Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | hypothetical protein | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0017 | 0.0168 | 0.0302 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0021 | 0.0252 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | fmrfamide receptor | 0.0057 | 0.1033 | 0.1033 |
Trichomonas vaginalis | ferritin, putative | 0.001 | 0.0023 | 0.5 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Brugia malayi | Dopamine receptor protein 2 | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0012 | 0.0078 | 0.014 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0057 | 0.1033 | 0.1033 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Schistosoma mansoni | ferritin | 0.001 | 0.0023 | 0.0023 |
Echinococcus granulosus | sex peptide receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0017 | 0.0168 | 0.0302 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0057 | 0.1033 | 0.1033 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.006 | 0.1089 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | opsin-like receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0476 | 1 | 1 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.0326 | 0.0585 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0827 | 0.1483 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0071 | 0.134 | 0.134 |
Brugia malayi | Bromodomain containing protein | 0.0045 | 0.0766 | 0.1374 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0768 | 0.1377 |
Echinococcus granulosus | somatostatin receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0168 | 0.0302 |
Schistosoma mansoni | neuropeptide receptor | 0.0057 | 0.1033 | 0.1033 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | cpg binding protein | 0.0038 | 0.0616 | 0.0616 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Brugia malayi | Dopamine receptor | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0014 | 0.0014 |
Schistosoma mansoni | ferritin light chain | 0.001 | 0.0023 | 0.0023 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | follicle stimulating hormone receptor | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0071 | 0.1329 | 0.1329 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | neuropeptide F receptor | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | G protein-coupled receptor | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0168 | 0.0302 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | g protein coupled receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | cpg binding protein | 0.0038 | 0.0616 | 0.0616 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.176 | 0.5 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.0527 | 0.0946 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0017 | 0.0168 | 0.0302 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | steroid hormone receptor | 0.0017 | 0.0168 | 0.0302 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.176 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0014 | 0.0026 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0017 | 0.0168 | 0.0302 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0193 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Serotonin receptor | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0168 | 0.0302 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0168 | 0.0302 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0017 | 0.0168 | 0.0302 |
Schistosoma mansoni | biogenic amine receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0057 | 0.1033 | 0.1033 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.176 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0025 | 0.034 | 0.034 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | sulfakinin receptor protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | thyroid hormone receptor | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0014 | 0.0014 |
Echinococcus multilocularis | expressed protein | 0.001 | 0.0023 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.002 | 0.0237 | 0.0237 |
Echinococcus multilocularis | zinc finger protein | 0.0025 | 0.034 | 0.034 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0017 | 0.0168 | 0.0302 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0017 | 0.0168 | 0.0302 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | thyroid hormone receptor | 0.0017 | 0.0168 | 0.0168 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0042 | 0.0707 | 0.0707 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0237 | 0.0237 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0021 | 0.0252 | 0.0252 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0017 | 0.0168 | 0.0302 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0033 | 0.006 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0017 | 0.0168 | 0.0302 |
Brugia malayi | G-protein coupled receptor | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | zinc finger protein | 0.0018 | 0.0193 | 0.0193 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.176 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Echinococcus granulosus | FTZ F1 alpha | 0.0017 | 0.0168 | 0.0168 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0017 | 0.0168 | 0.0302 |
Echinococcus multilocularis | g protein coupled receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0017 | 0.0168 | 0.0168 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0028 | 0.0414 | 0.0414 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0017 | 0.0168 | 0.0168 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0017 | 0.0168 | 0.0302 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | neuropeptide receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | ferritin | 0.001 | 0.0023 | 0.0023 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0017 | 0.0168 | 0.0168 |
Brugia malayi | RE15519p | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0017 | 0.0168 | 0.0302 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0269 | 0.5572 | 1 |
