Detailed information for compound 1659736

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 598.724 | Formula: C34H46O9
  • H donors: 1 H acceptors: 5 LogP: 5.14 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)CCCCCCC(=O)O[C@H]1CC[C@]2([C@@H](C1)CC[C@@H]1[C@@H]2CC[C@]2([C@]31O[C@@H]3[C@@H]([C@@H]2c1ccc(=O)oc1)OC(=O)C)C)C
  • InChi: 1S/C34H46O9/c1-20(35)41-30-29(21-10-13-27(38)40-19-21)33(3)17-15-24-25(34(33)31(30)43-34)12-11-22-18-23(14-16-32(22,24)2)42-28(39)9-7-5-4-6-8-26(36)37/h10,13,19,22-25,29-31H,4-9,11-12,14-18H2,1-3H3,(H,36,37)/t22-,23+,24+,25-,29+,30-,31-,32+,33-,34-/m1/s1
  • InChiKey: WNMNOTRKSZQFML-NDESRDLBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0726 0.7358 0.9777
Brugia malayi hypothetical protein 0.0016 0.0091 0.0086
Schistosoma mansoni retinoic acid receptor RXR 0.0035 0.0278 0.0415
Brugia malayi tailless protein 0.0016 0.0091 0.0086
Loa Loa (eye worm) hypothetical protein 0.0012 0.0046 0.0025
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.0334
Loa Loa (eye worm) hypothetical protein 0.0064 0.0583 0.074
Schistosoma mansoni ets-related 0.0229 0.2262 0.3458
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0035 0.0278 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0046 0.9999
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0046 0.9999
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0036 0.0044
Echinococcus granulosus tar DNA binding protein 0.0077 0.0711 0.1079
Echinococcus granulosus carbonic anhydrase 0.035 0.3501 0.5357
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0278 0.0415
Brugia malayi Ets-domain containing protein 0.0075 0.0694 0.0891
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.0111
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0036 0.0028
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.012 0.0173
Brugia malayi Pax transcription activation domain interacting protein 0.0012 0.0046 0.0027
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0035 0.0278 0.0415
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0035 0.0278 0.0415
Brugia malayi hypothetical protein 0.0018 0.0111 0.0113
Schistosoma mansoni topbp1 0.0012 0.0046 0.006
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0091 0.0058
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0259 0.0309
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0035 0.0278 0.0415
Echinococcus multilocularis ecdysone induced protein 78C 0.0035 0.0278 0.0271
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0035 0.0278 0.0334
Echinococcus multilocularis protein C ets 2 0.0011 0.0036 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0091 0.0128
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.035 0.3501 0.4634
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.035 0.3501 0.4634
Brugia malayi hypothetical protein 0.0012 0.0046 0.0027
Schistosoma mansoni cpg binding protein 0.0035 0.0278 0.0416
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0278 0.0335
Echinococcus multilocularis tar DNA binding protein 0.0077 0.0711 0.0704
Brugia malayi Ets-domain containing protein 0.0011 0.0036 0.0012
Schistosoma mansoni hypothetical protein 0.0019 0.012 0.0173
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0646 0.6529 0.8672
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.035 0.3501 0.4634
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0046 1
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0711 0.1079
Trichomonas vaginalis replication factor C large subunit, putative 0.0012 0.0046 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0035 0.0278 0.0415
Schistosoma mansoni hypothetical protein 0.0019 0.012 0.0173
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0091 0.0084
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0646 0.6529 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.0334
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0111 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0278 0.0335
Schistosoma mansoni RAR-like nuclear receptor 0.0035 0.0278 0.0415
Brugia malayi DKFZp564C0469 protein 0.0012 0.0046 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.0334
Loa Loa (eye worm) TAR-binding protein 0.0077 0.0711 0.0912
Chlamydia trachomatis DNA ligase 0.0012 0.0046 0.5
Brugia malayi conserved hypotetical protein 0.0016 0.0091 0.0086
Brugia malayi nuclear hormone receptor family member nhr-6 0.0016 0.0091 0.0086
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0711 0.1079
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0046 0.9999
Schistosoma mansoni carbonic anhydrase-related 0.035 0.3501 0.5357
Echinococcus multilocularis GPCR, family 2 0.0019 0.012 0.0113
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Echinococcus multilocularis carbonic anhydrase II 0.0646 0.6529 0.6527
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0348 0.0428
Brugia malayi Ets-domain containing protein 0.0075 0.0694 0.0891
