Detailed information for compound 1652849

Basic information

Technical information
  • TDR Targets ID: 1652849
  • Name: (2R)-2-amino-3-prop-2-enylsulfanylpropanoic a cid
  • MW: 161.222 | Formula: C6H11NO2S
  • H donors: 2 H acceptors: 2 LogP: -2.07 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N[C@H](C(=O)O)CSCC=C
  • InChi: 1S/C6H11NO2S/c1-2-3-10-4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m0/s1
  • InChiKey: ZFAHNWWNDFHPOH-YFKPBYRVSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R)-3-allylsulfanyl-2-amino-propanoic acid
  • (2R)-3-(allylthio)-2-aminopropanoic acid
  • (2R)-3-(allylthio)-2-amino-propionic acid
  • (2R)-2-amino-3-prop-2-enylsulfanyl-propanoic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0016 0.0032 0.0147
Onchocerca volvulus 0.0017 0.0047 0.0057
Trichomonas vaginalis glutamate synthase, putative 0.0016 0.0032 0.0066
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0153 0.0774
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.0908 0.2495
Schistosoma mansoni cpg binding protein 0.0061 0.06 0.0593
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.1175 0.3595
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0155 0.0148
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0059 0.0569 0.153
Onchocerca volvulus 0.0029 0.0202 0.0617
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.041 0.4928 0.5121
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0073 0.0093
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0016 0.0032 0.0018
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0155 0.0351
Trypanosoma cruzi DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0073 0.0194
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0032 0.0066
Schistosoma mansoni hypothetical protein 0.0018 0.0063 0.0033
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0103 0.009
Echinococcus multilocularis muscleblind protein 0.0645 0.7855 0.7853
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0103 0.0132
Leishmania major hypothetical protein, conserved 0.0025 0.0153 0.0347
Schistosoma mansoni ap endonuclease 0.0019 0.0073 0.0043
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.055 0.1476
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0202 0.0257
Trypanosoma brucei hypothetical protein, conserved 0.0222 0.2593 0.7294
Echinococcus multilocularis phd:f box containing protein 0.0026 0.0164 0.0151
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0415 0.1249
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.0164 0.0377
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.006
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0016 0.0032 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0086 0.0908 0.2495
Loa Loa (eye worm) DOMON domain-containing protein 0.0017 0.0047 0.006
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0362 0.1723
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0103 0.0094
Leishmania major hypothetical protein, conserved 0.0222 0.2593 0.7294
Echinococcus granulosus JmjC domain containing protein 4 0.0026 0.0164 0.0157
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0387 0.4651 0.8958
Brugia malayi Muscleblind-like protein 0.0645 0.7855 1
Plasmodium vivax ferrodoxin reductase, putative 0.0016 0.0032 0.0147
Brugia malayi jmjC domain containing protein 0.0026 0.0164 0.0209
Brugia malayi hypothetical protein 0.0018 0.0063 0.008
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0103 0.0132
Plasmodium vivax importin-beta 2, putative 0.0057 0.055 0.2812
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0073 0.0118
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0103 0.0075
Loa Loa (eye worm) hypothetical protein 0.0029 0.0202 0.0257
Echinococcus multilocularis MAM 0.0018 0.0063 0.005
Brugia malayi Thioredoxin reductase 0.017 0.1948 0.2479
Leishmania major DNA polymerase eta, putative 0.0298 0.3543 1
Brugia malayi Importin beta-1 subunit 0.0057 0.055 0.07
Echinococcus multilocularis dna polymerase eta 0.0298 0.3543 0.3534
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.1175 0.3595
Echinococcus granulosus phd:f box containing protein 0.0026 0.0164 0.0157
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0103 0.0094
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0103 0.0132
Loa Loa (eye worm) DnaJ domain-containing protein 0.0067 0.0676 0.086
Echinococcus multilocularis lysine specific demethylase 5A 0.0099 0.1062 0.105
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0103 0.009
Schistosoma mansoni jumonji domain containing protein 0.0026 0.0164 0.0138
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.05 0.1511
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.1175 0.3595
Onchocerca volvulus 0.0018 0.0063 0.0114
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0066 0.0664 0.3299
Brugia malayi serine/threonine-protein kinase plk-2 0.0108 0.1175 0.1496
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0052 0.0484 0.2363
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0103 0.0132
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0362 0.1845
Plasmodium falciparum thioredoxin reductase 0.017 0.1948 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0185 0.2138 0.2127
Onchocerca volvulus Alhambra homolog 0.0029 0.0202 0.0617
