Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Cathepsin F homolog | 0.0755 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0755 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0714 | 0.8838 | 0.8838 |
Echinococcus granulosus | cathepsin l1 | 0.0511 | 0.3182 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0755 | 1 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0755 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0755 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0755 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0511 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0755 | 1 | 1 |
Onchocerca volvulus | 0.0755 | 1 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0755 | 1 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0755 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0755 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0755 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0755 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0755 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Onchocerca volvulus | 0.0755 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0755 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0511 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0755 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0755 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0755 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0755 | 1 | 1 |
Onchocerca volvulus | 0.0755 | 1 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0714 | 0.8838 | 0.8838 |
Loa Loa (eye worm) | hypothetical protein | 0.0755 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0511 | 0.3182 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0755 | 1 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0755 | 1 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0714 | 0.8838 | 0.8838 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0755 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0755 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0755 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0755 | 1 | 0.5 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0755 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0755 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0755 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.3182 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0755 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0755 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0755 | 1 | 1 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0714 | 0.8838 | 0.8838 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0755 | 1 | 1 |
Onchocerca volvulus | 0.0755 | 1 | 1 | |
Leishmania major | cysteine peptidase A (CPA) | 0.0755 | 1 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0755 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0511 | 0.3182 | 0.3182 |
Echinococcus multilocularis | cysteine protease | 0.0755 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0714 | 0.8838 | 0.8838 |
Brugia malayi | Cathepsin L-like precursor | 0.0511 | 0.3182 | 0.3182 |
Onchocerca volvulus | 0.0755 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.3182 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0755 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0755 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0511 | 0.3182 | 0.3182 |
Onchocerca volvulus | 0.0755 | 1 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.0755 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0714 | 0.8838 | 0.8838 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0714 | 0.8838 | 0.8296 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0755 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0755 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0714 | 0.8838 | 0.8838 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0511 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Onchocerca volvulus | 0.0755 | 1 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0755 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0755 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0755 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0755 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0714 | 0.8838 | 0.8838 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0755 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0755 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0755 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0755 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0714 | 0.8838 | 0.8838 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0714 | 0.8838 | 0.8838 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0755 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0755 | 1 | 1 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 22818039 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.