Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | DNA repair protein REV1, putative | 0.002 | 0.0319 | 0.1672 |
Leishmania major | DNA damage repair protein, putative | 0.002 | 0.0319 | 0.0261 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0163 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.5904 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.1173 | 0.1987 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0028 | 0.056 | 0.0948 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0605 | 0.1803 |
Brugia malayi | jmjC domain containing protein | 0.0093 | 0.2526 | 0.4278 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.002 | 0.0319 | 0.0189 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0262 | 0.5 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.009 | 0.2459 | 0.725 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0058 | 0.1475 | 0.4003 |
Echinococcus granulosus | jumonji domain containing protein | 0.0039 | 0.0898 | 0.1522 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0745 | 0.1262 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0262 | 0.0443 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 0.2526 | 0.4278 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0066 | 0.1704 | 0.2887 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.002 | 0.0292 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.5904 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0203 | 0.5904 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0066 | 0.1704 | 0.2887 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0745 | 0.1262 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0118 | 0.3293 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0262 | 0.0443 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0762 | 0.1291 |
Brugia malayi | Carboxylesterase family protein | 0.0203 | 0.5904 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0762 | 0.1291 |
Echinococcus granulosus | acetylcholinesterase | 0.0203 | 0.5904 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0079 | 0.2099 | 0.1886 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0745 | 0.1262 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 0.2526 | 0.4278 |
Echinococcus granulosus | acetylcholinesterase | 0.0203 | 0.5904 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0292 | 0.0495 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0118 | 0.3293 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0028 | 0.056 | 0.0948 |
Schistosoma mansoni | acetylcholinesterase | 0.0034 | 0.0745 | 0.1262 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.002 | 0.0292 | 0.0495 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0066 | 0.1704 | 0.2887 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0163 | 0.0277 |
Echinococcus multilocularis | neuroligin | 0.0034 | 0.0745 | 0.1262 |
Leishmania major | small ubiquitin protein, putative | 0.003 | 0.0605 | 0.1562 |
Trypanosoma brucei | hypothetical protein, conserved | 0.002 | 0.0319 | 0.0189 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0045 | 0.1074 | 0.268 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0262 | 0.0248 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0096 | 0.2628 | 0.2617 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0163 | 0.0277 |
Trypanosoma brucei | unspecified product | 0.0045 | 0.1081 | 0.2703 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0163 | 0.0277 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0762 | 0.0749 |
Brugia malayi | Carboxylesterase family protein | 0.0203 | 0.5904 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0014 | 0.0024 |
Plasmodium vivax | small ubiquitin-related modifier, putative | 0.003 | 0.0605 | 1 |
Echinococcus granulosus | flap endonuclease 1 | 0.0025 | 0.0468 | 0.0792 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0034 | 0.0745 | 0.2229 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.1173 | 0.1987 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0163 | 0.0277 |
Echinococcus multilocularis | dna polymerase kappa | 0.0118 | 0.3293 | 0.5577 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0025 | 0.0468 | 0.0679 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0745 | 0.1262 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0262 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.1173 | 0.1987 |
Onchocerca volvulus | 0.0034 | 0.0745 | 1 | |
Brugia malayi | Bloom's syndrome protein homolog | 0.002 | 0.0292 | 0.0495 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.002 | 0.0319 | 0.0189 |
Loa Loa (eye worm) | carboxylesterase | 0.0203 | 0.5904 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0163 | 0.0277 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0203 | 0.5904 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0706 | 0.1196 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0118 | 0.3293 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0292 | 0.0495 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0034 | 0.0745 | 0.1262 |
Echinococcus multilocularis | peregrin | 0.0028 | 0.056 | 0.0948 |
Schistosoma mansoni | gliotactin | 0.0034 | 0.0745 | 0.1262 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Trypanosoma cruzi | small ubiquitin protein, putative | 0.003 | 0.0605 | 0.1133 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0745 | 0.1262 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0163 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1173 | 0.1987 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.056 | 0.3669 |
Trypanosoma brucei | unspecified product | 0.0045 | 0.1081 | 0.2703 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2459 | 0.4165 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.0742 | 0.1256 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0034 | 0.0742 | 0.1256 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0066 | 0.1704 | 0.2887 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0039 | 0.0898 | 0.1522 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0203 | 0.5904 | 1 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0025 | 0.0468 | 0.2534 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0745 | 0.1262 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.002 | 0.0319 | 0.0189 |
