Detailed information for compound 165781

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 418.483 | Formula: C22H30N2O6
  • H donors: 3 H acceptors: 4 LogP: 2.83 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C[C@@H](C(=O)N[C@H]1CC(=O)OC1O)NC(=O)COc1ccc2c(c1)CCCC2)C
  • InChi: 1S/C22H30N2O6/c1-13(2)9-17(21(27)24-18-11-20(26)30-22(18)28)23-19(25)12-29-16-8-7-14-5-3-4-6-15(14)10-16/h7-8,10,13,17-18,22,28H,3-6,9,11-12H2,1-2H3,(H,23,25)(H,24,27)/t17-,18-,22?/m0/s1
  • InChiKey: NPETVIGHYFRZJN-KJMDXERQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens caspase 3, apoptosis-related cysteine peptidase Starlite/ChEMBL References
Homo sapiens caspase 8, apoptosis-related cysteine peptidase Starlite/ChEMBL References
Homo sapiens caspase 1, apoptosis-related cysteine peptidase Starlite/ChEMBL References
Homo sapiens caspase 7, apoptosis-related cysteine peptidase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K02187 caspase 3, apoptosis-related cysteine protease, putative Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase Get druggable targets OG5_130238 All targets in OG5_130238
Schistosoma japonicum ko:K04397 caspase 7, apoptosis-related cysteine protease, putative Get druggable targets OG5_130238 All targets in OG5_130238
Schistosoma mansoni caspase-3 (C14 family) Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus multilocularis caspase 3 Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus multilocularis caspase Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus granulosus caspase 3 Get druggable targets OG5_130238 All targets in OG5_130238
Schistosoma mansoni caspase-7 (C14 family) Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus granulosus caspase Get druggable targets OG5_130238 All targets in OG5_130238
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Cell death protein 3 precursor caspase 3, apoptosis-related cysteine peptidase 277 aa 253 aa 38.7 %
Brugia malayi Cell death protein 3 precursor caspase 7, apoptosis-related cysteine peptidase 303 aa 256 aa 37.1 %
Echinococcus granulosus caspase 8 caspase 1, apoptosis-related cysteine peptidase 383 aa 312 aa 26.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi AMP deaminase, putative 0.0352 0.2547 0.2894
Trypanosoma brucei unspecified product 0.0015 0.0003 0.0004
Entamoeba histolytica hypothetical protein 0.002 0.0043 0.0049
Trypanosoma brucei adenosine transporter 2, putative 0.0015 0.0003 0.0004
Plasmodium falciparum metacaspase-like protein 0.0107 0.0697 0.0792
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0961 0.0961
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Echinococcus granulosus adenylate cyclase 9 0.0076 0.0461 0.0524
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.0234 0.0265
Loa Loa (eye worm) Carm1-pending protein 0.0017 0.0023 0.0024
Trypanosoma cruzi adenosine kinase, putative 0.004 0.0197 0.0224
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0063 0.0071
Mycobacterium tuberculosis Conserved protein 0.0107 0.0702 0.0797
Brugia malayi prolyl oligopeptidase family protein 0.0181 0.1258 0.1317
Echinococcus multilocularis caspase 0.0282 0.2021 0.2295
Brugia malayi steroid hormone receptor 0.0031 0.0123 0.0129
Brugia malayi Tachykinin-like peptides receptor 99D 0.0153 0.1044 0.1094
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0142 0.0961 0.1092
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0065 0.0378 0.043
Schistosoma mansoni amine GPCR 0.0153 0.1044 0.1187
Echinococcus multilocularis neuropeptide receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0123 0.0129
Echinococcus multilocularis solute carrier family 28 0.0359 0.2601 0.2954
Trypanosoma brucei NAD+ synthase, putative 0.0017 0.002 0.0023
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0296 0.0336
Brugia malayi neuropeptide F receptor 0.0153 0.1044 0.1094
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.034 0.0387
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0107 0.0702 0.0797
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0056 0.0315 0.0358
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0031 0.0125 0.0142
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0129
Schistosoma mansoni cpg binding protein 0.0032 0.0131 0.0149
Loa Loa (eye worm) melatonin receptor type 1A 0.0153 0.1044 0.1094
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0065 0.0378 0.043
Loa Loa (eye worm) hypothetical protein 0.0026 0.0086 0.009
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0113 0.0747 0.0849
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0104 0.0679 0.0771
Echinococcus granulosus axis inhibition protein axin 0.002 0.0043 0.0049
Echinococcus multilocularis transfer RNA-Lys 0.0073 0.0444 0.0504
Echinococcus multilocularis rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Mycobacterium ulcerans NAD synthetase 0.0017 0.002 0.0023
Plasmodium vivax importin-beta 2, putative 0.003 0.0119 0.0135
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0153 0.1044 0.1094
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0097 0.011
Loa Loa (eye worm) hypothetical protein 0.0438 0.3192 0.3342
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Loa Loa (eye worm) TYRA-2 protein 0.0153 0.1044 0.1094
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0001 0.0001
Brugia malayi Sodium:solute symporter family protein 0.004 0.0194 0.0203
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0085 0.0533 0.0606
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Leishmania major hypothetical protein, unknown function 0.0065 0.0378 0.043
Schistosoma mansoni ribokinase 0.004 0.0197 0.0224
Onchocerca volvulus 0.0081 0.0499 0.0499
Trypanosoma cruzi AMP deaminase, putative 0.0352 0.2547 0.2894
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0153 0.1044 0.1187
Schistosoma mansoni lamin 0.0054 0.0301 0.0342
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0014 0 0.0001
Trypanosoma cruzi metacaspase, putative 0.0107 0.0697 0.0792
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0153 0.1044 0.1094
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.0702 0.0702
Toxoplasma gondii adenosylhomocysteinase, putative 0.1182 0.8803 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0107 0.0697 0.0792
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0026 0.0086 0.0097
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0203 0.023
Schistosoma mansoni single-minded 0.0099 0.0638 0.0724
Loa Loa (eye worm) hypothetical protein 0.0047 0.0243 0.0254
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0059 0.0067
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0107 0.0697 0.0697
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0296 0.0336
Entamoeba histolytica adenosylhomocysteinase, putative 0.1182 0.8803 1
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0053 0.0294 0.0308
Schistosoma mansoni hypothetical protein 0.0041 0.0203 0.023
Leishmania major phosphatidylinositol 3-kinase, putative 0.0104 0.0679 0.0771
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Schistosoma mansoni adenosine kinase 0.0355 0.257 0.2919
Brugia malayi nuclear receptor NHR-88 0.0031 0.0123 0.0129
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0104 0.0679 0.0771
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0153 0.1044 0.1187
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0301 0.0316
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0296 0.3078
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0 0.0001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0001 0.0001
Brugia malayi Adenosine kinase-like 0.0355 0.257 0.2691
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0049 0.0261 0.0297
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0123 0.014
Echinococcus multilocularis g protein coupled receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) DR-78 0.0014 0.0001 0.0001
Schistosoma mansoni coup transcription factor 0.0031 0.0123 0.014
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0092 0.0104
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0156 0.0156
Trypanosoma cruzi Thiopurine S-methyltransferase (TPMT), putative 0.0046 0.024 0.0272
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0142 0.0961 0.1092
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0296 0.0336
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0142 0.0961 0.1092
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0069 0.0409 0.0465
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0123 0.014
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0065 0.0378 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0086 0.0086
Brugia malayi Pre-SET motif family protein 0.0064 0.0374 0.0391
Loa Loa (eye worm) transcription factor SMAD2 0.0243 0.1723 0.1805
Schistosoma mansoni smad1 5 8 and 0.0017 0.0017 0.0019
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0119 0.0135
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0049 0.0051
Echinococcus granulosus caspase 0.0282 0.2021 0.2295
Brugia malayi Adenylyl cyclase protein 0.0076 0.0461 0.0483
Giardia lamblia Hypothetical protein 0.0085 0.0533 0.5546
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0014 0.0015
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0086 0.0097
Trypanosoma brucei Metacaspase-4 0.0107 0.0697 0.0792
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0049 0.0261 0.0261
Entamoeba histolytica hypothetical protein 0.0065 0.0378 0.043
Brugia malayi Death domain containing protein 0.0015 0.0005 0.0005
Onchocerca volvulus Putative pyridoxal kinase 0.004 0.0197 0.0197
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0018 0.002
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.004 0.0197 0.0224
Trypanosoma brucei Thiopurine S-methyltransferase (TPMT), putative 0.0046 0.024 0.0272
Mycobacterium leprae Probable GMP synthase [glutamine-hydrolyzing] GuaA (Glutamine amidotransferase) (GMP synthetase) 0.0023 0.0066 0.0075
Schistosoma mansoni high-affinity choline transporter 0.0364 0.2632 0.299
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0093 0.0592 0.0672
Echinococcus multilocularis g-protein coupled receptor 0.0153 0.1044 0.1187
Trypanosoma cruzi metacaspase 5, putative 0.0107 0.0697 0.0792
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0153 0.1044 0.1187
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0123 0.014
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0142 0.0961 0.1092
Onchocerca volvulus Neuropeptide F receptor homolog 0.0153 0.1044 0.1044
Onchocerca volvulus 0.004 0.0194 0.0194
Schistosoma mansoni zinc finger protein 0.0014 0.0001 0.0001
Trypanosoma brucei ribokinase, putative 0.004 0.0197 0.0224
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0018 0.0026 0.0029
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0137 0.0925 0.0968
Schistosoma mansoni lamin 0.0054 0.0301 0.0342
Brugia malayi Serotonin receptor 0.0153 0.1044 0.1094
Brugia malayi adenosine monophosphate deaminase 0.0352 0.2547 0.2667
Trichomonas vaginalis adenylate cyclase, putative 0.0029 0.011 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0123 0.014
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0043
Echinococcus multilocularis neuropeptide Y receptor 0.0153 0.1044 0.1187
Trypanosoma cruzi adenosine kinase, putative 0.0355 0.257 0.2919
Echinococcus multilocularis dnaJ subfamily B 0.0428 0.3116 0.354
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0589 0.067
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0017 0.0017
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0043 0.0049
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.1182 0.8803 1
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0065 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0589 0.067
Trypanosoma cruzi nucleoside transporter 1, putative 0.0015 0.0003 0.0004
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0097 0.011
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.0702 0.0702
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0063 0.0365 0.0415
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0065 0.0378 0.043
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0065 0.0378 0.043
Echinococcus granulosus equilibrative nucleoside transporter 0.0085 0.0533 0.0606
Trypanosoma cruzi metacaspase, putative 0.0107 0.0697 0.0792
Mycobacterium ulcerans putative regulatory protein 0.0073 0.0444 0.0504
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Echinococcus multilocularis rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0123 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0086 0.0097
