Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | HMG-CoA reductase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.1037 | 0.1416 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.1282 | 0.122 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.1186 | 0.2552 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0018 | 0.0026 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.1186 | 1 |
Schistosoma mansoni | single-minded | 0.0049 | 0.1115 | 0.1052 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.0706 | 0.1503 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.0092 | 0.0133 |
Onchocerca volvulus | 0.0055 | 0.1282 | 0.183 | |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0015 | 0.0071 | 0.0053 |
Leishmania major | basic transcription factor 3a, putative | 0.0036 | 0.0706 | 0.1503 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0165 | 0.4595 | 0.4556 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0015 | 0.0092 | 0.0074 |
Echinococcus granulosus | Ankyrin | 0.0015 | 0.0074 | 0.0057 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0165 | 0.4595 | 0.4585 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0514 | 0.0447 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.174 | 0.1681 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0018 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0722 | 0.1043 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0019 | 0.0201 | 0.0243 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.1282 | 0.1267 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.0092 | 0.0162 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0651 | 0.0941 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.1113 | 0.105 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0018 | 0.0026 |
Echinococcus granulosus | single minded 2 | 0.0037 | 0.073 | 0.0713 |
Brugia malayi | bHLH-PAS transcription factor | 0.0037 | 0.073 | 0.0966 |
Schistosoma mansoni | rotamase | 0.0034 | 0.0651 | 0.0584 |
Echinococcus multilocularis | protein dispatched 1 | 0.0068 | 0.1675 | 0.1661 |
Mycobacterium leprae | Possible regulatory protein | 0.0013 | 0.0018 | 0.5 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0242 | 0.6893 | 0.6887 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0046 | 0.1002 | 0.1447 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.2716 | 0.3924 |
Echinococcus granulosus | transcription factor btf3 | 0.0036 | 0.0706 | 0.0689 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0608 | 0.0591 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0565 | 0.0548 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0018 | 0.0026 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0013 | 0.0018 | 0.0026 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0046 | 0.1002 | 0.2151 |
Echinococcus multilocularis | transcription factor btf3 | 0.0036 | 0.0706 | 0.0689 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.2954 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0722 | 0.1043 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0608 | 0.0591 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0036 | 0.0723 | 0.1402 |
Onchocerca volvulus | 0.0037 | 0.073 | 0.103 | |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0015 | 0.0071 | 0.000000064252 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0046 | 0.1002 | 0.0986 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.2797 | 0.2746 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0078 | 0.196 | 0.2831 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0015 | 0.0092 | 0.0108 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.1186 | 0.675 |
Echinococcus granulosus | lamin | 0.0055 | 0.1282 | 0.1267 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0651 | 0.0941 |
Echinococcus multilocularis | lamin | 0.0055 | 0.1282 | 0.1267 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0033 | 0.0627 | 0.1188 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 1 | 1 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0046 | 0.1002 | 0.2022 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0075 | 0.1877 | 0.1863 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0568 | 0.0551 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.0651 | 0.092 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0033 | 0.0627 | 0.0637 |
Brugia malayi | PAS domain containing protein | 0.0049 | 0.1115 | 0.1531 |
Onchocerca volvulus | 0.0055 | 0.1282 | 0.183 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.1483 | 0.1423 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0018 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0071 | 0.0077 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1037 | 0.1021 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0036 | 0.0706 | 0.2229 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0568 | 0.0729 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.1282 | 0.1776 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0111 | 0.2954 | 0.2904 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0037 | 0.073 | 0.0713 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0036 | 0.0723 | 0.1541 |
Brugia malayi | hypoxia-induced factor 1 | 0.0153 | 0.4222 | 0.6085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0443 | 0.064 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.1483 | 0.1468 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.4595 | 0.6657 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.2716 | 0.3877 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.0092 | 0.0133 |
Echinococcus multilocularis | Ankyrin | 0.0015 | 0.0074 | 0.0057 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0372 | 0.0537 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0213 | 0.6042 | 0.8762 |
Brugia malayi | Protein kinase domain containing protein | 0.0015 | 0.0071 | 0.000000093516 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0722 | 0.1043 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0627 | 0.133 |
Onchocerca volvulus | 0.0049 | 0.1113 | 0.1585 | |
Schistosoma mansoni | lamin | 0.0055 | 0.1282 | 0.122 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.0092 | 0.0133 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.1282 | 0.1776 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0015 | 0.0071 | 0.0053 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.1186 | 0.2552 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0608 | 0.0591 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0608 | 0.0541 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0242 | 0.6893 | 0.6887 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0015 | 0.0074 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.6893 | 1 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0165 | 0.4595 | 0.6631 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0046 | 0.1002 | 0.1447 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0033 | 0.0627 | 0.133 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0372 | 0.0537 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.1337 | 0.8399 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1037 | 0.1021 |