Schistosoma mansoni | ferritin | 0.001 | 0.0023 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.4033 | 0.4033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | serotonin receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0017 | 0.0168 | 0.0302 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0057 | 0.1033 | 0.1033 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0057 | 0.1033 | 0.16 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | neuropeptide F receptor | 0.0057 | 0.1033 | 0.1853 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0091 | 0.176 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.0057 | 0.1033 | 0.1033 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.176 | 1 |
Schistosoma mansoni | apoferritin-2 | 0.001 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0014 | 0.0026 |
Brugia malayi | putative neuropeptide receptor | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0014 | 0.0014 |
Echinococcus multilocularis | neuropeptide receptor | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0017 | 0.0168 | 0.0168 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0017 | 0.0168 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | serotonin receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0014 | 0.0026 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0071 | 0.134 | 0.134 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | ferritin | 0.001 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0017 | 0.0168 | 0.0168 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0014 | 0.0026 |
Echinococcus granulosus | zinc finger protein | 0.0025 | 0.034 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | allatostatin A receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | peptidase Clp S14 family | 0.006 | 0.1089 | 0.1089 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0017 | 0.0168 | 0.0302 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | sex peptide receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | g protein coupled receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0017 | 0.0168 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0915 | 0.1642 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | opsin-like receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0091 | 0.176 | 0.176 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0057 | 0.1033 | 0.1033 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0091 | 0.176 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | myosin xvIII | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | nuclear hormone receptor | 0.0017 | 0.0168 | 0.0302 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | serotonin receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0014 | 0.0014 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Leishmania major | hypothetical protein, conserved | 0.0018 | 0.0193 | 0.5 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0168 | 0.0302 |
Brugia malayi | GnHR receptor homolog | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0017 | 0.0168 | 0.0168 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | orexin receptor type 2 | 0.0057 | 0.1033 | 0.1033 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Schistosoma mansoni | biogenic amine receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | fmrfamide receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0014 | 0.0014 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.006 | 0.1089 | 0.6136 |
Brugia malayi | Smad1 | 0.0009 | 0.0014 | 0.0026 |
Onchocerca volvulus | 0.0033 | 0.0527 | 0.0665 | |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | Serotonin receptor | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | ferritin | 0.001 | 0.0023 | 0.0023 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Dopamine receptor protein 1 | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | neuropeptide receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | geminin | 0.0197 | 0.4033 | 0.4033 |
Echinococcus granulosus | smad | 0.0009 | 0.0014 | 0.0014 |
Schistosoma mansoni | bromodomain containing protein | 0.0076 | 0.1429 | 0.1429 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0326 | 0.0326 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.0527 | 0.0946 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0031 | 0.0483 | 0.2648 |
Schistosoma mansoni | neuropeptide receptor | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0237 | 0.0237 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0017 | 0.0168 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0014 | 0.0014 |
Schistosoma mansoni | ferritin | 0.001 | 0.0023 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0017 | 0.0168 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | nuclear receptor NHR-88 | 0.0017 | 0.0168 | 0.0302 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0066 | 0.1226 | 0.582 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0021 | 0.0252 | 0.0252 |
Trypanosoma brucei | ISWI complex protein | 0.0018 | 0.0193 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | ferritin light chain | 0.001 | 0.0023 | 0.0023 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0057 | 0.1033 | 0.1033 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0031 | 0.0483 | 0.2648 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | cpg binding protein | 0.0038 | 0.0616 | 0.0616 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | neuropeptide s receptor | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0028 | 0.0414 | 0.0414 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0017 | 0.0168 | 0.0168 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0017 | 0.0168 | 0.0302 |
Echinococcus granulosus | allatostatin A receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0017 | 0.0168 | 0.0302 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0017 | 0.0168 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0017 | 0.0168 | 0.0302 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0017 | 0.0168 | 0.0302 |
Schistosoma mansoni | smad | 0.0009 | 0.0014 | 0.0014 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | hypothetical protein | 0.0476 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | G-protein coupled receptor | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0252 | 0.0453 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0014 | 0.0026 |
