Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | heat shock protein 90 | 0.0043 | 0.1188 | 0.1764 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0017 | 0.0202 | 0.0251 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.019 | 0.0283 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Trypanosoma brucei | heat shock protein 90, putative | 0.005 | 0.147 | 0.4103 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0018 | 0.0216 | 0.0534 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Loa Loa (eye worm) | RecQ helicase | 0.0026 | 0.0541 | 0.0514 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0034 | 0.0829 | 0.2278 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0042 | 0.1162 | 0.3157 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0284 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1466 | 0.2178 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0033 | 0.0815 | 0.121 |
Trypanosoma brucei | heat shock protein, putative | 0.005 | 0.147 | 0.4103 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0117 | 0.4111 | 0.8844 |
Brugia malayi | Hsp90 protein | 0.0033 | 0.0815 | 0.0788 |
Plasmodium falciparum | glutathione reductase | 0.0018 | 0.0216 | 0.0273 |
Mycobacterium ulcerans | glucose-6-phosphate 1-dehydrogenase | 0.0102 | 0.3489 | 1 |
Toxoplasma gondii | heat shock protein 90, putative | 0.005 | 0.147 | 0.2093 |
Toxoplasma gondii | ubiquitin carboxyl-terminal hydrolase UCHL3 | 0.0034 | 0.0829 | 0.1162 |
Schistosoma mansoni | heat shock protein | 0.005 | 0.147 | 0.2183 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.005 | 0.147 | 0.4103 |
Schistosoma mansoni | heat shock protein | 0.0033 | 0.0815 | 0.121 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0191 | 0.0463 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0592 | 0.0565 |
Plasmodium vivax | ubiquitin C-terminal hydrolase, family 1, putative | 0.0089 | 0.3002 | 0.4319 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.105 | 0.156 |
Loa Loa (eye worm) | glucose-6-phosphate dehydrogenase | 0.0102 | 0.3489 | 0.347 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0211 | 0.0183 |
Trichomonas vaginalis | Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase | 0.0034 | 0.0829 | 0.2022 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.1162 | 0.3227 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.019 | 0.0283 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.019 | 0.0283 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Treponema pallidum | heat shock protein 90 | 0.0047 | 0.135 | 0.3463 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0189 | 0.6913 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 0.6733 | 1 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0284 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0041 | 0.1113 | 0.3088 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0033 | 0.0815 | 0.2238 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0163 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0052 | 0.1532 | 0.2275 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase isozyme | 0.0034 | 0.0829 | 0.1231 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0042 | 0.1162 | 0.3227 |
Entamoeba histolytica | heat shock protein 90, putative | 0.005 | 0.147 | 0.4042 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0236 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0051 | 0.151 | 0.3825 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.105 | 0.156 |
Trichomonas vaginalis | Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase | 0.0034 | 0.0829 | 0.2022 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.019 | 0.0283 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0103 | 0.3541 | 0.3522 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0042 | 0.1162 | 0.3275 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Leishmania major | trypanothione reductase | 0.0052 | 0.1532 | 0.428 |
Entamoeba histolytica | heat shock protein 90, putative | 0.005 | 0.147 | 0.4042 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0041 | 0.1113 | 0.1576 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.019 | 0.0283 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.105 | 0.2836 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trichomonas vaginalis | glucosamine-6-phosphate isomerase, putative | 0.0111 | 0.3842 | 1 |
Echinococcus multilocularis | endoplasmin | 0.0047 | 0.135 | 0.2005 |
Schistosoma mansoni | glucose-6-phosphate 1-dehydrogenase | 0.0102 | 0.3489 | 0.5182 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.007 | 0.2247 | 0.2224 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.013 | 0.4602 | 0.4586 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0047 | 0.135 | 0.3818 |
Schistosoma mansoni | ubiquitinyl hydrolase-UCH37 (C12 family) | 0.0089 | 0.3002 | 0.4459 |
Brugia malayi | Endoplasmin precursor | 0.005 | 0.147 | 0.1445 |
Plasmodium falciparum | glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | 0.0111 | 0.3842 | 0.554 |
Chlamydia trachomatis | glucose-6-phosphate 1-dehydrogenase | 0.0102 | 0.3489 | 1 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trichomonas vaginalis | heat shock protein, putative | 0.0036 | 0.0935 | 0.2303 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Trypanosoma brucei | heat shock protein, putative | 0.005 | 0.147 | 0.4103 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1466 | 0.2178 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.019 | 0.0283 |