Onchocerca volvulus | 0.0031 | 0.0568 | 0.0797 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0522 | 0.0753 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0568 | 0.0551 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0015 | 0.0092 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4607 | 0.6675 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.1282 | 0.1839 |
Echinococcus multilocularis | expressed protein | 0.0034 | 0.0651 | 0.0634 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0078 | 0.196 | 1 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0036 | 0.0723 | 0.1541 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0371 | 0.0536 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0078 | 0.196 | 0.2831 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0018 | 0.0026 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.1483 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0608 | 0.0541 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0372 | 0.0537 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.174 | 0.2505 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.1483 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.1282 | 0.1839 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.2954 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1037 | 0.0973 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0371 | 0.0536 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.1282 | 0.1267 |
Brugia malayi | Pre-SET motif family protein | 0.0213 | 0.6042 | 0.8752 |
Schistosoma mansoni | lamin | 0.0055 | 0.1282 | 0.122 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0111 | 0.2954 | 0.2942 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0166 | 0.4607 | 0.6649 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0018 | 0.0026 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0165 | 0.4595 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.1483 | 0.1468 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0046 | 0.1011 | 0.1445 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0165 | 0.4595 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0027 | 0.0429 | 0.0412 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0068 | 0.1675 | 0.1661 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0046 | 0.1002 | 0.1614 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0078 | 0.196 | 0.2831 |
Onchocerca volvulus | 0.0243 | 0.6928 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0329 | 0.026 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1037 | 0.0973 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.0516 | 0.0653 |
Brugia malayi | hypothetical protein | 0.0052 | 0.1186 | 0.1635 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0034 | 0.0651 | 0.0907 |
Brugia malayi | beta-NAC-like protein | 0.0036 | 0.0706 | 0.0931 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0514 | 0.0722 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.1113 | 0.105 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0329 | 0.0312 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.174 | 0.2447 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0046 | 0.1002 | 0.2022 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0706 | 0.1019 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.2716 | 0.3877 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0046 | 0.1002 | 0.1432 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.1282 | 0.1267 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0608 | 0.0591 |
Echinococcus multilocularis | geminin | 0.0345 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1483 | 0.1949 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0034 | 0.0651 | 0.085 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.1483 | 0.1423 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1675 | 0.2411 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0565 | 0.0497 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0015 | 0.0071 | 0.0053 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.1186 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0565 | 0.0497 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.1037 | 0.0973 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1252 | 0.1796 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0111 | 0.2954 | 0.2942 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.1037 | 0.1482 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0651 | 0.0941 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0514 | 0.065 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0568 | 0.0551 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0608 | 0.0591 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0651 | 0.0939 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0608 | 0.0859 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0722 | 0.1043 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0165 | 0.4595 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0515 | 0.0498 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0451 | 0.0651 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0372 | 0.0537 |
Toxoplasma gondii | NAC domain-containing protein | 0.0036 | 0.0706 | 0.1505 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.2954 | 1 |
Echinococcus granulosus | expressed protein | 0.0034 | 0.0651 | 0.0634 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0015 | 0.0071 | 0.0053 |
Brugia malayi | CHE-14 protein | 0.0068 | 0.1675 | 0.2352 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0046 | 0.1002 | 0.2151 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1282 | 0.1839 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0608 | 0.0541 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0039 | 0.0802 | 0.1158 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0046 | 0.1002 | 0.0938 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0068 | 0.1675 | 0.1661 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0165 | 0.4595 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0608 | 0.0859 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0329 | 0.0312 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0568 | 0.0501 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0013 | 0.0018 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0399 | 0.0554 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0153 | 0.4222 | 0.6115 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0608 | 0.0591 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.1186 | 0.2552 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0068 | 0.1675 | 0.1661 |
