi Cytochrome P450 family protein 0.0062 0.0055 0.0055
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.006 0.0053 0.006
Brugia malayi N-terminal motif family protein 0.0023 0.0009 0.0009
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0164 0.0177 0.0218
Loa Loa (eye worm) hypothetical protein 0.0264 0.0295 0.0333
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.1121 0.1311 0.1662
Brugia malayi Tnks protein 0.003 0.0018 0.0018
Loa Loa (eye worm) G-protein coupled receptor 0.0164 0.0177 0.0199
Schistosoma mansoni neuropeptide receptor 0.0164 0.0177 0.0202
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0024 0.0134
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0036 0.0061
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0057 0.005 0.0287
Leishmania major hypothetical protein, conserved 0.0327 0.037 0.2196
Plasmodium falciparum protein kinase 7 0.0237 0.0263 0.1989
Echinococcus granulosus tm gpcr rhodopsin 0.0164 0.0177 0.0279
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0146 0.023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0204 0.0224 0.0282
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0451 0.0517 0.0656
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0002 0.0002
Trypanosoma cruzi ISWI complex protein 0.0026 0.0013 0.0064
Trichomonas vaginalis Nicastrin precursor, putative 0.0056 0.0049 0.0288
Onchocerca volvulus Pyruvate kinase homolog 0.0029 0.0017 0.0012
Loa Loa (eye worm) nuclear hormone receptor 0.0046 0.0037 0.0041
Trypanosoma cruzi PAB1-binding protein , putative 0.0327 0.037 0.2196
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.445 0.5259 0.6675
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.002 0.0115
Echinococcus granulosus zinc finger protein 0.0038 0.0027 0.0042
Plasmodium falciparum ataxin-2 like protein, putative 0.0327 0.037 0.2801
Echinococcus granulosus dna polymerase kappa 0.0033 0.0022 0.0034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0166 0.0179 0.0283
Mycobacterium leprae Polyketide synthase Pks13 0.6658 0.7878 1
Schistosoma mansoni acyl carrier protein 0.0451 0.0517 0.0591
Echinococcus granulosus son of sevenless 1 0.0023 0.0009 0.0014
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0048 0.0039 0.0048
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0045 0.0035 0.0042
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0048 0.0039 0.0062
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0032 0.002 0.0023
Schistosoma mansoni hypothetical protein 0.0055 0.0047 0.0054
Mycobacterium leprae conserved hypothetical protein 0.0031 0.0019 0.0024
Leishmania major protein kinase, putative 0.0026 0.0013 0.0066
Brugia malayi EGF-like domain containing protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Trypanosoma brucei glucose transporter 1E 0.0025 0.0011 0.0057
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0046 0.0037 0.0058
Schistosoma mansoni zinc finger protein 0.0038 0.0027 0.003
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0453 0.0519 0.0656
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0226 0.025 0.0285
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.006 0.0053 0.006
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0157 0.0168 0.0265
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.008 0.0077 0.0122
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0064 0.037
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0043 0.0043
Echinococcus multilocularis 0.002 0.0006 0.0007
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0094 0.0094 0.0116
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0024 0.001 0.0016
Brugia malayi putative neuropeptide receptor 0.0164 0.0177 0.0177
Echinococcus multilocularis smad 0.0031 0.0018 0.0022
Echinococcus granulosus g-protein coupled receptor 0.0164 0.0177 0.0279
Mycobacterium tuberculosis Probable lipase LipD 0.0031 0.0019 0.0024
Loa Loa (eye worm) inositol-1 0.0069 0.0064 0.0072
Leishmania major d-xylulose reductase, putative 0.0277 0.0311 0.1846
Leishmania major hypothetical protein, conserved 0.0033 0.0021 0.0112
Giardia lamblia DINP protein human, muc B family 0.0033 0.0022 0.011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0032 0.002 0.002
Brugia malayi Importin beta-1 subunit 0.0036 0.0025 0.0025
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0166 0.0179 0.0202
Echinococcus granulosus MAM 0.0033 0.0022 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0173 0.0213
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0048 0.0039 0.005
Plasmodium falciparum ataxin-2 like protein, putative 0.0327 0.037 0.2801
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0132 0.0139 0.0138
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0022 0.0008 0.0037
Trypanosoma brucei unspecified product 0.0023 0.0009 0.0044
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0277 0.0311 0.1846
Trypanosoma brucei pyruvate kinase 1, putative 0.0029 0.0017 0.0088
Onchocerca volvulus 0.0038 0.0027 0.0023
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0062 0.0055 0.007
Loa Loa (eye worm) pyruvate kinase 0.0029 0.0017 0.0018
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0277 0.0311 0.1846
Echinococcus granulosus neuropeptide receptor 0.0164 0.0177 0.0279
Loa Loa (eye worm) hypothetical protein 0.0379 0.0431 0.0486
Schistosoma mansoni zinc finger protein 0.0046 0.0037 0.0042
Echinococcus granulosus poly (ADP ribose) polymerase 0.0064 0.0058 0.0091
Plasmodium vivax CDK-related protein kinase 6, putative 0.0351 0.0398 0.3021
Schistosoma mansoni z-protein (S1r protein) 0.0032 0.002 0.0023
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0164 0.0177 0.0202
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0098 0.0098 0.011
Brugia malayi Probable isocitrate dehydrogenase 0.0024 0.001 0.001
Loa Loa (eye worm) RasGEF domain-containing protein 0.0023 0.0009 0.001
Giardia lamblia PHD finger protein 15 0.0021 0.0007 0.002
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.1121 0.1311 0.1499
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0033 0.0022 0.0027
Echinococcus granulosus neuropeptides capa receptor 0.0164 0.0177 0.0279
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0164 0.0177 0.0177
Leishmania major pyruvate kinase 0.0029 0.0017 0.0088
Loa Loa (eye worm) hypothetical protein 0.0277 0.0311 0.0351
Trichomonas vaginalis Importin beta-1 subunit, putative 0.003 0.0017 0.0098
Loa Loa (eye worm) hypothetical protein 0.0186 0.0203 0.0229
Trypanosoma brucei unspecified product 0.0033 0.0022 0.0117
Loa Loa (eye worm) glutaminase 2 0.1365 0.1601 0.1806
Entamoeba histolytica hypothetical protein 0.0064 0.0058 0.0325
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0029 0.0017 0.0021
Brugia malayi photoreceptor-specific nuclear receptor 0.0264 0.0295 0.0295
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0164 0.0177 0.0202
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0052 0.0043 0.0049
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0277 0.0311 0.1852
Mycobacterium tuberculosis Conserved protein 0.1345 0.1577 0.2002
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0002 0.0002
Echinococcus granulosus sodium:hydrogen exchanger 0.0038 0.0027 0.0042
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0005 0.0004
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.4727 0.5588 0.7093
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Loa Loa (eye worm) hypothetical protein 0.0132 0.0139 0.0156
Brugia malayi follicle stimulating hormone receptor 0.0366 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.003
Schistosoma mansoni hypothetical protein 0.0078 0.0075 0.0085
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus granulosus muscleblind protein 0.0254 0.0283 0.0448
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0063 0.0372
Onchocerca volvulus 0.0033 0.0022 0.0017
Trichomonas vaginalis penicillin-binding protein, putative 0.0031 0.0019 0.0111
Onchocerca volvulus Tankyrase homolog 0.003 0.0018 0.0014
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Entamoeba histolytica serine/threonine protein kinase, putative 0.1428 0.1676 1
Echinococcus granulosus jumonji domain containing protein 0.0029 0.0016 0.0025
Echinococcus multilocularis Nicastrin 0.0056 0.0049 0.006
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.009 0.0088 0.0139
Echinococcus granulosus serotonin receptor 0.0164 0.0177 0.0279
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0023 0.0009 0.0011
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0106 0.0107 0.0132
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0035 0.0024 0.0156