Mycobacterium tuberculosis Probable lipase LipD 0.0107 0.0702 0.0797
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0001 0.0001
Brugia malayi nuclear hormone receptor 0.0031 0.0123 0.0129
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0043 0.0045
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0085 0.0533 0.0533
Echinococcus multilocularis adenosylhomocysteinase 0.1182 0.8803 1
Onchocerca volvulus 0.003 0.0118 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0156 0.0163
Trichomonas vaginalis ran, putative 0.0022 0.0059 0.0059
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0017 0.002 0.0023
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0093 0.0097
Echinococcus granulosus g protein coupled receptor 0.0153 0.1044 0.1187
Schistosoma mansoni hypothetical protein 0.0153 0.1044 0.1187
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0296 0.0336
Schistosoma mansoni histamine h1 receptor 0.0153 0.1044 0.1187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0065 0.0378 0.043
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0282 0.2021 0.2295
Brugia malayi G-protein coupled receptor 0.0153 0.1044 0.1094
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0123 0.014
Mycobacterium ulcerans hypothetical protein 0.0107 0.0702 0.0797
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0005 0.0005
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0017 0.0023 0.0026
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.0027 0.0031
Schistosoma mansoni caspase-7 (C14 family) 0.0282 0.2021 0.2295
Trypanosoma cruzi nucleobase transporter, putative 0.0015 0.0003 0.0004
Trypanosoma brucei adenosine transporter 2 0.0015 0.0003 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0123 0.014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0153 0.1044 0.1187
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0142 0.0961 0.1092
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0142 0.0961 0.1092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Leishmania major hypothetical protein, conserved 0.0027 0.0093 0.0105
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0687 0.5067 0.5756
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0065 0.0378 0.043
Mycobacterium tuberculosis Probable GMP synthase [glutamine-hydrolyzing] GuaA (glutamine amidotransferase) (GMP synthetase) 0.0023 0.0066 0.0075
Schistosoma mansoni biogenic amine (5HT) receptor 0.0153 0.1044 0.1187
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0104 0.0679 0.0679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Leishmania major nucleobase transporter 0.0015 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Trichomonas vaginalis guanylate cyclase, putative 0.0029 0.011 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Brugia malayi G protein-coupled receptor F59B2.13 0.0153 0.1044 0.1094
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0065 0.0378 0.043
Schistosoma mansoni neuropeptide receptor 0.0153 0.1044 0.1187
Brugia malayi nuclear receptor RXR 0.0016 0.0014 0.0015
Brugia malayi hypothetical protein 0.0247 0.1756 0.1838
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Brugia malayi hypothetical protein 0.0127 0.0851 0.0891
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0848 0.6284 0.7138
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0086
Loa Loa (eye worm) hypothetical protein 0.0085 0.0533 0.0558
Schistosoma mansoni protein kinase 0.0016 0.0009 0.001
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0015 0.0003 0.0004
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0065 0.0378 0.043
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0031 0.0125 0.0125
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0093 0.0105
Schistosoma mansoni hypothetical protein 0.0065 0.0378 0.043
Schistosoma mansoni inositol transporter 0.004 0.0194 0.022
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0104 0.0679 0.0771
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0123 0.014
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0065 0.0378 0.043
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0065 0.0378 0.043
Onchocerca volvulus 0.0072 0.0437 0.0437
Schistosoma mansoni equilibrative nucleoside transporter 0.0015 0.0003 0.0004
Schistosoma mansoni aryl hydrocarbon receptor 0.0099 0.0638 0.0724
Onchocerca volvulus 0.0014 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0142 0.0961 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0197 0.0206
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0065 0.0378 0.043
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0043 0.0045
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0 0.0001
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0107 0.0697 0.0792
Loa Loa (eye worm) hypothetical protein 0.0063 0.0365 0.0382
Echinococcus multilocularis Ankyrin 0.0015 0.0006 0.0007
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0296 0.031
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0352 0.2547 0.2894
Trypanosoma brucei purine nucleoside transporter 0.0015 0.0003 0.0004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0153 0.1044 0.1187
Leishmania major AMP deaminase, putative 0.0352 0.2547 0.2894
Onchocerca volvulus 0.0054 0.0301 0.0301
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0374 0.0425
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0026 0.0089 0.0094
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.004 0.0197 0.0224
Echinococcus multilocularis neuropeptides capa receptor 0.0153 0.1044 0.1187
Mycobacterium ulcerans methyltransferase 0.0046 0.024 0.0272
Trypanosoma cruzi metacaspase, putative 0.0107 0.0697 0.0792
Echinococcus granulosus AMP deaminase 2 0.0352 0.2547 0.2894
Echinococcus multilocularis rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0104 0.0679 0.0771
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1282 0.955 1
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0049 0.0261 0.0273
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0137 0.0925 0.0925
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0065 0.0378 0.043
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0085 0.0533 0.0533
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0014 0.0016
Echinococcus granulosus smad 0.0017 0.0017 0.0019
Schistosoma mansoni netrin receptor unc5 0.0015 0.0005 0.0006
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0005 0.0006
Entamoeba histolytica nucleoside transporter, putative 0.0015 0.0003 0.0004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0123 0.014
Echinococcus multilocularis somatostatin receptor 0.0153 0.1044 0.1187
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0076 0.0086
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0061 0.0351 0.0399
Entamoeba histolytica AMP deaminase, putative 0.0352 0.2547 0.2894
Onchocerca volvulus 0.0153 0.1044 0.1044
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0123 0.0129
Echinococcus multilocularis lamin dm0 0.0054 0.0301 0.0342
Plasmodium falciparum adenosine deaminase 0.0215 0.1513 0.1719
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0104 0.0679 0.0771
Plasmodium falciparum flap endonuclease 1 0.0027 0.0097 0.011
Echinococcus multilocularis neuropeptide Y receptor 0.0153 0.1044 0.1187
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0156 0.0156
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0142 0.0961 0.1092
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0123 0.014
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0156 0.0156
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0203 0.0212
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0056 0.0315 0.0358
Plasmodium vivax hypothetical protein, conserved 0.0107 0.0697 0.0792
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0015 0.0003 0.0004
Echinococcus granulosus glycyl tRNA synthetase 0.0053 0.0294 0.0334
Echinococcus multilocularis sodium:myo inositol cotransporter 0.004 0.0194 0.022
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0056 0.0315 0.0358
Trypanosoma brucei adenosine kinase, putative 0.0355 0.257 0.2919
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0065 0.0378 0.043
Onchocerca volvulus 0.0153 0.1044 0.1044
Schistosoma mansoni amine GPCR 0.0153 0.1044 0.1187
Giardia lamblia Phosphatidylinositol 4-kinase 0.0113 0.0747 0.7771
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0113 0.0747 0.0849
Entamoeba histolytica AMP deaminase, putative 0.0352 0.2547 0.2894
Echinococcus granulosus g protein coupled receptor 0.0153 0.1044 0.1187
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0352 0.2547 0.2894
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0097 0.011
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0001 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0093 0.0105
Brugia malayi Dopamine receptor protein 1 0.0153 0.1044 0.1094
Brugia malayi MH2 domain containing protein 0.0017 0.0017 0.0017
Giardia lamblia Hypothetical protein 0.0065 0.0378 0.3935
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0129
Toxoplasma gondii kinase, pfkB family protein 0.004 0.0197 0.0224
Leishmania major S-adenosylhomocysteine hydrolase 0.1182 0.8803 1
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0142 0.0961 0.1092
Brugia malayi isocitrate dehydrogenase 0.0017 0.0018 0.0019
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0031 0.0125 0.0142
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0097 0.0624 0.0709
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0059 0.0067
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0017 0.0019
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0123 0.0129
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1082 0.1229
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0181 0.1258 0.1429
Entamoeba histolytica hypothetical protein 0.002 0.0043 0.0049
Leishmania major arginine N-methyltransferase, type I 0.0017 0.0023 0.0026
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0027 0.0031
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0137 0.0925 0.0925
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0129
Schistosoma mansoni smad1 5 8 and 0.0017 0.0017 0.0019
Toxoplasma gondii nucleoside transporter protein 0.0015 0.0003 0.0004
Onchocerca volvulus AMP deaminase 2 homolog 0.0352 0.2547 0.2547
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0153 0.1044 0.1187
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0065 0.0378 0.043
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0048 0.0256 0.0291
Loa Loa (eye worm) Smad1 0.0017 0.0017 0.0017
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0142 0.0961 0.1092
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0296 0.0296
Toxoplasma gondii AMP deaminase 0.0352 0.2547 0.2894
Echinococcus multilocularis neuropeptide receptor 0.0153 0.1044 0.1187
Toxoplasma gondii phosphatidylinositol 4-kinase 0.0049 0.0261 0.0296
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0093 0.0592 0.0593
Trypanosoma brucei protein kinase, putative 0.0054 0.0296 0.0336
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0001 0.0001
Leishmania major protein kinase, putative 0.0038 0.0181 0.0206
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0065 0.0378 0.0378
Schistosoma mansoni adenosylhomocysteinase 0.0732 0.5406 0.6141
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0301 0.0316
Loa Loa (eye worm) hypothetical protein 0.0107 0.0702 0.0735
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0153 0.1048 0.119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Echinococcus granulosus dnaJ subfamily B 0.0428 0.3116 0.354
Echinococcus granulosus neuropeptides capa receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0352 0.2547 0.2894
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0123 0.014
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0015 0.0003 0.0003
Echinococcus granulosus geminin 0.0177 0.1228 0.1394
Loa Loa (eye worm) hypothetical protein 0.0048 0.0256 0.0268
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0001 0.0001
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0029 0.011 0.011
Brugia malayi MH2 domain containing protein 0.0017 0.0017 0.0017
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.0027 0.0031
Plasmodium falciparum AMP deaminase, putative 0.0352 0.2547 0.2894
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0076 0.0076
Onchocerca volvulus 0.0014 0.0001 0.0001
Brugia malayi PAS domain containing protein 0.0099 0.0638 0.0668
Echinococcus granulosus somatostatin receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0064 0.0374 0.0391