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.012 0.0123
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0035 0.0278 0.0415
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0046 0.006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.035 0.3501 0.4633
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0035 0.0278 0.0334
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0111 0.0159
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0091 0.0128
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0046 1
Echinococcus granulosus carbonic anhydrase 0.035 0.3501 0.5357
Loa Loa (eye worm) hypothetical protein 0.0012 0.0046 0.0025
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0091 0.0128
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0635 0.0962
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0036 0.0028
Schistosoma mansoni hypothetical protein 0.0041 0.0348 0.0522
Brugia malayi nuclear hormone receptor 0.0035 0.0278 0.0335
Schistosoma mansoni ets-related 0.0011 0.0036 0.0044
Brugia malayi hypothetical protein 0.0018 0.0111 0.0113
Echinococcus multilocularis FTZ F1 alpha 0.0035 0.0278 0.0271
Treponema pallidum DNA ligase (lig) 0.0012 0.0046 0.5
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0036 0.0011
Loa Loa (eye worm) nuclear receptor NHR-67 0.0016 0.0091 0.0084
Echinococcus multilocularis nibrin 0.0012 0.0046 0.0039
Echinococcus multilocularis ets variant gene 4 0.0011 0.0036 0.0028
Brugia malayi nuclear receptor NHR-88 0.0016 0.0091 0.0086
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.035 0.3501 0.4633
Echinococcus multilocularis thyroid hormone receptor alpha 0.0035 0.0278 0.0271
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.0334
Toxoplasma gondii hypothetical protein 0.035 0.3501 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0035 0.0278 0.0335
Echinococcus multilocularis dnaJ subfamily B 0.0466 0.4697 0.4693
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0012 0.0046 0.5
Echinococcus granulosus nibrin 0.0012 0.0046 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0035 0.0278 0.0334
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0761 0.7711 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0016 0.0091 0.0084
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0012 0.0046 0.5
Brugia malayi ecdysteroid receptor 0.0035 0.0278 0.0335
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.0046 0.006
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0036 0.0028
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0091 0.0086
Echinococcus granulosus cpg binding protein 0.0035 0.0278 0.0416
Schistosoma mansoni steroid hormone receptor ad4bp 0.0035 0.0278 0.0415
Echinococcus granulosus protein C ets 2 0.0011 0.0036 0.0044
Brugia malayi steroid hormone receptor 0.0035 0.0278 0.0335
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0091 0.0084
Loa Loa (eye worm) hypothetical protein 0.0041 0.0348 0.0427
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0016 0.0091 0.0128
Echinococcus granulosus carbonic anhydrase II 0.0646 0.6529 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0016 0.0091 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0711 0.1079
Leishmania major carbonic anhydrase-like protein 0.0646 0.6529 0.5
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Onchocerca volvulus 0.0035 0.0278 0.0302
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0091 0.0084
Brugia malayi Latrophilin receptor protein 2 0.0019 0.012 0.0125
Loa Loa (eye worm) carbonic anhydrase 3 0.0646 0.6529 0.8672
Echinococcus granulosus carbonic anhydrase 0.035 0.3501 0.5357
Loa Loa (eye worm) hypothetical protein 0.035 0.3501 0.4633
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.012 0.0113
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0091 0.0128
Toxoplasma gondii ATPase, AAA family protein 0.0012 0.0046 0.00000099992
Schistosoma mansoni hypothetical protein 0.0019 0.012 0.0173
Brugia malayi CXXC zinc finger family protein 0.0033 0.0259 0.031
Schistosoma mansoni ets 0.0011 0.0036 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0278 0.0415
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0278 0.0271
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0035 0.0278 0.0271
Schistosoma mansoni hypothetical protein 0.035 0.3501 0.5357
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0036 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0035 0.0278 0.0335
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0035 0.0278 0.0335
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0278 0.0335
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.0011
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0035 0.0278 0.0415
Loa Loa (eye worm) hypothetical protein 0.0012 0.0046 0.0025
Schistosoma mansoni gabp alpha 0.0075 0.0694 0.1053
Onchocerca volvulus Protein ultraspiracle homolog 0.0035 0.0278 0.0302