Echinococcus granulosus cpg binding protein 0.0024 0.0011 0.0017
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0147 0.0156 0.0246
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0277 0.0311 0.0351
Mycobacterium ulcerans polyketide synthase 0.4727 0.5588 0.7093
Schistosoma mansoni hypothetical protein 0.0285 0.032 0.0365
Trichomonas vaginalis glucose transporter, putative 0.0025 0.0011 0.0065
Echinococcus multilocularis adam 0.0047 0.0038 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0019 0.0024
Brugia malayi intracellular kinase 0.0057 0.005 0.005
Plasmodium falciparum protein kinase 6 0.0351 0.0398 0.3021
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0197 0.0215 0.1276
Mycobacterium ulcerans fatty acid synthase Fas 0.1403 0.1645 0.2087
Schistosoma mansoni ap endonuclease 0.0048 0.0039 0.0045
Loa Loa (eye worm) hypothetical protein 0.7488 0.8861 1
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0022 0.0008 0.0036
Loa Loa (eye worm) DIX domain-containing protein 0.0032 0.002 0.0022
Echinococcus multilocularis ecdysone induced protein 78C 0.0098 0.0098 0.0121
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Echinococcus granulosus snurportin 1 0.0389 0.0443 0.07
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.0091 0.0104
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0024 0.0011 0.0013
Echinococcus granulosus g protein coupled receptor 0.0164 0.0177 0.0279
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0016 0.0018
Loa Loa (eye worm) sugar transporter 0.008 0.0077 0.0087
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.003
Schistosoma mansoni chromobox protein 0.0068 0.0063 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Brugia malayi gamma-secretase subunit pen-2 0.0108 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus multilocularis tar DNA binding protein 0.0288 0.0323 0.0399
Entamoeba histolytica tartrate dehydrogenase, putative 0.0024 0.001 0.0043
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Brugia malayi MH1 domain containing protein 0.0017 0.0002 0.0002
Schistosoma mansoni sodium/hydrogen exchanger 2 (nhe2) 0.0038 0.0027 0.0031
Echinococcus granulosus peregrin 0.0028 0.0015 0.0024
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0652 0.0756 0.0788
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.1085 0.1269 0.2268
Schistosoma mansoni transcription factor LCR-F1 0.0212 0.0234 0.0267
Echinococcus multilocularis G-protein coupled receptor, putative 0.0164 0.0177 0.0218
Brugia malayi T-complex protein 1, beta subunit 0.0022 0.0008 0.0008
Brugia malayi PHD-finger family protein 0.0021 0.0007 0.0006
Onchocerca volvulus 0.0032 0.002 0.0016
Leishmania major importin beta-1 subunit, putative 0.003 0.0017 0.009
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0277 0.0311 0.0395
Echinococcus granulosus bloom syndrome protein 0.0017 0.0002 0.0003
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0451 0.0517 0.0638
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0506 0.0582 0.0719
Echinococcus multilocularis sodium:hydrogen exchanger 0.0038 0.0027 0.0033
Brugia malayi Dopamine receptor protein 1 0.0164 0.0177 0.0177
Entamoeba histolytica hypothetical protein 0.003 0.0017 0.0082
Echinococcus multilocularis zinc finger protein 0.0038 0.0027 0.0033
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0271 0.0304 0.0385
Onchocerca volvulus 0.0164 0.0177 0.018
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0037 0.0036
Plasmodium vivax topoisomerase I, putative 0.0171 0.0185 0.1387
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0029 0.0016 0.002
Echinococcus granulosus epidermal growth factor receptor 0.0072 0.0067 0.0106
Mycobacterium ulcerans Type I modular polyketide synthase 0.445 0.5259 0.6675
Plasmodium falciparum T-complex protein 1 subunit beta 0.0022 0.0008 0.0037
Brugia malayi Dopamine receptor protein 2 0.0164 0.0177 0.0177
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0024 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Schistosoma mansoni cytochrome P450 0.0017 0.0002 0.0002
Brugia malayi Melibiase family protein 0.006 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0024 0.0026
Echinococcus multilocularis Niemann Pick C1 protein 0.0189 0.0206 0.0254
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0062 0.0056 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0002 0.0002
Brugia malayi MH2 domain containing protein 0.0031 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0024 0.0134
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0116 0.0119 0.0707
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0038 0.0027 0.0042
Echinococcus granulosus survival motor neuron protein 1 0.0271 0.0303 0.0479
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0164 0.0177 0.0218
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0024 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.011 0.0112 0.0128
Onchocerca volvulus 0.0023 0.0009 0.0004
Echinococcus multilocularis NADH dehydrogenase 0.0451 0.0517 0.0638
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0024 0.0137
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0035 0.0035
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0164 0.0177 0.0202
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0002 0.0002
Mycobacterium leprae Probable oxidireductase 0.0277 0.0311 0.0395
Trichomonas vaginalis sugar transporter, putative 0.0025 0.0011 0.0065
Onchocerca volvulus 0.0055 0.0047 0.0044
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1377 0.1615 0.1822
Schistosoma mansoni hypothetical protein 0.0078 0.0075 0.0085
Echinococcus multilocularis integrin alpha 3 0.0182 0.0198 0.0244
Mycobacterium ulcerans lipoprotein LpqF 0.0271 0.0304 0.0383
Trypanosoma cruzi pyruvate kinase 2, putative 0.0029 0.0017 0.0088
Brugia malayi isocitrate dehydrogenase 0.0197 0.0215 0.0215
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0027 0.0014 0.0071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0043 0.0049
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0019 0.0103
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.7388 0.8742 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0164 0.0177 0.0279
Onchocerca volvulus 0.0277 0.0311 0.0321
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0197 0.0215 0.0246
Brugia malayi serine/threonine-protein kinase plk-2 0.1428 0.1676 0.1676
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0155 0.0177
Brugia malayi Melatonin receptor type 1A 0.0164 0.0177 0.0177
Echinococcus granulosus neuropeptide Y receptor 0.0164 0.0177 0.0279
Schistosoma mansoni dep domain containing protein 0.0032 0.002 0.0023
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0032 0.002 0.0023
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0164 0.0177 0.0279
Mycobacterium tuberculosis Probable hydrolase 0.0031 0.0019 0.0024
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0212 0.0234 0.0369
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0048 0.0039 0.0224
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0022 0.0117
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0037 0.0058
Loa Loa (eye worm) hypothetical protein 0.0254 0.0283 0.0319
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Schistosoma mansoni histamine h1 receptor 0.0164 0.0177 0.0202
Echinococcus granulosus presenilin enhancer 2 0.0108 0.0111 0.0175
Loa Loa (eye worm) hypothetical protein 0.0085 0.0082 0.0093
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0018 0.0003 0.0004
Schistosoma mansoni integrin beta subunit 0.0369 0.0419 0.0479
Trypanosoma brucei importin beta-1 subunit, putative 0.0036 0.0025 0.0139
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0051
Mycobacterium leprae Probable polyketide synthase Pks1 0.4727 0.5588 0.7093
Brugia malayi hypothetical protein 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Brugia malayi RasGEF domain containing protein 0.0023 0.0009 0.0009
Loa Loa (eye worm) neuropeptide F receptor 0.0164 0.0177 0.0199
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0277 0.0311 0.0395
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Toxoplasma gondii HEAT repeat-containing protein 0.0036 0.0025 0.0042
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0038 0.0027 0.0023
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0037 0.0033
Echinococcus multilocularis bloom syndrome protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0427 0.0488 0.055
Onchocerca volvulus 0.0164 0.0177 0.018
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0098 0.0098 0.011
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0024 0.001 0.0011