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0153 0.1044 0.1187
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0001 0.0001
Brugia malayi Carm1-pending protein 0.0017 0.0023 0.0024
Plasmodium vivax GMP synthetase, putative 0.0063 0.0365 0.0415
Loa Loa (eye worm) hypothetical protein 0.0107 0.0702 0.0735
Entamoeba histolytica protein kinase rad3, putative 0.0065 0.0378 0.043
Loa Loa (eye worm) hypothetical protein 0.0065 0.0378 0.0396
Loa Loa (eye worm) hypothetical protein 0.0033 0.0144 0.0151
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0045 0.0234 0.0245
Brugia malayi nuclear receptor RXR 0.0014 0.0001 0.0001
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0086 0.0097
Echinococcus granulosus adenosine deaminase 0.0215 0.1513 0.1719
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0142 0.0961 0.1092
Trypanosoma cruzi ribokinase, putative 0.004 0.0197 0.0224
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0296 0.0296
Trypanosoma brucei adenosine transporter 2, putative 0.0015 0.0003 0.0004
Entamoeba histolytica kinase, PfkB family 0.004 0.0197 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0123 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0197 0.0197
Schistosoma mansoni axis inhibition protein axin 0.002 0.0043 0.0049
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0065 0.0378 0.043
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0063 0.0071
Echinococcus granulosus neuropeptide receptor 0.0153 0.1044 0.1187
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0089 0.0102
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0092 0.0104
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0104 0.0679 0.0771
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0043 0.0049
Schistosoma mansoni neuropeptide F-like receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0043 0.0045
Onchocerca volvulus 0.0153 0.1044 0.1044
Echinococcus granulosus importin subunit beta 1 0.003 0.0119 0.0135
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0065 0.0378 0.043
Schistosoma mansoni flap endonuclease-1 0.0025 0.0077 0.0088
Echinococcus granulosus serine protein kinase ATM 0.0065 0.0378 0.043
Schistosoma mansoni biogenic amine receptor 0.0153 0.1044 0.1187
Leishmania major GTP-binding protein, putative 0.0022 0.0059 0.0067
Loa Loa (eye worm) hypothetical protein 0.0147 0.0999 0.1046
Brugia malayi Dopamine receptor 0.0153 0.1044 0.1094
Schistosoma mansoni adenosylhomocysteinase 0.0732 0.5406 0.6141
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0015 0.0003 0.0003
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0 0.0001
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0374 0.0425
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.0702 0.0797
Loa Loa (eye worm) G-protein coupled receptor 0.0153 0.1044 0.1094
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0015 0.0003 0.0004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0589 0.0617
Loa Loa (eye worm) prolyl oligopeptidase 0.0181 0.1258 0.1317
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0085 0.0533 0.0558
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0056 0.0315 0.0358
Mycobacterium leprae Probable lipase LipE 0.0107 0.0702 0.0797
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0118 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0017 0.0023 0.0026
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0049 0.0051
Echinococcus granulosus sodium:myo inositol cotransporter 0.004 0.0194 0.022
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0017 0.0023 0.0026
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0065 0.0378 0.043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0015 0.0003 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Schistosoma mansoni regulator of G protein signaling 0.002 0.0043 0.0049
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0104 0.0679 0.0771
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0438 0.3192 0.3626
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0017 0.002 0.0023
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.1182 0.8803 1
Schistosoma mansoni neuropeptide receptor 0.0153 0.1044 0.1187
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0043 0.0049
Mycobacterium tuberculosis Conserved hypothetical protein 0.0065 0.0378 0.043
Echinococcus multilocularis G protein coupled receptor 139 0.0153 0.1044 0.1187
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0697 0.0697
Echinococcus granulosus alpha 1A adrenergic receptor 0.0153 0.1044 0.1187
Echinococcus multilocularis ribokinase 0.004 0.0197 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0049 0.0056
Brugia malayi methionyl-tRNA synthetase 0.0069 0.0409 0.0429
Echinococcus granulosus 7tm_1 domain containing protein 0.0153 0.1044 0.1187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0156 0.0156
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0043 0.0043
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0086 0.0097
Echinococcus multilocularis caspase 8 0.0107 0.0697 0.0792
Loa Loa (eye worm) hypothetical protein 0.0128 0.0857 0.0898
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0085 0.0533 0.0606
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0107 0.0697 0.0697
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0104 0.0679 0.0711
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.004 0.0192 0.0219
Echinococcus granulosus serotonin receptor 0.0153 0.1044 0.1187
Mycobacterium leprae conserved hypothetical protein 0.0107 0.0702 0.0797
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0 0.0001
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0031 0.0125 0.0142
Echinococcus multilocularis high affinity choline transporter 1 0.0364 0.2632 0.299
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0153 0.1044 0.1094
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0093 0.0105
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0098 0.063 0.066
Schistosoma mansoni neuropeptide f receptor 76f 0.0153 0.1044 0.1187
Onchocerca volvulus 0.0438 0.3192 0.3192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trypanosoma brucei AMP deaminase, putative 0.0352 0.2547 0.2894
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0093 0.0105
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0123 0.014
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0017 0.0023 0.0023
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0061 0.0351 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0315 0.0315
Echinococcus granulosus fmrfamide receptor 0.0153 0.1044 0.1187
Plasmodium vivax SET domain protein, putative 0.0064 0.0374 0.0425
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0041 0.0203 0.023
Loa Loa (eye worm) phosphatidylinositol 3 0.0065 0.0378 0.0396
Leishmania major adenosine kinase-like protein 0.004 0.0197 0.0224
Schistosoma mansoni hypothetical protein 0.0428 0.3116 0.354
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0043 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0123 0.0129
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0014 0 0.0001
Schistosoma mansoni hypothetical protein 0.0177 0.1228 0.1394
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.1182 0.8803 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0107 0.0702 0.0735
Brugia malayi hypothetical protein 0.002 0.0043 0.0045
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0001 0.0001
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0093 0.0592 0.0672
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0142 0.0961 1
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Trypanosoma cruzi nucleoside transporter-like, putative 0.0015 0.0003 0.0004
Echinococcus granulosus axis inhibition protein axin 0.002 0.0043 0.0049
Onchocerca volvulus 0.0153 0.1044 0.1044
Schistosoma mansoni alpha glucosidase 0.0035 0.0156 0.0177
Brugia malayi RE15519p 0.0153 0.1044 0.1094
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Onchocerca volvulus 0.005 0.0272 0.0272
Schistosoma mansoni ran 0.0022 0.0059 0.0067
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0296 0.0336
Onchocerca volvulus 0.004 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0332 0.2395 0.2507
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0045
Trichomonas vaginalis adenosine deaminase, putative 0.0215 0.1513 0.1513
Leishmania major ribokinase, putative 0.004 0.0197 0.0224
Onchocerca volvulus 0.0153 0.1044 0.1044
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.005 0.0267 0.0279
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0017 0.0023 0.0026
Brugia malayi prolyl oligopeptidase family protein 0.0061 0.0351 0.0367
Mycobacterium ulcerans GMP synthase 0.0063 0.0365 0.0415
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.004 0.0197 0.0224
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.004 0.0197 0.0224
Mycobacterium tuberculosis Conserved protein 0.0107 0.0702 0.0797
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0156 0.0177
Echinococcus granulosus ribokinase 0.004 0.0197 0.0224
Echinococcus granulosus intermediate filament protein 0.0054 0.0301 0.0342
Brugia malayi hypothetical protein 0.0014 0.0001 0.0001
Toxoplasma gondii 1-phosphatidylinositol 4-kinase 0.0049 0.0261 0.0296
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0153 0.1044 0.1187
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0961 0.0961
Entamoeba histolytica hypothetical protein 0.0023 0.0063 0.0071
Brugia malayi ecdysteroid receptor 0.0031 0.0123 0.0129
Brugia malayi hypothetical protein 0.005 0.0267 0.0279
Loa Loa (eye worm) phosphatidylinositol 3 0.0065 0.0378 0.0396
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0123 0.0123
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0153 0.1044 0.1187
Echinococcus granulosus concentrative Na nucleoside cotransporter 0.0359 0.2601 0.2954
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0043 0.0049
Echinococcus granulosus protein arginine methyltransferase 0.0031 0.0125 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0107 0.0697 0.073
Schistosoma mansoni hypothetical protein 0.0056 0.0315 0.0358
Brugia malayi hypothetical protein 0.0128 0.0857 0.0898
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0153 0.1044 0.1094
Echinococcus multilocularis neuropeptide FF receptor 2 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0053 0.0294 0.0308
Schistosoma mansoni hypothetical protein 0.005 0.0267 0.0303
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0017 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0138 0.0144
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0044 0.0223 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.0378 0.0396
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0374 0.0425
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0153 0.1044 0.1187
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0043 0.0049
Echinococcus granulosus G protein coupled receptor 139 0.0153 0.1044 0.1187
Schistosoma mansoni regulator of G protein signaling 0.002 0.0043 0.0049
Trypanosoma cruzi nucleoside transporter-like, putative 0.0015 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Schistosoma mansoni hypothetical protein 0.0153 0.1044 0.1187
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0001 0.0001
Echinococcus multilocularis protein arginine methyltransferase 0.0031 0.0125 0.0142
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Mycobacterium leprae conserved hypothetical protein 0.0065 0.0378 0.043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Echinococcus multilocularis snurportin 1 0.0322 0.2318 0.2634
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0043 0.0049
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0104 0.0679 0.0711
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0107 0.0697 0.0697
Brugia malayi hypothetical protein 0.0037 0.0172 0.0181
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0137 0.0925 0.1051
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0043 0.0215 0.0215
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0153 0.1044 0.1044
Trichomonas vaginalis ribokinase, putative 0.004 0.0197 0.0197
Entamoeba histolytica adenosine deaminase, putative 0.0215 0.1513 0.1719
Trypanosoma brucei ribokinase, putative 0.004 0.0197 0.0224
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Schistosoma mansoni axis inhibition protein axin 0.002 0.0043 0.0049
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0089 0.0102
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0111 0.0116
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0085 0.0533 0.0533
