Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.1108 | 0.3187 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.1493 | 0.3843 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0092 | 0.0006 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0092 | 0.0265 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1883 | 0.5428 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0092 | 0.0265 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0092 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1643 | 0.4724 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.1883 | 0.5414 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.176 | 0.506 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0529 | 0.1526 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0032 | 0.1062 | 1 |
Echinococcus granulosus | expressed protein | 0.0033 | 0.1108 | 0.3196 |
Brugia malayi | Bromodomain containing protein | 0.0077 | 0.3739 | 1 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.1108 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0412 | 0.0329 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2127 | 0.5581 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0092 | 0.0265 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0193 | 0.0558 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0092 | 0.0264 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1883 | 0.5428 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0032 | 0.1062 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0092 | 0.0006 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0193 | 0.0108 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.2803 | 0.8083 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.2803 | 0.8083 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2127 | 0.6118 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0073 | 0.3468 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2127 | 0.6118 |
Schistosoma mansoni | rotamase | 0.0033 | 0.1108 | 0.1031 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1883 | 0.1812 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0033 | 0.1108 | 0.2787 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0348 | 0.1003 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.1062 | 1 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0348 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1498 | 0.4307 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0412 | 0.1186 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0092 | 0.0264 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.1349 | 0.3889 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0092 | 0.0265 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1185 | 0.1109 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0193 | 0.0108 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0348 | 0.1003 |
Echinococcus multilocularis | expressed protein | 0.0033 | 0.1108 | 0.3196 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0018 | 0.0193 | 0.0558 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1883 | 0.1812 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0231 | 0.0664 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0032 | 0.1062 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1185 | 0.2998 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1883 | 0.5428 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0092 | 0.0265 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.1883 | 0.4909 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.1349 | 0.3889 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1883 | 0.5428 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0092 | 0.0006 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1883 | 0.1812 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0674 | 0.1596 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0529 | 0.1526 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0193 | 0.0108 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.1108 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2127 | 0.5581 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1185 | 0.3408 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.3478 | 1 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0018 | 0.0193 | 0.0558 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.1062 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.3022 | 0.2962 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0092 | 0.0265 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0073 | 0.3468 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0193 | 0.0556 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0193 | 0.0558 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0529 | 0.0447 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0032 | 0.1062 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0193 | 0.0108 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.