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0277 0.0311 0.0392
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0098 0.0098 0.0154
Schistosoma mansoni ras GTP exchange factor 0.0023 0.0009 0.001
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0024 0.0011 0.0013
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0068 0.0063 0.0099
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0277 0.0311 0.1846
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0024 0.0027
Echinococcus granulosus biogenic amine 5HT receptor 0.5347 0.6323 1
Schistosoma mansoni methyltransferase-related 0.1345 0.1577 0.1804
Echinococcus multilocularis sodium:hydrogen exchanger 0.0038 0.0027 0.0033
Echinococcus granulosus smad 0.0031 0.0018 0.0029
Leishmania major isocitrate dehydrogenase, putative 0.0024 0.001 0.005
Onchocerca volvulus Protein ultraspiracle homolog 0.0098 0.0098 0.0097
Brugia malayi beta-lactamase family protein 0.0031 0.0019 0.0019
Echinococcus multilocularis G protein coupled receptor 139 0.0164 0.0177 0.0218
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0276 0.0309 0.0348
Toxoplasma gondii type I fatty acid synthase, putative 0.4729 0.559 1
Brugia malayi Pre-SET motif family protein 0.0081 0.0078 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0098 0.0098 0.011
Plasmodium vivax calcium-dependent protein kinase, putative 0.0035 0.0024 0.0156
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0032 0.002 0.002
Mycobacterium ulcerans short-chain dehydrogenase 0.0277 0.0311 0.0392
Trichomonas vaginalis CAMK family protein kinase 0.0711 0.0825 0.4921
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0098 0.0098 0.0121
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0277 0.0311 0.0395
Brugia malayi hypothetical protein 0.0327 0.037 0.0369
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0046 0.0037 0.0045
Schistosoma mansoni tyrosine kinase 0.0157 0.0168 0.0191
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.4328 0.5115 0.6493
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0026 0.0144
Echinococcus multilocularis integrin alpha ps 0.0051 0.0042 0.0052
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0022 0.0008 0.001
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0277 0.0311 0.0392
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Loa Loa (eye worm) steroid hormone receptor 0.0098 0.0098 0.011
Echinococcus multilocularis geminin 0.0732 0.085 0.105
Brugia malayi T-complex protein 1, beta subunit 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0027
Echinococcus multilocularis smoothened 0.0227 0.0251 0.0309
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.1121 0.1311 1
Brugia malayi Furin-like cysteine rich region family protein 0.0072 0.0067 0.0067
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1428 0.1676 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0037
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0164 0.0177 0.0202
Echinococcus multilocularis neuropeptide Y receptor 0.0164 0.0177 0.0218
Brugia malayi G protein-coupled receptor F59B2.13 0.0164 0.0177 0.0177
Plasmodium falciparum calcium-dependent protein kinase 1 0.0035 0.0024 0.0156
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0436 0.0499 0.0498
Trypanosoma brucei ISWI complex protein 0.0026 0.0013 0.0064
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0024 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0045 0.0035 0.0039
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1428 0.1676 0.207
Brugia malayi Dopamine receptor 0.0164 0.0177 0.0177
Echinococcus multilocularis expressed conserved protein 0.0026 0.0013 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0037 0.0042
Brugia malayi G-protein coupled receptor 0.0164 0.0177 0.0177
Onchocerca volvulus 0.0164 0.0177 0.018
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0282 0.0316 0.0316
Plasmodium vivax ataxin-2 like protein, putative 0.0327 0.037 0.2801
Mycobacterium ulcerans thioesterase 0.3721 0.4394 0.5577
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0038 0.0027 0.0023
Brugia malayi EGF-like domain containing protein 0.002 0.0006 0.0006
Echinococcus granulosus GPCR family 2 0.0436 0.0499 0.0788
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0024 0.001 0.0058
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0035 0.0024 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Mycobacterium leprae putative cytochrome p450 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Brugia malayi Bromodomain containing protein 0.0068 0.0063 0.0063
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.1114 0.1304 0.7777
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0277 0.0311 0.1839
Schistosoma mansoni integrin alpha-ps 0.0055 0.0048 0.0054
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Echinococcus granulosus fibrillin 1 0.002 0.0006 0.0009
Echinococcus multilocularis peregrin 0.0028 0.0015 0.0019
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0024 0.0126
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0164 0.0177 0.0279
Echinococcus multilocularis fmrfamide receptor 0.0164 0.0177 0.0218
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0037 0.0026 0.0031
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Echinococcus multilocularis neuropeptide receptor A26 0.0589 0.0681 0.0841
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0048 0.0039 0.0048
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0436 0.0499 0.0788
Echinococcus multilocularis FTZ F1 alpha 0.0098 0.0098 0.0121
Loa Loa (eye worm) hypothetical protein 0.0685 0.0794 0.0896
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0026 0.0144
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0125 0.013 0.0768
Mycobacterium ulcerans hypothetical protein 0.0031 0.0019 0.0022
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0162 0.0174 0.0196
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0389 0.0443 0.0499
Echinococcus granulosus sterol regulatory element binding protein 0.0081 0.0078 0.0123
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0685 0.0794 0.1008
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0069 0.0064 0.0079
Onchocerca volvulus 0.0164 0.0177 0.018
Echinococcus multilocularis neuropeptides capa receptor 0.0164 0.0177 0.0218
Mycobacterium ulcerans hypothetical protein 0.0451 0.0517 0.0654
Brugia malayi exodeoxyribonuclease III family protein 0.0048 0.0039 0.0039
Plasmodium vivax acyl carrier protein, putative 0.0451 0.0517 0.3927
Brugia malayi lysyl-tRNA synthetase 0.0018 0.0003 0.0003
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0046 0.0037 0.0042
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.1091 0.1276 0.1619
Loa Loa (eye worm) hypothetical protein 0.0444 0.0509 0.0574
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0002 0.0003
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0164 0.0177 0.0218
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.1403 0.1645 0.2088
Leishmania major hypothetical protein, conserved 0.0282 0.0316 0.1878
Treponema pallidum exodeoxyribonuclease (exoA) 0.0048 0.0039 0.0156
Echinococcus granulosus somatostatin receptor 0.0164 0.0177 0.0279
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0098 0.0098 0.0097
Loa Loa (eye worm) acyl carrier protein 0.0451 0.0517 0.0583
Loa Loa (eye worm) hypothetical protein 0.3656 0.4317 0.4872
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0031 0.0018 0.0022
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0277 0.0311 0.0491
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0106 0.0107 0.0169
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0024 0.0011 0.0016
Brugia malayi nuclear receptor NHR-88 0.0098 0.0098 0.0098
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0164 0.0177 0.0279
Schistosoma mansoni tankyrase 0.003 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Loa Loa (eye worm) hypothetical protein 0.0062 0.0056 0.0063
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0069 0.0064 0.0378
Echinococcus granulosus gamma secretase subunit aph 1 0.0276 0.0309 0.0488
Loa Loa (eye worm) DR-78 0.0046 0.0037 0.0041
Echinococcus multilocularis survival motor neuron protein 1 0.0271 0.0303 0.0374
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0204 0.0224 0.1329
Loa Loa (eye worm) hypothetical protein 0.0222 0.0245 0.0276
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0164 0.0177 0.0218
Plasmodium falciparum calcium-dependent protein kinase 5 0.0035 0.0024 0.0156
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.445 0.5259 0.6676
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0047 0.0047