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0961 0.0961
Echinococcus granulosus neuropeptide receptor A26 0.0153 0.1044 0.1187
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0065 0.0378 0.043
Mycobacterium ulcerans beta-lactamase 0.0107 0.0702 0.0797
Echinococcus multilocularis smad 0.0017 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0043
Leishmania major tagatose-6-phosphate kinase-like protein 0.004 0.0197 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0049 0.0056
Brugia malayi follicle stimulating hormone receptor 0.0153 0.1044 0.1094
Leishmania major adenosine kinase-like protein 0.004 0.0197 0.0224
Echinococcus granulosus death domain containing protein 0.0015 0.0005 0.0006
Trypanosoma brucei adenosine transporter, putative 0.0015 0.0003 0.0004
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0065 0.0378 0.043
Schistosoma mansoni ran 0.0022 0.0059 0.0067
Schistosoma mansoni Smad4 0.0017 0.0017 0.0019
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0097 0.011
Entamoeba histolytica hypothetical protein 0.0048 0.0256 0.0291
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0153 0.1044 0.1187
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0043 0.0049
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0018 0.0026 0.0029
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0 0.0001
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0097 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0123 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0033 0.0138 0.0156
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0961 0.1092
Brugia malayi beta-lactamase 0.0107 0.0702 0.0735
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0017 0.0023 0.0026
Loa Loa (eye worm) phosphatidylinositol 3 0.0113 0.0747 0.0782
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0129
Brugia malayi nuclear hormone receptor 0.0014 0.0001 0.0001
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0017 0.0019
Entamoeba histolytica nucleoside transporter, putative 0.0085 0.0533 0.0606
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0044 0.0223 0.0253
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.0378 0.0396
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0017 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0153 0.1044 0.1187
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0014 0.0016
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0017 0.002 0.0023
Onchocerca volvulus Huntingtin homolog 0.0128 0.0857 0.0857
Brugia malayi hypothetical protein 0.004 0.0197 0.0206
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0107 0.0697 0.0792
Schistosoma mansoni smad1 5 8 and 0.0017 0.0017 0.0019
Brugia malayi Dopamine receptor protein 2 0.0153 0.1044 0.1094
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0049 0.0051
Mycobacterium tuberculosis Probable esterase LipL 0.0107 0.0702 0.0797
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0142 0.0961 0.1092
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0156 0.0156
Onchocerca volvulus 0.0153 0.1044 0.1044
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0142 0.0961 0.1007
Schistosoma mansoni growth hormone secretagogue receptor 0.0153 0.1044 0.1187
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0065 0.0378 0.043
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0061 0.0351 0.0399
Mycobacterium leprae Probable adenosine kinase adk 0.004 0.0197 0.0224
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0063 0.0071
Schistosoma mansoni adenosine deaminase 0.0215 0.1513 0.1719
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0123 0.0129
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0142 0.0961 0.6303
Onchocerca volvulus 0.0315 0.2265 0.2265
Loa Loa (eye worm) phosphatidylinositol 3 0.0065 0.0378 0.0396
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0153 0.1044 0.1187
Schistosoma mansoni biogenic amine (5HT) receptor 0.0153 0.1044 0.1187
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0065 0.0378 0.043
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.0702 0.0702
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0001 0.0001
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0104 0.0679 0.7064
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0044 0.0223 0.0253
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0499 0.0567
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0015
Entamoeba histolytica NAD synthetase, putative 0.0017 0.002 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0296 0.0336
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0017 0.0023 0.0026
Brugia malayi hypothetical protein 0.0033 0.0138 0.0144
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0104 0.0679 0.0771
Schistosoma mansoni microtubule-associated protein tau 0.0722 0.5332 0.6057
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0097 0.011
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0123 0.014
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0063 0.0365 0.0415
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0017 0.0023 0.0026
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Mycobacterium ulcerans adenosine deaminase 0.0215 0.1513 0.1719
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0378 0.043
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0 0.0001
Plasmodium vivax adenosine/AMP deaminase, putative 0.0352 0.2547 0.2894
Schistosoma mansoni caspase-3 (C14 family) 0.0282 0.2021 0.2295
Trypanosoma brucei purine nucleoside transporter 0.0015 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0086 0.0086
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0093 0.0105
Echinococcus granulosus dro:myosuppressin receptor 0.0153 0.1044 0.1187
Echinococcus granulosus protein arginine N methyltransferase 8 0.0031 0.0125 0.0142
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0156 0.0177
Trichomonas vaginalis ribokinase, putative 0.004 0.0197 0.0197
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0181 0.1258 0.1429
Giardia lamblia Rrm3p helicase 0.0056 0.0315 0.3275
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0296 0.0336
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0065 0.0378 0.3935
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0438 0.3192 0.3626
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0352 0.2547 0.2894
Loa Loa (eye worm) phosphatidylinositol 3 0.004 0.0192 0.0202
Loa Loa (eye worm) MH2 domain-containing protein 0.0243 0.1723 0.1805
Echinococcus granulosus neuropeptide Y receptor 0.0153 0.1044 0.1187
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0063 0.0071
Brugia malayi sulfakinin receptor protein 0.0153 0.1044 0.1094
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0153 0.1044 0.1094
Brugia malayi Cell death protein 3 precursor 0.0157 0.1072 0.1122
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0018 0.0019
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.026 0.0296
Echinococcus multilocularis lamin 0.0054 0.0301 0.0342
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0119 0.0135
Echinococcus granulosus single minded 2 0.0077 0.0471 0.0535
Trypanosoma brucei glucosidase, putative 0.0035 0.0156 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0123 0.0129
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0068 0.0406 0.0426
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0123 0.014
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.004 0.0194 0.022
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0029 0.011 0.011
Trypanosoma cruzi GMP synthase [glutamine-hydrolysing] 0.0046 0.0237 0.0269
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0018 0.002
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0123 0.0129
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0045
Onchocerca volvulus 0.0073 0.0444 0.0444
Echinococcus multilocularis dro:myosuppressin receptor 0.0153 0.1044 0.1187
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.0702 0.0797
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0018 0.002
Plasmodium falciparum adenosylhomocysteinase 0.1182 0.8803 1
Schistosoma mansoni regulator of G protein signaling 0.002 0.0043 0.0049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0065 0.0378 0.043
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Echinococcus multilocularis expressed protein 0.039 0.2834 0.322
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.004 0.0194 0.022
Onchocerca volvulus 0.0091 0.058 0.058
Trypanosoma cruzi Thiopurine S-methyltransferase (TPMT), putative 0.0046 0.024 0.0272
Leishmania major metacaspase, putative 0.0107 0.0697 0.0792
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0056 0.0315 0.0358
Trichomonas vaginalis guanylate cyclase, putative 0.0029 0.011 0.011
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0153 0.1044 0.1094
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0113 0.0747 0.0849
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0209 0.147 0.147
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0001 0.0001
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0093 0.0592 0.0673
Echinococcus multilocularis rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Brugia malayi Nucleoside transporter family protein 0.0085 0.0533 0.0558
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0142 0.0961 0.1092
Schistosoma mansoni protein arginine n-methyltransferase 0.0017 0.0023 0.0026
Leishmania major NAD synthase, putative 0.0017 0.002 0.0023
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0059 0.0067
Echinococcus multilocularis adenosine deaminase 0.0215 0.1513 0.1719
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) phosphatidylinositol kinase 0.0438 0.3192 0.3342
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0589 0.067
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0113 0.0747 0.0782
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0123 0.014
Onchocerca volvulus 0.0153 0.1044 0.1044
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0296 0.0336
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0031 0.0125 0.0142
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0065 0.0378 0.043
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0123 0.0123
Leishmania major hypothetical protein, conserved 0.0147 0.0999 0.1134
Echinococcus multilocularis 0.0113 0.0747 0.0849
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0697 0.0697
Loa Loa (eye worm) hypothetical protein 0.0364 0.2632 0.2756
Echinococcus multilocularis apoptotic protease activating factor 1 0.005 0.0267 0.0303
Loa Loa (eye worm) hypothetical protein 0.003 0.0119 0.0125
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0063 0.0365 0.0415
Loa Loa (eye worm) hypothetical protein 0.0054 0.0301 0.0316
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0153 0.1044 0.1187
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0153 0.1044 0.1187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0056 0.0315 0.0358
Schistosoma mansoni nuclear receptor 0.0014 0.0001 0.0001
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0018 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0049 0.0056
Entamoeba histolytica fructokinase, putative 0.004 0.0197 0.0224
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0104 0.0679 0.0711
Brugia malayi putative neuropeptide receptor 0.0153 0.1044 0.1094
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0065 0.0378 0.043
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0014 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0153 0.1044 0.1187
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0296 0.0336
Trypanosoma cruzi GMP synthase, putative 0.0021 0.0048 0.0055
Echinococcus multilocularis musashi 0.0054 0.0301 0.0342
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0123 0.014
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0001 0.0001
Brugia malayi beta-lactamase family protein 0.0107 0.0702 0.0735
Schistosoma mansoni caspase-7 (C14 family) 0.0157 0.1072 0.1218
Trypanosoma brucei metacaspase MCA3 0.0107 0.0697 0.0792
Echinococcus granulosus apoptotic protease activating factor 1 0.005 0.0267 0.0303
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0015 0.0003 0.0004
Echinococcus granulosus g protein coupled receptor 0.0153 0.1044 0.1187
Trypanosoma cruzi adenosine kinase, putative 0.004 0.0197 0.0224
Brugia malayi hypothetical protein 0.0017 0.0021 0.0022
Mycobacterium tuberculosis Probable hydrolase 0.0107 0.0702 0.0797
Trypanosoma cruzi nucleobase transporter, putative 0.0015 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Echinococcus multilocularis adenylate cyclase 9 0.0076 0.0461 0.0524
