Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.006 | 0.0174 | 0.0174 |
Trichomonas vaginalis | cyclin B, putative | 0.0593 | 0.2944 | 0.2915 |
Echinococcus granulosus | cyclins | 0.0247 | 0.1148 | 0.1137 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0026 | 0 | 0.5 |
Leishmania major | mitotic cyclin, putative | 0.006 | 0.0174 | 0.0174 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.006 | 0.0174 | 0.0174 |
Echinococcus granulosus | mitogen activated protein kinase | 0.1952 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1952 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0247 | 0.1148 | 0.1137 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0819 | 0.4117 | 0.4117 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.1952 | 1 | 1 |
Echinococcus multilocularis | cyclins | 0.0247 | 0.1148 | 0.1137 |
Onchocerca volvulus | 0.0593 | 0.2944 | 1 | |
Echinococcus multilocularis | cyclin G2 | 0.006 | 0.0174 | 0.0162 |
Trichomonas vaginalis | cyclin A, putative | 0.006 | 0.0174 | 0.0133 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.006 | 0.0174 | 0.0174 |
Trichomonas vaginalis | cyclin B, putative | 0.006 | 0.0174 | 0.0133 |
Schistosoma mansoni | cyclin G2 | 0.006 | 0.0174 | 0.0149 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.1952 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.006 | 0.0174 | 0.0174 |
Trichomonas vaginalis | cyclin B3, putative | 0.0247 | 0.1148 | 0.1111 |
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.006 | 0.0174 | 0.0162 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0247 | 0.1148 | 0.1148 |
Leishmania major | mitotic cyclin, putative | 0.006 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.1952 | 1 | 1 |
Schistosoma mansoni | cyclin B | 0.0593 | 0.2944 | 0.2926 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.006 | 0.0174 | 0.0162 |
Loa Loa (eye worm) | CYL-1 protein | 0.006 | 0.0174 | 0.0174 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0819 | 0.4117 | 0.4102 |
Toxoplasma gondii | cyclin, N-terminal domain-containing protein | 0.006 | 0.0174 | 0.0149 |
Schistosoma mansoni | cyclin k | 0.006 | 0.0174 | 0.0149 |
Echinococcus multilocularis | cyclins | 0.0247 | 0.1148 | 0.1137 |
Trichomonas vaginalis | cyclin B, putative | 0.0593 | 0.2944 | 0.2915 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.1952 | 1 | 1 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.006 | 0.0174 | 0.0174 |
Entamoeba histolytica | cyclin family protein | 0.0247 | 0.1148 | 0.247 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0247 | 0.1148 | 0.1137 |
Echinococcus granulosus | Cyclin L1 | 0.006 | 0.0174 | 0.0162 |
Entamoeba histolytica | cyclin, putative | 0.0247 | 0.1148 | 0.247 |
Schistosoma mansoni | cyclin l | 0.006 | 0.0174 | 0.0149 |
Echinococcus multilocularis | cdk5 and abl1 enzyme substrate 1 | 0.006 | 0.0174 | 0.0162 |
Echinococcus multilocularis | cyclins | 0.0247 | 0.1148 | 0.1137 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0036 | 0.0054 | 0.0054 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.0031 | 0.0025 | 0.0013 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0819 | 0.4117 | 0.4093 |
Trypanosoma brucei | cyclin 9 | 0.006 | 0.0174 | 0.0174 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.0071 | 0.0046 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0055 | 0.0151 | 0.0151 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0036 | 0.0054 | 0.0054 |
Trichomonas vaginalis | conserved hypothetical protein | 0.006 | 0.0174 | 0.0133 |
Echinococcus granulosus | cyclin G2 | 0.006 | 0.0174 | 0.0162 |
Loa Loa (eye worm) | AGC/PKG protein kinase | 0.0031 | 0.0025 | 0.0025 |
Echinococcus multilocularis | cyclin B | 0.0593 | 0.2944 | 0.2935 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.006 | 0.0174 | 0.0174 |
Brugia malayi | Protein kinase domain containing protein | 0.0819 | 0.4117 | 0.4117 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0819 | 0.4117 | 0.4102 |
Trypanosoma cruzi | cyclin 9, putative | 0.006 | 0.0174 | 0.0174 |
Trichomonas vaginalis | conserved hypothetical protein | 0.006 | 0.0174 | 0.0133 |