Echinococcus granulosus tumor protein p63 0.0261 0.0292 0.0461
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0197 0.0215 0.1623
Schistosoma mansoni topbp1 0.0032 0.002 0.0022
Schistosoma mansoni hypothetical protein 0.0107 0.0109 0.0125
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0023 0.0009 0.001
Toxoplasma gondii hypothetical protein 0.0032 0.002 0.0032
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 1
Leishmania major lysyl-tRNA synthetase, putative 0.0018 0.0003 0.0008
Plasmodium vivax SET domain protein, putative 0.0081 0.0078 0.0572
Echinococcus multilocularis protein patched 0.0081 0.0078 0.0096
Mycobacterium ulcerans acyl carrier protein 0.0451 0.0517 0.0654
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0277 0.0311 0.0392
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0022 0.0117
Loa Loa (eye worm) hypothetical protein 0.0099 0.01 0.0112
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.008 0.0077 0.0122
Toxoplasma gondii lysine-tRNA ligase 0.0018 0.0003 0.0002
Echinococcus multilocularis jumonji domain containing protein 0.0029 0.0016 0.002
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.002 0.0115
Schistosoma mansoni alcohol dehydrogenase 0.0277 0.0311 0.0355
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0088 0.0101
Echinococcus granulosus lysyl tRNA synthetase 0.0018 0.0003 0.0005
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0037 0.0036
Echinococcus multilocularis sterol regulatory element binding protein 0.0081 0.0078 0.0096
Schistosoma mansoni gamma-secretase subunit aph-1 0.0276 0.0309 0.0353
Schistosoma mansoni coup transcription factor 0.0098 0.0098 0.0112
Schistosoma mansoni importin beta-1 0.0036 0.0025 0.0028
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0097 0.0097 0.012
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0024 0.003
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0038 0.0027 0.0033
Schistosoma mansoni dishevelled 0.0032 0.002 0.0023
Trichomonas vaginalis glutaminase, putative 0.1365 0.1601 0.9551
Trypanosoma cruzi hexose transporter, putative 0.0025 0.0011 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.1345 0.1577 0.9411
Brugia malayi MH2 domain containing protein 0.0031 0.0018 0.0018
Echinococcus multilocularis serotonin receptor 0.0427 0.0488 0.0602
Brugia malayi jmjC domain containing protein 0.0068 0.0063 0.0062
Echinococcus granulosus TGF beta signal transducer SmadC 0.0031 0.0018 0.0029
Mycobacterium ulcerans hypothetical protein 0.0045 0.0035 0.0042
Giardia lamblia Tenascin-X 0.002 0.0006 0.0016
Plasmodium vivax glycogen synthase kinase 3, putative 0.0057 0.005 0.0358
Onchocerca volvulus 0.0164 0.0177 0.018
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0098 0.0098 0.0154
Schistosoma mansoni topbp1 0.0032 0.002 0.0022
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0164 0.0177 0.0177
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0277 0.0311 0.0395
Echinococcus granulosus histone lysine methyltransferase setb 0.011 0.0112 0.0177
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.1102 0.1289 0.1455
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0045 0.0035 0.0042
Echinococcus multilocularis isocitrate dehydrogenase 0.0197 0.0215 0.0266
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0022 0.0026
Echinococcus granulosus fibrillin 2 0.002 0.0006 0.0009
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.0173 0.0273
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) MH1 domain-containing protein 0.0031 0.0018 0.002
Mycobacterium leprae conserved hypothetical protein 0.0451 0.0517 0.0656
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Echinococcus granulosus Protein son of sevenless 0.0023 0.0009 0.0014
Brugia malayi Alcohol dehydrogenase class III 0.0277 0.0311 0.0311
Mycobacterium tuberculosis Polyketide synthase Pks2 0.4328 0.5115 0.6493
Brugia malayi Integrin beta pat-3 precursor 0.0626 0.0724 0.0724
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0027 0.0014 0.0081
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0164 0.0177 0.0202
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0022 0.0008 0.0036
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0033 0.0022 0.0125
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0264 0.0296 0.1755
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0098 0.0098 0.0098
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0032 0.002 0.0073
Echinococcus granulosus sodium:hydrogen exchanger 2 (nhe2) 0.0031 0.0018 0.0029
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.152 0.1784 0.2265
Echinococcus multilocularis neuropeptide receptor 0.0164 0.0177 0.0218
Echinococcus granulosus AMP dependent ligase 0.0453 0.0519 0.082
Mycobacterium tuberculosis Conserved hypothetical protein 0.0139 0.0147 0.0187
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Brugia malayi topoisomerase 0.0032 0.002 0.002
Brugia malayi Tachykinin-like peptides receptor 99D 0.0164 0.0177 0.0177
Brugia malayi Presenilin-like protein At2g29900 0.004 0.003 0.003
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.1121 0.1311 0.7821
Loa Loa (eye worm) pyruvate kinase-PB 0.002 0.0006 0.0007
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0277 0.0311 0.1839
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0022 0.0008 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.005 0.028
Mycobacterium ulcerans acyl carrier protein 0.0451 0.0517 0.0654
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0277 0.0311 0.2311
Schistosoma mansoni DNA topoisomerase type I 0.0128 0.0134 0.0153
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.0038 0.0027 0.0027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0164 0.0177 0.0218
Onchocerca volvulus Bile acid receptor homolog 0.0444 0.0509 0.0529
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0197 0.0215 0.1276
Schistosoma mansoni jumonji domain containing protein 0.0054 0.0046 0.0052
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0007 0.0007
Echinococcus multilocularis regulator of G protein signaling 7 0.0032 0.002 0.0024
Echinococcus multilocularis Niemann Pick C1 protein 0.027 0.0302 0.0373
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0007 0.0008
Onchocerca volvulus 0.0031 0.0019 0.0015
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0436 0.0499 0.0788
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0451 0.0517 0.0656
Brugia malayi N-terminal motif family protein 0.0023 0.0009 0.0009
Brugia malayi Pyruvate kinase, M2 isozyme 0.0029 0.0017 0.0016
Mycobacterium ulcerans glutaminase 0.1365 0.1601 0.203
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.4727 0.5588 0.7093
Mycobacterium ulcerans polyketide synthase Pks9 0.2937 0.3465 0.4398
Chlamydia trachomatis pyruvate kinase 0.0029 0.0017 0.0102
Loa Loa (eye worm) G-protein coupled receptor 0.0164 0.0177 0.0199
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0226 0.025 0.148
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.005 0.0295
Mycobacterium tuberculosis Conserved protein 0.0031 0.0019 0.0024
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.445 0.5259 0.5259
Echinococcus multilocularis DNA topoisomerase 1 0.0171 0.0185 0.0228
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0022 0.0024
Echinococcus multilocularis MAM 0.0033 0.0022 0.0026
Schistosoma mansoni tyrosine kinase 0.0072 0.0067 0.0077
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0022 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0204 0.0224 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0018 0.0105
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0019 0.0103
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0293 0.0329 0.195
Leishmania major protein kinase, putative 0.0026 0.0013 0.0066
Schistosoma mansoni patched 1 0.0081 0.0078 0.0089
Entamoeba histolytica hypothetical protein 0.003 0.0018 0.0089
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0098 0.0098 0.0121
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus granulosus Smad4 0.0031 0.0018 0.0029
Trypanosoma cruzi hexose transporter, putative 0.0025 0.0011 0.0057
Schistosoma mansoni DNA topoisomerase type I 0.0171 0.0185 0.0211
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0035 0.0024 0.0023
Loa Loa (eye worm) STE/STE11/ASK protein kinase 0.1114 0.1304 0.1471
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0282 0.0316 0.0399
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1428 0.1676 0.265
Brugia malayi nuclear receptor NHR-88 0.0046 0.0037 0.0036
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0164 0.0177 0.0218