Trichomonas vaginalis mercuric reductase, putative 0.0059 0.0569 0.1723
Entamoeba histolytica serine/threonine protein kinase, putative 0.0108 0.1175 0.5179
Giardia lamblia DNA damage repair protein 0.006 0.0583 0.241
Echinococcus granulosus lamin dm0 0.0029 0.0202 0.0196
Brugia malayi intermediate filament protein 0.0029 0.0202 0.0257
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0153 0.0347
Schistosoma mansoni DNA polymerase IV / kappa 0.006 0.0583 0.0576
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0387 0.4651 0.8958
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0569 0.153
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0103 0.0132
Brugia malayi hypothetical protein 0.0025 0.0153 0.0195
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Schistosoma mansoni cpg binding protein 0.0065 0.0643 0.0638
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.0155 0.0383
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.1575 0.4395
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0103 0.0132
Brugia malayi polk-prov protein 0.0086 0.0908 0.1155
Echinococcus multilocularis cpg binding protein 0.0065 0.0643 0.0631
Trypanosoma brucei chrX additional, unordered contigs 0.006 0.0583 0.1571
Echinococcus multilocularis musashi 0.0029 0.0202 0.0189
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0387 0.4651 0.8958
Brugia malayi Pre-SET motif family protein 0.0031 0.0224 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.1575 0.4395
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0017
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.1653 0.1642
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0043 0.0375 0.0477
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0203 0.0258
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.02 0.232 0.4439
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0415 0.1249
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0202 0.0257
Trypanosoma cruzi DNA polymerase eta, putative 0.0298 0.3543 1
Schistosoma mansoni DNA polymerase eta 0.0298 0.3543 0.3666
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.1653 0.1709
Trypanosoma brucei trypanothione reductase 0.017 0.1948 0.5457
Plasmodium falciparum glutathione reductase 0.0059 0.0569 0.2909
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0362 0.0363
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.008
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0033 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0103 0.0132
Echinococcus multilocularis dnaJ subfamily C 6 0.0067 0.0676 0.0663
Onchocerca volvulus 0.0017 0.0047 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0224 0.02
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0103 0.0094
Schistosoma mansoni kinase 0.0055 0.0517 0.0507
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0103 0.0094
Brugia malayi CXXC zinc finger family protein 0.0061 0.06 0.0764
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.008
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0207 0.0194
Schistosoma mansoni hypothetical protein 0.0413 0.4964 0.5148
Trichomonas vaginalis glutamate synthase, putative 0.0016 0.0032 0.0066
Echinococcus multilocularis importin subunit beta 1 0.0057 0.055 0.0537
Echinococcus granulosus jumonji domain containing 1A 0.0026 0.0164 0.0157
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0073 0.0774
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0103 0.0132
Loa Loa (eye worm) thioredoxin reductase 0.017 0.1948 0.2479
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0103 0.0094
Trypanosoma brucei unspecified product 0.0133 0.1494 0.4166
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0362 0.094
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0059 0.0569 0.2909
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0103 0.009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0103 0.009
Schistosoma mansoni coup transcription factor 0.0021 0.0103 0.0075
Loa Loa (eye worm) hypothetical protein 0.0025 0.0153 0.0195
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.4964 0.4957
Leishmania major DNA damage repair protein, putative 0.006 0.0583 0.1571
Echinococcus granulosus glutamate synthase 0.0016 0.0032 0.0019
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0073 0.006
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0032 0.0066
Schistosoma mansoni jumonji domain containing protein 0.0139 0.1568 0.1604
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0224 0.1002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0059 0.0569 0.1668
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0103 0.026
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0.0032 0.0066
Mycobacterium ulcerans hypothetical protein 0.006 0.0583 0.1713
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0059 0.0569 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0073 0.0774
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.1175 0.3595
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0059 0.0569 0.0724
Trypanosoma brucei DNA polymerase IV, putative 0.0219 0.2564 0.7213
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0132
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0026 0.0164 0.0138
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0224 0.0211