Onchocerca volvulus Huntingtin homolog 0.0128 0.0857 0.0857
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0111 0.0116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0018 0.0026 0.0029
Brugia malayi hypothetical protein 0.002 0.0043 0.0045
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0045
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0056 0.0315 0.0358
Echinococcus granulosus adenosine kinase 0.0355 0.257 0.2919
Trypanosoma brucei metacaspase 0.0107 0.0697 0.0792
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.004 0.0194 0.022
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0153 0.1044 0.1187
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0014 0.000000026083 0.00000002963
Brugia malayi glycyl-tRNA synthetase 0.0053 0.0294 0.0308
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0065 0.0378 0.043
Echinococcus multilocularis glycyl tRNA synthetase 0.0053 0.0294 0.0334
Toxoplasma gondii ABC1 family protein 0.0107 0.0702 0.0797
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0093 0.0592 0.062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Schistosoma mansoni amine GPCR 0.0153 0.1044 0.1187
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0107 0.0697 0.0697
Loa Loa (eye worm) phosphatidylinositol 3 0.0438 0.3192 0.3342
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0153 0.1044 0.1187
Brugia malayi hypothetical protein 0.0037 0.0172 0.0181
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0065 0.0378 0.043
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0156 0.0177
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0137 0.0925 0.1051
Brugia malayi CXXC zinc finger family protein 0.003 0.0118 0.0124
Schistosoma mansoni GMP synthetase 0.0063 0.0365 0.0415
Loa Loa (eye worm) hypothetical protein 0.0247 0.1756 0.1838
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0086
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0107 0.0697 0.0697
Schistosoma mansoni fkbp-rapamycin associated protein 0.0065 0.0378 0.043
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0153 0.1044 0.1094
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0049 0.0261 0.0297
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0031 0.0125 0.0125
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0014 0.0016
Onchocerca volvulus Ribokinase homolog 0.004 0.0197 0.0197
Leishmania major phosphatidylinositol 4-kinase, putative 0.0113 0.0747 0.0849
Onchocerca volvulus 0.0064 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0017 0.0023 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Schistosoma mansoni neuropeptide receptor 0.0153 0.1044 0.1187
Leishmania major phosphatidylinositol kinase related protein, putative 0.0065 0.0378 0.043
Echinococcus granulosus rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Toxoplasma gondii bicoid-interacting protein BIN3 0.0017 0.0023 0.0026
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0104 0.0679 0.0679
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0086 0.009
Echinococcus multilocularis serine protein kinase ATM 0.0065 0.0378 0.043
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0153 0.1044 0.1187
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0153 0.1044 0.1187
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0093 0.0592 0.0672
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0017 0.002 0.002
Loa Loa (eye worm) adenylyl cyclase 3 0.0076 0.0461 0.0483
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0697 0.0697
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0153 0.1044 0.1187
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0001 0.0001
Mycobacterium tuberculosis Adenosine kinase 0.004 0.0197 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0123 0.0129
Brugia malayi putative neuropeptide receptor NPR1 0.0153 0.1044 0.1094
Trichomonas vaginalis adenosylhomocysteinase, putative 0.1182 0.8803 0.8804
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0142 0.0961 0.1092
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0374 0.0425
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0017 0.002 0.0023
Toxoplasma gondii nucleoside transporter protein 0.0015 0.0003 0.0004
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0097 0.011
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0065 0.0378 0.043
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0301 0.0316
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0044 0.0223 0.0253
Loa Loa (eye worm) hypothetical protein 0.0206 0.1446 0.1514
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0063 0.0071
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0142 0.0961 0.1092
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0438 0.3192 0.3626
Echinococcus multilocularis sex peptide receptor 0.0153 0.1044 0.1187
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0065 0.0378 0.043
Echinococcus multilocularis caspase 2 0.0157 0.1072 0.1218
Loa Loa (eye worm) hypothetical protein 0.0041 0.0203 0.0212
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0045
Echinococcus multilocularis Zinc finger, PHD finger 0.0104 0.0679 0.0771
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0063 0.0071
Onchocerca volvulus 0.0153 0.1044 0.1044
Echinococcus granulosus snurportin 1 0.0322 0.2318 0.2634
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0056 0.0315 0.0358
Echinococcus multilocularis solute carrier family 5 0.004 0.0194 0.022
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0093 0.0592 0.062
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0113 0.0747 0.0849
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0017 0.0023 0.0026
Echinococcus multilocularis geminin 0.0177 0.1228 0.1394
Loa Loa (eye worm) hypothetical protein 0.004 0.0197 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0697 0.0697
Plasmodium vivax hypothetical protein 0.0065 0.0378 0.043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Brugia malayi hypothetical protein 0.0015 0.0003 0.0003
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0296 0.0336
Trypanosoma cruzi nucleoside transporter 1, putative 0.0015 0.0003 0.0004
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0065 0.0378 0.043
Echinococcus multilocularis neuropeptide receptor A26 0.0153 0.1044 0.1187
Trypanosoma cruzi nucleoside transporter 1, putative 0.0015 0.0003 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.0702 0.0797
Brugia malayi Adenosylhomocysteinase 0.1182 0.8803 0.9218
Entamoeba histolytica hypothetical protein 0.002 0.0043 0.0049
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0098 0.063 0.066
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0059 0.0067
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0001 0.0001
Brugia malayi Melatonin receptor type 1A 0.0153 0.1044 0.1094
Echinococcus granulosus neuropeptide FF receptor 2 0.0153 0.1044 0.1187
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0156 0.0156
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0589 0.067
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Echinococcus granulosus tm gpcr rhodopsin 0.0153 0.1044 0.1187
Schistosoma mansoni hypothetical protein 0.0322 0.2318 0.2634
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.0702 0.0702
Echinococcus multilocularis Smad4 0.0017 0.0017 0.0019
Schistosoma mansoni neuropeptide F-like receptor 0.0153 0.1044 0.1187
Leishmania major nucleoside transporter 1, putative 0.0015 0.0003 0.0004
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0104 0.0679 0.0771
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0056 0.0315 0.0358
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0153 0.1044 0.1187
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0296 0.0336
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0006 0.0007
Mycobacterium ulcerans lipase LipD 0.0107 0.0702 0.0797
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0018 0.002
Entamoeba histolytica DNA repair and recombination protein, putative 0.0056 0.0315 0.0358
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0065 0.0378 0.043
Trypanosoma cruzi AMP deaminase, putative 0.0352 0.2547 0.2894
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0015 0.0003 0.0003
Onchocerca volvulus 0.0153 0.1044 0.1044
Echinococcus granulosus rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0961 0.1092
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0043 0.0049
Trypanosoma brucei AMP deaminase, putative 0.0352 0.2547 0.2894
Echinococcus granulosus biogenic amine 5HT receptor 0.0153 0.1044 0.1187
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0107 0.0702 0.0797
Brugia malayi Adenosine/AMP deaminase family protein 0.0215 0.1513 0.1585
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0123 0.0129
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0043 0.0045
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0059 0.0067
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0059 0.0062
Brugia malayi ORL1-like opioid receptor 0.0153 0.1044 0.1094
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0104 0.0679 0.0771
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.0702 0.0797
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0123 0.014
Brugia malayi hypothetical protein 0.0016 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0068 0.0406 0.0426
Onchocerca volvulus 0.0153 0.1044 0.1044
Trypanosoma brucei adenosine transporter 2 0.0015 0.0003 0.0004
Brugia malayi Pre-SET motif family protein 0.1282 0.955 1
Brugia malayi hypothetical protein 0.0014 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trichomonas vaginalis esterase, putative 0.0107 0.0702 0.0702
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0018 0.0026 0.0029
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0123 0.014
Echinococcus multilocularis allatostatin A receptor 0.0153 0.1044 0.1187
Schistosoma mansoni glycyl-tRNA synthetase 0.0053 0.0294 0.0334
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0352 0.2547 0.2894
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0063 0.0071
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0156 0.0156
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0043 0.0049
Echinococcus granulosus beta LACTamase domain containing family member 0.0107 0.0702 0.0797
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0065 0.0378 0.043
Trypanosoma brucei metacaspase MCA2 0.0107 0.0697 0.0792
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0001 0.0001
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0044 0.0223 0.0253
Brugia malayi PXA domain containing protein 0.002 0.0043 0.0045
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Loa Loa (eye worm) hypothetical protein 0.0068 0.0406 0.0426
Entamoeba histolytica Ran family GTPase 0.0022 0.0059 0.0067
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0153 0.1044 0.1187
Schistosoma mansoni cpg binding protein 0.0032 0.0131 0.0149
Schistosoma mansoni biogenic amine receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Trypanosoma cruzi metacaspase, putative 0.0107 0.0697 0.0792
Trypanosoma brucei Thiopurine S-methyltransferase (TPMT), putative 0.0046 0.024 0.0272
Brugia malayi MH2 domain containing protein 0.0243 0.1723 0.1805
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0085 0.0533 0.0533
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0123 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Brugia malayi G protein-coupled receptor 0.0153 0.1044 0.1094
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0015 0.0003 0.0004
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0048 0.0256 0.0291
Schistosoma mansoni adenosine kinase 0.0355 0.257 0.2919
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0076 0.0076
Echinococcus granulosus hypothetical protein 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0153 0.1044 0.1044
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0123 0.014
Schistosoma mansoni adenosylhomocysteinase 0.0732 0.5406 0.6141
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0137 0.0925 0.1051
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0137 0.0925 0.1051
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Plasmodium vivax metacaspase 1, putative 0.0107 0.0697 0.0792
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0093 0.0592 0.0593
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0961 0.0961
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0438 0.3192 0.3626
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0156 0.0177