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0278 0.0415
Giardia lamblia Replication factor C, subunit 1 0.0012 0.0046 0.5
Schistosoma mansoni carbonic anhydrase-related 0.035 0.3501 0.5357
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0278 0.0335
Echinococcus multilocularis carbonic anhydrase 0.035 0.3501 0.3496
Loa Loa (eye worm) hypothetical protein 0.0012 0.0046 0.0025
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0035 0.0278 0.0415
Schistosoma mansoni nuclear receptor nhr-48 0.0016 0.0091 0.0128
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0061 0.0543 0.0688
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0111 0.0104
Brugia malayi nuclear receptor RXR 0.0018 0.0111 0.0113
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0743 0.7525 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0035 0.0278 0.0335
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0035 0.0278 0.0334
Schistosoma mansoni hypothetical protein 0.0019 0.012 0.0173
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0111 0.0113
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0036 0.0011
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0111 0.0159
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Brugia malayi TAR-binding protein 0.0077 0.0711 0.0913
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0646 0.6529 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0046 0.9999
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0012 0.0046 1
Schistosoma mansoni DNA ligase IV 0.0012 0.0046 0.006
Brugia malayi hypothetical protein 0.0016 0.0091 0.0086
Schistosoma mansoni coup transcription factor 0.0035 0.0278 0.0415
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0278 0.0271
Brugia malayi Calcitonin receptor-like protein seb-1 0.0061 0.0543 0.069
Echinococcus granulosus thyroid hormone receptor alpha 0.0016 0.0091 0.0128
Brugia malayi Fli-1 protein 0.0229 0.2262 0.2982
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0016 0.0091 0.0086
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0036 0.0028
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0278 0.0415
Loa Loa (eye worm) nuclear hormone receptor 0.0016 0.0091 0.0084
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0028 0.002
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0036 0.0044
Loa Loa (eye worm) DR-78 0.0016 0.0091 0.0084
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0646 0.6529 0.8672
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0035 0.0278 0.0334
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.012 0.0173
Schistosoma mansoni cpg binding protein 0.0033 0.0259 0.0386
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0036 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0278 0.0415
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.0334
Brugia malayi topoisomerase 0.0012 0.0046 0.0027
Brugia malayi Steroid receptor seven-up type 2 0.0035 0.0278 0.0335
Echinococcus multilocularis cpg binding protein 0.0035 0.0278 0.0271
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0091 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0035 0.0278 0.0335
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0035 0.0278 0.0271
Onchocerca volvulus 0.0016 0.0091 0.0058
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0711 0.1079
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.0111
Schistosoma mansoni tar DNA-binding protein 0.0077 0.0711 0.1079
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0278 0.0335
Echinococcus granulosus ecdysone induced protein 78C 0.0035 0.0278 0.0415
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0035 0.0278 0.0271
Brugia malayi nuclear hormone receptor 0.0743 0.7525 1
Echinococcus granulosus nuclear receptor nhr 48 0.0016 0.0091 0.0128
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0694 0.0889
Brugia malayi transcription factor E74 isoform 0.0011 0.0036 0.0012
Onchocerca volvulus Bile acid receptor homolog 0.0035 0.0278 0.0302
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0046 0.0039
Schistosoma mansoni hypothetical protein 0.0466 0.4697 0.7191
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0559 0.1484
Brugia malayi RNA binding protein 0.0077 0.0711 0.0913
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0278 0.0335
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Brugia malayi nuclear receptor NHR-67 0.0016 0.0091 0.0086
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Loa Loa (eye worm) hypothetical protein 0.0012 0.0046 0.0025
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.012 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0046 0.9999
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Schistosoma mansoni carbonic anhydrase-related 0.035 0.3501 0.5357
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0036 0.0044
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0036 0.0044
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.035 0.3501 0.4634