Loa Loa (eye worm) hypothetical protein 0.0298 0.3543 0.451
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0103 0.009
Brugia malayi Bromodomain containing protein 0.0029 0.0202 0.0257
Echinococcus granulosus snurportin 1 0.0612 0.7442 0.774
Brugia malayi ecdysteroid receptor 0.0021 0.0103 0.0132
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.13 0.1655
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0073 0.0118
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0132
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0041 0.0028
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0362 0.094
Loa Loa (eye worm) glutathione reductase 0.017 0.1948 0.2479
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0569 0.153
Trypanosoma brucei hypothetical protein, conserved 0.0052 0.0484 0.129
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0108 0.1175 0.3257
Entamoeba histolytica hypothetical protein 0.0046 0.0415 0.1737
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0202 0.0257
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0059 0.0569 0.2909
Loa Loa (eye worm) protein-tyrosine phosphatase 0.041 0.4928 0.6274
Toxoplasma gondii exonuclease III APE 0.0019 0.0073 0.0217
Schistosoma mansoni intermediate filament proteins 0.0029 0.0202 0.0177
Brugia malayi jmjC domain containing protein 0.0026 0.0164 0.0209
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0108 0.1175 0.1211
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.06 0.0764
Loa Loa (eye worm) hypothetical protein 0.0031 0.0224 0.0285
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0103 0.0075
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.006
Echinococcus multilocularis lamin 0.0029 0.0202 0.0189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0103 0.0132
Loa Loa (eye worm) hypothetical protein 0.0185 0.2138 0.2721
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0202 0.0887
Plasmodium falciparum ferrodoxin reductase-like protein 0.0016 0.0032 0.0147
Echinococcus granulosus muscleblind protein 0.0645 0.7855 0.8171
Trypanosoma cruzi polo-like protein kinase, putative 0.0108 0.1175 0.3257
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.1175 0.1194
Echinococcus granulosus intermediate filament protein 0.0029 0.0202 0.0196
Loa Loa (eye worm) glutaminase 0.0275 0.3251 0.4139
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0052 0.0484 0.1407
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0415 0.1092
Echinococcus granulosus importin subunit beta 1 0.0057 0.055 0.0559
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0059 0.0569 0.153
Echinococcus multilocularis thioredoxin glutathione reductase 0.0171 0.1968 0.1957
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.243 0.3093
Brugia malayi glutaminase DH11.1 0.0275 0.3251 0.4139
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0059 0.0569 0.2909
Echinococcus multilocularis lysine specific demethylase 6a 0.0026 0.0164 0.0151
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0103 0.0132
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0016 0.0032 0.004
Brugia malayi SEA domain containing protein 0.0017 0.0047 0.006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0087 0.0074
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0103 0.026
Leishmania major hypothetical protein, conserved 0.0026 0.0164 0.0377
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.055 0.2705
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0103 0.0132
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.1295 0.6595
Giardia lamblia PHD finger protein 15 0.0029 0.0202 0.0742
Plasmodium vivax glutathione reductase, putative 0.017 0.1948 1
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0016 0.0032 0.0019
Schistosoma mansoni phd/f-box containing protein 0.0026 0.0164 0.0138
Mycobacterium tuberculosis Probable dehydrogenase 0.0387 0.4651 0.8958
Trypanosoma cruzi DNA damage repair protein, putative 0.006 0.0583 0.1571
Plasmodium vivax DNA repair protein REV1, putative 0.006 0.0583 0.2983
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0103 0.009
Loa Loa (eye worm) hypothetical protein 0.0086 0.0908 0.1155
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0052 0.0484 0.843
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0193 0.0188
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0164 0.0209
Brugia malayi glutamate synthase 0.0016 0.0032 0.004
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0032 0.0066
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0059 0.0569 0.1668
Trichomonas vaginalis DNA polymerase eta, putative 0.0219 0.2564 0.7881
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.1175 0.3595
Leishmania major trypanothione reductase 0.017 0.1948 0.5457
Mycobacterium ulcerans hypothetical protein 0.0026 0.0155 0.0383
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0016 0.0032 0.0018
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.041 0.4928 0.4922
Leishmania major DNA polymerase kappa, putative 0.006 0.0583 0.1571
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0103 0.0132
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0224 0.02
Mycobacterium ulcerans DNA polymerase IV 0.0219 0.2564 0.7867
Mycobacterium tuberculosis Conserved protein 0.0026 0.0155 0.0239
Leishmania major GTP-binding protein, putative 0.0042 0.0362 0.094