Treponema pallidum | glucose-6-phosphate 1-dehydrogenase | 0.0102 | 0.3489 | 1 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0034 | 0.0829 | 0.2278 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0103 | 0.3541 | 1 |
Trypanosoma cruzi | heat shock protein, putative | 0.0033 | 0.0815 | 0.2238 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0652 | 0.1775 |
Echinococcus multilocularis | glucose 6 phosphate 1 dehydrogenase | 0.0102 | 0.3489 | 0.5182 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.005 | 0.147 | 0.4103 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0018 | 0.0216 | 0.0056 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0033 | 0.0815 | 0.121 |
Echinococcus granulosus | endoplasmin | 0.0047 | 0.135 | 0.2005 |
Schistosoma mansoni | kinase | 0.0052 | 0.1563 | 0.2321 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0042 | 0.1162 | 0.1726 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0018 | 0.0216 | 0.0542 |
Trichomonas vaginalis | endoplasmin, putative | 0.0036 | 0.0935 | 0.2303 |
Plasmodium vivax | endoplasmin, putative | 0.005 | 0.147 | 0.2093 |
Plasmodium falciparum | glutathione reductase | 0.0052 | 0.1532 | 0.2184 |
Echinococcus multilocularis | dna polymerase kappa | 0.0042 | 0.1162 | 0.1726 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1466 | 0.2178 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 1 | 1 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0089 | 0.3002 | 0.8467 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.005 | 0.147 | 0.3778 |
Trichomonas vaginalis | heat shock protein, putative | 0.0043 | 0.1188 | 0.2973 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.3541 | 0.9201 |
Plasmodium falciparum | heat shock protein 90 | 0.005 | 0.147 | 0.2093 |
Trypanosoma brucei | heat shock protein, putative | 0.005 | 0.147 | 0.4103 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0103 | 0.3541 | 0.5258 |
Plasmodium falciparum | endoplasmin, putative | 0.0036 | 0.0935 | 0.1316 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase isozyme | 0.0089 | 0.3002 | 0.4459 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0047 | 0.135 | 0.3762 |
Loa Loa (eye worm) | ubiquitin C-terminal hydrolase UCH-L5 | 0.0089 | 0.3002 | 0.2982 |
Toxoplasma gondii | thioredoxin reductase | 0.0052 | 0.1532 | 0.2184 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0042 | 0.1162 | 0.219 |
Schistosoma mansoni | ubiquitinyl hydrolase-BAP1 (C12 family) | 0.0034 | 0.0829 | 0.1231 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0163 |
Brugia malayi | glucose-6-phosphate dehydrogenase | 0.0102 | 0.3489 | 0.347 |
Echinococcus multilocularis | bloom syndrome protein | 0.0026 | 0.0541 | 0.0803 |
Giardia lamblia | Glucose-6-phosphate 1-dehydrogenase | 0.0111 | 0.3842 | 1 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0026 | 0.0541 | 0.126 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.1641 | 0.1617 |
Echinococcus multilocularis | heat shock protein 90 | 0.005 | 0.147 | 0.2183 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0026 | 0.0541 | 0.0514 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0018 | 0.0216 | 0.0321 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.1162 | 0.3227 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.1466 | 0.1442 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0236 |
Echinococcus multilocularis | heat shock protein 90 | 0.0043 | 0.1188 | 0.1764 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0592 | 0.1604 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.005 | 0.147 | 0.4103 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0043 | 0.1188 | 0.1764 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0042 | 0.1162 | 0.2905 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0018 | 0.0216 | 0.0273 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.019 | 0.0283 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.1162 | 0.3227 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0216 | 0.0534 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0117 | 0.4111 | 0.8844 |
Echinococcus granulosus | heat shock protein | 0.005 | 0.147 | 0.2183 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0023 | 0.0417 | 0.0564 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.019 | 0.0283 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0103 | 0.3541 | 0.5258 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase, family 1 protein | 0.0034 | 0.0829 | 0.0802 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.019 | 0.0162 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.3541 | 0.9201 |
Trichomonas vaginalis | heat shock protein, putative | 0.005 | 0.147 | 0.3719 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.105 | 0.2836 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0042 | 0.1162 | 0.1726 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0029 | 0.0653 | 0.0907 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.097 | 0.0944 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0017 | 0.0191 | 0.0236 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0042 | 0.1162 | 0.1726 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0013 | 0.0031 | 0.0002 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0131 | 0.4624 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0013 | 0.0031 | 0.0002 |