Loa Loa (eye worm) hypothetical protein 0.0036 0.0025 0.0028
Schistosoma mansoni tyrosine kinase 0.0069 0.0064 0.0073
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0024 0.001 0.001
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0069 0.0064 0.0363
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0069 0.0064 0.0111
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0024 0.0011 0.001
Schistosoma mansoni hypothetical protein 0.0056 0.0049 0.0055
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0022 0.0034
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.008 0.0077 0.0095
Echinococcus multilocularis allatostatin A receptor 0.0164 0.0177 0.0218
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0027 0.0144
Schistosoma mansoni neuropeptide F-like receptor 0.0164 0.0177 0.0202
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0024 0.0126
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0002 0.0002
Brugia malayi MH2 domain containing protein 0.0451 0.0516 0.0516
Echinococcus multilocularis sodium and chloride dependent glycine 0.0062 0.0056 0.0069
Echinococcus granulosus G protein coupled receptor 139 0.0164 0.0177 0.0279
Brugia malayi Presenilin family protein 0.0116 0.0119 0.0119
Echinococcus granulosus Protein patched homolog 1 0.0081 0.0078 0.0123
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0022 0.0024
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0026 0.0013 0.0016
Echinococcus granulosus poly adp ribose polymerase 2 0.0226 0.025 0.0394
Brugia malayi Pre-SET motif family protein 0.0562 0.0648 0.0648
Mycobacterium tuberculosis Probable esterase LipL 0.0031 0.0019 0.0024
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.1085 0.1269 0.1611
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.3208 0.3786 0.4806
Leishmania major phosphopantetheinyl transferase-like protein 0.0037 0.0026 0.0144
Brugia malayi Probable isocitrate dehydrogenase 0.0024 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0081
Brugia malayi hypothetical protein 0.0027 0.0014 0.0014
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.0116 0.0119 0.0136
Schistosoma mansoni hypothetical protein 0.0078 0.0075 0.0085
Onchocerca volvulus 0.0164 0.0177 0.018
Schistosoma mansoni hypothetical protein 0.0164 0.0177 0.0202
Schistosoma mansoni amine GPCR 0.0164 0.0177 0.0202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0098 0.0098 0.011
Brugia malayi MH1 domain containing protein 0.0031 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0057 0.005 0.0056
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0277 0.0311 0.0395
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0048 0.0039 0.0224
Echinococcus granulosus DNA topoisomerase 1 0.0171 0.0185 0.0291
Echinococcus granulosus fmrfamide receptor 0.0164 0.0177 0.0279
Trypanosoma cruzi acyl transferase-like protein, putative 0.0282 0.0316 0.1878
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0038 0.0027 0.0042
Loa Loa (eye worm) pyruvate kinase 0.0029 0.0017 0.0018
Brugia malayi Protein kinase domain containing protein 0.0157 0.0168 0.0167
Brugia malayi Cam kinase protein 1 0.0035 0.0024 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0009 0.0044
Schistosoma mansoni hypothetical protein 0.0436 0.0499 0.057
Loa Loa (eye worm) nuclear factor I 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0271 0.0303 0.0341
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.006 0.0053 0.0312
Trichomonas vaginalis importin beta-1, putative 0.003 0.0017 0.0098
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0045 0.0035 0.0042
Schistosoma mansoni alpha-1 adrenergic receptor 0.0164 0.0177 0.0202
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.002 0.0107
Brugia malayi hypothetical protein 0.0032 0.002 0.002
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0019 0.0111
Echinococcus granulosus neuropeptide s receptor 0.0589 0.0681 0.1076
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0031 0.0019 0.0024
Schistosoma mansoni cellular tumor antigen P53 0.0038 0.0027 0.0031
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Schistosoma mansoni hypothetical protein 0.0078 0.0075 0.0085
Giardia lamblia hypothetical protein 0.002 0.0006 0.0016
Echinococcus granulosus presenilin 0.0116 0.0119 0.0188
Echinococcus granulosus regulator of G protein signaling 7 0.0032 0.002 0.0031
Brugia malayi hypothetical protein 0.0056 0.0049 0.0049
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.3636 0.4294 0.5451
Toxoplasma gondii aldehyde dehydrogenase 0.0204 0.0224 0.0398
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0024 0.0011 0.0059
Trypanosoma brucei DNA polymerase eta, putative 0.0033 0.0022 0.0117
Mycobacterium tuberculosis Polyketide synthase Pks12 0.4727 0.5588 0.7093
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0002 0.0002
Leishmania major glucose transporter/membrane transporter D2, putative 0.0025 0.0011 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0562 0.0648 0.0731
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.1121 0.1311 1
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0074 0.0069 0.0079
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.008 0.0077 0.0095
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0037 0.0042
Echinococcus multilocularis biogenic amine (5HT) receptor 0.5347 0.6323 0.7812
Leishmania major pyruvate kinase 0.0029 0.0017 0.0088
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0037 0.0026 0.0031
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0197 0.0215 0.1276
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0166 0.0179 0.0179
Schistosoma mansoni glucose transport protein 0.008 0.0077 0.0088
Schistosoma mansoni [ACP] S-malonyltransferase 0.0282 0.0316 0.0361
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0464 0.0532 0.0676
Echinococcus granulosus mothers against decapentaplegic 5 0.0031 0.0018 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0288 0.0323 0.0369
Trichomonas vaginalis sugar transporter, putative 0.0025 0.0011 0.0065
Leishmania major zinc-binding dehydrogenase-like protein 0.0277 0.0311 0.1846
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0037 0.0026 0.0174
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0451 0.0517 0.0656
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0204 0.0224 0.0277
Mycobacterium ulcerans Type I modular polyketide synthase 0.445 0.5259 0.6675
Echinococcus granulosus dna polymerase eta 0.0033 0.0022 0.0034
Loa Loa (eye worm) neuropeptide F receptor 0.0164 0.0177 0.0199
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Echinococcus multilocularis chromobox protein 1 0.0068 0.0063 0.0077
Giardia lamblia Tenascin-like 0.002 0.0006 0.0016
Schistosoma mansoni tyrosine kinase 0.0069 0.0064 0.0073
Echinococcus multilocularis somatostatin receptor 0.0164 0.0177 0.0218
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0054 0.0085
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0037 0.0026 0.0043
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0064 0.037
Mycobacterium ulcerans oxidoreductase 0.0277 0.0311 0.0392
Loa Loa (eye worm) hypothetical protein 0.0277 0.0311 0.0351
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0204 0.0224 0.0285
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0164 0.0177 0.0202
Trypanosoma brucei THT1 - hexose transporter, putative 0.0025 0.0011 0.0057
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0031 0.018
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0035 0.0035
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.002 0.0115
Onchocerca volvulus 0.0164 0.0177 0.018
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0057 0.005 0.0086
Mycobacterium ulcerans thioesterase TesA 0.3721 0.4394 0.5577
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.0038 0.0027 0.0042
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0685 0.0794 0.1008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.1121 0.1311 0.7821
Echinococcus multilocularis mothers against decapentaplegic 5 0.0031 0.0018 0.0022
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0022 0.0021
Loa Loa (eye worm) sodium/hydrogen exchanger 0.0038 0.0027 0.003
Brugia malayi GnHR receptor homolog 0.0164 0.0177 0.0177
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0277 0.0311 0.0395
Echinococcus granulosus acyl carrier protein mitochondrial 0.0451 0.0517 0.0817
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Echinococcus granulosus alpha 1A adrenergic receptor 0.0164 0.0177 0.0279
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0453 0.0519 0.0656
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0098 0.0098 0.011