Leishmania major | DNA polymerase eta, putative | 0.009 | 0.2459 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.056 | 0.0948 |
Entamoeba histolytica | Flap nuclease, putative | 0.0025 | 0.0468 | 0.0454 |
Schistosoma mansoni | ubiquitin-like protein sumo/smt3-related | 0.003 | 0.0605 | 0.1025 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0034 | 0.0745 | 0.3261 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0762 | 0.0749 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0762 | 0.1291 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0034 | 0.0745 | 0.1262 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0034 | 0.0745 | 0.3261 |
Giardia lamblia | PHD finger protein 15 | 0.0028 | 0.056 | 0.0306 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0118 | 0.3293 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0163 | 0.0277 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0118 | 0.3293 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0045 | 0.1074 | 0.3697 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0163 | 0.0277 |
Brugia malayi | Bromodomain containing protein | 0.0028 | 0.056 | 0.0948 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0034 | 0.0745 | 0.1262 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0034 | 0.0745 | 0.1262 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.0742 | 0.1256 |
Echinococcus granulosus | bloom syndrome protein | 0.002 | 0.0292 | 0.0495 |
Echinococcus multilocularis | dna polymerase eta | 0.009 | 0.2459 | 0.4165 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0033 | 0.0713 | 0.5557 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0163 | 0.0277 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0762 | 0.1291 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0105 | 0.2899 | 0.87 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0292 | 0.0375 |
Plasmodium falciparum | small ubiquitin-related modifier | 0.003 | 0.0605 | 1 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.0292 | 0.0139 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.056 | 0.8684 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.1944 | 0.3293 |
Echinococcus multilocularis | acetylcholinesterase | 0.0203 | 0.5904 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0745 | 0.1262 |
Echinococcus granulosus | Small ubiquitin modifier 2 | 0.003 | 0.0605 | 0.1025 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0292 | 0.0375 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.0742 | 0.1256 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0762 | 0.0749 |
Trypanosoma brucei | small ubiquitin-related modifier | 0.003 | 0.0605 | 0.1133 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0292 | 0.0495 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0028 | 0.056 | 0.0948 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.009 | 0.2459 | 0.725 |
Echinococcus multilocularis | ubiquitin | 0.001 | 0.0014 | 0.0024 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.0292 | 0.0849 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0058 | 0.1475 | 0.4003 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0025 | 0.0468 | 0.0679 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0045 | 0.1074 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.1908 | 0.3231 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0025 | 0.0468 | 0.0937 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Brugia malayi | Ubiquitin-like protein SMT3 | 0.003 | 0.0605 | 0.1025 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0262 | 0.0756 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0.056 | 0.7517 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0034 | 0.0745 | 0.2229 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0745 | 0.1262 |
Schistosoma mansoni | DNA helicase recq1 | 0.002 | 0.0292 | 0.0495 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0262 | 0.0856 |
Loa Loa (eye worm) | SMO-1 protein | 0.003 | 0.0605 | 0.1025 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0072 | 0.1908 | 0.543 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Trypanosoma cruzi | small ubiquitin protein, putative | 0.003 | 0.0605 | 0.1133 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0079 | 0.2099 | 0.8358 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.056 | 0.0948 |
Entamoeba histolytica | Rad52/22 family double-strand break repair protein, putative | 0.0096 | 0.2628 | 0.2617 |
Brugia malayi | hypothetical protein | 0.001 | 0.0014 | 0.0024 |
Leishmania major | DNA polymerase kappa, putative | 0.0079 | 0.2099 | 0.8358 |
Schistosoma mansoni | DNA helicase recq5 | 0.002 | 0.0292 | 0.0495 |
Trypanosoma brucei | hypothetical protein, conserved | 0.002 | 0.0319 | 0.0189 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0028 | 0.056 | 0.0948 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.002 | 0.0292 | 0.0887 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0319 | 0.0261 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0025 | 0.0468 | 0.5997 |
Echinococcus multilocularis | Small ubiquitin modifier 2 | 0.003 | 0.0605 | 0.1025 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0706 | 0.1196 |
Onchocerca volvulus | 0.001 | 0.0014 | 0.0187 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0034 | 0.0745 | 0.1262 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0066 | 0.1704 | 0.1693 |
Echinococcus granulosus | dna polymerase kappa | 0.0118 | 0.3293 | 0.5577 |
Brugia malayi | Carboxylesterase family protein | 0.0034 | 0.0745 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0745 | 0.1262 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.002 | 0.0319 | 0.1672 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0163 | 0.0277 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0025 | 0.0468 | 0.0792 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0.056 | 0.8684 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0163 | 0.0277 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.002 | 0.0292 | 0.0495 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0066 | 0.1704 | 0.8038 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0262 | 0.0756 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.148 | 0.2507 |