Echinococcus multilocularis | protein patched | 0.0068 | 0.1675 | 0.1661 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0075 | 0.1877 | 0.1863 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0049 | 0.1115 | 0.1052 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0015 | 0.0092 | 0.0031 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0018 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0046 | 0.1002 | 0.1447 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.2954 | 0.2904 |
Onchocerca volvulus | 0.0029 | 0.0514 | 0.0718 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1186 | 0.1699 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.1113 | 0.1528 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0068 | 0.1675 | 0.1616 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.0651 | 0.0939 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0443 | 0.064 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.0092 | 0.0162 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0568 | 0.0501 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0627 | 0.133 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0568 | 0.0801 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0608 | 0.0788 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.0516 | 0.0725 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0568 | 0.0501 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0651 | 0.0941 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0568 | 0.0501 |
Echinococcus granulosus | death domain containing protein | 0.0015 | 0.0071 | 0.0053 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0046 | 0.1002 | 0.2151 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0046 | 0.1002 | 0.1614 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0565 | 0.0548 |
Onchocerca volvulus | Netrin receptor homolog | 0.0015 | 0.0071 | 0.0076 |
Schistosoma mansoni | transcription factor btf3 | 0.0036 | 0.0706 | 0.064 |
Loa Loa (eye worm) | ICD-1 protein | 0.0036 | 0.0706 | 0.1001 |
Brugia malayi | Uncoordinated protein 44 | 0.0015 | 0.0071 | 0.000000093516 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.1037 | 0.1021 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1483 | 0.1949 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0015 | 0.0092 | 0.0162 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0165 | 0.4595 | 0.4585 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0551 | 0.0796 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0015 | 0.0092 | 0.0021 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.1537 | 0.1476 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0371 | 0.0536 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1483 | 0.1949 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0074 | 0.0082 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0651 | 0.0941 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0036 | 0.0706 | 0.1364 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0027 | 0.0429 | 0.0412 |
Brugia malayi | hypothetical protein | 0.0242 | 0.6893 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0243 | 0.6925 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.1037 | 0.1021 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0046 | 0.1002 | 0.1366 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0608 | 0.0541 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.0092 | 0.0133 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.1186 | 1 |
Brugia malayi | Death domain containing protein | 0.0015 | 0.0071 | 0.000000093516 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0651 | 0.0941 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0608 | 0.0788 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.1675 | 0.242 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0015 | 0.0071 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0429 | 0.0598 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0036 | 0.0706 | 0.0341 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0451 | 0.0651 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0046 | 0.1002 | 0.2151 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.1186 | 0.243 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0722 | 0.1043 |
Brugia malayi | hypothetical protein | 0.0111 | 0.2954 | 0.4227 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.0706 | 0.1503 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0399 | 0.0554 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0651 | 0.0941 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.1483 | 0.3202 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0627 | 0.0905 |
Echinococcus multilocularis | musashi | 0.0055 | 0.1282 | 0.1267 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0165 | 0.4595 | 1 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0635 | 0.0828 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0068 | 0.1675 | 0.2411 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0068 | 0.1675 | 0.1661 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.2954 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0706 | 0.1019 |
Brugia malayi | Cytochrome P450 family protein | 0.0046 | 0.1011 | 0.1379 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0046 | 0.1002 | 0.0986 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0451 | 0.0651 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0022 | 0.028 | 0.0418 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0706 | 0.1019 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0706 | 0.0341 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0068 | 0.1675 | 0.1661 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.2716 | 0.3924 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0013 | 0.0018 | 0.5 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0013 | 0.0018 | 0.0026 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0015 | 0.0092 | 0.0074 |
Schistosoma mansoni | patched 1 | 0.0068 | 0.1675 | 0.1616 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0015 | 0.0092 | 0.0133 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.