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.1121 0.1311 0.1479
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0451 0.0517 0.3894
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0098 0.0098 0.0112
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0164 0.0177 0.0218
Echinococcus granulosus integrin alpha ps 0.0051 0.0042 0.0067
Schistosoma mansoni kinase 0.073 0.0847 0.0969
Onchocerca volvulus 0.0132 0.0139 0.014
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0098 0.0098 0.0112
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.002 0.0005 0.0019
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0277 0.0311 0.0384
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Brugia malayi nuclear hormone receptor family member odr-7 0.0046 0.0037 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0036 0.0252
Trypanosoma brucei RNA helicase, putative 0.0107 0.0109 0.0641
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0018 0.0003 0.0008
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0212 0.0234 0.0289
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0054 0.0066
Schistosoma mansoni growth hormone secretagogue receptor 0.0164 0.0177 0.0202
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0032 0.002 0.0016
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.002 0.0005 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0002 0.0002
Leishmania major quinone oxidoreductase, putative 0.0277 0.0311 0.1846
Echinococcus granulosus nicalin 0.0021 0.0007 0.001
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0035 0.0024 0.0039
Plasmodium falciparum acyl carrier protein 0.0451 0.0517 0.3927
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0065
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0277 0.0311 0.0392
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trichomonas vaginalis ras GTP exchange factor, putative 0.0023 0.0009 0.0051
Plasmodium falciparum proline--tRNA ligase 0.0028 0.0015 0.0092
Schistosoma mansoni tyrosine kinase 0.0072 0.0067 0.0077
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0147 0.0156 0.0192
Schistosoma mansoni hypothetical protein 0.008 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0436 0.0499 0.0562
Schistosoma mansoni neuropeptide receptor 0.0164 0.0177 0.0202
Entamoeba histolytica protein kinase, putative 0.0035 0.0024 0.0122
Toxoplasma gondii type I fatty acid synthase, putative 0.3178 0.3751 0.6709
Trypanosoma brucei Nicastrin, putative 0.0021 0.0007 0.0027
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Trichomonas vaginalis pyruvate kinase, putative 0.0029 0.0017 0.0096
Loa Loa (eye worm) hypothetical protein 0.0226 0.025 0.0281
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.1085 0.1269 0.9677
Onchocerca volvulus Alhambra homolog 0.0021 0.0007 0.0002
Trichomonas vaginalis ras GTP exchange factor, putative 0.0023 0.0009 0.0051
Toxoplasma gondii histone lysine methyltransferase SET1 0.0048 0.0039 0.0067
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0098 0.0098 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Echinococcus granulosus tankyrase 0.003 0.0018 0.0028
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.002 0.0115
Echinococcus granulosus WGR domain containing protein 0.0128 0.0133 0.021
Brugia malayi G protein-coupled receptor 0.0164 0.0177 0.0177
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0048 0.0039 0.0277
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0023 0.0009 0.001
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0277 0.0311 0.0392
Brugia malayi hypothetical protein 0.0211 0.0232 0.0232
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0023 0.0009 0.0004
Loa Loa (eye worm) cytochrome P450 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0164 0.0177 0.0202
Entamoeba histolytica hypothetical protein 0.0212 0.0234 0.1379
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0018 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0027 0.0031
Trichomonas vaginalis Nicastrin precursor, putative 0.0056 0.0049 0.0288
Onchocerca volvulus 0.0031 0.0019 0.0015
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0277 0.0311 0.1839
Echinococcus granulosus inositol monophosphatase 1 0.0069 0.0064 0.0101
Leishmania major DNA polymerase eta, putative 0.0033 0.0022 0.0117
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0164 0.0177 0.0202
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Loa Loa (eye worm) hypothetical protein 0.0189 0.0206 0.0232
Onchocerca volvulus 0.0164 0.0177 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0009 0.0044
Onchocerca volvulus 0.0092 0.0091 0.009
Echinococcus multilocularis protein kinase shaggy 0.0057 0.005 0.0061
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0023 0.0009 0.0051
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0032 0.002 0.0024
Schistosoma mansoni RAR-like nuclear receptor 0.0098 0.0098 0.0112
Brugia malayi beta-lactamase 0.0031 0.0019 0.0019
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0024 0.0027
Brugia malayi hypothetical protein 0.0164 0.0177 0.0177
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0098 0.0098 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.1428 0.1676 1
Brugia malayi Smad1 0.0031 0.0018 0.0018
Brugia malayi TAR-binding protein 0.0288 0.0323 0.0323
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0132 0.0139 0.0158
Echinococcus multilocularis sodium and chloride dependent glycine 0.0062 0.0056 0.0069
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.009 0.0088 0.0109
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Echinococcus multilocularis sex peptide receptor 0.0164 0.0177 0.0218
Plasmodium vivax hypothetical protein, conserved 0.064 0.0741 0.5641
Brugia malayi Isocitrate dehydrogenase 0.0197 0.0215 0.0215
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0032 0.002 0.01
Loa Loa (eye worm) hypothetical protein 0.011 0.0112 0.0126
Loa Loa (eye worm) Smad1 0.0031 0.0018 0.002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0098 0.0098 0.0098
Mycobacterium ulcerans polyketide synthase MbtD 0.1373 0.161 0.2042
Brugia malayi hypothetical protein 0.0271 0.0303 0.0303
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0035 0.0042
Brugia malayi beta-lactamase family protein 0.0031 0.0019 0.0019
Mycobacterium ulcerans quinone oxidoreductase 0.0277 0.0311 0.0392
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0095 0.0095 0.0107
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0026 0.0013 0.0016
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0164 0.0177 0.0279
Loa Loa (eye worm) hypothetical protein 0.0098 0.0098 0.011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0166 0.0179 0.0221
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0277 0.0311 0.1846
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0045 0.0035 0.0044
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Loa Loa (eye worm) RecQ helicase 0.0017 0.0002 0.0002
Schistosoma mansoni nuclear receptor 0.0046 0.0037 0.0042
Echinococcus granulosus integrin beta 2 0.0464 0.0532 0.0841
Loa Loa (eye worm) hypothetical protein 0.0065 0.0059 0.0066
Echinococcus granulosus neuropeptides capa receptor 0.0164 0.0177 0.0279
Schistosoma mansoni DNA ligase IV 0.0032 0.002 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0052 0.0043 0.0048
Toxoplasma gondii DNA topoisomerase I, putative 0.0171 0.0185 0.0327
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0024
Mycobacterium ulcerans DNA polymerase IV 0.0033 0.0022 0.0025
Loa Loa (eye worm) RNA binding protein 0.0288 0.0323 0.0364
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.1121 0.1311 0.1662
Echinococcus granulosus tar DNA binding protein 0.0288 0.0323 0.051
Schistosoma mansoni unc-13 (munc13) 0.0024 0.001 0.0012
Schistosoma mansoni hypothetical protein 0.0436 0.0499 0.057
Mycobacterium tuberculosis Possible dehydrogenase 0.0277 0.0311 0.0395
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0177 0.0218
Trypanosoma cruzi hexose transporter, putative 0.0025 0.0011 0.0057
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0037 0.0033
Echinococcus multilocularis fibrillin 2 0.002 0.0006 0.0007
Schistosoma mansoni methyl-cpg binding protein mbd 0.0029 0.0016 0.0018
Toxoplasma gondii t-complex protein beta subunit 0.0022 0.0008 0.0011
Trypanosoma brucei poly(adp-ribose) polymerase 0.0226 0.025 0.148
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0098 0.0098 0.0154
Echinococcus multilocularis dna polymerase eta 0.0033 0.0022 0.0026
Echinococcus granulosus adam 0.0047 0.0038 0.0059
Loa Loa (eye worm) presenilin spe-4 0.004 0.003 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0427 0.0488 0.055