Echinococcus granulosus sodium:glucose cotransporter 0.004 0.0194 0.022
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0203 0.023
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.0234 0.0265
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0961 0.1092
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0589 0.067
Treponema pallidum adenosine deaminase 0.0215 0.1513 1
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0086 0.0097
Loa Loa (eye worm) hypothetical protein 0.0355 0.257 0.2691
Echinococcus multilocularis G-protein coupled receptor, putative 0.0153 0.1044 0.1187
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0043 0.0049
Brugia malayi hypoxia-induced factor 1 0.0306 0.2201 0.2304
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0104 0.0679 0.0679
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.1756 0.1995
Brugia malayi hypothetical protein 0.0027 0.0093 0.0097
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0104 0.0679 0.0771
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0153 0.1044 0.1187
Echinococcus granulosus Dipeptidyl peptidase 9 0.0061 0.0351 0.0399
Schistosoma mansoni survival motor neuron protein 0.005 0.0272 0.0309
Schistosoma mansoni voltage-gated potassium channel 0.0014 0 0.0001
Loa Loa (eye worm) neuropeptide F receptor 0.0153 0.1044 0.1094
Loa Loa (eye worm) hypothetical protein 0.0065 0.0378 0.0396
Chlamydia trachomatis methionine--tRNA ligase 0.0069 0.0409 0.3858
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.0069 0.0409 0.0465
Echinococcus granulosus neuropeptides capa receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0215 0.1513 0.1585
Trypanosoma brucei unspecified product 0.0015 0.0003 0.0004
Echinococcus multilocularis orexin receptor type 2 0.0153 0.1044 0.1187
Brugia malayi AKH receptor 0.0153 0.1044 0.1094
Trichomonas vaginalis set domain proteins, putative 0.1341 0.9999 1
Echinococcus granulosus caspase 8 0.0107 0.0697 0.0792
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0153 0.1044 0.1187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0153 0.1044 0.1187
Toxoplasma gondii target of rapamycin (TOR), putative 0.0065 0.0378 0.043
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Onchocerca volvulus 0.005 0.0267 0.0267
Brugia malayi Ribokinase 0.004 0.0197 0.0206
Loa Loa (eye worm) hypothetical protein 0.0107 0.0702 0.0735
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0137 0.0925 0.1051
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0018 0.0026 0.0029
Trypanosoma brucei adenosine transporter 2, putative 0.0015 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0123 0.0129
Echinococcus multilocularis caspase 3 0.0176 0.1215 0.1381
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0142 0.0961 0.1092
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.1182 0.8803 1
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0296 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trypanosoma brucei AMP deaminase, putative 0.0352 0.2547 0.2894
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0065 0.0378 0.043
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.1082 0.1229
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0153 0.1044 0.1094
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0043 0.0049
Schistosoma mansoni adenosylhomocysteinase 0.1182 0.8803 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.04 0.0455
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0371 0.2689 0.2689
Brugia malayi neuropeptide F receptor 0.0153 0.1044 0.1094
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0063 0.0071
Echinococcus multilocularis adenosine kinase 0.0355 0.257 0.2919
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.1182 0.8803 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0018 0.0026 0.0029
Echinococcus granulosus lamin 0.0054 0.0301 0.0342
Loa Loa (eye worm) AMP deaminase 0.0352 0.2547 0.2667
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0018 0.002
Trypanosoma cruzi AMP deaminase 2, putative 0.0147 0.0999 0.1134
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.1082 0.1133
Onchocerca volvulus 0.0153 0.1044 0.1044
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0153 0.1044 0.1187
Trypanosoma brucei nucleoside transporter 1, putative 0.0015 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0104 0.0679 0.0771
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0017 0.0023 0.0026
Trypanosoma brucei adenosine kinase, putative 0.0355 0.257 0.2919
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0472 0.0536
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.0215 0.1513 0.1719
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0374 0.0425
Brugia malayi conserved hypotetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0123 0.0129
Giardia lamblia NH3-dependent NAD+ synthetase 0.0017 0.002 0.021
Schistosoma mansoni hypothetical protein 0.005 0.0272 0.0309
Onchocerca volvulus 0.0026 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.004 0.0194 0.0203
Echinococcus granulosus allatostatin A receptor 0.0153 0.1044 0.1187
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0153 0.1044 0.1094
Loa Loa (eye worm) hypothetical protein 0.0128 0.0857 0.0898
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0001 0.0001
Schistosoma mansoni alpha-glucosidase 0.0136 0.0916 0.1041
Onchocerca volvulus Cell death protein 3 homolog 0.0157 0.1072 0.1072
Echinococcus granulosus flap endonuclease 1 0.0027 0.0097 0.011
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0296 0.0336
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0123 0.0129
Trypanosoma cruzi AMP deaminase, putative 0.0352 0.2547 0.2894
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0065 0.0378 0.043
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0001 0.0001
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0065 0.0378 0.043
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0153 0.1044 0.1187
Trypanosoma cruzi adenosine kinase, putative 0.0355 0.257 0.2919
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Onchocerca volvulus 0.0438 0.3192 0.3192
Echinococcus granulosus sex peptide receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0045
Onchocerca volvulus 0.0153 0.1044 0.1044
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Trypanosoma cruzi AMP deaminase, putative 0.0352 0.2547 0.2894
Schistosoma mansoni neuropeptide receptor 0.0153 0.1044 0.1187
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0104 0.0679 0.0771
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0153 0.1044 0.1187
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0065 0.0378 0.043
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0104 0.0679 0.0771
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0043 0.0045
Echinococcus multilocularis fmrfamide receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Trichomonas vaginalis ribokinase, putative 0.004 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0043 0.0045
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0045 0.0234 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0123 0.0129
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0123 0.014
Schistosoma mansoni hypothetical protein 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0107 0.0702 0.0735
Trypanosoma brucei hypothetical protein, conserved 0.0107 0.0702 0.0797
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0001 0.0001
Leishmania major putative PfkB family sugar kinase 0.004 0.0197 0.0224
Onchocerca volvulus 0.0031 0.0123 0.0123
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0123 0.014
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0352 0.2547 0.2894
Brugia malayi RNA, U transporter 1 0.0086 0.0538 0.0563
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0153 0.1044 0.1187
Echinococcus granulosus peptide allatostatin:somatostatin 0.0153 0.1044 0.1187
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0113 0.0747 0.0849
Loa Loa (eye worm) RGS-3 protein 0.002 0.0043 0.0045
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0104 0.0679 0.0771
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0061 0.0351 0.0399
Brugia malayi hypothetical protein 0.0047 0.0243 0.0254
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0123 0.014
Brugia malayi Smad1 0.0017 0.0017 0.0017
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0181 0.1258 0.1429
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Plasmodium falciparum importin beta, putative 0.003 0.0119 0.0135
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0104 0.0679 0.0679
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.004 0.0192 0.0219
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0104 0.0679 0.0679
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0097 0.0102
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0005 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Trypanosoma brucei nucleoside transporter 1, putative 0.0015 0.0003 0.0004
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0123 0.014
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0018 0.002
Brugia malayi Serotonin receptor 0.0153 0.1044 0.1094
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0017 0.0023 0.0026
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0018 0.0019
Brugia malayi hypothetical protein 0.0016 0.0014 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0153 0.1044 0.1187
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0029 0.011 0.011
Brugia malayi PXA domain containing protein 0.002 0.0043 0.0045
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0043 0.0049
Echinococcus granulosus expressed protein 0.039 0.2834 0.322
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0018 0.0026 0.0029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0005 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0153 0.1044 0.1187
Trichomonas vaginalis adenosine deaminase, putative 0.0215 0.1513 0.1513
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0104 0.0679 0.0679
Loa Loa (eye worm) hypothetical protein 0.0104 0.0679 0.0711
Echinococcus granulosus adenosylhomocysteinase 0.1182 0.8803 1
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.004 0.0197 0.0224
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0142 0.0961 0.1092
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0031 0.0125 0.0125
Brugia malayi MH1 domain containing protein 0.0017 0.0017 0.0017
Echinococcus granulosus Ankyrin 0.0015 0.0006 0.0007
Brugia malayi Protein arginine N-methyltransferase 0.0017 0.0023 0.0024
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0153 0.1044 0.1187
Leishmania major hypothetical protein, conserved 0.0046 0.024 0.0272
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0499 0.0523
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0499 0.0567
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0031 0.0125 0.0142
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0048 0.0256 0.0291
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0142 0.0961 0.1092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0123 0.0129
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.1756 0.1995
Trypanosoma cruzi NAD+ synthase, putative 0.0017 0.002 0.0023
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0123 0.0129
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0053 0.0294 0.0308
Echinococcus multilocularis sodium:glucose cotransporter 2 0.004 0.0194 0.022
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0104 0.0679 0.0679
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0005 0.0006
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0374 0.0425
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0349 0.0396
Schistosoma mansoni regulator of G protein signaling 0.002 0.0043 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0697 0.0697
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0097 0.1009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0153 0.1044 0.1187
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0153 0.1044 0.1187
Onchocerca volvulus 0.0107 0.0702 0.0702
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trypanosoma cruzi metacaspase 5, putative 0.0107 0.0697 0.0792
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Plasmodium vivax hypothetical protein, conserved 0.0107 0.0702 0.0797
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0045
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0153 0.1044 0.1094
Giardia lamblia Ribokinase 0.004 0.0197 0.2049
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.007 0.0422 0.0479
Brugia malayi hypothetical protein 0.0332 0.2395 0.2507