Trypanosoma cruzi | glucose-6-phosphate 1-dehydrogenase, putative | 0.0102 | 0.3489 | 0.9853 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1466 | 0.2178 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.1466 | 0.1442 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Echinococcus granulosus | heat shock protein 90 | 0.005 | 0.147 | 0.2183 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.1641 | 0.1617 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0018 | 0.0216 | 0.0401 |
Trypanosoma brucei | polo-like protein kinase | 0.0103 | 0.3541 | 1 |
Leishmania major | glucose-6-phosphate 1-dehydrogenase, putative | 0.0102 | 0.3489 | 0.9853 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0017 | 0.0191 | 0.0463 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Plasmodium vivax | glutathione reductase, putative | 0.0052 | 0.1532 | 0.2184 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0117 | 0.4111 | 0.8844 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.105 | 0.2836 |
Plasmodium falciparum | thioredoxin reductase | 0.0052 | 0.1532 | 0.2184 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0103 | 0.3541 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0592 | 0.1604 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0117 | 0.4111 | 0.8844 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0018 | 0.0216 | 0.0534 |
Trypanosoma brucei | heat shock protein, putative | 0.005 | 0.147 | 0.4103 |
Schistosoma mansoni | family C12 unassigned peptidase (C12 family) | 0.0034 | 0.0829 | 0.1231 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0592 | 0.0818 |
Brugia malayi | hypothetical protein | 0.0039 | 0.105 | 0.1025 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0047 | 0.135 | 1 |
Trypanosoma brucei | glucose-6-phosphate 1-dehydrogenase | 0.0102 | 0.3489 | 0.9853 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0052 | 0.1532 | 0.3025 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0052 | 0.1532 | 0.2184 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0018 | 0.0216 | 0.0273 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.019 | 0.0162 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0043 | 0.1188 | 0.33 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0033 | 0.0815 | 0.1142 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0042 | 0.1162 | 0.2905 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.2247 | 0.2224 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.1162 | 0.3227 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0051 | 0.151 | 0.3825 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase BAP1 | 0.0034 | 0.0829 | 0.1231 |
Leishmania major | ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative | 0.0089 | 0.3002 | 0.8467 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0117 | 0.4111 | 0.8844 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1466 | 0.2178 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.005 | 0.147 | 0.4103 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.0111 | 0.3842 | 0.554 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase isozyme | 0.0034 | 0.0829 | 0.1231 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0018 | 0.0216 | 0.0273 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0216 | 0.0188 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0065 | 0.0102 |
Plasmodium vivax | heat shock protein 90, putative | 0.0033 | 0.0815 | 0.1142 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.3541 | 0.9201 |
Mycobacterium tuberculosis | Probable reductase | 0.0117 | 0.4111 | 0.8844 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.0191 | 0.0284 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.019 | 0.0283 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.105 | 0.156 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0065 | 0.0102 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.0829 | 0.2198 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0013 | 0.0029 | 0.0043 |
Brugia malayi | ubiquitin C-terminal hydrolase UCH-L5 | 0.0089 | 0.3002 | 0.2982 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0052 | 0.1532 | 0.2275 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0043 | 0.1188 | 0.3039 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0026 | 0.0541 | 0.126 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0829 | 0.0802 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.5952 | 0.5941 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1641 | 0.1617 |
Plasmodium falciparum | ubiquitin carboxyl-terminal hydrolase isozyme L3 | 0.0034 | 0.0829 | 0.1162 |
Echinococcus granulosus | dna polymerase eta | 0.007 | 0.2247 | 0.3337 |
Onchocerca volvulus | 0.0165 | 0.5952 | 1 | |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0018 | 0.0216 | 0.0534 |
Plasmodium vivax | ubiquitin carboxyl-terminal hydrolase isozyme L3, putative | 0.0034 | 0.0829 | 0.1162 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 0.6733 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0163 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0042 | 0.1162 | 0.219 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Echinococcus multilocularis | heat shock protein | 0.005 | 0.147 | 0.2183 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase isozyme | 0.0089 | 0.3002 | 0.4459 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.105 | 0.2836 |