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0016 0.0032 0.0147
Trichomonas vaginalis apoptosis inducing factor, putative 0.0016 0.0032 0.0066
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0043 0.0375 0.0477
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0032 0.0066
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0073 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.1575 0.4395
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0052 0.0484 0.843
Trypanosoma cruzi DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Plasmodium vivax SET domain protein, putative 0.0031 0.0224 0.1135
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0.0032 0.0066
Plasmodium falciparum JmjC domain-containing protein, putative 0.0026 0.0164 0.0828
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0059 0.0569 1
Echinococcus multilocularis muscleblind protein 1 0.0645 0.7855 0.7853
Loa Loa (eye worm) glutaminase 2 0.0275 0.3251 0.4139
Trypanosoma brucei hypothetical protein, conserved 0.006 0.0583 0.1571
Schistosoma mansoni jumonji/arid domain-containing protein 0.0102 0.1105 0.1121
Loa Loa (eye worm) TK/ALK protein kinase 0.0018 0.0063 0.008
Brugia malayi MH2 domain containing protein 0.0118 0.13 0.1655
Trypanosoma brucei unspecified product 0.0133 0.1494 0.4166
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0103 0.0132
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0202 0.0189
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0155 0.0446
Schistosoma mansoni phosphatidylserine receptor 0.0026 0.0164 0.0138
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0569 0.153
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0202 0.1021
Plasmodium vivax thioredoxin reductase, putative 0.017 0.1948 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0059 0.0569 0.153
Entamoeba histolytica Ran family GTPase 0.0042 0.0362 0.1495
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0202 0.0196
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0569 0.153
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0146 0.1653 0.2105
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0103 0.0075
Leishmania major DNA polymerase eta, putative 0.0165 0.1886 0.5282
Onchocerca volvulus 0.0237 0.2786 1
Treponema pallidum NADH oxidase 0.0059 0.0569 1
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0016 0.0032 0.0018
Leishmania major phosphopantetheinyl transferase-like protein 0.0052 0.0484 0.129
Schistosoma mansoni hypothetical protein 0.0029 0.0202 0.0177
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0108 0.1175 0.1164
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0103 0.0075
Echinococcus granulosus L aminoadipate semialdehyde 0.0185 0.2138 0.2213
Brugia malayi nuclear receptor NHR-88 0.0021 0.0103 0.0132
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0415 0.1249
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0059 0.0569 0.153
Brugia malayi glutathione reductase 0.017 0.1948 0.2479
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0103 0.009
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0431 0.5188 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.13 0.1655
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0164 0.0209
Schistosoma mansoni ap endonuclease 0.0019 0.0073 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0222 0.2593 0.7294
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.1175 0.3595
Schistosoma mansoni jumonji/arid domain-containing protein 0.0102 0.1105 0.1121
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0362 0.1443
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0569 0.153
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0103 0.0132
Loa Loa (eye worm) hypothetical protein 0.0645 0.7855 1
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0052 0.0484 0.0878
Echinococcus multilocularis glutamate synthase 0.0016 0.0032 0.0018
Onchocerca volvulus 0.0061 0.06 0.2063
Trypanosoma brucei DNA polymerase IV, putative 0.0213 0.2484 0.6984
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0016 0.0032 0.0147
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0159 0.0133
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0059 0.0569 0.0561
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0016 0.0032 0.0018
Trypanosoma brucei polo-like protein kinase 0.0108 0.1175 0.3257
Schistosoma mansoni terminal deoxycytidyl transferase 0.0193 0.224 0.2305
Echinococcus granulosus peregrin 0.0029 0.0202 0.0196
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0052 0.0484 0.1407
Trichomonas vaginalis glutaminase, putative 0.0275 0.3251 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0159 0.1813 0.1876
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0059 0.0569 0.153
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0103 0.0094
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0059 0.0569 0.153
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0387 0.4651 0.8958
Echinococcus multilocularis peregrin 0.0029 0.0202 0.0189
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0103 0.0075
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0052 0.0484 0.843
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0103 0.0132
Schistosoma mansoni lamin 0.0029 0.0202 0.0177