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0017 0.002 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0374 0.0425
Wolbachia endosymbiont of Brugia malayi GMP synthase 0.0046 0.0237 0.1936
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0018 0.002
Echinococcus multilocularis g protein coupled receptor 0.0153 0.1044 0.1187
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0061 0.0351 0.0399
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0589 0.067
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0043 0.0045
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0104 0.0679 0.0771
Leishmania major nucleobase transporter 0.0015 0.0003 0.0004
Brugia malayi Importin beta-1 subunit 0.003 0.0119 0.0125
Entamoeba histolytica adenosine deaminase, putative 0.0215 0.1513 0.1719
Echinococcus granulosus methyltransferase protein 5 0.0017 0.0023 0.0026
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0027 0.0031
Onchocerca volvulus 0.0076 0.0461 0.0461
Schistosoma mansoni methionine-tRNA synthetase 0.0069 0.0409 0.0465
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0104 0.0679 0.0771
Echinococcus granulosus caspase 3 0.0176 0.1215 0.1381
Echinococcus granulosus sodium:glucose cotransporter 2 0.004 0.0194 0.022
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0043 0.0049
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Mycobacterium ulcerans esterase/lipase LipP 0.0107 0.0702 0.0797
Schistosoma mansoni nuclear receptor 0.0014 0.0001 0.0001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0107 0.0702 0.0735
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0107 0.0697 0.0792
Trypanosoma cruzi hypothetical protein 0.0405 0.2945 0.3345
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0026 0.0086 0.0255
Brugia malayi MAP kinase sur-1 0.0054 0.0296 0.031
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0282 0.2021 0.2295
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0378 0.0378
Echinococcus multilocularis sodium:nucleoside cotransporter 2 0.0234 0.1658 0.1884
Leishmania major arginine N-methyltransferase-like protein 0.0031 0.0125 0.0142
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0065 0.0378 0.043
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0156 0.0177
Leishmania major tagatose-6-phosphate kinase-like protein 0.004 0.0197 0.0224
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0015
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0322 0.2318 0.2427
Loa Loa (eye worm) hypothetical protein 0.0033 0.0138 0.0144
Echinococcus granulosus high affinity choline transporter 1 0.0364 0.2632 0.299
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0697 0.0697
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0018 0.002
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0001 0.0001
Echinococcus granulosus neuropeptide s receptor 0.0153 0.1044 0.1187
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0043 0.0049
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0961 0.0961
Loa Loa (eye worm) hypothetical protein 0.0157 0.1072 0.1122
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0296 0.0296
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0093 0.0105
Brugia malayi larval opioid receptor 0.0153 0.1044 0.1094
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0104 0.0679 0.0679
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0 0.0001
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0031 0.0125 0.0142
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0438 0.3192 0.3342
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0104 0.0679 0.0771
Plasmodium falciparum metacaspase 1 0.0107 0.0697 0.0792
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0059 0.0067
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.1082 0.1133
Brugia malayi GnHR receptor homolog 0.0153 0.1044 0.1094
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0123 0.014
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0061 0.0351 0.0399
Echinococcus granulosus Na+ dependent nucleoside transporter 0.0359 0.2601 0.2954
Brugia malayi hypothetical protein 0.0048 0.0256 0.0268
Schistosoma mansoni importin beta-1 0.003 0.0119 0.0135
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0156 0.0177
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0215 0.1513 0.1719
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0058 0.0327 0.0342
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0031 0.0125 0.0142
Trypanosoma cruzi NAD+ synthase, putative 0.0017 0.002 0.0023
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0043 0.0049
Schistosoma mansoni cpg binding protein 0.003 0.0118 0.0134
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0107 0.0697 0.0697
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0107 0.0702 0.0735
Loa Loa (eye worm) hypothetical protein 0.0069 0.0409 0.0429
Echinococcus multilocularis importin subunit beta 1 0.003 0.0119 0.0135
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.000000026083 0.00000002963
Loa Loa (eye worm) hypothetical protein 0.0076 0.0461 0.0483
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0065 0.0378 0.043
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0043
Leishmania major importin beta-1 subunit, putative 0.0024 0.0076 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Loa Loa (eye worm) neuropeptide F receptor 0.0153 0.1044 0.1094
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0203 0.0212
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0041 0.0203 0.0212
Echinococcus multilocularis AMP deaminase 2 0.0352 0.2547 0.2894
Mycobacterium tuberculosis Ribokinase RbsK 0.004 0.0197 0.0224
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0153 0.1044 0.1187
Schistosoma mansoni hypothetical protein 0.0153 0.1044 0.1187
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0123 0.014
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0156 0.0177
Echinococcus granulosus 7TM GPCR rhodopsin 0.0153 0.1044 0.1187
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0093 0.0592 0.0673
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0272 0.0285
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0181 0.1258 0.1258
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Schistosoma mansoni AMP deaminase 0.0352 0.2547 0.2894
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0049 0.0056
Entamoeba histolytica hypothetical protein 0.0065 0.0378 0.043
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0107 0.0702 0.0797
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0065 0.0378 0.043
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0043
Entamoeba histolytica nucleoside transporter, putative 0.0015 0.0003 0.0004
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0001 0.0001
Onchocerca volvulus Adenosine deaminase homolog 0.0215 0.1513 0.1513
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Entamoeba histolytica hypothetical protein 0.0065 0.0378 0.043
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0153 0.1044 0.1187
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0107 0.0697 0.0697
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0026 0.0086 0.0097
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Loa Loa (eye worm) phosphatidylinositol 3 0.0104 0.0679 0.0711
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0153 0.1044 0.1187
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Onchocerca volvulus 0.0107 0.0702 0.0702
Echinococcus granulosus protein arginine N methyltransferase 7 0.0017 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0059 0.0067
Onchocerca volvulus 0.0153 0.1044 0.1044
Loa Loa (eye worm) hypothetical protein 0.0085 0.0533 0.0558
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0061 0.0351 0.0399
Brugia malayi intermediate filament protein 0.0054 0.0301 0.0316
Brugia malayi nuclear receptor NHR-67 0.0014 0.0001 0.0001
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0137 0.0925 0.1051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Brugia malayi beta-lactamase family protein 0.0107 0.0702 0.0735
Onchocerca volvulus 0.0153 0.1044 0.1044
Echinococcus granulosus solute carrier family 28 0.0359 0.2601 0.2954
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0059 0.0067
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0048 0.0256 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0123 0.0129
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0063 0.0071
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0044 0.0223 0.0234
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0123 0.014
Mycobacterium ulcerans carbohydrate kinase CbhK 0.004 0.0197 0.0224
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.0215 0.1513 0.1719
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0085 0.0533 0.0606
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0123 0.014
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0107 0.0697 0.0697
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0092 0.0104
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0063 0.0365 0.0415
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0123 0.014
Trypanosoma brucei adenosine transporter 2, putative 0.0015 0.0003 0.0004
Brugia malayi Protein kinase domain containing protein 0.0016 0.0011 0.0012
Schistosoma mansoni sodium/solute symporter 0.004 0.0194 0.022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0123 0.0129
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.0378 0.0396
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0027 0.0031
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0001 0.0001
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0093 0.0105
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0153 0.1044 0.1187
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0113 0.0747 0.0849
Schistosoma mansoni adenosylhomocysteinase 0.0732 0.5406 0.6141
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0014 0 0.0001
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0005 0.0005
Schistosoma mansoni amine GPCR 0.0153 0.1044 0.1187
Schistosoma mansoni hypothetical protein 0.0177 0.1228 0.1394
Echinococcus granulosus rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Schistosoma mansoni opsin-like receptor 0.0153 0.1044 0.1187
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0014 0 0.0001
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0015 0.0003 0.0003
Echinococcus granulosus neuropeptide receptor 0.0153 0.1044 0.1187
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0142 0.0961 0.1092
Loa Loa (eye worm) hypothetical protein 0.0093 0.0592 0.062
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0156 0.0156
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0119 0.0135
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.1182 0.8803 1
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0589 0.0617
Echinococcus granulosus cpg binding protein 0.0032 0.0131 0.0149
Loa Loa (eye worm) phosphatidylinositol 3 0.0438 0.3192 0.3342
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.000000026083 0.00000002963
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0063 0.0285
Brugia malayi GMP synthase 0.0063 0.0365 0.0382
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0053 0.0294 0.0308
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0113 0.0747 0.0849
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Leishmania major nucleoside transporter 1, putative 0.0015 0.0003 0.0004
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0142 0.0961 0.1092
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0017 0.0023 0.0023
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0123 0.014
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0142 0.0961 0.1092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0017 0.0019
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0043 0.0049
Leishmania major phosphatidylinositol 3-kinase, putative 0.0065 0.0378 0.043
Echinococcus granulosus rhodopsin orphan GPCR 0.0153 0.1044 0.1187
Trypanosoma brucei metacaspase 5, putative 0.0107 0.0697 0.0792
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0472 0.0536
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0374 0.0425
Leishmania major adenosine kinase, putative 0.0355 0.257 0.2919
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.0702 0.0702
Brugia malayi nuclear receptor NHR-88 0.0014 0.0001 0.0001
Schistosoma mansoni adenosine deaminase-related 0.0215 0.1513 0.1719
Brugia malayi bHLH-PAS transcription factor 0.0073 0.0444 0.0465
Leishmania major phosphatidylinositol kinase, putative 0.0065 0.0378 0.043