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0061 0.0543 0.0688
Brugia malayi nuclear receptor NHR-88 0.0035 0.0278 0.0335
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0091 0.0058
Trypanosoma brucei carbonic anhydrase-like protein 0.0646 0.6529 1
Schistosoma mansoni hypothetical protein 0.0011 0.0036 0.0044
Schistosoma mansoni cpg binding protein 0.0035 0.0278 0.0416
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.035 0.3501 0.4634
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.0334
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0036 0.0044
Brugia malayi orphan nuclear receptor NR2E1 0.0016 0.0091 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0035 0.0278 0.0334
Schistosoma mansoni hypothetical protein 0.0011 0.0036 0.0044
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0035 0.0278 0.0415
Schistosoma mansoni hypothetical protein 0.0059 0.0528 0.0798
Brugia malayi ecdysone receptor 0.0016 0.0091 0.0086
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0694 0.0687
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0035 0.0278 0.0335
Plasmodium vivax replication factor C subunit 1, putative 0.0012 0.0046 0.5
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0278 0.0335
Brugia malayi nuclear hormone receptor family member odr-7 0.0016 0.0091 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0035 0.0278 0.0335
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.0334
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0046 0.9999
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0016 0.0091 0.0128
Echinococcus multilocularis carbonic anhydrase 0.035 0.3501 0.3496
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.0111
Echinococcus granulosus GPCR family 2 0.0019 0.012 0.0173
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0016 0.0091 0.0128
Echinococcus multilocularis carbonic anhydrase 0.035 0.3501 0.3496
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0035 0.0278 0.0415
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0028 0.0031
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0035 0.0278 0.0271
Schistosoma mansoni nuclear receptor 0.0016 0.0091 0.0128
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0077 0.0711 0.0912
Loa Loa (eye worm) hypothetical protein 0.0035 0.0278 0.0334
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0012 0.0046 0.5
Echinococcus granulosus FTZ F1 alpha 0.0035 0.0278 0.0415
Brugia malayi RNA recognition motif domain containing protein 0.0077 0.0711 0.0913
Schistosoma mansoni nuclear receptor 0.0016 0.0091 0.0128
Onchocerca volvulus 0.0033 0.0259 0.0278
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0036 0.0028
Loa Loa (eye worm) steroid hormone receptor 0.0035 0.0278 0.0334
Schistosoma mansoni zinc finger protein 0.0016 0.0091 0.0128
Schistosoma mansoni carbonic anhydrase 0.035 0.3501 0.5357
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0091 0.0086
Loa Loa (eye worm) hypothetical protein 0.035 0.3501 0.4633
Onchocerca volvulus 0.0016 0.0091 0.0058
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0111 0.0113
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0046 0.9999
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0012 0.0046 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0046 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0035 0.0278 0.0335
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0278 0.0415
Brugia malayi hypothetical protein 0.0012 0.0046 0.0027
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0694 0.1053
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0036 0.0011
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0084
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.012 0.0113
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0016 0.0091 0.0084
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0646 0.6529 1
Loa Loa (eye worm) fli-1 protein 0.0229 0.2262 0.2981
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0646 0.6529 1
Echinococcus granulosus dnaJ subfamily B 0.0466 0.4697 0.7191
Brugia malayi nuclear receptor RXR 0.0016 0.0091 0.0086
Schistosoma mansoni topbp1 0.0012 0.0046 0.006
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0036 0.0028
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.012 0.0123
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0061 0.0543 0.069
Loa Loa (eye worm) RNA binding protein 0.0077 0.0711 0.0912
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0035 0.0278 0.0334
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0036 0.0012
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0111 0.0111
Schistosoma mansoni elf1 0.0011 0.0036 0.0044
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0646 0.6529 0.8672
Plasmodium falciparum carbonic anhydrase 0.035 0.3501 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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