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0026 0.0164 0.0691
Plasmodium falciparum phd finger protein, putative 0.0029 0.0202 0.1021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.1653 0.1642
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0059 0.0569 0.1042
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0059 0.0569 0.2909
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0193 0.224 0.2305
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0207 0.0202
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0103 0.0075
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0103 0.0075
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0185 0.2138 0.2721
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0052 0.0484 0.2476
Mycobacterium ulcerans hypothetical protein 0.0026 0.0155 0.0383
Mycobacterium ulcerans glutaminase 0.0275 0.3251 1
Trypanosoma brucei DNA polymerase IV, putative 0.0219 0.2564 0.7213
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0052 0.0484 0.2476
Brugia malayi ImpB/MucB/SamB family protein 0.0193 0.224 0.2851
Trypanosoma cruzi DNA damage repair protein, putative 0.006 0.0583 0.1571
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.1175 0.3595
Mycobacterium tuberculosis Conserved hypothetical protein 0.0193 0.224 0.4283
Onchocerca volvulus 0.0185 0.2138 0.7646
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0344 0.0331
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0073 0.0081
Schistosoma mansoni hypothetical protein 0.0018 0.0063 0.0033
Plasmodium falciparum thioredoxin reductase 0.0059 0.0569 0.2909
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0103 0.0075
Onchocerca volvulus 0.0029 0.0202 0.0617
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.008
Trichomonas vaginalis ran, putative 0.0042 0.0362 0.1085
Echinococcus multilocularis jumonji domain containing 1A 0.0026 0.0164 0.0151
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0016 0.0032 0.0019
Brugia malayi Pre-SET motif family protein 0.0209 0.243 0.3093
Loa Loa (eye worm) jmjC domain-containing protein 0.0102 0.1105 0.1407
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0103 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0103 0.0132
Echinococcus granulosus thioredoxin glutathione reductase 0.0171 0.1968 0.2037
Trypanosoma cruzi DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Loa Loa (eye worm) hypothetical protein 0.0645 0.7855 1
Trypanosoma brucei hypothetical protein, conserved 0.006 0.0583 0.1571
Trypanosoma cruzi hypothetical protein, conserved 0.0222 0.2593 0.7294
Mycobacterium tuberculosis Probable oxidoreductase 0.0431 0.5188 1
Trypanosoma brucei DNA damage repair protein, putative 0.006 0.0583 0.1571
Brugia malayi jmjC domain containing protein 0.0102 0.1105 0.1407
Trypanosoma brucei unspecified product 0.0213 0.2484 0.6984
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0612 0.7442 0.9474
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0103 0.0132
Echinococcus granulosus lysine specific demethylase 5A 0.0102 0.1105 0.1138
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0073 0.0361
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.041 0.4928 0.5112
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0073 0.0182
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0073 0.0194
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0073 0.0361
Loa Loa (eye worm) hypothetical protein 0.0067 0.0671 0.0854
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0073 0.0118
Brugia malayi PHD-finger family protein 0.0029 0.0202 0.0257
Trichomonas vaginalis protein kinase inhibitor, putative 0.0067 0.0676 0.2054
Schistosoma mansoni microtubule-associated protein tau 0.0787 0.9611 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0153 0.0774
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0185 0.2138 0.2198
Schistosoma mansoni cpg binding protein 0.0065 0.0643 0.0638
Schistosoma mansoni ran 0.0042 0.0362 0.0345
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0033 0.0042
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0153 0.0347
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.1653 0.1693
Leishmania major importin beta-1 subunit, putative 0.0046 0.0415 0.1092
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.02 0.232 0.6518
Leishmania major DNA polymerase kappa, putative 0.02 0.232 0.6518
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0032 0.0066
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0059 0.0569 0.153
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0132
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0155 0.0383
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0026 0.0164 0.0691
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.1468 0.1499
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0103 0.0132
Plasmodium falciparum glutathione reductase 0.017 0.1948 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0103 0.0094
Trypanosoma brucei DNA polymerase eta, putative 0.0298 0.3543 1
Echinococcus granulosus dnaJ subfamily C 6 0.0067 0.0676 0.069
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0165 0.1886 0.9679
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0016 0.0032 0.004
Echinococcus granulosus cpg binding protein 0.0065 0.0643 0.0656