Plasmodium falciparum | cyclin | 0.0247 | 0.1148 | 0.2744 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1952 | 1 | 1 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0819 | 0.4117 | 0.4117 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.006 | 0.0174 | 0.0174 |
Toxoplasma gondii | cyclin domain protein, cyclin H family protein | 0.006 | 0.0174 | 0.0149 |
Trichomonas vaginalis | cyclin B, putative | 0.0593 | 0.2944 | 0.2915 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0819 | 0.4117 | 0.411 |
Trichomonas vaginalis | conserved hypothetical protein | 0.006 | 0.0174 | 0.0133 |
Brugia malayi | hypothetical protein | 0.006 | 0.0174 | 0.0174 |
Echinococcus granulosus | cyclin A3 4 | 0.006 | 0.0174 | 0.0162 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0819 | 0.4117 | 1 |
Entamoeba histolytica | cyclin family protein | 0.0247 | 0.1148 | 0.247 |
Loa Loa (eye worm) | hypothetical protein | 0.0593 | 0.2944 | 0.2944 |
Schistosoma mansoni | cyclin B3 | 0.0247 | 0.1148 | 0.1126 |
Trichomonas vaginalis | cyclin A, putative | 0.0593 | 0.2944 | 0.2915 |
Brugia malayi | cyclin fold protein 1 variant b | 0.006 | 0.0174 | 0.0174 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.0071 | 0.0046 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.1952 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.1952 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0029 | 0.0029 |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.0031 | 0.0025 | 0.0013 |
Brugia malayi | Cyclin C | 0.006 | 0.0174 | 0.0174 |
Trichomonas vaginalis | cyclins, putative | 0.0593 | 0.2944 | 0.2915 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0593 | 0.2944 | 0.2944 |
Brugia malayi | hypothetical protein | 0.006 | 0.0174 | 0.0174 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.1952 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0174 | 0.0149 |
Echinococcus multilocularis | cyclin y | 0.006 | 0.0174 | 0.0162 |
Trypanosoma brucei | cyclin 3 | 0.006 | 0.0174 | 0.0174 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0247 | 0.1148 | 0.1111 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0593 | 0.2944 | 0.2944 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0593 | 0.2944 | 0.2944 |
Trichomonas vaginalis | cyclin D, putative | 0.0247 | 0.1148 | 0.1111 |
Giardia lamblia | Kinase, CMGC CDK | 0.0819 | 0.4117 | 0.4013 |
Trichomonas vaginalis | cyclins, putative | 0.0593 | 0.2944 | 0.2915 |
Echinococcus multilocularis | cyclin G2 | 0.006 | 0.0174 | 0.0162 |
Schistosoma mansoni | cyclin d | 0.006 | 0.0174 | 0.0149 |
Trypanosoma cruzi | cyclin, putative | 0.0593 | 0.2944 | 0.2944 |
Echinococcus multilocularis | Cyclin L1 | 0.006 | 0.0174 | 0.0162 |
Toxoplasma gondii | cyclin 4, putative | 0.006 | 0.0174 | 0.0149 |
Trichomonas vaginalis | cyclin B3, putative | 0.006 | 0.0174 | 0.0133 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0819 | 0.4117 | 0.411 |
Echinococcus granulosus | cyclins | 0.0247 | 0.1148 | 0.1137 |
Echinococcus multilocularis | cyclin t1 | 0.006 | 0.0174 | 0.0162 |
Toxoplasma gondii | hypothetical protein | 0.006 | 0.0174 | 0.0149 |
Trichomonas vaginalis | cyclin B, putative | 0.0247 | 0.1148 | 0.1111 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.006 | 0.0174 | 0.0162 |
Trichomonas vaginalis | cyclins, putative | 0.006 | 0.0174 | 0.0133 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.1952 | 1 | 1 |
Schistosoma mansoni | cyclin G | 0.006 | 0.0174 | 0.0149 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0819 | 0.4117 | 0.4117 |
Leishmania major | protein kinase, putative | 0.0031 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0174 | 0.0174 |
Echinococcus multilocularis | cyclin B3 1 | 0.0247 | 0.1148 | 0.1137 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1952 | 1 | 1 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0247 | 0.1148 | 0.1137 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0819 | 0.4117 | 0.411 |
Echinococcus multilocularis | cyclin A3 4 | 0.006 | 0.0174 | 0.0162 |
Trichomonas vaginalis | cyclin D, putative | 0.0247 | 0.1148 | 0.1111 |
Echinococcus multilocularis | cyclins | 0.0247 | 0.1148 | 0.1137 |