Trypanosoma brucei | heat shock protein 90, putative | 0.005 | 0.147 | 0.4103 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0047 | 0.135 | 0.2614 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0117 | 0.4111 | 0.8435 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0284 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0216 | 0.0534 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0017 | 0.0191 | 0.0236 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0042 | 0.1162 | 0.3275 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0592 | 0.1604 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0103 | 0.3541 | 1 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.005 | 0.147 | 0.4103 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0089 | 0.3002 | 0.8467 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0131 | 0.4624 | 1 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0034 | 0.0829 | 0.2278 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0042 | 0.1162 | 0.1137 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0021 | 0.0326 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0592 | 0.0565 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase isozyme | 0.0089 | 0.3002 | 0.4459 |
Echinococcus granulosus | dna polymerase kappa | 0.0042 | 0.1162 | 0.1726 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.3541 | 0.9201 |
Plasmodium falciparum | thioredoxin reductase | 0.0018 | 0.0216 | 0.0273 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.105 | 0.156 |
Toxoplasma gondii | heat shock protein HSP90 | 0.005 | 0.147 | 0.2093 |
Plasmodium vivax | glucose-6-phosphate 1-dehydrogenase, putative | 0.0111 | 0.3842 | 0.554 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.007 | 0.2247 | 0.6316 |
Schistosoma mansoni | ubiquitinyl hydrolase-UCH37 (C12 family) | 0.0089 | 0.3002 | 0.4459 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.097 | 0.144 |
Giardia lamblia | Kinase, PLK | 0.0103 | 0.3541 | 0.9208 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0189 | 0.6913 | 1 |
Trichomonas vaginalis | glucosamine-6-phosphate isomerase, putative | 0.0111 | 0.3842 | 1 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.0066 | 0.2112 | 0.3026 |
Brugia malayi | hypothetical protein | 0.0165 | 0.5952 | 0.5941 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.097 | 0.0944 |
Echinococcus multilocularis | dna polymerase eta | 0.007 | 0.2247 | 0.3337 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0131 | 0.4624 | 1 |
Plasmodium falciparum | deubiquinating/deneddylating enzyme | 0.0089 | 0.3002 | 0.4319 |
Trypanosoma brucei | heat shock protein, putative | 0.005 | 0.147 | 0.4103 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0131 | 0.4624 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0029 | 0.0653 | 0.1557 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0592 | 0.0818 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.4664 | 0.4648 |
Leishmania major | DNA polymerase eta, putative | 0.0041 | 0.1113 | 0.3088 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0018 | 0.0216 | 0.0273 |
Echinococcus granulosus | geminin | 0.0185 | 0.6733 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0018 | 0.0216 | 0.0534 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0065 | 0.0102 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0103 | 0.3541 | 0.5305 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1466 | 0.2178 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0018 | 0.021 | 0.0263 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0103 | 0.3541 | 0.5258 |
Brugia malayi | glutathione reductase | 0.0052 | 0.1532 | 0.1508 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0191 | 0.0463 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0052 | 0.1532 | 0.428 |
Echinococcus granulosus | bloom syndrome protein | 0.0026 | 0.0541 | 0.0803 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0033 | 0.0815 | 0.2158 |
Schistosoma mansoni | heat shock protein | 0.005 | 0.147 | 0.2183 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.1641 | 0.1617 |
Loa Loa (eye worm) | glutathione reductase | 0.0052 | 0.1532 | 0.1508 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0592 | 0.0818 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.007 | 0.2247 | 0.6316 |
Schistosoma mansoni | family C12 unassigned peptidase (C12 family) | 0.0034 | 0.0829 | 0.1231 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0017 | 0.0191 | 0.0463 |
Brugia malayi | MH2 domain containing protein | 0.013 | 0.4602 | 0.4586 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0018 | 0.0216 | 0.0321 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0033 | 0.0815 | 0.0788 |
Leishmania major | ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative | 0.0034 | 0.0829 | 0.2278 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.013 | 0.4602 | 0.4586 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.005 | 0.147 | 0.4103 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase BAP1 | 0.0034 | 0.0829 | 0.1231 |
Mycobacterium ulcerans | glucose-6-phosphate 1-dehydrogenase | 0.0066 | 0.2112 | 0.602 |
Mycobacterium tuberculosis | Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) | 0.0035 | 0.0896 | 0.159 |