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0027 0.0014 0.0071
Leishmania major glucose transporter, lmgt2 0.0025 0.0011 0.0057
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.008 0.0077 0.0122
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0035 0.0024 0.0026
Entamoeba histolytica hypothetical protein 0.0023 0.0009 0.0035
Loa Loa (eye worm) hypothetical protein 0.0254 0.0283 0.0319
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0045 0.0035 0.0042
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.005 0.028
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Schistosoma mansoni hypothetical protein 0.0147 0.0156 0.0178
Loa Loa (eye worm) acetyltransferase 0.0146 0.0155 0.0175
Echinococcus granulosus adam 17 protease 0.017 0.0184 0.029
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0077 0.0073 0.0082
Loa Loa (eye worm) MH2 domain-containing protein 0.0031 0.0018 0.002
Echinococcus multilocularis pyruvate kinase 0.0029 0.0017 0.002
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0325 0.0367 0.0654
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0027 0.0014 0.0014
Echinococcus multilocularis snurportin 1 0.0389 0.0443 0.0547
Schistosoma mansoni DNA polymerase eta 0.0033 0.0022 0.0024
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0029
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0022 0.0117
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0052 0.0043 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0019 0.0111
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0033 0.0022 0.0117
Echinococcus multilocularis g protein coupled receptor 0.0164 0.0177 0.0218
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0032 0.002 0.002
Loa Loa (eye worm) nuclear receptor NHR-67 0.0046 0.0037 0.0041
Brugia malayi Nuclear hormone receptor-like 1 0.0098 0.0098 0.0098
Echinococcus granulosus smoothened 0.0227 0.0251 0.0396
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.014 0.0148 0.0262
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0007 0.0026
Echinococcus multilocularis GPCR, family 2 0.0436 0.0499 0.0616
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.1121 0.1311 0.162
Schistosoma mansoni microtubule-associated protein tau 0.2455 0.2893 0.331
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0277 0.0311 0.1852
Brugia malayi Integrin alpha pat-2 precursor 0.0237 0.0263 0.0263
Schistosoma mansoni alpha-glucosidase 0.0139 0.0146 0.0167
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0023 0.0009 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Trypanosoma brucei glucose transporter, putative 0.0025 0.0011 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Loa Loa (eye worm) hypothetical protein 0.1377 0.1615 0.1822
Schistosoma mansoni chromosome transmission fidelity factor 0.0032 0.002 0.0022
Echinococcus multilocularis pyruvate kinase 0.0023 0.0009 0.0011
Schistosoma mansoni hypothetical protein 0.0212 0.0234 0.0267
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0031 0.0019 0.0022
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0062 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0941 0.1098 0.1239
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0197 0.0215 0.0266
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.2539 0.2992 0.3798
Trichomonas vaginalis set domain proteins, putative 0.0639 0.074 0.4414
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.002 0.0005 0.0019
Giardia lamblia Prolyl-tRNA synthetase 0.0024 0.0011 0.0044
Entamoeba histolytica hypothetical protein 0.0212 0.0234 0.1379
Brugia malayi Bromodomain containing protein 0.0028 0.0015 0.0015
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0048 0.0039 0.0224
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0035 0.0024 0.0026
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Trichomonas vaginalis D-aminoacylase, putative 0.0031 0.0019 0.0111
Echinococcus multilocularis inositol monophosphatase 1 0.0069 0.0064 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0177 0.0279
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0031 0.0019 0.0022
Echinococcus granulosus tachykinin peptides receptor 99D 0.0164 0.0177 0.0279
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0125 0.013 0.0768
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0045 0.0035 0.0044
Brugia malayi Cytochrome P450 family protein 0.0017 0.0002 0.0002
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0026 0.0033
Toxoplasma gondii hypothetical protein 0.0043 0.0033 0.0055
Loa Loa (eye worm) hypothetical protein 0.0086 0.0084 0.0095
Brugia malayi MH1 domain containing protein 0.0017 0.0002 0.0002
Mycobacterium leprae Probable lipase LipE 0.0031 0.0019 0.0024
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0277 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0048
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.011 0.0112 0.0138
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0011
Echinococcus granulosus tm gpcr rhodopsin 0.0506 0.0582 0.092
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.064 0.0741 0.5641
Schistosoma mansoni sodium/chloride dependent transporter 0.0074 0.007 0.008
Schistosoma mansoni zinc binding dehydrogenase 0.0277 0.0311 0.0355
Trypanosoma cruzi acyl transferase-like protein 0.0282 0.0316 0.1878
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Trypanosoma brucei PAB1-binding protein , putative 0.0327 0.037 0.2196
Brugia malayi RNA, U transporter 1 0.0104 0.0105 0.0104
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.0038 0.0027 0.0023
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0464 0.0532 0.0676
Echinococcus multilocularis Smad4 0.0031 0.0018 0.0022
Leishmania major mitochondrial DNA polymerase beta 0.0264 0.0296 0.1755
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0037
Echinococcus multilocularis dro:myosuppressin receptor 0.0164 0.0177 0.0218
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0036 0.0057
Leishmania major DNA topoisomerase IB, large subunit 0.0128 0.0134 0.0787
Brugia malayi Calcitonin receptor-like protein seb-1 0.1377 0.1615 0.1614
Brugia malayi Steroid receptor seven-up type 2 0.0098 0.0098 0.0098
Trypanosoma brucei pyruvate kinase 1 0.0029 0.0017 0.0088
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0164 0.0177 0.0202
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0164 0.0177 0.0202
Leishmania major DNA topoisomerase type IB small subunit 0.0043 0.0033 0.0185
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0097 0.0097 0.0153
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0045 0.0035 0.0044
Loa Loa (eye worm) hypothetical protein 0.006 0.0053 0.0059
Brugia malayi jmjC domain containing protein 0.003 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0024 0.0134
Leishmania major DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0037 0.0058
Schistosoma mansoni protein kinase 0.0035 0.0024 0.0027
Plasmodium falciparum topoisomerase I 0.0171 0.0185 0.1387
Trichomonas vaginalis ap endonuclease, putative 0.0048 0.0039 0.0232
Echinococcus multilocularis Nicastrin 0.0056 0.0049 0.006
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0277 0.0311 0.0392
Brugia malayi tailless protein 0.0046 0.0037 0.0036
Mycobacterium tuberculosis Possible penicillin-binding protein 0.02 0.0219 0.0279
Brugia malayi regulator of G-protein signaling egl-10 0.0032 0.002 0.002
Mycobacterium tuberculosis Possible dehydrogenase 0.0277 0.0311 0.0395
Mycobacterium tuberculosis Conserved hypothetical protein 0.0451 0.0517 0.0656
Loa Loa (eye worm) gamma-secretase subunit pen-2 0.0108 0.0111 0.0125
Brugia malayi ORL1-like opioid receptor 0.0164 0.0177 0.0177
Echinococcus granulosus beta LACTamase domain containing family member 0.0031 0.0019 0.003
Leishmania major T-complex protein 1, beta subunit, putative 0.0022 0.0008 0.0036
Trypanosoma brucei DNA repair protein, putative 0.002 0.0005 0.0019
Loa Loa (eye worm) CXXC zinc finger family protein 0.002 0.0006 0.0006
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0164 0.0177 0.0218
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0069 0.0064 0.0378
Giardia lamblia Sodium/hydrogen exchanger 3 0.0038 0.0027 0.0142
Brugia malayi PHD-finger family protein 0.0047 0.0037 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0081
Brugia malayi Latrophilin receptor protein 2 0.0436 0.0499 0.0498
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0155 0.0165 0.0189
Echinococcus multilocularis integrin beta 2 0.0464 0.0532 0.0657
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.002 0.0107
Schistosoma mansoni alpha glucosidase 0.0036 0.0024 0.0028