Plasmodium falciparum | cyclin 1 | 0.006 | 0.0174 | 0.0364 |
Schistosoma mansoni | cyclins | 0.0247 | 0.1148 | 0.1126 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0819 | 0.4117 | 0.4117 |
Brugia malayi | Cytochrome P450 family protein | 0.0055 | 0.0151 | 0.0151 |
Echinococcus granulosus | cyclins | 0.0247 | 0.1148 | 0.1137 |
Echinococcus granulosus | cGMP dependent protein kinase | 0.0031 | 0.0025 | 0.0013 |
Brugia malayi | Egg laying defective protein 4 | 0.0031 | 0.0025 | 0.0025 |
Echinococcus granulosus | cyclin k | 0.006 | 0.0174 | 0.0162 |
Leishmania major | cyclin 9, putative | 0.006 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0819 | 0.4117 | 0.4117 |
Echinococcus granulosus | cyclin | 0.006 | 0.0174 | 0.0162 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0819 | 0.4117 | 0.4117 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0036 | 0.0054 | 0.0041 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.006 | 0.0174 | 0.0364 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.0031 | 0.0025 | 0.0013 |
Echinococcus multilocularis | expressed conserved protein | 0.0031 | 0.0025 | 0.0013 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.1952 | 1 | 1 |
Schistosoma mansoni | Cyclin fold protein | 0.006 | 0.0174 | 0.0149 |
Giardia lamblia | Hypothetical protein | 0.0247 | 0.1148 | 0.0991 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0819 | 0.4117 | 0.4093 |
Echinococcus granulosus | cyclins | 0.0247 | 0.1148 | 0.1137 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0819 | 0.4117 | 0.4117 |
Giardia lamblia | Kinase, CMGC MAPK | 0.1952 | 1 | 1 |
Loa Loa (eye worm) | cyclin fold protein 1 variant b | 0.006 | 0.0174 | 0.0174 |
Echinococcus granulosus | cyclin dependent kinase | 0.0819 | 0.4117 | 0.411 |
Echinococcus granulosus | cyclin B | 0.0593 | 0.2944 | 0.2935 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0036 | 0.0054 | 0.0041 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.006 | 0.0174 | 0.0174 |
Trichomonas vaginalis | cyclin B3, putative | 0.006 | 0.0174 | 0.0133 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0819 | 0.4117 | 0.411 |
Trichomonas vaginalis | cyclins, putative | 0.0593 | 0.2944 | 0.2915 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0247 | 0.1148 | 0.1148 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0819 | 0.4117 | 0.4117 |
Echinococcus granulosus | cyclin t1 | 0.006 | 0.0174 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0346 | 0.166 | 0.166 |
Plasmodium falciparum | cyclin dependent kinase binding protein, putative | 0.006 | 0.0174 | 0.0364 |
Toxoplasma gondii | cyclin dependent kinase binding protein | 0.006 | 0.0174 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0793 | 0.3981 | 0.3981 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0593 | 0.2944 | 0.2944 |
Echinococcus granulosus | cyclins | 0.0247 | 0.1148 | 0.1137 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.1952 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1952 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0188 | 0.0838 | 0.0815 |
Echinococcus granulosus | cyclin G2 | 0.006 | 0.0174 | 0.0162 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0819 | 0.4117 | 0.4102 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.006 | 0.0174 | 0.0174 |
Trichomonas vaginalis | cyclins, putative | 0.006 | 0.0174 | 0.0133 |
Loa Loa (eye worm) | cyclin C | 0.006 | 0.0174 | 0.0174 |
Trypanosoma brucei | STE group serine/threonine-protein kinase, putative | 0.0029 | 0.0017 | 0.0017 |
Trichomonas vaginalis | cyclins, putative | 0.0593 | 0.2944 | 0.2915 |
Loa Loa (eye worm) | hypothetical protein | 0.0593 | 0.2944 | 0.2944 |
Echinococcus multilocularis | cyclin k | 0.006 | 0.0174 | 0.0162 |
Echinococcus multilocularis | cyclin b3 | 0.0247 | 0.1148 | 0.1137 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.006 | 0.0174 | 0.0149 |
Brugia malayi | cell division control protein 2 homolog | 0.0819 | 0.4117 | 0.4117 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1952 | 1 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.006 | 0.0174 | 0.0174 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.006 | 0.0174 | 0.0174 |