Schistosoma mansoni | endoplasmin | 0.005 | 0.147 | 0.2183 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0103 | 0.3541 | 0.3522 |
Trypanosoma brucei | unspecified product | 0.0029 | 0.0652 | 0.1775 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0042 | 0.1162 | 0.1137 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0284 |
Loa Loa (eye worm) | heat shock protein 90 | 0.005 | 0.147 | 0.1445 |
Trypanosoma brucei | heat shock protein, putative | 0.005 | 0.147 | 0.4103 |
Trypanosoma brucei | unspecified product | 0.0029 | 0.0652 | 0.1775 |
Brugia malayi | Thioredoxin reductase | 0.0052 | 0.1532 | 0.1508 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0018 | 0.0216 | 0.0401 |
Schistosoma mansoni | family C12 unassigned peptidase (C12 family) | 0.0034 | 0.0829 | 0.1231 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1466 | 0.2178 |
Echinococcus multilocularis | geminin | 0.0185 | 0.6733 | 1 |
Echinococcus granulosus | glucose 6 phosphate 1 dehydrogenase | 0.0102 | 0.3489 | 0.5182 |
Leishmania major | heat shock protein, putative | 0.0033 | 0.0815 | 0.2238 |
Brugia malayi | heat shock protein 90 | 0.005 | 0.147 | 0.1445 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0652 | 0.1775 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0592 | 0.0818 |
Leishmania major | DNA polymerase kappa, putative | 0.0042 | 0.1162 | 0.3227 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0018 | 0.0216 | 0.0542 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.3541 | 0.9201 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trypanosoma brucei | heat shock protein, putative | 0.005 | 0.147 | 0.4103 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0018 | 0.0216 | 0.0492 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0592 | 0.1604 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0018 | 0.0216 | 0.0542 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0042 | 0.1162 | 0.1726 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0018 | 0.0216 | 0.0273 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Schistosoma mansoni | endoplasmin | 0.005 | 0.147 | 0.2183 |
Trichomonas vaginalis | 6-phosphogluconolactonase, putative | 0.0111 | 0.3842 | 1 |
Trypanosoma cruzi | glucose-6-phosphate 1-dehydrogenase, putative | 0.0034 | 0.0834 | 0.2294 |
Loa Loa (eye worm) | endoplasmin | 0.005 | 0.147 | 0.1445 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0018 | 0.0216 | 0.0534 |
Leishmania major | heat shock protein 83-1 | 0.005 | 0.147 | 0.4103 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.3541 | 0.9201 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0018 | 0.0216 | 0.0273 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.019 | 0.0283 |
Plasmodium vivax | heat shock protein 86, putative | 0.005 | 0.147 | 0.2093 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0284 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0052 | 0.1532 | 0.1508 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.3541 | 0.9201 |
Trypanosoma cruzi | Glucose-6-phosphate dehydrogenase, putative | 0.0033 | 0.0796 | 0.2185 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.019 | 0.0162 |
Schistosoma mansoni | DNA polymerase eta | 0.007 | 0.2247 | 0.3337 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0018 | 0.0216 | 0.0321 |
Trichomonas vaginalis | heat shock protein, putative | 0.0047 | 0.135 | 0.3402 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0021 | 0.0335 | 0.0874 |
Toxoplasma gondii | ubiquitin carboxyl-terminal hydrolase, family 1 protein | 0.0089 | 0.3002 | 0.4319 |
Giardia lamblia | Grp94/Hsp90 | 0.0047 | 0.135 | 0.3464 |
Trichomonas vaginalis | heat shock protein, putative | 0.0047 | 0.135 | 0.3402 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0216 | 0.0534 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0103 | 0.3541 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0042 | 0.1162 | 0.2972 |
Trypanosoma brucei | heat shock protein, putative | 0.005 | 0.147 | 0.4103 |
Plasmodium vivax | heat shock protein, putative | 0.0189 | 0.6913 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0043 | 0.1188 | 0.33 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0191 | 0.0463 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0029 | 0.0652 | 0.1775 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase, putative | 0.0089 | 0.3002 | 0.8451 |
Leishmania major | DNA polymerase eta, putative | 0.007 | 0.2247 | 0.6316 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0191 | 0.0284 |
Trypanosoma brucei | trypanothione reductase | 0.0052 | 0.1532 | 0.428 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.019 | 0.0162 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -6.245 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.665 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.987 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.884 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.868 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.839 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.744 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.686 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.673 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.626 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.522 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.