Brugia malayi | AKH receptor | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1573 | 0.2824 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0168 | 0.0302 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0091 | 0.176 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0057 | 0.1033 | 0.1853 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0017 | 0.0168 | 0.0168 |
Echinococcus multilocularis | neuropeptide receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0017 | 0.0168 | 0.0168 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0033 | 0.0033 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0014 | 0.0026 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0017 | 0.0168 | 0.0168 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0017 | 0.0168 | 0.0168 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0057 | 0.1033 | 0.16 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0017 | 0.0168 | 0.0302 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0014 | 0.0014 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.006 | 0.1089 | 0.1089 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0091 | 0.176 | 0.176 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0017 | 0.0168 | 0.0168 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0021 | 0.0252 | 0.0252 |
Schistosoma mansoni | neuropeptide receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | adenoreceptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | MH2 domain containing protein | 0.0139 | 0.2786 | 0.4999 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0014 | 0.0014 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0033 | 0.0033 |
Brugia malayi | Melatonin receptor type 1A | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0042 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0168 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | g protein coupled receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0017 | 0.0168 | 0.0168 |
Echinococcus granulosus | expressed protein | 0.001 | 0.0023 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0193 | 0.0193 |
Brugia malayi | larval opioid receptor | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.176 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | apoferritin-2 | 0.001 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | g protein coupled receptor | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0017 | 0.0168 | 0.0168 |
Brugia malayi | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | geminin | 0.0197 | 0.4033 | 0.4033 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.4033 | 0.4033 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0193 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0057 | 0.1033 | 0.1033 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 | |
Brugia malayi | ORL1-like opioid receptor | 0.0057 | 0.1033 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.176 | 0.3158 |
Schistosoma mansoni | histamine h1 receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0057 | 0.1033 | 0.1853 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0028 | 0.0414 | 0.0414 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | nuclear hormone receptor | 0.0017 | 0.0168 | 0.0168 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0014 | 0.0026 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0527 | 0.0527 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0057 | 0.1033 | 0.1033 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Bromodomain containing protein | 0.0089 | 0.1721 | 0.3088 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.006 | 0.1089 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0021 | 0.0252 | 0.0452 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0057 | 0.1033 | 0.1033 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0473 | 0.0849 |
Schistosoma mansoni | cpg binding protein | 0.0038 | 0.0616 | 0.0616 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0017 | 0.0168 | 0.0302 |
Schistosoma mansoni | biogenic amine receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0139 | 0.2786 | 0.4999 |
Schistosoma mansoni | amine GPCR | 0.0057 | 0.1033 | 0.1033 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0091 | 0.176 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0057 | 0.1033 | 0.1853 |
Echinococcus granulosus | g-protein coupled receptor | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | Probable ClpP-like protease | 0.0091 | 0.176 | 0.3158 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0014 | 0.0014 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0139 | 0.2786 | 0.4999 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.5572 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0091 | 0.176 | 0.176 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0057 | 0.1033 | 0.1033 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1033 | 0.1853 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0017 | 0.0168 | 0.0168 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0057 | 0.1033 | 0.1033 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0057 | 0.1033 | 0.1033 |
Brugia malayi | ecdysteroid receptor | 0.0269 | 0.5572 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0017 | 0.0168 | 0.0168 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0017 | 0.0168 | 0.0168 |
Echinococcus multilocularis | smad | 0.0009 | 0.0014 | 0.0014 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.002 | 0.0237 | 0.0237 |
Onchocerca volvulus | 0.0057 | 0.1033 | 0.16 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -0.61 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 0.48 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 0.56 % | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | ChEMBL. | No reference |
Inhibition (functional) | = 3 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 26 % | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
Inhibition (functional) | = 39 % | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | ChEMBL. | 20485427 |
Inhibition (functional) | = 89 % | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | ChEMBL. | 20485427 |
XC50 (functional) | = 1.04313 uM | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | ChEMBL. | 20485427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.