Loa Loa (eye worm) histone methyltransferase 0.002 0.0087 0.0111
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0073 0.0118
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0026 0.0164 0.0377
Mycobacterium leprae conserved hypothetical protein 0.0052 0.0484 0.0878
Mycobacterium tuberculosis Probable reductase 0.0387 0.4651 0.8958
Trichomonas vaginalis glutathione reductase, putative 0.0059 0.0569 0.1723
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0052 0.0484 0.2363
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.055 0.1476
Loa Loa (eye worm) hypothetical protein 0.0029 0.0202 0.0257
Schistosoma mansoni lamin 0.0029 0.0202 0.0177
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0016 0.0032 0.0066
Toxoplasma gondii NADPH-glutathione reductase 0.0059 0.0569 0.2803
Plasmodium falciparum DNA repair protein REV1, putative 0.006 0.0583 0.2983
Echinococcus granulosus microtubule associated protein 2 0.0787 0.9611 1
Brugia malayi jmjC domain containing protein 0.0159 0.1813 0.2309
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0103 0.0132
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0108 0.1175 0.1496
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0362 0.0461
Loa Loa (eye worm) hypothetical protein 0.0057 0.055 0.07
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0202 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0583 0.1571
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0362 0.1845
Echinococcus multilocularis lamin dm0 0.0029 0.0202 0.0189
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0059 0.0569 0.153
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0344 0.0345
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0146 0.1653 0.2105
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.017 0.1948 0.3716
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0387 0.4651 0.8958
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0103 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0103 0.0132
Echinococcus multilocularis JmjC domain containing protein 4 0.0026 0.0164 0.0151
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.232 0.6518
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0155 0.0351
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0431 0.5188 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0008
Trichomonas vaginalis set domain proteins, putative 0.0237 0.2786 0.8565
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Echinococcus granulosus lysine specific demethylase 6a 0.0026 0.0164 0.0157
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0193 0.224 0.232
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0059 0.0569 0.1668
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0073 0.0188
Echinococcus multilocularis microtubule associated protein 2 0.0787 0.9611 0.9611
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0103 0.026
Brugia malayi steroid hormone receptor 0.0021 0.0103 0.0132
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0155 0.0383
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0132
Loa Loa (eye worm) programmed cell death 8 0.0016 0.0032 0.004
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0041 0.0027
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0153 0.0636
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0103 0.0132
Onchocerca volvulus 0.0031 0.0224 0.0697
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0219 0.2564 0.7881
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0583 0.1571
Brugia malayi Protein-tyrosine phosphatase containing protein 0.041 0.4928 0.6274
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.1653 0.1693
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0041 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0224 0.02
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0103 0.0132
Giardia lamblia NADH oxidase lateral transfer candidate 0.0059 0.0569 0.2347
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0016 0.0032 0.0147
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0103 0.0075
Brugia malayi jmjC domain containing protein 0.0026 0.0164 0.0209
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0153 0.0774
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0016 0.0032 0.004
Onchocerca volvulus 0.0017 0.0047 0.0057
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.0032 0.0066
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0362 0.0461
Toxoplasma gondii ImpB/MucB/SamB family protein 0.006 0.0583 0.2878
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0132
Schistosoma mansoni ran 0.0042 0.0362 0.0345
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0059 0.0569 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0103 0.009
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0016 0.0032 0.0019
Echinococcus multilocularis snurportin 1 0.0612 0.7442 0.7439
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0103 0.0075
Brugia malayi jmjC domain containing protein 0.0026 0.0164 0.0209
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0041 0.0028
Echinococcus multilocularis dna polymerase kappa 0.0219 0.2564 0.2554
Loa Loa (eye worm) hypothetical protein 0.0026 0.0164 0.0209
Mycobacterium ulcerans DNA polymerase IV 0.0219 0.2564 0.7867
Schistosoma mansoni hypothetical protein 0.0067 0.0676 0.0672