Schistosoma mansoni regulator of G protein signaling 0.0032 0.002 0.0023
Echinococcus multilocularis nicalin 0.0021 0.0007 0.0008
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0164 0.0177 0.0202
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.3577 0.4224 0.5362
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0073 0.0069 0.0068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0166 0.0179 0.0205
Loa Loa (eye worm) hypothetical protein 0.0179 0.0195 0.022
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0024 0.0011 0.001
Toxoplasma gondii hypothetical protein 0.0033 0.0021 0.0034
Schistosoma mansoni biogenic amine (5HT) receptor 0.0427 0.0488 0.0558
Brugia malayi glutaminase DH11.1 0.1365 0.1601 0.16
Echinococcus multilocularis tumor protein p63 0.0261 0.0292 0.036
Leishmania major 4-coumarate:coa ligase-like protein 0.0045 0.0035 0.0196
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0107
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0023 0.0009 0.0014
Loa Loa (eye worm) fatty acid synthase 0.4406 0.5206 0.5875
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0098 0.0098 0.0098
Trypanosoma cruzi Nicastrin, putative 0.0021 0.0007 0.0027
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0164 0.0177 0.0218
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0035 0.0035
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0031 0.0018 0.0022
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.0173 0.0173
Echinococcus granulosus tm gpcr rhodopsin 0.0764 0.0888 0.1404
Onchocerca volvulus 0.0277 0.0311 0.0321
Schistosoma mansoni myosin xvIII 0.0164 0.0177 0.0202
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0177 0.0202
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0451 0.0517 0.0583
Trypanosoma brucei beta lactamase 0.0271 0.0304 0.1802
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0037 0.0045
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0073 0.0069 0.0108
Brugia malayi neuropeptide F receptor 0.0164 0.0177 0.0177
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0037 0.0026 0.0144
Echinococcus granulosus regulator of G protein signaling 7 0.0032 0.002 0.0031
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0022 0.0117
Echinococcus granulosus thyroid hormone receptor alpha 0.0046 0.0037 0.0058
Brugia malayi DKFZp564C0469 protein 0.0032 0.002 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0464 0.0532 0.0673
Entamoeba histolytica hypothetical protein 0.0212 0.0234 0.1379
Toxoplasma gondii ATPase, AAA family protein 0.0032 0.002 0.0032
Echinococcus multilocularis presenilin 0.0116 0.0119 0.0147
Leishmania major oxidoreductase, putative 0.0277 0.0311 0.1846
Entamoeba histolytica hypothetical protein 0.003 0.0018 0.0089
Echinococcus multilocularis beta LACTamase domain containing family member 0.0031 0.0019 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0166 0.0179 0.0283
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0464 0.0532 0.0532
Trichomonas vaginalis sugar transporter, putative 0.0025 0.0011 0.0065
Schistosoma mansoni inositol monophosphatase 0.0069 0.0064 0.0073
Loa Loa (eye worm) hypothetical protein 0.0164 0.0177 0.0199
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.3721 0.4394 0.5578
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0436 0.0499 0.0616
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0029
Schistosoma mansoni [ACP] S-malonyltransferase 0.0282 0.0316 0.0361
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.0043 0.0033 0.0185
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0037 0.0058
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.2937 0.3465 0.4398
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0023 0.0009 0.001
Giardia lamblia High cysteine protein 0.002 0.0006 0.0016
Brugia malayi Methyltransferase-like protein 4 0.1345 0.1577 0.1577
Brugia malayi hypothetical protein 0.004 0.003 0.003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.009 0.0088 0.0101
Schistosoma mansoni hypothetical protein 0.0026 0.0013 0.0014
Trypanosoma cruzi pyruvate kinase 2, putative 0.0029 0.0017 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Echinococcus multilocularis son of sevenless 1 0.0023 0.0009 0.0011
Onchocerca volvulus Pyruvate kinase homolog 0.0029 0.0017 0.0012
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0464 0.0532 0.0673
Giardia lamblia TCP-1 chaperonin subunit beta 0.0022 0.0008 0.0029
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0464 0.0532 0.0676
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0453 0.0519 0.0659
Echinococcus granulosus cGMP dependent protein kinase 1 0.0026 0.0013 0.002
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Schistosoma mansoni smad1 5 8 and 0.0031 0.0018 0.0021
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0008 0.0009
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0226 0.025 0.0308
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0078 0.0074 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0166 0.0179 0.0205
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0098 0.0098 0.0154
Onchocerca volvulus 0.0032 0.002 0.0016
Schistosoma mansoni protein kinase 0.3668 0.4331 0.4954
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0277 0.0311 0.0395
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0035 0.0024 0.0039
Loa Loa (eye worm) hypothetical protein 0.0072 0.0068 0.0076
Loa Loa (eye worm) AGC/PKG protein kinase 0.0026 0.0013 0.0014
Schistosoma mansoni hypothetical protein 0.0941 0.1098 0.1256
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0037 0.0026 0.0144
Trypanosoma brucei glucosidase, putative 0.0036 0.0024 0.0134
Brugia malayi hypothetical protein 0.0052 0.0043 0.0043
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0116 0.0119 0.0707
Mycobacterium ulcerans pyruvate kinase 0.0029 0.0017 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0078 0.0462
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.002 0.0107
Loa Loa (eye worm) hypothetical protein 0.0379 0.0431 0.0486
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.684 0.8093 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0197 0.0215 0.1276
Loa Loa (eye worm) hypothetical protein 0.0046 0.0037 0.0041
Brugia malayi Serotonin receptor 0.0498 0.0572 0.0572
Toxoplasma gondii LsmAD domain-containing protein 0.0327 0.037 0.0658
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0013 0.0015
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.0173 0.0195
Plasmodium vivax importin-beta 2, putative 0.0036 0.0025 0.0168
Trichomonas vaginalis DNA helicase recq1, putative 0.0017 0.0002 0.001
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0028 0.0015 0.008
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0164 0.0177 0.0279
Entamoeba histolytica protein kinase, putative 0.0035 0.0024 0.0122
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0026 0.0144
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0464 0.0532 0.0676
Echinococcus granulosus L aminoadipate semialdehyde 0.0132 0.0139 0.0219
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0024 0.0037
Trypanosoma cruzi DNA polymerase kappa, putative 0.0033 0.0022 0.0117
Schistosoma mansoni hypothetical protein 0.0436 0.0499 0.057
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0098 0.0098 0.0112
Echinococcus granulosus nuclear receptor nhr 48 0.0046 0.0037 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0009 0.0044
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0023 0.0009 0.0035
Leishmania major hypothetical protein, conserved 0.0026 0.0013 0.0064
Loa Loa (eye worm) RasGEF domain-containing protein 0.0023 0.0009 0.001
Echinococcus granulosus pyruvate kinase 0.0029 0.0017 0.0026
Plasmodium falciparum replication factor C subunit 1, putative 0.0032 0.002 0.0127
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.1121 0.1311 0.7821
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0192 0.0209 0.0239

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.747 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.715 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.702 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.682 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.498 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.476 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.466 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.434 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.387 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.005 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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