Schistosoma mansoni hypothetical protein 0.0033 0.0138 0.0156
Loa Loa (eye worm) adenosylhomocysteinase 0.1182 0.8803 0.9218
Brugia malayi hypothetical protein 0.0085 0.0533 0.0558
Mycobacterium tuberculosis Conserved protein 0.0046 0.024 0.0272
Entamoeba histolytica hypothetical protein 0.0104 0.0679 0.0771
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0001 0.0001
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0018 0.002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0153 0.1044 0.1187
Entamoeba histolytica hypothetical protein 0.0024 0.0076 0.0086
Schistosoma mansoni smad 0.0017 0.0017 0.0019
Giardia lamblia GTOR 0.0065 0.0378 0.3935
Echinococcus granulosus orexin receptor type 2 0.0153 0.1044 0.1187
Trypanosoma brucei adenosine transporter 2, putative 0.0015 0.0003 0.0004
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0142 0.0961 0.1092
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0065 0.0378 0.043
Schistosoma mansoni alpha-glucosidase 0.0136 0.0916 0.1041
Brugia malayi MH1 domain containing protein 0.0017 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0065 0.0378 0.043
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0156 0.0163
Trichomonas vaginalis adenosylhomocysteinase, putative 0.1182 0.8803 0.8804
Toxoplasma gondii nucleoside transporter protein 0.0015 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0068 0.0406 0.0426
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0123 0.0129
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0153 0.1044 0.1187
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0065 0.0378 0.043
Onchocerca volvulus 0.0153 0.1044 0.1044
Schistosoma mansoni intermediate filament proteins 0.0054 0.0301 0.0342
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0129
Schistosoma mansoni myosin xvIII 0.0153 0.1044 0.1187
Mycobacterium tuberculosis Conserved protein 0.0107 0.0702 0.0797
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Echinococcus granulosus Smad4 0.0017 0.0017 0.0019
Echinococcus multilocularis serotonin receptor 0.0153 0.1044 0.1187
Entamoeba histolytica ribokinase, putative 0.004 0.0197 0.0224
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0049 0.0056
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Echinococcus multilocularis beta LACTamase domain containing family member 0.0107 0.0702 0.0797
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0156 0.0177
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0065 0.0378 0.043
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.026 0.0296
Schistosoma mansoni alpha-1 adrenergic receptor 0.0153 0.1044 0.1187
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0043 0.0049
Onchocerca volvulus 0.0147 0.0999 0.0999
Mycobacterium ulcerans fructokinase, PfkB 0.004 0.0197 0.0224
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0001 0.0001
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0296 0.0336
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0104 0.0679 0.0771
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0018 0.002
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0142 0.0961 0.1092
Echinococcus granulosus solute carrier family 5 0.004 0.0194 0.022
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0014 0.0016
Trypanosoma cruzi target of rapamycin kinase 3 0.0065 0.0378 0.043
Echinococcus granulosus g-protein coupled receptor 0.0153 0.1044 0.1187
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0086 0.0086
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0001 0.0001
Schistosoma mansoni biogenic amine receptor 0.0153 0.1044 0.1187
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypoxia-induced factor 1 0.0306 0.2201 0.2304
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0029 0.011 0.011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0438 0.3192 0.3342
Leishmania major adenine aminohydrolase 0.0215 0.1513 0.1719
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0017 0.0023 0.0026
Echinococcus granulosus tachykinin peptides receptor 99D 0.0153 0.1044 0.1187
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0018 0.002
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0092 0.0104
Echinococcus granulosus tm gpcr rhodopsin 0.0153 0.1044 0.1187
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0 0.0001
Loa Loa (eye worm) beta-lactamase 0.0107 0.0702 0.0735
Brugia malayi Flap endonuclease-1 0.0027 0.0097 0.0102
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0093 0.0592 0.6157
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0215 0.1513 0.1719
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0097 0.011
Echinococcus granulosus microtubule associated protein 2 0.0722 0.5332 0.6057
Echinococcus granulosus lamin dm0 0.0054 0.0301 0.0342
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.0378 0.0396
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0043 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Schistosoma mansoni hypothetical protein 0.0054 0.0299 0.034
Trypanosoma brucei adenosine transporter, putative 0.0015 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0123 0.0129
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0018 0.002
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0018 0.002
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0142 0.0961 0.1092
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0142 0.0961 0.1092
Plasmodium vivax adenosine deaminase, putative 0.0215 0.1513 0.1719
Echinococcus multilocularis serotonin receptor 0.0153 0.1044 0.1187
Mycobacterium leprae Possible regulatory protein 0.0026 0.0086 0.0097
Toxoplasma gondii kinase, pfkB family protein 0.0355 0.257 0.2919
Brugia malayi hypothetical protein 0.0153 0.1044 0.1094
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0018 0.002
Onchocerca volvulus 0.0107 0.0702 0.0702
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0043
Mycobacterium tuberculosis Probable lipase LipE 0.0107 0.0702 0.0797
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0015 0.0003 0.0004
Brugia malayi tailless protein 0.0014 0.0001 0.0001
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0015 0.0003 0.0003
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0104 0.0679 0.0771
Echinococcus multilocularis microtubule associated protein 2 0.0722 0.5332 0.6057
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) hypothetical protein 0.0031 0.0123 0.0129
Onchocerca volvulus 0.0054 0.0301 0.0301
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0142 0.0961 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0499 0.0523
Treponema pallidum methionyl-tRNA synthetase 0.0069 0.0409 0.2607
Echinococcus granulosus biogenic amine 5HT receptor 0.0153 0.1044 0.1187
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0123 0.014
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0104 0.0679 0.0679
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0063 0.0071
Schistosoma mansoni inositol transporter 0.004 0.0194 0.022
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0059 0.0614
Entamoeba histolytica hypothetical protein, conserved 0.0056 0.0315 0.0358
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0065 0.0378 0.043
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0093 0.0592 0.0672
Schistosoma mansoni regulator of G protein signaling 0.002 0.0043 0.0049
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0017 0.002 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Schistosoma mansoni opsin-like receptor 0.0153 0.1044 0.1187
Loa Loa (eye worm) STAT protein 0.0138 0.0929 0.0972
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1082 0.1229
Brugia malayi G-protein coupled receptor 0.0153 0.1044 0.1094
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0142 0.0961 0.1092
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.0069 0.0409 0.0465
Leishmania major protein kinase, putative 0.0027 0.0092 0.0104
Echinococcus multilocularis fmrfamide receptor 0.0153 0.1044 0.1187
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0018 0.0027 0.0028
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0123 0.014
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0438 0.3192 0.3626
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0029 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0332 0.2393 0.2505
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0015
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0137 0.0925 0.0968
Schistosoma mansoni adenoreceptor 0.0153 0.1044 0.1187
Toxoplasma gondii FATC domain-containing protein 0.0065 0.0378 0.043
Brugia malayi STAT protein, DNA binding domain containing protein 0.0138 0.0929 0.0972
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0137 0.0925 0.1051
Echinococcus multilocularis neuropeptide s receptor 0.0153 0.1044 0.1187
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0107 0.0697 0.073
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0137 0.0925 0.1051
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.1182 0.8803 1
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0015 0.0003 0.0004
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0017 0.0017
Loa Loa (eye worm) G-protein coupled receptor 0.0153 0.1044 0.1094
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0041 0.0203 0.023
Loa Loa (eye worm) hypothetical protein 0.0205 0.144 0.1508
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0059 0.0062
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0063 0.0365 0.0415
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0104 0.0679 0.0771
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0589 0.067
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0085 0.0533 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0378 0.0378
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0018 0.0026 0.0029
Echinococcus granulosus caspase 2 0.0157 0.1072 0.1218
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0107 0.0697 0.0697
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0107 0.0702 0.0797
Trypanosoma cruzi nucleobase transporter, putative 0.0015 0.0003 0.0004
Brugia malayi Uncoordinated protein 44 0.0015 0.0005 0.0005
Leishmania major hypothetical protein, conserved 0.0107 0.0702 0.0797
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0085 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0028
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0043 0.0049
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0065 0.0378 0.043
Loa Loa (eye worm) hypothetical protein 0.0153 0.1044 0.1094
Brugia malayi GH02984p 0.0364 0.2632 0.2756
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0076 0.0461 0.0461
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0063 0.0365 0.0415
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0061 0.0351 0.0399
Loa Loa (eye worm) hypothetical protein 0.0107 0.0702 0.0735
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0017 0.0019
Schistosoma mansoni opsin-like receptor 0.0153 0.1044 0.1187
Leishmania major hypothetical protein, conserved 0.0065 0.0378 0.043
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0123 0.0129
Brugia malayi ecdysone receptor 0.0014 0.0001 0.0001
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0005 0.0006
Onchocerca volvulus 0.0153 0.1044 0.1044
Echinococcus multilocularis cpg binding protein 0.0032 0.0131 0.0149
Echinococcus multilocularis concentrative Na+ nucleoside cotransporter 0.0359 0.2601 0.2954
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.1182 0.8803 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0156 0.0156
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0499 0.0567

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.162 uM Inhibitory concentration against caspase-3 ChEMBL. 12270185
IC50 (binding) = 0.162 uM Inhibitory concentration against caspase-3 ChEMBL. 12270185
IC50 (binding) = 2.31 uM Inhibitory concentration against caspase-7 ChEMBL. 12270185
IC50 (binding) = 2.31 uM Inhibitory concentration against caspase-7 ChEMBL. 12270185
IC50 (binding) = 2.57 uM Inhibition of caspase-1 ChEMBL. 12270185
IC50 (binding) = 2.57 uM Inhibition of caspase-1 ChEMBL. 12270185
IC50 (binding) = 4.95 uM Inhibitory concentration against caspase-8 ChEMBL. 12270185
IC50 (binding) = 4.95 uM Inhibitory concentration against caspase-8 ChEMBL. 12270185
IC50 (binding) = 28.6 uM Inhibitory concentration required against caspase-6 ChEMBL. 12270185
IC50 (binding) = 28.6 uM Inhibitory concentration required against caspase-6 ChEMBL. 12270185

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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