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.1653 0.1709
Onchocerca volvulus 0.0017 0.0047 0.0057
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0362 0.094
Brugia malayi Protein kinase domain containing protein 0.0018 0.0063 0.008
Giardia lamblia DINP protein human, muc B family 0.02 0.232 1
Brugia malayi nuclear hormone receptor 0.0021 0.0103 0.0132
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0362 0.0349
Onchocerca volvulus 0.0021 0.0103 0.026
Entamoeba histolytica deoxycytidyl transferase, putative 0.0193 0.224 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0165 0.1886 0.5282
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0059 0.0569 0.2803
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.1653 0.1693
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0059 0.0569 0.153
Toxoplasma gondii thioredoxin reductase 0.017 0.1948 1
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0016 0.0032 0.0019
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0016 0.0032 0.0019
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.0164 0.0377
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.004
Entamoeba histolytica hypothetical protein 0.0052 0.0484 0.2051
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0016 0.0032 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.05 0.1511
Plasmodium falciparum importin beta, putative 0.0057 0.055 0.2812
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0103 0.0075
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0193 0.224 0.223
Schistosoma mansoni protein phosphatase 2C 0.0026 0.0164 0.0138
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0224 0.0219
Trypanosoma cruzi trypanothione reductase, putative 0.0059 0.0569 0.153
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0202 0.0257
Onchocerca volvulus Serine\/threonine kinase homolog 0.0108 0.1175 0.4153
Schistosoma mansoni importin beta-1 0.0057 0.055 0.0541
Trypanosoma cruzi DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Echinococcus granulosus MAM 0.0018 0.0063 0.0052
Trypanosoma cruzi trypanothione reductase, putative 0.017 0.1948 0.5457
Loa Loa (eye worm) hypothetical protein 0.0021 0.0103 0.0132
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0431 0.5188 1
Brugia malayi DnaJ domain containing protein 0.0067 0.0676 0.086
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0016 0.0032 0.0019
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0153 0.0347
Schistosoma mansoni glutaminase 0.0275 0.3251 0.3361
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0103 0.0094
Giardia lamblia Kinase, PLK 0.0108 0.1175 0.4997
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0155 0.0351
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0103 0.0075
Echinococcus granulosus dnaJ subfamily B 0.0413 0.4964 0.5158
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0016 0.0032 0.004
Schistosoma mansoni hypothetical protein 0.0612 0.7442 0.7736
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0059 0.0569 0.0579
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0008
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0059 0.0569 0.153
Echinococcus granulosus dna polymerase kappa 0.0219 0.2564 0.2658
Brugia malayi hypothetical protein 0.0016 0.0041 0.0053
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0059 0.0569 0.0556
Loa Loa (eye worm) hypothetical protein 0.0026 0.0164 0.0209
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0103 0.0132
Trypanosoma brucei DNA damage repair protein, putative 0.006 0.0583 0.1571
Brugia malayi RNA, U transporter 1 0.0163 0.1863 0.2372
Trypanosoma cruzi polo-like protein kinase, putative 0.0108 0.1175 0.3257
Brugia malayi Muscle positioning protein 4 0.0017 0.0047 0.006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0224 0.02
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0164 0.0209
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0103 0.009
Onchocerca volvulus 0.0018 0.0063 0.0114
Loa Loa (eye worm) hypothetical protein 0.0029 0.0195 0.0248
Trypanosoma brucei DNA polymerase kappa, putative 0.0219 0.2564 0.7213
Onchocerca volvulus 0.0017 0.0047 0.0057
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0193 0.224 0.2851
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.0155 0.0239
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0073 0.0062
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0155 0.0142
Echinococcus granulosus dna polymerase eta 0.0298 0.3543 0.3678
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0224 0.0211
Echinococcus granulosus lamin 0.0029 0.0202 0.0196
Plasmodium vivax JmjC domain containing protein 0.0026 0.0164 0.0828
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0016 0.0032 0.0066
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0159 0.1813 0.1803
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0087 0.0077
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0073 0.0093
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0202 0.0887
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0569 0.153
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0589 0.075
Brugia malayi ImpB/MucB/SamB family protein 0.0298 0.3543 0.451

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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