Loa Loa (eye worm) | carboxylesterase | 0.0034 | 0.0745 | 0.1262 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0034 | 0.0745 | 0.1262 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.002 | 0.0319 | 0.0707 |
Onchocerca volvulus | 0.0034 | 0.0745 | 1 | |
Loa Loa (eye worm) | RecQ helicase | 0.002 | 0.0292 | 0.0495 |
Echinococcus multilocularis | acetylcholinesterase | 0.0203 | 0.5904 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0203 | 0.5904 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.002 | 0.0292 | 0.0495 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0262 | 0.0443 |
Giardia lamblia | Sentrin | 0.003 | 0.0605 | 0.0353 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0118 | 0.3293 | 1 |
Echinococcus granulosus | peregrin | 0.0028 | 0.056 | 0.0948 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.009 | 0.2459 | 0.4165 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0163 | 0.0277 |
Entamoeba histolytica | ubiquitin like protein | 0.003 | 0.0605 | 0.0592 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.002 | 0.0319 | 0.0189 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.002 | 0.0319 | 0.0541 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.0292 | 0.0101 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0034 | 0.0745 | 0.3261 |
Brugia malayi | polk-prov protein | 0.0072 | 0.1908 | 0.3231 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0079 | 0.2099 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0762 | 0.1291 |
Mycobacterium ulcerans | hypothetical protein | 0.002 | 0.0319 | 0.0189 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0034 | 0.0745 | 0.1594 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0034 | 0.0745 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0745 | 0.1262 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0072 | 0.1908 | 0.543 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Echinococcus multilocularis | bloom syndrome protein | 0.002 | 0.0292 | 0.0495 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.002 | 0.0319 | 0.0189 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0262 | 0.0443 |
Echinococcus granulosus | ubiquitin | 0.001 | 0.0014 | 0.0024 |
Loa Loa (eye worm) | carboxylesterase | 0.0034 | 0.0745 | 0.1262 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Giardia lamblia | DNA damage repair protein | 0.002 | 0.0319 | 0.0059 |
Schistosoma mansoni | DNA polymerase eta | 0.009 | 0.2459 | 0.4165 |
Onchocerca volvulus | 0.0034 | 0.0745 | 1 | |
Trypanosoma brucei | DNA damage repair protein, putative | 0.002 | 0.0319 | 0.0189 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0025 | 0.0468 | 0.1384 |
Onchocerca volvulus | 0.0034 | 0.0745 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0745 | 0.1262 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0066 | 0.1704 | 0.2887 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.0292 | 0.0849 |
Brugia malayi | Flap endonuclease-1 | 0.0025 | 0.0468 | 0.0792 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0706 | 0.1196 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.002 | 0.0292 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0745 | 0.1262 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0034 | 0.0745 | 0.1262 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0262 | 0.0443 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.002 | 0.0292 | 0.0849 |
Onchocerca volvulus | 0.0034 | 0.0745 | 1 | |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0025 | 0.0468 | 0.0792 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0058 | 0.1475 | 0.4003 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0025 | 0.0468 | 0.0211 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0066 | 0.1704 | 0.2887 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0262 | 0.0443 |
Echinococcus granulosus | dna polymerase eta | 0.009 | 0.2459 | 0.4165 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.0742 | 0.1256 |
Toxoplasma gondii | small ubiquitin family modifier, putative | 0.003 | 0.0605 | 0.4225 |
Trypanosoma brucei | unspecified product | 0.0105 | 0.2899 | 0.87 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1177 | 0.1994 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0745 | 0.1262 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.002 | 0.0292 | 0.0887 |
Giardia lamblia | DNA repair protein RAD52 | 0.0337 | 1 | 1 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.002 | 0.0292 | 0.0495 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0762 | 0.0749 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0034 | 0.0742 | 0.1256 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0118 | 0.3293 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0079 | 0.2099 | 0.606 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.002 | 0.0319 | 0.0189 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0163 | 0.0277 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0034 | 0.0745 | 0.1262 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.0292 | 0.0101 |
Plasmodium falciparum | flap endonuclease 1 | 0.0025 | 0.0468 | 0.5997 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.056 | 0.3669 |
Schistosoma mansoni | flap endonuclease-1 | 0.0023 | 0.0394 | 0.0667 |
Echinococcus granulosus | neuroligin | 0.0034 | 0.0745 | 0.1262 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.056 | 0.0948 |
Entamoeba histolytica | recQ family helicase, putative | 0.002 | 0.0292 | 0.0279 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | > 44 uM | Cytotoxicity against human HuH7 cells after 3 days by measuring conversion of nonfluorescent calcein-AM into fluorescent calcein | ChEMBL. | 22664130 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.