Echinococcus granulosus | cdk5 and abl1 enzyme substrate 1 | 0.006 | 0.0174 | 0.0162 |
Entamoeba histolytica | cyclin, putative | 0.0593 | 0.2944 | 0.7025 |
Echinococcus granulosus | cyclin y | 0.006 | 0.0174 | 0.0162 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0819 | 0.4117 | 0.411 |
Plasmodium falciparum | protein kinase 5 | 0.0819 | 0.4117 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.006 | 0.0174 | 0.0133 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1952 | 1 | 1 |
Echinococcus granulosus | cyclins | 0.006 | 0.0174 | 0.0162 |
Trypanosoma brucei | cyclin dependent kinase-binding protein, putative | 0.006 | 0.0174 | 0.0174 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.006 | 0.0174 | 0.0162 |
Trichomonas vaginalis | cyclin B, putative | 0.006 | 0.0174 | 0.0133 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1952 | 1 | 1 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0593 | 0.2944 | 0.2944 |
Leishmania major | cyclin | 0.0593 | 0.2944 | 0.2944 |
Echinococcus granulosus | cyclin y | 0.006 | 0.0174 | 0.0162 |
Trypanosoma cruzi | cyclin 6, putative | 0.0593 | 0.2944 | 0.2944 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0174 | 0.0149 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0819 | 0.4117 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0819 | 0.4117 | 0.4093 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0174 | 0.0174 |
Plasmodium vivax | protein kinase Crk2 | 0.0819 | 0.4117 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0593 | 0.2944 | 0.2944 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.006 | 0.0174 | 0.0174 |
Echinococcus multilocularis | cyclin y | 0.006 | 0.0174 | 0.0162 |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.0031 | 0.0025 | 0.0013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.006 | 0.0174 | 0.0133 |
Trichomonas vaginalis | cyclins, putative | 0.0247 | 0.1148 | 0.1111 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0819 | 0.4117 | 0.4117 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.006 | 0.0174 | 0.0174 |
Trypanosoma brucei | protein kinase, putative | 0.1952 | 1 | 1 |
Echinococcus granulosus | cyclin B3 1 | 0.0247 | 0.1148 | 0.1137 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.006 | 0.0174 | 0.0174 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0819 | 0.4117 | 0.411 |
Echinococcus multilocularis | cyclins | 0.0247 | 0.1148 | 0.1137 |
Trypanosoma brucei | mitotic cyclin | 0.006 | 0.0174 | 0.0174 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0593 | 0.2944 | 0.2819 |
Trichomonas vaginalis | cyclins, putative | 0.0406 | 0.197 | 0.1937 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0819 | 0.4117 | 0.411 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0819 | 0.4117 | 0.4117 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.006 | 0.0174 | 0.0174 |
Leishmania major | protein kinase, putative | 0.0031 | 0.0025 | 0.0025 |
Giardia lamblia | Cyclin A | 0.0247 | 0.1148 | 0.0991 |
Echinococcus multilocularis | cyclin | 0.006 | 0.0174 | 0.0162 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0819 | 0.4117 | 0.4117 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.006 | 0.0174 | 0.0149 |
Echinococcus granulosus | cyclin b3 | 0.0247 | 0.1148 | 0.1137 |
Trichomonas vaginalis | cyclin B, putative | 0.0593 | 0.2944 | 0.2915 |
Echinococcus multilocularis | cyclins | 0.0247 | 0.1148 | 0.1137 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.006 | 0.0174 | 0.0174 |
Giardia lamblia | Kinase, CMGC CDK | 0.0819 | 0.4117 | 0.4013 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -7.281 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.617 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.425 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.142 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.998 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.969 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.231 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.222 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.163 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.