Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | histamine receptor H4 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0093 | 0.5 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0093 | 0.5 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0093 | 0.5 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0093 | 0.5 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0093 | 0.5 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0093 | 0.5 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0093 | 0.5 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0093 | 0.5 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0093 | 0.5 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0093 | 0.5 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0093 | 0.5 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0093 | 0.5 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0093 | 0.5 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0093 | 0.5 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0093 | 0.5 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0093 | 0.5 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.5 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0093 | 0.5 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0093 | 0.5 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0093 | 0.5 | 0.5 | |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0093 | 0.5 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0093 | 0.5 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0093 | 0.5 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0093 | 0.5 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0093 | 0.5 | 0.5 |
Brugia malayi | steroid hormone receptor | 0.0093 | 0.5 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0093 | 0.5 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0093 | 0.5 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0093 | 0.5 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0093 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.